#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:B0K022 uniprotkb:D3ZIM6 intact:EBI-25746441|ensembl:ENSRNOP00000026704|uniprotkb:F7FMT5 intact:EBI-25746485|ensembl:ENSRNOP00000025767|uniprotkb:B6ID12 psi-mi:b0k022_rat(display_long)|uniprotkb:Atp6v0b(gene name)|psi-mi:Atp6v0b(display_short)|uniprotkb:Atp6v0b_predicted(gene name synonym)|uniprotkb:rCG_50448(orf name) psi-mi:d3zim6_rat(display_long)|uniprotkb:Rnasek(gene name)|psi-mi:Rnasek(display_short) psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25745487|wwpdb:6VQ6|wwpdb:6VQ7|wwpdb:6VQ8|emdb:EMD-21317|emdb:EMD-21318|emdb:EMD-21319|imex:IM-28175-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000019655(gene)|ensembl:ENSRNOT00000026704(transcript)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|interpro:IPR026770|ensembl:ENSRNOG00000018881(gene)|ensembl:ENSRNOT00000025767(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0016021"(integral component of membrane)|rgd:1305687|refseq:NP_001131033.2 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1d, Fig S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:++BxirRe+rnqf1UfZgQ6FX5Df/010116 rogid:+csb9NhnCss6FcuBH6bLZRcU1SE10116 rigid:Gb9RN0AtgV7rosTOCXbF1jXENDw false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination)|psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:B0K022 uniprotkb:D4A133 intact:EBI-25746441|ensembl:ENSRNOP00000026704|uniprotkb:F7FMT5 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 psi-mi:b0k022_rat(display_long)|uniprotkb:Atp6v0b(gene name)|psi-mi:Atp6v0b(display_short)|uniprotkb:Atp6v0b_predicted(gene name synonym)|uniprotkb:rCG_50448(orf name) psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25745487|wwpdb:6VQ6|wwpdb:6VQ7|wwpdb:6VQ8|emdb:EMD-21317|emdb:EMD-21318|emdb:EMD-21319|imex:IM-28175-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000019655(gene)|ensembl:ENSRNOT00000026704(transcript)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1d, Fig S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:++BxirRe+rnqf1UfZgQ6FX5Df/010116 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rigid:Gb9RN0AtgV7rosTOCXbF1jXENDw false - - 1 3 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination)|psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:B0K022 uniprotkb:P25286-1 intact:EBI-25746441|ensembl:ENSRNOP00000026704|uniprotkb:F7FMT5 intact:EBI-25746350 psi-mi:b0k022_rat(display_long)|uniprotkb:Atp6v0b(gene name)|psi-mi:Atp6v0b(display_short)|uniprotkb:Atp6v0b_predicted(gene name synonym)|uniprotkb:rCG_50448(orf name) psi-mi:p25286-1(display_long)|uniprotkb:Atp6v0a1(gene name)|psi-mi:Atp6v0a1(display_short)|uniprotkb:Atp6n1(gene name synonym)|uniprotkb:Vpp1(gene name synonym)|uniprotkb:Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit(gene name synonym)|uniprotkb:Vacuolar adenosine triphosphatase subunit Ac116(gene name synonym)|uniprotkb:Vacuolar proton pump subunit 1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1(gene name synonym) psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25745487|wwpdb:6VQ6|wwpdb:6VQ7|wwpdb:6VQ8|emdb:EMD-21317|emdb:EMD-21318|emdb:EMD-21319|imex:IM-28175-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000019655(gene)|ensembl:ENSRNOT00000026704(transcript)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 intact:EBI-2024887(isoform-parent) wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1d, Fig S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:++BxirRe+rnqf1UfZgQ6FX5Df/010116 rogid:M+mzcb5KThafTTcJpimDmH5I4fk10116 rigid:Gb9RN0AtgV7rosTOCXbF1jXENDw false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination)|psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:B0K022 uniprotkb:Q5M7T6 intact:EBI-25746441|ensembl:ENSRNOP00000026704|uniprotkb:F7FMT5 intact:EBI-2113284|ensembl:ENSRNOP00000023606 psi-mi:b0k022_rat(display_long)|uniprotkb:Atp6v0b(gene name)|psi-mi:Atp6v0b(display_short)|uniprotkb:Atp6v0b_predicted(gene name synonym)|uniprotkb:rCG_50448(orf name) psi-mi:q5m7t6_rat(display_long)|uniprotkb:Atp6v0d1(gene name)|psi-mi:Atp6v0d1(display_short)|uniprotkb:rCG_51062(orf name) psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25745487|wwpdb:6VQ6|wwpdb:6VQ7|wwpdb:6VQ8|emdb:EMD-21317|emdb:EMD-21318|emdb:EMD-21319|imex:IM-28175-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000019655(gene)|ensembl:ENSRNOT00000026704(transcript)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 rgd:1306159|refseq:NP_001011927.1|ensembl:ENSRNOG00000017235(gene)|ensembl:ENSRNOT00000023606(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0005813"(centrosome)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0043005"(neuron projection)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR044911|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712|interpro:IPR036079 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1d, Fig S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:++BxirRe+rnqf1UfZgQ6FX5Df/010116 rogid:XxeN6m831kNCB989OtmNfbjUvlo10116 rigid:Gb9RN0AtgV7rosTOCXbF1jXENDw false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination)|psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:B0K022 uniprotkb:Q5ZWW6 intact:EBI-25746441|ensembl:ENSRNOP00000026704|uniprotkb:F7FMT5 intact:EBI-25746433|ensemblbacteria:AAU27055 psi-mi:b0k022_rat(display_long)|uniprotkb:Atp6v0b(gene name)|psi-mi:Atp6v0b(display_short)|uniprotkb:Atp6v0b_predicted(gene name synonym)|uniprotkb:rCG_50448(orf name) psi-mi:q5zww6_legph(display_long)|uniprotkb:lpg0968(locus name) psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25745487|wwpdb:6VQ6|wwpdb:6VQ7|wwpdb:6VQ8|emdb:EMD-21317|emdb:EMD-21318|emdb:EMD-21319|imex:IM-28175-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000019655(gene)|ensembl:ENSRNOT00000026704(transcript)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 ensemblbacteria:AAU27055(transcript)|ensemblbacteria:lpg0968(gene)|rcsb pdb:6WM3|rcsb pdb:6WLZ|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|refseq:WP_010946703.1|refseq:YP_095002.1|rcsb pdb:5UF5|rcsb pdb:5UFK wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1d, Fig S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:++BxirRe+rnqf1UfZgQ6FX5Df/010116 rogid:maU05b/1dYWTmFHe1GDptBEQTio272624 rigid:Gb9RN0AtgV7rosTOCXbF1jXENDw false - binding-associated region:1-278|flag tag:c-c 1 3 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)|psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:B0K022 uniprotkb:Q6P503 intact:EBI-25746441|ensembl:ENSRNOP00000026704|uniprotkb:F7FMT5 intact:EBI-918965|ensembl:ENSRNOP00000012101 psi-mi:b0k022_rat(display_long)|uniprotkb:Atp6v0b(gene name)|psi-mi:Atp6v0b(display_short)|uniprotkb:Atp6v0b_predicted(gene name synonym)|uniprotkb:rCG_50448(orf name) psi-mi:q6p503_rat(display_long)|uniprotkb:Atp6v1d(gene name)|psi-mi:Atp6v1d(display_short)|uniprotkb:V-type proton ATPase subunit d(gene name synonym)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym)|uniprotkb:rCG_61537(orf name) psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25745487|wwpdb:6VQ6|wwpdb:6VQ7|wwpdb:6VQ8|emdb:EMD-21317|emdb:EMD-21318|emdb:EMD-21319|imex:IM-28175-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000019655(gene)|ensembl:ENSRNOT00000026704(transcript)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 rgd:735119|refseq:NP_955418.1|ensembl:ENSRNOG00000009080(gene)|ensembl:ENSRNOT00000012101(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0016020"(membrane)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-6798695|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1d, Fig S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:++BxirRe+rnqf1UfZgQ6FX5Df/010116 rogid:hyYHJ3BMiHZ91ZBMo8Y2P3WETC410116 rigid:Gb9RN0AtgV7rosTOCXbF1jXENDw false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination)|psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:B0K022 uniprotkb:Q8R2H0 intact:EBI-25746441|ensembl:ENSRNOP00000026704|uniprotkb:F7FMT5 intact:EBI-25746386|ensembl:ENSRNOP00000001114 psi-mi:b0k022_rat(display_long)|uniprotkb:Atp6v0b(gene name)|psi-mi:Atp6v0b(display_short)|uniprotkb:Atp6v0b_predicted(gene name synonym)|uniprotkb:rCG_50448(orf name) psi-mi:q8r2h0_rat(display_long)|uniprotkb:Atp6v1g2(gene name)|psi-mi:Atp6v1g2(display_short)|uniprotkb:Aif1(gene name synonym)|uniprotkb:Bat1a(gene name synonym)|uniprotkb:Cdk2ap1-ps2(gene name synonym)|uniprotkb:Cdk2ap1-ps3(gene name synonym)|uniprotkb:Cdk2ap1-ps4(gene name synonym)|uniprotkb:Cdk2ap1-ps5(gene name synonym)|uniprotkb:Cdk2ap1-ps6(gene name synonym)|uniprotkb:E230034O05Rik(gene name synonym)|uniprotkb:LOC224733l-3(gene name synonym)|uniprotkb:LOC224733l-4(gene name synonym)|uniprotkb:LOC224733l-5(gene name synonym)|uniprotkb:LOC224733l-6(gene name synonym)|uniprotkb:LOC224733l-7(gene name synonym)|uniprotkb:LOC224733l-8(gene name synonym)|uniprotkb:Lst1(gene name synonym)|uniprotkb:RT1-CE12(gene name synonym)|uniprotkb:RT1-CE3(gene name synonym)|uniprotkb:RT1-CE5(gene name synonym)|uniprotkb:RT1-CE6(gene name synonym)|uniprotkb:RT1-CE8(gene name synonym)|uniprotkb:RT1-CE9(gene name synonym)|uniprotkb:Sacm2l-ps3(gene name synonym)|uniprotkb:Sacm2l-ps4(gene name synonym)|uniprotkb:Sacm2l-ps5(gene name synonym)|uniprotkb:Sacm2l-ps6(gene name synonym)|uniprotkb:Sacm2l-ps7(gene name synonym)|uniprotkb:Tnf(gene name synonym)|uniprotkb:rCG_38311(orf name) psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25745487|wwpdb:6VQ6|wwpdb:6VQ7|wwpdb:6VQ8|emdb:EMD-21317|emdb:EMD-21318|emdb:EMD-21319|imex:IM-28175-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000019655(gene)|ensembl:ENSRNOT00000026704(transcript)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 ensembl:ENSRNOG00000000840(gene)|ensembl:ENSRNOT00000001114(transcript)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR005124("Vacuolar (H+)-ATPase G subunit")|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|rcsb pdb:6VQI|rcsb pdb:6VQJ|rcsb pdb:6VQK|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712|rgd:1303186|refseq:NP_997655.1 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1d, Fig S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:++BxirRe+rnqf1UfZgQ6FX5Df/010116 rogid:Io9s6t7jqRyHwDR0fHjvHSKpkvM10116 rigid:Gb9RN0AtgV7rosTOCXbF1jXENDw false - - 1 3 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination)|psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:B0K022 uniprotkb:Q6AXS4 intact:EBI-25746441|ensembl:ENSRNOP00000026704|uniprotkb:F7FMT5 intact:EBI-25746497|ensembl:ENSRNOP00000005138 psi-mi:b0k022_rat(display_long)|uniprotkb:Atp6v0b(gene name)|psi-mi:Atp6v0b(display_short)|uniprotkb:Atp6v0b_predicted(gene name synonym)|uniprotkb:rCG_50448(orf name) psi-mi:renr_rat(display_long)|uniprotkb:Atp6ap2(gene name)|psi-mi:Atp6ap2(display_short)|uniprotkb:Atp6ip2(gene name synonym)|uniprotkb:"ATPase H(+)-transporting lysosomal accessory protein 2"(gene name synonym)|uniprotkb:"ATPase H(+)-transporting lysosomal-interacting protein 2"(gene name synonym)|uniprotkb:Renin/prorenin receptor(gene name synonym) psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25745487|wwpdb:6VQ6|wwpdb:6VQ7|wwpdb:6VQ8|emdb:EMD-21317|emdb:EMD-21318|emdb:EMD-21319|imex:IM-28175-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000019655(gene)|ensembl:ENSRNOT00000026704(transcript)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-2022377|reactome:R-RNO-6798695|rcsb pdb:6VQ8|ensembl:ENSRNOG00000003858(gene)|ensembl:ENSRNOT00000005138(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002003"(angiotensin maturation)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0021626"(central nervous system maturation)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030424"(axon)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032914"(positive regulation of transforming growth factor beta1 production)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048069"(eye pigmentation)|go:"GO:0060323"(head morphogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR012493(Renin receptor-like)|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rgd:1561269|refseq:NP_001007092.1 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1d, Fig