#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9BPX7-2 uniprotkb:Q5T9L3-1 intact:EBI-22081070|ensembl:ENSP00000413029 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:q9bpx7-2(display_long)|uniprotkb:C7orf25(gene name)|psi-mi:C7orf25(display_short) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22081057|imex:IM-27807-101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000136197(gene)|ensembl:ENST00000447342(transcript)|intact:EBI-718586(isoform-parent) ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:CoMr/aWYoDgwChC91ZNy/Uio/0M9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:RfE5R2OaUpuKK0Hzi1k4jbfVncw false sufficient binding region:298-436 sufficient binding region:493-541 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UHD1 uniprotkb:Q5T9L3-1 intact:EBI-2550959|ensembl:ENSP00000319255|ensembl:ENSP00000496744|uniprotkb:Q9H3D6|uniprotkb:Q8WVL9|uniprotkb:B2R6P8|uniprotkb:Q6IN49 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:chrd1_human(display_long)|uniprotkb:CHP1(gene name synonym)|uniprotkb:CHORD domain-containing protein 1(gene name synonym)|uniprotkb:CHORDC1(gene name)|psi-mi:CHORDC1(display_short)|uniprotkb:Protein morgana(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22081142|imex:IM-27807-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000110172(gene)|ensembl:ENSG00000285023(gene)|ensembl:ENST00000320585(transcript)|ensembl:ENST00000646618(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0043531"(ADP binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:2000299"(negative regulation of Rho-dependent protein serine/threonine kinase activity)|interpro:IPR007051(CHORD)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|rcsb pdb:2YRT|go:"GO:1900034"(regulation of cellular response to heat)|refseq:NP_001137545.1|refseq:NP_036256.2 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:hlLw4jieLbD+CRQ/Nav7CR+YlUY9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:sKP87bTkxP1qS4cvL3gHwmfw9i8 false - sufficient binding region:493-541 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NEZ4-3 uniprotkb:Q5T9L3-1 intact:EBI-22081190|ensembl:ENSP00000507485 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:q8nez4-3(display_long)|uniprotkb:KMT2C(gene name)|psi-mi:KMT2C(display_short)|uniprotkb:HALR(gene name synonym)|uniprotkb:KIAA1506(gene name synonym)|uniprotkb:MLL3(gene name synonym)|uniprotkb:Homologous to ALR protein(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 3(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22081182|imex:IM-27807-103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000682283(transcript)|ensembl:ENSG00000055609(gene)|intact:EBI-1042997(isoform-parent) ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - isoform-comment:No experimental confirmation available. - figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:U4goNcqmvCxXbCH+sYv4L9AWzoM9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:YhHIe/6FBW6hkKZg2ybuRep/9zk false sufficient binding region:4926-4964 sufficient binding region:493-541 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O96011 uniprotkb:Q5T9L3-1 intact:EBI-594824|uniprotkb:Q96ET2|uniprotkb:B3KN85|uniprotkb:B4DXH9|ensembl:ENSP00000358312 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:px11b_human(display_long)|uniprotkb:Peroxisomal biogenesis factor 11B(gene name synonym)|uniprotkb:Protein PEX11 homolog beta(gene name synonym)|uniprotkb:PEX11B(gene name)|psi-mi:PEX11B(display_short)|uniprotkb:Peroxin-11B(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22081213|imex:IM-27807-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003837.1|refseq:NP_001171724.1|ensembl:ENSG00000131779(gene)|ensembl:ENST00000369306(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044375"(regulation of peroxisome size)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-HSA-9603798 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:5/6FYSwT/s0zO+x+5vM73A1sCsA9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:+lz3tCKAr6MQWPndrbOTQRDd6vc false - sufficient binding region:493-541 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21796 uniprotkb:Q5T9L3-1 intact:EBI-354158|uniprotkb:Q5FVE7|uniprotkb:Q9UIQ5|uniprotkb:Q9UPL0|uniprotkb:B3KVK4|uniprotkb:D3DQ93|ensembl:ENSP00000265333|ensembl:ENSP00000378484|ensembl:ENSP00000378487 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:vdac1_human(display_long)|uniprotkb:VDAC1(gene name)|psi-mi:VDAC1(display_short)|uniprotkb:VDAC(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 1(gene name synonym)|uniprotkb:Plasmalemmal porin(gene name synonym)|uniprotkb:Porin 31HL(gene name synonym)|uniprotkb:Porin 31HM(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22084704|imex:IM-27807-105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003365.1|refseq:XP_005272132.1|refseq:XP_016865310.1|refseq:XP_016865311.1|refseq:XP_016865312.1|dip:DIP-32862N|ensembl:ENSG00000213585(gene)|ensembl:ENST00000265333(transcript)|ensembl:ENST00000395044(transcript)|ensembl:ENST00000395047(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006820"(anion transport)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097001"(ceramide binding)|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030270|mint:P21796|rcsb pdb:2JK4|rcsb pdb:2K4T|rcsb pdb:5JDP|rcsb pdb:5XDN|rcsb pdb:5XDO|rcsb pdb:6G6U|rcsb pdb:6G73|rcsb pdb:6TIQ|rcsb pdb:6TIR|reactome:R-HSA-1268020|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-70268|reactome:R-HSA-8949215 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:8Fqe6Ga3NmwwuICa4L45ga2i1nk9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:ho6hujzLUrKp8KWZr0ljDAY/h+U false sufficient binding region:34-95 sufficient binding region:493-541 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01518 uniprotkb:Q5T9L3-1 intact:EBI-2808398|ensembl:ENSP00000361878|ensembl:ENSP00000361883|ensembl:ENSP00000361891|uniprotkb:Q6I9U6|uniprotkb:Q5T0S2|uniprotkb:Q53HR7|uniprotkb:Q5T0S1 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:cap1_human(display_long)|uniprotkb:CAP1(gene name)|psi-mi:CAP1(display_short)|uniprotkb:CAP(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085414|imex:IM-27807-87 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131236(gene)|ensembl:ENST00000372792(transcript)|ensembl:ENST00000372797(transcript)|ensembl:ENST00000372805(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028415|interpro:IPR028417|go:"GO:0001667"(ameboidal-type cell migration)|interpro:IPR036222|interpro:IPR036223|mint:Q01518|rcsb pdb:1K8F|reactome:R-HSA-114608|reactome:R-HSA-428890|reactome:R-HSA-6798695|refseq:XP_011538811.1|refseq:XP_011538812.1|refseq:XP_011538813.1|refseq:XP_011538814.1|refseq:XP_011538815.1|refseq:XP_011538816.1|refseq:XP_011538817.1|refseq:NP_001099000.1|refseq:NP_006358.1|refseq:XP_016855556.1|refseq:XP_016855557.1|refseq:XP_016855558.1|refseq:XP_016855559.1|refseq:XP_016855560.1|refseq:XP_016855561.1|refseq:XP_005270425.1|dip:DIP-62063N ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - crc64:7789D1FAC0D1AB7B - figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:BXrQm0u+e0xVOl2b+A18GrZy5Eg9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:+OXz5YPd6N3Zwbw7o9Hnn1MwYzU false sufficient binding region:411-475 sufficient binding region:493-541 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BQI5 uniprotkb:Q5T9L3-1 intact:EBI-2690801|uniprotkb:Q6MZY6|uniprotkb:A6NLD1|uniprotkb:Q5VYE2|uniprotkb:A6NL81|uniprotkb:Q8IWC2|uniprotkb:Q68D76|uniprotkb:Q4LE32|uniprotkb:Q5VYE4|uniprotkb:Q5VYE3|ensembl:ENSP00000360076 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:sgip1_human(display_long)|uniprotkb:Endophilin-3-interacting protein(gene name synonym)|uniprotkb:SGIP1(gene name)|psi-mi:SGIP1(display_short) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22086812|imex:IM-27807-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006711037.1|refseq:NP_001295132.1|refseq:XP_016858000.1|refseq:XP_016858001.1|refseq:XP_016858023.1|refseq:XP_016858024.1|refseq:NP_115667.2|refseq:XP_005271321.1|refseq:XP_005271327.1|ensembl:ENSG00000118473(gene)|ensembl:ENST00000371037(transcript)|go:"GO:0002021"(response to dietary excess)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0008017"(microtubule binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097009"(energy homeostasis)|go:"GO:2000253"(positive regulation of feeding behavior)|interpro:IPR018808|interpro:IPR028565|interpro:IPR036168|interpro:IPR037984|mint:Q9BQI5|rcsb pdb:5AWR|rcsb pdb:5AWS|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:6A9Y|reactome:R-HSA-8856825|reactome:R-HSA-8856828 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:zFAutzD0AvL0d3TY1e1+TCO1vO09606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:frqjevxl/Z11oRqmwVG+dEEX3do false - sufficient binding region:493-541 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96B45 uniprotkb:Q5T9L3-1 intact:EBI-6151489|uniprotkb:C9K0X3|uniprotkb:B3KUW4|uniprotkb:B2R488|ensembl:ENSP00000342331|ensembl:ENSP00000358899 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:borc7_human(display_long)|uniprotkb:BORCS7(gene name)|psi-mi:BORCS7(display_short)|uniprotkb:C10orf32(gene name synonym)|uniprotkb:Diaskedin(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22084900|imex:IM-27807-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129672.1|refseq:NP_653192.2|ensembl:ENSG00000166275(gene)|ensembl:ENST00000339834(transcript)|ensembl:ENST00000369883(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0099078"(BORC complex)|interpro:IPR032143 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:nWmtuEe/BAme4MMt55fvFjyGNss9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:eHqiM9qL23NEYmOVSw7rnqN4aRw false sufficient binding region:1-77|nub:?-? cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P55087 uniprotkb:Q5T9L3-1 intact:EBI-10104898|uniprotkb:P78564|ensembl:ENSP00000372654|ensembl:ENSP00000500720 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:aqp4_human(display_long)|uniprotkb:AQP4(gene name)|psi-mi:AQP4(display_short)|uniprotkb:Mercurial-insensitive water channel(gene name synonym)|uniprotkb:WCH4(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22084999|imex:IM-27807-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001641.1|refseq:NP_004019.1|ensembl:ENSG00000171885(gene)|ensembl:ENST00000383168(transcript)|ensembl:ENST00000672188(transcript)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006833"(water transport)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0010008"(endosome membrane)|go:"GO:0015250"(water channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030104"(water homeostasis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097450"(astrocyte end-foot)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|interpro:IPR034294|rcsb pdb:3GD8|reactome:R-HSA-432040|reactome:R-HSA-432047|dip:DIP-48842N ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:emloJNSTB0zSwtP91cSKBBr4PA89606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:g8T9s/Y6VKE2rvXk6G339NmfOQs false nub:?