#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q6SZW1-1 uniprotkb:Q6SZW1-1 intact:EBI-22054385|ensembl:ENSP00000468032 intact:EBI-22054385|ensembl:ENSP00000468032 psi-mi:q6szw1-1(display_long)|uniprotkb:SARM1(gene name)|psi-mi:SARM1(display_short)|uniprotkb:KIAA0524(gene name synonym)|uniprotkb:SAMD2(gene name synonym)|uniprotkb:SARM(gene name synonym)|uniprotkb:"NADP(+) hydrolase SARM1"(gene name synonym)|uniprotkb:Sterile alpha and TIR motif-containing protein 1(gene name synonym)|uniprotkb:Sterile alpha and Armadillo repeat protein(gene name synonym)|uniprotkb:Sterile alpha motif domain-containing protein 2(gene name synonym)|uniprotkb:Tir-1 homolog(gene name synonym) psi-mi:q6szw1-1(display_long)|uniprotkb:SARM1(gene name)|psi-mi:SARM1(display_short)|uniprotkb:KIAA0524(gene name synonym)|uniprotkb:SAMD2(gene name synonym)|uniprotkb:SARM(gene name synonym)|uniprotkb:"NADP(+) hydrolase SARM1"(gene name synonym)|uniprotkb:Sterile alpha and TIR motif-containing protein 1(gene name synonym)|uniprotkb:Sterile alpha and Armadillo repeat protein(gene name synonym)|uniprotkb:Sterile alpha motif domain-containing protein 2(gene name synonym)|uniprotkb:Tir-1 homolog(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Horsefield et al. (2019) pubmed:31439792|imex:IM-27623 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-22054383|wwpdb:6O0S|wwpdb:6O0T|imex:IM-27623-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11693532(isoform-parent)|ensembl:ENSG00000004139(gene)|ensembl:ENST00000585482(transcript) intact:EBI-11693532(isoform-parent)|ensembl:ENSG00000004139(gene)|ensembl:ENST00000585482(transcript) - - - figure legend:Fig 1B. Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2019/09/28 2019/11/14 rogid:n7sfGqChRoQGfwzfXUJV8AY3jDY9606 rogid:n7sfGqChRoQGfwzfXUJV8AY3jDY9606 rigid:ZXLqEuabwSdbSlvPMToQhVr4iKI false his tag:n-n|binding-associated region:409-561(IPR001660)|mutation:473-473|mutation with no effect:446-446,505-505,523-523 his tag:n-n|binding-associated region:409-561(IPR001660)|mutation:473-473|mutation with no effect:446-446,505-505,523-523 8 0 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:Q6SZW1-1 uniprotkb:Q6SZW1-1 intact:EBI-22054385|ensembl:ENSP00000468032 intact:EBI-22054385|ensembl:ENSP00000468032 psi-mi:q6szw1-1(display_long)|uniprotkb:SARM1(gene name)|psi-mi:SARM1(display_short)|uniprotkb:KIAA0524(gene name synonym)|uniprotkb:SAMD2(gene name synonym)|uniprotkb:SARM(gene name synonym)|uniprotkb:"NADP(+) hydrolase SARM1"(gene name synonym)|uniprotkb:Sterile alpha and TIR motif-containing protein 1(gene name synonym)|uniprotkb:Sterile alpha and Armadillo repeat protein(gene name synonym)|uniprotkb:Sterile alpha motif domain-containing protein 2(gene name synonym)|uniprotkb:Tir-1 homolog(gene name synonym) psi-mi:q6szw1-1(display_long)|uniprotkb:SARM1(gene name)|psi-mi:SARM1(display_short)|uniprotkb:KIAA0524(gene name synonym)|uniprotkb:SAMD2(gene name synonym)|uniprotkb:SARM(gene name synonym)|uniprotkb:"NADP(+) hydrolase SARM1"(gene name synonym)|uniprotkb:Sterile alpha and TIR motif-containing protein 1(gene name synonym)|uniprotkb:Sterile alpha and Armadillo repeat protein(gene name synonym)|uniprotkb:Sterile alpha motif domain-containing protein 2(gene name synonym)|uniprotkb:Tir-1 homolog(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Horsefield et al. (2019) pubmed:31439792|imex:IM-27623 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-22054466|imex:IM-27623-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11693532(isoform-parent)|ensembl:ENSG00000004139(gene)|ensembl:ENST00000585482(transcript) intact:EBI-11693532(isoform-parent)|ensembl:ENSG00000004139(gene)|ensembl:ENST00000585482(transcript) - - - figure legend:Fig 3A, S11|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2019/09/28 2020/01/08 rogid:n7sfGqChRoQGfwzfXUJV8AY3jDY9606 