#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O75955 uniprotkb:P54852 intact:EBI-603643|ensembl:ENSP00000365569|ensembl:ENSP00000372873|ensembl:ENSP00000373056|ensembl:ENSP00000388861|ensembl:ENSP00000391438|uniprotkb:Q969J8|uniprotkb:Q9UHW1|uniprotkb:Q9UNV8|uniprotkb:B4DVY7 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 psi-mi:flot1_human(display_long)|uniprotkb:FLOT1(gene name)|psi-mi:FLOT1(display_short) psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21194669|imex:IM-26804-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001931"(uropod)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007409"(axonogenesis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030027"(lamellipodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033227"(dsRNA transport)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044854"(plasma membrane raft assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1901890"(positive regulation of cell junction assembly)|go:"GO:1903044"(protein localization to membrane raft)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR036013|mint:O75955|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8849932|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000137312(gene)|ensembl:ENSG00000206379(gene)|ensembl:ENSG00000206480(gene)|ensembl:ENSG00000230143(gene)|ensembl:ENSG00000232280(gene)|ensembl:ENST00000376389(transcript)|ensembl:ENST00000383382(transcript)|ensembl:ENST00000383562(transcript)|ensembl:ENST00000436822(transcript)|ensembl:ENST00000444632(transcript)|refseq:NP_005794.1|refseq:NP_001305804.1|refseq:XP_005248837.1 refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) - - - figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2019/01/09 2019/02/06 rogid:wRw9QYIRNJb0ZQtwjm/D+ydci8k9606 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rigid:zE8Km8T/DvBlBQ+MLa0/+1yatnM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BUP3 uniprotkb:P54852 intact:EBI-13625358|ensembl:ENSP00000387876|ensembl:ENSP00000394259|ensembl:ENSP00000397752|uniprotkb:A8K7S7|uniprotkb:D3DQY8|uniprotkb:O15383|uniprotkb:O60520|uniprotkb:O95345|uniprotkb:Q53GC1|uniprotkb:Q53GG2|uniprotkb:Q6IBI3 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 psi-mi:htai2_human(display_long)|uniprotkb:HTATIP2(gene name)|psi-mi:HTATIP2(display_short)|uniprotkb:30 kDa HIV-1 TAT-interacting protein(gene name synonym)|uniprotkb:CC3(gene name synonym)|uniprotkb:HIV-1 TAT-interactive protein 2(gene name synonym)|uniprotkb:TIP30(gene name synonym) psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21194685|imex:IM-26804-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109854(gene)|ensembl:ENST00000421577(transcript)|ensembl:ENST00000443524(transcript)|ensembl:ENST00000451739(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051170"(import into nucleus)|interpro:IPR016040("NAD(P)-binding")|interpro:IPR036291|rcsb pdb:2BKA|refseq:NP_001091990.1|refseq:NP_001091991.1|refseq:NP_001091992.1|refseq:NP_001091993.1|refseq:NP_006401.3 refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) - - - figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2019/01/09 2019/02/06 rogid:QbLj0k3EWp4OjupRpDV0eLZHpY09606 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rigid:c68mC007Fo0+lUmacUEFIbcJycw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P26678 uniprotkb:P54852 intact:EBI-692836|ensembl:ENSP00000350132 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 psi-mi:ppla_human(display_long)|uniprotkb:PLN(gene name)|psi-mi:PLN(display_short)|uniprotkb:PLB(gene name synonym) psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21194689|imex:IM-26804-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002658.1|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032868"(response to insulin)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033574"(response to testosterone)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051117"(ATPase binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055119"(relaxation of cardiac muscle)|ensembl:ENSG00000198523(gene)|ensembl:ENST00000357525(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008015"(blood circulation)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0031982"(vesicle)|dip:DIP-33582N|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086023"(adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086092"(regulation of the force of heart contraction