-?|sufficient binding region:1-184 cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P08962 uniprotkb:Q5T9L3-1 intact:EBI-762053|uniprotkb:Q5TZP3|uniprotkb:Q9UCG6|uniprotkb:Q8N6Z9|uniprotkb:F8VZE2|ensembl:ENSP00000257857|ensembl:ENSP00000393502|ensembl:ENSP00000447730|ensembl:ENSP00000449337 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:cd63_human(display_long)|uniprotkb:Melanoma-associated antigen ME491(gene name synonym)|uniprotkb:Ocular melanoma-associated antigen(gene name synonym)|uniprotkb:OMA81H(gene name synonym)|uniprotkb:Granulophysin(gene name synonym)|uniprotkb:Tetraspanin-30(gene name synonym)|uniprotkb:Lysosomal-associated membrane protein 3(gene name synonym)|uniprotkb:CD63(gene name)|psi-mi:CD63(display_short)|uniprotkb:MLA1(gene name synonym)|uniprotkb:TSPAN30(gene name synonym)|uniprotkb:Lysosome integral membrane protein 1(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085210|imex:IM-27807-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001771.1|refseq:NP_001244330.1|refseq:NP_001244318.1|refseq:NP_001244319.1|refseq:NP_001244320.1|refseq:NP_001244329.1|refseq:NP_001254627.1|refseq:NP_001244321.1|ensembl:ENSG00000135404(gene)|ensembl:ENST00000257857(transcript)|go:"GO:1900746"(regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|interpro:IPR042028|mint:P08962|reactome:R-HSA-114608|reactome:R-HSA-6798695|go:"GO:0097487"(multivesicular body, internal vesicle)|ensembl:ENST00000420846(transcript)|ensembl:ENST00000549117(transcript)|ensembl:ENST00000552692(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016477"(cell migration)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048757"(pigment granule maturation)|go:"GO:0070062"(extracellular exosome) ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:stCGi5kkTMIdO84qSwjmjpUwwvs9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:ffJ6ujWLYAtlMzFrcBw/PmevhoI false nub:?-?|sufficient binding region:123-197 cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9P003 uniprotkb:Q5T9L3-1 intact:EBI-1044341|ensembl:ENSP00000420443|uniprotkb:Q9H0X8|uniprotkb:A8K1Q8|uniprotkb:B2R553 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:cnih4_human(display_long)|uniprotkb:CNIH4(gene name)|psi-mi:CNIH4(display_short)|uniprotkb:Cornichon family AMPA receptor auxiliary protein 4(gene name synonym)|uniprotkb:HSPC163(orf name) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085220|imex:IM-27807-107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000465271(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031730"(CCR5 chemokine receptor binding)|interpro:IPR003377(Cornichon)|ensembl:ENSG00000143771(gene)|refseq:NP_054903.1|refseq:NP_001264126.1 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:vKqBlBp/B2XQikBgv7RZH8IymEo9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:9bgmzDNuSacEjkXsoJDGkDKyCVM false nub:?-?|sufficient binding region:1-138 cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15125 uniprotkb:Q5T9L3-1 intact:EBI-3915253|uniprotkb:Q6IBI9|uniprotkb:Q6FGL3|ensembl:ENSP00000417052 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:ebp_human(display_long)|uniprotkb:EBP(gene name)|psi-mi:EBP(display_short)|uniprotkb:Cholestenol Delta-isomerase(gene name synonym)|uniprotkb:"Delta(8)-Delta(7) sterol isomerase"(gene name synonym)|uniprotkb:Emopamil-binding protein(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085230|imex:IM-27807-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006570.1|ensembl:ENSG00000147155(gene)|ensembl:ENST00000495186(transcript)|go:"GO:0000247"(C-8 sterol isomerase activity)|go:"GO:0001501"(skeletal system development)|go:"GO:0004769"(steroid delta-isomerase activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033489"(cholesterol biosynthetic process via desmosterol)|go:"GO:0033490"(cholesterol biosynthetic process via lathosterol)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0047750"(cholestenol delta-isomerase activity)|interpro:IPR007905(Emopamil-binding)|interpro:IPR033118|rcsb pdb:6OHT|rcsb pdb:6OHU|reactome:R-HSA-6807047|reactome:R-HSA-6807062 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:7XfeeD/twqYll0Hv4YuJUbmAVJ09606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:pmvcuLGrR4/ZDQASXWFAncGKbnI false nub:?-? cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NPA0 uniprotkb:Q5T9L3-1 intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085238|imex:IM-27807-121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:E4SLLC2dFVPKkpGiAGNlYfzuPp0 false nub:?-?|sufficient binding region:37-242 cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96D05 uniprotkb:Q5T9L3-1 intact:EBI-2548784|ensembl:ENSP00000362376 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:f241b_human(display_long)|uniprotkb:FAM241B(gene name)|psi-mi:FAM241B(display_short)|uniprotkb:C10orf35(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085248|imex:IM-27807-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171224(gene)|ensembl:ENST00000373279(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR027953|mint:Q96D05|refseq:XP_011537757.1|refseq:NP_660349.1|refseq:XP_005269663.1|refseq:XP_005269665.1|refseq:XP_016871325.1 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:2Iylns4G5knUSJCXAPnLUE9laUU9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:srpjoKZHsJUrcPQhwuuwBq+d0Aw false nub:?-? cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UN67 uniprotkb:Q5T9L3-1 intact:EBI-6308942|ensembl:ENSP00000239446|uniprotkb:Q96T99 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:pcdba_human(display_long)|uniprotkb:PCDHB10(gene name)|psi-mi:PCDHB10(display_short)|uniprotkb:UNQ1906/PRO4352(orf name) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085256|imex:IM-27807-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120324(gene)|ensembl:ENST00000239446(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0045202"(synapse)|interpro:IPR002126(Cadherin)|interpro:IPR013164(Cadherin, N-terminal)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR032455|refseq:NP_061753.1 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:eDBO6rRJdTj1TzDUyXxX+iDJywo9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:MfFvYxgXKRlP0ol+v1EU18ScP/E false nub:?-?|sufficient binding region:682-800 cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q01959 uniprotkb:Q5T9L3-1 intact:EBI-6661445|ensembl:ENSP00000270349|ensembl:ENSP00000479597|uniprotkb:A2RUN4|uniprotkb:Q14996 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:sc6a3_human(display_long)|uniprotkb:SLC6A3(gene name)|psi-mi:SLC6A3(display_short)|uniprotkb:DAT1(gene name synonym)|uniprotkb:Solute carrier family 6 member 3(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085266|imex:IM-27807-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0007626"(locomotory behavior)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0016600"(flotillin complex)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0010039"(response to iron ion)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|mint:Q01959|reactome:R-HSA-379401|reactome:R-HSA-442660|reactome:R-HSA-5619081|reactome:R-HSA-5660724|ensembl:ENSG00000142319(gene)|ensembl:ENSG00000276996(gene)|ensembl:ENST00000270349(transcript)|ensembl:ENST00000621716(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|refseq:NP_001035.1|dip:DIP-41827N ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:mQKSGpeovNv4Sg8T2E3A8rVB2aY9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:Yl3c2Gib5SvIg1+yr6+7V8NzwnI false nub:?-?|sufficient binding region:1-343 cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P48436 uniprotkb:Q5T9L3-1 intact:EBI-3920028|ensembl:ENSP00000245479|uniprotkb:Q53Y80 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:sox9_human(display_long)|uniprotkb:SOX9(gene name)|psi-mi:SOX9(display_short) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085276|imex:IM-27807-123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000125398(gene)|ensembl:ENST00000245479(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001503"(ossification)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001708"(cell fate specification)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001942"(hair follicle development)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002683"(negative regulation of immune system process)|go:"GO:0003170"(heart valve development)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003188"(heart valve formation)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003413"(chondrocyte differentiation involved in endochondral bone morphogenesis)|go:"GO:0003415"(chondrocyte hypertrophy)|go:"GO:0003430"(growth plate cartilage chondrocyte growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0014032"(neural crest cell development)|go:"GO:0014036"(neural crest cell fate specification)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0030850"(prostate gland development)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0030903"(notochord development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0035622"(intrahepatic bile duct development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046322"(negative regulation of fatty acid oxidation)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051216"(cartilage development)|go:"GO:0060008"(Sertoli cell differentiation)|go:"GO:0060009"(Sertoli cell development)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060174"(limb bud formation)|go:"GO:0060221"(retinal rod cell differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060517"(epithelial cell proliferation involved in prostatic bud elongation)|go:"GO:0060532"(bronchus cartilage development)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0060784"(regulation of cell proliferation involved in tissue homeostasis)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0061046"(regulation of branching involved in lung morphogenesis)|go:"GO:0061138"(morphogenesis of a branching epithelium)|go:"GO:0061145"(lung smooth muscle development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070384"(Harderian gland development)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071504"(cellular response to heparin)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0072034"(renal vesicle induction)|go:"GO:0072190"(ureter urothelium development)|go:"GO:0072193"(ureter smooth muscle cell differentiation)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0072289"(metanephric nephron tubule formation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090184"(positive regulation of kidney development)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:0097065"(anterior head development)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000020"(positive regulation of male gonad development)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|go:"GO:2000741"(positive regulation of mesenchymal stem cell differentiation)|go:"GO:2000794"(regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:2001054"(negative regulation of mesenchymal cell apoptotic process)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022151|interpro:IPR029548|interpro:IPR036910|rcsb pdb:1S9M|rcsb pdb:1SX9|rcsb pdb:4EUW|reactome:R-HSA-3769402|reactome:R-HSA-8878166|reactome:R-HSA-9690406|refseq:NP_000337.1|dip:DIP-61319N ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:9tMOPJUNgC89D1SdrN0b4yCXRUk9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:dpRl4yucgoJmiF1fEB4/s5LHZ40 false sufficient binding region:381-458|nub:?-? cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H6X4 uniprotkb:Q5T9L3-1 intact:EBI-22084643|uniprotkb:Q08AK4|uniprotkb:Q6PJN3|ensembl:ENSP00000312615 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:tm134_human(display_long)|uniprotkb:TMEM134(gene name)|psi-mi:TMEM134(display_short) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085286|imex:IM-27807-81 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001072118.1|refseq:NP_001072119.1|refseq:NP_079400.1|ensembl:ENSG00000172663(gene)|ensembl:ENST00000308022(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR008590(Protein of unknown function DUF872, eukaryotic)|interpro:IPR039714 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:lutWi4WCwdkEPwUXGiONGVN/xvY9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:Hc4jmXCgOST8sj0GjNZTGHYOVAo false sufficient binding region:1-165|nub:?-? cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y6G1 uniprotkb:Q5T9L3-1 intact:EBI-2800360|uniprotkb:B2R552|ensembl:ENSP00000211314 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:tm14a_human(display_long)|uniprotkb:C6orf73(gene name synonym)|uniprotkb:PTD011(orf name)|uniprotkb:TMEM14A(gene name)|psi-mi:TMEM14A(display_short) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085296|imex:IM-27807-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000211314(transcript)|refseq:NP_054770.1|ensembl:ENSG00000096092(gene)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|interpro:IPR005349(Protein of unknown function UPF0136, Transmembrane)|interpro:IPR044890|mint:Q9Y6G1|rcsb pdb:2LOO|rcsb pdb:2LOP|go:"GO:0005789"(endoplasmic reticulum membrane) ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:nrvzpoAjkgMJIDiqVIVa5b3jLsQ9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:boKV7iPAWf+PB+piwbDNFPA8Mvg false sufficient binding region:1-99|nub:?-? cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NX00 uniprotkb:Q5T9L3-1 intact:EBI-2514588|ensembl:ENSP00000253047|uniprotkb:Q9BU41 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:tm160_human(display_long)|uniprotkb:TMEM160(gene name)|psi-mi:TMEM160(display_short) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085306|imex:IM-27807-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130748(gene)|ensembl:ENST00000253047(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR026801|refseq:NP_060324.1 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:5PuVgGSb9lQAD5/1RS6csGdai0Q9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:kD+ZPFFOoMRy8zJLcW1rRQTeYeE false sufficient binding region:17-187|nub:?-? cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96A57 uniprotkb:Q5T9L3-1 intact:EBI-723971|uniprotkb:D3DVZ9|uniprotkb:Q0VGC8|uniprotkb:Q5TDS5|uniprotkb:Q96ES2|uniprotkb:Q9P0A7|uniprotkb:B2RDM8|ensembl:ENSP00000202834|ensembl:ENSP00000368579|ensembl:ENSP00000368581|ensembl:ENSP00000368585|ensembl:ENSP00000368588|ensembl:ENSP00000368601 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:tm230_human(display_long)|uniprotkb:TMEM230(gene name)|psi-mi:TMEM230(display_short)|uniprotkb:C20orf30(gene name synonym)|uniprotkb:HSPC274(orf name)|uniprotkb:UNQ2432/PRO4992(orf name) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085316|imex:IM-27807-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009923.1|refseq:NP_001009924.1|refseq:NP_001009925.1|refseq:NP_054864.3|refseq:NP_001317913.1|refseq:NP_001317914.1|refseq:NP_001317915.1|refseq:XP_016883325.1|ensembl:ENSG00000089063(gene)|ensembl:ENST00000202834(transcript)|ensembl:ENST00000379277(transcript)|ensembl:ENST00000379279(transcript)|ensembl:ENST00000379283(transcript)|ensembl:ENST00000379286(transcript)|ensembl:ENST00000379299(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0055037"(recycling endosome)|interpro:IPR008590(Protein of unknown function DUF872, eukaryotic)|interpro:IPR044234 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:n9vIcFyub2Fl+lSnmvcQ1DrA7PE9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:gpm5/dQyS2Cqrs+nWnvaZ2cECZk false sufficient binding region:6-120|nub:?-? cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96B49 uniprotkb:Q5T9L3-1 intact:EBI-10826510|uniprotkb:B2DG15|uniprotkb:Q9UH52|ensembl:ENSP00000381856|ensembl:ENSP00000381859 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:tom6_human(display_long)|uniprotkb:TOMM6(gene name)|psi-mi:TOMM6(display_short)|uniprotkb:Overexpressed breast tumor protein(gene name synonym)|uniprotkb:Translocase of outer membrane 6 kDa subunit homolog(gene name synonym)|uniprotkb:OBTP(gene name synonym)|uniprotkb:TOM6(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085326|imex:IM-27807-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001127965.1|ensembl:ENSG00000214736(gene)|ensembl:ENST00000398881(transcript)|ensembl:ENST00000398884(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0015031"(protein transport)|interpro:IPR029182|mint:Q96B49|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:j3q/LBZ1XHboUAcHka+T8XtNsIM9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:2HpZWIJLIRcewUBXu3L95GSqGhU false nub:?-? cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NYZ1 uniprotkb:Q5T9L3-1 intact:EBI-11343401|uniprotkb:A8K448|uniprotkb:Q9Y3E6|uniprotkb:Q96HK5|ensembl:ENSP00000305654 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:tv23b_human(display_long)|uniprotkb:TVP23B(gene name)|psi-mi:TVP23B(display_short)|uniprotkb:FAM18B(gene name synonym)|uniprotkb:FAM18B1(gene name synonym)|uniprotkb:CGI-148(orf name)|uniprotkb:NPD008(orf name) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085334|imex:IM-27807-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001303848.1|refseq:NP_001303849.1|refseq:NP_001303850.1|refseq:NP_001303851.1|refseq:NP_001303852.1|refseq:NP_001303853.1|refseq:NP_057162.4|ensembl:ENSG00000171928(gene)|ensembl:ENST00000307767(transcript)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|interpro:IPR008564(Protein of unknown function DUF846, eukaryotic) ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:gxyJHSx9RYFnyhZFDzRLW8QwzmU9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:oWGHNBW5HRehlqkiWYfLFY3zi0s false sufficient binding region:34-142|nub:?-? cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96EC8 uniprotkb:Q5T9L3-1 intact:EBI-751210|uniprotkb:Q5JP08|uniprotkb:B4E1U7|uniprotkb:G5E997|ensembl:ENSP00000417573 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:yipf6_human(display_long)|uniprotkb:YIP1 family member 6(gene name synonym)|uniprotkb:YIPF6(gene name)|psi-mi:YIPF6(display_short) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085344|imex:IM-27807-109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776195.2|refseq:NP_001182143.1|ensembl:ENSG00000181704(gene)|ensembl:ENST00000462683(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0060576"(intestinal epithelial cell development)|interpro:IPR006977(Yip1 domain)|mint:Q96EC8|reactome:R-HSA-432722 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:mfHkmdPyX5lK/euzg8v1Ydikf5w9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:jNXR4N5NFUw6j0AafppGgylpsk0 false sufficient binding region:1-236|nub:?-? cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5T742 uniprotkb:Q5T9L3-1 intact:EBI-20865573|uniprotkb:A1L424|uniprotkb:Q96NM5 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:zfas1_human(display_long)|uniprotkb:ZNF22-AS1(gene name)|psi-mi:ZNF22-AS1(display_short)|uniprotkb:C10orf25(gene name synonym)|uniprotkb:ZNF22 antisense RNA 1(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085440|imex:IM-27807-91 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005576"(extracellular region)|refseq:NP_001034469.2|refseq:XP_016871384.1 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:LflkbwoJqv8ftu6WTtkY/jeG/h49606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:ZBhh6oPJHs1gJ/OUjjZwqCcggbs false nub:n-n cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O94777 uniprotkb:Q5T9L3-1 intact:EBI-9097061|uniprotkb:Q5XKK9|uniprotkb:Q6FGH3|ensembl:ENSP00000322181 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:dpm2_human(display_long)|uniprotkb:DPM2(gene name)|psi-mi:DPM2(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 2(gene name synonym)|uniprotkb:My026(orf name) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085785|imex:IM-27807-95 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003854.1|ensembl:ENSG00000136908(gene)|ensembl:ENST00000314392(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR009914(Dolichol phosphate-mannose biosynthesis regulatory)|reactome:R-HSA-162699|reactome:R-HSA-162710|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:b1kR+UX6Sfr1TcOpQ0D4M3+xy8M9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:AzfKbRabr252z4duhzVhe+VXP8U false nub:n-n cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7Z7B1 uniprotkb:Q5T9L3-1 intact:EBI-21505660|ensembl:ENSP00000480021|ensembl:ENSP00000481144|ensembl:ENSP00000482202|ensembl:ENSP00000488033|uniprotkb:Q8N9G3 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:pigw_human(display_long)|uniprotkb:PIGW(gene name)|psi-mi:PIGW(display_short) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22086112|imex:IM-27807-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000275600(gene)|ensembl:ENSG00000277161(gene)|ensembl:ENST00000614443(transcript)|ensembl:ENST00000616581(transcript)|ensembl:ENST00000620233(transcript)|ensembl:ENST00000631508(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006505"(GPI anchor metabolic process)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016254"(preassembly of GPI anchor in ER membrane)|go:"GO:0032216"(glucosaminyl-phosphatidylinositol O-acyltransferase activity)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR009447(GWT1)|reactome:R-HSA-162710|refseq:NP_001333683.1|refseq:NP_001333684.1|refseq:NP_848612.2 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:1AGBg5TjHW5YNjN7IeJR7/7Foj49606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:hhMvaOhvtTkjjzsXQ88jdePPdsA false nub:?-?