#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:C4QZ45	uniprotkb:C4QZQ7	intact:EBI-21272934|ensemblfungi:CAY68519	intact:EBI-20800027|ensemblfungi:CAY68731	psi-mi:c4qz45_kompg(display_long)|uniprotkb:PAS_c121_0006(locus name)	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21272990|wwpdb:6IR9|emdb:EMD-9713|wwpdb:6J4X|emdb:EMD-0672|wwpdb:6J4Y|emdb:EMD-0673|wwpdb:6J4W|emdb:EMD-0671|wwpdb:6J51|emdb:EMD-0676|imex:IM-27000-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J51|ensemblfungi:CAY68519(transcript)|ensemblfungi:PAS_c121_0006(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|refseq:XP_002490799.1|interpro:IPR007808(Protein of unknown function DUF701, zinc-binding putative)|interpro:IPR038567	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. 1 and S5 and S6, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:RkWbUdsBYdChoYY7PNim4W09k0w644223	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rigid:bu2fRSb5w1xmr1TmgmuuE/ZxEX0	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZ45	uniprotkb:C4R009	intact:EBI-21272934|ensemblfungi:CAY68519	intact:EBI-20800218|ensemblfungi:CAY68833	psi-mi:c4qz45_kompg(display_long)|uniprotkb:PAS_c121_0006(locus name)	psi-mi:c4r009_kompg(display_long)|uniprotkb:PAS_chr2-1_0223(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21272990|wwpdb:6IR9|emdb:EMD-9713|wwpdb:6J4X|emdb:EMD-0672|wwpdb:6J4Y|emdb:EMD-0673|wwpdb:6J4W|emdb:EMD-0671|wwpdb:6J51|emdb:EMD-0676|imex:IM-27000-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J51|ensemblfungi:CAY68519(transcript)|ensemblfungi:PAS_c121_0006(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|refseq:XP_002490799.1|interpro:IPR007808(Protein of unknown function DUF701, zinc-binding putative)|interpro:IPR038567	rcsb pdb:6IR9|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY68833(transcript)|ensemblfungi:PAS_chr2-1_0223(gene)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0001056"(RNA polymerase III activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:6INQ|refseq:XP_002491113.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR023580|interpro:IPR020789|interpro:IPR000268(RNA polymerases, N/8 Kd subunits)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. 1 and S5 and S6, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:RkWbUdsBYdChoYY7PNim4W09k0w644223	rogid:1ay4K0OWVYfU09LaWaEKYqDEXuk644223	rigid:bu2fRSb5w1xmr1TmgmuuE/ZxEX0	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZ45	uniprotkb:C4R0E6	intact:EBI-21272934|ensemblfungi:CAY68519	intact:EBI-21272943|ensemblfungi:CAY68970	psi-mi:c4qz45_kompg(display_long)|uniprotkb:PAS_c121_0006(locus name)	psi-mi:c4r0e6_kompg(display_long)|uniprotkb:PAS_chr2-1_0350(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21272990|wwpdb:6IR9|emdb:EMD-9713|wwpdb:6J4X|emdb:EMD-0672|wwpdb:6J4Y|emdb:EMD-0673|wwpdb:6J4W|emdb:EMD-0671|wwpdb:6J51|emdb:EMD-0676|imex:IM-27000-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J51|ensemblfungi:CAY68519(transcript)|ensemblfungi:PAS_c121_0006(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|refseq:XP_002490799.1|interpro:IPR007808(Protein of unknown function DUF701, zinc-binding putative)|interpro:IPR038567	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:PAS_chr2-1_0350(gene)|go:"GO:0000182"(rDNA binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0006342"|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|ensemblfungi:CAY68970(transcript)|refseq:XP_002491250.1|rcsb pdb:5XON|interpro:IPR029040|interpro:IPR009287(Transcription initiation Spt4)|interpro:IPR022800|interpro:IPR038510	-	-	-	figure legend:Figs. 1 and S5 and S6, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:RkWbUdsBYdChoYY7PNim4W09k0w644223	rogid:ywCrJ9W9Xggw4QlYjFSer87BELk644223	rigid:bu2fRSb5w1xmr1TmgmuuE/ZxEX0	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZ45	uniprotkb:C4R1V1	intact:EBI-21272934|ensemblfungi:CAY68519	intact:EBI-20800134|ensemblfungi:CAY69475	psi-mi:c4qz45_kompg(display_long)|uniprotkb:PAS_c121_0006(locus name)	psi-mi:c4r1v1_kompg(display_long)|uniprotkb:PAS_chr2-2_0434(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21272990|wwpdb:6IR9|emdb:EMD-9713|wwpdb:6J4X|emdb:EMD-0672|wwpdb:6J4Y|emdb:EMD-0673|wwpdb:6J4W|emdb:EMD-0671|wwpdb:6J51|emdb:EMD-0676|imex:IM-27000-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J51|ensemblfungi:CAY68519(transcript)|ensemblfungi:PAS_c121_0006(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|refseq:XP_002490799.1|interpro:IPR007808(Protein of unknown function DUF701, zinc-binding putative)|interpro:IPR038567	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY69475(transcript)|ensemblfungi:PAS_chr2-2_0434(gene)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0001056"(RNA polymerase III activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:6INQ|refseq:XP_002491755.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR020708|interpro:IPR006110(RNA polymerase Rpb6)|interpro:IPR012293(RNA polymerase subunit, RPB6/omega)|interpro:IPR028363|interpro:IPR036161|interpro:IPR006111(DNA-directed RNA polymerase, 14 to 18 kDa subunit)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. 