S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:++BxirRe+rnqf1UfZgQ6FX5Df/010116 rogid:BvjIZh0X1FUF4gJSX8wzozjnBkQ10116 rigid:Gb9RN0AtgV7rosTOCXbF1jXENDw false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination)|psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:B0K022 uniprotkb:Q5EB76 intact:EBI-25746441|ensembl:ENSRNOP00000026704|uniprotkb:F7FMT5 intact:EBI-25746458|ensembl:ENSRNOP00000010853 psi-mi:b0k022_rat(display_long)|uniprotkb:Atp6v0b(gene name)|psi-mi:Atp6v0b(display_short)|uniprotkb:Atp6v0b_predicted(gene name synonym)|uniprotkb:rCG_50448(orf name) psi-mi:va0e2_rat(display_long)|uniprotkb:Atp6v0e2(gene name)|psi-mi:Atp6v0e2(display_short)|uniprotkb:Vacuolar proton pump subunit e 2(gene name synonym) psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25745487|wwpdb:6VQ6|wwpdb:6VQ7|wwpdb:6VQ8|emdb:EMD-21317|emdb:EMD-21318|emdb:EMD-21319|imex:IM-28175-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000019655(gene)|ensembl:ENSRNOT00000026704(transcript)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 ensembl:ENSRNOG00000008218(gene)|ensembl:ENSRNOT00000010853(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0055085"(transmembrane transport)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR008389(ATPase, V0 complex, subunit E)|interpro:IPR017385(ATPase, V0 complex, subunit E, metazoa)|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712|rgd:1303238|refseq:NP_001002253.1 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1d, Fig S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:++BxirRe+rnqf1UfZgQ6FX5Df/010116 rogid:A5itRj70z2kNZUrIkTLErNZN7Ao10116 rigid:Gb9RN0AtgV7rosTOCXbF1jXENDw false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination)|psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:B0K022 uniprotkb:O54715 intact:EBI-25746441|ensembl:ENSRNOP00000026704|uniprotkb:F7FMT5 intact:EBI-915573 psi-mi:b0k022_rat(display_long)|uniprotkb:Atp6v0b(gene name)|psi-mi:Atp6v0b(display_short)|uniprotkb:Atp6v0b_predicted(gene name synonym)|uniprotkb:rCG_50448(orf name) psi-mi:vas1_rat(display_long)|uniprotkb:V-ATPase S1 accessory protein(gene name synonym)|uniprotkb:V-ATPase Ac45 subunit(gene name synonym)|uniprotkb:C7-1 protein(gene name synonym)|uniprotkb:Atp6ap1(gene name)|psi-mi:Atp6ap1(display_short)|uniprotkb:Atp6ip1(gene name synonym)|uniprotkb:Atp6s1(gene name synonym)|uniprotkb:Vacuolar proton pump subunit S1(gene name synonym) psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25745487|wwpdb:6VQ6|wwpdb:6VQ7|wwpdb:6VQ8|emdb:EMD-21317|emdb:EMD-21318|emdb:EMD-21319|imex:IM-28175-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000019655(gene)|ensembl:ENSRNOT00000026704(transcript)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 interpro:IPR008388(ATPase, V1 complex, subunit S1)|rgd:620423|refseq:NP_113973.1|mint:O54715|go:"GO:0005524"(ATP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007568"(aging)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033180"(proton-transporting V-type ATPase, V1 domain)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045851"(pH reduction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:2001206"(positive regulation of osteoclast development)|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-77387|reactome:R-RNO-8980692|reactome:R-RNO-917977|reactome:R-RNO-983712 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1d, Fig S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:++BxirRe+rnqf1UfZgQ6FX5Df/010116 rogid:SQbhwQxTt+SDeOiaf5IuR0kMVHU10116 rigid:Gb9RN0AtgV7rosTOCXbF1jXENDw false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination)|psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:B0K022 uniprotkb:P62815 intact:EBI-25746441|ensembl:ENSRNOP00000026704|uniprotkb:F7FMT5 intact:EBI-772667|uniprotkb:O09045|uniprotkb:P50517|ensembl:ENSRNOP00000015931 psi-mi:b0k022_rat(display_long)|uniprotkb:Atp6v0b(gene name)|psi-mi:Atp6v0b(display_short)|uniprotkb:Atp6v0b_predicted(gene name synonym)|uniprotkb:rCG_50448(orf name) psi-mi:vatb2_rat(display_long)|uniprotkb:Vacuolar proton pump subunit B 2(gene name synonym)|uniprotkb:Endomembrane proton pump 58 kDa subunit(gene name synonym)|uniprotkb:Atp6v1b2(gene name)|psi-mi:Atp6v1b2(display_short)|uniprotkb:Atp6b2(gene name synonym)|uniprotkb:Vat2(gene name synonym) psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25745487|wwpdb:6VQ6|wwpdb:6VQ7|wwpdb:6VQ8|emdb:EMD-21317|emdb:EMD-21318|emdb:EMD-21319|imex:IM-28175-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000019655(gene)|ensembl:ENSRNOT00000026704(transcript)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 rgd:620284|refseq:NP_476561.1|ensembl:ENSRNOG00000011891(gene)|ensembl:ENSRNOT00000015931(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0001726"(ruffle)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0042470"(melanosome)|go:"GO:0046034"(ATP metabolic process)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005723(ATPase, V1 complex, subunit B)|interpro:IPR020003|interpro:IPR022879|interpro:IPR027417|mint:P62815|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1d, Fig S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:++BxirRe+rnqf1UfZgQ6FX5Df/010116 rogid:cmFm/xe3iOTqmy849cfoi4XeG+A10116 rigid:Gb9RN0AtgV7rosTOCXbF1jXENDw false - - 1 3 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination)|psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:B0K022 uniprotkb:Q5FVI6 intact:EBI-25746441|ensembl:ENSRNOP00000026704|uniprotkb:F7FMT5 intact:EBI-25746358|ensembl:ENSRNOP00000006917 psi-mi:b0k022_rat(display_long)|uniprotkb:Atp6v0b(gene name)|psi-mi:Atp6v0b(display_short)|uniprotkb:Atp6v0b_predicted(gene name synonym)|uniprotkb:rCG_50448(orf name) psi-mi:vatc1_rat(display_long)|uniprotkb:Atp6v1c1(gene name)|psi-mi:Atp6v1c1(display_short)|uniprotkb:Vacuolar proton pump subunit C 1(gene name synonym) psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25745487|wwpdb:6VQ6|wwpdb:6VQ7|wwpdb:6VQ8|emdb:EMD-21317|emdb:EMD-21318|emdb:EMD-21319|imex:IM-28175-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000019655(gene)|ensembl:ENSRNOT00000026704(transcript)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 