|sufficient binding region:417-504 cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UHD1 uniprotkb:Q5T9L3-1 intact:EBI-2550959|ensembl:ENSP00000319255|ensembl:ENSP00000496744|uniprotkb:Q9H3D6|uniprotkb:Q8WVL9|uniprotkb:B2R6P8|uniprotkb:Q6IN49 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:chrd1_human(display_long)|uniprotkb:CHP1(gene name synonym)|uniprotkb:CHORD domain-containing protein 1(gene name synonym)|uniprotkb:CHORDC1(gene name)|psi-mi:CHORDC1(display_short)|uniprotkb:Protein morgana(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085401|imex:IM-27807-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000110172(gene)|ensembl:ENSG00000285023(gene)|ensembl:ENST00000320585(transcript)|ensembl:ENST00000646618(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0043531"(ADP binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:2000299"(negative regulation of Rho-dependent protein serine/threonine kinase activity)|interpro:IPR007051(CHORD)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|rcsb pdb:2YRT|go:"GO:1900034"(regulation of cellular response to heat)|refseq:NP_001137545.1|refseq:NP_036256.2 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:hlLw4jieLbD+CRQ/Nav7CR+YlUY9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:sKP87bTkxP1qS4cvL3gHwmfw9i8 false - sufficient binding region:493-541 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O96011 uniprotkb:Q5T9L3-1 intact:EBI-594824|uniprotkb:Q96ET2|uniprotkb:B3KN85|uniprotkb:B4DXH9|ensembl:ENSP00000358312 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:px11b_human(display_long)|uniprotkb:Peroxisomal biogenesis factor 11B(gene name synonym)|uniprotkb:Protein PEX11 homolog beta(gene name synonym)|uniprotkb:PEX11B(gene name)|psi-mi:PEX11B(display_short)|uniprotkb:Peroxin-11B(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085395|imex:IM-27807-85 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003837.1|refseq:NP_001171724.1|ensembl:ENSG00000131779(gene)|ensembl:ENST00000369306(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044375"(regulation of peroxisome size)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-HSA-9603798 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:5/6FYSwT/s0zO+x+5vM73A1sCsA9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:+lz3tCKAr6MQWPndrbOTQRDd6vc false - sufficient binding region:493-541 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P21796 uniprotkb:Q5T9L3-1 intact:EBI-354158|uniprotkb:Q5FVE7|uniprotkb:Q9UIQ5|uniprotkb:Q9UPL0|uniprotkb:B3KVK4|uniprotkb:D3DQ93|ensembl:ENSP00000265333|ensembl:ENSP00000378484|ensembl:ENSP00000378487 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:vdac1_human(display_long)|uniprotkb:VDAC1(gene name)|psi-mi:VDAC1(display_short)|uniprotkb:VDAC(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 1(gene name synonym)|uniprotkb:Plasmalemmal porin(gene name synonym)|uniprotkb:Porin 31HL(gene name synonym)|uniprotkb:Porin 31HM(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085387|imex:IM-27807-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003365.1|refseq:XP_005272132.1|refseq:XP_016865310.1|refseq:XP_016865311.1|refseq:XP_016865312.1|dip:DIP-32862N|ensembl:ENSG00000213585(gene)|ensembl:ENST00000265333(transcript)|ensembl:ENST00000395044(transcript)|ensembl:ENST00000395047(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006820"(anion transport)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097001"(ceramide binding)|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030270|mint:P21796|rcsb pdb:2JK4|rcsb pdb:2K4T|rcsb pdb:5JDP|rcsb pdb:5XDN|rcsb pdb:5XDO|rcsb pdb:6G6U|rcsb pdb:6G73|rcsb pdb:6TIQ|rcsb pdb:6TIR|reactome:R-HSA-1268020|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-70268|reactome:R-HSA-8949215 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:8Fqe6Ga3NmwwuICa4L45ga2i1nk9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:ho6hujzLUrKp8KWZr0ljDAY/h+U false sufficient binding region:34-95 sufficient binding region:493-541 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8NEZ4-3 uniprotkb:Q5T9L3-1 intact:EBI-22081190|ensembl:ENSP00000507485 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:q8nez4-3(display_long)|uniprotkb:KMT2C(gene name)|psi-mi:KMT2C(display_short)|uniprotkb:HALR(gene name synonym)|uniprotkb:KIAA1506(gene name synonym)|uniprotkb:MLL3(gene name synonym)|uniprotkb:Homologous to ALR protein(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 3(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085371|imex:IM-27807-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000682283(transcript)|ensembl:ENSG00000055609(gene)|intact:EBI-1042997(isoform-parent) ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - isoform-comment:No experimental confirmation available. - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:U4goNcqmvCxXbCH+sYv4L9AWzoM9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:YhHIe/6FBW6hkKZg2ybuRep/9zk false sufficient binding region:4926-4964 sufficient binding region:493-541 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BPX7-2 uniprotkb:Q5T9L3-1 intact:EBI-22081070|ensembl:ENSP00000413029 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:q9bpx7-2(display_long)|uniprotkb:C7orf25(gene name)|psi-mi:C7orf25(display_short) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085379|imex:IM-27807-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000136197(gene)|ensembl:ENST00000447342(transcript)|intact:EBI-718586(isoform-parent) ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:CoMr/aWYoDgwChC91ZNy/Uio/0M9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:RfE5R2OaUpuKK0Hzi1k4jbfVncw false sufficient binding region:298-436 sufficient binding region:493-541 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7Z7B1 uniprotkb:Q5T9L3-1 intact:EBI-21505660|ensembl:ENSP00000480021|ensembl:ENSP00000481144|ensembl:ENSP00000482202|ensembl:ENSP00000488033|uniprotkb:Q8N9G3 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:pigw_human(display_long)|uniprotkb:PIGW(gene name)|psi-mi:PIGW(display_short) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085407|imex:IM-27807-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000275600(gene)|ensembl:ENSG00000277161(gene)|ensembl:ENST00000614443(transcript)|ensembl:ENST00000616581(transcript)|ensembl:ENST00000620233(transcript)|ensembl:ENST00000631508(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006505"(GPI anchor metabolic process)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016254"(preassembly of GPI anchor in ER membrane)|go:"GO:0032216"(glucosaminyl-phosphatidylinositol O-acyltransferase activity)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR009447(GWT1)|reactome:R-HSA-162710|refseq:NP_001333683.1|refseq:NP_001333684.1|refseq:NP_848612.2 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:1AGBg5TjHW5YNjN7IeJR7/7Foj49606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:hhMvaOhvtTkjjzsXQ88jdePPdsA false sufficient binding region:417-504 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q01518 uniprotkb:Q5T9L3-1 intact:EBI-2808398|ensembl:ENSP00000361878|ensembl:ENSP00000361883|ensembl:ENSP00000361891|uniprotkb:Q6I9U6|uniprotkb:Q5T0S2|uniprotkb:Q53HR7|uniprotkb:Q5T0S1 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:cap1_human(display_long)|uniprotkb:CAP1(gene name)|psi-mi:CAP1(display_short)|uniprotkb:CAP(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085422|imex:IM-27807-89 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131236(gene)|ensembl:ENST00000372792(transcript)|ensembl:ENST00000372797(transcript)|ensembl:ENST00000372805(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028415|interpro:IPR028417|go:"GO:0001667"(ameboidal-type cell migration)|interpro:IPR036222|interpro:IPR036223|mint:Q01518|rcsb pdb:1K8F|reactome:R-HSA-114608|reactome:R-HSA-428890|reactome:R-HSA-6798695|refseq:XP_011538811.1|refseq:XP_011538812.1|refseq:XP_011538813.1|refseq:XP_011538814.1|refseq:XP_011538815.1|refseq:XP_011538816.1|refseq:XP_011538817.1|refseq:NP_001099000.1|refseq:NP_006358.1|refseq:XP_016855556.1|refseq:XP_016855557.1|refseq:XP_016855558.1|refseq:XP_016855559.1|refseq:XP_016855560.1|refseq:XP_016855561.1|refseq:XP_005270425.1|dip:DIP-62063N ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - crc64:7789D1FAC0D1AB7B - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:BXrQm0u+e0xVOl2b+A18GrZy5Eg9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:+OXz5YPd6N3Zwbw7o9Hnn1MwYzU false sufficient binding region:411-475 sufficient binding region:493-541 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P55087 uniprotkb:Q5T9L3-1 intact:EBI-10104898|uniprotkb:P78564|ensembl:ENSP00000372654|ensembl:ENSP00000500720 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:aqp4_human(display_long)|uniprotkb:AQP4(gene name)|psi-mi:AQP4(display_short)|uniprotkb:Mercurial-insensitive water channel(gene name synonym)|uniprotkb:WCH4(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085430|imex:IM-27807-125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001641.1|refseq:NP_004019.1|ensembl:ENSG00000171885(gene)|ensembl:ENST00000383168(transcript)|ensembl:ENST00000672188(transcript)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006833"(water transport)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0010008"(endosome membrane)|go:"GO:0015250"(water channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030104"(water homeostasis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097450"(astrocyte end-foot)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|interpro:IPR034294|rcsb pdb:3GD8|reactome:R-HSA-432040|reactome:R-HSA-432047|dip:DIP-48842N ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:emloJNSTB0zSwtP91cSKBBr4PA89606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:g8T9s/Y6VKE2rvXk6G339NmfOQs false sufficient binding region:1-184 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5T742 uniprotkb:Q5T9L3-1 intact:EBI-20865573|uniprotkb:A1L424|uniprotkb:Q96NM5 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:zfas1_human(display_long)|uniprotkb:ZNF22-AS1(gene name)|psi-mi:ZNF22-AS1(display_short)|uniprotkb:C10orf25(gene name synonym)|uniprotkb:ZNF22 antisense RNA 1(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085450|imex:IM-27807-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005576"(extracellular region)|refseq:NP_001034469.2|refseq:XP_016871384.1 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:LflkbwoJqv8ftu6WTtkY/jeG/h49606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:ZBhh6oPJHs1gJ/OUjjZwqCcggbs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96B45 uniprotkb:Q5T9L3-1 intact:EBI-6151489|uniprotkb:C9K0X3|uniprotkb:B3KUW4|uniprotkb:B2R488|ensembl:ENSP00000342331|ensembl:ENSP00000358899 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:borc7_human(display_long)|uniprotkb:BORCS7(gene name)|psi-mi:BORCS7(display_short)|uniprotkb:C10orf32(gene name synonym)|uniprotkb:Diaskedin(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085458|imex:IM-27807-111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129672.1|refseq:NP_653192.2|ensembl:ENSG00000166275(gene)|ensembl:ENST00000339834(transcript)|ensembl:ENST00000369883(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0099078"(BORC complex)|interpro:IPR032143 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:nWmtuEe/BAme4MMt55fvFjyGNss9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:eHqiM9qL23NEYmOVSw7rnqN4aRw