#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P51149	uniprotkb:Q9BXW6	intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062|ensembl:ENSP00000501618|ensembl:ENSP00000502000|ensembl:ENSP00000502088|ensembl:ENSP00000502486	intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291	psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym)	psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Tong et al. (2018)	pubmed:30721249|imex:IM-27689	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21914048|imex:IM-27689-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004628.4|ensembl:ENSG00000075785(gene)|ensembl:ENST00000265062(transcript)|ensembl:ENST00000674589(transcript)|ensembl:ENST00000675342(transcript)|ensembl:ENST00000675497(transcript)|ensembl:ENST00000676214(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0019076"(viral release from host cell)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032419"(extrinsic component of lysosome membrane)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090382"(phagosome maturation)|go:"GO:0090383"(phagosome acidification)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1902586"(obsolete multi-organism intercellular transport)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905394"(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:6IYB|rcsb pdb:6WCW|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|rcsb pdb:3LAW|dip:DIP-39879N	refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1	-	-	-	figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/12	2019/07/12	rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606	rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606	rigid:oq4HX1xTCNDF7Tg40+CEbh4PqZ0	false	sufficient binding region:2-195(IPR005225)	sufficient binding region:5-152	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51149	uniprotkb:Q96NA2	intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062|ensembl:ENSP00000501618|ensembl:ENSP00000502000|ensembl:ENSP00000502088|ensembl:ENSP00000502486	intact:EBI-2856119|uniprotkb:B2RBQ8|uniprotkb:Q9BSL3|uniprotkb:Q71RE6|uniprotkb:Q9BYS3|ensembl:ENSP00000301336|ensembl:ENSP00000481849	psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym)	psi-mi:rilp_human(display_long)|uniprotkb:RILP(gene name)|psi-mi:RILP(display_short)|uniprotkb:PP10141(orf name)	psi-mi:"MI:0071"(molecular sieving)	Tong et al. (2018)	pubmed:30721249|imex:IM-27689	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21914066|imex:IM-27689-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004628.4|ensembl:ENSG00000075785(gene)|ensembl:ENST00000265062(transcript)|ensembl:ENST00000674589(transcript)|ensembl:ENST00000675342(transcript)|ensembl:ENST00000675497(transcript)|ensembl:ENST00000676214(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0019076"(viral release from host cell)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032419"(extrinsic component of lysosome membrane)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090382"(phagosome maturation)|go:"GO:0090383"(phagosome acidification)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1902586"(obsolete multi-organism intercellular transport)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905394"(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:6IYB|rcsb pdb:6WCW|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|rcsb pdb:3LAW|dip:DIP-39879N	refseq:NP_113618.2|dip:DIP-29458N|ensembl:ENSG00000167705(gene)|ensembl:ENSG00000274145(gene)|ensembl:ENST00000301336(transcript)|ensembl:ENST00000622136(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0015031"(protein transport)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070676"(intralumenal vesicle formation)|interpro:IPR019143|interpro:IPR021563|interpro:IPR034743|interpro:IPR034744|rcsb pdb:1YHN|reactome:R-HSA-2132295	-	-	crc64:1057A1DAC2FFED94	figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/12	2019/07/12	rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606	rogid:dBBOnpVleCSq8//uqicphTGykw09606	rigid:bOemPPKVC03nPkSIOUw5kj4b2B0	false	sufficient binding region:2-195(IPR005225)	sufficient binding region:242-320(IPR034744)	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BXW6	uniprotkb:P51149	intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291	intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062|ensembl:ENSP00000501618|ensembl:ENSP00000502000|ensembl:ENSP00000502088|ensembl:ENSP00000502486	psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym)	psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Tong et al. (2018)	pubmed:30721249|imex:IM-27689	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21914083|imex:IM-27689-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1	