1 and S5 and S6, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:RkWbUdsBYdChoYY7PNim4W09k0w644223	rogid:sOgXLbXs4iRGdaUFfb88ZVm1W98644223	rigid:bu2fRSb5w1xmr1TmgmuuE/ZxEX0	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZ45	uniprotkb:C4R273	intact:EBI-21272934|ensemblfungi:CAY68519	intact:EBI-20800178|ensemblfungi:CAY69597	psi-mi:c4qz45_kompg(display_long)|uniprotkb:PAS_c121_0006(locus name)	psi-mi:c4r273_kompg(display_long)|uniprotkb:PAS_chr2-2_0309(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21272990|wwpdb:6IR9|emdb:EMD-9713|wwpdb:6J4X|emdb:EMD-0672|wwpdb:6J4Y|emdb:EMD-0673|wwpdb:6J4W|emdb:EMD-0671|wwpdb:6J51|emdb:EMD-0676|imex:IM-27000-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J51|ensemblfungi:CAY68519(transcript)|ensemblfungi:PAS_c121_0006(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|refseq:XP_002490799.1|interpro:IPR007808(Protein of unknown function DUF701, zinc-binding putative)|interpro:IPR038567	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY69597(transcript)|ensemblfungi:PAS_chr2-2_0309(gene)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0001056"(RNA polymerase III activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:6INQ|refseq:XP_002491877.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR005570(RNA polymerase, Rpb8)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. 1 and S5 and S6, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:RkWbUdsBYdChoYY7PNim4W09k0w644223	rogid:MnvasHhqga4MIKsh8kH1/bpM0wc644223	rigid:bu2fRSb5w1xmr1TmgmuuE/ZxEX0	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZ45	uniprotkb:C4R2U9	intact:EBI-21272934|ensemblfungi:CAY68519	intact:EBI-20800081|ensemblfungi:CAY69823	psi-mi:c4qz45_kompg(display_long)|uniprotkb:PAS_c121_0006(locus name)	psi-mi:c4r2u9_kompg(display_long)|uniprotkb:PAS_chr2-2_0104(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21272990|wwpdb:6IR9|emdb:EMD-9713|wwpdb:6J4X|emdb:EMD-0672|wwpdb:6J4Y|emdb:EMD-0673|wwpdb:6J4W|emdb:EMD-0671|wwpdb:6J51|emdb:EMD-0676|imex:IM-27000-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J51|ensemblfungi:CAY68519(transcript)|ensemblfungi:PAS_c121_0006(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|refseq:XP_002490799.1|interpro:IPR007808(Protein of unknown function DUF701, zinc-binding putative)|interpro:IPR038567	rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|ensemblfungi:CAY69823(transcript)|ensemblfungi:PAS_chr2-2_0104(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|rcsb pdb:6INQ|refseq:XP_002492103.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR010997(HRDC-like)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR038324|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. 1 and S5 and S6, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:RkWbUdsBYdChoYY7PNim4W09k0w644223	rogid:/017Xpkf83C3N7U8UYAXzDWDlv8644223	rigid:bu2fRSb5w1xmr1TmgmuuE/ZxEX0	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZ45	uniprotkb:C4R370	intact:EBI-21272934|ensemblfungi:CAY68519	intact:EBI-21272973|ensemblfungi:CAY71204	psi-mi:c4qz45_kompg(display_long)|uniprotkb:PAS_c121_0006(locus name)	psi-mi:c4r370_kompg(display_long)|uniprotkb:Chromatin elongation factor spt5(gene name synonym)|uniprotkb:transcription Elongation factor SPT5(gene name synonym)|uniprotkb:PAS_chr3_1136(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21272990|wwpdb:6IR9|emdb:EMD-9713|wwpdb:6J4X|emdb:EMD-0672|wwpdb:6J4Y|emdb:EMD-0673|wwpdb:6J4W|emdb:EMD-0671|wwpdb:6J51|emdb:EMD-0676|imex:IM-27000-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J51|ensemblfungi:CAY68519(transcript)|ensemblfungi:PAS_c121_0006(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|refseq:XP_002490799.1|interpro:IPR007808(Protein of unknown function DUF701, zinc-binding putative)|interpro:IPR038567	interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY71204(transcript)|ensemblfungi:PAS_chr3_1136(gene)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|refseq:XP_002493383.1|rcsb pdb:5XON|interpro:IPR005824(KOW)|interpro:IPR005100(Supt5 repeat)|interpro:IPR036735|interpro:IPR039385|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR039659|interpro:IPR022581|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR008991(Translation protein SH3-like)	-	-	-	figure legend:Figs. 1 and S5 and S6, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:RkWbUdsBYdChoYY7PNim4W09k0w644223	rogid:fiReSF3elv/T+GigQdEyO6vkdHQ644223	rigid:bu2fRSb5w1xmr1TmgmuuE/ZxEX0	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZ45	uniprotkb:C4R3P8	intact:EBI-21272934|ensemblfungi:CAY68519	intact:EBI-20800108|ensemblfungi:CAY70112	psi-mi:c4qz45_kompg(display_long)|uniprotkb:PAS_c121_0006(locus name)	psi-mi:c4r3p8_kompg(display_long)|uniprotkb:PAS_chr3_0157(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21272990|wwpdb:6IR9|emdb:EMD-9713|wwpdb:6J4X|emdb:EMD-0672|wwpdb:6J4Y|emdb:EMD-0673|wwpdb:6J4W|emdb:EMD-0671|wwpdb:6J51|emdb:EMD-0676|imex:IM-27000-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J51|ensemblfungi:CAY68519(transcript)|ensemblfungi:PAS_c121_0006(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|refseq:XP_002490799.1|interpro:IPR007808(Protein of unknown function DUF701, zinc-binding putative)|interpro:IPR038567	rcsb pdb:6J50|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J51|ensemblfungi:CAY70112(transcript)|ensemblfungi:PAS_chr3_0157(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|rcsb pdb:6INQ|refseq:XP_002492363.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR036710|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR020608|interpro:IPR035913|interpro:IPR020609|interpro:IPR039531|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. 