#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8TB24	uniprotkb:Q9Y2A7	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-389845|uniprotkb:O60329|uniprotkb:Q53QN5|uniprotkb:Q53S94|uniprotkb:Q53Y35|ensembl:ENSP00000355348	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:nckp1_human(display_long)|uniprotkb:NCKAP1(gene name)|psi-mi:NCKAP1(display_short)|uniprotkb:HEM2(gene name synonym)|uniprotkb:KIAA0587(gene name synonym)|uniprotkb:NAP1(gene name synonym)|uniprotkb:p125Nap1(gene name synonym)|uniprotkb:Membrane-associated protein HEM-2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_038464.1|refseq:NP_995314.1|ensembl:ENSG00000061676(gene)|ensembl:ENST00000361354(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031209"(SCAR complex)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031941"(filamentous actin)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR019137|mint:Q9Y2A7|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|dip:DIP-31119N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:xj4ySr6cf374UbE/gfuxMx1X0tw9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q96RU3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1111248|uniprotkb:O60301|uniprotkb:Q3MIN8|uniprotkb:Q5TC87|uniprotkb:Q5TC88|uniprotkb:Q6P658|uniprotkb:Q7LGG2|uniprotkb:Q9H8H8|uniprotkb:Q9NWD1|intact:EBI-2948562|intact:EBI-28979204|ensembl:ENSP00000413625|uniprotkb:B7ZL12|uniprotkb:E9PGQ4	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:fnbp1_human(display_long)|uniprotkb:FNBP1(gene name)|psi-mi:FNBP1(display_short)|uniprotkb:FBP17(gene name synonym)|uniprotkb:Formin-binding protein 17(gene name synonym)|uniprotkb:KIAA0554(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_055848.1|refseq:XP_005251881.1|ensembl:ENST00000355681|ensembl:ENSP00000347907|ensembl:ENST00000420781|ensembl:ENSP00000407548|ensembl:ENSP00000413625|ensembl:ENSG00000187239(gene)|ensembl:ENST00000446176(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR027267|interpro:IPR028532|interpro:IPR031160|interpro:IPR036028|interpro:IPR037449|mint:Q96RU3|rcsb pdb:2EFL|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696270|refseq:XP_005251880.1|refseq:XP_005251886.1|dip:DIP-35355N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:K6RjzNBPFl/RJmcv98TGEUCghfw9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B2R4R0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-8456746|intact:MINT-8429267	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b2r4r0_human(display_long)|uniprotkb:HIST1H4J(gene name)|psi-mi:HIST1H4J(display_short)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:hCG_1640981(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR001951(Histone H4)|refseq:NP_003537.1|refseq:NP_003532.1|refseq:NP_003529.1|refseq:NP_003536.1|refseq:NP_003530.1|refseq:NP_003486.1|refseq:NP_003531.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_001029249.1|interpro:IPR009072(Histone-fold)|refseq:NP_003533.1|refseq:NP_778224.1|interpro:IPR019809|refseq:NP_003539.1|refseq:NP_068803.1|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR035425|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0046982"(protein heterodimerization activity)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q549M8	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-8456490|intact:MINT-5002977	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q549m8_human(display_long)|uniprotkb:C14orf166(gene name)|psi-mi:C14orf166(display_short)|uniprotkb:hCG_22667(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_057123.1|interpro:IPR019265|go:"GO:0005654"(nucleoplasm)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:KRP0BO8XmEAtBag6wdctMHgVaEI9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q5JR94	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-8456376|intact:MINT-4999522	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q5jr94_human(display_long)|uniprotkb:RPS8(gene name)|psi-mi:RPS8(display_short)|uniprotkb:hCG_2031852(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR018283|refseq:NP_001003.1|interpro:IPR022309|interpro:IPR001047(Ribosomal protein S8e)|interpro:IPR042563|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022627"(cytosolic small ribosomal subunit)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:3rpCBdQyRWR+TCKnupbnCp30jKE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A3RJH1	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-8456352|intact:MINT-4839470	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a3rjh1_human(display_long)|uniprotkb:DDX1(gene name)|psi-mi:DDX1(display_short)|uniprotkb:DEAD box protein 1(gene name synonym)|uniprotkb:hCG_15914(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|refseq:NP_004930.1|interpro:IPR027417|interpro:IPR043136|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0051607"(defense response to virus)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:n2Zv07BpuUDT32/ttDzIFXH3yIQ9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P19338	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P22234	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:E7EMB3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519837|ensembl:ENSP00000387065	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:e7emb3_human(display_long)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENST00000409563(transcript)|go:"GO:0005509"(calcium ion binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|ensembl:ENSG00000143933(gene)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:5FlUEhSFAGd3DRYEbrRY7tgYKbE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q99426	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-764356|uniprotkb:O00111|uniprotkb:O00674|uniprotkb:O14728|uniprotkb:Q6FGY5|ensembl:ENSP00000221855	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:tbcb_human(display_long)|uniprotkb:Tubulin-specific chaperone B(gene name synonym)|uniprotkb:Cytoskeleton-associated protein 1(gene name synonym)|uniprotkb:Cytoskeleton-associated protein CKAPI(gene name synonym)|uniprotkb:TBCB(gene name)|psi-mi:TBCB(display_short)|uniprotkb:CG22(gene name synonym)|uniprotkb:CKAP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001272.2|refseq:NP_001287900.1|dip:DIP-34409N|ensembl:ENSG00000105254(gene)|ensembl:ENST00000221855(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007399"(nervous system development)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR000626(Ubiquitin)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR029071|interpro:IPR036859|reactome:R-HSA-389977|go:"GO:0030154"(cell differentiation)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:HHMamwtPQscu/rkhdarbQl6/hcw9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P04406	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-354056|uniprotkb:P00354|uniprotkb:Q53X65|uniprotkb:E7EUT4|ensembl:ENSP00000229239|ensembl:ENSP00000380068|ensembl:ENSP00000380070	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:g3p_human(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:OK/SW-cl.12(orf name)|uniprotkb:CDABP0047(orf name)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_002037.2|refseq:NP_001243728.1|refseq:NP_001276674.1|refseq:NP_001276675.1|dip:DIP-32521N|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P04406|rcsb pdb:1U8F|rcsb pdb:1ZNQ|rcsb pdb:2FEH|rcsb pdb:3GPD|rcsb pdb:4WNC|rcsb pdb:4WNI|rcsb pdb:6ADE|rcsb pdb:6M61|rcsb pdb:6YND|rcsb pdb:6YNE|rcsb pdb:6YNF|rcsb pdb:6YNH|reactome:R-HSA-70171|reactome:R-HSA-70263|rcsb pdb:6IQ6|ensembl:ENSG00000111640(gene)|ensembl:ENST00000229239(transcript)|ensembl:ENST00000396859(transcript)|ensembl:ENST00000396861(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0031640"(killing of cells of another organism)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:9YENN/dfKl/d0tJtfFyQp2o8eAc9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024R5Z7	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21360673	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024r5z7_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:hCG_2004404(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044354"(macropinosome)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:0004859"(phospholipase inhibitor activity)|refseq:NP_001002857.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|interpro:IPR001464(Annexin)|interpro:IPR018502|interpro:IPR018252|interpro:IPR037104|interpro:IPR002389(Annexin, type II)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B2RE46	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21354502	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b2re46_human(display_long)|uniprotkb:Ribophorin-2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:VyiYcY2yBGi7FkSabRjLHaHkV749606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q13409	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-742998|ensembl:ENSP00000380308|ensembl:ENSP00000386415|uniprotkb:Q96NG7|uniprotkb:Q96S87|uniprotkb:Q9BXZ5|uniprotkb:Q9NT58|uniprotkb:Q32LY9|uniprotkb:Q53S84|uniprotkb:Q5BJF8|uniprotkb:Q7Z4X1|uniprotkb:D3DPD4|uniprotkb:D3DPD5|uniprotkb:D3DPD6|uniprotkb:B7ZA04	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:dc1i2_human(display_long)|uniprotkb:Cytoplasmic dynein intermediate chain 2(gene name synonym)|uniprotkb:Dynein intermediate chain 2, cytosolic(gene name synonym)|uniprotkb:DYNC1I2(gene name)|psi-mi:DYNC1I2(display_short)|uniprotkb:DNCIC2(gene name synonym)|uniprotkb:DNCI2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000077380(gene)|ensembl:ENST00000397119(transcript)|ensembl:ENST00000409773(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0010970"(transport along microtubule)|go:"GO:0031982"(vesicle)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0045504"(dynein heavy chain binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR025956|interpro:IPR036322|mint:Q13409|reactome:R-HSA-380270|rcsb pdb:5JPW|reactome:R-HSA-380284|rcsb pdb:6F1T|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|rcsb pdb:6F1U|rcsb pdb:6F1Z|rcsb pdb:6F38|rcsb pdb:6F3A|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|refseq:NP_001369.1|refseq:NP_001258714.1|refseq:NP_001258717.1|refseq:NP_001258718.1|refseq:NP_001258719.1|refseq:NP_001258715.1|refseq:NP_001307811.1|refseq:NP_001307812.1|refseq:NP_001307813.1|refseq:NP_001258716.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:dTj7k9h8BQ+etwfwsE2MEY2nXRM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9H773	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-723569|intact:EBI-1384169|ensembl:ENSP00000322524	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:dctp1_human(display_long)|uniprotkb:DCTPP1(gene name)|psi-mi:DCTPP1(display_short)|uniprotkb:RS21C6(gene name synonym)|uniprotkb:CDA03(orf name)|uniprotkb:XTP3TPA(gene name synonym)|uniprotkb:Deoxycytidine-triphosphatase 1(gene name synonym)|uniprotkb:XTP3-transactivated gene A protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_077001.1|ensembl:ENST00000319285(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006253"(dCTP catabolic process)|go:"GO:0009143"(nucleoside triphosphate catabolic process)|go:"GO:0032556"(pyrimidine deoxyribonucleotide binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0047840"(dCTP diphosphatase activity)|interpro:IPR025984|mint:Q9H773|reactome:R-HSA-499943|ensembl:ENSG00000179958(gene)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:4EfV2ZU2MgDiFXShthfualZnat09606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P62081	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-354360|uniprotkb:Q6IPH1|uniprotkb:P23821|uniprotkb:P24818|uniprotkb:Q57Z92|ensembl:ENSP00000385018|ensembl:ENSP00000385286|ensembl:ENSP00000495273|ensembl:ENSP00000496654|ensembl:ENSP00000496757	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rs7_human(display_long)|uniprotkb:RPS7(gene name)|psi-mi:RPS7(display_short)|uniprotkb:Small ribosomal subunit protein eS7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001002.1|ensembl:ENSG00000171863(gene)|ensembl:ENST00000403564(transcript)|ensembl:ENST00000406376(transcript)|ensembl:ENST00000462576(transcript)|ensembl:ENST00000645674(transcript)|ensembl:ENST00000646909(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030154"(cell differentiation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000554(Ribosomal protein S7e)|mint:P62081|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6G4S	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:l4aG6I34lmzYhNapbdv2CAAwRwg9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q99873	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-78738|intact:EBI-949313|uniprotkb:A0A087X1W2|uniprotkb:H7C2I1|uniprotkb:Q15529|uniprotkb:Q99872|uniprotkb:Q99874|uniprotkb:Q9NZ04|uniprotkb:Q9NZ05|uniprotkb:Q9NZ06|ensembl:ENSP00000406162|intact:EBI-2622582|uniprotkb:B4E3C3|uniprotkb:G5E9B6|uniprotkb:Q8WUW5|uniprotkb:Q2VP93|uniprotkb:Q6LEU5|intact:EBI-11034520|intact:EBI-6137914	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:anm1_human(display_long)|uniprotkb:PRMT1(gene name)|psi-mi:PRMT1(display_short)|uniprotkb:Interferon receptor 1-bound protein 4(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT1(gene name synonym)|uniprotkb:HMT2(gene name synonym)|uniprotkb:HRMT1L2(gene name synonym)|uniprotkb:IR1B4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000126457(gene)|ensembl:ENST00000454376(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008170"(N-methyltransferase activity)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0034709"(methylosome)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q99873|rcsb pdb:6NT2|reactome:R-HSA-3214858|reactome:R-HSA-6804114|reactome:R-HSA-8936459|reactome:R-HSA-9009391|reactome:R-HSA-9018519|refseq:NP_001527.3|refseq:NP_938074.2|refseq:XP_016882223.1|refseq:XP_016882224.1|refseq:NP_001193971.1|dip:DIP-30878N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:8I7isKQC9YJTBzPz1Qve4V8l8Xg9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:H3BVG0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-20723251|ensembl:ENSP00000458101	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:h3bvg0_human(display_long)|uniprotkb:NUP93(gene name)|psi-mi:NUP93(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000102900(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0015031"(protein transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|interpro:IPR007231(Nucleoporin interacting component)|ensembl:ENST00000569842(transcript)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:zAL3KNPEvD5XxTlpSnHq1AU3hkk9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P32969	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-358122|ensembl:ENSP00000346022|ensembl:ENSP00000400467|ensembl:ENSP00000494697	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rl9_human(display_long)|uniprotkb:RPL9(gene name)|psi-mi:RPL9(display_short)|uniprotkb:RPL9P7(gene name)|psi-mi:RPL9P7(display_short)|uniprotkb:RPL9P8(gene name)|psi-mi:RPL9P8(display_short)|uniprotkb:RPL9P9(gene name)|psi-mi:RPL9P9(display_short)|uniprotkb:Large ribosomal subunit protein uL6(gene name synonym)|uniprotkb:OK/SW-cl.103(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_000652.2|refseq:NP_001020092.1|ensembl:ENSG00000163682(gene)|ensembl:ENST00000295955(transcript)|ensembl:ENST00000449470(transcript)|ensembl:ENST00000645496(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR000702(Ribosomal protein L6)|interpro:IPR002359(Ribosomal protein L6, conserved site-2)|interpro:IPR020040|interpro:IPR036789|mint:P32969|rcsb pdb:2CQL|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:v0thFydYo0aEqBblJoqQX8b7JCA9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A140VK53	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21352014	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a140vk53_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0016607"(nuclear speck)|refseq:NP_057417.3|interpro:IPR013170(mRNA splicing factor, Cwf21)|interpro:IPR024945	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:3yyPAOaCzKSCEg5guJSbq0MWrHI9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:H0Y8C6	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519817|ensembl:ENSP00000419764	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:h0y8c6_human(display_long)|uniprotkb:IPO5(gene name)|psi-mi:IPO5(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR016024(Armadillo-type fold)|interpro:IPR034085|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653|ensembl:ENSG00000065150(gene)|ensembl:ENST00000469360(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:RoCuFlO3WgKDSf39QE4wMPS4QRw9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P42677	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-356336|ensembl:ENSP00000499044|uniprotkb:Q5T4L6	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rs27_human(display_long)|uniprotkb:RPS27(gene name)|psi-mi:RPS27(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:Metallopan-stimulin 1(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS27(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001021.1|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|ensembl:ENSG00000177954(gene)|ensembl:ENST00000651669(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:P42677|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-141444|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2500257|rcsb pdb:6OM7|reactome:R-HSA-5663220|reactome:R-HSA-6791226|reactome:R-HSA-68877|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-9648025|reactome:R-HSA-975956|reactome:R-HSA-975957|dip:DIP-44182N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:OA5IWAJDBpY5FFdVnun7Sq/jI7g9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A0S2Z4G4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21355809	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a0s2z4g4_human(display_long)|uniprotkb:TPM3(gene name)|psi-mi:TPM3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|refseq:NP_705935.1|interpro:IPR000533(Tropomyosin)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:sDhDSAFlCFXE1fc07o1x9lrsubo9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:H0YFD6	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519795|ensembl:ENSP00000438039	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:h0yfd6_human(display_long)|uniprotkb:HADHA(gene name)|psi-mi:HADHA(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000084754(gene)|ensembl:ENST00000492433(transcript)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016507"(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:"GO:0070403"(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012803(Fatty acid oxidation complex, alpha subunit, mitochondrial)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:7b/RAj4/lR4boqQ5fI24pTG+/aQ9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P62280	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1047710|uniprotkb:B2R4F5|uniprotkb:P04643|uniprotkb:Q498Y6|uniprotkb:Q6IRY0|ensembl:ENSP00000270625	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rs11_human(display_long)|uniprotkb:RPS11(gene name)|psi-mi:RPS11(display_short)|uniprotkb:Small ribosomal subunit protein uS17(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001006.1|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019979|interpro:IPR028333|interpro:IPR032440|mint:P62280|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|go:"GO:0005840"(ribosome)|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|ensembl:ENSG00000142534(gene)|ensembl:ENST00000270625(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6OM0|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:0fqJjtWAuz31VTKt2mbteRoi8vA9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024R1U0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519760	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024r1u0_human(display_long)|uniprotkb:RANGAP1(gene name)|psi-mi:RANGAP1(display_short)|uniprotkb:hCG_41537(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016235"(aggresome)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0048678"(response to axon injury)|go:"GO:0072686"(mitotic spindle)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|refseq:NP_001265580.1|refseq:NP_001304859.1|refseq:NP_002874.1|refseq:XP_006724352.1|refseq:XP_011528596.1|refseq:XP_011528597.1|refseq:XP_016884382.1|refseq:XP_016884383.1|refseq:XP_016884384.1|refseq:XP_016884385.1|refseq:XP_016884386.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|interpro:IPR009109(Ran-GTPase activating protein 1, C-terminal)|interpro:IPR036720	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:pUpd+7p5CeAKaRGLo/bXTeiwjiM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024RB87	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21353832	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024rb87_human(display_long)|uniprotkb:RAP1B(gene name)|psi-mi:RAP1B(display_short)|uniprotkb:hCG_15982(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0016020"(membrane)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0035690"|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097211"(cellular response to gonadotropin-releasing hormone)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|refseq:NP_001010942.1|refseq:NP_056461.1|interpro:IPR027417|interpro:IPR038851|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR020849	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:CiuN7je+CaRH9QKDiR3vrzcJ87g9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P84098	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-916524|uniprotkb:P14118|uniprotkb:P22908|uniprotkb:Q502Y6|uniprotkb:Q7Z6E4|uniprotkb:B2R4K2|ensembl:ENSP00000225430	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rl19_human(display_long)|uniprotkb:RPL19(gene name)|psi-mi:RPL19(display_short)|uniprotkb:Large ribosomal subunit protein eL19(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_000972.1|ensembl:ENSG00000108298(gene)|ensembl:ENST00000225430(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0097421"(liver regeneration)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR000196(Ribosomal protein L19/L19e)|interpro:IPR015972(Ribosomal protein L19/L19e, domain 1)|interpro:IPR023638|interpro:IPR033935|interpro:IPR035970|interpro:IPR039547|mint:P84098|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:sYEwdB8ySbxh3iL0uqlfRRVFiWw9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B4DR52	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21357538	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b4dr52_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046982"(protein heterodimerization activity)|rcsb pdb:7BG9|interpro:IPR009072(Histone-fold)|interpro:IPR007125(Histone core)|interpro:IPR000558(Histone H2B)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:yuMvD088vLfoSAYLEcV3evV+1T09606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q96RN5	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-394506|uniprotkb:O15413|uniprotkb:Q6IC31|uniprotkb:Q8NF16|uniprotkb:Q96CT0|uniprotkb:Q96IH7|uniprotkb:Q9P1T3|uniprotkb:D3DX31|uniprotkb:D3DX32|ensembl:ENSP00000263205	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:med15_human(display_long)|uniprotkb:MED15(gene name)|psi-mi:MED15(display_short)|uniprotkb:ARC105(gene name synonym)|uniprotkb:CTG7A(gene name synonym)|uniprotkb:Mediator complex subunit 15(gene name synonym)|uniprotkb:Positive cofactor 2 glutamine/Q-rich-associated protein(gene name synonym)|uniprotkb:TPA-inducible gene 1 protein(gene name synonym)|uniprotkb:Activator-recruited cofactor 105 kDa component(gene name synonym)|uniprotkb:CTG repeat protein 7a(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 7 protein(gene name synonym)|uniprotkb:TIG1(gene name synonym)|uniprotkb:PCQAP(gene name synonym)|uniprotkb:TNRC7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001280164.1|refseq:NP_001280165.1|refseq:NP_001003891.1|refseq:NP_056973.2|ensembl:ENSG00000099917(gene)|ensembl:ENST00000263205(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|interpro:IPR019087|interpro:IPR036529|mint:Q96RN5|rcsb pdb:2GUT|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-32908N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:8dqqSCXYc7Bp56sjogz0jpbTQLI9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024R8S5	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21351322	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024r8s5_human(display_long)|uniprotkb:P4HB(gene name)|psi-mi:P4HB(display_short)|uniprotkb:hCG_95895(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0005178"(integrin binding)|go:"GO:0003756"(protein disulfide isomerase activity)|refseq:NP_000909.2|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR036249|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:rh0B38TSfTX+lvU5OyBwEbVndFA9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9NZL4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-356763|uniprotkb:O95351|uniprotkb:Q6ZNU5|uniprotkb:B3KQP0|uniprotkb:B4DG11|ensembl:ENSP00000255631|ensembl:ENSP00000398244|ensembl:ENSP00000467574	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:hpbp1_human(display_long)|uniprotkb:HSPBP1(gene name)|psi-mi:HSPBP1(display_short)|uniprotkb:HSPBP(gene name synonym)|uniprotkb:PP1845(orf name)|uniprotkb:Heat shock protein-binding protein 1(gene name synonym)|uniprotkb:Hsp70-interacting protein 1(gene name synonym)|uniprotkb:Hsp70-binding protein 2(gene name synonym)|uniprotkb:Hsp70-interacting protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001123578.1|refseq:NP_036399.3|ensembl:ENSG00000133265(gene)|ensembl:ENST00000255631(transcript)|ensembl:ENST00000433386(transcript)|ensembl:ENST00000587922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013918(Nucleotide exchange factor Fes1)|interpro:IPR016024(Armadillo-type fold)|mint:Q9NZL4|rcsb pdb:1XQR|rcsb pdb:1XQS|refseq:NP_001284529.1|refseq:XP_016882033.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:26Au2GesO5ysT/yhYX/0oOO9Md89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9Y3I0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-2107208|uniprotkb:Q6IAI0|uniprotkb:Q9BWL4|uniprotkb:Q9NTH1|uniprotkb:Q9P037|uniprotkb:Q9P0J3|uniprotkb:B2R6A8|intact:EBI-4399544|ensembl:ENSP00000216038	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rtcb_human(display_long)|uniprotkb:3'-phosphate/5'-hydroxy nucleic acid ligase(gene name synonym)|uniprotkb:C22orf28(gene name synonym)|uniprotkb:HSPC117(orf name)|uniprotkb:RTCB(gene name)|psi-mi:RTCB(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_055121.1|dip:DIP-46750N|ensembl:ENSG00000100220(gene)|ensembl:ENST00000216038(transcript)|go:"GO:0000971"(tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate)|go:"GO:0003723"(RNA binding)|go:"GO:0003972"("RNA ligase (ATP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0017166"(vinculin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR001233(Protein of unknown function UPF0027)|interpro:IPR027513|interpro:IPR036025|mint:Q9Y3I0|reactome:R-HSA-6784531	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:URuCEq/DIn6DgR3jOb5fwnpDVXE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A8K6V3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-9512475	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a8k6v3_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|refseq:NP_036558.3|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR018846|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:dVGS0qMrgg4y1EfI6o4R0OGkK1k9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:C9JEH3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21359584|ensembl:ENSP00000403343	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:c9jeh3_human(display_long)|uniprotkb:AAMP(gene name)|psi-mi:AAMP(display_short)|uniprotkb:hCG_16292(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000127837(gene)|ensembl:ENST00000444053(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0045171"(intercellular bridge)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|refseq:NP_001289474.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:5YDUq4IWc/ZP3bXxEC30vjT2+lE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:J3KPF3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21352943|ensembl:ENSP00000367123	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:j3kpf3_human(display_long)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:hCG_2016598(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003824"(catalytic activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006865"(amino acid transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:7CMH|rcsb pdb:7CMI|rcsb pdb:7DSK|rcsb pdb:7DSL|rcsb pdb:7DSN|rcsb pdb:7DSQ|ensembl:ENSG00000168003(gene)|ensembl:ENST00000377891(transcript)|refseq:NP_001012680.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:nAebtEE3hLK4IqZZqCrC5L25DFo9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q53S08	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519739|ensembl:ENSP00000490038	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rab6d_human(display_long)|uniprotkb:RAB6D(gene name)|psi-mi:RAB6D(display_short)|uniprotkb:WTH3DI(gene name synonym)|uniprotkb:Rab6-like protein WTH3DI(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000233087(gene)|ensembl:ENST00000623617(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|refseq:NP_001071105.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:sjmfctn0oGWETXjxTyM6H0MbmTE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P62851	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-353054|ensembl:ENSP00000435096|ensembl:ENSP00000486392|uniprotkb:P25111|uniprotkb:B2R4M7	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rs25_human(display_long)|uniprotkb:RPS25(gene name)|psi-mi:RPS25(display_short)|uniprotkb:Small ribosomal subunit protein eS25(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000118181(gene)|ensembl:ENSG00000280831(gene)|ensembl:ENST00000527673(transcript)|ensembl:ENST00000628770(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004977(Ribosomal protein S25)|interpro:IPR036388|mint:P62851|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y0G|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|rcsb pdb:6ZXD|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|rcsb pdb:6ZXE|reactome:R-HSA-9010553|reactome:R-HSA-9633012|rcsb pdb:6ZXF|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|refseq:NP_001019.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:7TqA4Q6+6VMzrzaUrACbwtJKfOM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B2R4C0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519730	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b2r4c0_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR028877|interpro:IPR023573|interpro:IPR021138	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:WYd5rnq3Kxv5w1tbru9Wc37F+aE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:V9HW96	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-10330207	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:v9hw96_human(display_long)|uniprotkb:HEL-S-100n(gene name)|psi-mi:HEL-S-100n(display_short)|uniprotkb:CCT2(gene name synonym)|uniprotkb:T-complex protein 1 subunit beta(gene name synonym)|uniprotkb:hCG_24460(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR027410|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027413|refseq:NP_006422.1|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0044297"(cell body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:0005524"(ATP binding)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:M0QYS1	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21357301|ensembl:ENSP00000470037	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:m0qys1_human(display_long)|uniprotkb:RPL13A(gene name)|psi-mi:RPL13A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000142541(gene)|ensembl:ENST00000467825(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0015934"(large ribosomal subunit)|interpro:IPR005755(Ribosomal protein L13, eukaryotic/archaeal)|interpro:IPR005822(Ribosomal protein L13)|interpro:IPR036899	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:paxDgSxY7m5F6ofQQmMa/DTigY49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P22314	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-709688|uniprotkb:Q96E13|uniprotkb:Q5JRR8|ensembl:ENSP00000338413|ensembl:ENSP00000366568	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:uba1_human(display_long)|uniprotkb:Ubiquitin-activating enzyme E1(gene name synonym)|uniprotkb:Protein A1S9(gene name synonym)|uniprotkb:UBA1(gene name)|psi-mi:UBA1(display_short)|uniprotkb:A1S9T(gene name synonym)|uniprotkb:UBE1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_003325.2|refseq:NP_695012.1|refseq:XP_016885269.1|refseq:XP_016885270.1|dip:DIP-33686N|ensembl:ENSG00000130985(gene)|ensembl:ENST00000335972(transcript)|ensembl:ENST00000377351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR018075|interpro:IPR018965|interpro:IPR019572|interpro:IPR032418|interpro:IPR032420|interpro:IPR033127|interpro:IPR035985|interpro:IPR038252|interpro:IPR042063|interpro:IPR042302|interpro:IPR042449|mint:P22314|rcsb pdb:4P22|rcsb pdb:6DC6|reactome:R-HSA-8866652|reactome:R-HSA-983168	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:q+vEeA0XLST0Zz173bmEt0dNbDE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P51572	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-77683|ensembl:ENSP00000343458|ensembl:ENSP00000494052|ensembl:ENSP00000499882|uniprotkb:Q13836|uniprotkb:Q96CF0|uniprotkb:D3DWV5|uniprotkb:B3KQ79	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:bap31_human(display_long)|uniprotkb:BCAP31(gene name)|psi-mi:BCAP31(display_short)|uniprotkb:BAP31(gene name synonym)|uniprotkb:p28(gene name synonym)|uniprotkb:6C6-AG tumor-associated antigen(gene name synonym)|uniprotkb:DXS1357E(gene name synonym)|uniprotkb:Protein CDM(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001132913.1|refseq:NP_005736.3|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904154"(positive regulation of retrograde protein transport, ER to cytosol)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR008417(B-cell receptor-associated 31-like)|interpro:IPR040463|interpro:IPR041672|mint:P51572|rcsb pdb:4JZL|rcsb pdb:4JZP|reactome:R-HSA-111465|reactome:R-HSA-75153|reactome:R-HSA-8980692|reactome:R-HSA-983170|ensembl:ENSG00000185825(gene)|ensembl:ENST00000345046(transcript)|ensembl:ENST00000647529(transcript)|ensembl:ENST00000672675(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044877"(protein-containing complex binding)|refseq:NP_001243376.1|refseq:NP_001132929.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:m0aN00PLZJDWA/K1vEbla1W9+S89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A8K486	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21351991	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a8k486_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0006457"(protein folding)|interpro:IPR029000|interpro:IPR024936|interpro:IPR020892|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:ZUBPkeErIonLHIXeL7ZLhuOazJs9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A1DRY3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-4311408	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a1dry3_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR018247|interpro:IPR036770|refseq:NP_001287902.