false sufficient binding region:1-77 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NPA0 uniprotkb:Q5T9L3-1 intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085509|imex:IM-27807-113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:E4SLLC2dFVPKkpGiAGNlYfzuPp0 false sufficient binding region:37-242 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5T9L3-1 uniprotkb:Q9Y6G1 intact:EBI-22114623|ensembl:ENSP00000262348 intact:EBI-2800360|uniprotkb:B2R552|ensembl:ENSP00000211314 psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:tm14a_human(display_long)|uniprotkb:C6orf73(gene name synonym)|uniprotkb:PTD011(orf name)|uniprotkb:TMEM14A(gene name)|psi-mi:TMEM14A(display_short) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085519|imex:IM-27807-115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) ensembl:ENST00000211314(transcript)|refseq:NP_054770.1|ensembl:ENSG00000096092(gene)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|interpro:IPR005349(Protein of unknown function UPF0136, Transmembrane)|interpro:IPR044890|mint:Q9Y6G1|rcsb pdb:2LOO|rcsb pdb:2LOP|go:"GO:0005789"(endoplasmic reticulum membrane) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rogid:nrvzpoAjkgMJIDiqVIVa5b3jLsQ9606 rigid:boKV7iPAWf+PB+piwbDNFPA8Mvg false - sufficient binding region:1-99 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H6X4 uniprotkb:Q5T9L3-1 intact:EBI-22084643|uniprotkb:Q08AK4|uniprotkb:Q6PJN3|ensembl:ENSP00000312615 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:tm134_human(display_long)|uniprotkb:TMEM134(gene name)|psi-mi:TMEM134(display_short) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085706|imex:IM-27807-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001072118.1|refseq:NP_001072119.1|refseq:NP_079400.1|ensembl:ENSG00000172663(gene)|ensembl:ENST00000308022(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR008590(Protein of unknown function DUF872, eukaryotic)|interpro:IPR039714 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:lutWi4WCwdkEPwUXGiONGVN/xvY9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:Hc4jmXCgOST8sj0GjNZTGHYOVAo false sufficient binding region:1-165 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NX00 uniprotkb:Q5T9L3-1 intact:EBI-2514588|ensembl:ENSP00000253047|uniprotkb:Q9BU41 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:tm160_human(display_long)|uniprotkb:TMEM160(gene name)|psi-mi:TMEM160(display_short) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085716|imex:IM-27807-93 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130748(gene)|ensembl:ENST00000253047(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR026801|refseq:NP_060324.1 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:5PuVgGSb9lQAD5/1RS6csGdai0Q9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:kD+ZPFFOoMRy8zJLcW1rRQTeYeE false sufficient binding region:17-187 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96A57 uniprotkb:Q5T9L3-1 intact:EBI-723971|uniprotkb:D3DVZ9|uniprotkb:Q0VGC8|uniprotkb:Q5TDS5|uniprotkb:Q96ES2|uniprotkb:Q9P0A7|uniprotkb:B2RDM8|ensembl:ENSP00000202834|ensembl:ENSP00000368579|ensembl:ENSP00000368581|ensembl:ENSP00000368585|ensembl:ENSP00000368588|ensembl:ENSP00000368601 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:tm230_human(display_long)|uniprotkb:TMEM230(gene name)|psi-mi:TMEM230(display_short)|uniprotkb:C20orf30(gene name synonym)|uniprotkb:HSPC274(orf name)|uniprotkb:UNQ2432/PRO4992(orf name) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085726|imex:IM-27807-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009923.1|refseq:NP_001009924.1|refseq:NP_001009925.1|refseq:NP_054864.3|refseq:NP_001317913.1|refseq:NP_001317914.1|refseq:NP_001317915.1|refseq:XP_016883325.1|ensembl:ENSG00000089063(gene)|ensembl:ENST00000202834(transcript)|ensembl:ENST00000379277(transcript)|ensembl:ENST00000379279(transcript)|ensembl:ENST00000379283(transcript)|ensembl:ENST00000379286(transcript)|ensembl:ENST00000379299(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0055037"(recycling endosome)|interpro:IPR008590(Protein of unknown function DUF872, eukaryotic)|interpro:IPR044234 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:n9vIcFyub2Fl+lSnmvcQ1DrA7PE9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:gpm5/dQyS2Cqrs+nWnvaZ2cECZk false sufficient binding region:6-120 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P48436 uniprotkb:Q5T9L3-1 intact:EBI-3920028|ensembl:ENSP00000245479|uniprotkb:Q53Y80 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:sox9_human(display_long)|uniprotkb:SOX9(gene name)|psi-mi:SOX9(display_short) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085736|imex:IM-27807-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000125398(gene)|ensembl:ENST00000245479(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001503"(ossification)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001708"(cell fate specification)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001942"(hair follicle development)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002683"(negative regulation of immune system process)|go:"GO:0003170"(heart valve development)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003188"(heart valve formation)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003413"(chondrocyte differentiation involved in endochondral bone morphogenesis)|go:"GO:0003415"(chondrocyte hypertrophy)|go:"GO:0003430"(growth plate cartilage chondrocyte growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0014032"(neural crest cell development)|go:"GO:0014036"(neural crest cell fate specification)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0030850"(prostate gland development)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0030903"(notochord development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0035622"(intrahepatic bile duct development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046322"(negative regulation of fatty acid oxidation)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051216"(cartilage development)|go:"GO:0060008"(Sertoli cell differentiation)|go:"GO:0060009"(Sertoli cell development)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060174"(limb bud formation)|go:"GO:0060221"(retinal rod cell differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060517"(epithelial cell proliferation involved in prostatic bud elongation)|go:"GO:0060532"(bronchus cartilage development)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0060784"(regulation of cell proliferation involved in tissue homeostasis)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0061046"(regulation of branching involved in lung morphogenesis)|go:"GO:0061138"(morphogenesis of a branching epithelium)|go:"GO:0061145"(lung smooth muscle development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070384"(Harderian gland development)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071504"(cellular response to heparin)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0072034"(renal vesicle induction)|go:"GO:0072190"(ureter urothelium development)|go:"GO:0072193"(ureter smooth muscle cell differentiation)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0072289"(metanephric nephron tubule formation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090184"(positive regulation of kidney development)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:0097065"(anterior head development)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000020"(positive regulation of male gonad development)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|go:"GO:2000741"(positive regulation of mesenchymal stem cell differentiation)|go:"GO:2000794"(regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:2001054"(negative regulation of mesenchymal cell apoptotic process)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022151|interpro:IPR029548|interpro:IPR036910|rcsb pdb:1S9M|rcsb pdb:1SX9|rcsb pdb:4EUW|reactome:R-HSA-3769402|reactome:R-HSA-8878166|reactome:R-HSA-9690406|refseq:NP_000337.1|dip:DIP-61319N ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:9tMOPJUNgC89D1SdrN0b4yCXRUk9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:dpRl4yucgoJmiF1fEB4/s5LHZ40 false sufficient binding region:381-458 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P08962 uniprotkb:Q5T9L3-1 intact:EBI-762053|uniprotkb:Q5TZP3|uniprotkb:Q9UCG6|uniprotkb:Q8N6Z9|uniprotkb:F8VZE2|ensembl:ENSP00000257857|ensembl:ENSP00000393502|ensembl:ENSP00000447730|ensembl:ENSP00000449337 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:cd63_human(display_long)|uniprotkb:Melanoma-associated antigen ME491(gene name synonym)|uniprotkb:Ocular melanoma-associated antigen(gene name synonym)|uniprotkb:OMA81H(gene name synonym)|uniprotkb:Granulophysin(gene name synonym)|uniprotkb:Tetraspanin-30(gene name synonym)|uniprotkb:Lysosomal-associated membrane protein 3(gene name synonym)|uniprotkb:CD63(gene name)|psi-mi:CD63(display_short)|uniprotkb:MLA1(gene name synonym)|uniprotkb:TSPAN30(gene name synonym)|uniprotkb:Lysosome integral membrane protein 1(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085746|imex:IM-27807-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001771.1|refseq:NP_001244330.1|refseq:NP_001244318.1|refseq:NP_001244319.1|refseq:NP_001244320.1|refseq:NP_001244329.1|refseq:NP_001254627.1|refseq:NP_001244321.1|ensembl:ENSG00000135404(gene)|ensembl:ENST00000257857(transcript)|go:"GO:1900746"(regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|interpro:IPR042028|mint:P08962|reactome:R-HSA-114608|reactome:R-HSA-6798695|go:"GO:0097487"(multivesicular body, internal vesicle)|ensembl:ENST00000420846(transcript)|ensembl:ENST00000549117(transcript)|ensembl:ENST00000552692(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016477"(cell migration)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048757"(pigment granule maturation)|go:"GO:0070062"(extracellular exosome) ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:stCGi5kkTMIdO84qSwjmjpUwwvs9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:ffJ6ujWLYAtlMzFrcBw/PmevhoI false sufficient binding region:123-197 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9P003 uniprotkb:Q5T9L3-1 intact:EBI-1044341|ensembl:ENSP00000420443|uniprotkb:Q9H0X8|uniprotkb:A8K1Q8|uniprotkb:B2R553 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:cnih4_human(display_long)|uniprotkb:CNIH4(gene name)|psi-mi:CNIH4(display_short)|uniprotkb:Cornichon family AMPA receptor auxiliary protein 4(gene name synonym)|uniprotkb:HSPC163(orf name) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085756|imex:IM-27807-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000465271(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031730"(CCR5 chemokine receptor binding)|interpro:IPR003377(Cornichon)|ensembl:ENSG00000143771(gene)|refseq:NP_054903.1|refseq:NP_001264126.1 