rogid:n7sfGqChRoQGfwzfXUJV8AY3jDY9606 rigid:ZXLqEuabwSdbSlvPMToQhVr4iKI false mutation disrupting interaction strength:442-442,461-461,514-514,531-531,533-533|binding-associated region:409-561|mutation:473-473|his tag:n-n mutation disrupting interaction strength:442-442,461-461,514-514,531-531,533-533|binding-associated region:409-561|mutation:473-473|his tag:n-n 8 0 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:Q6PDS3-1 uniprotkb:Q6PDS3-1 intact:EBI-22055238|ensembl:ENSMUSP00000051059 intact:EBI-22055238|ensembl:ENSMUSP00000051059 psi-mi:q6pds3-1(display_long)|uniprotkb:"NADP(+) hydrolase SARM1"(gene name synonym)|uniprotkb:Sterile alpha and TIR motif-containing protein 1(gene name synonym)|uniprotkb:Sarm1(gene name)|psi-mi:Sarm1(display_short)|uniprotkb:Kiaa0524(gene name synonym) psi-mi:q6pds3-1(display_long)|uniprotkb:"NADP(+) hydrolase SARM1"(gene name synonym)|uniprotkb:Sterile alpha and TIR motif-containing protein 1(gene name synonym)|uniprotkb:Sarm1(gene name)|psi-mi:Sarm1(display_short)|uniprotkb:Kiaa0524(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Horsefield et al. (2019) pubmed:31439792|imex:IM-27623 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-22055236|imex:IM-27623-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6117196(isoform-parent)|ensembl:ENSMUSG00000050132(gene)|ensembl:ENSMUST00000061174(transcript) intact:EBI-6117196(isoform-parent)|ensembl:ENSMUSG00000050132(gene)|ensembl:ENSMUST00000061174(transcript) go:"GO:0051260"(protein homooligomerization) - - figure legend:Fig S16C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2019/09/28 2019/12/16 rogid:tIi/ujPHqfCjECm37VY+KKMx0Xk10090 rogid:tIi/ujPHqfCjECm37VY+KKMx0Xk10090 rigid:w159UUBQ4WiQjNTp1tdvQ6hWBHY false mutation disrupting interaction:442-442,461-461,514-514,531-531,533-533 mutation disrupting interaction:442-442,461-461,514-514,531-531,533-533 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6SZW1-1 uniprotkb:Q6SZW1-1 intact:EBI-22054385|ensembl:ENSP00000468032 intact:EBI-22054385|ensembl:ENSP00000468032 psi-mi:q6szw1-1(display_long)|uniprotkb:SARM1(gene name)|psi-mi:SARM1(display_short)|uniprotkb:KIAA0524(gene name synonym)|uniprotkb:SAMD2(gene name synonym)|uniprotkb:SARM(gene name synonym)|uniprotkb:"NADP(+) hydrolase SARM1"(gene name synonym)|uniprotkb:Sterile alpha and TIR motif-containing protein 1(gene name synonym)|uniprotkb:Sterile alpha and Armadillo repeat protein(gene name synonym)|uniprotkb:Sterile alpha motif domain-containing protein 2(gene name synonym)|uniprotkb:Tir-1 homolog(gene name synonym) psi-mi:q6szw1-1(display_long)|uniprotkb:SARM1(gene name)|psi-mi:SARM1(display_short)|uniprotkb:KIAA0524(gene name synonym)|uniprotkb:SAMD2(gene name synonym)|uniprotkb:SARM(gene name synonym)|uniprotkb:"NADP(+) hydrolase SARM1"(gene name synonym)|uniprotkb:Sterile alpha and TIR motif-containing protein 1(gene name synonym)|uniprotkb:Sterile alpha and Armadillo repeat protein(gene name synonym)|uniprotkb:Sterile alpha motif domain-containing protein 2(gene name synonym)|uniprotkb:Tir-1 homolog(gene name synonym) psi-mi:"MI:0826"(x ray scattering) Horsefield et al. (2019) pubmed:31439792|imex:IM-27623 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-22054434|imex:IM-27623-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11693532(isoform-parent)|ensembl:ENSG00000004139(gene)|ensembl:ENST00000585482(transcript) intact:EBI-11693532(isoform-parent)|ensembl:ENSG00000004139(gene)|ensembl:ENST00000585482(transcript) - - - figure legend:Fig S11|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2019/09/28 2019/11/14 rogid:n7sfGqChRoQGfwzfXUJV8AY3jDY9606 rogid:n7sfGqChRoQGfwzfXUJV8AY3jDY9606 rigid:ZXLqEuabwSdbSlvPMToQhVr4iKI false binding-associated region:409-561|mutation:473-473 binding-associated region:409-561|mutation:473-473 8 0 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)