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:oXf5vAP1LTlQ7fMiR/iYKYhqcT09606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:O15397	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-358808|intact:EBI-28976929|ensembl:ENSP00000256079|uniprotkb:B7Z7M3	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:ipo8_human(display_long)|uniprotkb:IPO8(gene name)|psi-mi:IPO8(display_short)|uniprotkb:RANBP8(gene name synonym)|uniprotkb:Ran-binding protein 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_006381.2|ensembl:ENSP00000256079|ensembl:ENST00000544829|ensembl:ENSP00000444520|ensembl:ENSG00000133704(gene)|ensembl:ENST00000256079(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O15397|reactome:R-HSA-5578749|refseq:NP_001177924.1|dip:DIP-44186N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:cKZQfshtWCcKP/0VfuW5CMi1YbQ9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P35268	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-354533|intact:EBI-1055963|uniprotkb:Q6IBD1|uniprotkb:B2R495|ensembl:ENSP00000346088	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rl22_human(display_long)|uniprotkb:RPL22(gene name)|psi-mi:RPL22(display_short)|uniprotkb:Heparin-binding protein HBp15(gene name synonym)|uniprotkb:Epstein-Barr virus small RNA-associated protein(gene name synonym)|uniprotkb:EBER-associated protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL22(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_000974.1|ensembl:ENSG00000116251(gene)|ensembl:ENST00000234875(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008201"(heparin binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0045182"(translation regulator activity)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099577"(regulation of translation at presynapse, modulating synaptic transmission)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002671(Ribosomal protein L22e)|interpro:IPR038526|mint:P35268|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|reactome:R-HSA-72706|rcsb pdb:6Z6L|rcsb pdb:6Z6M|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:0TVillnqDkHmdTwxIedAJCVAdzY9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B1AK44	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519716|ensembl:ENSP00000365857|ensembl:ENSP00000365860	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b1ak44_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000116670(gene)|ensembl:ENST00000376669(transcript)|ensembl:ENST00000376672(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:fcoGOiNJmfH7EfLcCzEmVaY7dkA9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B3KTS5	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-9513251	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b3kts5_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR023614|interpro:IPR030270|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR027246|refseq:NP_003365.1|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:xRPCSK9A5DzfTEZ6/w70Ou8nEcY9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A087X2H1	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21358511|ensembl:ENSP00000484981	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a087x2h1_human(display_long)|uniprotkb:HECTD1(gene name)|psi-mi:HECTD1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000092148(gene)|ensembl:ENST00000611816(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000569(HECT)|interpro:IPR002110(Ankyrin)|interpro:IPR008979(Galactose-binding like)|interpro:IPR010606(Mib-herc2)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020683|interpro:IPR035983|interpro:IPR036770|interpro:IPR037252|interpro:IPR041200	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:4ph98bKyW0dWuAqDbs8bnaF8KM89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024R9D3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519701	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024r9d3_human(display_long)|uniprotkb:RPL30(gene name)|psi-mi:RPL30(display_short)|uniprotkb:hCG_18222(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003723"(RNA binding)|refseq:NP_000980.1|interpro:IPR039109|interpro:IPR029064|interpro:IPR000231(Ribosomal protein L30e)|interpro:IPR022991|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:xR9LwYg6N7m9njT1pYumOPKZVu49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P54136	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-355482|uniprotkb:Q9BWA1|uniprotkb:B2RBS9|uniprotkb:Q53GY4|intact:EBI-28985219|ensembl:ENSP00000231572	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:syrc_human(display_long)|uniprotkb:RARS1(gene name)|psi-mi:RARS1(display_short)|uniprotkb:Arginyl-tRNA synthetase(gene name synonym)|uniprotkb:RARS(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_002878.2|ensembl:ENSG00000113643(gene)|ensembl:ENST00000231572(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004814"(arginine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006420"(arginyl-tRNA aminoacylation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0034618"(arginine binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR005148(Arginyl tRNA synthetase, class Ic, N-terminal)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR035684|interpro:IPR036695|mint:P54136|rcsb pdb:4Q2T|rcsb pdb:4Q2X|rcsb pdb:4Q2Y|rcsb pdb:4R3Z|rcsb pdb:4ZAJ|reactome:R-HSA-2408522|reactome:R-HSA-379716|ensembl:ENSP00000231572	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:oM9gWF1NucjgVjBFm4DcjmnQNCE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024R3W7	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21354052	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024r3w7_human(display_long)|uniprotkb:EEF1B2(gene name)|psi-mi:EEF1B2(display_short)|uniprotkb:hCG_2012498(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0045471"(response to ethanol)|refseq:NP_001032752.1|refseq:NP_001950.1|refseq:NP_066944.1|interpro:IPR036219|interpro:IPR018940|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|interpro:IPR036282|interpro:IPR014717(Translation elongation  factor EF1B/ribosomal protein S6)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:d4zkwQOMlpr6XBapMfT1sxy2ZPs9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q6IPI1	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21353448	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q6ipi1_human(display_long)|uniprotkb:RPL29(gene name)|psi-mi:RPL29(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR002673(Ribosomal protein L29e)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:DkgS1KAAq6pFczCsJ/OTWrdBhas9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9H7D7	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1046864|uniprotkb:A0MNN3|uniprotkb:Q4G100|uniprotkb:Q59EC4|uniprotkb:Q5GLZ9|uniprotkb:Q86UY4|uniprotkb:Q9H3C2|ensembl:ENSP00000504428|intact:EBI-1642504	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:wdr26_human(display_long)|uniprotkb:CUL4- and DDB1-associated WDR protein 2(gene name synonym)|uniprotkb:Myocardial ischemic preconditioning up-regulated protein 2(gene name synonym)|uniprotkb:WDR26(gene name)|psi-mi:WDR26(display_short)|uniprotkb:CDW2(gene name synonym)|uniprotkb:MIP2(gene name synonym)|uniprotkb:PRO0852(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9H7D7|ensembl:ENSG00000162923(gene)|ensembl:ENST00000678917(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|refseq:NP_001108585.2|refseq:NP_079436.4	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:HRA6f68aldUqB1rVa7uM9srSyR49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9HAU8	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-2855985|uniprotkb:Q6NX56|uniprotkb:Q9H033|uniprotkb:Q5XKC3|uniprotkb:Q9NVD0|uniprotkb:Q96AC9|ensembl:ENSP00000270357	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rnpl1_human(display_long)|uniprotkb:RNPEPL1(gene name)|psi-mi:RNPEPL1(display_short)|uniprotkb:Arginyl aminopeptidase-like 1(gene name synonym)|uniprotkb:Methionyl aminopeptidase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_060696.4|ensembl:ENSG00000142327(gene)|ensembl:ENST00000270357(transcript)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0070006"(metalloaminopeptidase activity)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR015211(Peptidase M1, leukotriene A4 hydrolase, aminopeptidase C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027268|interpro:IPR033525|interpro:IPR034015|interpro:IPR038502|interpro:IPR042097	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:bS/a3PL4AKRoSR+eRwKZfrjSFsI9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P22626	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:L7N2F9	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519682|ensembl:ENSP00000464383	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:l7n2f9_human(display_long)|uniprotkb:Vesicle-associated membrane protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000263620(gene)|ensembl:ENST00000498285(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0035493"(SNARE complex assembly)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR028717|interpro:IPR042855	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:VbDncgq8ZhHxsg53+EGOyiS15PE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P62913	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-354380|uniprotkb:P25121|uniprotkb:P39026|uniprotkb:Q8TDH2|uniprotkb:Q9Y674|ensembl:ENSP00000496250	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rl11_human(display_long)|uniprotkb:RPL11(gene name)|psi-mi:RPL11(display_short)|uniprotkb:CLL-associated antigen KW-12(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_000966.2|refseq:NP_001186731.1|ensembl:ENSG00000142676(gene)|ensembl:ENST00000643754(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006605"(protein targeting)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR002132(Ribosomal protein L5)|interpro:IPR020929|interpro:IPR022803|interpro:IPR031309|interpro:IPR031310|mint:P62913|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4XXB|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y6X	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:xt8XhDkfQPoH4DIPr0gC+ll766Q9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P62829	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-353303|uniprotkb:P23131|uniprotkb:Q3SWV7|uniprotkb:P24048|uniprotkb:Q29246|uniprotkb:Q6P5S1|ensembl:ENSP00000377865|ensembl:ENSP00000420311	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rl23_human(display_long)|uniprotkb:RPL23(gene name)|psi-mi:RPL23(display_short)|uniprotkb:60S ribosomal protein L17(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL14(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|reactome:R-HSA-9010553|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|refseq:NP_000969.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000218(Ribosomal protein L14b/L23e)|interpro:IPR019972|interpro:IPR036853|mint:P62829|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|ensembl:ENSG00000125691(gene)|ensembl:ENST00000394332(transcript)|ensembl:ENST00000479035(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005730"(nucleolus)|dip:DIP-33156N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:TiSVU2W4+lkwf12eb4+vG6IFlZA9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q5U5J2	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-2362512|uniprotkb:E7EN85	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q5u5j2_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:TozNRNfA8iMywoqMmMCwlSHfE489606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P51571	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1054539|uniprotkb:Q53XY1|uniprotkb:A8K378|ensembl:ENSP00000317331|ensembl:ENSP00000359103|ensembl:ENSP00000359104	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:ssrd_human(display_long)|uniprotkb:Signal sequence receptor subunit delta(gene name synonym)|uniprotkb:SSR4(gene name)|psi-mi:SSR4(display_short)|uniprotkb:TRAPD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001191455.1|refseq:NP_006271.1|refseq:XP_011529488.1|refseq:XP_011529489.1|ensembl:ENSG00000180879(gene)|ensembl:ENST00000320857(transcript)|ensembl:ENST00000370086(transcript)|ensembl:ENST00000370087(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008855(Translocon-associated)|mint:P51571|reactome:R-HSA-1799339	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:2SNgZQH/jwi61UcuHUf7RYKZH589606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:O43719	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-720468|uniprotkb:Q59G06|uniprotkb:Q99730|uniprotkb:D3DWG9|intact:EBI-28971035|ensembl:ENSP00000218364|ensembl:ENSP00000442699	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:htsf1_human(display_long)|uniprotkb:HTATSF1(gene name)|psi-mi:HTATSF1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSP00000218364|ensembl:ENSP00000442699|refseq:NP_001156752.1|refseq:NP_055315.2|refseq:XP_005262461.1|dip:DIP-42095N|ensembl:ENSG00000102241(gene)|ensembl:ENST00000218364(transcript)|ensembl:ENST00000535601(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0019079"(viral genome replication)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034392|interpro:IPR034393|interpro:IPR035979|mint:O43719|rcsb pdb:2DIT|rcsb pdb:6N3D|rcsb pdb:6N3E|rcsb pdb:6N3F|rcsb pdb:6NSX|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:PttL+7D+505QAmcHRGNsc40haPY9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P31946	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A140VJS0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519662	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a140vjs0_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|refseq:NP_001009552.1|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P29353	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-78835|uniprotkb:O15290|ensembl:ENSP00000357430|uniprotkb:Q5T180|uniprotkb:Q5T183|uniprotkb:Q5T184|uniprotkb:Q5T185|uniprotkb:Q5T186|uniprotkb:Q8N4K5|uniprotkb:Q96CL1|uniprotkb:B5BU19|uniprotkb:D3DV78	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:shc1_human(display_long)|uniprotkb:SHC1(gene name)|psi-mi:SHC1(display_short)|uniprotkb:SHC(gene name synonym)|uniprotkb:SHCA(gene name synonym)|uniprotkb:Src homology 2 domain-containing-transforming protein C1(gene name synonym)|uniprotkb:SHC-transforming protein A(gene name synonym)|uniprotkb:SHC-transforming protein 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007176"(regulation of epidermal growth factor-activated receptor activity)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0040008"(regulation of growth)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000160691(gene)|ensembl:ENST00000368445(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048408"(epidermal growth factor binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070435"(Shc-EGFR complex)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0090322"(regulation of superoxide metabolic process)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000980(SH2 motif)|interpro:IPR006019("Phosphotyrosine interaction (PID or PI)")|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029586|interpro:IPR035676|interpro:IPR036860|mint:P29353|rcsb pdb:1MIL|rcsb pdb:1N3H|rcsb pdb:1OY2|rcsb pdb:1QG1|rcsb pdb:1SHC|rcsb pdb:1TCE|rcsb pdb:1WCP|refseq:NP_001123512.1|refseq:NP_001123513.1|refseq:NP_001189788.1|refseq:NP_003020.2|refseq:NP_892113.4|reactome:R-HSA-8851805|rcsb pdb:2L1C|rcsb pdb:4JMH|rcsb pdb:4XWX|rcsb pdb:5CZI|rcsb pdb:6DM4|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-167044|reactome:R-HSA-180336|reactome:R-HSA-210993|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-354192|reactome:R-HSA-381038|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654699|reactome:R-HSA-5654704|reactome:R-HSA-5654719|reactome:R-HSA-5673001|reactome:R-HSA-74749|reactome:R-HSA-74751|reactome:R-HSA-8853659|reactome:R-HSA-8983432|reactome:R-HSA-9009391|reactome:R-HSA-9020558|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9034864|reactome:R-HSA-912526|reactome:R-HSA-9634285|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9674555|dip:DIP-699N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:fe+pniai+VLkQLjeUjcpIvdDfIM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A0S2Z471	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519647	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a0s2z471_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:hCG_25499(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0046314"(phosphocreatine biosynthetic process)|refseq:XP_016876440.1|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR022415|interpro:IPR022414|interpro:IPR022413|interpro:IPR036802|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:MvLiPdQsN2PdhXFEBak/GyKG+xo9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B4DJQ5	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519629	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b4djq5_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR044865|refseq:NP_001276032.1|refseq:NP_001276033.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR039794|interpro:IPR036055|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR036607|interpro:IPR028146	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:9MknnXrXnm3bXtksMYkS8nWy3ck9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q8IZP0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-375446|uniprotkb:O15147|uniprotkb:O76049|uniprotkb:O95060|uniprotkb:Q5W070|uniprotkb:Q5W072|uniprotkb:Q8TB63|uniprotkb:Q96S81|uniprotkb:Q9NXZ9|uniprotkb:Q9NYB8|intact:EBI-28968938|ensembl:ENSP00000365312|uniprotkb:A9Z1Y6|uniprotkb:Q5T2R3|uniprotkb:Q5T2R4|uniprotkb:Q5T2R6|uniprotkb:Q5T2R7|uniprotkb:B4DQ58|uniprotkb:Q5T2R9|uniprotkb:B3KX62|uniprotkb:H7BXI6	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:abi1_human(display_long)|uniprotkb:ABI1(gene name)|psi-mi:ABI1(display_short)|uniprotkb:SSH3BP1(gene name synonym)|uniprotkb:Abelson interactor 1(gene name synonym)|uniprotkb:Spectrin SH3 domain-binding protein 1(gene name synonym)|uniprotkb:Eps8 SH3 domain-binding protein(gene name synonym)|uniprotkb:e3B1(gene name synonym)|uniprotkb:Nap1-binding protein(gene name synonym)|uniprotkb:Abl-binding protein 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001012768.1|refseq:NP_001012769.1|refseq:NP_001012770.1|refseq:NP_001171590.1|refseq:NP_001171591.1|go:"GO:0030027"(lamellipodium)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031209"(SCAR complex)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028456|interpro:IPR028457|interpro:IPR035725|interpro:IPR036028|mint:Q8IZP0|ensembl:ENST00000376142(transcript)|go:"GO:0001756"(somitogenesis)|ensembl:ENSG00000136754(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|refseq:NP_001171592.1|refseq:NP_001171593.1|refseq:NP_001171594.1|refseq:NP_001171595.1|refseq:NP_005461.2|ensembl:ENST00000346832|ensembl:ENSP00000279599|ensembl:ENST00000359188|ensembl:ENSP00000352114|ensembl:ENST00000376137|ensembl:ENSP00000365307|ensembl:ENST00000376138|ensembl:ENSP00000365308|ensembl:ENST00000376139|ensembl:ENSP00000365309|ensembl:ENST00000376140|ensembl:ENSP00000365310|ensembl:ENSP00000365312|ensembl:ENST00000376166|ensembl:ENSP00000365336|ensembl:ENST00000376170|ensembl:ENSP00000365340|ensembl:ENST00000490841|ensembl:ENSP00000440101|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001171596.1|refseq:NP_001171587.1|dip:DIP-31118N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:mO2D5R8ZlYmsh+fXdJpaHZOssfs9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	intact:EBI-26519605	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	-	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:s4r347_human(display_short)|psi-mi:EBI-26519605(display_long)|uniprotkb:FNBP1L(gene name)|psi-mi:FNBP1L(display_short)|uniprotkb:Transducer of Cdc42-dependent actin assembly protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	uniprotkb:S4R347(uniprot-removed-ac)	-	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:GIQyXnawSk4YSt03pe7e+PRDaL49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024RBX6	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519590	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024rbx6_human(display_long)|uniprotkb:PIR(gene name)|psi-mi:PIR(display_short)|uniprotkb:hCG_15752(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005829"(cytosol)|go:"GO:0008127"(quercetin 2,3-dioxygenase activity)|go:"GO:0030099"(myeloid cell differentiation)|refseq:NP_001018119.1|refseq:NP_003653.1|interpro:IPR012093(Pirin)|interpro:IPR008778(Pirin, C-terminal)|interpro:IPR003829(Pirin, N-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR011051(Cupin, RmlC-type)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:tMJ+43Xj9n2jIU91Hia4hQKDLb89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:O43684	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1050987|uniprotkb:O43685|uniprotkb:B2R6E7|uniprotkb:A6NJ42|uniprotkb:D3DRE9|ensembl:ENSP00000357858	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:bub3_human(display_long)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001007794.1|refseq:NP_004716.1|ensembl:ENSG00000154473(gene)|ensembl:ENST00000368865(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR020472|interpro:IPR036322|mint:O43684|reactome:R-HSA-141430|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|reactome:R-HSA-141444|reactome:R-HSA-174184|reactome:R-HSA-176409|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|dip:DIP-24205N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:nqzARPql2cThSUpxSb6PuTRn51E9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B7Z6Z4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-11601909|ensembl:ENSP00000441750	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b7z6z4_human(display_long)|uniprotkb:MYL6(gene name)|psi-mi:MYL6(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000092841(gene)|ensembl:ENST00000536128(transcript)|go:"GO:0005509"(calcium ion binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:8SfcWrqeHAExMGrP6Ur0M73LVoQ9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:O95292	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001182606.1|refseq:NP_004729.1|ensembl:ENSG00000124164(gene)|ensembl:ENST00000475243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044790"(suppression of viral release by host)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|dip:DIP-39816N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q53EY4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519582	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q53ey4_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|interpro:IPR027417|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:v1WjgFPCRs0e1T6PNqDaTMxoIro9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024R0H7	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519563|uniprotkb:A0A140VKC7	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024r0h7_human(display_long)|uniprotkb:WDR77(gene name)|psi-mi:WDR77(display_short)|uniprotkb:hCG_39991(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|refseq:NP_077007.1|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:0q4wunYtHalObC8r1wphhelIpr49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P20248	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-457097|ensembl:ENSP00000274026|uniprotkb:Q2M3U6|uniprotkb:Q4W5P4|uniprotkb:Q6LER8|uniprotkb:A8K7B6	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:ccna2_human(display_long)|uniprotkb:Cyclin A(gene name synonym)|uniprotkb:CCNA2(gene name)|psi-mi:CCNA2(display_short)|uniprotkb:CCN1(gene name synonym)|uniprotkb:CCNA(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000145386(gene)|ensembl:ENST00000274026(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0033762"(response to glucagon)|refseq:NP_001228.1|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0044843"(cell cycle G1/S phase transition)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:0071373"(cellular response to luteinizing hormone stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0090102"(cochlea development)|go:"GO:0097124"(cyclin A2-CDK2 complex)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR032447|interpro:IPR036915|interpro:IPR039361|mint:P20248|rcsb pdb:1E9H|rcsb pdb:1FIN|rcsb pdb:1H1P|rcsb pdb:1FVV|rcsb pdb:1GY3|rcsb pdb:1H1Q|rcsb pdb:1H1R|rcsb pdb:1H1S|rcsb pdb:1H24|rcsb pdb:1H25|rcsb pdb:1H26|rcsb pdb:1H27|rcsb pdb:1H28|rcsb pdb:1JST|rcsb pdb:1JSU|rcsb pdb:1OGU|rcsb pdb:1OI9|rcsb pdb:1OIU|rcsb pdb:1OIY|rcsb pdb:1OKV|rcsb pdb:1OKW|rcsb pdb:1OL1|rcsb pdb:1OL2|rcsb pdb:1P5E|rcsb pdb:1PKD|rcsb pdb:1QMZ|rcsb pdb:1URC|rcsb pdb:1VYW|rcsb pdb:2BKZ|rcsb pdb:2BPM|rcsb pdb:2C4G|rcsb pdb:6SG4|rcsb pdb:7ACK|rcsb pdb:7B5L|rcsb pdb:7B5R|rcsb pdb:7LUO|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-170145|reactome:R-HSA-171319|reactome:R-HSA-174184|reactome:R-HSA-176408|reactome:R-HSA-187577|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5689880|reactome:R-HSA-5693607|reactome:R-HSA-6804116|reactome:R-HSA-6804756|reactome:R-HSA-6804757|rcsb pdb:2C5N|rcsb pdb:2C5O|rcsb pdb:2C5V|rcsb pdb:2C5X|rcsb pdb:2C6T|rcsb pdb:2CCH|rcsb pdb:2CCI|rcsb pdb:2CJM|rcsb pdb:2WIH|rcsb pdb:2I40|rcsb pdb:2IW6|rcsb pdb:2IW8|rcsb pdb:2IW9|rcsb pdb:2UUE|rcsb pdb:2WIP|rcsb pdb:2WMA|rcsb pdb:2WMB|rcsb pdb:2WPA|rcsb pdb:2WXV|rcsb pdb:2X1N|rcsb pdb:3EID|rcsb pdb:3EJ1|rcsb pdb:3EOC|rcsb pdb:3F5X|rcsb pdb:4BCK|rcsb pdb:2UZB|rcsb pdb:2UZD|rcsb pdb:2UZE|rcsb pdb:2UZL|rcsb pdb:2V22|rcsb pdb:2WEV|rcsb pdb:2WFY|rcsb pdb:2WHB|rcsb pdb:4BCM|rcsb pdb:4BCN|rcsb pdb:4BCP|rcsb pdb:4CFM|rcsb pdb:4CFN|rcsb pdb:4CFU|rcsb pdb:4CFV|rcsb pdb:4CFW|rcsb pdb:4CFX|rcsb pdb:4EOI|rcsb pdb:4EOJ|rcsb pdb:4EOK|rcsb pdb:4EOL|rcsb pdb:4EOM|rcsb pdb:4EON|rcsb pdb:4EOO|rcsb pdb:4EOP|rcsb pdb:6Q6H|rcsb pdb:4EOQ|rcsb pdb:4EOR|rcsb pdb:4EOS|rcsb pdb:4FX3|rcsb pdb:5CYI|rcsb pdb:5IF1|rcsb pdb:5LMK|rcsb pdb:5NEV|rcsb pdb:6ATH|rcsb pdb:6RIJ|rcsb pdb:6GVA|rcsb pdb:6P3W|rcsb pdb:6Q6G|reactome:R-HSA-68911|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69273|reactome:R-HSA-69563|reactome:R-HSA-69656|dip:DIP-638N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:eAkF93loT7w//7jrIC/Nlpy5iVc9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B2RDN9	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-2562871	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b2rdn9_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043564"("Ku70:Ku80 complex")|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:6RdhUHbQy+2q5/mYv70q5Teh/vc9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P15531	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-741141|ensembl:ENSP00000376892|uniprotkb:Q6FGK3|uniprotkb:Q86XQ2|uniprotkb:Q9UDJ6	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:ndka_human(display_long)|uniprotkb:Tumor metastatic process-associated protein(gene name synonym)|uniprotkb:Metastasis inhibition factor nm23(gene name synonym)|uniprotkb:Granzyme A-activated DNase(gene name synonym)|uniprotkb:NME1(gene name)|psi-mi:NME1(display_short)|uniprotkb:NDPKA(gene name synonym)|uniprotkb:NM23(gene name synonym)|uniprotkb:NM23-H1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_000260.1|refseq:NP_937818.1|ensembl:ENSG00000239672(gene)|ensembl:ENST00000393196(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014075"(response to amine)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|go:"GO:0019899"(enzyme binding)|interpro:IPR023005|go:"GO:0021766"(hippocampus development)|interpro:IPR034907|interpro:IPR036850|mint:P15531|go:"GO:0030154"(cell differentiation)|go:"GO:0032587"(ruffle membrane)|rcsb pdb:1JXV|rcsb pdb:1UCN|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|rcsb pdb:2HVD|rcsb pdb:2HVE|rcsb pdb:3L7U|rcsb pdb:4ENO|rcsb pdb:5UI4|reactome:R-HSA-499943|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|dip:DIP-39164N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Ut4gK1Xq786CaZzvqdS1eiU5op89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:J3KQN4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-15105974|ensembl:ENSP00000404375|ensembl:ENSP00000483017	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:j3kqn4_human(display_long)|uniprotkb:RPL36A(gene name)|psi-mi:RPL36A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000241343(gene)|ensembl:ENST00000427805(transcript)|ensembl:ENST00000614077(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|rcsb pdb:6W6L|rcsb pdb:6Z6L|refseq:NP_066357.2	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:gmo74tTtuIcJfiwJqC5FRZ8xCYg9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9Y5I1	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1754229|uniprotkb:O75279|uniprotkb:B2RN58|ensembl:ENSP00000381636	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:pcdab_human(display_long)|uniprotkb:PCDHA11(gene name)|psi-mi:PCDHA11(display_short)|uniprotkb:CNRS7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_061725.1|refseq:NP_114067.1|ensembl:ENSG00000249158(gene)|ensembl:ENST00000398640(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007399"(nervous system development)|interpro:IPR002126(Cadherin)|interpro:IPR013164(Cadherin, N-terminal)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR031904	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:h8Q/VSXKcIL8XIfmHQJOazDmGtU9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:G3V2S9	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519550|ensembl:ENSP00000450849	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:g3v2s9_human(display_long)|uniprotkb:SLIRP(gene name)|psi-mi:SLIRP(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034152|interpro:IPR035979|ensembl:ENST00000557431(transcript)|ensembl:ENSG00000119705(gene)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:ZYhMlqmUnCVUnmyeYVPGd/bb5Ys9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q92621	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1045046|uniprotkb:Q86YC1|uniprotkb:A6H8X3|ensembl:ENSP00000285968	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:nu205_human(display_long)|uniprotkb:Nucleoporin Nup205(gene name synonym)|uniprotkb:205 kDa nucleoporin(gene name synonym)|uniprotkb:NUP205(gene name)|psi-mi:NUP205(display_short)|uniprotkb:C7orf14(gene name synonym)|uniprotkb:KIAA0225(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000155561(gene)|ensembl:ENST00000285968(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|interpro:IPR021827|mint:Q92621|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:NP_055950.1|refseq:NP_001316363.1|dip:DIP-44021N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:5lulE2tOZ4V1UZPwkEvOo9reZWE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9UBS4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P26641	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A2R8YDT1	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519530|ensembl:ENSP00000494022	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a2r8ydt1_human(display_long)|uniprotkb:GLUL(gene name)|psi-mi:GLUL(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000135821(gene)|ensembl:ENST00000642379(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR027302|interpro:IPR027303|interpro:IPR036651	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:o7nX0qE0DFCTQHlbO2zjNICUxXY9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:D0PNI1	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-9513280	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:d0pni1_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:HEL-S-3(gene name synonym)|uniprotkb:HEL4(gene name synonym)|uniprotkb:HEL-S-93(gene name synonym)|uniprotkb:hCG_2009146(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:XP_016869299.1|refseq:XP_016869300.1|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|interpro:IPR036815|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006605"(protein targeting)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0010941"(regulation of cell death)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0035148"(tube formation)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:M0R0R2	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519514|ensembl:ENSP00000471388	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:m0r0r2_human(display_long)|uniprotkb:RPS5(gene name)|psi-mi:RPS5(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000083845(gene)|ensembl:ENST00000598495(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|interpro:IPR000235(Ribosomal protein S7)|interpro:IPR005716(Ribosomal protein S7, eukaryotic/archaeal)|interpro:IPR020606|interpro:IPR023798|interpro:IPR036823	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:XUGLDUPYynZsLlAab1sLB2Y9J0I9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:E9PL57	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-11038231|ensembl:ENSP00000431482	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:e9pl57_human(display_long)|uniprotkb:NEDD8-MDP1(gene name)|psi-mi:NEDD8-MDP1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000255526(gene)|ensembl:ENST00000534348(transcript)|go:"GO:0004721"(phosphoprotein phosphatase activity)|interpro:IPR000626(Ubiquitin)|interpro:IPR010036(Magnesium-dependent phosphatase-1)|interpro:IPR019956|interpro:IPR023214|interpro:IPR029071|interpro:IPR035679|interpro:IPR036412	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:U+AK4jrxL/+ye57tt73PaORA0CI9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B7ZLW0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519506	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b7zlw0_human(display_long)|uniprotkb:LPP(gene name)|psi-mi:LPP(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0046872"(metal ion binding)|refseq:NP_001161143.1|interpro:IPR028771|interpro:IPR001781(Zinc finger, LIM-type)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:mvSZSHkDF/khr/kSkvD947T5eVw9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P20700	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-968218|ensembl:ENSP00000261366|uniprotkb:Q3SYN7|uniprotkb:Q96EI6|uniprotkb:B2R6J6	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:lmnb1_human(display_long)|uniprotkb:LMNB1(gene name)|psi-mi:LMNB1(display_short)|uniprotkb:LMN2(gene name synonym)|uniprotkb:LMNB(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000113368(gene)|ensembl:ENST00000261366(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043274"(phospholipase binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P20700|rcsb pdb:2KPW|go:"GO:0005654"(nucleoplasm)|rcsb pdb:3JT0|rcsb pdb:3TYY|rcsb pdb:3UMN|rcsb pdb:5VVX|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|reactome:R-HSA-2559584|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-4419969|reactome:R-HSA-8862803|reactome:R-HSA-8950505|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_005564.1|dip:DIP-34897N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:ZLv4OS5VSmn3sdXB9IP98YdQ+Iw9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q15149	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-297903|intact:EBI-1103289|intact:EBI-1103265|intact:EBI-1055056|uniprotkb:Q15148|uniprotkb:Q16640|ensembl:ENSP00000323856|uniprotkb:Q6S376|intact:EBI-28976159|uniprotkb:Q6S380|intact:EBI-1103313|uniprotkb:Q6S377|uniprotkb:Q6S378|uniprotkb:Q6S379|intact:EBI-1103301|intact:EBI-1103253|uniprotkb:Q6S381|uniprotkb:Q6S382|uniprotkb:Q6S383|intact:EBI-2825763	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:plec_human(display_long)|uniprotkb:PLEC(gene name)|psi-mi:PLEC(display_short)|uniprotkb:Hemidesmosomal protein 1(gene name synonym)|uniprotkb:PLEC1(gene name synonym)|uniprotkb:Plectin-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032094"(response to food)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042060"(wound healing)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043209"(myelin sheath)|go:"GO:0043621"(protein self-association)|go:"GO:0043933"(protein-containing complex organization)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSG00000178209(gene)|ensembl:ENST00000322810(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0120193"(tight junction organization)|go:"GO:2000689"(actomyosin contractile ring assembly actin filament organization)|go:"GO:2000983"(regulation of ATP citrate synthase activity)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR005326(Plectin/S10, N-terminal)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006997"(nucleus organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010467"(gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0016020"(membrane)|go:"GO:0016528"(sarcoplasm)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0019226"(transmission of nerve impulse)|interpro:IPR030269|interpro:IPR035915|interpro:IPR018159|interpro:IPR036388|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:Q15149|rcsb pdb:1MB8|rcsb pdb:2N03|rcsb pdb:2ODU|rcsb pdb:2ODV|rcsb pdb:3F7P|rcsb pdb:3PDY|rcsb pdb:3PE0|rcsb pdb:4GDO|rcsb pdb:4Q58|rcsb pdb:4Q59|rcsb pdb:5J1F|rcsb pdb:5J1G|rcsb pdb:5J1H|rcsb pdb:5J1I|reactome:R-HSA-2022090|reactome:R-HSA-264870|reactome:R-HSA-446107|ensembl:ENST00000436759|ensembl:ENSP00000388180|ensembl:ENST00000527096|ensembl:ENSP00000434583|ensembl:ENSP00000323856|ensembl:ENST00000345136|ensembl:ENSP00000344848|ensembl:ENST00000354589|ensembl:ENSP00000346602|ensembl:ENST00000354958|ensembl:ENSP00000347044|ensembl:ENST00000356346|ensembl:ENSP00000348702|ensembl:ENST00000357649|ensembl:ENSP00000350277|ensembl:ENST00000398774|ensembl:ENSP00000381756|refseq:NP_000436.2|refseq:NP_958780.1|refseq:NP_958781.1|refseq:NP_958782.1|refseq:NP_958783.1|refseq:NP_958784.1|refseq:NP_958785.1|refseq:NP_958786.