1 and S5 and S6, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:RkWbUdsBYdChoYY7PNim4W09k0w644223	rogid:uvHyo3JNliA/f1LdlRdTrLHAhu8644223	rigid:bu2fRSb5w1xmr1TmgmuuE/ZxEX0	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZ45	uniprotkb:C4R3Z5	intact:EBI-21272934|ensemblfungi:CAY68519	intact:EBI-20800241|ensemblfungi:CAY70274	psi-mi:c4qz45_kompg(display_long)|uniprotkb:PAS_c121_0006(locus name)	psi-mi:c4r3z5_kompg(display_long)|uniprotkb:PAS_chr3_0244(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21272990|wwpdb:6IR9|emdb:EMD-9713|wwpdb:6J4X|emdb:EMD-0672|wwpdb:6J4Y|emdb:EMD-0673|wwpdb:6J4W|emdb:EMD-0671|wwpdb:6J51|emdb:EMD-0676|imex:IM-27000-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J51|ensemblfungi:CAY68519(transcript)|ensemblfungi:PAS_c121_0006(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|refseq:XP_002490799.1|interpro:IPR007808(Protein of unknown function DUF701, zinc-binding putative)|interpro:IPR038567	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY70274(transcript)|ensemblfungi:PAS_chr3_0244(gene)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0046983"(protein dimerization activity)|rcsb pdb:6INQ|refseq:XP_002492460.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR037685|interpro:IPR036603|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. 1 and S5 and S6, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:RkWbUdsBYdChoYY7PNim4W09k0w644223	rogid:Bcxi1i7CjZerdkNw1zlStjnDbGA644223	rigid:bu2fRSb5w1xmr1TmgmuuE/ZxEX0	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZ45	uniprotkb:C4R4Y0	intact:EBI-21272934|ensemblfungi:CAY68519	intact:EBI-20799999|ensemblfungi:CAY70616	psi-mi:c4qz45_kompg(display_long)|uniprotkb:PAS_c121_0006(locus name)	psi-mi:c4r4y0_kompg(display_long)|uniprotkb:PAS_chr3_0568(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21272990|wwpdb:6IR9|emdb:EMD-9713|wwpdb:6J4X|emdb:EMD-0672|wwpdb:6J4Y|emdb:EMD-0673|wwpdb:6J4W|emdb:EMD-0671|wwpdb:6J51|emdb:EMD-0676|imex:IM-27000-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J51|ensemblfungi:CAY68519(transcript)|ensemblfungi:PAS_c121_0006(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|refseq:XP_002490799.1|interpro:IPR007808(Protein of unknown function DUF701, zinc-binding putative)|interpro:IPR038567	interpro:IPR042102|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY70616(transcript)|ensemblfungi:PAS_chr3_0568(gene)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002492795.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR038593|interpro:IPR038120|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. 1 and S5 and S6, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:RkWbUdsBYdChoYY7PNim4W09k0w644223	rogid:/Iegq8f+rYdUcNLjKKqdngz4RxI644223	rigid:bu2fRSb5w1xmr1TmgmuuE/ZxEX0	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZ45	uniprotkb:C4R7L2	intact:EBI-21272934|ensemblfungi:CAY68519	intact:EBI-20800059|ensemblfungi:CAY71587	psi-mi:c4qz45_kompg(display_long)|uniprotkb:PAS_c121_0006(locus name)	psi-mi:c4r7l2_kompg(display_long)|uniprotkb:PAS_chr4_0344(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21272990|wwpdb:6IR9|emdb:EMD-9713|wwpdb:6J4X|emdb:EMD-0672|wwpdb:6J4Y|emdb:EMD-0673|wwpdb:6J4W|emdb:EMD-0671|wwpdb:6J51|emdb:EMD-0676|imex:IM-27000-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J51|ensemblfungi:CAY68519(transcript)|ensemblfungi:PAS_c121_0006(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|refseq:XP_002490799.1|interpro:IPR007808(Protein of unknown function DUF701, zinc-binding putative)|interpro:IPR038567	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY71587(transcript)|ensemblfungi:PAS_chr4_0344(gene)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|rcsb pdb:6INQ|refseq:XP_002493766.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. 1 and S5 and S6, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:RkWbUdsBYdChoYY7PNim4W09k0w644223	rogid:aRUBPn6vT0brJH8ce/7n4CfRPV8644223	rigid:bu2fRSb5w1xmr1TmgmuuE/ZxEX0	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZ45	uniprotkb:C4R9A1	intact:EBI-21272934|ensemblfungi:CAY68519	intact:EBI-20800159|ensemblfungi:CAY72176	psi-mi:c4qz45_kompg(display_long)|uniprotkb:PAS_c121_0006(locus name)	psi-mi:c4r9a1_kompg(display_long)|uniprotkb:PAS_chr4_0906(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21272990|wwpdb:6IR9|emdb:EMD-9713|wwpdb:6J4X|emdb:EMD-0672|wwpdb:6J4Y|emdb:EMD-0673|wwpdb:6J4W|emdb:EMD-0671|wwpdb:6J51|emdb:EMD-0676|imex:IM-27000-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J51|ensemblfungi:CAY68519(transcript)|ensemblfungi:PAS_c121_0006(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|refseq:XP_002490799.1|interpro:IPR007808(Protein of unknown function DUF701, zinc-binding putative)|interpro:IPR038567	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY72176(transcript)|ensemblfungi:PAS_chr4_0906(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0010590"(regulation of septum digestion after cytokinesis)|go:"GO:0097394"(telomeric repeat-containing RNA transcription by RNA polymerase II)|rcsb pdb:6INQ|refseq:XP_002494355.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036898|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR003029(S1, RNA binding)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. 