by cardiac conduction)|go:"GO:0090281"(negative regulation of calcium ion import)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1901877"(negative regulation of calcium ion binding)|go:"GO:1901894"(regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1901895"(negative regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1902081"(negative regulation of calcium ion import into sarcoplasmic reticulum)|interpro:IPR005984(Phospholamban)|rcsb pdb:1K9N|rcsb pdb:1KCH|rcsb pdb:1PLN|rcsb pdb:1PLP|rcsb pdb:1PSL|rcsb pdb:1ZLL|rcsb pdb:2HYN|rcsb pdb:6Y40|reactome:R-HSA-5578775|reactome:R-HSA-936837 refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) - - - figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2019/01/09 2019/02/06 rogid:Ez0SC8EfE4K9O9JI5wNGAHJUXOw9606 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rigid:O4a2Er86wNR2CNDR9NZjkQZhhco false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q04941 uniprotkb:P54852 intact:EBI-608347|ensembl:ENSP00000365505|uniprotkb:A6NDT7|uniprotkb:Q32MM8 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 psi-mi:plp2_human(display_long)|uniprotkb:Intestinal membrane A4 protein(gene name synonym)|uniprotkb:Differentiation-dependent protein A4(gene name synonym)|uniprotkb:PLP2(gene name)|psi-mi:PLP2(display_short)|uniprotkb:A4(gene name synonym) psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21194693|imex:IM-26804-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102007(gene)|ensembl:ENST00000376327(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006935"(chemotaxis)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019956"(chemokine binding)|interpro:IPR008253(Marvel)|refseq:NP_002659.1 refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) - - - figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2019/01/09 2019/02/06 rogid:mQOlRVDVw9W4XWAzftif1tnKEdU9606 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rigid:2h8wjvjOqZynad9GiVWAapJJy/4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96DZ9 uniprotkb:P54852 intact:EBI-2548702|ensembl:ENSP00000344819|uniprotkb:E9PH91|uniprotkb:Q5PY48 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 psi-mi:cklf5_human(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym) psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21194697|imex:IM-26804-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166091(gene)|ensembl:ENST00000339180(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045662"(negative regulation of myoblast differentiation)|interpro:IPR008253(Marvel)|mint:Q96DZ9|go:"GO:0006935"(chemotaxis)|refseq:NP_001032365.1|refseq:NP_612469.1|refseq:NP_001275673.1|refseq:NP_001275674.1|refseq:NP_001275675.1|refseq:XP_016876442.1|refseq:XP_016876443.1 refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) - - - figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2019/01/09 2019/02/06 rogid:EGqSw7EqPjSoBwDYC7Td1f0PbCA9606 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rigid:EDm5U8IogCPaasLkoKaohUAgkqM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15836 uniprotkb:P54852 intact:EBI-722343|uniprotkb:Q9BRV4|ensembl:ENSP00000054666 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 psi-mi:vamp3_human(display_long)|uniprotkb:Synaptobrevin-3(gene name synonym)|uniprotkb:Cellubrevin(gene name synonym)|uniprotkb:VAMP3(gene name)|psi-mi:VAMP3(display_short)|uniprotkb:SYB3(gene name synonym) psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21194701|imex:IM-26804-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004772.1|dip:DIP-56422N|ensembl:ENSG00000049245(gene)|ensembl:ENST00000054666(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1903531"(negative regulation of secretion by cell)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|mint:Q15836|reactome:R-HSA-1236974|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034 refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) - - - figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2019/01/09 2019/02/06 rogid:JeCaIwh36OpRqMG0MFnpFZyN6jU9606 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rigid:LWjtwOB+pteNLhH6viJkaJ5btnw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NW97 uniprotkb:P54852 intact:EBI-726044|uniprotkb:A8K819|intact:EBI-28982784|ensembl:ENSP00000365176|ensembl:ENSP00000365182|ensembl:ENSP00000383600|ensembl:ENSP00000394899 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 