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:zbctDAOOCaJUx3WBdp85v7SI0sI9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P42773	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-711290|uniprotkb:Q8TB83|ensembl:ENSP00000262662|ensembl:ENSP00000360826|ensembl:ENSP00000379452	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:cdn2c_human(display_long)|uniprotkb:CDKN2C(gene name)|psi-mi:CDKN2C(display_short)|uniprotkb:CDKN6(gene name synonym)|uniprotkb:p18-INK4c(gene name synonym)|uniprotkb:Cyclin-dependent kinase 6 inhibitor(gene name synonym)|uniprotkb:p18-INK6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001253.1|refseq:NP_523240.1|ensembl:ENSG00000123080(gene)|ensembl:ENST00000262662(transcript)|ensembl:ENST00000371761(transcript)|ensembl:ENST00000396148(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|mint:P42773|rcsb pdb:1BU9|rcsb pdb:1G3N|rcsb pdb:1IHB|rcsb pdb:1MX2|rcsb pdb:1MX4|rcsb pdb:1MX6|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-69231	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Of2GgenNQNEF+WySg8SoGFBfYkE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024R1K7	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21351354	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024r1k7_human(display_long)|uniprotkb:YWHAH(gene name)|psi-mi:YWHAH(display_short)|uniprotkb:hCG_41511(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003779"(actin binding)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0019904"(protein domain specific binding)|refseq:NP_003396.1|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR036815|interpro:IPR023410	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:VhFYPSsW3IRC388FTlmwwN37HnU9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:D6REX3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-11079348|ensembl:ENSP00000421633	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:d6rex3_human(display_long)|uniprotkb:SEC31A(gene name)|psi-mi:SEC31A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000138674(gene)|ensembl:ENST00000505472(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024298|interpro:IPR036322|interpro:IPR040251	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:TXgUu3c6hZXKH42Cc9u6ObBW+cM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9Y266	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-357298|ensembl:ENSP00000319664|uniprotkb:Q5QP31|uniprotkb:Q5QP35|uniprotkb:Q9H0N2|uniprotkb:Q9Y2B6|intact:EBI-2555945	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:nudc_human(display_long)|uniprotkb:NUDC(gene name)|psi-mi:NUDC(display_short)|uniprotkb:Nuclear distribution protein C homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000090273(gene)|ensembl:ENST00000321265(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0030496"(midbody)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR025934|interpro:IPR032572|interpro:IPR037898|mint:Q9Y266|rcsb pdb:3QOR|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0007080"(mitotic metaphase plate congression)|reactome:R-HSA-9696270|refseq:NP_006591.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:e1Q+/+VhG73ljCc3+ibG+RZNQUM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q96AG4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|ensembl:ENSP00000225972|uniprotkb:B2RE83	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_060979.2|ensembl:ENSG00000108829(gene)|ensembl:ENST00000225972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045296"(cadherin binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q96AG4	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q6IPR3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-10974426|ensembl:ENSP00000359904|uniprotkb:B4DSP9|uniprotkb:Q8N7L1|uniprotkb:Q5HYJ0|uniprotkb:E9PGR7	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:tyw3_human(display_long)|uniprotkb:TYW3(gene name)|psi-mi:TYW3(display_short)|uniprotkb:C1orf171(gene name synonym)|uniprotkb:"tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase"(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001156388.1|refseq:NP_612476.1|refseq:XP_006710410.1|ensembl:ENSG00000162623(gene)|ensembl:ENST00000370867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008175"(tRNA methyltransferase activity)|go:"GO:0030488"(tRNA methylation)|interpro:IPR003827(Protein of unknown function DUF207)|interpro:IPR036602|reactome:R-HSA-6782861	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:ao80RQq78KxUTGGG0NnSiiS3jv09606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:K7ELC7	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519491|ensembl:ENSP00000466019	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:k7elc7_human(display_long)|uniprotkb:RPL27(gene name)|psi-mi:RPL27(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000131469(gene)|ensembl:ENST00000586277(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:sY/e/2jPIUJK12kkFbmdm5zxboY9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024R608	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21353121	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024r608_human(display_long)|uniprotkb:RPLP1(gene name)|psi-mi:RPLP1(display_short)|uniprotkb:hCG_38799(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0006414"(translational elongation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|refseq:NP_000994.1|interpro:IPR038716|interpro:IPR027534	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:rHSXz4ZCJy+JH6OrjUgHiTK85mo9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A0S2Z5B2	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519468	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a0s2z5b2_human(display_long)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)|uniprotkb:hCG_28566(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016604"(nuclear body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|refseq:NP_003646.2|interpro:IPR043531|interpro:IPR033773|interpro:IPR016197(Chromo domain-like)|interpro:IPR000953(Chromo domain)|interpro:IPR017984|interpro:IPR023780|interpro:IPR023779	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B3KTN5	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21358899	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b3ktn5_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005975"(carbohydrate metabolic process)|refseq:NP_061167.1|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR007822(Lanthionine synthetase C-like)|interpro:IPR020464	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:nAKPdE9iI/IJ8t8vM3aeqbLtWlM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A8K984	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519453	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a8k984_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0007049"(cell cycle)|go:"GO:0030261"(chromosome condensation)|refseq:NP_001252531.1|interpro:IPR027417|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR024704|interpro:IPR027120|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR036277	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:GdjEaBdWPcoWzfi1NceHCdlMAnQ9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A0J9YX62	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519436|ensembl:ENSP00000488263|ensembl:ENSP00000488740	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a0j9yx62_human(display_long)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000105993(gene)|ensembl:ENST00000459889(transcript)|ensembl:ENST00000634080(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|refseq:XP_005249572.1|refseq:XP_005249573.1|refseq:XP_011514006.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:fT7S972DiuZWFrSs88Fz80KVSmk9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9Y3U8	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1057689|uniprotkb:Q6FIG1|uniprotkb:Q9UQF6|uniprotkb:B2R4Y1|uniprotkb:D6W634|ensembl:ENSP00000252543|ensembl:ENSP00000378081|ensembl:ENSP00000462609|ensembl:ENSP00000464342	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rl36_human(display_long)|uniprotkb:RPL36(gene name)|psi-mi:RPL36(display_short)|uniprotkb:Large ribosomal subunit protein eL36(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_056229.2|refseq:NP_378669.1|reactome:R-HSA-975957|mint:Q9Y3U8|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|interpro:IPR038097|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|rcsb pdb:6Y6X|ensembl:ENSG00000130255(gene)|ensembl:ENST00000347512(transcript)|ensembl:ENST00000394580(transcript)|ensembl:ENST00000577222(transcript)|ensembl:ENST00000579649(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000509(Ribosomal protein L36e)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:lRlRMF2jV/UHr4SX95SSCFIEV+s9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:O43175	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-350495|uniprotkb:Q5SZU3|uniprotkb:Q9BQ01|ensembl:ENSP00000493175|ensembl:ENSP00000493382|uniprotkb:B2RD08	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:sera_human(display_long)|uniprotkb:PHGDH(gene name)|psi-mi:PHGDH(display_short)|uniprotkb:PGDH3(gene name synonym)|uniprotkb:2-oxoglutarate reductase(gene name synonym)|uniprotkb:Malate dehydrogenase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_006614.2|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0031175"(neuron projection development)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070314"(G1 to G0 transition)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR006236(D-3-phosphoglycerate dehydrogenase)|interpro:IPR029009|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|mint:O43175|rcsb pdb:2G76|rcsb pdb:5N53|rcsb pdb:5N6C|rcsb pdb:5NZO|rcsb pdb:5NZP|rcsb pdb:5NZQ|rcsb pdb:5OFM|rcsb pdb:5OFV|ensembl:ENSG00000092621(gene)|ensembl:ENST00000641023(transcript)|ensembl:ENST00000641597(transcript)|go:"GO:0004617"(phosphoglycerate dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006566"(threonine metabolic process)|go:"GO:0007420"(brain development)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009448"(gamma-aminobutyric acid metabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0021510"(spinal cord development)|go:"GO:0021782"(glial cell development)|go:"GO:0021915"(neural tube development)|rcsb pdb:5OFW|rcsb pdb:6CWA|rcsb pdb:6PLF|rcsb pdb:6PLG|rcsb pdb:6RIH|rcsb pdb:6RJ2|rcsb pdb:6RJ3|rcsb pdb:6RJ5|rcsb pdb:6RJ6|rcsb pdb:7CVP|reactome:R-HSA-977347	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:uzg4EVysd7/zLXBurqwTCFMvqiA9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q6IQ30	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-11602590	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q6iq30_human(display_long)|uniprotkb:PABPC4(gene name)|psi-mi:PABPC4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR003954(RNA recognition, region 1)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR035979|interpro:IPR036053	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:FRpCXYxHivtQ3Ir9Aqtw7KfpsDk9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q16629	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-398885|uniprotkb:Q564D3|intact:EBI-11107979|uniprotkb:B4DLU6|uniprotkb:G5E9M3|ensembl:ENSP00000325905	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:srsf7_human(display_long)|uniprotkb:SRSF7(gene name)|psi-mi:SRSF7(display_short)|uniprotkb:Splicing factor 9G8(gene name synonym)|uniprotkb:SFRS7(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001026854.1|refseq:NP_001182375.1|dip:DIP-31790N|ensembl:ENSG00000115875(gene)|ensembl:ENST00000313117(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034651|interpro:IPR035979|interpro:IPR036875|mint:Q16629|rcsb pdb:2HVZ|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:12lFDvstcW/ySFKb4LR8KF9AylI9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A087X0X3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21358796|ensembl:ENSP00000483715	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a087x0x3_human(display_long)|uniprotkb:HNRNPM(gene name)|psi-mi:HNRNPM(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000099783(gene)|ensembl:ENST00000620401(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024666|interpro:IPR024667|interpro:IPR034990|interpro:IPR035979	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:7Ziuss290fVTc0Si7slqasNq0As9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P51648	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1391128|uniprotkb:Q93011|uniprotkb:Q96J37|uniprotkb:Q6I9T3|ensembl:ENSP00000176643|ensembl:ENSP00000461916|ensembl:ENSP00000463637|ensembl:ENSP00000500092	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:al3a2_human(display_long)|uniprotkb:Aldehyde dehydrogenase 10(gene name synonym)|uniprotkb:Microsomal aldehyde dehydrogenase(gene name synonym)|uniprotkb:ALDH3A2(gene name)|psi-mi:ALDH3A2(display_short)|uniprotkb:ALDH10(gene name synonym)|uniprotkb:FALDH(gene name synonym)|uniprotkb:Fatty aldehyde dehydrogenase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_000373.1|refseq:NP_001026976.1|refseq:XP_011522034.1|refseq:XP_011522035.1|refseq:XP_016879845.1|refseq:XP_016879846.1|ensembl:ENST00000672357(transcript)|go:"GO:0004028"(3-chloroallyl aldehyde dehydrogenase activity)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006714"(sesquiterpenoid metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008544"(epidermis development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033306"(phytol metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0046458"(hexadecanal metabolic process)|go:"GO:0046577"(long-chain-alcohol oxidase activity)|go:"GO:0050061"(long-chain-aldehyde dehydrogenase activity)|go:"GO:0052814"(medium-chain-aldehyde dehydrogenase activity)|interpro:IPR012394("Aldehyde dehydrogenase NAD(P)-dependent")|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P51648|rcsb pdb:4QGK|reactome:R-HSA-1660661|reactome:R-HSA-389599|reactome:R-HSA-9603798|reactome:R-HSA-9609523|reactome:R-HSA-9696270|reactome:R-HSA-9696273|ensembl:ENSG00000072210(gene)|ensembl:ENST00000176643(transcript)|ensembl:ENST00000579855(transcript)|ensembl:ENST00000581518(transcript)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:ADi5/NMf5JsjzaonzFIbHZebIlQ9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9Y5M8	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-355393|uniprotkb:Q8N2D8|uniprotkb:Q6P595|ensembl:ENSP00000418401|ensembl:ENSP00000503923	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:srprb_human(display_long)|uniprotkb:SRPRB(gene name)|psi-mi:SRPRB(display_short)|uniprotkb:PSEC0230(orf name)|uniprotkb:Protein APMCF1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_067026.3|ensembl:ENSG00000144867(gene)|ensembl:ENST00000466490(transcript)|ensembl:ENST00000678299(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005785"(signal recognition particle receptor complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR019009|interpro:IPR027417|mint:Q9Y5M8|rcsb pdb:7NFX|reactome:R-HSA-1799339|reactome:R-HSA-381038|dip:DIP-50218N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:pHUdnCvOhMRYIJg//OJ+SlCard49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024R6M6	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519425	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024r6m6_human(display_long)|uniprotkb:BAG5(gene name)|psi-mi:BAG5(display_short)|uniprotkb:hCG_25497(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0051087"(chaperone binding)|refseq:NP_001015048.1|refseq:NP_004864.1|interpro:IPR039773|interpro:IPR036533|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:I5E45kk4QcYF/BEa5qh7IBeBzF09606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q5TCZ1	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-2483234|uniprotkb:O43302|uniprotkb:Q5TCZ2|uniprotkb:Q5TDQ8|uniprotkb:D3DR98|ensembl:ENSP00000358789	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:spd2a_human(display_long)|uniprotkb:Tyrosine kinase substrate with five SH3 domains(gene name synonym)|uniprotkb:SH3PXD2A(gene name)|psi-mi:SH3PXD2A(display_short)|uniprotkb:FISH(gene name synonym)|uniprotkb:KIAA0418(gene name synonym)|uniprotkb:SH3MD1(gene name synonym)|uniprotkb:SH3 multiple domains protein 1(gene name synonym)|uniprotkb:Five SH3 domain-containing protein(gene name synonym)|uniprotkb:Adapter protein TKS5(gene name synonym)|uniprotkb:TKS5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_055446.2|refseq:XP_005270351.1|ensembl:ENSG00000107957(gene)|ensembl:ENST00000369774(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002102"(podosome)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030054"(cell junction)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042995"(cell projection)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072675"(osteoclast fusion)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR034917|interpro:IPR035449|interpro:IPR035450|interpro:IPR035452|interpro:IPR035453|interpro:IPR035454|interpro:IPR036028|interpro:IPR036871|interpro:IPR037961|rcsb pdb:2DNU|rcsb pdb:2EGA|rcsb pdb:2EGC|rcsb pdb:2EKH|mint:Q5TCZ1|reactome:R-HSA-8941237|reactome:R-HSA-9013148	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:XnTFFWWCeseePTNypWPnbkI+Y6I9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9H8M2	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-10258305|uniprotkb:B4DMQ2|uniprotkb:Q9H7R9|uniprotkb:Q6UWU9|uniprotkb:A6NFY8|uniprotkb:B4DR93|uniprotkb:Q2XUS1|uniprotkb:Q8IUS4|uniprotkb:Q9H5Q5|ensembl:ENSP00000419765	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:brd9_human(display_long)|uniprotkb:BRD9(gene name)|psi-mi:BRD9(display_short)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.8(gene name synonym)|uniprotkb:UNQ3040/PRO9856(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001304880.1|refseq:NP_001009877.2|refseq:NP_076413.3|ensembl:ENSG00000028310(gene)|ensembl:ENST00000467963(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR021900|interpro:IPR036427|mint:Q9H8M2|rcsb pdb:3HME|rcsb pdb:4NQN|rcsb pdb:4UIT|rcsb pdb:4UIU|rcsb pdb:4UIV|rcsb pdb:4UIW|rcsb pdb:4XY8|rcsb pdb:4YY4|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4Z6H|rcsb pdb:4Z6I|rcsb pdb:5E9V|rcsb pdb:5EU1|rcsb pdb:5F1H|rcsb pdb:5F1L|rcsb pdb:5F25|rcsb pdb:5F2P|rcsb pdb:5I40|rcsb pdb:5I7X|rcsb pdb:5I7Y|rcsb pdb:5IGM|rcsb pdb:5IGN|rcsb pdb:5JI8|rcsb pdb:5MKY|rcsb pdb:5TWX|rcsb pdb:6BQA|rcsb pdb:6HM0|rcsb pdb:6UZF|rcsb pdb:6V0S|rcsb pdb:6V0X|rcsb pdb:6V14|rcsb pdb:6V1B|rcsb pdb:6Y7H|rcsb pdb:6Y7I|rcsb pdb:6Y7J|rcsb pdb:6Y7K|rcsb pdb:6Y7L|rcsb pdb:6YQR|rcsb pdb:6YQS|rcsb pdb:6YQW	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:5b4IZUgA/WG/HR0Rf9y1nYqs3Ho9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:O43242	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-357622|uniprotkb:Q96EI2|uniprotkb:Q9BQA4|ensembl:ENSP00000264639|uniprotkb:B4DT72|uniprotkb:B3KMW9	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:psmd3_human(display_long)|uniprotkb:PSMD3(gene name)|psi-mi:PSMD3(display_short)|uniprotkb:Proteasome subunit p58(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S3(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000108344(gene)|ensembl:ENST00000264639(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|mint:O43242|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5VHH|rcsb pdb:5VHI|reactome:R-HSA-174178|rcsb pdb:5VHS|reactome:R-HSA-174184|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-180534|rcsb pdb:6MSJ|reactome:R-HSA-180585|reactome:R-HSA-187577|rcsb pdb:6MSK|reactome:R-HSA-195253|reactome:R-HSA-202424|rcsb pdb:6WJD|reactome:R-HSA-211733|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-174084|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5607761|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8854050|refseq:NP_002800.2|dip:DIP-27571N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:C6CStW89nIAA3mzubyv5wfBwPHk9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024R254	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519413	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024r254_human(display_long)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:hCG_1987845(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|interpro:IPR030083|interpro:IPR002190(MAGE protein)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:6V2nu5eXEuFvkTZXAXYtYIHO8yg9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B4E1U9	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21354716	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b4e1u9_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0030496"(midbody)|go:"GO:0051301"(cell division)|interpro:IPR037874|interpro:IPR027417|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:pt7DIwDURegLbavrH+39eGObOfQ9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A8K070	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21353801|ensembl:ENSP00000485035	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a8k070_human(display_long)|uniprotkb:GPS1(gene name)|psi-mi:GPS1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR000717(Proteasome component region PCI)|interpro:IPR019585|interpro:IPR033008|interpro:IPR036390|go:"GO:0008180"(COP9 signalosome)|ensembl:ENSG00000169727(gene)|ensembl:ENST00000623761(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Vc5UPBw9Q1uYcF8rUQ40qP5wtHE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q8N1G4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-2509921|ensembl:ENSP00000367498|uniprotkb:Q9ULN5	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:lrc47_human(display_long)|uniprotkb:LRRC47(gene name)|psi-mi:LRRC47(display_short)|uniprotkb:KIAA1185(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000130764(gene)|ensembl:ENST00000378251(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR020825|interpro:IPR025875|interpro:IPR032675|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|refseq:NP_065761.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:aPzU//EIwK8J4it97jCw/YyKFWU9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P10599	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-594644|uniprotkb:B1ALW1|uniprotkb:O60744|uniprotkb:Q53X69|uniprotkb:Q96KI3|uniprotkb:Q9UDG5|intact:EBI-1042712|ensembl:ENSP00000363641	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:thio_human(display_long)|uniprotkb:ATL-derived factor(gene name synonym)|uniprotkb:Surface-associated sulphydryl protein(gene name synonym)|uniprotkb:TXN(gene name)|psi-mi:TXN(display_short)|uniprotkb:TRDX(gene name synonym)|uniprotkb:TRX(gene name synonym)|uniprotkb:TRX1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_003320.2|refseq:NP_001231867.1|dip:DIP-6129N|ensembl:ENSG00000136810(gene)|ensembl:ENST00000374517(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0009314"(response to radiation)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071731"(response to nitric oxide)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:2000170"(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P10599|rcsb pdb:1AIU|rcsb pdb:1AUC|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1ERT|rcsb pdb:1ERU|rcsb pdb:1ERV|rcsb pdb:1ERW|rcsb pdb:1M7T|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1TRS|rcsb pdb:1TRU|rcsb pdb:1TRV|rcsb pdb:1TRW|rcsb pdb:1W1C|rcsb pdb:1W1E|rcsb pdb:2HSH|rcsb pdb:2HXK|rcsb pdb:2IFQ|rcsb pdb:2IIY|rcsb pdb:3E3E|rcsb pdb:3KD0|rcsb pdb:3M9J|rcsb pdb:3M9K|rcsb pdb:3QFA|rcsb pdb:3QFB|rcsb pdb:3TRX|rcsb pdb:4LL1|rcsb pdb:4LL4|rcsb pdb:4OO4|rcsb pdb:4OO5|rcsb pdb:4POK|rcsb pdb:4POL|rcsb pdb:4POM|rcsb pdb:4PUF|rcsb pdb:4TRX|rcsb pdb:5DQY|reactome:R-HSA-2559580|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5628897|reactome:R-HSA-5676934|reactome:R-HSA-844456|reactome:R-HSA-9617629|reactome:R-HSA-9660826	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:5u+iJJtwAwAKXljKHnpY8h5uRkQ9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P25398	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-354542|uniprotkb:Q76M58|ensembl:ENSP00000230050	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rs12_human(display_long)|uniprotkb:RPS12(gene name)|psi-mi:RPS12(display_short)|uniprotkb:Small ribosomal subunit protein eS12(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001007.2|ensembl:ENSG00000112306(gene)|ensembl:ENST00000230050(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000530(Ribosomal protein S12e)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR029064|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72702|reactome:R-HSA-72695|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:80AIouzSdCvnLUSA7qsMp6naZ3g9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9Y5A9	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-2878081|uniprotkb:B4E1G7|uniprotkb:A6NKG4|uniprotkb:Q5VSZ9|uniprotkb:Q8TDH0|uniprotkb:Q9BUJ5|uniprotkb:A8K966|uniprotkb:D3DPM8|ensembl:ENSP00000362918|ensembl:ENSP00000444660	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:ythd2_human(display_long)|uniprotkb:HGRG8(gene name synonym)|uniprotkb:CLL-associated antigen KW-14(gene name synonym)|uniprotkb:High-glucose-regulated protein 8(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-2(gene name synonym)|uniprotkb:YTHDF2(gene name)|psi-mi:YTHDF2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001166299.1|refseq:NP_001166599.1|refseq:NP_057342.2|ensembl:ENSG00000198492(gene)|ensembl:ENST00000373812(transcript)|ensembl:ENST00000542507(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001556"(oocyte maturation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007049"(cell cycle)|go:"GO:0007276"(gamete generation)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045087"(innate immune response)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070925"(organelle assembly)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903538"(regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR007275(YT521-B-like protein)|mint:Q9Y5A9|rcsb pdb:4RDO|rcsb pdb:4WQN|rcsb pdb:4RDN	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:PF4C2t/728HqnrTyBQDJydH0G709606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P00387	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1046040|uniprotkb:O75675|uniprotkb:Q8TDL8|uniprotkb:Q8WTS8|uniprotkb:Q9UEN4|uniprotkb:Q9UEN5|uniprotkb:Q9UL55|uniprotkb:Q9UL56|uniprotkb:B1AHF2|uniprotkb:B7Z7L3|ensembl:ENSP00000338461	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:nb5r3_human(display_long)|uniprotkb:Diaphorase-1(gene name synonym)|uniprotkb:CYB5R3(gene name)|psi-mi:CYB5R3(display_short)|uniprotkb:DIA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001165132.1|refseq:NP_000389.1|refseq:NP_001123291.1|refseq:NP_015565.1|refseq:NP_001165131.1|ensembl:ENSG00000100243(gene)|ensembl:ENST00000352397(transcript)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008015"(blood circulation)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043531"(ADP binding)|go:"GO:0051287"(NAD binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|mint:P00387|rcsb pdb:1M91|rcsb pdb:1UMK|reactome:R-HSA-196836|reactome:R-HSA-211945|reactome:R-HSA-6798695|interpro:IPR039261|dip:DIP-50463N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Q8JTO6AXZ8LE4FXZAzOw2p4b6HY9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9BX66	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-433642|uniprotkb:A0AED4|uniprotkb:O43857|uniprotkb:Q7LBE5|uniprotkb:Q8IVK0|uniprotkb:Q8IVQ4|uniprotkb:Q96KF3|uniprotkb:Q96KF4|uniprotkb:Q9BX64|uniprotkb:Q9BX65|uniprotkb:Q9P2Q0|uniprotkb:Q9UFT2|uniprotkb:Q9UHN7|uniprotkb:Q9Y338|uniprotkb:A7MD40|uniprotkb:Q5T924|uniprotkb:D3DR42|uniprotkb:A6NEK3|uniprotkb:A6NID8|uniprotkb:A6NJS4|uniprotkb:Q5T923|uniprotkb:Q5T927|uniprotkb:Q5T928|uniprotkb:Q5T929|uniprotkb:Q5T930|uniprotkb:Q5T931|uniprotkb:Q5T932|ensembl:ENSP00000355136|ensembl:ENSP00000360293	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:srbs1_human(display_long)|uniprotkb:KIAA0894(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)|uniprotkb:SORBS1(gene name)|psi-mi:SORBS1(display_short)|uniprotkb:KIAA1296(gene name synonym)|uniprotkb:SH3D5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001030126.1|refseq:NP_001030127.1|refseq:NP_001030128.1|refseq:NP_001030129.1|refseq:NP_006425.2|refseq:NP_056200.1|refseq:NP_079267.1|refseq:XP_006717652.1|refseq:NP_001277223.1|refseq:NP_001277224.1|refseq:NP_001277225.1|refseq:NP_001277226.1|refseq:NP_001277227.1|rcsb pdb:2O9V|rcsb pdb:4LN2|rcsb pdb:4LNP|reactome:R-HSA-445355|ensembl:ENSG00000095637(gene)|ensembl:ENST00000361941(transcript)|ensembl:ENST00000371247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016600"(flotillin complex)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0016363"(nuclear matrix)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q9BX66|rcsb pdb:2DL3|rcsb pdb:2ECZ|rcsb pdb:2LJ0|rcsb pdb:2LJ1|rcsb pdb:2MOX|rcsb pdb:2O2W|rcsb pdb:2O31|rcsb pdb:2O9S	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:R2ONicSRiI7w0eCi4m4vbdPekL09606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024R7V6	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519401	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024r7v6_human(display_long)|uniprotkb:RAB2(gene name)|psi-mi:RAB2(display_short)|uniprotkb:hCG_40714(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|refseq:NP_002856.1|interpro:IPR027417|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:MyG011KOkAtsvE2hU/fs21CEe/M9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P13797	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-698052|uniprotkb:B1AQ09|uniprotkb:Q86YI6|uniprotkb:A8K579|uniprotkb:B4DGB4|uniprotkb:B7Z6M1|ensembl:ENSP00000348163|ensembl:ENSP00000445339	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:plst_human(display_long)|uniprotkb:T-plastin(gene name synonym)|uniprotkb:PLS3(gene name)|psi-mi:PLS3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001129497.1|refseq:NP_005023.2|refseq:XP_011535836.1|refseq:NP_001165806.1|refseq:NP_001269266.1|refseq:NP_001269267.1|ensembl:ENSG00000102024(gene)|ensembl:ENST00000355899(transcript)|ensembl:ENST00000539310(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0032432"(actin filament bundle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0060348"(bone development)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR036872|interpro:IPR039956|interpro:IPR039959|mint:P13797|rcsb pdb:1AOA|rcsb pdb:1WJO	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:RWAS8uhDHEtqdDd1gfsqDDyvvsE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q15654	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9HAV7	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1043499|uniprotkb:Q549M6|uniprotkb:B2R783|ensembl:ENSP00000264954	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:grpe1_human(display_long)|uniprotkb:Mt-GrpE#1(gene name synonym)|uniprotkb:HMGE(gene name synonym)|uniprotkb:GRPEL1(gene name)|psi-mi:GRPEL1(display_short)|uniprotkb:GREPEL1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000109519(gene)|ensembl:ENST00000264954(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR000740(GrpE nucleotide exchange factor)|interpro:IPR009012(GrpE nucleotide exchange factor, head)|interpro:IPR013805(GrpE nucleotide exchange factor, coiled-coil)|mint:Q9HAV7|reactome:R-HSA-1268020|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_079472.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:OWuX4gnZBzxgv0arSEKY9KyZZ+o9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B2RCM2	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21356792	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b2rcm2_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006429"(leucyl-tRNA aminoacylation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR004493(Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:uSn8sfLoc1zpGW+D53/1RQz4B389606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A8K2M0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-9357522	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a8k2m0_human(display_long)|uniprotkb:26S proteasome regulatory subunit 6B(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:hCG_43346(orf name)|uniprotkb:PSMC4(gene name)|psi-mi:PSMC4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR035256|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|refseq:NP_006494.1|interpro:IPR032501|interpro:IPR041569|go:"GO:0001824"(blastocyst development)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045202"(synapse)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:ZwHUFX8vJa8IPZi000dHiFtUtlM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9BVG4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-722092|ensembl:ENSP00000362456	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:pbdc1_human(display_long)|uniprotkb:PBDC1(gene name)|psi-mi:PBDC1(display_short)|uniprotkb:CXorf26(gene name synonym)|uniprotkb:Polysaccharide biosynthesis domain-containing protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_057584.2|refseq:NP_001287817.1|ensembl:ENSG00000102390(gene)|ensembl:ENST00000373358(transcript)|interpro:IPR008476(Protein of unknown function DUF757)|interpro:IPR021148|interpro:IPR023139	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:lrAfLlNkRrXqqWWD7kyAokBG9ck9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:V9HWH9	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519384	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:v9hwh9_human(display_long)|uniprotkb:HEL-S-43(gene name)|psi-mi:HEL-S-43(display_short)|uniprotkb:S100A11(gene name synonym)|uniprotkb:hCG_16921(orf name)|uniprotkb:S100 calcium-binding protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|refseq:NP_005611.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028482	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:BG1iIxIcMpumVbd2yTJwB5gy4VU9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A1U9X7U3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519371	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a1u9x7u3_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005886"(plasma membrane)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0008210"(estrogen metabolic process)|refseq:NP_055049.1|interpro:IPR036291|interpro:IPR020904|interpro:IPR002347(Glucose/ribitol dehydrogenase)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:jXKOiIp3Eh3Q/IHoLpkWQY0fjhs9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A0G2JM12	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519354|ensembl:ENSP00000478364|ensembl:ENSP00000478717	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a0g2jm12_human(display_long)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:Phosvitin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000206406(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENST00000615589(transcript)|ensembl:ENST00000621953(transcript)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019887"(protein kinase regulator activity)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|interpro:IPR038773	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:nmff/npNUIJaBl5MVBvel6r2Dro9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q01167	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-2509991|intact:EBI-28976610|ensembl:ENSP00000335677|uniprotkb:Q13624|uniprotkb:Q13623|uniprotkb:A6NEP5|uniprotkb:Q13622	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:foxk2_human(display_long)|uniprotkb:G/T-mismatch specific binding protein(gene name synonym)|uniprotkb:FOXK2(gene name)|psi-mi:FOXK2(display_short)|uniprotkb:ILF(gene name synonym)|uniprotkb:ILF1(gene name synonym)|uniprotkb:Interleukin enhancer-binding factor 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000141568(gene)|ensembl:ENST00000335255(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR018122|go:"GO:0061621"(canonical glycolysis)|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|mint:Q01167|rcsb pdb:1JXS|rcsb pdb:2C6Y|reactome:R-HSA-5689603|ensembl:ENSP00000335677|ensembl:ENST00000473637|ensembl:ENSP00000436108|refseq:NP_004505.2	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:mGYtlnM3enVAuU82j5hQ0sui3F49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:O75643	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1045395|uniprotkb:O94884|uniprotkb:Q6PX59|uniprotkb:Q8NBE6|uniprotkb:Q96IF2|uniprotkb:Q9H7S0|uniprotkb:Q6NZY0|intact:EBI-1051631|ensembl:ENSP00000317123	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:u520_human(display_long)|uniprotkb:SNRNP200(gene name)|psi-mi:SNRNP200(display_short)|uniprotkb:HELIC2(gene name synonym)|uniprotkb:KIAA0788(gene name synonym)|uniprotkb:U5 snRNP-specific 200 kDa protein(gene name synonym)|uniprotkb:Activating signal cointegrator 1 complex subunit 3-like 1(gene name synonym)|uniprotkb:BRR2 homolog(gene name synonym)|uniprotkb:ASCC3L1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_054733.2|ensembl:ENSG00000144028(gene)|ensembl:ENST00000323853(transcript)|go:"GO:0000354"(cis assembly of pre-catalytic spliceosome)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|mint:O75643|rcsb pdb:2Q0Z|rcsb pdb:3JCR|rcsb pdb:4F91|rcsb pdb:4F92|rcsb pdb:4F93|rcsb pdb:4KIT|rcsb pdb:5O9Z|rcsb pdb:5URJ|rcsb pdb:5URK|rcsb pdb:5URM|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6S8O|rcsb pdb:6S8Q|rcsb pdb:6S9I|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7BDI|rcsb pdb:7BDJ|rcsb pdb:7BDK|rcsb pdb:7BDL|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:XP_016859092.1|dip:DIP-31659N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:2ZAcbMfMlk2xWWAiy7MeCL0CHtM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P06748	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930|ensembl:ENSP00000428755	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_002511.1|refseq:NP_954654.1|refseq:NP_001032827.1|dip:DIP-30932N|ensembl:ENSG00000181163(gene)|ensembl:ENST00000296930(transcript)|ensembl:ENST00000517671(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001652"(granular component)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019843"(rRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060699"(regulation of endoribonuclease activity)|go:"GO:0060735"(regulation of eIF2 alpha phosphorylation by dsRNA)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902629"(regulation of mRNA stability involved in cellular response to UV)|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024R6H1	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519336	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024r6h1_human(display_long)|uniprotkb:SPTLC2(gene name)|psi-mi:SPTLC2(display_short)|uniprotkb:hCG_22264(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0006686"(sphingomyelin biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0046511"(sphinganine biosynthetic process)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0060612"(adipose tissue development)|refseq:NP_004854.1|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:9Y8pOwwEej+jqblWkGS0ixnNHLo9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P46776	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-350581|uniprotkb:B2R4B3|ensembl:ENSP00000346015	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rl27a_human(display_long)|uniprotkb:RPL27A(gene name)|psi-mi:RPL27A(display_short)|uniprotkb:Large ribosomal subunit protein uL15(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_000981.1|ensembl:ENSG00000166441(gene)|ensembl:ENST00000314138(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001196(Ribosomal protein L15)|interpro:IPR021131|interpro:IPR027386|interpro:IPR030878|interpro:IPR036227|mint:P46776|rcsb pdb:4BXF|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72706|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6IP6|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6OM7|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:6IP5|dip:DIP-33121N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:tUezMQBw+SWmLYq8M0pkLCF8vO89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A0C4DG17	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21351094|ensembl:ENSP00000389351	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a0c4dg17_human(display_long)|uniprotkb:RPSA(gene name)|psi-mi:RPSA(display_short)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:hCG_1997894(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000168028(gene)|ensembl:ENST00000443003(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043236"(laminin binding)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|refseq:NP_001291217.