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:vKqBlBp/B2XQikBgv7RZH8IymEo9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:9bgmzDNuSacEjkXsoJDGkDKyCVM false sufficient binding region:1-138 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q01959 uniprotkb:Q5T9L3-1 intact:EBI-6661445|ensembl:ENSP00000270349|ensembl:ENSP00000479597|uniprotkb:A2RUN4|uniprotkb:Q14996 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:sc6a3_human(display_long)|uniprotkb:SLC6A3(gene name)|psi-mi:SLC6A3(display_short)|uniprotkb:DAT1(gene name synonym)|uniprotkb:Solute carrier family 6 member 3(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085775|imex:IM-27807-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0007626"(locomotory behavior)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0016600"(flotillin complex)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0010039"(response to iron ion)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|mint:Q01959|reactome:R-HSA-379401|reactome:R-HSA-442660|reactome:R-HSA-5619081|reactome:R-HSA-5660724|ensembl:ENSG00000142319(gene)|ensembl:ENSG00000276996(gene)|ensembl:ENST00000270349(transcript)|ensembl:ENST00000621716(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|refseq:NP_001035.1|dip:DIP-41827N ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:mQKSGpeovNv4Sg8T2E3A8rVB2aY9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:Yl3c2Gib5SvIg1+yr6+7V8NzwnI false sufficient binding region:1-343 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O94777 uniprotkb:Q5T9L3-1 intact:EBI-9097061|uniprotkb:Q5XKK9|uniprotkb:Q6FGH3|ensembl:ENSP00000322181 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:dpm2_human(display_long)|uniprotkb:DPM2(gene name)|psi-mi:DPM2(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 2(gene name synonym)|uniprotkb:My026(orf name) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085795|imex:IM-27807-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003854.1|ensembl:ENSG00000136908(gene)|ensembl:ENST00000314392(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR009914(Dolichol phosphate-mannose biosynthesis regulatory)|reactome:R-HSA-162699|reactome:R-HSA-162710|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:b1kR+UX6Sfr1TcOpQ0D4M3+xy8M9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:AzfKbRabr252z4duhzVhe+VXP8U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15125 uniprotkb:Q5T9L3-1 intact:EBI-3915253|uniprotkb:Q6IBI9|uniprotkb:Q6FGL3|ensembl:ENSP00000417052 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:ebp_human(display_long)|uniprotkb:EBP(gene name)|psi-mi:EBP(display_short)|uniprotkb:Cholestenol Delta-isomerase(gene name synonym)|uniprotkb:"Delta(8)-Delta(7) sterol isomerase"(gene name synonym)|uniprotkb:Emopamil-binding protein(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22085806|imex:IM-27807-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006570.1|ensembl:ENSG00000147155(gene)|ensembl:ENST00000495186(transcript)|go:"GO:0000247"(C-8 sterol isomerase activity)|go:"GO:0001501"(skeletal system development)|go:"GO:0004769"(steroid delta-isomerase activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033489"(cholesterol biosynthetic process via desmosterol)|go:"GO:0033490"(cholesterol biosynthetic process via lathosterol)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0047750"(cholestenol delta-isomerase activity)|interpro:IPR007905(Emopamil-binding)|interpro:IPR033118|rcsb pdb:6OHT|rcsb pdb:6OHU|reactome:R-HSA-6807047|reactome:R-HSA-6807062 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:7XfeeD/twqYll0Hv4YuJUbmAVJ09606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:pmvcuLGrR4/ZDQASXWFAncGKbnI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5T9L3-1 uniprotkb:Q9UN67 intact:EBI-22114623|ensembl:ENSP00000262348 intact:EBI-6308942|ensembl:ENSP00000239446|uniprotkb:Q96T99 psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:pcdba_human(display_long)|uniprotkb:PCDHB10(gene name)|psi-mi:PCDHB10(display_short)|uniprotkb:UNQ1906/PRO4352(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22086013|imex:IM-27807-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) ensembl:ENSG00000120324(gene)|ensembl:ENST00000239446(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0045202"(synapse)|interpro:IPR002126(Cadherin)|interpro:IPR013164(Cadherin, N-terminal)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR032455|refseq:NP_061753.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rogid:eDBO6rRJdTj1TzDUyXxX+iDJywo9606 rigid:MfFvYxgXKRlP0ol+v1EU18ScP/E false - sufficient binding region:682-800 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96B49 uniprotkb:Q5T9L3-1 intact:EBI-10826510|uniprotkb:B2DG15|uniprotkb:Q9UH52|ensembl:ENSP00000381856|ensembl:ENSP00000381859 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:tom6_human(display_long)|uniprotkb:TOMM6(gene name)|psi-mi:TOMM6(display_short)|uniprotkb:Overexpressed breast tumor protein(gene name synonym)|uniprotkb:Translocase of outer membrane 6 kDa subunit homolog(gene name synonym)|uniprotkb:OBTP(gene name synonym)|uniprotkb:TOM6(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22086124|imex:IM-27807-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001127965.1|ensembl:ENSG00000214736(gene)|ensembl:ENST00000398881(transcript)|ensembl:ENST00000398884(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0015031"(protein transport)|interpro:IPR029182|mint:Q96B49|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:j3q/LBZ1XHboUAcHka+T8XtNsIM9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:2HpZWIJLIRcewUBXu3L95GSqGhU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NYZ1 uniprotkb:Q5T9L3-1 intact:EBI-11343401|uniprotkb:A8K448|uniprotkb:Q9Y3E6|uniprotkb:Q96HK5|ensembl:ENSP00000305654 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:tv23b_human(display_long)|uniprotkb:TVP23B(gene name)|psi-mi:TVP23B(display_short)|uniprotkb:FAM18B(gene name synonym)|uniprotkb:FAM18B1(gene name synonym)|uniprotkb:CGI-148(orf name)|uniprotkb:NPD008(orf name) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22086132|imex:IM-27807-117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001303848.1|refseq:NP_001303849.1|refseq:NP_001303850.1|refseq:NP_001303851.1|refseq:NP_001303852.1|refseq:NP_001303853.1|refseq:NP_057162.4|ensembl:ENSG00000171928(gene)|ensembl:ENST00000307767(transcript)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|interpro:IPR008564(Protein of unknown function DUF846, eukaryotic) ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:gxyJHSx9RYFnyhZFDzRLW8QwzmU9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:oWGHNBW5HRehlqkiWYfLFY3zi0s false sufficient binding region:34-142 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96EC8 uniprotkb:Q5T9L3-1 intact:EBI-751210|uniprotkb:Q5JP08|uniprotkb:B4E1U7|uniprotkb:G5E997|ensembl:ENSP00000417573 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:yipf6_human(display_long)|uniprotkb:YIP1 family member 6(gene name synonym)|uniprotkb:YIPF6(gene name)|psi-mi:YIPF6(display_short) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22086142|imex:IM-27807-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776195.2|refseq:NP_001182143.1|ensembl:ENSG00000181704(gene)|ensembl:ENST00000462683(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0060576"(intestinal epithelial cell development)|interpro:IPR006977(Yip1 domain)|mint:Q96EC8|reactome:R-HSA-432722 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:mfHkmdPyX5lK/euzg8v1Ydikf5w9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:jNXR4N5NFUw6j0AafppGgylpsk0 false sufficient binding region:1-236 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96D05 uniprotkb:Q5T9L3-1 intact:EBI-2548784|ensembl:ENSP00000362376 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:f241b_human(display_long)|uniprotkb:FAM241B(gene name)|psi-mi:FAM241B(display_short)|uniprotkb:C10orf35(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22086154|imex:IM-27807-127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171224(gene)|ensembl:ENST00000373279(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR027953|mint:Q96D05|refseq:XP_011537757.1|refseq:NP_660349.1|refseq:XP_005269663.1|refseq:XP_005269665.1|refseq:XP_016871325.1 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:2Iylns4G5knUSJCXAPnLUE9laUU9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:srpjoKZHsJUrcPQhwuuwBq+d0Aw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BQI5 uniprotkb:Q5T9L3-1 intact:EBI-2690801|uniprotkb:Q6MZY6|uniprotkb:A6NLD1|uniprotkb:Q5VYE2|uniprotkb:A6NL81|uniprotkb:Q8IWC2|uniprotkb:Q68D76|uniprotkb:Q4LE32|uniprotkb:Q5VYE4|uniprotkb:Q5VYE3|ensembl:ENSP00000360076 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:sgip1_human(display_long)|uniprotkb:Endophilin-3-interacting protein(gene name synonym)|uniprotkb:SGIP1(gene name)|psi-mi:SGIP1(display_short) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0018"(two hybrid) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22086818|imex:IM-27807-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006711037.1|refseq:NP_001295132.1|refseq:XP_016858000.1|refseq:XP_016858001.1|refseq:XP_016858023.1|refseq:XP_016858024.1|refseq:NP_115667.2|refseq:XP_005271321.1|refseq:XP_005271327.1|ensembl:ENSG00000118473(gene)|ensembl:ENST00000371037(transcript)|go:"GO:0002021"(response to dietary excess)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0008017"(microtubule binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097009"(energy homeostasis)|go:"GO:2000253"(positive regulation of feeding behavior)|interpro:IPR018808|interpro:IPR028565|interpro:IPR036168|interpro:IPR037984|mint:Q9BQI5|rcsb pdb:5AWR|rcsb pdb:5AWS|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:6A9Y|reactome:R-HSA-8856825|reactome:R-HSA-8856828 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/10/08 2019/10/21 rogid:zFAutzD0AvL0d3TY1e1+TCO1vO09606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:frqjevxl/Z11oRqmwVG+dEEX3do false - sufficient binding region:493-541 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96D05 uniprotkb:Q5T9L3 intact:EBI-2548784|ensembl:ENSP00000362376 intact:EBI-2868748|uniprotkb:Q8NC43|uniprotkb:Q7Z2Z9|uniprotkb:B2RNT2|intact:EBI-11046890|uniprotkb:Q5JRS7|ensembl:ENSP00000262348 psi-mi:f241b_human(display_long)|uniprotkb:FAM241B(gene name)|psi-mi:FAM241B(display_short)|uniprotkb:C10orf35(gene name synonym) psi-mi:wls_human(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22086784|imex:IM-27807-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171224(gene)|ensembl:ENST00000373279(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR027953|mint:Q96D05|refseq:XP_011537757.1|refseq:NP_660349.1|refseq:XP_005269663.1|refseq:XP_005269665.1|refseq:XP_016871325.1 refseq:NP_001180263.1|refseq:NP_001002292.3|refseq:NP_079187.3|ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061355"(Wnt protein secretion)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR009551(Protein