#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q12285	uniprotkb:Q12285	intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C	intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C	psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name)	psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Simon et al. (2013)	pubmed:23297211|imex:IM-28359	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-26302650|wwpdb:4A20|imex:IM-28359-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK	refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK	-	crc64:CE6FC4282E0E472C	crc64:CE6FC4282E0E472C	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2020/09/17	2020/09/17	rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292	rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292	rigid:p95S+N5uZkDbF8FS2Q2uWnHS+yQ	false	binding-associated region:70-152(IPR000626)|his tag:n-n	binding-associated region:70-152(IPR000626)|his tag:n-n	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12118	uniprotkb:Q12118	intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C	intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C	psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)	psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)	psi-mi:"MI:1103"(solution state nmr)	Simon et al. (2013)	pubmed:23297211|imex:IM-28359	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-26302663|wwpdb:4ASV|imex:IM-28359-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523	refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523	-	crc64:33539B74F742BD3C	crc64:33539B74F742BD3C	figure legend:Fig 1, Table S1|comment:Experiments on mixed 13C/15N- and unlabeled Sgt2_NT dimers.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/17	2020/09/17	rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292	rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292	rigid:Ab6ImX1QHM8e04eb1/cY6/oIgqA	false	his tag:n-n|binding-associated region:1-78	his tag:n-n|binding-associated region:1-78	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12285	uniprotkb:Q12118	intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C	intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C	psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name)	psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)	psi-mi:"MI:1103"(solution state nmr)	Simon et al. (2013)	pubmed:23297211|imex:IM-28359	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-26302669|wwpdb:4ASW|imex:IM-28359-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK	refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523	-	crc64:CE6FC4282E0E472C	crc64:33539B74F742BD3C	figure legend:Figure S1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/17	2020/09/21	rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292	rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292	rigid:1Dk8Lg6VdaPv77e3vLq+FdCPd3Y	false	binding-associated region:70-152(IPR000626)	binding-associated region:1-78|15n label:?-?	1	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12118	uniprotkb:Q12118	intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C	intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C	psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)	psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)	psi-mi:"MI:1103"(solution state nmr)	Simon et al. (2013)	pubmed:23297211|imex:IM-28359	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-26355058|imex:IM-28359-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523	refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523	-	crc64:33539B74F742BD3C	crc64:33539B74F742BD3C	figure legend:Fig 1, Table S1|comment:Experiments on mixed 13C/15N- and unlabeled Sgt2_NT dimers.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/17	2020/09/21	rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292	rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292	rigid:mmtD4irrtiIV6dsz3UoDRum1HlU	false	his tag:n-n|binding-associated region:1-78|13c label:?-?|15n label:?-?	his tag:n-n|binding-associated region:1-78	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12118	uniprotkb:Q12118	intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C	intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C	psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)	psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)	psi-mi:"MI:1103"(solution state nmr)	Simon et al. (2013)	pubmed:23297211|imex:IM-28359	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-26355075|imex:IM-28359-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523	refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523	-	crc64:33539B74F742BD3C	crc64:33539B74F742BD3C	figure legend:Fig 1, Table S1|comment:Experiments on mixed 13C/15N- and unlabeled Sgt2_NT dimers.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/17	2020/09/21	rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292	rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292	rigid:mmtD4irrtiIV6dsz3UoDRum1HlU	false	his tag:n-n|binding-associated region:1-78|13c label:?-?|15n label:?-?	his tag:n-n|binding-associated region:1-78|13c label:?-?|15n label:?-?	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12285	uniprotkb:Q12118	intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C	intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C	psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name)	psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)	psi-mi:"MI:1103"(solution state nmr)	Simon et al. (2013)	pubmed:23297211|imex:IM-28359	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-26355105|imex:IM-28359-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK	refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523	-	crc64:CE6FC4282E0E472C	crc64:33539B74F742BD3C	figure legend:Figure S1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/17	2020/09/21	rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292	rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292	rigid:1Dk8Lg6VdaPv77e3vLq+FdCPd3Y	false	binding-associated region:70-152(IPR000626)|15n label:?-?	binding-associated region:1-78	1	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12285	uniprotkb:Q12118	intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C	intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C	psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name)	psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Simon et al. (2013)	pubmed:23297211|imex:IM-28359	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-26302723|imex:IM-28359-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK	refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523	-	crc64:CE6FC4282E0E472C	crc64:33539B74F742BD3C	figure legend:Fig 2, Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:0.11x10^-6(molar)	2020/09/17	2020/09/21	rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292	rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292	rigid:1Dk8Lg6VdaPv77e3vLq+FdCPd3Y	false	binding-associated region:70-152(IPR000626)	binding-associated region:1-78|mutation disrupting interaction strength:38-38|mutation with no effect:16-16|mutation decreasing interaction strength:31-31|mutation decreasing interaction strength:35-35|mutation decreasing interaction strength:42-42	1	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)