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:QAdxt9T9fJ143VdOSf4h5aoqf0Q9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q59ES3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-4289617	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q59es3_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|refseq:NP_005619.1|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR036458	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:avDxMKK1xHm4DDvCAIh4q+8AC389606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P62857	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-353027|ensembl:ENSP00000472469|uniprotkb:P25112	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rs28_human(display_long)|uniprotkb:RPS28(gene name)|psi-mi:RPS28(display_short)|uniprotkb:Small ribosomal subunit protein eS28(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	mint:P62857|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|ensembl:ENSG00000233927(gene)|ensembl:ENST00000600659(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000289(Ribosomal protein S28e)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR028626|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZM7|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001022.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:G4t8mOlzIiHEOXu+uS+AfySWAnM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q8NHP8	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-10968883|ensembl:ENSP00000280800|uniprotkb:F5H5E2	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:plbl2_human(display_long)|uniprotkb:PLBD2(gene name)|psi-mi:PLBD2(display_short)|uniprotkb:76 kDa protein(gene name synonym)|uniprotkb:LAMA-like protein 2(gene name synonym)|uniprotkb:Lamina ancestor homolog 2(gene name synonym)|uniprotkb:Phospholipase B domain-containing protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001153199.1|refseq:NP_775813.2|ensembl:ENSG00000151176(gene)|ensembl:ENST00000280800(transcript)|go:"GO:0004620"(phospholipase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007000(Laminin A)|interpro:IPR043040|interpro:IPR043041|interpro:IPR043042	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Ae7gQMoB6XQQxqLlG46cG3ijM089606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q5VZU9	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21357701|ensembl:ENSP00000365220	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q5vzu9_human(display_long)|uniprotkb:TPP2(gene name)|psi-mi:TPP2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000134900(gene)|ensembl:ENST00000376052(transcript)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0042277"(peptide binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022229|interpro:IPR022398|interpro:IPR023828|interpro:IPR034051|interpro:IPR036852|refseq:NP_001317517.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:EuhgTyIKgfuMisjBlkxmGqmZxI09606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A1U9X8P6	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519323	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a1u9x8p6_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0008270"(zinc ion binding)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR043136|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR006574(SPRY-associated)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Ii29JCGKHo1ySRm2PEhh2xDkFvE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024RBH2	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21353377	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024rbh2_human(display_long)|uniprotkb:CKAP4(gene name)|psi-mi:CKAP4(display_short)|uniprotkb:hCG_16102(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|refseq:NP_006816.2|interpro:IPR028428	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Q1hrxqh5k4Myf7J0To8Ecm/xxs49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q59GX9	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519314	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q59gx9_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|interpro:IPR005485(Ribosomal protein L5, eukaryotic)|interpro:IPR025607	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:wKti1Tfo3zBMMOzuulDSWgY93MM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P30049	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1049505|uniprotkb:Q6FG90|uniprotkb:D6W5Y3|ensembl:ENSP00000215375|ensembl:ENSP00000378995|ensembl:ENSP00000464863	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:atpd_human(display_long)|uniprotkb:ATP5F1D(gene name)|psi-mi:ATP5F1D(display_short)|uniprotkb:ATP synthase F1 subunit delta(gene name synonym)|uniprotkb:ATP5D(gene name synonym)|uniprotkb:F-ATPase delta subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001001975.1|refseq:NP_001678.1|ensembl:ENSG00000099624(gene)|ensembl:ENST00000215375(transcript)|ensembl:ENST00000395633(transcript)|ensembl:ENST00000591660(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009060"(aerobic respiration)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046688"(response to copper ion)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR001469(ATPase, F1 complex, delta/epsilon subunit)|interpro:IPR020546|interpro:IPR036771|interpro:IPR036794|mint:P30049|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:OA8if7wpjwV6hkkaLqPyz6YDljc9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q6ZP66	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519311	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q6zp66_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	-	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:1i18pfdUgM1qBNCGAS2NSXMIqy49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q53EZ4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A8K4W2	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21352520	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a8k4w2_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|interpro:IPR008688(ATPase, F0 complex, subunit B, mitochondrial)|interpro:IPR013837(ATPase, F0 complex subunit B, mitochondrial, metazoa)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:fDsdQ5qtVH/eKcE96KWtO0LV+kI9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q6PID8	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-3201175|uniprotkb:Q86Y99|uniprotkb:Q92554|ensembl:ENSP00000334140	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:kld10_human(display_long)|uniprotkb:KLHDC10(gene name)|psi-mi:KLHDC10(display_short)|uniprotkb:KIAA0265(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_055812.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0140627"(ubiquitin-dependent protein catabolic process via the C-end degron rule pathway)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR015915(Kelch-type beta propeller)|mint:Q6PID8|ensembl:ENSG00000128607(gene)|ensembl:ENST00000335420(transcript)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:3uIxELU4dOhu3brVaF2yvzyy+hI9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:D3DSR7	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519302	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:d3dsr7_human(display_long)|uniprotkb:BIN3(gene name)|psi-mi:BIN3(display_short)|uniprotkb:hCG_15995(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005737"(cytoplasm)|interpro:IPR027267|interpro:IPR004148(BAR)|interpro:IPR037428	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Z0rmrLyznmxv0wbk51spxS2ORSo9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:F8W727	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21357830|ensembl:ENSP00000339064	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:f8w727_human(display_long)|uniprotkb:RPL32(gene name)|psi-mi:RPL32(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000144713(gene)|ensembl:ENST00000273223(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR001515(Ribosomal protein L32e)|interpro:IPR036351	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:1ck7tnwsd2N9kar2tlmb0Fh1Whg9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024R866	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519291	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024r866_human(display_long)|uniprotkb:RPL35(gene name)|psi-mi:RPL35(display_short)|uniprotkb:hCG_2021297(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR001854(Ribosomal protein L29)|interpro:IPR036049|interpro:IPR018254	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:2xDvj7kfmz6Dbd+lGmyaDkG5/Yg9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P81605	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P35606	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1056534|uniprotkb:B4DZI8|intact:EBI-11019844|ensembl:ENSP00000329419	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:copb2_human(display_long)|uniprotkb:COPB2(gene name)|psi-mi:COPB2(display_short)|uniprotkb:Beta'-coat protein(gene name synonym)|uniprotkb:p102(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_004757.1|ensembl:ENSG00000184432(gene)|ensembl:ENST00000333188(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:1901998"(toxin transport)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|mint:P35606|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:XP_016863001.1|dip:DIP-27603N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:zkd7lOeV+OvHglnAJg6cXoMhgbg9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P52701	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-395529|uniprotkb:O43706|uniprotkb:O43917|uniprotkb:Q8TCX4|uniprotkb:Q9BTB5|ensembl:ENSP00000234420|uniprotkb:B4DF41|uniprotkb:B4E3I4|uniprotkb:F5H2F9	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:msh6_human(display_long)|uniprotkb:MSH6(gene name)|psi-mi:MSH6(display_short)|uniprotkb:MutS-alpha 160 kDa subunit(gene name synonym)|uniprotkb:G/T mismatch-binding protein(gene name synonym)|uniprotkb:GTBP(gene name synonym)|uniprotkb:MutS protein homolog 6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_000170.1|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009411"(response to UV)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|mint:P52701|rcsb pdb:2GFU|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:6OQM|reactome:R-HSA-5358565|reactome:R-HSA-5632928|reactome:R-HSA-5632968|ensembl:ENSG00000116062(gene)|ensembl:ENST00000234420(transcript)|refseq:NP_001268421.1|refseq:NP_001268422.1|refseq:NP_001268423.1|dip:DIP-32972N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:YPpiWmh4fSjXapWgA/rXbMrLAGg9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A8K3B6	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21359553	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a8k3b6_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|refseq:NP_001120662.1|interpro:IPR035027|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR000980(SH2 motif)|interpro:IPR036860|interpro:IPR036028|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:R0FwAwsHKia91PtAx5mm/XCvp/g9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:V5YQL4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519262	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:v5yql4_human(display_long)|uniprotkb:FGFR2-AHCYL1(gene name)|psi-mi:FGFR2-AHCYL1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0004013"(adenosylhomocysteinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|interpro:IPR042172|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR041159|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036291|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020082|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:ECs8Ob6DkGpZ0IGPFXjGvGuown89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P13647	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-702187|uniprotkb:Q6PI71|uniprotkb:Q6UBJ0|uniprotkb:Q8TA91|ensembl:ENSP00000252242	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:k2c5_human(display_long)|uniprotkb:Cytokeratin-5(gene name synonym)|uniprotkb:58 kDa cytokeratin(gene name synonym)|uniprotkb:KRT5(gene name)|psi-mi:KRT5(display_short)|uniprotkb:Keratin-5(gene name synonym)|uniprotkb:Type-II keratin Kb5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_000415.2|dip:DIP-39N|ensembl:ENSG00000186081(gene)|ensembl:ENST00000252242(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0045095"(keratin filament)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P13647|rcsb pdb:3TNU|rcsb pdb:6JFV|reactome:R-HSA-446107|reactome:R-HSA-6805567|reactome:R-HSA-6809371	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:BdtVgSlWFYS/+zyXLNxvrcSWc4I9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P51784	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-306876|intact:EBI-1058416|uniprotkb:Q8IUG6|uniprotkb:Q9BWE1|uniprotkb:B2RTX1|ensembl:ENSP00000218348	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:ubp11_human(display_long)|uniprotkb:USP11(gene name)|psi-mi:USP11(display_short)|uniprotkb:UHX1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 11(gene name synonym)|uniprotkb:Deubiquitinating enzyme 11(gene name synonym)|uniprotkb:Ubiquitin thioesterase 11(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000102226(gene)|ensembl:ENST00000218348(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:P51784|rcsb pdb:4MEL|rcsb pdb:5OK6|reactome:R-HSA-390471|reactome:R-HSA-5689880|refseq:NP_004642.2|refseq:XP_011542290.1|refseq:XP_005272731.1|dip:DIP-27567N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:OSJLLFBf1ofw8SC01p2iiIM1oJo9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q00325	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325	-	-	crc64:78714C85931B22D5	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B2R6F9	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-9977560	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b2r6f9_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017892|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:bu/URutAa73ZLvRzcZ8YCalX17Y9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q86X55	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-2339854|uniprotkb:A6NN38|ensembl:ENSP00000325690	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:carm1_human(display_long)|uniprotkb:CARM1(gene name)|psi-mi:CARM1(display_short)|uniprotkb:PRMT4(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 4(gene name synonym)|uniprotkb:Coactivator-associated arginine methyltransferase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_954592.1|refseq:XP_005259765.1|dip:DIP-44071N|ensembl:ENSG00000142453(gene)|ensembl:ENST00000327064(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0034971"(histone H3-R17 methylation)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0035642"("histone methyltransferase activity (H3-R17 specific)")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:1902415"(regulation of mRNA binding)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020989|interpro:IPR025799|interpro:IPR029063|mint:Q86X55|rcsb pdb:2Y1W|rcsb pdb:2Y1X|rcsb pdb:4IKP|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5DX1|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5DXJ|rcsb pdb:5U4X|rcsb pdb:6ARJ|rcsb pdb:6ARV|rcsb pdb:6D2L|rcsb pdb:6DVR|rcsb pdb:6IZQ|rcsb pdb:6S70|rcsb pdb:6S71|rcsb pdb:6S74|rcsb pdb:6S77|rcsb pdb:6S79|rcsb pdb:6S7A|rcsb pdb:6S7B|rcsb pdb:6S7C|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-6804114|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|go:"GO:0051591"(response to cAMP)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:1x1bUjqcA/ZpmrSsSM545ReYH2A9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q5U0I6	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-9512746|uniprotkb:D6W5F3	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q5u0i6_human(display_long)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:hCG_22592(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_004152.1|interpro:IPR027417|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016477"(cell migration)|go:"GO:0032402"(melanosome transport)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042470"(melanosome)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9NQH7	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1171467|uniprotkb:Q6I9V9|uniprotkb:Q8NDA6|uniprotkb:Q9BV27|uniprotkb:Q9BVH0|uniprotkb:B7Z790|uniprotkb:B7Z7B2|uniprotkb:B2R9G1|intact:EBI-2562323|ensembl:ENSP00000349658	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:xpp3_human(display_long)|uniprotkb:Aminopeptidase P3(gene name synonym)|uniprotkb:XPNPEP3(gene name)|psi-mi:XPNPEP3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_071381.1|ensembl:ENSG00000196236(gene)|ensembl:ENST00000357137(transcript)|go:"GO:0003094"(glomerular filtration)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0016485"(protein processing)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0070006"(metalloaminopeptidase activity)|interpro:IPR007865(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P  N-terminal)|interpro:IPR029149|interpro:IPR036005|rcsb pdb:5X49|interpro:IPR000994(Peptidase M24, catalytic core)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:hRjwsoqTVtJ1YTaVzYWomQGmJOE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:O75533	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-876542|ensembl:ENSP00000335321|uniprotkb:E9PCH3	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:sf3b1_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SF3b 155 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 155(gene name synonym)|uniprotkb:SF3B1(gene name)|psi-mi:SF3B1(display_short)|uniprotkb:SAP155(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000115524(gene)|ensembl:ENST00000335508(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0034693"(U11/U12 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015016(Splicing factor 3B subunit 1)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038737|mint:O75533|rcsb pdb:2F9D|rcsb pdb:2F9J|rcsb pdb:2FHO|rcsb pdb:2PEH|rcsb pdb:3LQV|rcsb pdb:4OZ1|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6N3E|refseq:NP_036565.2|dip:DIP-29411N|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-5250924|reactome:R-HSA-72163|reactome:R-HSA-72165	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:2KqZNVdZoItavA0DFR3zZ16U0tI9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P21912	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1056481|uniprotkb:Q9NQ12|uniprotkb:Q0QEY7|uniprotkb:B2R545|ensembl:ENSP00000364649	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:sdhb_human(display_long)|uniprotkb:SDHB(gene name)|psi-mi:SDHB(display_short)|uniprotkb:SDH(gene name synonym)|uniprotkb:SDH1(gene name synonym)|uniprotkb:Iron-sulfur subunit of complex II(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_002991.2|ensembl:ENSG00000117118(gene)|ensembl:ENST00000375499(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048039"(ubiquinone binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001041(Ferredoxin)|interpro:IPR004489(Succinate dehydrogenase/fumarate reductase iron-sulphur protein)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR017896|interpro:IPR017900|interpro:IPR025192|interpro:IPR036010|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-39666N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:7xnswe3IVEFJiXqGhxF0Az3EmvE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:O43414	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-9679612|uniprotkb:B1AK98|uniprotkb:Q5T2T7|uniprotkb:Q5T2T9|uniprotkb:Q5TG35|uniprotkb:Q9BQA0|uniprotkb:Q9UEB4|ensembl:ENSP00000361331	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:eri3_human(display_long)|uniprotkb:ERI3(gene name)|psi-mi:ERI3(display_short)|uniprotkb:PINT1(gene name synonym)|uniprotkb:PRNPIP(gene name synonym)|uniprotkb:PRNPIP1(gene name synonym)|uniprotkb:Prion interactor 1(gene name synonym)|uniprotkb:Prion protein-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001288627.1|refseq:NP_001288628.1|refseq:NP_001288629.1|refseq:NP_001288630.1|ensembl:ENSP00000361331|ensembl:ENST00000372259|ensembl:ENSP00000361333|refseq:NP_076971.1|ensembl:ENSG00000117419(gene)|ensembl:ENST00000372257(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR036397|mint:O43414|rcsb pdb:2XRI	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Ke3BT8EH5uiVr+FunIbBBwvh/bM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024R0E2	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21358614	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024r0e2_human(display_long)|uniprotkb:CSDE1(gene name)|psi-mi:CSDE1(display_short)|uniprotkb:hCG_38456(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003676"(nucleic acid binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|refseq:NP_001007554.1|refseq:NP_001229821.1|interpro:IPR019844|interpro:IPR011129(Cold shock protein)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR024642	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:fpL1bONjNXyXjIO/akUIIoeEGTc9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B7Z4C8	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21356063|ensembl:ENSP00000386737	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b7z4c8_human(display_long)|uniprotkb:RPL31(gene name)|psi-mi:RPL31(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000071082(gene)|ensembl:ENST00000409038(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR000054(Ribosomal protein L31e)|interpro:IPR020052|interpro:IPR023621	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:gqQnLryhx4Y3sOxB3v36P/MNJ4I9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q15366	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P15880	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-443446|ensembl:ENSP00000341885|uniprotkb:Q3MIB1|uniprotkb:B2R5G0|uniprotkb:D3DU82	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rs2_human(display_long)|uniprotkb:RPS2(gene name)|psi-mi:RPS2(display_short)|uniprotkb:RPS4(gene name synonym)|uniprotkb:40S ribosomal protein S4(gene name synonym)|uniprotkb:Protein LLRep3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|rcsb pdb:6OLG|rcsb pdb:6OLI|interpro:IPR018192|rcsb pdb:6OLZ|interpro:IPR020568|mint:P15880|rcsb pdb:4UG0|rcsb pdb:6OM0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6XA1|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6G5H|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7JQB|rcsb pdb:7JQC|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-3214858|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8876725|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:7A09|ensembl:ENSG00000140988(gene)|ensembl:ENST00000343262(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045296"(cadherin binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR005711(Ribosomal protein S5, eukaryotic/archaeal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|refseq:NP_002943.2	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:JUr2Y3cGk00S8KaTVPymshfaHhc9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P53621	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-356273|intact:EBI-1188425|uniprotkb:Q5T201|uniprotkb:Q8IXZ9|intact:EBI-2559704|intact:EBI-11576606|ensembl:ENSP00000241704	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:copa_human(display_long)|uniprotkb:COPA(gene name)|psi-mi:COPA(display_short)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:HEP-COP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001091868.1|refseq:NP_004362.2|ensembl:ENSG00000122218(gene)|ensembl:ENST00000241704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005179"(hormone activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030426"(growth cone)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:P53621|rcsb pdb:6PBG|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:9uP/NS7FjPrGDna1wcNHQy9py6A9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q59GY2	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-11602791	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q59gy2_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR025755|interpro:IPR002136(Ribosomal protein L4/L1e)|interpro:IPR013000(Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site)|interpro:IPR023574|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:u1Ed48vbTcz+Bk+5iqLPL7On61I9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:O95202	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1052895|uniprotkb:Q9UF65|uniprotkb:B4DED2|ensembl:ENSP00000305653	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:letm1_human(display_long)|uniprotkb:Leucine zipper-EF-hand-containing transmembrane protein 1(gene name synonym)|uniprotkb:LETM1(gene name)|psi-mi:LETM1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_036450.1|ensembl:ENSG00000168924(gene)|ensembl:ENST00000302787(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006875"(cellular metal ion homeostasis)|go:"GO:0015369"("calcium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042407"(cristae formation)|go:"GO:0043022"(ribosome binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0099093"(calcium export from the mitochondrion)|go:"GO:1900069"(regulation of cellular hyperosmotic salinity response)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011685(LETM1-like)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR033122|interpro:IPR044202|reactome:R-HSA-8949215|reactome:R-HSA-9013408	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:mDxqXWqmgCjbaZLz4JqteqjDCik9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q14165	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1046466|ensembl:ENSP00000228506	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:mlec_human(display_long)|uniprotkb:MLEC(gene name)|psi-mi:MLEC(display_short)|uniprotkb:KIAA0152(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000110917(gene)|ensembl:ENST00000228506(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0035579"(specific granule membrane)|interpro:IPR021720|interpro:IPR039155|rcsb pdb:6S7T|reactome:R-HSA-532668|reactome:R-HSA-6798695|refseq:NP_055545.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:bEjayZ3by/oF+uvxqdw2r69ab2k9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P00338	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-372327|uniprotkb:Q53G53|uniprotkb:Q6IBM7|uniprotkb:Q6ZNV1|ensembl:ENSP00000368722|ensembl:ENSP00000395337|ensembl:ENSP00000445331|ensembl:ENSP00000499898|ensembl:ENSP00000499977|ensembl:ENSP00000500953|uniprotkb:Q9UDE8|uniprotkb:Q9UDE9|uniprotkb:D3DQY3|uniprotkb:B7Z5E3|uniprotkb:B4DKQ2|uniprotkb:F8W819	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:ldha_human(display_long)|uniprotkb:LDHA(gene name)|psi-mi:LDHA(display_short)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-59(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 19 protein(gene name synonym)|uniprotkb:PIG19(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001158886.1|ensembl:ENSG00000134333(gene)|ensembl:ENSG00000288299(gene)|ensembl:ENST00000379412(transcript)|ensembl:ENST00000422447(transcript)|ensembl:ENST00000542179(transcript)|ensembl:ENST00000671981(transcript)|ensembl:ENST00000672405(transcript)|ensembl:ENST00000673204(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045296"(cadherin binding)|go:"GO:0048569"(post-embryonic animal organ development)|go:"GO:0051287"(NAD binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|rcsb pdb:1I10|mint:P00338|rcsb pdb:4AJP|rcsb pdb:4JNK|rcsb pdb:4L4R|rcsb pdb:4L4S|rcsb pdb:4M49|rcsb pdb:4OJN|rcsb pdb:4OKN|rcsb pdb:4QO7|rcsb pdb:4QO8|rcsb pdb:4QSM|rcsb pdb:4QT0|rcsb pdb:4R68|rcsb pdb:4R69|rcsb pdb:4RLS|rcsb pdb:4ZVV|rcsb pdb:5IXS|rcsb pdb:5IXY|rcsb pdb:5W8H|rcsb pdb:5W8I|rcsb pdb:5W8J|rcsb pdb:5W8K|rcsb pdb:5W8L|rcsb pdb:5ZJD|rcsb pdb:5ZJE|rcsb pdb:5ZJF|rcsb pdb:6BAD|rcsb pdb:6BAG|rcsb pdb:6BAX|rcsb pdb:6BAZ|rcsb pdb:6BB0|rcsb pdb:6BB1|rcsb pdb:6BB2|rcsb pdb:6BB3|rcsb pdb:6MV8|rcsb pdb:6MVA|rcsb pdb:6Q0D|rcsb pdb:6SBU|rcsb pdb:6SBV|rcsb pdb:6ZZR|reactome:R-HSA-70268|rcsb pdb:6Q13|refseq:NP_001158887.1|refseq:NP_005557.1|refseq:NP_001128711.1|refseq:NP_001158888.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Zpq2lAJLPG+q2bMEru3cq7B5gCk9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024R4M0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519242	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024r4m0_human(display_long)|uniprotkb:RPS9(gene name)|psi-mi:RPS9(display_short)|uniprotkb:hCG_2009111(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045202"(synapse)|go:"GO:1990932"(5.8S rRNA binding)|refseq:NP_001004.2|refseq:NP_001308630.1|refseq:NP_001308631.1|refseq:NP_001308633.1|interpro:IPR022801|interpro:IPR005710(Ribosomal protein S4/S9, eukaryotic/archaeal)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR018079|interpro:IPR002942(RNA-binding S4)|interpro:IPR036986	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:PGNjkKMs8bMMOSOz2AQvwuCvO1A9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q99615	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-357552|ensembl:ENSP00000406463|uniprotkb:Q7Z784	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:dnjc7_human(display_long)|uniprotkb:DNAJC7(gene name)|psi-mi:DNAJC7(display_short)|uniprotkb:TPR2(gene name synonym)|uniprotkb:TTC2(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000168259(gene)|ensembl:ENST00000457167(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006457"(protein folding)|go:"GO:0016020"(membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR036869|reactome:R-HSA-3371453|refseq:NP_003306.3|refseq:XP_011523469.1|refseq:XP_011523470.1|refseq:XP_011523471.1|refseq:NP_001138238.1|refseq:XP_016880483.