of unknown function DUF1171)|mint:Q5T9L3|rcsb pdb:7KC4|reactome:R-HSA-3238698|go:"GO:0070062"(extracellular exosome) - - - figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/10/08 2019/10/15 rogid:2Iylns4G5knUSJCXAPnLUE9laUU9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:srpjoKZHsJUrcPQhwuuwBq+d0Aw false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q15125 uniprotkb:Q5T9L3 intact:EBI-3915253|uniprotkb:Q6IBI9|uniprotkb:Q6FGL3|ensembl:ENSP00000417052 intact:EBI-2868748|uniprotkb:Q8NC43|uniprotkb:Q7Z2Z9|uniprotkb:B2RNT2|intact:EBI-11046890|uniprotkb:Q5JRS7|ensembl:ENSP00000262348 psi-mi:ebp_human(display_long)|uniprotkb:EBP(gene name)|psi-mi:EBP(display_short)|uniprotkb:Cholestenol Delta-isomerase(gene name synonym)|uniprotkb:"Delta(8)-Delta(7) sterol isomerase"(gene name synonym)|uniprotkb:Emopamil-binding protein(gene name synonym) psi-mi:wls_human(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22086792|imex:IM-27807-119 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006570.1|ensembl:ENSG00000147155(gene)|ensembl:ENST00000495186(transcript)|go:"GO:0000247"(C-8 sterol isomerase activity)|go:"GO:0001501"(skeletal system development)|go:"GO:0004769"(steroid delta-isomerase activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033489"(cholesterol biosynthetic process via desmosterol)|go:"GO:0033490"(cholesterol biosynthetic process via lathosterol)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0047750"(cholestenol delta-isomerase activity)|interpro:IPR007905(Emopamil-binding)|interpro:IPR033118|rcsb pdb:6OHT|rcsb pdb:6OHU|reactome:R-HSA-6807047|reactome:R-HSA-6807062 refseq:NP_001180263.1|refseq:NP_001002292.3|refseq:NP_079187.3|ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061355"(Wnt protein secretion)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR009551(Protein of unknown function DUF1171)|mint:Q5T9L3|rcsb pdb:7KC4|reactome:R-HSA-3238698|go:"GO:0070062"(extracellular exosome) - - - figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/10/08 2019/10/15 rogid:7XfeeD/twqYll0Hv4YuJUbmAVJ09606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:pmvcuLGrR4/ZDQASXWFAncGKbnI false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01959 uniprotkb:Q5T9L3 intact:EBI-6661445|ensembl:ENSP00000270349|ensembl:ENSP00000479597|uniprotkb:A2RUN4|uniprotkb:Q14996 intact:EBI-2868748|uniprotkb:Q8NC43|uniprotkb:Q7Z2Z9|uniprotkb:B2RNT2|intact:EBI-11046890|uniprotkb:Q5JRS7|ensembl:ENSP00000262348 psi-mi:sc6a3_human(display_long)|uniprotkb:SLC6A3(gene name)|psi-mi:SLC6A3(display_short)|uniprotkb:DAT1(gene name synonym)|uniprotkb:Solute carrier family 6 member 3(gene name synonym) psi-mi:wls_human(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22086798|imex:IM-27807-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0007626"(locomotory behavior)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0016600"(flotillin complex)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0010039"(response to iron ion)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|mint:Q01959|reactome:R-HSA-379401|reactome:R-HSA-442660|reactome:R-HSA-5619081|reactome:R-HSA-5660724|ensembl:ENSG00000142319(gene)|ensembl:ENSG00000276996(gene)|ensembl:ENST00000270349(transcript)|ensembl:ENST00000621716(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|refseq:NP_001035.1|dip:DIP-41827N refseq:NP_001180263.1|refseq:NP_001002292.3|refseq:NP_079187.3|ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061355"(Wnt protein secretion)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR009551(Protein of unknown function DUF1171)|mint:Q5T9L3|rcsb pdb:7KC4|reactome:R-HSA-3238698|go:"GO:0070062"(extracellular exosome) - - - figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/10/08 2019/10/15 rogid:mQKSGpeovNv4Sg8T2E3A8rVB2aY9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:Yl3c2Gib5SvIg1+yr6+7V8NzwnI false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BQI5 uniprotkb:Q5T9L3-1 intact:EBI-2690801|uniprotkb:Q6MZY6|uniprotkb:A6NLD1|uniprotkb:Q5VYE2|uniprotkb:A6NL81|uniprotkb:Q8IWC2|uniprotkb:Q68D76|uniprotkb:Q4LE32|uniprotkb:Q5VYE4|uniprotkb:Q5VYE3|ensembl:ENSP00000360076 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:sgip1_human(display_long)|uniprotkb:Endophilin-3-interacting protein(gene name synonym)|uniprotkb:SGIP1(gene name)|psi-mi:SGIP1(display_short) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0096"(pull down) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22086824|imex:IM-27807-129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006711037.1|refseq:NP_001295132.1|refseq:XP_016858000.1|refseq:XP_016858001.1|refseq:XP_016858023.1|refseq:XP_016858024.1|refseq:NP_115667.2|refseq:XP_005271321.1|refseq:XP_005271327.1|ensembl:ENSG00000118473(gene)|ensembl:ENST00000371037(transcript)|go:"GO:0002021"(response to dietary excess)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0008017"(microtubule binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097009"(energy homeostasis)|go:"GO:2000253"(positive regulation of feeding behavior)|interpro:IPR018808|interpro:IPR028565|interpro:IPR036168|interpro:IPR037984|mint:Q9BQI5|rcsb pdb:5AWR|rcsb pdb:5AWS|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:6A9Y|reactome:R-HSA-8856825|reactome:R-HSA-8856828 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Figure 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/10/08 2019/10/21 rogid:zFAutzD0AvL0d3TY1e1+TCO1vO09606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:frqjevxl/Z11oRqmwVG+dEEX3do false s tag:?-? sufficient binding region:493-541|glutathione s tranferase tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P23977 uniprotkb:Q5T9L3-1 intact:EBI-7347347|intact:MINT-4589571|ensembl:ENSRNOP00000047272|ensembl:ENSRNOP00000070728 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:sc6a3_rat(display_long)|uniprotkb:Slc6a3(gene name)|psi-mi:Slc6a3(display_short)|uniprotkb:Solute carrier family 6 member 3(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0096"(pull down) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22086834|imex:IM-27807-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3715|refseq:NP_036826.1|ensembl:ENSRNOG00000017302(gene)|ensembl:ENSRNOT00000040291(transcript)|ensembl:ENSRNOT00000079987(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0010039"(response to iron ion)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|mint:P23977|go:"GO:0016020"(membrane)|go:"GO:0016600"(flotillin complex)|reactome:R-RNO-379401|reactome:R-RNO-442660 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - function:Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals|comment:mint - figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/10/08 2019/10/21 rogid:kxghIhYdG3gb6ENVEYfL8ShET1A10116 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:2F6M3xGV1gZTUk5ja0xR41fnSr0 false - sufficient binding region:402-431|glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01959 uniprotkb:Q5T9L3 intact:EBI-6661445|ensembl:ENSP00000270349|ensembl:ENSP00000479597|uniprotkb:A2RUN4|uniprotkb:Q14996 intact:EBI-2868748|uniprotkb:Q8NC43|uniprotkb:Q7Z2Z9|uniprotkb:B2RNT2|intact:EBI-11046890|uniprotkb:Q5JRS7|ensembl:ENSP00000262348 psi-mi:sc6a3_human(display_long)|uniprotkb:SLC6A3(gene name)|psi-mi:SLC6A3(display_short)|uniprotkb:DAT1(gene name synonym)|uniprotkb:Solute carrier family 6 member 3(gene name synonym) psi-mi:wls_human(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0096"(pull down) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22087573|imex:IM-27807-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0007626"(locomotory behavior)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0016600"(flotillin complex)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0010039"(response to iron ion)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|mint:Q01959|reactome:R-HSA-379401|reactome:R-HSA-442660|reactome:R-HSA-5619081|reactome:R-HSA-5660724|ensembl:ENSG00000142319(gene)|ensembl:ENSG00000276996(gene)|ensembl:ENST00000270349(transcript)|ensembl:ENST00000621716(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|refseq:NP_001035.1|dip:DIP-41827N refseq:NP_001180263.1|refseq:NP_001002292.3|refseq:NP_079187.3|ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061355"(Wnt protein secretion)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR009551(Protein of unknown function DUF1171)|mint:Q5T9L3|rcsb pdb:7KC4|reactome:R-HSA-3238698|go:"GO:0070062"(extracellular exosome) - - - figure legend:Figure 3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/10/08 2019/10/15 rogid:mQKSGpeovNv4Sg8T2E3A8rVB2aY9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:Yl3c2Gib5SvIg1+yr6+7V8NzwnI false sufficient binding region:119-139|sufficient binding region:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P29274 uniprotkb:Q5T9L3-1 intact:EBI-2902702|ensembl:ENSP00000336630|ensembl:ENSP00000480012|ensembl:ENSP00000481552|ensembl:ENSP00000483102|uniprotkb:B2R7E0 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:aa2ar_human(display_long)|uniprotkb:ADORA2A(gene name)|psi-mi:ADORA2A(display_short)|uniprotkb:ADORA2(gene name synonym) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0096"(pull down) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22087605|imex:IM-27807-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128271(gene)|ensembl:ENST00000337539(transcript)|ensembl:ENST00000610595(transcript)|ensembl:ENST00000611543(transcript)|ensembl:ENST00000618076(transcript)|go:"GO:0001609"(G protein-coupled adenosine receptor activity)|go:"GO:0001963"(synaptic transmission, dopaminergic)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006909"(phagocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007417"(central nervous system development)|go:"GO:0007596"(blood coagulation)|go:"GO:0007600"(sensory perception)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012505"(endomembrane system)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014057"(positive regulation of acetylcholine secretion, neurotransmission)|go:"GO:0014061"(regulation of norepinephrine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0030673"(axolemma)|go:"GO:0031000"(response to caffeine)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0040013"(negative regulation of locomotion)|go:"GO:0042311"(vasodilation)|go:"GO:0042493"|go:"GO:0042755"(eating behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045938"(positive regulation of circadian sleep/wake cycle, sleep)|go:"GO:0046636"(negative regulation of alpha-beta T cell activation)|go:"GO:0048143"(astrocyte activation)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001513(Adenosine A2A receptor)|interpro:IPR001634(Adenosine receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P29274|rcsb pdb:1MMH|rcsb pdb:1UPE|rcsb pdb:2YDO|rcsb pdb:2YDV|rcsb pdb:3EML|rcsb pdb:3PWH|rcsb pdb:3QAK|rcsb pdb:3REY|rcsb pdb:3RFM|rcsb pdb:3UZA|rcsb pdb:3UZC|rcsb pdb:3VG9|rcsb pdb:3VGA|rcsb pdb:4UG2|rcsb pdb:4UHR|rcsb pdb:5G53|rcsb pdb:5IU4|rcsb pdb:5IU7|rcsb pdb:5IU8|rcsb pdb:5IUA|rcsb pdb:5IUB|rcsb pdb:5JTB|rcsb pdb:5K2A|rcsb pdb:5K2B|rcsb pdb:5K2C|rcsb pdb:5K2D|rcsb pdb:5MZJ|rcsb pdb:5MZP|rcsb pdb:5N2R|rcsb pdb:5NLX|rcsb pdb:5NM2|rcsb pdb:5NM4|rcsb pdb:5OLG|rcsb pdb:5OLH|rcsb pdb:5OLO|rcsb pdb:5OLV|rcsb pdb:5OLZ|rcsb pdb:5OM1|rcsb pdb:5OM4|rcsb pdb:4EIY|rcsb pdb:5UIG|rcsb pdb:5UVI|rcsb pdb:5WF5|rcsb pdb:5WF6|rcsb pdb:6AQF|rcsb pdb:6GDG|rcsb pdb:6GT3|rcsb pdb:6JZH|rcsb pdb:6LPJ|rcsb pdb:6LPK|rcsb pdb:6LPL|rcsb pdb:6MH8|rcsb pdb:6PS7|rcsb pdb:6S0L|rcsb pdb:6S0Q|rcsb pdb:6WQA|rcsb pdb:6ZDR|rcsb pdb:6ZDV|rcsb pdb:7ARO|reactome:R-HSA-187024|reactome:R-HSA-417973|reactome:R-HSA-418555|reactome:R-HSA-5683826|reactome:R-HSA-9660821|rcsb pdb:5VRA|refseq:NP_000666.2|refseq:NP_001265426.1|refseq:NP_001265427.1|refseq:NP_001265428.1|refseq:NP_001265429.1 ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/10/08 2019/10/21 rogid:3LgXP8J8wfsw4G5kVvY/8vVp4DA9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:V1e2yMlRQBE3ZLZVXjGSh69GcGU false flag tag:?