ensembl:ENSRNOG00000004846(gene)|ensembl:ENSRNOT00000006917(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045177"(apical part of cell)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004907(ATPase, V1 complex, subunit C)|interpro:IPR036132|rcsb pdb:6VQ6|rcsb pdb:6VQ8|rcsb pdb:6VQI|rcsb pdb:6VQJ|rcsb pdb:6VQK|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712|rcsb pdb:6VQ7|rgd:1311082|refseq:NP_001011992.1 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1d, Fig S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:++BxirRe+rnqf1UfZgQ6FX5Df/010116 rogid:2XM+bnhDWDTYiyEu8uxyqYSmhSc10116 rigid:Gb9RN0AtgV7rosTOCXbF1jXENDw false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination)|psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:B0K022 uniprotkb:Q6PCU2 intact:EBI-25746441|ensembl:ENSRNOP00000026704|uniprotkb:F7FMT5 intact:EBI-919161 psi-mi:b0k022_rat(display_long)|uniprotkb:Atp6v0b(gene name)|psi-mi:Atp6v0b(display_short)|uniprotkb:Atp6v0b_predicted(gene name synonym)|uniprotkb:rCG_50448(orf name) psi-mi:vate1_rat(display_long)|uniprotkb:Atp6v1e1(gene name)|psi-mi:Atp6v1e1(display_short)|uniprotkb:Vacuolar proton pump subunit E 1(gene name synonym) psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25745487|wwpdb:6VQ6|wwpdb:6VQ7|wwpdb:6VQ8|emdb:EMD-21317|emdb:EMD-21318|emdb:EMD-21319|imex:IM-28175-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000019655(gene)|ensembl:ENSRNOT00000026704(transcript)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 rgd:735157|refseq:NP_942040.1|interpro:IPR002842(ATPase, V1/A1 complex, subunit E)|mint:Q6PCU2|interpro:IPR038495|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:1902600"(proton transmembrane transport)|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|rcsb pdb:6VQI|rcsb pdb:6VQJ|rcsb pdb:6VQK|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1d, Fig S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:++BxirRe+rnqf1UfZgQ6FX5Df/010116 rogid:mfYO92S6Lf0DGuQmxSaUAoCmQcw10116 rigid:Gb9RN0AtgV7rosTOCXbF1jXENDw false - - 1 3 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination)|psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:B0K022 uniprotkb:P50408 intact:EBI-25746441|ensembl:ENSRNOP00000026704|uniprotkb:F7FMT5 intact:EBI-917679|ensembl:ENSRNOP00000009737 psi-mi:b0k022_rat(display_long)|uniprotkb:Atp6v0b(gene name)|psi-mi:Atp6v0b(display_short)|uniprotkb:Atp6v0b_predicted(gene name synonym)|uniprotkb:rCG_50448(orf name) psi-mi:vatf_rat(display_long)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym)|uniprotkb:Atp6v1f(gene name)|psi-mi:Atp6v1f(display_short)|uniprotkb:Atp6s14(gene name synonym)|uniprotkb:Vatf(gene name synonym) psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25745487|wwpdb:6VQ6|wwpdb:6VQ7|wwpdb:6VQ8|emdb:EMD-21317|emdb:EMD-21318|emdb:EMD-21319|imex:IM-28175-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000019655(gene)|ensembl:ENSRNOT00000026704(transcript)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 ensembl:ENSRNOG00000007392(gene)|ensembl:ENSRNOT00000009737(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033180"(proton-transporting V-type ATPase, V1 domain)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rgd:621552|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712|refseq:NP_446336.1 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1d, Fig S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:++BxirRe+rnqf1UfZgQ6FX5Df/010116 rogid:3fcGzehnyb0ieULlCF2CLvnmUhc10116 rigid:Gb9RN0AtgV7rosTOCXbF1jXENDw false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination)|psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:B0K022 uniprotkb:P63081 intact:EBI-25746441|ensembl:ENSRNOP00000026704|uniprotkb:F7FMT5 intact:EBI-2025009|uniprotkb:P23967|ensembl:ENSRNOP00000008736 psi-mi:b0k022_rat(display_long)|uniprotkb:Atp6v0b(gene name)|psi-mi:Atp6v0b(display_short)|uniprotkb:Atp6v0b_predicted(gene name synonym)|uniprotkb:rCG_50448(orf name) psi-mi:vatl_rat(display_long)|uniprotkb:Atp6v0c(gene name)|psi-mi:Atp6v0c(display_short)|uniprotkb:Atp6c(gene name synonym)|uniprotkb:Atp6l(gene name synonym)|uniprotkb:Atpl(gene name synonym)|uniprotkb:Vacuolar proton pump 16 kDa proteolipid subunit(gene name synonym) psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25745487|wwpdb:6VQ6|wwpdb:6VQ7|wwpdb:6VQ8|emdb:EMD-21317|emdb:EMD-21318|emdb:EMD-21319|imex:IM-28175-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000019655(gene)|ensembl:ENSRNOT00000026704(transcript)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 rgd:621394|refseq:NP_570836.1|refseq:XP_006245960.1|ensembl:ENSRNOG00000006542(gene)|ensembl:ENSRNOT00000008736(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1904093"(negative regulation of autophagic cell death)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR011555(ATPase, V0 complex, proteolipid subunit C, eukaryotic)|interpro:IPR035921|mint:P63081|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-6798695|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1d, Fig S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:++BxirRe+rnqf1UfZgQ6FX5Df/010116 rogid:Qx4BtXXIXdTlTTWE3nBHM8kThHU10116 rigid:Gb9RN0AtgV7rosTOCXbF1jXENDw false - - 1 16 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination)|psi-mi:"MI:0708"(monoclonal antibody immunostaining) uniprotkb:D4A133 uniprotkb:Q5ZWW6 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 intact:EBI-25746433|ensemblbacteria:AAU27055 psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:q5zww6_legph(display_long)|uniprotkb:lpg0968(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25746587|imex:IM-28175-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 ensemblbacteria:AAU27055(transcript)|ensemblbacteria:lpg0968(gene)|rcsb pdb:6WM3|rcsb pdb:6WLZ|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|refseq:WP_010946703.1|refseq:YP_095002.1|rcsb pdb:5UF5|rcsb