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:eZ1/nlVA9bOU/N3yrJ3pWrnM1P09606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P15924	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-355041|uniprotkb:O75993|uniprotkb:Q14189|uniprotkb:Q9UHN4|uniprotkb:B2RTT2|uniprotkb:D7RX09|ensembl:ENSP00000369129	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:desp_human(display_long)|uniprotkb:DSP(gene name)|psi-mi:DSP(display_short)|uniprotkb:250/210 kDa paraneoplastic pemphigus antigen(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001305963.1|refseq:NP_001008844.1|refseq:NP_004406.2|go:"GO:0014704"(intercalated disc)|go:"GO:0005916"(fascia adherens)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|ensembl:ENSG00000096696(gene)|ensembl:ENST00000379802(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:P15924|rcsb pdb:1LM5|rcsb pdb:1LM7|rcsb pdb:3R6N|rcsb pdb:5DZZ|reactome:R-HSA-351906|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9696264|reactome:R-HSA-9696273|dip:DIP-109N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:enapEqSoyTSLfPEQUAopkGpdxbo9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9Y3F4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-727414|uniprotkb:Q9UQC8|uniprotkb:Q9NTK0|uniprotkb:Q5TZT4|intact:EBI-6190807|uniprotkb:B4DNJ6|uniprotkb:B2R5S5|ensembl:ENSP00000392270	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:strap_human(display_long)|uniprotkb:UNR-interacting protein(gene name synonym)|uniprotkb:WD-40 repeat protein PT-WD(gene name synonym)|uniprotkb:MAP activator with WD repeats(gene name synonym)|uniprotkb:STRAP(gene name)|psi-mi:STRAP(display_short)|uniprotkb:MAWD(gene name synonym)|uniprotkb:UNRIP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_009109.3|ensembl:ENSG00000023734(gene)|ensembl:ENST00000419869(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:1990447"(U2 snRNP binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:Q9Y3F4|reactome:R-HSA-2173788	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:/IqZt6BHPxD3S/THUZry4+QUvCE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A0S2Z3G9	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-25633438	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a0s2z3g9_human(display_long)|uniprotkb:ACTN4(gene name)|psi-mi:ACTN4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|refseq:NP_004915.2|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:kTYezA2lEtL/AQPfCQ8BE79nzow9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q53GE7	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519235	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q53ge7_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR019734	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Ibte7aR9ilnJVV6fW1/VZF48GKM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:O75947	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-724024|ensembl:ENSP00000301587|uniprotkb:Q9H3J4|uniprotkb:B2R5L6	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:atp5h_human(display_long)|uniprotkb:ATP5PD(gene name)|psi-mi:ATP5PD(display_short)|uniprotkb:ATP synthase peripheral stalk subunit d(gene name synonym)|uniprotkb:ATP5H(gene name synonym)|uniprotkb:My032(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001003785.1|refseq:NP_006347.1|ensembl:ENSG00000167863(gene)|ensembl:ENST00000301587(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR008689(ATPase, F0 complex, subunit D, mitochondrial)|interpro:IPR036228|mint:O75947|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:GFk/w7iWIjum9BpZs8ZlPrM5kBs9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q32P28	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-396328|uniprotkb:Q96SK8|uniprotkb:Q7KZR4|uniprotkb:Q96BR8|uniprotkb:Q96SL5|uniprotkb:Q96SN3|uniprotkb:Q9H6K3|uniprotkb:Q9HC86|uniprotkb:Q9HC87|intact:EBI-2555416|ensembl:ENSP00000296388	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:p3h1_human(display_long)|uniprotkb:P3H1(gene name)|psi-mi:P3H1(display_short)|uniprotkb:GROS1(gene name synonym)|uniprotkb:Growth suppressor 1(gene name synonym)|uniprotkb:LEPRE1(gene name synonym)|uniprotkb:Leucine- and proline-enriched proteoglycan 1(gene name synonym)|uniprotkb:PSEC0109(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001139761.1|refseq:NP_001230175.1|refseq:NP_071751.3|ensembl:ENSG00000117385(gene)|ensembl:ENST00000296388(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0019797"(procollagen-proline 3-dioxygenase activity)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050821"(protein stabilization)|go:"GO:0060348"(bone development)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901874"(negative regulation of post-translational protein modification)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR039575|interpro:IPR039837|mint:Q32P28|reactome:R-HSA-1650814	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:L3euuYyawz69NXv4u6baW/ceVdU9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024R0M6	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21359196	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024r0m6_human(display_long)|uniprotkb:TIMM50(gene name)|psi-mi:TIMM50(display_short)|uniprotkb:hCG_1996416(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|refseq:NP_001001563.1|interpro:IPR004274(NLI interacting factor)|interpro:IPR036412|interpro:IPR023214|interpro:IPR027111	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:mwlscSBnVTNN0b4IwPS7EYGTS7Q9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9P2S5	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1054904|uniprotkb:Q5T0D6|uniprotkb:Q9BUH7|uniprotkb:Q9NTK7|uniprotkb:Q9NX56|ensembl:ENSP00000270708	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:wrp73_human(display_long)|uniprotkb:WRAP73(gene name)|psi-mi:WRAP73(display_short)|uniprotkb:WDR8(gene name synonym)|uniprotkb:WD repeat-containing protein 8(gene name synonym)|uniprotkb:WD repeat-containing protein antisense to TP73 gene(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_060288.3|ensembl:ENSG00000116213(gene)|ensembl:ENST00000270708(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0030030"(cell projection organization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1902440"(protein localization to mitotic spindle pole body)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1990811"(MWP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:Q9P2S5	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:H5LC0HbUA2MqmXzFg7y256KDg2U9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:D6RFN0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519218|ensembl:ENSP00000424791	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:d6rfn0_human(display_long)|uniprotkb:COPS4(gene name)|psi-mi:COPS4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000138663(gene)|ensembl:ENST00000503682(transcript)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|interpro:IPR041406	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:0EQWMPEzKr7AGX0QVXzFCV/h32o9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024RDE8	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519207	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024rde8_human(display_long)|uniprotkb:PDLIM5(gene name)|psi-mi:PDLIM5(display_short)|uniprotkb:hCG_40208(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0046872"(metal ion binding)|refseq:NP_006448.4|interpro:IPR031847|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR001781(Zinc finger, LIM-type)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:O+P5NWVWI9CTpeR/HMsDF1VErLg9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B4DR61	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21356779|ensembl:ENSP00000418493	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b4dr61_human(display_long)|uniprotkb:SEC61A1(gene name)|psi-mi:SEC61A1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000058262(gene)|ensembl:ENST00000464451(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:5ImODrF8bnJT/CSqOJb1x6kK1iY9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A8K4Z4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519197	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a8k4z4_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005840"(ribosome)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR030670|interpro:IPR043141|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR043164|interpro:IPR040637	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:52P9h0JCL9QTu2qUfO4Z0hUEbK09606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q5EC54	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-25629159	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q5ec54_human(display_long)|uniprotkb:HNRPK(gene name)|psi-mi:HNRPK(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|interpro:IPR033090|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|interpro:IPR012987(ROK, N-terminal)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:0ehV8JYmnGH1PU2mG5n2B25nwDY9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q5VVH5	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-9658404|ensembl:ENSP00000358956	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:ikbp1_human(display_long)|uniprotkb:IRAK1BP1(gene name)|psi-mi:IRAK1BP1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001010844.1|ensembl:ENSG00000146243(gene)|ensembl:ENST00000369940(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|interpro:IPR007497(Protein of unknown function DUF541)|interpro:IPR030312	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:b7cuTOTKnr/PPCp6Rp/i3zl0Hc89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q6IB11	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-10249941	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q6ib11_human(display_long)|uniprotkb:PGRMC1(gene name)|psi-mi:PGRMC1(display_short)|uniprotkb:hCG_23188(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR001199(Cytochrome b5)|refseq:NP_006658.1|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|interpro:IPR036400	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:fjKpwgj9042mPhLsvS/wu1wBEi89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024RBB7	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21355522	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024rbb7_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:hCG_2015037(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|refseq:NP_001317160.1|refseq:NP_004528.1|refseq:NP_631946.1|refseq:XP_011536695.1|refseq:XP_016874827.1|interpro:IPR037231|interpro:IPR002164("Nucleosome assembly protein (NAP)")	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q59FI9	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-10901300	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q59fi9_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR000911(Ribosomal protein L11)|interpro:IPR020783|interpro:IPR020785|interpro:IPR020784|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR036769|interpro:IPR036796	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:CtxYWqDo/ltoqrqi+krjMhWyGR89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024R1U4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21355794	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024r1u4_human(display_long)|uniprotkb:RAB5C(gene name)|psi-mi:RAB5C(display_short)|uniprotkb:hCG_2039680(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|refseq:NP_004574.2|refseq:NP_958842.1|refseq:XP_011523392.1|refseq:XP_011523393.1|interpro:IPR027417|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:sz3lmmxPJk0/IzQ9dZF0PzfNhBY9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q4LE43	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21356125	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q4le43_human(display_long)|uniprotkb:PLCG1 variant protein(gene name)|psi-mi:PLCG1 variant protein(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0035556"(intracellular signal transduction)|refseq:NP_002651.2|refseq:NP_877963.1|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR035892|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR028380|interpro:IPR035023|interpro:IPR035024|interpro:IPR017946|interpro:IPR035724|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR000980(SH2 motif)|interpro:IPR036860|interpro:IPR036028|interpro:IPR001452(Src homology-3)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:hSm8P8+axysg4eHr3vGemXJoDfI9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:O94826	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-2800236|uniprotkb:D3DN48|ensembl:ENSP00000284320	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:tom70_human(display_long)|uniprotkb:TOMM70(gene name)|psi-mi:TOMM70(display_short)|uniprotkb:KIAA0719(gene name synonym)|uniprotkb:TOM70(gene name synonym)|uniprotkb:TOMM70A(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym)|uniprotkb:Translocase of outer mitochondrial membrane protein 70(gene name synonym)|uniprotkb:Mitochondrial precursor proteins import receptor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_055635.3|ensembl:ENSG00000154174(gene)|ensembl:ENST00000284320(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O94826|rcsb pdb:7DHG|rcsb pdb:7KDT|go:"GO:0005741"(mitochondrial outer membrane)|reactome:R-HSA-168928|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-1268020	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:LtRXcptMA0w6Pv/4lksPfPJ4CYY9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q12904	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1045802|uniprotkb:Q6FG28|uniprotkb:Q96CQ9|uniprotkb:B4E1S7|uniprotkb:B3KTR2|ensembl:ENSP00000350699|ensembl:ENSP00000499850|ensembl:ENSP00000499921|ensembl:ENSP00000500025|ensembl:ENSP00000500159|ensembl:ENSP00000500170|ensembl:ENSP00000500620|ensembl:ENSP00000500668|ensembl:ENSP00000500732|ensembl:ENSP00000500794	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:aimp1_human(display_long)|uniprotkb:AIMP1(gene name)|psi-mi:AIMP1(display_short)|uniprotkb:EMAP2(gene name synonym)|uniprotkb:SCYE1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p43(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001135887.1|refseq:NP_001135888.1|refseq:NP_004748.2|ensembl:ENSG00000164022(gene)|ensembl:ENST00000358008(transcript)|ensembl:ENST00000671868(transcript)|ensembl:ENST00000671960(transcript)|ensembl:ENST00000672285(transcript)|ensembl:ENST00000672328(transcript)|ensembl:ENST00000672337(transcript)|ensembl:ENST00000672341(transcript)|ensembl:ENST00000672911(transcript)|ensembl:ENST00000673018(transcript)|ensembl:ENST00000673123(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051020"(GTPase binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0070094"(positive regulation of glucagon secretion)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q12904|rcsb pdb:1E7Z|rcsb pdb:1EUJ|rcsb pdb:1FL0|rcsb pdb:4R3Z|reactome:R-HSA-2408522|reactome:R-HSA-379716|refseq:XP_016864324.1|refseq:XP_016864325.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:UtCeSRjFyuuEHUxVF2HkG9RA55k9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P27361	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-73995|uniprotkb:B0LPG3|uniprotkb:A8CZ58|uniprotkb:Q8NHX1|ensembl:ENSP00000263025	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:mk03_human(display_long)|uniprotkb:ERT2(gene name synonym)|uniprotkb:MAP kinase isoform p44(gene name synonym)|uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym)|uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym)|uniprotkb:p44-ERK1(gene name synonym)|uniprotkb:MAPK3(gene name)|psi-mi:MAPK3(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:PRKM3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001035145.1|refseq:NP_001103361.1|refseq:NP_002737.2|dip:DIP-30985N|ensembl:ENSG00000102882(gene)|ensembl:ENST00000263025(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000657"(negative regulation of apolipoprotein binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P27361|rcsb pdb:2ZOQ|rcsb pdb:4QTB|rcsb pdb:6GES|reactome:R-HSA-110056|reactome:R-HSA-112409|reactome:R-HSA-1169408|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-73728|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:PGxmRMz0kOsJTfdn21FBiF33YwI9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A8K651	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-9512810	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a8k651_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR036561|interpro:IPR003428(Mitochondrial glycoprotein)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Jd/FA2BQ4Eah0rGwo1KdxSEGJt89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q13435	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-749111|uniprotkb:A8K485|uniprotkb:B4DT19|uniprotkb:Q7Z627|uniprotkb:Q969K1|uniprotkb:Q96CM6|uniprotkb:Q9BWD2|intact:EBI-1052093|intact:EBI-2688256|uniprotkb:Q7L4T5|ensembl:ENSP00000318861	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:sf3b2_human(display_long)|uniprotkb:SF3B2(gene name)|psi-mi:SF3B2(display_short)|uniprotkb:SAP145(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 145 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 145(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_006833.2|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006568(PSP, proline-rich)|ensembl:ENSG00000087365(gene)|ensembl:ENST00000322535(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR007180(Protein of unknown function DUF382)|rcsb pdb:2DO5|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y53|mint:Q13435|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Y9uCV2x4J5kqyxeO8iXjojkXocA9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:O95831	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-356440|uniprotkb:Q5JUZ7|uniprotkb:Q6I9X6|uniprotkb:Q9Y3I3|uniprotkb:Q9Y3I4|uniprotkb:A4QPB4|uniprotkb:B1ALN1|uniprotkb:B2RB08|intact:EBI-2561858|uniprotkb:D3DTE9|uniprotkb:Q1L6K6|uniprotkb:Q2QKE4|uniprotkb:Q1L6K4|ensembl:ENSP00000287295|uniprotkb:E9PRR0	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:aifm1_human(display_long)|uniprotkb:AIFM1(gene name)|psi-mi:AIFM1(display_short)|uniprotkb:AIF(gene name synonym)|uniprotkb:PDCD8(gene name synonym)|uniprotkb:Programmed cell death protein 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001124319.1|refseq:NP_004199.1|refseq:NP_665811.1|refseq:NP_001124318.2|rcsb pdb:5FS6|rcsb pdb:5FS7|rcsb pdb:5FS8|rcsb pdb:5FS9|rcsb pdb:5KVH|rcsb pdb:5KVI|ensembl:ENSG00000156709(gene)|ensembl:ENST00000287295(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0030182"(neuron differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0071949"(FAD binding)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1904045"(cellular response to aldosterone)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR029324|interpro:IPR036188|mint:O95831|rcsb pdb:1M6I|rcsb pdb:4BUR|rcsb pdb:4BV6|rcsb pdb:4FDC|rcsb pdb:4LII|rcsb pdb:5FMH|dip:DIP-32975N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:tAY+mPStfDGbCN4OpvHF4ljQ69I9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A8K8U1	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21354847	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a8k8u1_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0010265"(SCF complex assembly)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039852|interpro:IPR013932("TATA-binding protein interacting (TIP20)")	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:CmiPJxiMHyxEvc88Pnsq49Zj5D49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P42575	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-520342|ensembl:ENSP00000312664|uniprotkb:P42576|uniprotkb:D3DXD6|uniprotkb:Q59F21|uniprotkb:Q7KZL6|uniprotkb:Q86UJ3|uniprotkb:Q9BUP7|uniprotkb:Q9BZK9|uniprotkb:A8K5F9|uniprotkb:E9PDN0|uniprotkb:Q9BZL0	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:casp2_human(display_long)|uniprotkb:Protease ICH-1(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 2(gene name synonym)|uniprotkb:CASP2(gene name)|psi-mi:CASP2(display_short)|uniprotkb:ICH1(gene name synonym)|uniprotkb:NEDD2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000106144(gene)|ensembl:ENST00000310447(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0003407"(neural retina development)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR035702|rcsb pdb:1PYO|rcsb pdb:2P2C|rcsb pdb:3R5J|rcsb pdb:3R6G|rcsb pdb:3R6L|rcsb pdb:3R7B|rcsb pdb:3R7N|refseq:NP_001215.1|refseq:NP_116764.2|refseq:NP_116765.2|rcsb pdb:3R7S|rcsb pdb:3RJM|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y8B|rcsb pdb:6Y8D|reactome:R-HSA-168638|reactome:R-HSA-205025|reactome:R-HSA-6803207	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:3WFvmDoYbW3J84Yd9RVGAOcR8ig9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:E9KL48	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21352904	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:e9kl48_human(display_long)|uniprotkb:GLUD1(gene name)|psi-mi:GLUD1(display_short)|uniprotkb:hCG_1993805(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0004354"("glutamate dehydrogenase (NADP+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0006520"(cellular amino acid metabolic process)|refseq:NP_005262.1|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR033524|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR036291|interpro:IPR033922	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:rWYi7otiOLlUvfEl7Vy6ELkY+BM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B3KNB4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519190	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b3knb4_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR036815|interpro:IPR023410	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:GxUS2K8S0Ie4O31GGS2Bfg1u7yk9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q7Z3D7	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-25629215	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q7z3d7_human(display_long)|uniprotkb:DKFZp686E2459(gene name)|psi-mi:DKFZp686E2459(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|refseq:NP_001191395.1|refseq:NP_001191397.1|interpro:IPR000467(D111/G-patch)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR041591|interpro:IPR035979|interpro:IPR033095|interpro:IPR035618|interpro:IPR034992|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR036443	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:BVb+bgfJ1dJB+UQafCdZ7sAcrP09606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P23396	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P25705	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-351437|uniprotkb:Q53XX6|uniprotkb:Q8IXV2|uniprotkb:Q96FB4|uniprotkb:Q96HW2|uniprotkb:Q96IR6|uniprotkb:Q9BTV8|intact:EBI-11032691|uniprotkb:A8K092|uniprotkb:B4DY56|uniprotkb:K7ENP3|ensembl:ENSP00000282050|ensembl:ENSP00000381736	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:atpa_human(display_long)|uniprotkb:ATP5F1A(gene name)|psi-mi:ATP5F1A(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5A1(gene name synonym)|uniprotkb:ATP5AL2(gene name synonym)|uniprotkb:ATPM(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001244263.1|refseq:NP_001001937.1|refseq:NP_004037.1|refseq:NP_001001935.1|refseq:NP_001244264.1|dip:DIP-32871N|ensembl:ENSG00000152234(gene)|ensembl:ENST00000282050(transcript)|ensembl:ENST00000398752(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:P25705|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Sy/Ii5ea+ilCKGBnIEMn133Vogc9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A0S2Z3L2	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21352075	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a0s2z3l2_human(display_long)|uniprotkb:ATP2A2(gene name)|psi-mi:ATP2A2(display_short)|uniprotkb:hCG_39049(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0006996"(organelle organization)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0097470"(ribbon synapse)|interpro:IPR044492|refseq:NP_733765.1|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR023299|interpro:IPR018303|interpro:IPR023298|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR036412|interpro:IPR023214|interpro:IPR005782(Calcium ATPase)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:QlJZW2fprLYahKUrHDOVs28kA2w9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A0D9SF53	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21358583|ensembl:ENSP00000486306	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a0d9sf53_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000215301(gene)|ensembl:ENST00000625837(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016787"(hydrolase activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:sSayOB2oSSFX94pRbYkBv+vcAlg9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q14008	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-310585|uniprotkb:Q0VAX8|uniprotkb:Q14668|uniprotkb:Q05D70|uniprotkb:Q0VAX7|uniprotkb:Q2TA89|uniprotkb:Q6NSH4|intact:EBI-28968667|ensembl:ENSP00000432768	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:ckap5_human(display_long)|uniprotkb:CKAP5(gene name)|psi-mi:CKAP5(display_short)|uniprotkb:KIAA0097(gene name synonym)|uniprotkb:Colonic and hepatic tumor overexpressed gene protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENST00000312055|ensembl:ENSP00000310227|ensembl:ENST00000354558|ensembl:ENSP00000346566|ensembl:ENSP00000432768|refseq:NP_001008938.1|refseq:NP_055571.2|ensembl:ENSG00000175216(gene)|ensembl:ENST00000529230(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0050658"(RNA transport)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0061863"(microtubule plus end polymerase)|go:"GO:0090063"(positive regulation of microtubule nucleation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024395|interpro:IPR034085|mint:Q14008|rcsb pdb:4QMI|rcsb pdb:4QMJ|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:3bgwyNEucxXwXdbxbJkJ07PC90w9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P26373	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-356849|uniprotkb:Q3KQT8|uniprotkb:Q9BPX0|uniprotkb:Q567Q8|uniprotkb:B4DLX3|uniprotkb:F5H1S2|ensembl:ENSP00000307889|ensembl:ENSP00000376811|ensembl:ENSP00000455009	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rl13_human(display_long)|uniprotkb:RPL13(gene name)|psi-mi:RPL13(display_short)|uniprotkb:BBC1(gene name synonym)|uniprotkb:Breast basic conserved protein 1(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL13(gene name synonym)|uniprotkb:OK/SW-cl.46(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_000968.2|refseq:NP_150254.1|refseq:NP_001230059.1|refseq:NP_001230060.1|ensembl:ENSG00000167526(gene)|ensembl:ENST00000311528(transcript)|ensembl:ENST00000393099(transcript)|ensembl:ENST00000567815(transcript)|go:"GO:0001824"(blastocyst development)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0060348"(bone development)|interpro:IPR001380(Ribosomal protein L13e)|interpro:IPR018256|mint:P26373|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-192823	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:2SZ+AEe41Ystwj9t9I0Z1cZ5GQ49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P07814	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-355315|uniprotkb:Q5H9S5|uniprotkb:Q6PD57|uniprotkb:Q86X73|uniprotkb:A0AVA9|uniprotkb:Q05BP6|uniprotkb:Q05DF8|uniprotkb:Q5DSM1|ensembl:ENSP00000355890|uniprotkb:B9EGH3	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:syep_human(display_long)|uniprotkb:EPRS1(gene name)|psi-mi:EPRS1(display_short)|uniprotkb:Bifunctional aminoacyl-tRNA synthetase(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 32 protein(gene name synonym)|uniprotkb:EPRS(gene name synonym)|uniprotkb:GLNS(gene name synonym)|uniprotkb:Glutamatyl-prolyl-tRNA synthetase(gene name synonym)|uniprotkb:PARS(gene name synonym)|uniprotkb:QARS(gene name synonym)|uniprotkb:QPRS(gene name synonym)|uniprotkb:PIG32(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_004437.2|ensembl:ENSG00000136628(gene)|ensembl:ENST00000366923(transcript)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0140212"(regulation of long-chain fatty acid import into cell)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000738(WHEP-TRS)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004499(Prolyl-tRNA synthetase, class IIa, prokaryotic-type)|interpro:IPR004526(Glutamyl-tRNA synthetase, class Ic, archaeal/eukaryotic cytosolic)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR016061(Prolyl-tRNA synthetase, class II, C-terminal)|interpro:IPR017449(Prolyl-tRNA synthetase, class II)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR033721|interpro:IPR036282|interpro:IPR036621|mint:P07814|rcsb pdb:1FYJ|rcsb pdb:4HVC|rcsb pdb:4K86|rcsb pdb:4K87|rcsb pdb:4K88|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5BMU|rcsb pdb:5V58|rcsb pdb:5VAD|rcsb pdb:5Y6L|rcsb pdb:6IY6|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-6782315|dip:DIP-40825N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:67nL6JkhNTSttOucQt3mLRQZeLY9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:J3KPS3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519172|ensembl:ENSP00000378661	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:j3kps3_human(display_long)|uniprotkb:ALDOA(gene name)|psi-mi:ALDOA(display_short)|uniprotkb:hCG_1811258(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000149925(gene)|ensembl:ENST00000395240(transcript)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006096"(glycolytic process)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:L5CC8CuAOvk5mV/ejSmWdLVPkyk9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q59G24	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21351762	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q59g24_human(display_long)|uniprotkb:SUB1 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR003173(Transcriptional coactivator p15)|interpro:IPR009044(ssDNA-binding transcriptional regulator)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:rdJArX0zFTT2n/k/WsoH3S6SnmM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B3KWV6	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519162	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b3kwv6_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005737"(cytoplasm)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|interpro:IPR008081(Cytoplasmic FMR1-interacting)|interpro:IPR009828(Protein of unknown function DUF1394)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:fJmIZ5wBdz0SqEM9f+wDNgfb0jU9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:D3DQR0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519149	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:d3dqr0_human(display_long)|uniprotkb:PACSIN3(gene name)|psi-mi:PACSIN3(display_short)|uniprotkb:hCG_25176(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0016301"(kinase activity)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR027267|interpro:IPR031160|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR028523|interpro:IPR036028|interpro:IPR001452(Src homology-3)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:WWxFdt+zTvN5+uIqnQ+Qmx76BXk9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q15370	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-301238|ensembl:ENSP00000386652|uniprotkb:B7WPD3	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:elob_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:TCEB2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000103363(gene)|ensembl:ENST00000409906(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:Q15370|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2JZ3|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:4WQO|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:6SIS|refseq:NP_009039.1|refseq:NP_996896.1|dip:DIP-29570N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:apX4QFpDC4Dz3MAs7tQ8+XFHx6I9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B3KM36	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21357125	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b3km36_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR037689|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:NUC+SbwmKXoYlAKgILPypXOOrmw9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q96F07	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-2433893|uniprotkb:A6NLT2|uniprotkb:Q53EN5|uniprotkb:Q9NTK4|uniprotkb:Q9ULQ2|uniprotkb:Q9UN29|uniprotkb:D3DQJ3|ensembl:ENSP00000479719	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:cyfp2_human(display_long)|uniprotkb:CYFIP2(gene name)|psi-mi:CYFIP2(display_short)|uniprotkb:KIAA1168(gene name synonym)|uniprotkb:PIR121(gene name synonym)|uniprotkb:p53-inducible protein 121(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:XP_011532818.1|refseq:NP_001032410.1|refseq:NP_055191.2|refseq:NP_001278650.1|refseq:NP_001278651.1|refseq:XP_016864830.1|ensembl:ENSG00000055163(gene)|ensembl:ENST00000616178(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0031209"(SCAR complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0097484"(dendrite extension)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR008081(Cytoplasmic FMR1-interacting)|interpro:IPR009828(Protein of unknown function DUF1394)|mint:Q96F07|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9664422	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:EjzXClJ8fIqHFNSPrDRAjLT8bOM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024R1Z6	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519135	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024r1z6_human(display_long)|uniprotkb:VAT1(gene name)|psi-mi:VAT1(display_short)|uniprotkb:hCG_16957(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016491"(oxidoreductase activity)|refseq:NP_006364.2|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR011032(GroES-like)|interpro:IPR036291|interpro:IPR020843|interpro:IPR002364(Quinone oxidoreductase/zeta-crystallin, conserved site)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:CaICWyJ+h3ry4itndQodektQFQo9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P61962	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B2RBR9	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-9512631	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b2rbr9_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR000225(Armadillo)|interpro:IPR040122|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:3AWYgPEZ95Z9u8iCMflQ3CEGoyk9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P27824	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P05023	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|ensembl:ENSP00000295598|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|intact:EBI-10963133	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|ensembl:ENSG00000163399(gene)|ensembl:ENST00000295598(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903416"(response to glycoside)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P05023|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q14257	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-356710|uniprotkb:A8MTG6|uniprotkb:Q53XN8|ensembl:ENSP00000378349|uniprotkb:F8WCY5	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rcn2_human(display_long)|uniprotkb:RCN2(gene name)|psi-mi:RCN2(display_short)|uniprotkb:ERC55(gene name synonym)|uniprotkb:Calcium-binding protein ERC-55(gene name synonym)|uniprotkb:E6-binding protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_002893.1|ensembl:ENST00000394885(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENSG00000117906(gene)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q14257|refseq:NP_001258766.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:99ru/7eYUvZ5xdb+x4inbib3PP89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q14847	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-742828|uniprotkb:Q96ED2|uniprotkb:Q96IG0|ensembl:ENSP00000325240|ensembl:ENSP00000392853|uniprotkb:B4DGQ0	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:lasp1_human(display_long)|uniprotkb:Metastatic lymph node gene 50 protein(gene name synonym)|uniprotkb:LASP1(gene name)|psi-mi:LASP1(display_short)|uniprotkb:MLN50(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_006139.1|refseq:NP_001258537.1|ensembl:ENSG00000002834(gene)|ensembl:ENST00000318008(transcript)|ensembl:ENST00000435347(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006811"(ion transport)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR035630|interpro:IPR036028|mint:Q14847|rcsb pdb:3I35	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Oa+FdJXeQhahYTqVrHYk6yBrUWI9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q8WVX7	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21351292	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q8wvx7_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR036388|interpro:IPR001266(Ribosomal protein S19e)|interpro:IPR018277|interpro:IPR036390	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:4M6sHl8NabdqR/Vjf+DUcWsbwd89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:H3BS72	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-25629274|ensembl:ENSP00000456568	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:h3bs72_human(display_long)|uniprotkb:HACD3(gene name)|psi-mi:HACD3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000074696(gene)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0102158"(very-long-chain 3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0102343"(3-hydroxy-arachidoyl-CoA dehydratase activity)|go:"GO:0102344"(3-hydroxy-behenoyl-CoA dehydratase activity)|go:"GO:0102345"(3-hydroxy-lignoceroyl-CoA dehydratase activity)|interpro:IPR007052(CS domain)|interpro:IPR007482(Protein-tyrosine phosphatase-like, PTPLA)|interpro:IPR008978(HSP20-like chaperone)|ensembl:ENST00000565299(transcript)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:X7uSCZI6uzx+LCbGO2UlaZK3lM09606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q15365	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_006187.2|dip:DIP-38136N|ensembl:ENSG00000169564(gene)|ensembl:ENST00000303577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q53HV2	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-11602444	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q53hv2_human(display_long)|uniprotkb:CCT-eta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR027410|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:FaHsvqPLiG2q17loJArr1VPe8Dk9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A140VJT0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519124	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a140vjt0_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0098978"(glutamatergic synapse)|refseq:NP_002708.1|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR018067|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR036322	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:evS6klM2alZXtMthVsshKkrNgiA9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024RBF6	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-25604984	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024rbf6_human(display_long)|uniprotkb:hCG_26523(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|interpro:IPR005824(KOW)|interpro:IPR041988|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR005756(Ribosomal protein L26, eukaryotic/archaeal)|interpro:IPR008991(Translation protein SH3-like)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:jwlWRQrUOCA05pZtZ7yPgfxSKAg9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P61026	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-726075|uniprotkb:O88386|uniprotkb:Q6IA52|uniprotkb:Q9D7X6|uniprotkb:Q9H0T3|uniprotkb:D6W538|ensembl:ENSP00000264710	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rab10_human(display_long)|uniprotkb:RAB10(gene name)|psi-mi:RAB10(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_057215.3|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031489"(myosin V binding)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0097051"(establishment of protein localization to endoplasmic reticulum membrane)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:5LPN|rcsb pdb:5SZJ|reactome:R-HSA-1445148|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000084733(gene)|ensembl:ENST00000264710(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:ZbfLtWtXl3z6/MYyhiZp6P1Y5tE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:E5KNY5	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21356362	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:e5kny5_human(display_long)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:hCG_16810(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|refseq:NP_573566.2|interpro:IPR033490|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR033443|interpro:IPR011990(Tetratricopeptide-like helical)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B2RDD7	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519110	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b2rdd7_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)|interpro:IPR025799|interpro:IPR007857(Skb1 methyltransferase)|interpro:IPR035075|interpro:IPR035248|interpro:IPR035247|interpro:IPR029063	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:NDHYD711pGTG3+UtSy7gSd/9gZE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:J3QQ67	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21358476|ensembl:ENSP00000084795	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:j3qq67_human(display_long)|uniprotkb:RPL18(gene name)|psi-mi:RPL18(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000063177(gene)|ensembl:ENST00000084795(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR000039(Ribosomal protein L18e)|interpro:IPR021131|interpro:IPR021132|interpro:IPR036227	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:J/rWpVY/Cdx0qnUKuwTh1ZPc91g9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q15056	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-748492|uniprotkb:A8K3R1|uniprotkb:D3DXF6|uniprotkb:D3DXF8|ensembl:ENSP00000265753	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:if4h_human(display_long)|uniprotkb:Williams-Beuren syndrome chromosomal region 1 protein(gene name synonym)|uniprotkb:EIF4H(gene name)|psi-mi:EIF4H(display_short)|uniprotkb:WBSCR1(gene name synonym)|uniprotkb:KIAA0038(gene name synonym)|uniprotkb:WSCR1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_071496.1|refseq:NP_114381.1|ensembl:ENSG00000106682(gene)|ensembl:ENST00000265753(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0019953"(sexual reproduction)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034057"(RNA strand-exchange