psi-mi:tmm51_human(display_long)|uniprotkb:TMEM51(gene name)|psi-mi:TMEM51(display_short)|uniprotkb:C1orf72(gene name synonym) psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21194705|imex:IM-26804-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129688.1|refseq:NP_001129689.1|refseq:NP_001129690.1|refseq:NP_060492.1|ensembl:ENSP00000365176|ensembl:ENSP00000365182|ensembl:ENSP00000383600|ensembl:ENSP00000394899|refseq:XP_011539978.1|refseq:NP_001306594.1|refseq:XP_005245976.1|ensembl:ENSG00000171729(gene)|ensembl:ENST00000376008(transcript)|ensembl:ENST00000376014(transcript)|ensembl:ENST00000400796(transcript)|ensembl:ENST00000428417(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR029265|refseq:XP_016857079.1 refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) - - - figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2019/01/09 2019/02/06 rogid:D+zPUZqRR9fLJ2nvkP/jFdArrR89606 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rigid:jpPlwHClR5h9ffpe1cNDFpTyVnM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NW68 uniprotkb:P54852 intact:EBI-721848|uniprotkb:B4DMS7|uniprotkb:B4DTP7|uniprotkb:B4E2X8|uniprotkb:Q49AT8|uniprotkb:Q68DY6|uniprotkb:Q6IAA3|uniprotkb:Q6MZK1|uniprotkb:Q6UXS1|uniprotkb:Q9HAL9|uniprotkb:B4DTI7|ensembl:ENSP00000412173 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 psi-mi:bsdc1_human(display_long)|uniprotkb:BSDC1(gene name)|psi-mi:BSDC1(display_short)|uniprotkb:UNQ2494/PRO5781(orf name) psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21194709|imex:IM-26804-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137360.1|refseq:NP_001137361.1|refseq:NP_001137362.1|refseq:NP_060515.3|refseq:NP_001287887.1|ensembl:ENSG00000160058(gene)|ensembl:ENST00000455895(transcript)|interpro:IPR005607(BSD)|interpro:IPR035925|mint:Q9NW68 refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) - - - figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2019/01/09 2019/02/06 rogid:xURI5Azk5thRty0BOh6UyxlbB4Y9606 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rigid:PzV0ZrvjtjhhnBB1OpDEjb7c8K8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P10114 uniprotkb:P54852 intact:EBI-602366|uniprotkb:Q5JSC1|uniprotkb:Q5JSC2|uniprotkb:B2RCJ1|ensembl:ENSP00000245304 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 psi-mi:rap2a_human(display_long)|uniprotkb:RbBP-30(gene name synonym)|uniprotkb:RAP2A(gene name)|psi-mi:RAP2A(display_short) psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21194713|imex:IM-26804-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066361.1|ensembl:ENSG00000125249(gene)|ensembl:ENST00000245304(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035690"|go:"GO:0045184"(establishment of protein localization)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR041840|rcsb pdb:1KAO|rcsb pdb:2RAP|rcsb pdb:3RAP refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) - - - figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2019/01/09 2019/02/06 rogid:nPfR7R1+uJMxrtR91wD8gx/DKLY9606 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rigid:zrXhkVD6uAwPLZ4MtlK4Bm63dSI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P61026 uniprotkb:P54852 intact:EBI-726075|uniprotkb:O88386|uniprotkb:Q6IA52|uniprotkb:Q9D7X6|uniprotkb:Q9H0T3|uniprotkb:D6W538|ensembl:ENSP00000264710 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 psi-mi:rab10_human(display_long)|uniprotkb:RAB10(gene name)|psi-mi:RAB10(display_short) psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21194717|imex:IM-26804-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057215.3|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031489"(myosin V binding)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0097051"(establishment of protein localization to endoplasmic reticulum membrane)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:5LPN|rcsb pdb:5SZJ|reactome:R-HSA-1445148|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000084733(gene)|ensembl:ENST00000264710(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium) refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) - - - figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2019/01/09 2019/02/06 rogid:ZbfLtWtXl3z6/MYyhiZp6P1Y5tE9606 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rigid:cdOnU3vZ032bIgBJIJ4crNR7Gfk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NW68 uniprotkb:P54852 