1 and S5 and S6, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:RkWbUdsBYdChoYY7PNim4W09k0w644223	rogid:uE/3Z3mElfHD6zyWFofgkpflFOg644223	rigid:bu2fRSb5w1xmr1TmgmuuE/ZxEX0	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZ45	uniprotkb:F2QMI1	intact:EBI-21272934|ensemblfungi:CAY68519	intact:EBI-20800261|ensemblfungi:CCA36628	psi-mi:c4qz45_kompg(display_long)|uniprotkb:PAS_c121_0006(locus name)	psi-mi:f2qmi1_kompc(display_long)|uniprotkb:RPC10(gene name)|psi-mi:RPC10(display_short)|uniprotkb:PP7435_Chr1-0476(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:981350(kompc)|taxid:981350("Komagataella phaffii (strain ATCC 76273 / CBS 7435 / CECT 11047 / NRRL Y-11430 / Wegner 21-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21272990|wwpdb:6IR9|emdb:EMD-9713|wwpdb:6J4X|emdb:EMD-0672|wwpdb:6J4Y|emdb:EMD-0673|wwpdb:6J4W|emdb:EMD-0671|wwpdb:6J51|emdb:EMD-0676|imex:IM-27000-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J51|ensemblfungi:CAY68519(transcript)|ensemblfungi:PAS_c121_0006(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|refseq:XP_002490799.1|interpro:IPR007808(Protein of unknown function DUF701, zinc-binding putative)|interpro:IPR038567	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CCA36628(transcript)|ensemblfungi:PP7435_CHR1-0476(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|rcsb pdb:6INQ|rcsb pdb:5XOG|interpro:IPR006591(RNA polymerase Rbp10)|interpro:IPR029040|interpro:IPR039747|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. 1 and S5 and S6, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:RkWbUdsBYdChoYY7PNim4W09k0w644223	rogid:XNaJRCB6Mz0dez4DoFiRGfxeoZA981350	rigid:bu2fRSb5w1xmr1TmgmuuE/ZxEX0	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZ45	uniprotkb:F2QPE6	intact:EBI-21272934|ensemblfungi:CAY68519	intact:EBI-20800198|ensemblfungi:CCA37274	psi-mi:c4qz45_kompg(display_long)|uniprotkb:PAS_c121_0006(locus name)	psi-mi:f2qpe6_kompc(display_long)|uniprotkb:RPB9(gene name)|psi-mi:RPB9(display_short)|uniprotkb:PP7435_Chr1-1144(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:981350(kompc)|taxid:981350("Komagataella phaffii (strain ATCC 76273 / CBS 7435 / CECT 11047 / NRRL Y-11430 / Wegner 21-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21272990|wwpdb:6IR9|emdb:EMD-9713|wwpdb:6J4X|emdb:EMD-0672|wwpdb:6J4Y|emdb:EMD-0673|wwpdb:6J4W|emdb:EMD-0671|wwpdb:6J51|emdb:EMD-0676|imex:IM-27000-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J51|ensemblfungi:CAY68519(transcript)|ensemblfungi:PAS_c121_0006(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|refseq:XP_002490799.1|interpro:IPR007808(Protein of unknown function DUF701, zinc-binding putative)|interpro:IPR038567	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CCA37274(transcript)|ensemblfungi:PP7435_CHR1-1144(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|rcsb pdb:6INQ|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|interpro:IPR019761|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR034012|interpro:IPR001222(Zinc finger, TFIIS-type)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. 1 and S5 and S6, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:RkWbUdsBYdChoYY7PNim4W09k0w644223	rogid:K8GCq9GcWsMRVlapEcuaLTOLJfc981350	rigid:bu2fRSb5w1xmr1TmgmuuE/ZxEX0	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZ45	uniprotkb:P04908	intact:EBI-21272934|ensemblfungi:CAY68519	intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842	psi-mi:c4qz45_kompg(display_long)|uniprotkb:PAS_c121_0006(locus name)	psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21272990|wwpdb:6IR9|emdb:EMD-9713|wwpdb:6J4X|emdb:EMD-0672|wwpdb:6J4Y|emdb:EMD-0673|wwpdb:6J4W|emdb:EMD-0671|wwpdb:6J51|emdb:EMD-0676|imex:IM-27000-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J51|ensemblfungi:CAY68519(transcript)|ensemblfungi:PAS_c121_0006(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|refseq:XP_002490799.1|interpro:IPR007808(Protein of unknown function DUF701, zinc-binding putative)|interpro:IPR038567	refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N	-	-	-	figure legend:Figs. 1 and S5 and S6, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:RkWbUdsBYdChoYY7PNim4W09k0w644223	rogid:4Qno1mMYZB6FdNoojrzulWLVq849606	rigid:bu2fRSb5w1xmr1TmgmuuE/ZxEX0	false	-	-	1	2	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZ45	uniprotkb:P06899	intact:EBI-21272934|ensemblfungi:CAY68519	intact:EBI-6150252|uniprotkb:B2R4J4|uniprotkb:O60816|ensembl:ENSP00000342886|ensembl:ENSP00000476136	psi-mi:c4qz45_kompg(display_long)|uniprotkb:PAS_c121_0006(locus name)	psi-mi:h2b1j_human(display_long)|uniprotkb:H2BC11(gene name)|psi-mi:H2BC11(display_short)|uniprotkb:H2BFR(gene name synonym)|uniprotkb:HIST1H2BJ(gene name synonym)|uniprotkb:Histone H2B.1(gene name synonym)|uniprotkb:Histone H2B.r(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21272990|wwpdb:6IR9|emdb:EMD-9713|wwpdb:6J4X|emdb:EMD-0672|wwpdb:6J4Y|emdb:EMD-0673|wwpdb:6J4W|emdb:EMD-0671|wwpdb:6J51|emdb:EMD-0676|imex:IM-27000-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J51|ensemblfungi:CAY68519(transcript)|ensemblfungi:PAS_c121_0006(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|refseq:XP_002490799.1|interpro:IPR007808(Protein of unknown function DUF701, zinc-binding putative)|interpro:IPR038567	refseq:NP_066402.2|dip:DIP-421N|ensembl:ENSG00000124635(gene)|ensembl:ENST00000339812(transcript)|ensembl:ENST00000607124(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P06899|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WAA|rcsb pdb:3WTP|rcsb pdb:4CAY|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5FUG|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5VEY|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6YOV|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7K5X|rcsb pdb:3WA9|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225	-	-	-	figure legend:Figs. 1 and S5 and S6, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:RkWbUdsBYdChoYY7PNim4W09k0w644223	rogid:74GQlSjGG1Ez6Uog74VXPLryKBc9606	rigid:bu2fRSb5w1xmr1TmgmuuE/ZxEX0	false	-	-	1	2	