activity)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0097010"(eukaryotic translation initiation factor 4F complex assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034229|interpro:IPR035979|mint:Q15056|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:dNPoAzwFD5lFwCMnRl0cbXM3j8s9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9Y4G6	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1220811|uniprotkb:A6NLB8|ensembl:ENSP00000453508	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:tln2_human(display_long)|uniprotkb:TLN2(gene name)|psi-mi:TLN2(display_short)|uniprotkb:KIAA0320(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_055874.2|refseq:XP_016878157.1|dip:DIP-17039N|ensembl:ENSG00000171914(gene)|ensembl:ENST00000561311(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045202"(synapse)|go:"GO:0051015"(actin filament binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR002558(I/LWEQ)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR015009(Vinculin Binding Site)|interpro:IPR015224(Talin, central)|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR032425|interpro:IPR035963|interpro:IPR035964|interpro:IPR036476|interpro:IPR036723|interpro:IPR037438|mint:Q9Y4G6|rcsb pdb:6U4K	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:/vkImDHugUJnyPtaJs/XfDyhXYo9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P62424	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-354172|uniprotkb:P11518|uniprotkb:Q5T8U4|ensembl:ENSP00000361076|ensembl:ENSP00000487443	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rl7a_human(display_long)|uniprotkb:RPL7A(gene name)|psi-mi:RPL7A(display_short)|uniprotkb:SURF-3(gene name synonym)|uniprotkb:SURF3(gene name synonym)|uniprotkb:Surfeit locus protein 3(gene name synonym)|uniprotkb:PLA-X polypeptide(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_000963.1|dip:DIP-31502N|ensembl:ENSG00000148303(gene)|ensembl:ENSG00000280858(gene)|ensembl:ENST00000323345(transcript)|ensembl:ENST00000630979(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR001921(Ribosomal protein L7A)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P62424|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|go:"GO:0005634"(nucleus)|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:shPtLmc+oabT/rSwho+tP1iJy4k9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A090N7U0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519082	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a090n7u0_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short)|uniprotkb:hCG_16546(orf name)|uniprotkb:tcag7.516(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|refseq:NP_003583.2|refseq:XP_005250117.1|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR036317|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|interpro:IPR036388|interpro:IPR036390	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P23526	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1053240|uniprotkb:Q96A36|ensembl:ENSP00000217426|uniprotkb:B3KUN3|uniprotkb:F5H737|uniprotkb:A8K307|uniprotkb:E1P5P2	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:sahh_human(display_long)|uniprotkb:S-adenosyl-L-homocysteine hydrolase(gene name synonym)|uniprotkb:AHCY(gene name)|psi-mi:AHCY(display_short)|uniprotkb:SAHH(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_000678.1|refseq:NP_001155238.1|ensembl:ENSG00000101444(gene)|ensembl:ENST00000217426(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002439"(chronic inflammatory response to antigenic stimulus)|go:"GO:0004013"(adenosylhomocysteinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0019510"(S-adenosylhomocysteine catabolic process)|go:"GO:0030554"(adenyl nucleotide binding)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0042470"(melanosome)|go:"GO:0042745"(circadian sleep/wake cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|mint:P23526|rcsb pdb:1A7A|rcsb pdb:1LI4|refseq:XP_011526961.1|refseq:XP_005260374.1|refseq:NP_001309013.1|refseq:NP_001309014.1|rcsb pdb:3NJ4|rcsb pdb:4PFJ|rcsb pdb:4PGF|rcsb pdb:4YVF|rcsb pdb:5W49|rcsb pdb:5W4B|reactome:R-HSA-156581|reactome:R-HSA-1614635|reactome:R-HSA-2408508|reactome:R-HSA-5578997|refseq:XP_016883197.1|refseq:XP_016883198.1|dip:DIP-50557N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:+y7rwgw9EIMaVrkt4/9kbZM44sg9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9Y6Y0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-715774|uniprotkb:Q1G4T6|uniprotkb:Q1G4T7|uniprotkb:Q5TF75|uniprotkb:Q6NW38|uniprotkb:Q7LCG2|uniprotkb:Q9NZX0|uniprotkb:Q9Y480|uniprotkb:A8K8R6|ensembl:ENSP00000356468	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:ns1bp_human(display_long)|uniprotkb:Aryl hydrocarbon receptor-associated protein 3(gene name synonym)|uniprotkb:IVNS1ABP(gene name)|psi-mi:IVNS1ABP(display_short)|uniprotkb:ARA3(gene name synonym)|uniprotkb:FLARA3(gene name synonym)|uniprotkb:KIAA0850(gene name synonym)|uniprotkb:NS1(gene name synonym)|uniprotkb:NS1BP(gene name synonym)|uniprotkb:HSPC068(orf name)|uniprotkb:KLHL39(gene name synonym)|uniprotkb:Kelch-like protein 39(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_006460.2|ensembl:ENSG00000116679(gene)|ensembl:ENST00000367498(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008380"(RNA splicing)|go:"GO:0009615"(response to virus)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017096(Kelch-like protein, gigaxonin)|rcsb pdb:5YY8|rcsb pdb:6N34|rcsb pdb:6N3H|interpro:IPR015915(Kelch-type beta propeller)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:27jzoex7cmDEgCPCpPMGbZ0pj489606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B7Z6S9	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-9395055	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b7z6s9_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR033452|interpro:IPR033453|interpro:IPR001139(Glycoside hydrolase, family 30)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:NP_001005741.1|refseq:NP_001005742.1|refseq:NP_001165282.1|go:"GO:0004348"(glucosylceramidase activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0016757"(glycosyltransferase activity)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:rgpGrr+jQVTQt1c65PSARasSJ9Y9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P55072	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9NX46	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-718580|uniprotkb:Q53G94|uniprotkb:Q6IAB8|uniprotkb:Q9BY47|ensembl:ENSP00000362273	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:adprs_human(display_long)|uniprotkb:ADPRS(gene name)|psi-mi:ADPRS(display_short)|uniprotkb:ADP-ribosylhydrolase 3(gene name synonym)|uniprotkb:ADPRHL2(gene name synonym)|uniprotkb:ARH3(gene name synonym)|uniprotkb:O-acetyl-ADP-ribose deacetylase ARH3(gene name synonym)|uniprotkb:"Poly(ADP-ribose) glycohydrolase ARH3"(gene name synonym)|uniprotkb:[Protein ADP-ribosylarginine] hydrolase-like protein 2(gene name synonym)|uniprotkb:[Protein ADP-ribosylserine] hydrolase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_060295.1|ensembl:ENSG00000116863(gene)|ensembl:ENST00000373178(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0004649"("poly(ADP-ribose) glycohydrolase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006281"(DNA repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0016604"(nuclear body)|go:"GO:0061463"(O-acetyl-ADP-ribose deacetylase activity)|go:"GO:0071451"(cellular response to superoxide)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140290"(peptidyl-serine ADP-deribosylation)|go:"GO:0140292"(ADP-ribosylserine hydrolase activity)|interpro:IPR005502(ADP-ribosylation/Crystallin J1)|interpro:IPR036705|rcsb pdb:2FOZ|rcsb pdb:2FP0|rcsb pdb:2G4K|rcsb pdb:5ZQY|rcsb pdb:6D36|rcsb pdb:6D3A|rcsb pdb:7AKR|rcsb pdb:7AKS|rcsb pdb:7ARW|rcsb pdb:7L9F|rcsb pdb:7L9H|rcsb pdb:7L9I|reactome:R-HSA-110362	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:N+MAzZodk/r6pLZPSTbGiwU4AXE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A4D1Z4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519065	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a4d1z4_human(display_long)|uniprotkb:KIAA0415(gene name)|psi-mi:KIAA0415(display_short)|uniprotkb:tcag7.1310(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044599"(AP-5 adaptor complex)|go:"GO:0005634"(nucleus)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR028222|interpro:IPR011989(Armadillo-like helical)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:uzuMn4i0VE5LBgsj5fHqVFNUuik9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024R814	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21357548	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024r814_human(display_long)|uniprotkb:RPL7(gene name)|psi-mi:RPL7(display_short)|uniprotkb:hCG_1983988(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR036919|interpro:IPR018038|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR039699|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR035808	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:jRqUc/PiKVmhtvdGHp7yGE7/0kM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9NTJ3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-356173|uniprotkb:A6NLT9|uniprotkb:O95752|uniprotkb:Q8NDL4|uniprotkb:Q9UNT9|uniprotkb:D3DNL8|ensembl:ENSP00000341382|ensembl:ENSP00000349961	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:smc4_human(display_long)|uniprotkb:SMC4(gene name)|psi-mi:SMC4(display_short)|uniprotkb:CAPC(gene name synonym)|uniprotkb:SMC4L1(gene name synonym)|uniprotkb:Chromosome-associated polypeptide C(gene name synonym)|uniprotkb:XCAP-C homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001002800.1|refseq:NP_005487.3|refseq:XP_011510613.1|refseq:NP_001275682.1|ensembl:ENSG00000113810(gene)|ensembl:ENST00000344722(transcript)|ensembl:ENST00000357388(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016607"(nuclear speck)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051383"(kinetochore organization)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041738|mint:Q9NTJ3|rcsb pdb:4U4P|reactome:R-HSA-2299718|reactome:R-HSA-2514853|dip:DIP-32946N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:+2lnTSgTXZwRawJ/ASBRa6EDgv09606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P17987	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:G9K388	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-25624296	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:g9k388_human(display_long)|uniprotkb:YWHAE/FAM22A fusion(gene name)|psi-mi:YWHAE/FAM22A fusion(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR036815|interpro:IPR023410|interpro:IPR024309	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:aivk4jIQOn4gwbJYv8Hu/Tll91U9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q05639	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-354943|ensembl:ENSP00000217182|uniprotkb:P54266|uniprotkb:Q0VGC7|uniprotkb:B5BUF3|uniprotkb:E1P5J1	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:ef1a2_human(display_long)|uniprotkb:EEF1A2(gene name)|psi-mi:EEF1A2(display_short)|uniprotkb:EEF1AL(gene name synonym)|uniprotkb:STN(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-2(gene name synonym)|uniprotkb:Statin-S1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000101210(gene)|ensembl:ENST00000217182(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0090218"(positive regulation of lipid kinase activity)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:Q05639|rcsb pdb:3C5J|reactome:R-HSA-156842|refseq:NP_001949.1|dip:DIP-40060N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:vFXfcSRokxKo5RW0tRE1qEK0NKw9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A4D0V4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519047	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a4d0v4_human(display_long)|uniprotkb:CAPZA2(gene name)|psi-mi:CAPZA2(display_short)|uniprotkb:hCG_37884(orf name)|uniprotkb:tcag7.31(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003779"(actin binding)|go:"GO:0005903"(brush border)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0051016"(barbed-end actin filament capping)|refseq:NP_006127.1|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|interpro:IPR017865	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:7+0w8fJ0OowIwAC7/tdNqiGSepc9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B4DMN1	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21352986	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b4dmn1_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|interpro:IPR027417|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:B2zPJ911ZqxRkUYsZI+Yl3q9DjQ9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:G3V5T9	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21359735|ensembl:ENSP00000452514	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:g3v5t9_human(display_long)|uniprotkb:CDK2(gene name)|psi-mi:CDK2(display_short)|uniprotkb:hCG_24992(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR011009(Protein kinase-like)|ensembl:ENSG00000123374(gene)|ensembl:ENST00000553376(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:XP_011536034.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:d4VoQ1dPcCCRlolew/3lJzyBVL89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P31040	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1057265|uniprotkb:Q16395|uniprotkb:Q9UMY5|uniprotkb:B4DJ60|uniprotkb:E9PBJ5|uniprotkb:Q59GW8|uniprotkb:Q8IW48|uniprotkb:A8K5J6|ensembl:ENSP00000264932	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:sdha_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short)|uniprotkb:SDH2(gene name synonym)|uniprotkb:SDHF(gene name synonym)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001281261.1|refseq:NP_004159.2|ensembl:ENSG00000073578(gene)|ensembl:ENST00000264932(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|rcsb pdb:6VAX|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-45851N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:NfhgIzmcsvfPG1BP7tHcna+jTIY9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P04843	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-355963|ensembl:ENSP00000296255|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000163902(gene)|ensembl:ENST00000296255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|go:"GO:0006464"(cellular protein modification process)|refseq:NP_002941.1|dip:DIP-38152N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P27708	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-355504|uniprotkb:Q6P0Q0|uniprotkb:D6W552|ensembl:ENSP00000264705|uniprotkb:Q96CK3	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:pyr1_human(display_long)|uniprotkb:CAD(gene name)|psi-mi:CAD(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_004332.2|ensembl:ENSG00000084774(gene)|ensembl:ENST00000264705(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070335"(aspartate binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:P27708|go:"GO:0016020"(membrane)|rcsb pdb:4BY3|rcsb pdb:4C6B|rcsb pdb:4C6C|rcsb pdb:4C6D|rcsb pdb:4C6E|rcsb pdb:4C6F|rcsb pdb:4C6I|rcsb pdb:4C6J|rcsb pdb:4C6K|rcsb pdb:4C6L|rcsb pdb:4C6M|rcsb pdb:4C6N|rcsb pdb:4C6O|rcsb pdb:4C6P|rcsb pdb:4C6Q|rcsb pdb:5G1N|rcsb pdb:5G1O|rcsb pdb:5G1P|rcsb pdb:5YNZ|rcsb pdb:6HFD|rcsb pdb:6HFE|rcsb pdb:6HFF|rcsb pdb:6HFH|rcsb pdb:6HFI|rcsb pdb:6HFJ|rcsb pdb:6HFK|rcsb pdb:6HFL|rcsb pdb:6HFP|rcsb pdb:6HFQ|rcsb pdb:6HFR|rcsb pdb:6HFS|rcsb pdb:6HFU|rcsb pdb:6HG1|reactome:R-HSA-500753|rcsb pdb:6HFN|refseq:NP_001293008.1|dip:DIP-39484N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:m5iR4BQz6t2dbQxtP1MARVW0LAw9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q5H9N4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-2556923	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q5h9n4_human(display_long)|uniprotkb:DKFZp686L20222(gene name)|psi-mi:DKFZp686L20222(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:0rKGW/sNH8XYSz3Sz5Ww1eCrqwI9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P05387	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-352813|ensembl:ENSP00000322419|ensembl:ENSP00000431240|uniprotkb:Q6FG96	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rla2_human(display_long)|uniprotkb:RPLP2(gene name)|psi-mi:RPLP2(display_short)|uniprotkb:RPP2(gene name synonym)|uniprotkb:D11S2243E(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-44(gene name synonym)|uniprotkb:Large ribosomal subunit protein P2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000177600(gene)|ensembl:ENST00000321153(transcript)|ensembl:ENST00000530797(transcript)|go:"GO:0002182"(cytoplasmic translational elongation)|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|mint:P05387|rcsb pdb:1S4J|rcsb pdb:2JDL|rcsb pdb:2LBF|rcsb pdb:2W1O|rcsb pdb:4BEH|rcsb pdb:4V6X|rcsb pdb:5DDZ|rcsb pdb:5GU4|go:"GO:0003735"(structural constituent of ribosome)|reactome:R-HSA-156827|reactome:R-HSA-156902|refseq:NP_000995.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:IBI+x82JJYg66MPhGKw1/pI/bQA9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P02533	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-702178|uniprotkb:Q14715|uniprotkb:Q53XY3|uniprotkb:Q9BUE3|uniprotkb:Q9UBN2|uniprotkb:Q9UBN3|uniprotkb:Q9UCY4|ensembl:ENSP00000167586	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:k1c14_human(display_long)|uniprotkb:Cytokeratin-14(gene name synonym)|uniprotkb:KRT14(gene name)|psi-mi:KRT14(display_short)|uniprotkb:Keratin-14(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_000517.2|dip:DIP-33874N|ensembl:ENSG00000186847(gene)|ensembl:ENST00000167586(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007568"(aging)|go:"GO:0008544"(epidermis development)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042633"(hair cycle)|go:"GO:0045095"(keratin filament)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045178"(basal part of cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990254"(keratin filament binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P02533|rcsb pdb:3TNU|rcsb pdb:6JFV|reactome:R-HSA-446107|reactome:R-HSA-6805567|reactome:R-HSA-6809371	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:IO1k6S8FB65jQr4GNwhKuxZ1ohg9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:R9S3C3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519036	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:r9s3c3_human(display_long)|uniprotkb:p14ARF(gene name)|psi-mi:p14ARF(display_short)|uniprotkb:p16INK4a fusion(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR036770|interpro:IPR010868(Cyclin-dependent kinase inhibitor 2a p19Arf, N-terminal)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:TjjB57VyQ+/fyrrGoolf3Yiz0F49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P51149	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062|ensembl:ENSP00000501618|ensembl:ENSP00000502000|ensembl:ENSP00000502088|ensembl:ENSP00000502486	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_004628.4|ensembl:ENSG00000075785(gene)|ensembl:ENST00000265062(transcript)|ensembl:ENST00000674589(transcript)|ensembl:ENST00000675342(transcript)|ensembl:ENST00000675497(transcript)|ensembl:ENST00000676214(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0019076"(viral release from host cell)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032419"(extrinsic component of lysosome membrane)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090382"(phagosome maturation)|go:"GO:0090383"(phagosome acidification)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1902586"(obsolete multi-organism intercellular transport)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905394"(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:6IYB|rcsb pdb:6WCW|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|rcsb pdb:3LAW|dip:DIP-39879N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:D6REE5	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26519021|ensembl:ENSP00000425008	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:d6ree5_human(display_long)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000204628(gene)|ensembl:ENST00000512968(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:VNa+886xt9pCT+nMozWiiRBHsoY9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P30041	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-2255129|uniprotkb:A8JZY7|uniprotkb:P32077|uniprotkb:Q5TAH4|uniprotkb:Q5ZEZ8|ensembl:ENSP00000342026	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:prdx6_human(display_long)|uniprotkb:PRDX6(gene name)|psi-mi:PRDX6(display_short)|uniprotkb:AOP2(gene name synonym)|uniprotkb:KIAA0106(gene name synonym)|uniprotkb:Antioxidant protein 2(gene name synonym)|uniprotkb:1-Cys peroxiredoxin(gene name synonym)|uniprotkb:Acidic calcium-independent phospholipase A2(gene name synonym)|uniprotkb:Non-selenium glutathione peroxidase(gene name synonym)|uniprotkb:24 kDa protein(gene name synonym)|uniprotkb:Liver 2D page spot 40(gene name synonym)|uniprotkb:Red blood cells page spot 12(gene name synonym)|uniprotkb:Glutathione-dependent peroxiredoxin(gene name synonym)|uniprotkb:Lysophosphatidylcholine acyltransferase 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_004896.1|ensembl:ENSG00000117592(gene)|ensembl:ENST00000340385(transcript)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0102567"|go:"GO:0102568"|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|rcsb pdb:1PRX|rcsb pdb:5B6M|rcsb pdb:5B6N|reactome:R-HSA-3299685|reactome:R-HSA-6798695|go:"GO:0042744"(hydrogen peroxide catabolic process)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:ZMsHgrAJf0VJiCELzo+zSi8Ji+49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:O14654	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-356594|ensembl:ENSP00000505547	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q6FGM0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-10173690	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q6fgm0_human(display_long)|uniprotkb:SH3GL1(gene name)|psi-mi:SH3GL1(display_short)|uniprotkb:hCG_21932(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|refseq:NP_003016.1|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR028501|interpro:IPR036028|interpro:IPR035824	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Qzz+R0MGXEpZ6G0xoPglUBKBIfk9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	intact:EBI-20723938	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	-	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:h7by58_human(display_short)|psi-mi:EBI-20723938(display_long)|uniprotkb:PCMT1(gene name)|psi-mi:PCMT1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	uniprotkb:H7BY58(uniprot-removed-ac)	-	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:+cZySiAx2KtulFh5qKwajYbly189606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:O60884	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-352957|ensembl:ENSP00000314030|uniprotkb:O14711|uniprotkb:B2R7L7	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:dnja2_human(display_long)|uniprotkb:DNAJA2(gene name)|psi-mi:DNAJA2(display_short)|uniprotkb:HIRIP4(gene name synonym)|uniprotkb:CPR3(gene name synonym)|uniprotkb:HIRA-interacting protein 4(gene name synonym)|uniprotkb:Cell cycle progression restoration gene 3 protein(gene name synonym)|uniprotkb:Dnj3(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-14(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000069345(gene)|ensembl:ENST00000317089(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:O60884|reactome:R-HSA-3371497|interpro:IPR018253|refseq:NP_005871.1|dip:DIP-33143N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:c+JdHn0cKVKqRZCvK6DRYWs+zkQ9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A140VJL3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26518993	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a140vjl3_human(display_long)|uniprotkb:HPRT1(gene name)|psi-mi:HPRT1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0000166"(nucleotide binding)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0021756"(striatum development)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0032263"(GMP salvage)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046083"(adenine metabolic process)|go:"GO:0046100"(hypoxanthine metabolic process)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0052657"(guanine phosphoribosyltransferase activity)|go:"GO:0032264"(IMP salvage)|refseq:NP_000185.1|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:w87Sv/qOAkHFqJm0vu0Ayqlz7TA9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P09382	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1048875|uniprotkb:B2R5E8|uniprotkb:Q9UDK5|ensembl:ENSP00000215909	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:leg1_human(display_long)|uniprotkb:Lectin galactoside-binding soluble 1(gene name synonym)|uniprotkb:Beta-galactoside-binding lectin L-14-I(gene name synonym)|uniprotkb:S-Lac lectin 1(gene name synonym)|uniprotkb:Galaptin(gene name synonym)|uniprotkb:14 kDa lectin(gene name synonym)|uniprotkb:HPL(gene name synonym)|uniprotkb:HBL(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM12(gene name synonym)|uniprotkb:LGALS1(gene name)|psi-mi:LGALS1(display_short)|uniprotkb:Lactose-binding lectin 1(gene name synonym)|uniprotkb:14 kDa laminin-binding protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_002296.1|ensembl:ENST00000215909(transcript)|go:"GO:0002317"(plasma cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030395"(lactose binding)|ensembl:ENSG00000100097(gene)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P09382|rcsb pdb:1GZW|rcsb pdb:1W6M|rcsb pdb:1W6N|rcsb pdb:1W6O|rcsb pdb:1W6P|rcsb pdb:1W6Q|rcsb pdb:2KM2|rcsb pdb:2ZKN|rcsb pdb:3OY8|rcsb pdb:3OYW|rcsb pdb:3T2T|rcsb pdb:3W58|rcsb pdb:3W59|rcsb pdb:4Q1P|go:"GO:0031295"(T cell costimulation)|go:"GO:0034120"(positive regulation of erythrocyte aggregation)|go:"GO:0035900"(response to isolation stress)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043236"(laminin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0048678"(response to axon injury)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4Q1R|rcsb pdb:4Q26|rcsb pdb:4Q27|rcsb pdb:4Q2F|rcsb pdb:4XBL|rcsb pdb:4Y1U|rcsb pdb:4Y1V|rcsb pdb:4Y1X|rcsb pdb:4Y1Y|rcsb pdb:4Y1Z|rcsb pdb:4Y20|rcsb pdb:4Y22|rcsb pdb:4Y24|rcsb pdb:5MWT|rcsb pdb:5MWX|rcsb pdb:6B94|rcsb pdb:6F83|rcsb pdb:6M5Y|reactome:R-HSA-381426|reactome:R-HSA-8957275|dip:DIP-46153N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Sov3RfY2NOjdjuvdFlEd/vaNTMY9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A0F7KYT8	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21360750	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a0f7kyt8_human(display_long)|uniprotkb:FXR1(gene name)|psi-mi:FXR1(display_short)|uniprotkb:hCG_2021334(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007517"(muscle organ development)|refseq:XP_005247870.2|interpro:IPR008395(Agenet)|interpro:IPR040148|interpro:IPR040472|interpro:IPR022034|interpro:IPR032172|interpro:IPR032177|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|interpro:IPR041560	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:08WVozuntzLkCNzbWlOVhiwUpKM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024RDL1	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26518976	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024rdl1_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:hCG_18831(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|refseq:NP_001753.1|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|interpro:IPR027410	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P17812	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1042983|uniprotkb:Q5VW67|uniprotkb:Q96GK6|ensembl:ENSP00000361699|ensembl:ENSP00000497602|ensembl:ENSP00000497744|uniprotkb:D3DPW1|uniprotkb:B4DR64	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:pyrg1_human(display_long)|uniprotkb:CTPS1(gene name)|psi-mi:CTPS1(display_short)|uniprotkb:CTP synthetase 1(gene name synonym)|uniprotkb:CTPS(gene name synonym)|uniprotkb:UTP--ammonia ligase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000171793(gene)|ensembl:ENST00000372616(transcript)|ensembl:ENST00000649124(transcript)|ensembl:ENST00000650070(transcript)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0097268"(cytoophidium)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|interpro:IPR033828|mint:P17812|rcsb pdb:2VO1|rcsb pdb:5U03|reactome:R-HSA-499943|refseq:NP_001288166.1|refseq:NP_001896.2	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:0QkxA3YRejXU0X7dk7zf1XeAMt89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q6XZF7	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-2483419|ensembl:ENSP00000315659|uniprotkb:Q8IVY3|uniprotkb:Q9Y2L3	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:dnmbp_human(display_long)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007568"(aging)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045202"(synapse)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0098793"(presynapse)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035469|interpro:IPR035817|interpro:IPR035818|interpro:IPR035819|interpro:IPR035820|interpro:IPR035899|interpro:IPR036028|mint:Q6XZF7|rcsb pdb:1UG1|rcsb pdb:1UHC|rcsb pdb:4CC2|rcsb pdb:4CC3|rcsb pdb:4CC4|rcsb pdb:4CC7|rcsb pdb:4GLM|reactome:R-HSA-9013148|refseq:XP_011537861.1|refseq:NP_056036.1|refseq:NP_001305255.1|refseq:NP_001305256.1|dip:DIP-53822N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P31689	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-347834|ensembl:ENSP00000369127|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000086061(gene)|ensembl:ENST00000330899(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|reactome:R-HSA-3371497|rcsb pdb:6E8M|refseq:NP_001530.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q59H77	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-10825733	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q59h77_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_005989.3|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|interpro:IPR027410|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:tn8HSeQgYEs249MFFURgFAPpceg9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P27348	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A087WZT3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-12006120|ensembl:ENSP00000306752|ensembl:ENSP00000482868	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a087wzt3_human(display_long)|uniprotkb:BOLA2B(gene name)|psi-mi:BOLA2B(display_short)|uniprotkb:BOLA2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000169627(gene)|ensembl:ENSG00000183336(gene)|ensembl:ENST00000305321(transcript)|ensembl:ENST00000380596(transcript)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|refseq:NP_001026997.1|refseq:NP_001034271.1|refseq:XP_016855107.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:rW/b1xR3prAOe+MsPM8GgNgqqg49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A8K0T9	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-9977422	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a8k0t9_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|go:"GO:0003779"(actin binding)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0051016"(barbed-end actin filament capping)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:yxFcTATzQ0qEKNTN+2IaOYWGGIo9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B2R6S4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26518960	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b2r6s4_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR035882|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR000980(SH2 motif)|interpro:IPR036860|interpro:IPR036028|interpro:IPR001452(Src homology-3)|interpro:IPR028526	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:BRQv7lOrmMvn9foku446gFhdJ409606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q8IXB1	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-2949763|ensembl:ENSP00000264065|uniprotkb:Q53QT7|uniprotkb:Q6UWZ6|uniprotkb:Q96K44|uniprotkb:Q8NC82|uniprotkb:Q86T61|uniprotkb:Q9NSY6|uniprotkb:Q17RJ6|uniprotkb:Q8TD87|uniprotkb:Q96K54|uniprotkb:Q96K38|uniprotkb:Q4ZG06|uniprotkb:Q3B7W8	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:djc10_human(display_long)|uniprotkb:DNAJC10(gene name)|psi-mi:DNAJC10(display_short)|uniprotkb:ERDJ5(gene name synonym)|uniprotkb:Macrothioredoxin(gene name synonym)|uniprotkb:UNQ495/PRO1012(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000077232(gene)|ensembl:ENST00000264065(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0016020"(membrane)|go:"GO:0016671"(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR021170|interpro:IPR035673|interpro:IPR035674|interpro:IPR036249|interpro:IPR036869|mint:Q8IXB1|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|refseq:NP_061854.1|refseq:NP_001258510.1|dip:DIP-48947N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:sD/pp49jws0LrBjwCxQmZqzfR9U9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A0A0MTN0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21353456|ensembl:ENSP00000444856	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a0a0mtn0_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|interpro:IPR016158(Cullin homology)|ensembl:ENSG00000108094(gene)|ensembl:ENST00000537177(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|refseq:NP_001185708.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:VyN1erHQGN0XlzwDMlLFKhmfANw9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q59EI9	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21358374	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q59ei9_human(display_long)|uniprotkb:ADP,ATP carrier protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:9XFgWtOMJkRg9H1jyCZYFcBKgIY9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B7Z2P6	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26518949	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b7z2p6_human(display_long)|uniprotkb:Peroxisomal biogenesis factor 19(gene name synonym)|uniprotkb:Peroxisomal farnesylated protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005778"(peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|interpro:IPR006708(Pex19 protein)|interpro:IPR038322|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR036322	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:StcaoU5tz6hVEFilQy/8DR7dG2o9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q6NVC0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21357336	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q6nvc0_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ADP,ATP carrier protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|refseq:NP_001143.2|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:QDMYWcD6hKwQOapIY9uIJRaYUrQ9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9HBB3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-11602801	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q9hbb3_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR041997|go:"GO:0003677"(DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:EVY0+ED/IWQAVWkdyeQmycTXWTM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P0CG39	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-6151401|ensembl:ENSP00000387176	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:potej_human(display_long)|uniprotkb:POTEJ(gene name)|psi-mi:POTEJ(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001264012.1|ensembl:ENSG00000222038(gene)|ensembl:ENST00000409602(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005615"(extracellular space)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002110(Ankyrin)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020683|interpro:IPR020902|interpro:IPR036770|interpro:IPR039497|interpro:IPR043129	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:FjaGG32SBA1jpjo0RFJpJ0gAyM89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:D3DNI2	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21358824	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:d3dni2_human(display_long)|uniprotkb:PFN2(gene name)|psi-mi:PFN2(display_short)|uniprotkb:hCG_21343(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030833"(regulation of actin filament polymerization)|interpro:IPR005455(Profilin, plant)|interpro:IPR029891|interpro:IPR036140|interpro:IPR005454(Profilin, Mammalian)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:UcnXSxXBHztWtmWu1SC49wc0p4M9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P35080	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-473138|uniprotkb:Q8WVF9|uniprotkb:Q9HBK2|uniprotkb:B2R4C8|uniprotkb:Q4VBQ4|uniprotkb:D3DNI4|ensembl:ENSP00000239940	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:prof2_human(display_long)|uniprotkb:PFN2(gene name)|psi-mi:PFN2(display_short)|uniprotkb:Profilin II(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_002619.1|refseq:NP_444252.1|ensembl:ENSG00000070087(gene)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010633"(negative regulation of epithelial cell migration)|ensembl:ENST00000239940(transcript)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900028"(negative regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029891|interpro:IPR036140|mint:P35080|rcsb pdb:1D1J|reactome:R-HSA-376176|reactome:R-HSA-5663220	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:064T9afVEb7WrgJPLVbKByJDUXc9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q15084	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1043087|uniprotkb:Q6ZSH5|ensembl:ENSP00000272227|uniprotkb:B3KY95|uniprotkb:B5MCQ5|uniprotkb:B7Z4M8|uniprotkb:F8WA83|uniprotkb:B7Z254|uniprotkb:Q99778|uniprotkb:Q53RC7	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:pdia6_human(display_long)|uniprotkb:PDIA6(gene name)|psi-mi:PDIA6(display_short)|uniprotkb:TXNDC7(gene name synonym)|uniprotkb:Protein disulfide isomerase P5(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 7(gene name synonym)|uniprotkb:ERP5(gene name synonym)|uniprotkb:P5(gene name synonym)|uniprotkb:Endoplasmic reticulum protein 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001269633.1|refseq:NP_001269634.1|refseq:NP_001269635.1|refseq:NP_001269636.1|interpro:IPR036249|interpro:IPR044569|mint:Q15084|rcsb pdb:1X5D|rcsb pdb:3VWW|rcsb pdb:3W8J|rcsb pdb:4EF0|rcsb pdb:4GWR|reactome:R-HSA-381038|reactome:R-HSA-381426|reactome:R-HSA-8957275|interpro:IPR017937|ensembl:ENSG00000143870(gene)|ensembl:ENST00000272227(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005733.