intact:EBI-721848|uniprotkb:B4DMS7|uniprotkb:B4DTP7|uniprotkb:B4E2X8|uniprotkb:Q49AT8|uniprotkb:Q68DY6|uniprotkb:Q6IAA3|uniprotkb:Q6MZK1|uniprotkb:Q6UXS1|uniprotkb:Q9HAL9|uniprotkb:B4DTI7|ensembl:ENSP00000412173 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 psi-mi:bsdc1_human(display_long)|uniprotkb:BSDC1(gene name)|psi-mi:BSDC1(display_short)|uniprotkb:UNQ2494/PRO5781(orf name) psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-21194735|imex:IM-26804-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137360.1|refseq:NP_001137361.1|refseq:NP_001137362.1|refseq:NP_060515.3|refseq:NP_001287887.1|ensembl:ENSG00000160058(gene)|ensembl:ENST00000455895(transcript)|interpro:IPR005607(BSD)|interpro:IPR035925|mint:Q9NW68 refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) - - - figure legend:suppl fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-c32)|taxid:9606("C32 melanoma cell line, amelanotic (colourless)") - 2019/01/09 2019/02/06 rogid:xURI5Azk5thRty0BOh6UyxlbB4Y9606 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rigid:PzV0ZrvjtjhhnBB1OpDEjb7c8K8 false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P61026 uniprotkb:P54852 intact:EBI-726075|uniprotkb:O88386|uniprotkb:Q6IA52|uniprotkb:Q9D7X6|uniprotkb:Q9H0T3|uniprotkb:D6W538|ensembl:ENSP00000264710 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 psi-mi:rab10_human(display_long)|uniprotkb:RAB10(gene name)|psi-mi:RAB10(display_short) psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-21194739|imex:IM-26804-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057215.3|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031489"(myosin V binding)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0097051"(establishment of protein localization to endoplasmic reticulum membrane)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:5LPN|rcsb pdb:5SZJ|reactome:R-HSA-1445148|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000084733(gene)|ensembl:ENST00000264710(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium) refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) - - - figure legend:suppl fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-c32)|taxid:9606("C32 melanoma cell line, amelanotic (colourless)") - 2019/01/09 2019/02/06 rogid:ZbfLtWtXl3z6/MYyhiZp6P1Y5tE9606 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rigid:cdOnU3vZ032bIgBJIJ4crNR7Gfk false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q9BUP3 uniprotkb:P54852 intact:EBI-13625358|ensembl:ENSP00000387876|ensembl:ENSP00000394259|ensembl:ENSP00000397752|uniprotkb:A8K7S7|uniprotkb:D3DQY8|uniprotkb:O15383|uniprotkb:O60520|uniprotkb:O95345|uniprotkb:Q53GC1|uniprotkb:Q53GG2|uniprotkb:Q6IBI3 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 psi-mi:htai2_human(display_long)|uniprotkb:HTATIP2(gene name)|psi-mi:HTATIP2(display_short)|uniprotkb:30 kDa HIV-1 TAT-interacting protein(gene name synonym)|uniprotkb:CC3(gene name synonym)|uniprotkb:HIV-1 TAT-interactive protein 2(gene name synonym)|uniprotkb:TIP30(gene name synonym) psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-21194743|imex:IM-26804-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109854(gene)|ensembl:ENST00000421577(transcript)|ensembl:ENST00000443524(transcript)|ensembl:ENST00000451739(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051170"(import into nucleus)|interpro:IPR016040("NAD(P)-binding")|interpro:IPR036291|rcsb pdb:2BKA|refseq:NP_001091990.1|refseq:NP_001091991.1|refseq:NP_001091992.1|refseq:NP_001091993.1|refseq:NP_006401.3 refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) - - - figure legend:fig 4a suppl fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-c32)|taxid:9606("C32 melanoma cell line, amelanotic (colourless)") - 2019/01/09 2019/02/06 rogid:QbLj0k3EWp4OjupRpDV0eLZHpY09606 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rigid:c68mC007Fo0+lUmacUEFIbcJycw false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q04941 uniprotkb:P54852 intact:EBI-608347|ensembl:ENSP00000365505|uniprotkb:A6NDT7|uniprotkb:Q32MM8 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 psi-mi:plp2_human(display_long)|uniprotkb:Intestinal membrane A4 protein(gene name synonym)|uniprotkb:Differentiation-dependent protein A4(gene name synonym)|uniprotkb:PLP2(gene name)|psi-mi:PLP2(display_short)|uniprotkb:A4(gene name