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZ45	uniprotkb:P84243	intact:EBI-21272934|ensemblfungi:CAY68519	intact:EBI-120658|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q5VV55|uniprotkb:Q5VV56|uniprotkb:Q66I33|uniprotkb:Q9V3W4|ensembl:ENSP00000254810|ensembl:ENSP00000355778|ensembl:ENSP00000355780|ensembl:ENSP00000355781|ensembl:ENSP00000465813|ensembl:ENSP00000466020|ensembl:ENSP00000468714|ensembl:ENSP00000499275|ensembl:ENSP00000499385|ensembl:ENSP00000499800	psi-mi:c4qz45_kompg(display_long)|uniprotkb:PAS_c121_0006(locus name)	psi-mi:h33_human(display_long)|uniprotkb:H3-3A(gene name)|psi-mi:H3-3A(display_short)|uniprotkb:H3-3B(gene name)|psi-mi:H3-3B(display_short)|uniprotkb:H3.3A(gene name synonym)|uniprotkb:H3.3B(gene name synonym)|uniprotkb:H3F3(gene name synonym)|uniprotkb:H3F3A(gene name synonym)|uniprotkb:H3F3B(gene name synonym)|uniprotkb:PP781(orf name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21272990|wwpdb:6IR9|emdb:EMD-9713|wwpdb:6J4X|emdb:EMD-0672|wwpdb:6J4Y|emdb:EMD-0673|wwpdb:6J4W|emdb:EMD-0671|wwpdb:6J51|emdb:EMD-0676|imex:IM-27000-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J51|ensemblfungi:CAY68519(transcript)|ensemblfungi:PAS_c121_0006(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|refseq:XP_002490799.1|interpro:IPR007808(Protein of unknown function DUF701, zinc-binding putative)|interpro:IPR038567	refseq:NP_002098.1|refseq:NP_005315.1|rcsb pdb:4H9N|rcsb pdb:3QL9|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4L58|rcsb pdb:4N4I|rcsb pdb:3WTP|rcsb pdb:4O62|rcsb pdb:4QQ4|rcsb pdb:4TMP|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4U7T|rcsb pdb:4GNG|rcsb pdb:4W5A|rcsb pdb:4GU0|rcsb pdb:4GUR|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:4GUS|rcsb pdb:4GY5|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5JA4|rcsb pdb:5JJY|ensembl:ENSG00000132475(gene)|ensembl:ENSG00000163041(gene)|rcsb pdb:5JLB|rcsb pdb:5KDM|rcsb pdb:5X7X|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6HGT|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6J9J|rcsb pdb:6PZV|rcsb pdb:6QXZ|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6U04|rcsb pdb:7A08|reactome:R-HSA-427413|rcsb pdb:7CIZ|reactome:R-HSA-5250924|reactome:R-HSA-5334118|rcsb pdb:7CJ0|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7CWH|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-427359|reactome:R-HSA-427389|ensembl:ENST00000254810(transcript)|ensembl:ENST00000366813(transcript)|ensembl:ENST00000366815(transcript)|ensembl:ENST00000366816(transcript)|ensembl:ENST00000586607(transcript)|ensembl:ENST00000587560(transcript)|ensembl:ENST00000589599(transcript)|ensembl:ENST00000655399(transcript)|ensembl:ENST00000661429(transcript)|ensembl:ENST00000666609(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84243|rcsb pdb:2L43|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3AV2|rcsb pdb:3JVK|rcsb pdb:3MUK|rcsb pdb:3MUL|dip:DIP-40046N	-	-	-	figure legend:Figs. 1 and S5 and S6, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:RkWbUdsBYdChoYY7PNim4W09k0w644223	rogid:cRqA5/IBNfIbbxAnbwLqzXip20I9606	rigid:bu2fRSb5w1xmr1TmgmuuE/ZxEX0	false	-	-	1	2	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZ45	uniprotkb:P62805	intact:EBI-21272934|ensemblfungi:CAY68519	intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567	psi-mi:c4qz45_kompg(display_long)|uniprotkb:PAS_c121_0006(locus name)	psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21272990|wwpdb:6IR9|emdb:EMD-9713|wwpdb:6J4X|emdb:EMD-0672|wwpdb:6J4Y|emdb:EMD-0673|wwpdb:6J4W|emdb:EMD-0671|wwpdb:6J51|emdb:EMD-0676|imex:IM-27000-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J51|ensemblfungi:CAY68519(transcript)|ensemblfungi:PAS_c121_0006(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|refseq:XP_002490799.1|interpro:IPR007808(Protein of unknown function DUF701, zinc-binding putative)|interpro:IPR038567	ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225	-	-	-	figure legend:Figs. 1 and S5 and S6, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:RkWbUdsBYdChoYY7PNim4W09k0w644223	rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606	rigid:bu2fRSb5w1xmr1TmgmuuE/ZxEX0	false	-	-	1	2	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:C4R009	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20800218|ensemblfungi:CAY68833	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:c4r009_kompg(display_long)|uniprotkb:PAS_chr2-1_0223(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21273043|wwpdb:6J4Z|emdb:EMD-0674|wwpdb:6J50|emdb:EMD-0675|imex:IM-27000-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	rcsb pdb:6IR9|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY68833(transcript)|ensemblfungi:PAS_chr2-1_0223(gene)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0001056"(RNA polymerase III activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:6INQ|refseq:XP_002491113.