-? glutathione s tranferase tag:n-n|sufficient binding region:493-541 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5T9L3-1 uniprotkb:P29274 intact:EBI-22114623|ensembl:ENSP00000262348 intact:EBI-2902702|ensembl:ENSP00000336630|ensembl:ENSP00000480012|ensembl:ENSP00000481552|ensembl:ENSP00000483102|uniprotkb:B2R7E0 psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:aa2ar_human(display_long)|uniprotkb:ADORA2A(gene name)|psi-mi:ADORA2A(display_short)|uniprotkb:ADORA2(gene name synonym) psi-mi:"MI:0096"(pull down) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22087623|imex:IM-27807-131 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) ensembl:ENSG00000128271(gene)|ensembl:ENST00000337539(transcript)|ensembl:ENST00000610595(transcript)|ensembl:ENST00000611543(transcript)|ensembl:ENST00000618076(transcript)|go:"GO:0001609"(G protein-coupled adenosine receptor activity)|go:"GO:0001963"(synaptic transmission, dopaminergic)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006909"(phagocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007417"(central nervous system development)|go:"GO:0007596"(blood coagulation)|go:"GO:0007600"(sensory perception)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012505"(endomembrane system)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014057"(positive regulation of acetylcholine secretion, neurotransmission)|go:"GO:0014061"(regulation of norepinephrine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0030673"(axolemma)|go:"GO:0031000"(response to caffeine)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0040013"(negative regulation of locomotion)|go:"GO:0042311"(vasodilation)|go:"GO:0042493"|go:"GO:0042755"(eating behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045938"(positive regulation of circadian sleep/wake cycle, sleep)|go:"GO:0046636"(negative regulation of alpha-beta T cell activation)|go:"GO:0048143"(astrocyte activation)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001513(Adenosine A2A receptor)|interpro:IPR001634(Adenosine receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P29274|rcsb pdb:1MMH|rcsb pdb:1UPE|rcsb pdb:2YDO|rcsb pdb:2YDV|rcsb pdb:3EML|rcsb pdb:3PWH|rcsb pdb:3QAK|rcsb pdb:3REY|rcsb pdb:3RFM|rcsb pdb:3UZA|rcsb pdb:3UZC|rcsb pdb:3VG9|rcsb pdb:3VGA|rcsb pdb:4UG2|rcsb pdb:4UHR|rcsb pdb:5G53|rcsb pdb:5IU4|rcsb pdb:5IU7|rcsb pdb:5IU8|rcsb pdb:5IUA|rcsb pdb:5IUB|rcsb pdb:5JTB|rcsb pdb:5K2A|rcsb pdb:5K2B|rcsb pdb:5K2C|rcsb pdb:5K2D|rcsb pdb:5MZJ|rcsb pdb:5MZP|rcsb pdb:5N2R|rcsb pdb:5NLX|rcsb pdb:5NM2|rcsb pdb:5NM4|rcsb pdb:5OLG|rcsb pdb:5OLH|rcsb pdb:5OLO|rcsb pdb:5OLV|rcsb pdb:5OLZ|rcsb pdb:5OM1|rcsb pdb:5OM4|rcsb pdb:4EIY|rcsb pdb:5UIG|rcsb pdb:5UVI|rcsb pdb:5WF5|rcsb pdb:5WF6|rcsb pdb:6AQF|rcsb pdb:6GDG|rcsb pdb:6GT3|rcsb pdb:6JZH|rcsb pdb:6LPJ|rcsb pdb:6LPK|rcsb pdb:6LPL|rcsb pdb:6MH8|rcsb pdb:6PS7|rcsb pdb:6S0L|rcsb pdb:6S0Q|rcsb pdb:6WQA|rcsb pdb:6ZDR|rcsb pdb:6ZDV|rcsb pdb:7ARO|reactome:R-HSA-187024|reactome:R-HSA-417973|reactome:R-HSA-418555|reactome:R-HSA-5683826|reactome:R-HSA-9660821|rcsb pdb:5VRA|refseq:NP_000666.2|refseq:NP_001265426.1|refseq:NP_001265427.1|refseq:NP_001265428.1|refseq:NP_001265429.1 - - - figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/10/08 2019/10/21 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rogid:3LgXP8J8wfsw4G5kVvY/8vVp4DA9606 rigid:V1e2yMlRQBE3ZLZVXjGSh69GcGU false s tag:?-?|sufficient binding region:493-541 sufficient binding region:312-412|glutathione s tranferase tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5T9L3-1 uniprotkb:Q5T9L3-1 intact:EBI-22114623|ensembl:ENSP00000262348 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0096"(pull down) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22091372|imex:IM-27807-99 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Figure 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/10/08 2019/10/21 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:EZRK8HVN2rYbIqraUT0hEQ7FXYg false - sufficient binding region:493-541|glutathione s tranferase tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P29274 uniprotkb:Q5T9L3 intact:EBI-2902702|ensembl:ENSP00000336630|ensembl:ENSP00000480012|ensembl:ENSP00000481552|ensembl:ENSP00000483102|uniprotkb:B2R7E0 intact:EBI-2868748|uniprotkb:Q8NC43|uniprotkb:Q7Z2Z9|uniprotkb:B2RNT2|intact:EBI-11046890|uniprotkb:Q5JRS7|ensembl:ENSP00000262348 psi-mi:aa2ar_human(display_long)|uniprotkb:ADORA2A(gene name)|psi-mi:ADORA2A(display_short)|uniprotkb:ADORA2(gene name synonym) psi-mi:wls_human(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22087599|imex:IM-27807-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128271(gene)|ensembl:ENST00000337539(transcript)|ensembl:ENST00000610595(transcript)|ensembl:ENST00000611543(transcript)|ensembl:ENST00000618076(transcript)|go:"GO:0001609"(G protein-coupled adenosine receptor activity)|go:"GO:0001963"(synaptic transmission, dopaminergic)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006909"(phagocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007417"(central nervous system development)|go:"GO:0007596"(blood coagulation)|go:"GO:0007600"(sensory perception)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012505"(endomembrane system)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014057"(positive regulation of acetylcholine secretion, neurotransmission)|go:"GO:0014061"(regulation of norepinephrine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0030673"(axolemma)|go:"GO:0031000"(response to caffeine)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0040013"(negative regulation of locomotion)|go:"GO:0042311"(vasodilation)|go:"GO:0042493"|go:"GO:0042755"(eating behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045938"(positive regulation of circadian sleep/wake cycle, sleep)|go:"GO:0046636"(negative regulation of alpha-beta T cell activation)|go:"GO:0048143"(astrocyte activation)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001513(Adenosine A2A receptor)|interpro:IPR001634(Adenosine receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P29274|rcsb pdb:1MMH|rcsb pdb:1UPE|rcsb pdb:2YDO|rcsb pdb:2YDV|rcsb pdb:3EML|rcsb pdb:3PWH|rcsb pdb:3QAK|rcsb pdb:3REY|rcsb pdb:3RFM|rcsb pdb:3UZA|rcsb pdb:3UZC|rcsb pdb:3VG9|rcsb pdb:3VGA|rcsb pdb:4UG2|rcsb pdb:4UHR|rcsb pdb:5G53|rcsb pdb:5IU4|rcsb pdb:5IU7|rcsb pdb:5IU8|rcsb pdb:5IUA|rcsb pdb:5IUB|rcsb pdb:5JTB|rcsb pdb:5K2A|rcsb pdb:5K2B|rcsb pdb:5K2C|rcsb pdb:5K2D|rcsb pdb:5MZJ|rcsb pdb:5MZP|rcsb pdb:5N2R|rcsb pdb:5NLX|rcsb pdb:5NM2|rcsb pdb:5NM4|rcsb pdb:5OLG|rcsb pdb:5OLH|rcsb pdb:5OLO|rcsb pdb:5OLV|rcsb pdb:5OLZ|rcsb pdb:5OM1|rcsb pdb:5OM4|rcsb pdb:4EIY|rcsb pdb:5UIG|rcsb pdb:5UVI|rcsb pdb:5WF5|rcsb pdb:5WF6|rcsb pdb:6AQF|rcsb pdb:6GDG|rcsb pdb:6GT3|rcsb pdb:6JZH|rcsb pdb:6LPJ|rcsb pdb:6LPK|rcsb pdb:6LPL|rcsb pdb:6MH8|rcsb pdb:6PS7|rcsb pdb:6S0L|rcsb pdb:6S0Q|rcsb pdb:6WQA|rcsb pdb:6ZDR|rcsb pdb:6ZDV|rcsb pdb:7ARO|reactome:R-HSA-187024|reactome:R-HSA-417973|reactome:R-HSA-418555|reactome:R-HSA-5683826|reactome:R-HSA-9660821|rcsb pdb:5VRA|refseq:NP_000666.2|refseq:NP_001265426.1|refseq:NP_001265427.1|refseq:NP_001265428.1|refseq:NP_001265429.1 refseq:NP_001180263.1|refseq:NP_001002292.3|refseq:NP_079187.3|ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061355"(Wnt protein secretion)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR009551(Protein of unknown function DUF1171)|mint:Q5T9L3|rcsb pdb:7KC4|reactome:R-HSA-3238698|go:"GO:0070062"(extracellular exosome) - - - figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/10/08 2019/10/15 rogid:3LgXP8J8wfsw4G5kVvY/8vVp4DA9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:V1e2yMlRQBE3ZLZVXjGSh69GcGU false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5T9L3-1 uniprotkb:Q5T9L3-1 intact:EBI-22114623|ensembl:ENSP00000262348 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0807"(comigration in gel electrophoresis) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-22091360|imex:IM-27807-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/10/08 2019/10/21 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:W5XPVG3cRiSMZ2Ul2/71R/TxX80 false glutathione s tranferase tag:n-n|sufficient binding region:493-541 glutathione s tranferase tag:n-n|sufficient binding region:493-541 2 0 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5T9L3-1 uniprotkb:Q5T9L3-1 intact:EBI-22114623|ensembl:ENSP00000262348 intact:EBI-22114623|ensembl:ENSP00000262348 psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22091384|imex:IM-27807-133 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) - - - figure legend:Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/10/08 2019/10/21 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:EZRK8HVN2rYbIqraUT0hEQ7FXYg false flag tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q5T9L3-1 uniprotkb:Q5T9L3 intact:EBI-22114623|ensembl:ENSP00000262348 intact:EBI-2868748|uniprotkb:Q8NC43|uniprotkb:Q7Z2Z9|uniprotkb:B2RNT2|intact:EBI-11046890|uniprotkb:Q5JRS7|ensembl:ENSP00000262348 psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:wls_human(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Petko et al. (2018) pubmed:28734904|imex:IM-27807 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22091400|imex:IM-27807-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent) refseq:NP_001180263.1|refseq:NP_001002292.3|refseq:NP_079187.3|ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061355"(Wnt protein secretion)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR009551(Protein of unknown function DUF1171)|mint:Q5T9L3|rcsb pdb:7KC4|reactome:R-HSA-3238698|go:"GO:0070062"(extracellular exosome) - - - figure legend:Fig. 5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/10/08 2019/10/21 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:EZRK8HVN2rYbIqraUT0hEQ7FXYg false flag tag:?-? myc tag:?-?|sufficient binding region:493-541 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)