synonym) psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-21194747|imex:IM-26804-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102007(gene)|ensembl:ENST00000376327(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006935"(chemotaxis)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019956"(chemokine binding)|interpro:IPR008253(Marvel)|refseq:NP_002659.1 refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) - - - figure legend:fig 4a; suppl fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-c32)|taxid:9606("C32 melanoma cell line, amelanotic (colourless)") - 2019/01/09 2019/02/06 rogid:mQOlRVDVw9W4XWAzftif1tnKEdU9606 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rigid:2h8wjvjOqZynad9GiVWAapJJy/4 false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P54852 uniprotkb:O75955 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 intact:EBI-603643|ensembl:ENSP00000365569|ensembl:ENSP00000372873|ensembl:ENSP00000373056|ensembl:ENSP00000388861|ensembl:ENSP00000391438|uniprotkb:Q969J8|uniprotkb:Q9UHW1|uniprotkb:Q9UNV8|uniprotkb:B4DVY7 psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:flot1_human(display_long)|uniprotkb:FLOT1(gene name)|psi-mi:FLOT1(display_short) psi-mi:"MI:0813"(proximity ligation assay) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-21195467|imex:IM-26804-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001931"(uropod)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007409"(axonogenesis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030027"(lamellipodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033227"(dsRNA transport)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044854"(plasma membrane raft assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1901890"(positive regulation of cell junction assembly)|go:"GO:1903044"(protein localization to membrane raft)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR036013|mint:O75955|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8849932|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000137312(gene)|ensembl:ENSG00000206379(gene)|ensembl:ENSG00000206480(gene)|ensembl:ENSG00000230143(gene)|ensembl:ENSG00000232280(gene)|ensembl:ENST00000376389(transcript)|ensembl:ENST00000383382(transcript)|ensembl:ENST00000383562(transcript)|ensembl:ENST00000436822(transcript)|ensembl:ENST00000444632(transcript)|refseq:NP_005794.1|refseq:NP_001305804.1|refseq:XP_005248837.1 - - - figure legend:fig 4a, suppl fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-c32)|taxid:9606("C32 melanoma cell line, amelanotic (colourless)") - 2019/01/09 2019/02/07 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rogid:wRw9QYIRNJb0ZQtwjm/D+ydci8k9606 rigid:zE8Km8T/DvBlBQ+MLa0/+1yatnM false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P54852 uniprotkb:P10114 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 intact:EBI-602366|uniprotkb:Q5JSC1|uniprotkb:Q5JSC2|uniprotkb:B2RCJ1|ensembl:ENSP00000245304 psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:rap2a_human(display_long)|uniprotkb:RbBP-30(gene name synonym)|uniprotkb:RAP2A(gene name)|psi-mi:RAP2A(display_short) psi-mi:"MI:0813"(proximity ligation assay) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-21195471|imex:IM-26804-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) refseq:NP_066361.1|ensembl:ENSG00000125249(gene)|ensembl:ENST00000245304(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035690"|go:"GO:0045184"(establishment of protein localization)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR041840|rcsb pdb:1KAO|rcsb pdb:2RAP|rcsb pdb:3RAP - - - figure legend:fig 4a, suppl fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-c32)|taxid:9606("C32 melanoma cell line, amelanotic (colourless)") - 2019/01/09 2019/02/07 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rogid:nPfR7R1+uJMxrtR91wD8gx/DKLY9606 rigid:zrXhkVD6uAwPLZ4MtlK4Bm63dSI false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P54852 uniprotkb:Q96DZ9 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 intact:EBI-2548702|ensembl:ENSP00000344819|uniprotkb:E9PH91|uniprotkb:Q5PY48 psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:cklf5_human(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-21195475|imex:IM-26804-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) ensembl:ENSG00000166091(gene)|ensembl:ENST00000339180(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045662"(negative regulation of myoblast