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR023580|interpro:IPR020789|interpro:IPR000268(RNA polymerases, N/8 Kd subunits)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. S12, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:1ay4K0OWVYfU09LaWaEKYqDEXuk644223	rigid:0fuUi+4L46ky/RrQzst5xPzLNQo	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:C4R0E6	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-21272943|ensemblfungi:CAY68970	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:c4r0e6_kompg(display_long)|uniprotkb:PAS_chr2-1_0350(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21273043|wwpdb:6J4Z|emdb:EMD-0674|wwpdb:6J50|emdb:EMD-0675|imex:IM-27000-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:PAS_chr2-1_0350(gene)|go:"GO:0000182"(rDNA binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0006342"|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|ensemblfungi:CAY68970(transcript)|refseq:XP_002491250.1|rcsb pdb:5XON|interpro:IPR029040|interpro:IPR009287(Transcription initiation Spt4)|interpro:IPR022800|interpro:IPR038510	-	-	-	figure legend:Figs. S12, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:ywCrJ9W9Xggw4QlYjFSer87BELk644223	rigid:0fuUi+4L46ky/RrQzst5xPzLNQo	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:C4R1V1	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20800134|ensemblfungi:CAY69475	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:c4r1v1_kompg(display_long)|uniprotkb:PAS_chr2-2_0434(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21273043|wwpdb:6J4Z|emdb:EMD-0674|wwpdb:6J50|emdb:EMD-0675|imex:IM-27000-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY69475(transcript)|ensemblfungi:PAS_chr2-2_0434(gene)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0001056"(RNA polymerase III activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:6INQ|refseq:XP_002491755.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR020708|interpro:IPR006110(RNA polymerase Rpb6)|interpro:IPR012293(RNA polymerase subunit, RPB6/omega)|interpro:IPR028363|interpro:IPR036161|interpro:IPR006111(DNA-directed RNA polymerase, 14 to 18 kDa subunit)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. S12, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:sOgXLbXs4iRGdaUFfb88ZVm1W98644223	rigid:0fuUi+4L46ky/RrQzst5xPzLNQo	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:C4R273	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20800178|ensemblfungi:CAY69597	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:c4r273_kompg(display_long)|uniprotkb:PAS_chr2-2_0309(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21273043|wwpdb:6J4Z|emdb:EMD-0674|wwpdb:6J50|emdb:EMD-0675|imex:IM-27000-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY69597(transcript)|ensemblfungi:PAS_chr2-2_0309(gene)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0001056"(RNA polymerase III activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:6INQ|refseq:XP_002491877.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR005570(RNA polymerase, Rpb8)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. S12, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:MnvasHhqga4MIKsh8kH1/bpM0wc644223	rigid:0fuUi+4L46ky/RrQzst5xPzLNQo	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:C4R2U9	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20800081|ensemblfungi:CAY69823	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:c4r2u9_kompg(display_long)|uniprotkb:PAS_chr2-2_0104(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21273043|wwpdb:6J4Z|emdb:EMD-0674|wwpdb:6J50|emdb:EMD-0675|imex:IM-27000-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|ensemblfungi:CAY69823(transcript)|ensemblfungi:PAS_chr2-2_0104(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|rcsb pdb:6INQ|refseq:XP_002492103.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR010997(HRDC-like)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR038324|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. S12, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:/017Xpkf83C3N7U8UYAXzDWDlv8644223	rigid:0fuUi+4L46ky/RrQzst5xPzLNQo	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:C4R370	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-21272973|ensemblfungi:CAY71204	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:c4r370_kompg(display_long)|uniprotkb:Chromatin elongation factor spt5(gene name synonym)|uniprotkb:transcription Elongation factor SPT5(gene name synonym)|uniprotkb:PAS_chr3_1136(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21273043|wwpdb:6J4Z|emdb:EMD-0674|wwpdb:6J50|emdb:EMD-0675|imex:IM-27000-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY71204(transcript)|ensemblfungi:PAS_chr3_1136(gene)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|refseq:XP_002493383.1|rcsb pdb:5XON|interpro:IPR005824(KOW)|interpro:IPR005100(Supt5 repeat)|interpro:IPR036735|interpro:IPR039385|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR039659|interpro:IPR022581|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR008991(Translation protein SH3-like)	-	-	-	figure legend:Figs. S12, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:fiReSF3elv/T+GigQdEyO6vkdHQ644223	rigid:0fuUi+4L46ky/RrQzst5xPzLNQo	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:C4R3P8	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20800108|ensemblfungi:CAY70112	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:c4r3p8_kompg(display_long)|uniprotkb:PAS_chr3_0157(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21273043|wwpdb:6J4Z|emdb:EMD-0674|wwpdb:6J50|emdb:EMD-0675|imex:IM-27000-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	rcsb pdb:6J50|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J51|ensemblfungi:CAY70112(transcript)|ensemblfungi:PAS_chr3_0157(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|rcsb pdb:6INQ|refseq:XP_002492363.