#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q7ZWK8	uniprotkb:Q7ZWK8	intact:EBI-22085919|uniprotkb:B2GQA4|uniprotkb:Q5MKL8|uniprotkb:Q5XJ61	intact:EBI-22085919|uniprotkb:B2GQA4|uniprotkb:Q5MKL8|uniprotkb:Q5XJ61	psi-mi:otop1_danre(display_long)|uniprotkb:Otopetrin-1(gene name synonym)|uniprotkb:otop1(gene name)|psi-mi:otop1(display_short)	psi-mi:otop1_danre(display_long)|uniprotkb:Otopetrin-1(gene name synonym)|uniprotkb:otop1(gene name)|psi-mi:otop1(display_short)	psi-mi:"MI:0410"(3D electron microscopy)	Saotome et al. (2019)	imex:IM-27488|pubmed:31160780	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-22085917|wwpdb:6NF4|emdb:EMD-9360|imex:IM-27488-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_942098.1|interpro:IPR004878(Protein of unknown function DUF270)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015252"(proton channel activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032475"(otolith formation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045299"(otolith mineralization)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:1902600"(proton transmembrane transport)	refseq:NP_942098.1|interpro:IPR004878(Protein of unknown function DUF270)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015252"(proton channel activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032475"(otolith formation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045299"(otolith mineralization)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:1902600"(proton transmembrane transport)	-	-	-	figure legend:Fig 1b, Tab.1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2019/10/14	2019/10/14	rogid:EtGO+SkVYtXi/RNU4pu0NghUY7k7955	rogid:EtGO+SkVYtXi/RNU4pu0NghUY7k7955	rigid:cOBBt7U8KamDlEHq4xfV401GSgA	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:R4GK65	uniprotkb:R4GK65	intact:EBI-22085938|ensembl:ENSGALP00000042554	intact:EBI-22085938|ensembl:ENSGALP00000042554	psi-mi:r4gk65_chick(display_long)|uniprotkb:OTOP3(gene name)|psi-mi:OTOP3(display_short)	psi-mi:r4gk65_chick(display_long)|uniprotkb:OTOP3(gene name)|psi-mi:OTOP3(display_short)	psi-mi:"MI:0410"(3D electron microscopy)	Saotome et al. (2019)	imex:IM-27488|pubmed:31160780	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-22085964|wwpdb:6NF6|emdb:EMD-9361|imex:IM-27488-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_015150946.1|refseq:XP_015150947.1|refseq:XP_420115.3|ensembl:ENSGALG00000028214(gene)|ensembl:ENSGALT00000042989(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR004878(Protein of unknown function DUF270)	refseq:XP_015150946.1|refseq:XP_015150947.1|refseq:XP_420115.3|ensembl:ENSGALG00000028214(gene)|ensembl:ENSGALT00000042989(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR004878(Protein of unknown function DUF270)	-	-	-	figure legend:Fig 1c, Tab 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2019/10/14	2019/10/14	rogid:ZB95kdEwF0J7e/WKerY1A1nhrMU9031	rogid:ZB95kdEwF0J7e/WKerY1A1nhrMU9031	rigid:zg+f9/jMiVKk2C+/jemayS+bMQ8	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q7ZWK8	uniprotkb:Q7ZWK8	intact:EBI-22085919|uniprotkb:B2GQA4|uniprotkb:Q5MKL8|uniprotkb:Q5XJ61	intact:EBI-22085919|uniprotkb:B2GQA4|uniprotkb:Q5MKL8|uniprotkb:Q5XJ61	psi-mi:otop1_danre(display_long)|uniprotkb:Otopetrin-1(gene name synonym)|uniprotkb:otop1(gene name)|psi-mi:otop1(display_short)	psi-mi:otop1_danre(display_long)|uniprotkb:Otopetrin-1(gene name synonym)|uniprotkb:otop1(gene name)|psi-mi:otop1(display_short)	psi-mi:"MI:0071"(molecular sieving)	Saotome et al. (2019)	imex:IM-27488|pubmed:31160780	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-22085969|wwpdb:6NF4|imex:IM-27488-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_942098.1|interpro:IPR004878(Protein of unknown function DUF270)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015252"(proton channel activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032475"(otolith formation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045299"(otolith mineralization)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:1902600"(proton transmembrane transport)	refseq:NP_942098.1|interpro:IPR004878(Protein of unknown function DUF270)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015252"(proton channel activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032475"(otolith formation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045299"(otolith mineralization)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:1902600"(proton transmembrane transport)	-	-	-	figure legend:Supp. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2019/10/14	2019/10/14	rogid:EtGO+SkVYtXi/RNU4pu0NghUY7k7955	rogid:EtGO+SkVYtXi/RNU4pu0NghUY7k7955	rigid:cOBBt7U8KamDlEHq4xfV401GSgA	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:R4GK65	uniprotkb:R4GK65	intact:EBI-22085938|ensembl:ENSGALP00000042554	intact:EBI-22085938|ensembl:ENSGALP00000042554	psi-mi:r4gk65_chick(display_long)|uniprotkb:OTOP3(gene name)|psi-mi:OTOP3(display_short)	psi-mi:r4gk65_chick(display_long)|uniprotkb:OTOP3(gene name)|psi-mi:OTOP3(display_short)	psi-mi:"MI:0071"(molecular sieving)	Saotome et al. (2019)	imex:IM-27488|pubmed:31160780	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-22085973|imex:IM-27488-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_015150946.1|refseq:XP_015150947.1|refseq:XP_420115.3|ensembl:ENSGALG00000028214(gene)|ensembl:ENSGALT00000042989(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR004878(Protein of unknown function DUF270)	refseq:XP_015150946.1|refseq:XP_015150947.1|refseq:XP_420115.3|ensembl:ENSGALG00000028214(gene)|ensembl:ENSGALT00000042989(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR004878(Protein of unknown function DUF270)	-	-	-	figure legend:Supp. Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2019/10/14	2019/10/14	rogid:ZB95kdEwF0J7e/WKerY1A1nhrMU9031	rogid:ZB95kdEwF0J7e/WKerY1A1nhrMU9031	rigid:zg+f9/jMiVKk2C+/jemayS+bMQ8	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)