differentiation)|interpro:IPR008253(Marvel)|mint:Q96DZ9|go:"GO:0006935"(chemotaxis)|refseq:NP_001032365.1|refseq:NP_612469.1|refseq:NP_001275673.1|refseq:NP_001275674.1|refseq:NP_001275675.1|refseq:XP_016876442.1|refseq:XP_016876443.1 - - - figure legend:suppl fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-c32)|taxid:9606("C32 melanoma cell line, amelanotic (colourless)") - 2019/01/09 2019/02/07 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rogid:EGqSw7EqPjSoBwDYC7Td1f0PbCA9606 rigid:EDm5U8IogCPaasLkoKaohUAgkqM false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P54852 uniprotkb:Q15836 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 intact:EBI-722343|uniprotkb:Q9BRV4|ensembl:ENSP00000054666 psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:vamp3_human(display_long)|uniprotkb:Synaptobrevin-3(gene name synonym)|uniprotkb:Cellubrevin(gene name synonym)|uniprotkb:VAMP3(gene name)|psi-mi:VAMP3(display_short)|uniprotkb:SYB3(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-21195479|imex:IM-26804-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) refseq:NP_004772.1|dip:DIP-56422N|ensembl:ENSG00000049245(gene)|ensembl:ENST00000054666(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1903531"(negative regulation of secretion by cell)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|mint:Q15836|reactome:R-HSA-1236974|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034 - - - figure legend:suppl fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-c32)|taxid:9606("C32 melanoma cell line, amelanotic (colourless)") - 2019/01/09 2019/02/07 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rogid:JeCaIwh36OpRqMG0MFnpFZyN6jU9606 rigid:LWjtwOB+pteNLhH6viJkaJ5btnw false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P54852 uniprotkb:Q9NW97 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 intact:EBI-726044|uniprotkb:A8K819|intact:EBI-28982784|ensembl:ENSP00000365176|ensembl:ENSP00000365182|ensembl:ENSP00000383600|ensembl:ENSP00000394899 psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:tmm51_human(display_long)|uniprotkb:TMEM51(gene name)|psi-mi:TMEM51(display_short)|uniprotkb:C1orf72(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-21195483|imex:IM-26804-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) refseq:NP_001129688.1|refseq:NP_001129689.1|refseq:NP_001129690.1|refseq:NP_060492.1|ensembl:ENSP00000365176|ensembl:ENSP00000365182|ensembl:ENSP00000383600|ensembl:ENSP00000394899|refseq:XP_011539978.1|refseq:NP_001306594.1|refseq:XP_005245976.1|ensembl:ENSG00000171729(gene)|ensembl:ENST00000376008(transcript)|ensembl:ENST00000376014(transcript)|ensembl:ENST00000400796(transcript)|ensembl:ENST00000428417(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR029265|refseq:XP_016857079.1 - - - figure legend:suppl fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-c32)|taxid:9606("C32 melanoma cell line, amelanotic (colourless)") - 2019/01/09 2019/02/07 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rogid:D+zPUZqRR9fLJ2nvkP/jFdArrR89606 rigid:jpPlwHClR5h9ffpe1cNDFpTyVnM false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q9BUP3 uniprotkb:P54852 intact:EBI-13625358|ensembl:ENSP00000387876|ensembl:ENSP00000394259|ensembl:ENSP00000397752|uniprotkb:A8K7S7|uniprotkb:D3DQY8|uniprotkb:O15383|uniprotkb:O60520|uniprotkb:O95345|uniprotkb:Q53GC1|uniprotkb:Q53GG2|uniprotkb:Q6IBI3 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 psi-mi:htai2_human(display_long)|uniprotkb:HTATIP2(gene name)|psi-mi:HTATIP2(display_short)|uniprotkb:30 kDa HIV-1 TAT-interacting protein(gene name synonym)|uniprotkb:CC3(gene name synonym)|uniprotkb:HIV-1 TAT-interactive protein 2(gene name synonym)|uniprotkb:TIP30(gene name synonym) psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21195498|imex:IM-26804-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109854(gene)|ensembl:ENST00000421577(transcript)|ensembl:ENST00000443524(transcript)|ensembl:ENST00000451739(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051170"(import into nucleus)|interpro:IPR016040("NAD(P)-binding")|interpro:IPR036291|rcsb pdb:2BKA|refseq:NP_001091990.1|refseq:NP_001091991.1|refseq:NP_001091992.1|refseq:NP_001091993.1|refseq:NP_006401.3 refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) - - - figure legend:fig 4a suppl fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2019/01/09 2019/02/07 rogid:QbLj0k3EWp4OjupRpDV0eLZHpY09606 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rigid:c68mC007Fo0+lUmacUEFIbcJycw false - - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q04941 uniprotkb:P54852 intact:EBI-608347|ensembl:ENSP00000365505|uniprotkb:A6NDT7|uniprotkb:Q32MM8 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 psi-mi:plp2_human(display_long)|uniprotkb:Intestinal membrane A4 protein(gene name synonym)|uniprotkb:Differentiation-dependent protein A4(gene name synonym)|uniprotkb:PLP2(gene name)|psi-mi:PLP2(display_short)|uniprotkb:A4(gene name synonym) psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21195502|imex:IM-26804-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102007(gene)|ensembl:ENST00000376327(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006935"(chemotaxis)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019956"(chemokine binding)|interpro:IPR008253(Marvel)|refseq:NP_002659.1 refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) - - - figure legend:fig 4b; suppl fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2019/01/09 2019/02/07 rogid:mQOlRVDVw9W4XWAzftif1tnKEdU9606 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rigid:2h8wjvjOqZynad9GiVWAapJJy/4 false - - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P54852 uniprotkb:O75955 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 intact:EBI-603643|ensembl:ENSP00000365569|ensembl:ENSP00000372873|ensembl:ENSP00000373056|ensembl:ENSP00000388861|ensembl:ENSP00000391438|uniprotkb:Q969J8|uniprotkb:Q9UHW1|uniprotkb:Q9UNV8|uniprotkb:B4DVY7 psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:flot1_human(display_long)|uniprotkb:FLOT1(gene name)|psi-mi:FLOT1(display_short) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21195506|imex:IM-26804-52 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001931"(uropod)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007409"(axonogenesis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030027"(lamellipodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033227"(dsRNA transport)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044854"(plasma membrane raft assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1901890"(positive regulation of cell junction assembly)|go:"GO:1903044"(protein localization to membrane raft)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR036013|mint:O75955|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8849932|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000137312(gene)|ensembl:ENSG00000206379(gene)|ensembl:ENSG00000206480(gene)|ensembl:ENSG00000230143(gene)|ensembl:ENSG00000232280(gene)|ensembl:ENST00000376389(transcript)|ensembl:ENST00000383382(transcript)|ensembl:ENST00000383562(transcript)|ensembl:ENST00000436822(transcript)|ensembl:ENST00000444632(transcript)|refseq:NP_005794.1|refseq:NP_001305804.1|refseq:XP_005248837.1 - - - figure legend:fig 4a, suppl fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2019/01/09 2019/02/07 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rogid:wRw9QYIRNJb0ZQtwjm/D+ydci8k9606 rigid:zE8Km8T/DvBlBQ+MLa0/+1yatnM false - - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P54852 uniprotkb:P10114 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 intact:EBI-602366|uniprotkb:Q5JSC1|uniprotkb:Q5JSC2|uniprotkb:B2RCJ1|ensembl:ENSP00000245304 psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:rap2a_human(display_long)|uniprotkb:RbBP-30(gene name synonym)|uniprotkb:RAP2A(gene name)|psi-mi:RAP2A(display_short) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21195511|imex:IM-26804-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) refseq:NP_066361.1|ensembl:ENSG00000125249(gene)|ensembl:ENST00000245304(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035690"|go:"GO:0045184"(establishment of protein localization)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR041840|rcsb pdb:1KAO|rcsb pdb:2RAP|rcsb pdb:3RAP - - - figure legend:fig 4a, suppl fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2019/01/09 2019/02/07 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rogid:nPfR7R1+uJMxrtR91wD8gx/DKLY9606 rigid:zrXhkVD6uAwPLZ4MtlK4Bm63dSI false - - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P54852 uniprotkb:Q9NW97 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 intact:EBI-726044|uniprotkb:A8K819|intact:EBI-28982784|ensembl:ENSP00000365176|ensembl:ENSP00000365182|ensembl:ENSP00000383600|ensembl:ENSP00000394899 psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:tmm51_human(display_long)|uniprotkb:TMEM51(gene name)|psi-mi:TMEM51(display_short)|uniprotkb:C1orf72(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21195515|imex:IM-26804-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) refseq:NP_001129688.1|refseq:NP_001129689.1|refseq:NP_001129690.1|refseq:NP_060492.1|ensembl:ENSP00000365176|ensembl:ENSP00000365182|ensembl:ENSP00000383600|ensembl:ENSP00000394899|refseq:XP_011539978.1|refseq:NP_001306594.1|refseq:XP_005245976.1|ensembl:ENSG00000171729(gene)|ensembl:ENST00000376008(transcript)|ensembl:ENST00000376014(transcript)|ensembl:ENST00000400796(transcript)|ensembl:ENST00000428417(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR029265|refseq:XP_016857079.1 - - - figure legend:suppl fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2019/01/09 2019/02/07 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rogid:D+zPUZqRR9fLJ2nvkP/jFdArrR89606 rigid:jpPlwHClR5h9ffpe1cNDFpTyVnM false - - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P54852 uniprotkb:Q15836 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 intact:EBI-722343|uniprotkb:Q9BRV4|ensembl:ENSP00000054666 psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:vamp3_human(display_long)|uniprotkb:Synaptobrevin-3(gene name synonym)|uniprotkb:Cellubrevin(gene name synonym)|uniprotkb:VAMP3(gene name)|psi-mi:VAMP3(display_short)|uniprotkb:SYB3(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21195519|imex:IM-26804-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) refseq:NP_004772.1|dip:DIP-56422N|ensembl:ENSG00000049245(gene)|ensembl:ENST00000054666(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1903531"(negative regulation of secretion by cell)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|mint:Q15836|reactome:R-HSA-1236974|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034 - - - figure legend:suppl fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2019/01/09 2019/02/07 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rogid:JeCaIwh36OpRqMG0MFnpFZyN6jU9606 rigid:LWjtwOB+pteNLhH6viJkaJ5btnw false - - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9NW68 uniprotkb:P54852 intact:EBI-721848|uniprotkb:B4DMS7|uniprotkb:B4DTP7|uniprotkb:B4E2X8|uniprotkb:Q49AT8|uniprotkb:Q68DY6|uniprotkb:Q6IAA3|uniprotkb:Q6MZK1|uniprotkb:Q6UXS1|uniprotkb:Q9HAL9|uniprotkb:B4DTI7|ensembl:ENSP00000412173 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 psi-mi:bsdc1_human(display_long)|uniprotkb:BSDC1(gene name)|psi-mi:BSDC1(display_short)|uniprotkb:UNQ2494/PRO5781(orf name) psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21195523|imex:IM-26804-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137360.1|refseq:NP_001137361.1|refseq:NP_001137362.1|refseq:NP_060515.3|refseq:NP_001287887.1|ensembl:ENSG00000160058(gene)|ensembl:ENST00000455895(transcript)|interpro:IPR005607(BSD)|interpro:IPR035925|mint:Q9NW68 refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) - - - figure legend:suppl fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2019/01/09 2019/02/07 rogid:xURI5Azk5thRty0BOh6UyxlbB4Y9606 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rigid:PzV0ZrvjtjhhnBB1OpDEjb7c8K8 false - - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P54852 uniprotkb:Q96DZ9 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 intact:EBI-2548702|ensembl:ENSP00000344819|uniprotkb:E9PH91|uniprotkb:Q5PY48 psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:cklf5_human(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Christians et al. (2019) pubmed:30614533|imex:IM-26804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21237184|imex:IM-26804-54 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) ensembl:ENSG00000166091(gene)|ensembl:ENST00000339180(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045662"(negative regulation of myoblast differentiation)|interpro:IPR008253(Marvel)|mint:Q96DZ9|go:"GO:0006935"(chemotaxis)|refseq:NP_001032365.1|refseq:NP_612469.1|refseq:NP_001275673.1|refseq:NP_001275674.1|refseq:NP_001275675.1|refseq:XP_016876442.1|refseq:XP_016876443.1 - - - figure legend:suppl fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2019/01/09 2019/03/07 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 rogid:EGqSw7EqPjSoBwDYC7Td1f0PbCA9606 rigid:EDm5U8IogCPaasLkoKaohUAgkqM false - - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)