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR036710|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR020608|interpro:IPR035913|interpro:IPR020609|interpro:IPR039531|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. S12, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:uvHyo3JNliA/f1LdlRdTrLHAhu8644223	rigid:0fuUi+4L46ky/RrQzst5xPzLNQo	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:C4R3Z5	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20800241|ensemblfungi:CAY70274	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:c4r3z5_kompg(display_long)|uniprotkb:PAS_chr3_0244(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21273043|wwpdb:6J4Z|emdb:EMD-0674|wwpdb:6J50|emdb:EMD-0675|imex:IM-27000-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY70274(transcript)|ensemblfungi:PAS_chr3_0244(gene)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0046983"(protein dimerization activity)|rcsb pdb:6INQ|refseq:XP_002492460.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR037685|interpro:IPR036603|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. S12, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:Bcxi1i7CjZerdkNw1zlStjnDbGA644223	rigid:0fuUi+4L46ky/RrQzst5xPzLNQo	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:C4R4Y0	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20799999|ensemblfungi:CAY70616	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:c4r4y0_kompg(display_long)|uniprotkb:PAS_chr3_0568(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21273043|wwpdb:6J4Z|emdb:EMD-0674|wwpdb:6J50|emdb:EMD-0675|imex:IM-27000-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	interpro:IPR042102|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY70616(transcript)|ensemblfungi:PAS_chr3_0568(gene)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002492795.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR038593|interpro:IPR038120|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. S12, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:/Iegq8f+rYdUcNLjKKqdngz4RxI644223	rigid:0fuUi+4L46ky/RrQzst5xPzLNQo	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:C4R7L2	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20800059|ensemblfungi:CAY71587	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:c4r7l2_kompg(display_long)|uniprotkb:PAS_chr4_0344(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21273043|wwpdb:6J4Z|emdb:EMD-0674|wwpdb:6J50|emdb:EMD-0675|imex:IM-27000-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY71587(transcript)|ensemblfungi:PAS_chr4_0344(gene)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|rcsb pdb:6INQ|refseq:XP_002493766.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. S12, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:aRUBPn6vT0brJH8ce/7n4CfRPV8644223	rigid:0fuUi+4L46ky/RrQzst5xPzLNQo	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:C4R9A1	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20800159|ensemblfungi:CAY72176	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:c4r9a1_kompg(display_long)|uniprotkb:PAS_chr4_0906(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21273043|wwpdb:6J4Z|emdb:EMD-0674|wwpdb:6J50|emdb:EMD-0675|imex:IM-27000-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY72176(transcript)|ensemblfungi:PAS_chr4_0906(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0010590"(regulation of septum digestion after cytokinesis)|go:"GO:0097394"(telomeric repeat-containing RNA transcription by RNA polymerase II)|rcsb pdb:6INQ|refseq:XP_002494355.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036898|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR003029(S1, RNA binding)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. S12, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:uE/3Z3mElfHD6zyWFofgkpflFOg644223	rigid:0fuUi+4L46ky/RrQzst5xPzLNQo	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:F2QMI1	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20800261|ensemblfungi:CCA36628	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:f2qmi1_kompc(display_long)|uniprotkb:RPC10(gene name)|psi-mi:RPC10(display_short)|uniprotkb:PP7435_Chr1-0476(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:981350(kompc)|taxid:981350("Komagataella phaffii (strain ATCC 76273 / CBS 7435 / CECT 11047 / NRRL Y-11430 / Wegner 21-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21273043|wwpdb:6J4Z|emdb:EMD-0674|wwpdb:6J50|emdb:EMD-0675|imex:IM-27000-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CCA36628(transcript)|ensemblfungi:PP7435_CHR1-0476(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|rcsb pdb:6INQ|rcsb pdb:5XOG|interpro:IPR006591(RNA polymerase Rbp10)|interpro:IPR029040|interpro:IPR039747|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. S12, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:XNaJRCB6Mz0dez4DoFiRGfxeoZA981350	rigid:0fuUi+4L46ky/RrQzst5xPzLNQo	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:F2QPE6	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20800198|ensemblfungi:CCA37274	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:f2qpe6_kompc(display_long)|uniprotkb:RPB9(gene name)|psi-mi:RPB9(display_short)|uniprotkb:PP7435_Chr1-1144(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:981350(kompc)|taxid:981350("Komagataella phaffii (strain ATCC 76273 / CBS 7435 / CECT 11047 / NRRL Y-11430 / Wegner 21-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21273043|wwpdb:6J4Z|emdb:EMD-0674|wwpdb:6J50|emdb:EMD-0675|imex:IM-27000-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CCA37274(transcript)|ensemblfungi:PP7435_CHR1-1144(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|rcsb pdb:6INQ|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|interpro:IPR019761|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR034012|interpro:IPR001222(Zinc