pdb:5UFK wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rogid:maU05b/1dYWTmFHe1GDptBEQTio272624 rigid:jJ1491Wv6IJNmz0zUTwYoEYq87k false - binding-associated region:1-278|flag tag:c-c 3 3 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:D4A133 uniprotkb:Q6P503 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 intact:EBI-918965|ensembl:ENSRNOP00000012101 psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:q6p503_rat(display_long)|uniprotkb:Atp6v1d(gene name)|psi-mi:Atp6v1d(display_short)|uniprotkb:V-type proton ATPase subunit d(gene name synonym)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym)|uniprotkb:rCG_61537(orf name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25746587|imex:IM-28175-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 rgd:735119|refseq:NP_955418.1|ensembl:ENSRNOG00000009080(gene)|ensembl:ENSRNOT00000012101(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0016020"(membrane)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-6798695|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rogid:hyYHJ3BMiHZ91ZBMo8Y2P3WETC410116 rigid:jJ1491Wv6IJNmz0zUTwYoEYq87k false - - 3 1 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:D4A133 uniprotkb:Q8R2H0 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 intact:EBI-25746386|ensembl:ENSRNOP00000001114 psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:q8r2h0_rat(display_long)|uniprotkb:Atp6v1g2(gene name)|psi-mi:Atp6v1g2(display_short)|uniprotkb:Aif1(gene name synonym)|uniprotkb:Bat1a(gene name synonym)|uniprotkb:Cdk2ap1-ps2(gene name synonym)|uniprotkb:Cdk2ap1-ps3(gene name synonym)|uniprotkb:Cdk2ap1-ps4(gene name synonym)|uniprotkb:Cdk2ap1-ps5(gene name synonym)|uniprotkb:Cdk2ap1-ps6(gene name synonym)|uniprotkb:E230034O05Rik(gene name synonym)|uniprotkb:LOC224733l-3(gene name synonym)|uniprotkb:LOC224733l-4(gene name synonym)|uniprotkb:LOC224733l-5(gene name synonym)|uniprotkb:LOC224733l-6(gene name synonym)|uniprotkb:LOC224733l-7(gene name synonym)|uniprotkb:LOC224733l-8(gene name synonym)|uniprotkb:Lst1(gene name synonym)|uniprotkb:RT1-CE12(gene name synonym)|uniprotkb:RT1-CE3(gene name synonym)|uniprotkb:RT1-CE5(gene name synonym)|uniprotkb:RT1-CE6(gene name synonym)|uniprotkb:RT1-CE8(gene name synonym)|uniprotkb:RT1-CE9(gene name synonym)|uniprotkb:Sacm2l-ps3(gene name synonym)|uniprotkb:Sacm2l-ps4(gene name synonym)|uniprotkb:Sacm2l-ps5(gene name synonym)|uniprotkb:Sacm2l-ps6(gene name synonym)|uniprotkb:Sacm2l-ps7(gene name synonym)|uniprotkb:Tnf(gene name synonym)|uniprotkb:rCG_38311(orf name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25746587|imex:IM-28175-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 ensembl:ENSRNOG00000000840(gene)|ensembl:ENSRNOT00000001114(transcript)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR005124("Vacuolar (H+)-ATPase G subunit")|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|rcsb pdb:6VQI|rcsb pdb:6VQJ|rcsb pdb:6VQK|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712|rgd:1303186|refseq:NP_997655.1 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rogid:Io9s6t7jqRyHwDR0fHjvHSKpkvM10116 rigid:jJ1491Wv6IJNmz0zUTwYoEYq87k false - - 3 3 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:D4A133 uniprotkb:P62815 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 intact:EBI-772667|uniprotkb:O09045|uniprotkb:P50517|ensembl:ENSRNOP00000015931 psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:vatb2_rat(display_long)|uniprotkb:Vacuolar proton pump subunit B 2(gene name synonym)|uniprotkb:Endomembrane proton pump 58 kDa subunit(gene name synonym)|uniprotkb:Atp6v1b2(gene name)|psi-mi:Atp6v1b2(display_short)|uniprotkb:Atp6b2(gene name synonym)|uniprotkb:Vat2(gene name synonym) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25746587|imex:IM-28175-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 rgd:620284|refseq:NP_476561.1|ensembl:ENSRNOG00000011891(gene)|ensembl:ENSRNOT00000015931(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0001726"(ruffle)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0042470"(melanosome)|go:"GO:0046034"(ATP metabolic process)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005723(ATPase, V1 complex, subunit B)|interpro:IPR020003|interpro:IPR022879|interpro:IPR027417|mint:P62815|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rogid:cmFm/xe3iOTqmy849cfoi4XeG+A10116 rigid:jJ1491Wv6IJNmz0zUTwYoEYq87k false - - 3 3 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:D4A133 uniprotkb:Q5FVI6 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 intact:EBI-25746358|ensembl:ENSRNOP00000006917 psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:vatc1_rat(display_long)|uniprotkb:Atp6v1c1(gene name)|psi-mi:Atp6v1c1(display_short)|uniprotkb:Vacuolar proton pump subunit C 1(gene name synonym) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25746587|imex:IM-28175-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 ensembl:ENSRNOG00000004846(gene)|ensembl:ENSRNOT00000006917(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045177"(apical part of cell)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004907(ATPase, V1 complex, subunit C)|interpro:IPR036132|rcsb pdb:6VQ6|rcsb pdb:6VQ8|rcsb pdb:6VQI|rcsb pdb:6VQJ|rcsb pdb:6VQK|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712|rcsb pdb:6VQ7|rgd:1311082|refseq:NP_001011992.1 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rogid:2XM+bnhDWDTYiyEu8uxyqYSmhSc10116 rigid:jJ1491Wv6IJNmz0zUTwYoEYq87k false - - 3 1 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:D4A133 uniprotkb:Q6PCU2 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 intact:EBI-919161 psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:vate1_rat(display_long)|uniprotkb:Atp6v1e1(gene name)|psi-mi:Atp6v1e1(display_short)|uniprotkb:Vacuolar proton pump subunit E 1(gene name synonym) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25746587|imex:IM-28175-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 rgd:735157|refseq:NP_942040.1|interpro:IPR002842(ATPase, V1/A1 complex, subunit