refseq:NP_004628.4|ensembl:ENSG00000075785(gene)|ensembl:ENST00000265062(transcript)|ensembl:ENST00000674589(transcript)|ensembl:ENST00000675342(transcript)|ensembl:ENST00000675497(transcript)|ensembl:ENST00000676214(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0019076"(viral release from host cell)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032419"(extrinsic component of lysosome membrane)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090382"(phagosome maturation)|go:"GO:0090383"(phagosome acidification)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1902586"(obsolete multi-organism intercellular transport)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905394"(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:6IYB|rcsb pdb:6WCW|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|rcsb pdb:3LAW|dip:DIP-39879N	-	-	-	figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/12	2019/07/12	rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606	rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606	rigid:u4Eddlran3NnaNNlWHrgKcHEaUE	false	sufficient binding region:5-152	sufficient binding region:2-195(IPR005225)	-	-	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BXW6	uniprotkb:Q96NA2	intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291	intact:EBI-2856119|uniprotkb:B2RBQ8|uniprotkb:Q9BSL3|uniprotkb:Q71RE6|uniprotkb:Q9BYS3|ensembl:ENSP00000301336|ensembl:ENSP00000481849	psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym)	psi-mi:rilp_human(display_long)|uniprotkb:RILP(gene name)|psi-mi:RILP(display_short)|uniprotkb:PP10141(orf name)	psi-mi:"MI:0071"(molecular sieving)	Tong et al. (2018)	pubmed:30721249|imex:IM-27689	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21914083|imex:IM-27689-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1	refseq:NP_113618.2|dip:DIP-29458N|ensembl:ENSG00000167705(gene)|ensembl:ENSG00000274145(gene)|ensembl:ENST00000301336(transcript)|ensembl:ENST00000622136(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0015031"(protein transport)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070676"(intralumenal vesicle formation)|interpro:IPR019143|interpro:IPR021563|interpro:IPR034743|interpro:IPR034744|rcsb pdb:1YHN|reactome:R-HSA-2132295	-	-	crc64:1057A1DAC2FFED94	figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/12	2019/07/12	rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606	rogid:dBBOnpVleCSq8//uqicphTGykw09606	rigid:u4Eddlran3NnaNNlWHrgKcHEaUE	false	sufficient binding region:5-152	sufficient binding region:242-320(IPR034744)	-	-	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51149	uniprotkb:Q9BXW6	intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062|ensembl:ENSP00000501618|ensembl:ENSP00000502000|ensembl:ENSP00000502088|ensembl:ENSP00000502486	intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291	psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym)	psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Tong et al. (2018)	pubmed:30721249|imex:IM-27689	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21914102|wwpdb:6iyb|imex:IM-27689-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004628.4|ensembl:ENSG00000075785(gene)|ensembl:ENST00000265062(transcript)|ensembl:ENST00000674589(transcript)|ensembl:ENST00000675342(transcript)|ensembl:ENST00000675497(transcript)|ensembl:ENST00000676214(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0019076"(viral release from host cell)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032419"(extrinsic component of lysosome membrane)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090382"(phagosome maturation)|go:"GO:0090383"(phagosome acidification)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1902586"(obsolete multi-organism intercellular transport)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905394"(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:6IYB|rcsb pdb:6WCW|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|rcsb pdb:3LAW|dip:DIP-39879N	refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1	-	-	-	figure legend:Table 1, Fig. 2|3d-resolution:2.09A resolution|3d-r-factors:"Rwork: 0.195  Rfree: 0.232"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/12	2019/07/12	rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606	rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606	rigid:oq4HX1xTCNDF7Tg40+CEbh4PqZ0	false	sufficient binding region:2-195(IPR005225)|mutation:73-73	sufficient binding region:5-152	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BXW6	uniprotkb:P51149	intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291	intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062|ensembl:ENSP00000501618|ensembl:ENSP00000502000|ensembl:ENSP00000502088|ensembl:ENSP00000502486	psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym)	psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Tong et