finger, TFIIS-type)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Figs. S12, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:K8GCq9GcWsMRVlapEcuaLTOLJfc981350	rigid:0fuUi+4L46ky/RrQzst5xPzLNQo	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:P04908	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21273043|wwpdb:6J4Z|emdb:EMD-0674|wwpdb:6J50|emdb:EMD-0675|imex:IM-27000-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N	-	-	-	figure legend:Figs. S12, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:4Qno1mMYZB6FdNoojrzulWLVq849606	rigid:0fuUi+4L46ky/RrQzst5xPzLNQo	false	-	-	1	2	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:P06899	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-6150252|uniprotkb:B2R4J4|uniprotkb:O60816|ensembl:ENSP00000342886|ensembl:ENSP00000476136	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:h2b1j_human(display_long)|uniprotkb:H2BC11(gene name)|psi-mi:H2BC11(display_short)|uniprotkb:H2BFR(gene name synonym)|uniprotkb:HIST1H2BJ(gene name synonym)|uniprotkb:Histone H2B.1(gene name synonym)|uniprotkb:Histone H2B.r(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21273043|wwpdb:6J4Z|emdb:EMD-0674|wwpdb:6J50|emdb:EMD-0675|imex:IM-27000-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	refseq:NP_066402.2|dip:DIP-421N|ensembl:ENSG00000124635(gene)|ensembl:ENST00000339812(transcript)|ensembl:ENST00000607124(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P06899|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WAA|rcsb pdb:3WTP|rcsb pdb:4CAY|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5FUG|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5VEY|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6YOV|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7K5X|rcsb pdb:3WA9|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225	-	-	-	figure legend:Figs. S12, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:74GQlSjGG1Ez6Uog74VXPLryKBc9606	rigid:0fuUi+4L46ky/RrQzst5xPzLNQo	false	-	-	1	2	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:P84243	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-120658|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q5VV55|uniprotkb:Q5VV56|uniprotkb:Q66I33|uniprotkb:Q9V3W4|ensembl:ENSP00000254810|ensembl:ENSP00000355778|ensembl:ENSP00000355780|ensembl:ENSP00000355781|ensembl:ENSP00000465813|ensembl:ENSP00000466020|ensembl:ENSP00000468714|ensembl:ENSP00000499275|ensembl:ENSP00000499385|ensembl:ENSP00000499800	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:h33_human(display_long)|uniprotkb:H3-3A(gene name)|psi-mi:H3-3A(display_short)|uniprotkb:H3-3B(gene name)|psi-mi:H3-3B(display_short)|uniprotkb:H3.3A(gene name synonym)|uniprotkb:H3.3B(gene name synonym)|uniprotkb:H3F3(gene name synonym)|uniprotkb:H3F3A(gene name synonym)|uniprotkb:H3F3B(gene name synonym)|uniprotkb:PP781(orf name)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21273043|wwpdb:6J4Z|emdb:EMD-0674|wwpdb:6J50|emdb:EMD-0675|imex:IM-27000-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	refseq:NP_002098.1|refseq:NP_005315.1|rcsb pdb:4H9N|rcsb pdb:3QL9|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4L58|rcsb pdb:4N4I|rcsb pdb:3WTP|rcsb pdb:4O62|rcsb pdb:4QQ4|rcsb pdb:4TMP|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4U7T|rcsb pdb:4GNG|rcsb pdb:4W5A|rcsb pdb:4GU0|rcsb pdb:4GUR|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:4GUS|rcsb pdb:4GY5|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5JA4|rcsb pdb:5JJY|ensembl:ENSG00000132475(gene)|ensembl:ENSG00000163041(gene)|rcsb pdb:5JLB|rcsb pdb:5KDM|rcsb pdb:5X7X|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6HGT|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6J9J|rcsb pdb:6PZV|rcsb pdb:6QXZ|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6U04|rcsb pdb:7A08|reactome:R-HSA-427413|rcsb pdb:7CIZ|reactome:R-HSA-5250924|reactome:R-HSA-5334118|rcsb pdb:7CJ0|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7CWH|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-427359|reactome:R-HSA-427389|ensembl:ENST00000254810(transcript)|ensembl:ENST00000366813(transcript)|ensembl:ENST00000366815(transcript)|ensembl:ENST00000366816(transcript)|ensembl:ENST00000586607(transcript)|ensembl:ENST00000587560(transcript)|ensembl:ENST00000589599(transcript)|ensembl:ENST00000655399(transcript)|ensembl:ENST00000661429(transcript)|ensembl:ENST00000666609(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84243|rcsb pdb:2L43|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3AV2|rcsb pdb:3JVK|rcsb pdb:3MUK|rcsb pdb:3MUL|dip:DIP-40046N	-	-	-	figure legend:Figs. S12, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:cRqA5/IBNfIbbxAnbwLqzXip20I9606	rigid:0fuUi+4L46ky/RrQzst5xPzLNQo	false	-	-	1	2	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:P62805	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Ehara et al. (2019)	imex:IM-27000|pubmed:30733384	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21273043|wwpdb:6J4Z|emdb:EMD-0674|wwpdb:6J50|emdb:EMD-0675|imex:IM-27000-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225	-	-	-	figure legend:Figs. S12, Table S1 and S2|comment:Identifier F2QTN1 in PDB accession code 6J4W has been changed to C4R009 to be consistent with the rest of the PDB accession codes and since they code for the same protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/14	2019/03/15	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606	rigid:0fuUi+4L46ky/RrQzst5xPzLNQo	false	-	-	1	2	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)