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:411bo7TdfeCtMvUqyBb7bofi5To9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q1HBJ4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21352189	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q1hbj4_human(display_long)|uniprotkb:MAPK1(gene name)|psi-mi:MAPK1(display_short)|uniprotkb:hCG_32557(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035094"(response to nicotine)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043627"(response to estrogen)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046697"(decidualization)|go:"GO:0031143"(pseudopodium)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019858"(cytosine metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0007568"(aging)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0048538"(thymus development)|refseq:NP_002736.3|refseq:NP_620407.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:odzhd70I/8uWedx0+gF38lhe60I9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q6PUJ7	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21358735	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q6puj7_human(display_long)|uniprotkb:HEL-215(gene name)|psi-mi:HEL-215(display_short)|uniprotkb:HEL-S-54e(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|interpro:IPR000163(Prohibitin)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:wS2eD78si/8ouylPTm7hVuiJ4x89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q14204	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-356015|intact:EBI-4399546|uniprotkb:Q6DKQ7|uniprotkb:Q8WU28|uniprotkb:Q92814|uniprotkb:Q9Y4G5|uniprotkb:B0I1R0|intact:EBI-28969816|ensembl:ENSP00000348965	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:dyhc1_human(display_long)|uniprotkb:DYNC1H1(gene name)|psi-mi:DYNC1H1(display_short)|uniprotkb:DNECL(gene name synonym)|uniprotkb:KIAA0325(gene name synonym)|uniprotkb:DNCH1(gene name synonym)|uniprotkb:DNCL(gene name synonym)|uniprotkb:DHC1(gene name synonym)|uniprotkb:DYHC(gene name synonym)|uniprotkb:Cytoplasmic dynein heavy chain 1(gene name synonym)|uniprotkb:Dynein heavy chain, cytosolic(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001367.2|ensembl:ENSP00000348965|ensembl:ENSG00000197102(gene)|ensembl:ENST00000360184(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0016020"(membrane)|go:"GO:0030175"(filopodium)|go:"GO:0030286"(dynein complex)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051301"(cell division)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072382"(minus-end-directed vesicle transport along microtubule)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024317|interpro:IPR024743|interpro:IPR027417|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041658|interpro:IPR042219|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|mint:Q14204|rcsb pdb:2BOR|rcsb pdb:2BOT|rcsb pdb:5NUG|rcsb pdb:5OWO|rcsb pdb:6F1T|rcsb pdb:6F1U|rcsb pdb:6F1V|rcsb pdb:6F1Y|rcsb pdb:6F38|rcsb pdb:6F3A|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|dip:DIP-37544N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:nI5RCxHByU3dxtLnPMPEjJlx1Fc9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A8K3C3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26518935	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a8k3c3_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR017998|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|interpro:IPR027410	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:98ql/fvNrWNR5YV0B+sEHy6pweA9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q99623	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-358348|uniprotkb:Q2YDA4|uniprotkb:Q7KYU3|uniprotkb:Q92978|ensembl:ENSP00000441875|uniprotkb:B4DP75	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:phb2_human(display_long)|uniprotkb:BAP(gene name synonym)|uniprotkb:REA(gene name synonym)|uniprotkb:PHB2(gene name)|psi-mi:PHB2(display_short)|uniprotkb:D-prohibitin(gene name synonym)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Repressor of estrogen receptor activity(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001138303.1|ensembl:ENSG00000215021(gene)|ensembl:ENST00000535923(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016477"(cell migration)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030424"(axon)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033218"(amide binding)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071944"(cell periphery)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|go:"GO:1990051"(activation of protein kinase C activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:Q99623|rcsb pdb:6IQE|reactome:R-HSA-8949664|refseq:NP_001254629.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:h4pib54mBeQgOKCe/hib58LM26w9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:G8JLB6	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21357942|ensembl:ENSP00000327539	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:g8jlb6_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000169045(gene)|ensembl:ENST00000329433(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|refseq:XP_005265952.1|refseq:XP_005265953.1|refseq:XP_011532844.1|refseq:XP_011532846.1|refseq:XP_011532847.1|refseq:XP_011532848.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:SUyfrDnUyHSIh8tkTKJQSqp73Es9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A8K7B7	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-10174513	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a8k7b7_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:hCG_19686(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|refseq:NP_055040.2|interpro:IPR031090|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0065003"(protein-containing complex assembly)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P32119	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1266300|uniprotkb:P31945|uniprotkb:P32118|uniprotkb:P35701|uniprotkb:Q6FHG4|uniprotkb:Q92763|uniprotkb:Q9UC23|uniprotkb:A8K0C0|ensembl:ENSP00000301522	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:prdx2_human(display_long)|uniprotkb:PRDX2(gene name)|psi-mi:PRDX2(display_short)|uniprotkb:NKEFB(gene name synonym)|uniprotkb:TDPX1(gene name synonym)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor B(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_005800.3|dip:DIP-39882N|ensembl:ENSG00000167815(gene)|ensembl:ENST00000301522(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:P32119|rcsb pdb:1QMV|rcsb pdb:5B8A|rcsb pdb:5B8B|rcsb pdb:5IJT|rcsb pdb:7KIZ|rcsb pdb:7KJ0|rcsb pdb:7KJ1|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:F8+7/3HrAcJq7BjkZaig16mCOO89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:V9HWC2	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26518884	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:v9hwc2_human(display_long)|uniprotkb:HEL-S-67p(gene name)|psi-mi:HEL-S-67p(display_short)|uniprotkb:Parkinsonism-associated deglycase(gene name synonym)|uniprotkb:Protein DJ-1(gene name synonym)|uniprotkb:Protein/nucleic acid deglycase DJ-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:2000277"(positive regulation of oxidative phosphorylation uncoupler activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007338"(single fertilization)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0002866"(positive regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0030073"(insulin secretion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0036471"(cellular response to glyoxal)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046295"(glycolate biosynthetic process)|go:"GO:0050787"(detoxification of mercury ion)|go:"GO:0050821"(protein stabilization)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070994"(detection of oxidative stress)|go:"GO:0098793"(presynapse)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902958"(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:"GO:1903189"(glyoxal metabolic process)|go:"GO:1903384"(negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|refseq:NP_001116849.1|refseq:NP_009193.2|refseq:XP_005263481.1|interpro:IPR029062|interpro:IPR006287(DJ-1)|interpro:IPR002818(ThiJ/PfpI)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:i5ah4UPCf+4cD51ClZNggMFJMDo9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q96RF0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-298169|uniprotkb:Q05BB3|uniprotkb:Q0VG02|ensembl:ENSP00000342276|uniprotkb:B4E2B3|uniprotkb:H7BXX3	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:snx18_human(display_long)|uniprotkb:SNX18(gene name)|psi-mi:SNX18(display_short)|uniprotkb:SH3 and PX domain-containing protein 3B(gene name synonym)|uniprotkb:SH3PXD3B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001096045.1|refseq:NP_001138899.1|refseq:NP_443102.2|ensembl:ENSG00000178996(gene)|go:"GO:0006897"(endocytosis)|ensembl:ENST00000343017(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|interpro:IPR027267|interpro:IPR028646|interpro:IPR035557|interpro:IPR035703|interpro:IPR036028|interpro:IPR036871|mint:Q96RF0|reactome:R-HSA-8856828	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:HpHLfTZ0EfhC6oMHeSr1GCgZaI49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q8WV41	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-2481535|ensembl:ENSP00000311427|uniprotkb:B1NM17	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:snx33_human(display_long)|uniprotkb:SNX33(gene name)|psi-mi:SNX33(display_short)|uniprotkb:SH3PX3(gene name synonym)|uniprotkb:SH3PXD3C(gene name synonym)|uniprotkb:SNX30(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000173548(gene)|ensembl:ENST00000308527(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0016020"(membrane)|go:"GO:0017038"(protein import)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044351"(macropinocytosis)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|interpro:IPR027267|interpro:IPR028642|interpro:IPR036028|interpro:IPR036871|interpro:IPR037427|mint:Q8WV41|rcsb pdb:4AKV|go:"GO:0016197"(endosomal transport)|refseq:NP_695003.1|refseq:NP_001305075.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:rhvspe+J40o9M1MJtpUIyeQFLRs9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:V9HWB8	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-10215395	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:v9hwb8_human(display_long)|uniprotkb:HEL-S-30(gene name)|psi-mi:HEL-S-30(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|refseq:NP_002645.3|refseq:XP_005254502.1|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0016301"(kinase activity)|go:"GO:0030955"(potassium ion binding)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR040442|interpro:IPR036918	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:dDaoXCaqd0x6qFSElvngHusttuk9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q93008	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-302524|intact:EBI-1058656|intact:EBI-28978998|ensembl:ENSP00000367558|uniprotkb:O75550|uniprotkb:Q8WWT3|uniprotkb:Q8WX12	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:usp9x_human(display_long)|uniprotkb:USP9X(gene name)|psi-mi:USP9X(display_short)|uniprotkb:DFFRX(gene name synonym)|uniprotkb:USP9(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease FAF-X(gene name synonym)|uniprotkb:Deubiquitinating enzyme FAF-X(gene name synonym)|uniprotkb:Fat facets protein-related, X-linked(gene name synonym)|uniprotkb:Ubiquitin-specific protease 9, X chromosome(gene name synonym)|uniprotkb:FAM(gene name synonym)|uniprotkb:Fat facets in mammals(gene name synonym)|uniprotkb:Ubiquitin thioesterase FAF-X(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000124486(gene)|ensembl:ENST00000378308(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007292"(female gamete generation)|go:"GO:0008104"(protein localization)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030426"(growth cone)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|reactome:R-HSA-2173795|reactome:R-HSA-5689880|reactome:R-HSA-8866652|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9033241|reactome:R-HSA-977225|go:"GO:0048675"(axon extension)|refseq:NP_001034679.2|refseq:NP_001034680.2|go:"GO:0050821"(protein stabilization)|go:"GO:0051301"(cell division)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018200|interpro:IPR021905|interpro:IPR028889|interpro:IPR031226|interpro:IPR038765|mint:Q93008|rcsb pdb:5VBD|rcsb pdb:5WCH|ensembl:ENST00000324545|ensembl:ENSP00000316357|ensembl:ENSP00000367558|dip:DIP-27562N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:f9AWz8rAV8rMTqcQ46VrYYLTHq89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B5BUB1	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-9512878	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b5bub1_human(display_long)|uniprotkb:RUVBL1(gene name)|psi-mi:RUVBL1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR037938|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|interpro:IPR027238|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR041048|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:aBcJKlV75E/3Ht94Dp+scTxvelc9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P11802	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-295644|uniprotkb:O00576|uniprotkb:Q6FG61|uniprotkb:B4DNF9|uniprotkb:B2R9A0|ensembl:ENSP00000257904	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:cdk4_human(display_long)|uniprotkb:CDK4(gene name)|psi-mi:CDK4(display_short)|uniprotkb:Cell division protein kinase 4(gene name synonym)|uniprotkb:PSK-J3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_000066.1|dip:DIP-875N|ensembl:ENSG00000135446(gene)|ensembl:ENST00000257904(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000785"(chromatin)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030332"(cyclin binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033574"(response to testosterone)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046890"(regulation of lipid biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050994"(regulation of lipid catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097129"(cyclin D2-CDK4 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1904637"(cellular response to ionomycin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P11802|rcsb pdb:1LD2|rcsb pdb:2W96|rcsb pdb:2W99|rcsb pdb:2W9F|rcsb pdb:2W9Z|rcsb pdb:3G33|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:6P8G|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-2559580|rcsb pdb:6P8E|rcsb pdb:6P8F|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-69231|reactome:R-HSA-75815|reactome:R-HSA-8849470|reactome:R-HSA-8878166|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9630791|reactome:R-HSA-9630794|reactome:R-HSA-9632697|reactome:R-HSA-9632700|reactome:R-HSA-9661069	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:pxIzF9EkX+gMz7zj/TDiytYtsOc9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P52597	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-352986|ensembl:ENSP00000338477|ensembl:ENSP00000349573|ensembl:ENSP00000400433|ensembl:ENSP00000438061|ensembl:ENSP00000507787|ensembl:ENSP00000348345|uniprotkb:Q5T0N2|uniprotkb:Q96AU2|uniprotkb:B3KM84	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:hnrpf_human(display_long)|uniprotkb:HNRNPF(gene name)|psi-mi:HNRNPF(display_short)|uniprotkb:HNRPF(gene name synonym)|uniprotkb:Nucleolin-like protein mcs94-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P52597|rcsb pdb:2HGL|rcsb pdb:2HGM|rcsb pdb:2HGN|rcsb pdb:2KFY|rcsb pdb:2KG0|rcsb pdb:2KG1|rcsb pdb:3TFY|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000169813(gene)|ensembl:ENST00000337970(transcript)|ensembl:ENST00000356053(transcript)|ensembl:ENST00000357065(transcript)|ensembl:ENST00000443950(transcript)|ensembl:ENST00000544000(transcript)|ensembl:ENST00000682386(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001091674.1|refseq:NP_001091675.1|refseq:NP_001091676.1|refseq:NP_001091677.1|refseq:NP_001091678.1|refseq:NP_004957.1|dip:DIP-33145N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:pblzpldZOa5vlZ+zGQY9qyWCxaw9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P13639	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-352560|uniprotkb:Q58J86|uniprotkb:B2RMP5|uniprotkb:D6W618|ensembl:ENSP00000307940	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:ef2_human(display_long)|uniprotkb:EEF2(gene name)|psi-mi:EEF2(display_short)|uniprotkb:EF2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001952.1|ensembl:ENSG00000167658(gene)|ensembl:ENST00000309311(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P13639|rcsb pdb:4V6X|rcsb pdb:6D9J|rcsb pdb:6Z6M|rcsb pdb:6Z6N|reactome:R-HSA-156902|reactome:R-HSA-5336415|reactome:R-HSA-5358493|reactome:R-HSA-6798695|reactome:R-HSA-8876725	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:US1dzGQ5V1oBXVtYeGt5H3HCIr09606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P50990	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A8K5Y2	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26518873	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a8k5y2_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005737"(cytoplasm)|interpro:IPR027267|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR035470|interpro:IPR004148(BAR)|interpro:IPR036028|interpro:IPR001452(Src homology-3)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:7kB/ZPe1+TAT0ke2Opmz9vUJ1kg9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:V9HW31	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-10266742	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:v9hw31_human(display_long)|uniprotkb:HEL-S-271(gene name)|psi-mi:HEL-S-271(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|refseq:NP_001677.2|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR036121	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:oLPUvG1tQkkzxzeAG6R0ZkZF+eg9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B7Z2B0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21360173	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b7z2b0_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR032710|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Tg4rPWCfSIQETLr8bMKlQJ2yrFg9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P07195	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-358748|ensembl:ENSP00000229319|ensembl:ENSP00000379386	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:ldhb_human(display_long)|uniprotkb:LDHB(gene name)|psi-mi:LDHB(display_short)|uniprotkb:LDH heart subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-46(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001167568.1|refseq:NP_002291.1|refseq:NP_001302466.1|ensembl:ENSG00000111716(gene)|ensembl:ENST00000350669(transcript)|ensembl:ENST00000396076(transcript)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P07195|rcsb pdb:1I0Z|rcsb pdb:1T2F|reactome:R-HSA-70268	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:umdj6fjSO7+4SM9Hrl1/K2EiKls9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q6ZS11	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26518845|intact:EBI-28970567|ensembl:ENSP00000467107|ensembl:ENSP00000489071|uniprotkb:B4DPG5	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rinl_human(display_long)|uniprotkb:RINL(gene name)|psi-mi:RINL(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSP00000467107|ensembl:ENST00000598904|ensembl:ENSP00000469568|ensembl:ENST00000635328|ensembl:ENSP00000488992|ensembl:ENSP00000489071|ensembl:ENSG00000187994(gene)|ensembl:ENST00000591812(transcript)|ensembl:ENST00000635542(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0031410"(cytoplasmic vesicle)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR036860|interpro:IPR037191|reactome:R-HSA-8876198|ensembl:ENSG00000282895(gene)|refseq:NP_001182762.1|refseq:NP_940847.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Y8q/MX1LNHNCZ9XWOV7S3NWOUHg9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B2RDW1	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-2339597|uniprotkb:D6W5C9	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b2rdw1_human(display_long)|uniprotkb:HEL112(gene name)|psi-mi:HEL112(display_short)|uniprotkb:RPS27A(gene name synonym)|uniprotkb:Ubiquitin carboxyl extension protein 80(gene name synonym)|uniprotkb:Ubiquitin-40S ribosomal protein S27a(gene name synonym)|uniprotkb:hCG_1987923(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001129064.1|refseq:NP_001170884.1|refseq:NP_002945.1|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR038582|interpro:IPR029071|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0046872"(metal ion binding)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:2LSJafy6vjKHYZcZVx8zZaOXRis9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024RD80	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26518782	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024rd80_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:hCG_19001(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031526"(brush border membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032564"(dATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042220"(response to cocaine)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:0044295"(axonal growth cone)|go:"GO:1990917"(ooplasm)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0005524"(ATP binding)|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_031381.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR036890|interpro:IPR019805|interpro:IPR037196|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:wOsW7C10v2oMsM+REE38K6PAan09606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P21333	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024R3X4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26518726|uniprotkb:A0A024R3W0	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024r3x4_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:60 kDa heat shock protein, mitochondrial(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:hCG_2012240(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002931"(response to ischemia)|go:"GO:0005524"(ATP binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033198"(response to ATP)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042110"(T cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|refseq:NP_002147.2|refseq:NP_955472.1|interpro:IPR018370|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|interpro:IPR027410	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:syB2vt66Cpr2mJROfbxoPevoiRE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A8K3K1	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26518713	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a8k3k1_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005737"(cytoplasm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0044297"(cell body)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR004001(Actin, conserved site)|interpro:IPR043129	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:0WZ402PsLo2F3y7LndLIU3bE/t89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9Y230	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-352939|ensembl:ENSP00000473172|uniprotkb:Q6FIB9|uniprotkb:Q6PK27|uniprotkb:Q9Y361|uniprotkb:B3KQ59|uniprotkb:E7ETE5|intact:EBI-1058527	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:ruvb2_human(display_long)|uniprotkb:RUVBL2(gene name)|psi-mi:RUVBL2(display_short)|uniprotkb:TIP48(gene name synonym)|uniprotkb:TIP49B(gene name synonym)|uniprotkb:CGI-46(orf name)|uniprotkb:48 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49b(gene name synonym)|uniprotkb:Repressing pontin 52(gene name synonym)|uniprotkb:51 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80J(gene name synonym)|uniprotkb:TIP60-associated protein 54-beta(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|mint:Q9Y230|rcsb pdb:2CQA|rcsb pdb:2XSZ|rcsb pdb:3UK6|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6H7X|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|go:"GO:0140585"(promoter-enhancer loop anchoring activity)|reactome:R-HSA-3214847|ensembl:ENSG00000183207(gene)|ensembl:ENST00000595090(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000791"(euchromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006457"(protein folding)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0016573"(histone acetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|refseq:NP_006657.1|refseq:XP_011524632.1|refseq:NP_001308120.1|dip:DIP-28153N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:APKAWLDCJVULUP3nzqIaSLHKVN49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q06830	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-353193|ensembl:ENSP00000262746|ensembl:ENSP00000361152|ensembl:ENSP00000389047|ensembl:ENSP00000407034|ensembl:ENSP00000503140|uniprotkb:P35703|uniprotkb:Q2V576|uniprotkb:Q5T154|uniprotkb:Q5T155|uniprotkb:B5BU26|uniprotkb:D3DPZ8	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:prdx1_human(display_long)|uniprotkb:PRDX1(gene name)|psi-mi:PRDX1(display_short)|uniprotkb:PAGA(gene name synonym)|uniprotkb:PAGB(gene name synonym)|uniprotkb:TDPX2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Proliferation-associated gene protein(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor A(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000117450(gene)|ensembl:ENST00000262746(transcript)|ensembl:ENST00000319248(transcript)|ensembl:ENST00000424390(transcript)|ensembl:ENST00000447184(transcript)|ensembl:ENST00000676549(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003723"(RNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042470"(melanosome)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q06830|rcsb pdb:2RII|rcsb pdb:3HY2|rcsb pdb:4XCS|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803|refseq:NP_001189360.1|refseq:NP_002565.1|refseq:NP_859047.1|refseq:NP_859048.1|dip:DIP-33152N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:ZM5ZXF900izH81QVqgd2+opwMrs9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A0S2Z3Q4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26518665	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a0s2z3q4_human(display_long)|uniprotkb:CRK(gene name)|psi-mi:CRK(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0001764"(neuron migration)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061847"(response to cholecystokinin)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990859"(cellular response to endothelin)|go:"GO:2000404"(regulation of T cell migration)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035728"(response to hepatocyte growth factor)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045121"(membrane raft)|go:"GO:0001878"(response to yeast)|refseq:NP_058431.2|interpro:IPR035458|interpro:IPR035457|interpro:IPR000980(SH2 motif)|interpro:IPR036860|interpro:IPR036028|interpro:IPR001452(Src homology-3)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:lIXCzFxFvmvsfPaLQIKV9QS75cw9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q96B97	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-346595|uniprotkb:Q8IWX6|uniprotkb:Q8IX98|uniprotkb:Q96RN4|uniprotkb:Q9NYR0|uniprotkb:B7Z1D5|uniprotkb:Q5JPT4|uniprotkb:Q5JPT5|ensembl:ENSP00000380921	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:sh3k1_human(display_long)|uniprotkb:SH3KBP1(gene name)|psi-mi:SH3KBP1(display_short)|uniprotkb:CIN85(gene name synonym)|uniprotkb:Cbl-interacting protein of 85 kDa(gene name synonym)|uniprotkb:Human Src family kinase-binding protein 1(gene name synonym)|uniprotkb:CD2-binding protein 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001019837.1|refseq:NP_114098.1|refseq:NP_001171889.1|refseq:XP_016884958.1|dip:DIP-31803N|ensembl:ENSG00000147010(gene)|ensembl:ENST00000397821(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0050871"(positive regulation of B cell activation)|interpro:IPR001452(Src homology-3)|interpro:IPR028506|interpro:IPR035770|interpro:IPR035771|interpro:IPR035772|interpro:IPR036028|mint:Q96B97|rcsb pdb:2BZ8|rcsb pdb:2K6D|rcsb pdb:2K9G|rcsb pdb:2N64|rcsb pdb:2O2O|rcsb pdb:2YDL|rcsb pdb:5ABS|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866376|reactome:R-HSA-8875360|reactome:R-HSA-983695|go:"GO:0007015"(actin filament organization)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:WB37Fbtwe/IA57zPOHhbmdNNI1s9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A087WVQ6	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21358342|ensembl:ENSP00000479606	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a087wvq6_human(display_long)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:hCG_1818599(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000141367(gene)|ensembl:ENST00000621829(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0071439"(clathrin complex)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_001275582.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:hwcIaETMP3biOXfZBoVoT1jqJIQ9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P63208	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9UK99	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-2509901|uniprotkb:B3KY16|uniprotkb:D3DR05|uniprotkb:Q9H0V2|uniprotkb:Q86X90|uniprotkb:Q9NUX2|ensembl:ENSP00000265651	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:fbx3_human(display_long)|uniprotkb:FBXO3(gene name)|psi-mi:FBXO3(display_short)|uniprotkb:FBX3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_036307.2|refseq:NP_208385.1|dip:DIP-53688N|ensembl:ENSG00000110429(gene)|ensembl:ENST00000265651(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007474(ApaG)|interpro:IPR018958|interpro:IPR028388|interpro:IPR036047|interpro:IPR036767|interpro:IPR037883|rcsb pdb:5HDW	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:zQB8ig3s51tXN81NtMrou84Rv6I9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:K9JA46	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-9392866	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:k9ja46_human(display_long)|uniprotkb:EL52(gene name)|psi-mi:EL52(display_short)|uniprotkb:HSP90AA1(gene name synonym)|uniprotkb:hCG_1814169(orf name)|uniprotkb:HEL-S-65p(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|refseq:NP_005339.3|interpro:IPR036890|interpro:IPR037196|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0042470"(melanosome)|go:"GO:0046677"(response to antibiotic)|go:"GO:0051082"(unfolded protein binding)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:O60504	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-741237|ensembl:ENSP00000240123|uniprotkb:Q5BJE4|uniprotkb:Q6NX54|uniprotkb:Q9UQE4|intact:EBI-1222937|uniprotkb:Q96FY4	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:vinex_human(display_long)|uniprotkb:SCAM1(gene name synonym)|uniprotkb:SH3-containing adapter molecule 1(gene name synonym)|uniprotkb:Sorbin and SH3 domain-containing protein 3(gene name synonym)|uniprotkb:SORBS3(gene name)|psi-mi:SORBS3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000120896(gene)|ensembl:ENST00000240123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0017166"(vinculin binding)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR028510|interpro:IPR035607|interpro:IPR035608|interpro:IPR035609|interpro:IPR036028|mint:O60504|rcsb pdb:2CT3|rcsb pdb:2DLM|rcsb pdb:2NWM|rcsb pdb:2YUP|reactome:R-HSA-445355|refseq:NP_001018003.1|refseq:NP_005766.3|refseq:XP_005273428.1|refseq:XP_016868433.1|refseq:XP_016868434.1|refseq:XP_016868435.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Mq3VXduU/1gqfUwliO9sBBOb/Vc9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P49327	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-356658|uniprotkb:Q4LE83|uniprotkb:Q13479|uniprotkb:Q16702|uniprotkb:Q6P4U5|uniprotkb:Q6SS02|uniprotkb:Q969R1|uniprotkb:Q96C68|uniprotkb:Q96IT0|ensembl:ENSP00000304592	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:fas_human(display_long)|uniprotkb:FASN(gene name)|psi-mi:FASN(display_short)|uniprotkb:FAS(gene name synonym)|uniprotkb:Type I fatty acid synthase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_004095.4|ensembl:ENSG00000169710(gene)|ensembl:ENST00000306749(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003723"(RNA binding)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0016020"(membrane)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P49327|rcsb pdb:1XKT|rcsb pdb:2CG5|rcsb pdb:2JFD|rcsb pdb:2JFK|rcsb pdb:2PX6|rcsb pdb:3HHD|rcsb pdb:3TJM|rcsb pdb:4PIV|rcsb pdb:4W82|rcsb pdb:4W9N|rcsb pdb:4Z49|rcsb pdb:5C37|rcsb pdb:6NNA|reactome:R-HSA-163765|reactome:R-HSA-199220|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|refseq:XP_011521840.1|dip:DIP-33681N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:bQYEH/uQ6l+SPzLBDNCV5yP+yzs9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q16531	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B1AK88	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-11897454|ensembl:ENSP00000401010	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b1ak88_human(display_long)|uniprotkb:CAPZB(gene name)|psi-mi:CAPZB(display_short)|uniprotkb:hCG_41078(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000077549(gene)|ensembl:ENST00000433834(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0030017"(sarcomere)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|refseq:NP_001269091.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:L1VAyy2Te2+ptydVZdFbk6Io0y09606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9UNF0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-742503|uniprotkb:O95921|uniprotkb:Q96HV9|uniprotkb:Q9H0D3|uniprotkb:Q9NPN1|uniprotkb:Q9Y4V2|ensembl:ENSP00000385040|ensembl:ENSP00000385372|ensembl:ENSP00000263246	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:pacn2_human(display_long)|uniprotkb:PACSIN2(gene name)|psi-mi:PACSIN2(display_short)|uniprotkb:Syndapin-II(gene name synonym)|uniprotkb:Syndapin-2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001171899.1|refseq:NP_001171900.1|refseq:NP_009160.2|refseq:XP_005261376.1|refseq:XP_016884053.1|ensembl:ENST00000263246(transcript)|ensembl:ENST00000402229(transcript)|ensembl:ENST00000403744(transcript)|go:"GO:0005215"(transporter activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000100266(gene)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0032587"(ruffle membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0070836"(caveola assembly)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028521|interpro:IPR031160|interpro:IPR035743|interpro:IPR036028|interpro:IPR037453|mint:Q9UNF0|rcsb pdb:3ABH|rcsb pdb:3ACO|rcsb pdb:3HAJ|rcsb pdb:3Q0K|reactome:R-HSA-8856828	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:oEGsyQlsPg61RRGLjBdPGKDmkXc9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9BUF5	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-356735|uniprotkb:Q9HA42|ensembl:ENSP00000318697|uniprotkb:B3KM76	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:tbb6_human(display_long)|uniprotkb:TUBB6(gene name)|psi-mi:TUBB6(display_short)|uniprotkb:Tubulin beta class V(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000176014(gene)|ensembl:ENST00000317702(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|refseq:NP_115914.1|interpro:IPR036525|interpro:IPR037103|mint:Q9BUF5|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001290453.1|refseq:NP_001290454.1|refseq:NP_001290455.1|refseq:NP_001290456.1|refseq:NP_001290457.1|refseq:NP_001290458.1|refseq:NP_001290459.