al. (2018)	pubmed:30721249|imex:IM-27689	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21914117|imex:IM-27689-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1	refseq:NP_004628.4|ensembl:ENSG00000075785(gene)|ensembl:ENST00000265062(transcript)|ensembl:ENST00000674589(transcript)|ensembl:ENST00000675342(transcript)|ensembl:ENST00000675497(transcript)|ensembl:ENST00000676214(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0019076"(viral release from host cell)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032419"(extrinsic component of lysosome membrane)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090382"(phagosome maturation)|go:"GO:0090383"(phagosome acidification)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1902586"(obsolete multi-organism intercellular transport)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905394"(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:6IYB|rcsb pdb:6WCW|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|rcsb pdb:3LAW|dip:DIP-39879N	-	-	-	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:5.0x10^-6(molar)	2019/07/12	2020/02/24	rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606	rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606	rigid:u4Eddlran3NnaNNlWHrgKcHEaUE	false	sufficient binding region:5-233	sufficient binding region:2-195(IPR005225)	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BXW6	uniprotkb:Q96NA2	intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291	intact:EBI-2856119|uniprotkb:B2RBQ8|uniprotkb:Q9BSL3|uniprotkb:Q71RE6|uniprotkb:Q9BYS3|ensembl:ENSP00000301336|ensembl:ENSP00000481849	psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym)	psi-mi:rilp_human(display_long)|uniprotkb:RILP(gene name)|psi-mi:RILP(display_short)|uniprotkb:PP10141(orf name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Tong et al. (2018)	pubmed:30721249|imex:IM-27689	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21914117|imex:IM-27689-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1	refseq:NP_113618.2|dip:DIP-29458N|ensembl:ENSG00000167705(gene)|ensembl:ENSG00000274145(gene)|ensembl:ENST00000301336(transcript)|ensembl:ENST00000622136(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0015031"(protein transport)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070676"(intralumenal vesicle formation)|interpro:IPR019143|interpro:IPR021563|interpro:IPR034743|interpro:IPR034744|rcsb pdb:1YHN|reactome:R-HSA-2132295	-	-	crc64:1057A1DAC2FFED94	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:5.0x10^-6(molar)	2019/07/12	2020/02/24	rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606	rogid:dBBOnpVleCSq8//uqicphTGykw09606	rigid:u4Eddlran3NnaNNlWHrgKcHEaUE	false	sufficient binding region:5-233	sufficient binding region:242-320(IPR034744)	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51149	uniprotkb:Q9BXW6	intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062|ensembl:ENSP00000501618|ensembl:ENSP00000502000|ensembl:ENSP00000502088|ensembl:ENSP00000502486	intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291	psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym)	psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Tong et al. (2018)	pubmed:30721249|imex:IM-27689	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21914140|imex:IM-27689-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004628.4|ensembl:ENSG00000075785(gene)|ensembl:ENST00000265062(transcript)|ensembl:ENST00000674589(transcript)|ensembl:ENST00000675342(transcript)|ensembl:ENST00000675497(transcript)|ensembl:ENST00000676214(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0019076"(viral release from host cell)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032419"(extrinsic component of lysosome membrane)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090382"(phagosome maturation)|go:"GO:0090383"(phagosome acidification)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1902586"(obsolete multi-organism intercellular transport)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905394"(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:6IYB|rcsb pdb:6WCW|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|rcsb pdb:3LAW|dip:DIP-39879N	refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1	-	-	-	figure legend:Fig. 3B|comment:OSBPL1A binds RAB7A when either GTP or GDP-loaded|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:9.3x10^-6(molar)	2019/07/12	2019/07/12	rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606	rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606	rigid:oq4HX1xTCNDF7Tg40+CEbh4PqZ0	false	sufficient binding region:2-195(IPR005225)|mutation with no effect:22-22	sufficient binding region:5-152|mutation disrupting interaction strength:58-58	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)