E)|mint:Q6PCU2|interpro:IPR038495|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:1902600"(proton transmembrane transport)|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|rcsb pdb:6VQI|rcsb pdb:6VQJ|rcsb pdb:6VQK|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rogid:mfYO92S6Lf0DGuQmxSaUAoCmQcw10116 rigid:jJ1491Wv6IJNmz0zUTwYoEYq87k false - - 3 3 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:D4A133 uniprotkb:P50408 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 intact:EBI-917679|ensembl:ENSRNOP00000009737 psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:vatf_rat(display_long)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym)|uniprotkb:Atp6v1f(gene name)|psi-mi:Atp6v1f(display_short)|uniprotkb:Atp6s14(gene name synonym)|uniprotkb:Vatf(gene name synonym) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25746587|imex:IM-28175-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 ensembl:ENSRNOG00000007392(gene)|ensembl:ENSRNOT00000009737(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033180"(proton-transporting V-type ATPase, V1 domain)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rgd:621552|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712|refseq:NP_446336.1 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rogid:3fcGzehnyb0ieULlCF2CLvnmUhc10116 rigid:jJ1491Wv6IJNmz0zUTwYoEYq87k false - - 3 1 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q5ZWW6 uniprotkb:D4A133 intact:EBI-25746433|ensemblbacteria:AAU27055 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 psi-mi:q5zww6_legph(display_long)|uniprotkb:lpg0968(locus name) psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25746627|imex:IM-28175-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAU27055(transcript)|ensemblbacteria:lpg0968(gene)|rcsb pdb:6WM3|rcsb pdb:6WLZ|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|refseq:WP_010946703.1|refseq:YP_095002.1|rcsb pdb:5UF5|rcsb pdb:5UFK rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:maU05b/1dYWTmFHe1GDptBEQTio272624 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rigid:64Q0aa5KptB4xIuns6KAus0WbRM false binding-associated region:1-278|flag tag:c-c - 1 1 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:D4A133 uniprotkb:Q5ZWW6 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 intact:EBI-25746433|ensemblbacteria:AAU27055 psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:q5zww6_legph(display_long)|uniprotkb:lpg0968(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25746661|imex:IM-28175-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 ensemblbacteria:AAU27055(transcript)|ensemblbacteria:lpg0968(gene)|rcsb pdb:6WM3|rcsb pdb:6WLZ|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|refseq:WP_010946703.1|refseq:YP_095002.1|rcsb pdb:5UF5|rcsb pdb:5UFK wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rogid:maU05b/1dYWTmFHe1GDptBEQTio272624 rigid:jJ1491Wv6IJNmz0zUTwYoEYq87k false - binding-associated region:1-278|flag tag:c-c 3 3 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:D4A133 uniprotkb:Q6P503 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 intact:EBI-918965|ensembl:ENSRNOP00000012101 psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:q6p503_rat(display_long)|uniprotkb:Atp6v1d(gene name)|psi-mi:Atp6v1d(display_short)|uniprotkb:V-type proton ATPase subunit d(gene name synonym)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym)|uniprotkb:rCG_61537(orf name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25746661|imex:IM-28175-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 rgd:735119|refseq:NP_955418.1|ensembl:ENSRNOG00000009080(gene)|ensembl:ENSRNOT00000012101(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0016020"(membrane)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-6798695|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rogid:hyYHJ3BMiHZ91ZBMo8Y2P3WETC410116 rigid:jJ1491Wv6IJNmz0zUTwYoEYq87k false - - 3 1 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:D4A133 uniprotkb:Q8R2H0 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 intact:EBI-25746386|ensembl:ENSRNOP00000001114 psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:q8r2h0_rat(display_long)|uniprotkb:Atp6v1g2(gene name)|psi-mi:Atp6v1g2(display_short)|uniprotkb:Aif1(gene name synonym)|uniprotkb:Bat1a(gene name synonym)|uniprotkb:Cdk2ap1-ps2(gene name synonym)|uniprotkb:Cdk2ap1-ps3(gene name synonym)|uniprotkb:Cdk2ap1-ps4(gene name synonym)|uniprotkb:Cdk2ap1-ps5(gene name synonym)|uniprotkb:Cdk2ap1-ps6(gene name synonym)|uniprotkb:E230034O05Rik(gene name synonym)|uniprotkb:LOC224733l-3(gene name synonym)|uniprotkb:LOC224733l-4(gene name synonym)|uniprotkb:LOC224733l-5(gene name synonym)|uniprotkb:LOC224733l-6(gene name synonym)|uniprotkb:LOC224733l-7(gene name synonym)|uniprotkb:LOC224733l-8(gene name synonym)|uniprotkb:Lst1(gene name synonym)|uniprotkb:RT1-CE12(gene name synonym)|uniprotkb:RT1-CE3(gene name synonym)|uniprotkb:RT1-CE5(gene name synonym)|uniprotkb:RT1-CE6(gene name synonym)|uniprotkb:RT1-CE8(gene name synonym)|uniprotkb:RT1-CE9(gene name synonym)|uniprotkb:Sacm2l-ps3(gene name synonym)|uniprotkb:Sacm2l-ps4(gene name synonym)|uniprotkb:Sacm2l-ps5(gene name synonym)|uniprotkb:Sacm2l-ps6(gene name synonym)|uniprotkb:Sacm2l-ps7(gene name synonym)|uniprotkb:Tnf(gene name synonym)|uniprotkb:rCG_38311(orf name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25746661|imex:IM-28175-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 ensembl:ENSRNOG00000000840(gene)|ensembl:ENSRNOT00000001114(transcript)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR005124("Vacuolar (H+)-ATPase G subunit")|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|rcsb pdb:6VQI|rcsb pdb:6VQJ|rcsb pdb:6VQK|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712|rgd:1303186|refseq:NP_997655.1 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rogid:Io9s6t7jqRyHwDR0fHjvHSKpkvM10116 rigid:jJ1491Wv6IJNmz0zUTwYoEYq87k false - - 3 3 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:D4A133 uniprotkb:P62815 