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:/IC9o8wSAOu+lNgq44Qqu5hEof49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P35908	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1247312|uniprotkb:Q4VAQ2|ensembl:ENSP00000310861	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:k22e_human(display_long)|uniprotkb:KRT2(gene name)|psi-mi:KRT2(display_short)|uniprotkb:KRT2A(gene name synonym)|uniprotkb:KRT2E(gene name synonym)|uniprotkb:Cytokeratin-2e(gene name synonym)|uniprotkb:Keratin-2e(gene name synonym)|uniprotkb:Type-II keratin Kb2(gene name synonym)|uniprotkb:Keratin-2 epidermis(gene name synonym)|uniprotkb:Epithelial keratin-2e(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_000414.2|ensembl:ENSG00000172867(gene)|ensembl:ENST00000309680(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0003334"(keratinocyte development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0031424"(keratinization)|go:"GO:0032980"(keratinocyte activation)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045095"(keratin filament)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P35908|reactome:R-HSA-6805567|reactome:R-HSA-6809371|go:"GO:0051546"(keratinocyte migration)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:T7LeB8nkZzNjUb8DWdkxbrl5f789606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q92625	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1048612|uniprotkb:Q5JYI9|uniprotkb:Q5SYR2|uniprotkb:Q86WQ7|uniprotkb:A2RUC1|ensembl:ENSP00000353518|uniprotkb:B4DQW8	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:ans1a_human(display_long)|uniprotkb:Odin(gene name synonym)|uniprotkb:ANKS1A(gene name)|psi-mi:ANKS1A(display_short)|uniprotkb:ANKS1(gene name synonym)|uniprotkb:KIAA0229(gene name synonym)|uniprotkb:ODIN(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_056060.2|ensembl:ENSG00000064999(gene)|ensembl:ENST00000360359(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006929"(substrate-dependent cell migration)|go:"GO:0016322"(neuron remodeling)|go:"GO:0043005"(neuron projection)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:1901187"(regulation of ephrin receptor signaling pathway)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR033637|interpro:IPR036770|interpro:IPR041880|interpro:IPR041882|mint:Q92625|rcsb pdb:2LMR|rcsb pdb:2MYQ|rcsb pdb:6F7O	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:VTw7RU5nIxHSxvQdBUT/YFlQzU89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024RDS1	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21353685	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024rds1_human(display_long)|uniprotkb:HSPH1(gene name)|psi-mi:HSPH1(display_short)|uniprotkb:Heat shock protein 105 kDa(gene name synonym)|uniprotkb:hCG_32198(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR042053|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|refseq:NP_006635.2|interpro:IPR018181|interpro:IPR029048|interpro:IPR029047|interpro:IPR013126(Heat shock protein 70)|interpro:IPR043129	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:FSdvp2KDHLmNpceRJ9HLY5IBfQA9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P60709	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A140VKE7	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26518654	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a140vke7_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005524"(ATP binding)|refseq:NP_055093.2|interpro:IPR043129|interpro:IPR018181|interpro:IPR029048|interpro:IPR029047|interpro:IPR013126(Heat shock protein 70)|interpro:IPR042708	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:6ZoMlI4t4A4u4YsQgrlcwAqjpi49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P46109	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-910|uniprotkb:A8KA44|intact:EBI-3451075|uniprotkb:D3DX35|ensembl:ENSP00000346300|ensembl:ENSP00000396646	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:crkl_human(display_long)|uniprotkb:CRKL(gene name)|psi-mi:CRKL(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_005198.1|dip:DIP-29165N|ensembl:ENSG00000099942(gene)|ensembl:ENST00000354336(transcript)|ensembl:ENST00000411769(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001568"(blood vessel development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001764"(neuron migration)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007416"(synapse assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016358"(dendrite development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035690"|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060465"(pharynx development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903977"(positive regulation of glial cell migration)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46109|rcsb pdb:2BZX|rcsb pdb:2BZY|rcsb pdb:2DBK|rcsb pdb:2EO3|rcsb pdb:2LQN|rcsb pdb:2LQW|reactome:R-HSA-170968|reactome:R-HSA-186763|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-9027284|reactome:R-HSA-912631	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:1YwlbUPPuijisz7AJM4Qkp7yJBI9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9NZM3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-308689|uniprotkb:O95062|uniprotkb:Q15812|uniprotkb:Q9HAK4|uniprotkb:Q9NXE6|uniprotkb:Q9NYG0|uniprotkb:Q9NZM2|uniprotkb:Q9ULG4|ensembl:ENSP00000347244	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:itsn2_human(display_long)|uniprotkb:ITSN2(gene name)|psi-mi:ITSN2(display_short)|uniprotkb:KIAA1256(gene name synonym)|uniprotkb:SH3D1B(gene name synonym)|uniprotkb:SWAP(gene name synonym)|uniprotkb:SH3 domain-containing protein 1B(gene name synonym)|uniprotkb:SH3P18(gene name synonym)|uniprotkb:SH3P18-like WASP-associated protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSP00000347244|ensembl:ENST00000361999|ensembl:ENSP00000354561|ensembl:ENST00000406921|ensembl:ENSP00000384499|ensembl:ENSG00000198399(gene)|ensembl:ENST00000355123(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0030154"(cell differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR027029|interpro:IPR035737|interpro:IPR035738|interpro:IPR035739|interpro:IPR035740|interpro:IPR035741|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|rcsb pdb:1J3T|rcsb pdb:1UDL|rcsb pdb:1UE9|rcsb pdb:1UFF|rcsb pdb:1UHF|rcsb pdb:3GF9|rcsb pdb:3JZY|rcsb pdb:4IIO|reactome:R-HSA-8856825|reactome:R-HSA-8856828|refseq:NP_006268.2|refseq:NP_062541.3|refseq:NP_671494.2	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:dxUqeWmW1uwOqgZ89UhT98/pt809606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B0LPF3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26518618	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b0lpf3_human(display_long)|uniprotkb:GRB2(gene name)|psi-mi:GRB2(display_short)|uniprotkb:hCG_27179(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007568"(aging)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|refseq:NP_002077.1|interpro:IPR035643|interpro:IPR035641|interpro:IPR000980(SH2 motif)|interpro:IPR036860|interpro:IPR036028|interpro:IPR001452(Src homology-3)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:SLnslQ7NHbnuK06nMVuRvJpoOA49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9UBC2	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-2556746|intact:EBI-28972990|ensembl:ENSP00000248070|uniprotkb:B4DKA3|uniprotkb:A2RRF3|uniprotkb:A5PL29	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:ep15r_human(display_long)|uniprotkb:EPS15R(gene name synonym)|uniprotkb:Eps15-related protein(gene name synonym)|uniprotkb:EPS15L1(gene name)|psi-mi:EPS15L1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_067058.1|ensembl:ENSP00000248070|ensembl:ENST00000455140|ensembl:ENSP00000393313|ensembl:ENST00000535753|ensembl:ENSP00000440103|ensembl:ENST00000597937|ensembl:ENSP00000472267|ensembl:ENST00000602022|ensembl:ENSP00000471981|ensembl:ENSG00000127527(gene)|ensembl:ENST00000248070(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0045296"(cadherin binding)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9UBC2|reactome:R-HSA-182971|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0030132"(clathrin coat of coated pit)|refseq:NP_001245303.1|refseq:NP_001245304.1|refseq:NP_001245305.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:6Bsao5czetxRxIiy3O/rZox4U+Y9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P13645	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-465144|ensembl:ENSP00000269576|uniprotkb:Q14664|uniprotkb:Q8N175	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:k1c10_human(display_long)|uniprotkb:KRT10(gene name)|psi-mi:KRT10(display_short)|uniprotkb:Cytokeratin-10(gene name synonym)|uniprotkb:KPP(gene name synonym)|uniprotkb:Keratin-10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000186395(gene)|ensembl:ENST00000269576(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P13645|rcsb pdb:3ASW|rcsb pdb:4F1Z|rcsb pdb:4ZRY|rcsb pdb:6E2J|rcsb pdb:6EC0|rcsb pdb:6UUI|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_000412.3	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:z100yyq3b63P0ARy2lE2ELyJeik9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P35527	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-356382|uniprotkb:O00109|uniprotkb:Q0IJ47|uniprotkb:Q14665|ensembl:ENSP00000246662	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:k1c9_human(display_long)|uniprotkb:KRT9(gene name)|psi-mi:KRT9(display_short)|uniprotkb:Keratin-9(gene name synonym)|uniprotkb:Cytokeratin-9(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_000217.2|ensembl:ENSG00000171403(gene)|ensembl:ENST00000246662(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0043588"(skin development)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P35527|reactome:R-HSA-6805567|reactome:R-HSA-6809371	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:m4EXfxbK2t1/EmI04YODKTJ02Zw9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P34932	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-356933|uniprotkb:O95756|uniprotkb:Q2TAL4|uniprotkb:Q9BUK9|ensembl:ENSP00000302961	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:hsp74_human(display_long)|uniprotkb:HSPA4(gene name)|psi-mi:HSPA4(display_short)|uniprotkb:APG2(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-2(gene name synonym)|uniprotkb:HSP70RY(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_002145.3|dip:DIP-460N|ensembl:ENSG00000170606(gene)|ensembl:ENST00000304858(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042052|interpro:IPR043129|mint:P34932|reactome:R-HSA-3371453	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:4OkTlG9p3IQQBYloiuHS8+t13TM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P55786	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1046129|uniprotkb:Q6P145|uniprotkb:Q9NP16|uniprotkb:Q9UEM2|ensembl:ENSP00000320324|ensembl:ENSP00000503682|uniprotkb:B7Z463	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:psa_human(display_long)|uniprotkb:NPEPPS(gene name)|psi-mi:NPEPPS(display_short)|uniprotkb:PSA(gene name synonym)|uniprotkb:Cytosol alanyl aminopeptidase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_006301.3|ensembl:ENSG00000141279(gene)|ensembl:ENST00000322157(transcript)|ensembl:ENST00000677120(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|reactome:R-HSA-983168|refseq:NP_001317186.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:gDl9SPlJhCOhA8uF4OEw+lIPh2M9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:F5H5D3	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-16421287|ensembl:ENSP00000443475	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:f5h5d3_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000167553(gene)|ensembl:ENST00000541364(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|refseq:NP_001290043.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:BPFi0oTuMH5kqvYU8ASeyTdB+y89606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9Y5K6	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-298152|uniprotkb:A6NL34|uniprotkb:Q5VYA3|uniprotkb:Q9UG97|ensembl:ENSP00000352264	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:cd2ap_human(display_long)|uniprotkb:CD2AP(gene name)|psi-mi:CD2AP(display_short)|uniprotkb:Cas ligand with multiple SH3 domains(gene name synonym)|uniprotkb:Adapter protein CMS(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000198087(gene)|ensembl:ENST00000359314(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031941"(filamentous actin)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR028445|interpro:IPR035775|interpro:IPR035776|interpro:IPR035777|interpro:IPR036028|mint:Q9Y5K6|rcsb pdb:2FEI|rcsb pdb:2J6F|rcsb pdb:2J6K|rcsb pdb:2J6O|rcsb pdb:2J7I|rcsb pdb:3AA6|rcsb pdb:3LK4|rcsb pdb:3U23|rcsb pdb:4WCI|rcsb pdb:4X1V|rcsb pdb:7DS6|rcsb pdb:7DS8|reactome:R-HSA-373753|refseq:NP_036252.1|dip:DIP-31807N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:T0OYMq1jOCwVMJOxnrPg5Jm4CGw9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P68363	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A024RAF0	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26518603	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a024raf0_human(display_long)|uniprotkb:BIN1(gene name)|psi-mi:BIN1(display_short)|uniprotkb:hCG_40441(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005829"(cytosol)|go:"GO:0030100"(regulation of endocytosis)|refseq:NP_647597.1|interpro:IPR027267|interpro:IPR003005(Amphiphysin)|interpro:IPR035471|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR036028|interpro:IPR001452(Src homology-3)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:pt689Cib8cYGArMk+0PU4BY5JpU9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:H6VRG1	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21356565	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:h6vrg1_human(display_long)|uniprotkb:KRT1(gene name)|psi-mi:KRT1(display_short)|uniprotkb:Keratin, type II cytoskeletal 1(gene name synonym)|uniprotkb:Keratin-1(gene name synonym)|uniprotkb:Type-II keratin Kb1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005886"(plasma membrane)|go:"GO:0045095"(keratin filament)|interpro:IPR018039|interpro:IPR039008|interpro:IPR032449|interpro:IPR032444|interpro:IPR003054(Type II keratin)|rcsb pdb:6EC0	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:+aTT3X4ok2allOQVrMpP7Alr/xE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P54652	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-356991|uniprotkb:Q15508|uniprotkb:Q53XM3|uniprotkb:Q9UE78|ensembl:ENSP00000247207|ensembl:ENSP00000378199	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:hsp72_human(display_long)|uniprotkb:HSPA2(gene name)|psi-mi:HSPA2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_068814.2|ensembl:ENSG00000126803(gene)|ensembl:ENST00000247207(transcript)|ensembl:ENST00000394709(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0036128"(CatSper complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0048156"(tau protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051861"(glycolipid binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P54652|rcsb pdb:3I33|rcsb pdb:4FSV|rcsb pdb:5FPD|rcsb pdb:5FPE|rcsb pdb:5FPM|rcsb pdb:5FPN|reactome:R-HSA-1221632|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:U+fdNfdxAWBQxDwSx0plk/iIBpM9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B2RAU5	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26518584	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b2rau5_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0035091"(phosphatidylinositol binding)|interpro:IPR027267|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR036028|interpro:IPR001452(Src homology-3)|interpro:IPR028644|interpro:IPR037425|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR037426|interpro:IPR035558|interpro:IPR019497	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:2A5AyIUy8pWJLZOGkx6K6LhYVI09606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P38646	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q13885	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-711595|ensembl:ENSP00000369703|uniprotkb:Q6FGZ8|uniprotkb:Q8IWR2	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:tbb2a_human(display_long)|uniprotkb:TUBB2A(gene name)|psi-mi:TUBB2A(display_short)|uniprotkb:TUBB2(gene name synonym)|uniprotkb:Tubulin beta class IIa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-389957|reactome:R-HSA-983189|reactome:R-HSA-9668328|ensembl:ENSG00000137267(gene)|ensembl:ENST00000333628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13885|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|refseq:NP_001060.1|refseq:NP_001297244.1	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P68371	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q9BVA1	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-355665|uniprotkb:A8K068|ensembl:ENSP00000259818	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:tbb2b_human(display_long)|uniprotkb:TUBB2B(gene name)|psi-mi:TUBB2B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_821080.1|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BVA1|rcsb pdb:6E7C|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|ensembl:ENST00000259818(transcript)|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-5663220|ensembl:ENSG00000137285(gene)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:sluQMryNuOvp6xlV558+agiRwvE9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P07437	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:V9HW22	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21351373	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:v9hw22_human(display_long)|uniprotkb:HEL-S-72p(gene name)|psi-mi:HEL-S-72p(display_short)|uniprotkb:HEL-33(gene name synonym)|uniprotkb:HSPA8(gene name synonym)|uniprotkb:hCG_2032950(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0072318"(clathrin coat disassembly)|refseq:NP_006588.1|refseq:XP_011541100.1|interpro:IPR018181|interpro:IPR029048|interpro:IPR029047|interpro:IPR013126(Heat shock protein 70)|interpro:IPR043129	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:B2R6X5	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-9977532	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:b2r6x5_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR018181|interpro:IPR029048|interpro:IPR029047|interpro:IPR013126(Heat shock protein 70)|interpro:IPR043129|go:"GO:0005524"(ATP binding)	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:PyOfve8bPEvlkK/XHYi4odRRMgU9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:V9HWB4	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21351661	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:v9hwb4_human(display_long)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:HEL-S-89n(gene name)|psi-mi:HEL-S-89n(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	interpro:IPR042050|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0035690"|go:"GO:0042220"(response to cocaine)|go:"GO:0001554"(luteolysis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:1901998"(toxin transport)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:0043022"(ribosome binding)|refseq:NP_005338.1|interpro:IPR018181|interpro:IPR029048|interpro:IPR029047|interpro:IPR013126(Heat shock protein 70)|interpro:IPR043129	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q96HY6	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1054024|uniprotkb:A6NIU5|uniprotkb:Q9BW47|uniprotkb:C9JSZ5|ensembl:ENSP00000346483	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:ddrgk_human(display_long)|uniprotkb:DDRGK1(gene name)|psi-mi:DDRGK1(display_short)|uniprotkb:C20orf116(gene name synonym)|uniprotkb:UFBP1(gene name synonym)|uniprotkb:UFM1-binding and PCI domain-containing protein 1(gene name synonym)|uniprotkb:Dashurin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_076424.1|ensembl:ENSG00000198171(gene)|ensembl:ENST00000354488(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061709"(reticulophagy)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0071569"(protein ufmylation)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1905050"(positive regulation of metallopeptidase activity)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990592"(protein K69-linked ufmylation)|interpro:IPR019153|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8980692	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:a34FmuGjW3zh9eliKvmntHGU6qw9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:P34931	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-354912|uniprotkb:O75634|uniprotkb:Q2HXR3|uniprotkb:Q8NE72|uniprotkb:A6NNB0|uniprotkb:Q96QC9|uniprotkb:Q9UQM1|uniprotkb:B0UXW8|ensembl:ENSP00000364805|ensembl:ENSP00000372881|ensembl:ENSP00000396486|ensembl:ENSP00000408347	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:hs71l_human(display_long)|uniprotkb:HSPA1L(gene name)|psi-mi:HSPA1L(display_short)|uniprotkb:Heat shock 70 kDa protein 1-Hom(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_005518.3|ensembl:ENSG00000204390(gene)|ensembl:ENSG00000206383(gene)|ensembl:ENSG00000234258(gene)|ensembl:ENSG00000236251(gene)|ensembl:ENST00000375654(transcript)|ensembl:ENST00000383390(transcript)|ensembl:ENST00000417601(transcript)|ensembl:ENST00000456772(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0072562"(blood microparticle)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P34931|rcsb pdb:3GDQ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:KS02DcMpD2sxSF36hUjKiSdYi4c9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:A0A0G2JIW1	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-21260251|ensembl:ENSP00000387691|ensembl:ENSP00000402651|ensembl:ENSP00000442789	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:a0a0g2jiw1_human(display_long)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000212866(gene)|ensembl:ENSG00000224501(gene)|ensembl:ENSG00000232804(gene)|ensembl:ENST00000417199(transcript)|ensembl:ENST00000458062(transcript)|ensembl:ENST00000545241(transcript)|go:"GO:0005524"(ATP binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:5xisCZbIBPDaoXx+UPWc9PdGmI09606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q6ZRC2	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-26518574	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:q6zrc2_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|refseq:NP_001306916.1|interpro:IPR000159(Ras-association)|interpro:IPR036860|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR037191	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:MDAdcevFLxVSSx5ZuepdN5a9jx49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:Q8TB24	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q8TB24	uniprotkb:O75792	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-9027352|uniprotkb:Q96F11|uniprotkb:B2RCY1|ensembl:ENSP00000221486	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:rnh2a_human(display_long)|uniprotkb:RNASEH2A(gene name)|psi-mi:RNASEH2A(display_short)|uniprotkb:Aicardi-Goutieres syndrome 4 protein(gene name synonym)|uniprotkb:RNASEHI(gene name synonym)|uniprotkb:RNHIA(gene name synonym)|uniprotkb:"RNase H(35)"(gene name synonym)|uniprotkb:Ribonuclease HI large subunit(gene name synonym)|uniprotkb:Ribonuclease HI subunit A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26518569|imex:IM-28480-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	refseq:NP_006388.2|ensembl:ENSG00000104889(gene)|ensembl:ENST00000221486(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006298"(mismatch repair)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0032299"(ribonuclease H2 complex)|go:"GO:0043137"(DNA replication, removal of RNA primer)|go:"GO:0046872"(metal ion binding)|interpro:IPR001352(Ribonuclease HII/HIII)|interpro:IPR004649(Ribonuclease HII)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR023160|interpro:IPR024567|interpro:IPR036397|rcsb pdb:3P56|rcsb pdb:3PUF	-	-	-	figure legend:Supplementary table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:UCK5FUsIvOKaNqxTiD2uRHyJ/ws9606	rigid:OZlgDY2UaCVuCWrqmq+MNSpXnfw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:O00499	uniprotkb:Q8TB24	intact:EBI-719094|uniprotkb:Q659B7|uniprotkb:O00297|uniprotkb:O00545|uniprotkb:O43867|uniprotkb:O60552|uniprotkb:O60553|uniprotkb:O60554|uniprotkb:O60555|uniprotkb:O75514|uniprotkb:O75515|uniprotkb:O75516|uniprotkb:O75517|uniprotkb:O75518|uniprotkb:Q92944|uniprotkb:Q99688|intact:EBI-1760307|intact:EBI-1965383|intact:EBI-28970933|ensembl:ENSP00000316779	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	psi-mi:bin1_human(display_long)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Box-dependent myc-interacting protein 1(gene name synonym)|uniprotkb:BIN1(gene name)|psi-mi:BIN1(display_short)|uniprotkb:AMPHL(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym)	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26520878|imex:IM-28480-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000259238|ensembl:ENSP00000259238|ensembl:ENSP00000316779|ensembl:ENST00000346226|ensembl:ENSP00000315411|ensembl:ENST00000348750|ensembl:ENSP00000259237|ensembl:ENST00000351659|ensembl:ENSP00000315388|ensembl:ENST00000352848|ensembl:ENSP00000315284|ensembl:ENST00000357970|ensembl:ENSP00000350654|ensembl:ENST00000376113|ensembl:ENSP00000365281|ensembl:ENST00000393040|ensembl:ENSP00000376760|ensembl:ENST00000393041|ensembl:ENSP00000376761|ensembl:ENST00000409400|ensembl:ENSP00000386797|refseq:NP_004296.1|refseq:NP_647593.1|refseq:NP_647594.1|refseq:NP_647595.1|refseq:NP_647596.1|refseq:NP_647597.1|refseq:NP_647598.1|refseq:NP_647599.1|refseq:NP_647600.1|refseq:NP_647601.1|refseq:NP_001307561.1|refseq:NP_001307562.1|refseq:NP_001307569.1|refseq:NP_001307570.1|refseq:NP_001307571.1|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|mint:O00499|rcsb pdb:1MUZ|rcsb pdb:1MV0|rcsb pdb:1MV3|rcsb pdb:2FIC|rcsb pdb:2RMY|rcsb pdb:2RND|rcsb pdb:5I22|reactome:R-HSA-8856828|go:"GO:0060987"(lipid tube)|ensembl:ENSG00000136717(gene)|ensembl:ENST00000316724(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006997"(nucleus organization)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030276"(clathrin binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048156"(tau protein binding)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|dip:DIP-41480N	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	-	-	-	figure legend:Fig. 3e|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:/3GFhR2reRqrmR19lWj5ErWP0N49606	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rigid:3IFnQCS7AQmZ9n5VxP0ji844e+8	false	flag tag:?-?	enhanced green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9Y5K6	uniprotkb:Q8TB24	intact:EBI-298152|uniprotkb:A6NL34|uniprotkb:Q5VYA3|uniprotkb:Q9UG97|ensembl:ENSP00000352264	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	psi-mi:cd2ap_human(display_long)|uniprotkb:CD2AP(gene name)|psi-mi:CD2AP(display_short)|uniprotkb:Cas ligand with multiple SH3 domains(gene name synonym)|uniprotkb:Adapter protein CMS(gene name synonym)	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26520920|imex:IM-28480-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198087(gene)|ensembl:ENST00000359314(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031941"(filamentous actin)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR028445|interpro:IPR035775|interpro:IPR035776|interpro:IPR035777|interpro:IPR036028|mint:Q9Y5K6|rcsb pdb:2FEI|rcsb pdb:2J6F|rcsb pdb:2J6K|rcsb pdb:2J6O|rcsb pdb:2J7I|rcsb pdb:3AA6|rcsb pdb:3LK4|rcsb pdb:3U23|rcsb pdb:4WCI|rcsb pdb:4X1V|rcsb pdb:7DS6|rcsb pdb:7DS8|reactome:R-HSA-373753|refseq:NP_036252.1|dip:DIP-31807N	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	-	-	-	figure legend:Fig. 3d|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/11/10	2020/12/10	rogid:T0OYMq1jOCwVMJOxnrPg5Jm4CGw9606	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rigid:vdwtDdBTTiGrO1EPZh6xJJ8GLL0	false	flag tag:?-?	enhanced green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8TB24	uniprotkb:O00499	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-719094|uniprotkb:Q659B7|uniprotkb:O00297|uniprotkb:O00545|uniprotkb:O43867|uniprotkb:O60552|uniprotkb:O60553|uniprotkb:O60554|uniprotkb:O60555|uniprotkb:O75514|uniprotkb:O75515|uniprotkb:O75516|uniprotkb:O75517|uniprotkb:O75518|uniprotkb:Q92944|uniprotkb:Q99688|intact:EBI-1760307|intact:EBI-1965383|intact:EBI-28970933|ensembl:ENSP00000316779	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:bin1_human(display_long)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Box-dependent myc-interacting protein 1(gene name synonym)|uniprotkb:BIN1(gene name)|psi-mi:BIN1(display_short)|uniprotkb:AMPHL(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26529583|imex:IM-28480-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENST00000259238|ensembl:ENSP00000259238|ensembl:ENSP00000316779|ensembl:ENST00000346226|ensembl:ENSP00000315411|ensembl:ENST00000348750|ensembl:ENSP00000259237|ensembl:ENST00000351659|ensembl:ENSP00000315388|ensembl:ENST00000352848|ensembl:ENSP00000315284|ensembl:ENST00000357970|ensembl:ENSP00000350654|ensembl:ENST00000376113|ensembl:ENSP00000365281|ensembl:ENST00000393040|ensembl:ENSP00000376760|ensembl:ENST00000393041|ensembl:ENSP00000376761|ensembl:ENST00000409400|ensembl:ENSP00000386797|refseq:NP_004296.1|refseq:NP_647593.1|refseq:NP_647594.1|refseq:NP_647595.1|refseq:NP_647596.1|refseq:NP_647597.1|refseq:NP_647598.1|refseq:NP_647599.1|refseq:NP_647600.1|refseq:NP_647601.1|refseq:NP_001307561.1|refseq:NP_001307562.1|refseq:NP_001307569.1|refseq:NP_001307570.1|refseq:NP_001307571.1|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|mint:O00499|rcsb pdb:1MUZ|rcsb pdb:1MV0|rcsb pdb:1MV3|rcsb pdb:2FIC|rcsb pdb:2RMY|rcsb pdb:2RND|rcsb pdb:5I22|reactome:R-HSA-8856828|go:"GO:0060987"(lipid tube)|ensembl:ENSG00000136717(gene)|ensembl:ENST00000316724(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006997"(nucleus organization)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030276"(clathrin binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048156"(tau protein binding)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|dip:DIP-41480N	-	-	-	figure legend:3F-I|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/11/10	2020/12/11	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:/3GFhR2reRqrmR19lWj5ErWP0N49606	rigid:3IFnQCS7AQmZ9n5VxP0ji844e+8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8TB24	uniprotkb:Q9Y5K6	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	intact:EBI-298152|uniprotkb:A6NL34|uniprotkb:Q5VYA3|uniprotkb:Q9UG97|ensembl:ENSP00000352264	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:cd2ap_human(display_long)|uniprotkb:CD2AP(gene name)|psi-mi:CD2AP(display_short)|uniprotkb:Cas ligand with multiple SH3 domains(gene name synonym)|uniprotkb:Adapter protein CMS(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26529820|imex:IM-28480-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	ensembl:ENSG00000198087(gene)|ensembl:ENST00000359314(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031941"(filamentous actin)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR028445|interpro:IPR035775|interpro:IPR035776|interpro:IPR035777|interpro:IPR036028|mint:Q9Y5K6|rcsb pdb:2FEI|rcsb pdb:2J6F|rcsb pdb:2J6K|rcsb pdb:2J6O|rcsb pdb:2J7I|rcsb pdb:3AA6|rcsb pdb:3LK4|rcsb pdb:3U23|rcsb pdb:4WCI|rcsb pdb:4X1V|rcsb pdb:7DS6|rcsb pdb:7DS8|reactome:R-HSA-373753|refseq:NP_036252.1|dip:DIP-31807N	-	-	-	figure legend:3F-II|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/11/10	2020/12/11	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rogid:T0OYMq1jOCwVMJOxnrPg5Jm4CGw9606	rigid:vdwtDdBTTiGrO1EPZh6xJJ8GLL0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:F1LRS8	uniprotkb:Q8TB24	intact:EBI-26530341|ensembl:ENSRNOP00000016291|uniprotkb:Q7TSS5	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	psi-mi:cd2ap_rat(display_long)|uniprotkb:Cd2ap(gene name)|psi-mi:Cd2ap(display_short)	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26529952|imex:IM-28480-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0051301"(cell division)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR028445|interpro:IPR035775|interpro:IPR035776|interpro:IPR035777|interpro:IPR036028|ensembl:ENSRNOG00000011987(gene)|ensembl:ENSRNOT00000016291(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016050"(vesicle organization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|rgd:727803	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0031982"(vesicle)	-	-	figure legend:Figs. 4a|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-pc12)|taxid:10116(Rattus norvegicus PC12 cells)	-	2020/11/10	2020/12/11	rogid:Gwb10CBBjBbDlTT51qZSnSqJKSA10116	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rigid:SeplPFgQZuCoQ+2WOUu7XQI0OA4	false	-	enhanced green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:O08839	uniprotkb:Q8TB24	intact:EBI-80095	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	psi-mi:bin1_rat(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:Amph2(gene name synonym)|uniprotkb:Amphl(gene name synonym)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym)	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26530475|imex:IM-28480-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005768"(endosome)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0043196"(varicosity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060987"(lipid tube)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|rcsb pdb:1BB9|reactome:R-RNO-8856828|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|rgd:621786|refseq:NP_446411.1|mint:O08839|dip:DIP-30979N	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0031982"(vesicle)	-	-	figure legend:Figs. 4b|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-pc12)|taxid:10116(Rattus norvegicus PC12 cells)	-	2020/11/10	2020/12/11	rogid:xqcXQWo+FXHjCGGI0Q9agaz9LMk10116	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rigid:TX5ng8d1yOVVgEQz61QLvTyqOZA	false	-	enhanced green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:O08539	uniprotkb:Q8TB24	intact:EBI-775152|uniprotkb:Q62434|ensembl:ENSMUSP00000025239	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	psi-mi:bin1_mouse(display_long)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:SH3 domain-containing protein 9(gene name synonym)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:Amphl(gene name synonym)|uniprotkb:Sh3p9(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym)	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26530667|imex:IM-28480-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033798.1|refseq:XP_006526056.1|ensembl:ENSMUSG00000024381(gene)|ensembl:ENSMUST00000025239(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0043196"(varicosity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060987"(lipid tube)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|mint:O08539|reactome:R-MMU-8856828	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0031982"(vesicle)	-	-	figure legend:Fig. 4d|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-neuron)|taxid:10090(Mus musculus neuronal cell)	-	2020/11/10	2020/12/11	rogid:VdFcKXTcbayNaahmrT13Dju7kLo10090	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rigid:ewEVIX1Vl+fgfWCkIz4GqRZSBdw	false	-	enhanced green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q9JLQ0	uniprotkb:Q8TB24	intact:EBI-644807|uniprotkb:E9QL86|uniprotkb:O88903|uniprotkb:Q8K4Z1|uniprotkb:Q8VCI9|ensembl:ENSMUSP00000024709	intact:EBI-1570523|uniprotkb:Q8NF30|uniprotkb:Q8TEE8|uniprotkb:Q8WYP4|uniprotkb:Q9H6A5|uniprotkb:Q9HAG1|uniprotkb:Q76LB3|ensembl:ENSP00000216487	psi-mi:cd2ap_mouse(display_long)|uniprotkb:Mesenchyme-to-epithelium transition protein with SH3 domains 1(gene name synonym)|uniprotkb:Cd2ap(gene name)|psi-mi:Cd2ap(display_short)|uniprotkb:Mets1(gene name synonym)	psi-mi:rin3_human(display_long)|uniprotkb:RIN3(gene name)|psi-mi:RIN3(display_short)|uniprotkb:Ras interaction/interference protein 3(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Shen et al. (2020)	pubmed:32552912|imex:IM-28480	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26530796|imex:IM-28480-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033977.3|ensembl:ENSMUSG00000061665(gene)|ensembl:ENSMUST00000024709(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016050"(vesicle organization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR028445|interpro:IPR035775|interpro:IPR035776|interpro:IPR035777|interpro:IPR036028|mint:Q9JLQ0|rcsb pdb:2JTE|rcsb pdb:2KRM|rcsb pdb:2KRN|rcsb pdb:2KRO|rcsb pdb:2LZ6|rcsb pdb:2MCN|go:"GO:1900182"(positive regulation of protein localization to nucleus)	refseq:NP_001306916.1|refseq:NP_079108.3|ensembl:ENSG00000100599(gene)|ensembl:ENST00000216487(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060755"(negative regulation of mast cell chemotaxis)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR035869|interpro:IPR036860|interpro:IPR037191|rcsb pdb:3U23|rcsb pdb:4WCI|reactome:R-HSA-8876198	go:"GO:0031982"(vesicle)	-	-	figure legend:Fig. 4c|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-neuron)|taxid:10090(Mus musculus neuronal cell)	-	2020/11/10	2020/12/11	rogid:siNa7wmze02HJhbUEEGxQaczJCQ10090	rogid:OoBIkofek2Ytk+FAw+dANFSfGl49606	rigid:wkd25x39JqdCwvhAgX7TiIzWdEw	false	-	enhanced green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0867"(tag visualisation by fluorescence)