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 intact:EBI-772667|uniprotkb:O09045|uniprotkb:P50517|ensembl:ENSRNOP00000015931 psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:vatb2_rat(display_long)|uniprotkb:Vacuolar proton pump subunit B 2(gene name synonym)|uniprotkb:Endomembrane proton pump 58 kDa subunit(gene name synonym)|uniprotkb:Atp6v1b2(gene name)|psi-mi:Atp6v1b2(display_short)|uniprotkb:Atp6b2(gene name synonym)|uniprotkb:Vat2(gene name synonym) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25746661|imex:IM-28175-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 rgd:620284|refseq:NP_476561.1|ensembl:ENSRNOG00000011891(gene)|ensembl:ENSRNOT00000015931(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0001726"(ruffle)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0042470"(melanosome)|go:"GO:0046034"(ATP metabolic process)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005723(ATPase, V1 complex, subunit B)|interpro:IPR020003|interpro:IPR022879|interpro:IPR027417|mint:P62815|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rogid:cmFm/xe3iOTqmy849cfoi4XeG+A10116 rigid:jJ1491Wv6IJNmz0zUTwYoEYq87k false - - 3 3 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:D4A133 uniprotkb:Q5FVI6 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 intact:EBI-25746358|ensembl:ENSRNOP00000006917 psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:vatc1_rat(display_long)|uniprotkb:Atp6v1c1(gene name)|psi-mi:Atp6v1c1(display_short)|uniprotkb:Vacuolar proton pump subunit C 1(gene name synonym) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25746661|imex:IM-28175-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 ensembl:ENSRNOG00000004846(gene)|ensembl:ENSRNOT00000006917(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045177"(apical part of cell)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004907(ATPase, V1 complex, subunit C)|interpro:IPR036132|rcsb pdb:6VQ6|rcsb pdb:6VQ8|rcsb pdb:6VQI|rcsb pdb:6VQJ|rcsb pdb:6VQK|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712|rcsb pdb:6VQ7|rgd:1311082|refseq:NP_001011992.1 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rogid:2XM+bnhDWDTYiyEu8uxyqYSmhSc10116 rigid:jJ1491Wv6IJNmz0zUTwYoEYq87k false - - 3 2 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:D4A133 uniprotkb:Q6PCU2 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 intact:EBI-919161 psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:vate1_rat(display_long)|uniprotkb:Atp6v1e1(gene name)|psi-mi:Atp6v1e1(display_short)|uniprotkb:Vacuolar proton pump subunit E 1(gene name synonym) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25746661|imex:IM-28175-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 rgd:735157|refseq:NP_942040.1|interpro:IPR002842(ATPase, V1/A1 complex, subunit E)|mint:Q6PCU2|interpro:IPR038495|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:1902600"(proton transmembrane transport)|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|rcsb pdb:6VQI|rcsb pdb:6VQJ|rcsb pdb:6VQK|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rogid:mfYO92S6Lf0DGuQmxSaUAoCmQcw10116 rigid:jJ1491Wv6IJNmz0zUTwYoEYq87k false - - 3 3 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:D4A133 uniprotkb:P50408 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 intact:EBI-917679|ensembl:ENSRNOP00000009737 psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:vatf_rat(display_long)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym)|uniprotkb:Atp6v1f(gene name)|psi-mi:Atp6v1f(display_short)|uniprotkb:Atp6s14(gene name synonym)|uniprotkb:Vatf(gene name synonym) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25746661|imex:IM-28175-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 ensembl:ENSRNOG00000007392(gene)|ensembl:ENSRNOT00000009737(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033180"(proton-transporting V-type ATPase, V1 domain)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rgd:621552|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712|refseq:NP_446336.1 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rogid:3fcGzehnyb0ieULlCF2CLvnmUhc10116 rigid:jJ1491Wv6IJNmz0zUTwYoEYq87k false - - 3 1 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:D4A133 uniprotkb:Q5ZWW6 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 intact:EBI-25746433|ensemblbacteria:AAU27055 psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:q5zww6_legph(display_long)|uniprotkb:lpg0968(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25746693|imex:IM-28175-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 ensemblbacteria:AAU27055(transcript)|ensemblbacteria:lpg0968(gene)|rcsb pdb:6WM3|rcsb pdb:6WLZ|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|refseq:WP_010946703.1|refseq:YP_095002.1|rcsb pdb:5UF5|rcsb pdb:5UFK wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rogid:maU05b/1dYWTmFHe1GDptBEQTio272624 rigid:FyI5aY3/KDjTYGK8vcF17qifI+0 false - binding-associated region:1-278|flag tag:c-c 3 3 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:D4A133 uniprotkb:Q6P503 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 intact:EBI-918965|ensembl:ENSRNOP00000012101 psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:q6p503_rat(display_long)|uniprotkb:Atp6v1d(gene name)|psi-mi:Atp6v1d(display_short)|uniprotkb:V-type proton ATPase subunit d(gene name synonym)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym)|uniprotkb:rCG_61537(orf name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25746693|imex:IM-28175-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 rgd:735119|refseq:NP_955418.1|ensembl:ENSRNOG00000009080(gene)|ensembl:ENSRNOT00000012101(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0016020"(membrane)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-6798695|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rogid:hyYHJ3BMiHZ91ZBMo8Y2P3WETC410116 rigid:FyI5aY3/KDjTYGK8vcF17qifI+0 false - - 3 1 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:D4A133 uniprotkb:Q8R2H0 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 intact:EBI-25746386|ensembl:ENSRNOP00000001114 psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:q8r2h0_rat(display_long)|uniprotkb:Atp6v1g2(gene name)|psi-mi:Atp6v1g2(display_short)|uniprotkb:Aif1(gene name synonym)|uniprotkb:Bat1a(gene name synonym)|uniprotkb:Cdk2ap1-ps2(gene name synonym)|uniprotkb:Cdk2ap1-ps3(gene name synonym)|uniprotkb:Cdk2ap1-ps4(gene name synonym)|uniprotkb:Cdk2ap1-ps5(gene name synonym)|uniprotkb:Cdk2ap1-ps6(gene name synonym)|uniprotkb:E230034O05Rik(gene name synonym)|uniprotkb:LOC224733l-3(gene name synonym)|uniprotkb:LOC224733l-4(gene name synonym)|uniprotkb:LOC224733l-5(gene name synonym)|uniprotkb:LOC224733l-6(gene name synonym)|uniprotkb:LOC224733l-7(gene name synonym)|uniprotkb:LOC224733l-8(gene name synonym)|uniprotkb:Lst1(gene name synonym)|uniprotkb:RT1-CE12(gene name synonym)|uniprotkb:RT1-CE3(gene name synonym)|uniprotkb:RT1-CE5(gene name synonym)|uniprotkb:RT1-CE6(gene name synonym)|uniprotkb:RT1-CE8(gene name synonym)|uniprotkb:RT1-CE9(gene name synonym)|uniprotkb:Sacm2l-ps3(gene name synonym)|uniprotkb:Sacm2l-ps4(gene name synonym)|uniprotkb:Sacm2l-ps5(gene name synonym)|uniprotkb:Sacm2l-ps6(gene name synonym)|uniprotkb:Sacm2l-ps7(gene name synonym)|uniprotkb:Tnf(gene name synonym)|uniprotkb:rCG_38311(orf name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25746693|imex:IM-28175-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 ensembl:ENSRNOG00000000840(gene)|ensembl:ENSRNOT00000001114(transcript)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR005124("Vacuolar (H+)-ATPase G subunit")|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|rcsb pdb:6VQI|rcsb pdb:6VQJ|rcsb pdb:6VQK|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712|rgd:1303186|refseq:NP_997655.1 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rogid:Io9s6t7jqRyHwDR0fHjvHSKpkvM10116 rigid:FyI5aY3/KDjTYGK8vcF17qifI+0 false - - 3 3 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:D4A133 uniprotkb:P62815 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 intact:EBI-772667|uniprotkb:O09045|uniprotkb:P50517|ensembl:ENSRNOP00000015931 psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:vatb2_rat(display_long)|uniprotkb:Vacuolar proton pump subunit B 2(gene name synonym)|uniprotkb:Endomembrane proton pump 58 kDa subunit(gene name synonym)|uniprotkb:Atp6v1b2(gene name)|psi-mi:Atp6v1b2(display_short)|uniprotkb:Atp6b2(gene name synonym)|uniprotkb:Vat2(gene name synonym) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25746693|imex:IM-28175-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 rgd:620284|refseq:NP_476561.1|ensembl:ENSRNOG00000011891(gene)|ensembl:ENSRNOT00000015931(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0001726"(ruffle)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0042470"(melanosome)|go:"GO:0046034"(ATP metabolic process)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005723(ATPase, V1 complex, subunit B)|interpro:IPR020003|interpro:IPR022879|interpro:IPR027417|mint:P62815|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rogid:cmFm/xe3iOTqmy849cfoi4XeG+A10116 rigid:FyI5aY3/KDjTYGK8vcF17qifI+0 false - - 3 3 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:D4A133 uniprotkb:Q6PCU2 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 intact:EBI-919161 psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:vate1_rat(display_long)|uniprotkb:Atp6v1e1(gene name)|psi-mi:Atp6v1e1(display_short)|uniprotkb:Vacuolar proton pump subunit E 1(gene name synonym) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25746693|imex:IM-28175-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 rgd:735157|refseq:NP_942040.1|interpro:IPR002842(ATPase, V1/A1 complex, subunit E)|mint:Q6PCU2|interpro:IPR038495|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:1902600"(proton transmembrane transport)|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|rcsb pdb:6VQI|rcsb pdb:6VQJ|rcsb pdb:6VQK|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rogid:mfYO92S6Lf0DGuQmxSaUAoCmQcw10116 rigid:FyI5aY3/KDjTYGK8vcF17qifI+0 false - - 3 3 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:D4A133 uniprotkb:P50408 intact:EBI-2257711|ensembl:ENSRNOP00000002727|ensembl:ENSRNOP00000076121 intact:EBI-917679|ensembl:ENSRNOP00000009737 psi-mi:d4a133_rat(display_long)|uniprotkb:rCG_52629(orf name)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short) psi-mi:vatf_rat(display_long)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym)|uniprotkb:Atp6v1f(gene name)|psi-mi:Atp6v1f(display_short)|uniprotkb:Atp6s14(gene name synonym)|uniprotkb:Vatf(gene name synonym) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Abbas et al. (2020) pubmed:32165585|imex:IM-28175 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25746693|imex:IM-28175-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1596464|refseq:NP_001101788.1|refseq:XP_006248410.1|refseq:XP_006248411.1|ensembl:ENSRNOG00000001992(gene)|ensembl:ENSRNOT00000002727(transcript)|ensembl:ENSRNOT00000093467(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:D4A133|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712 ensembl:ENSRNOG00000007392(gene)|ensembl:ENSRNOT00000009737(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033180"(proton-transporting V-type ATPase, V1 domain)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rgd:621552|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712|refseq:NP_446336.1 wwpdb:6VQ9(subset)|wwpdb:6VQA(subset)|wwpdb:6VQB(subset)|wwpdb:6VQC(subset)|wwpdb:6VQG(subset)|wwpdb:6VQH(subset)|wwpdb:6VQI(subset)|wwpdb:6VQJ(subset)|wwpdb:6VQK(subset)|emdb:EMD-21347(subset)|emdb:EMD-21345(subset)|emdb:EMD-21346(subset)|emdb:EMD-21348(subset)|emdb:EMD-21349(subset)|emdb:EMD-21350(subset)|emdb:EMD-21351(subset)|emdb:EMD-21352(subset)|emdb:EMD-21353(subset) - - figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/07/01 2020/07/13 rogid:3t3xWxMz2G31Cg0nNzn750mOj4Q10116 rogid:3fcGzehnyb0ieULlCF2CLvnmUhc10116 rigid:FyI5aY3/KDjTYGK8vcF17qifI+0 false - - 3 1 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry)