#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P77165	uniprotkb:P77324	intact:EBI-1115563|uniprotkb:Q2MCD6|ensemblbacteria:AAC73389|ensemblbacteria:BAE76070	intact:EBI-1115552|uniprotkb:Q2MCD7|ensemblbacteria:AAC73388|ensemblbacteria:BAE76069	psi-mi:paoa_ecoli(display_long)|uniprotkb:paoA(gene name)|psi-mi:paoA(display_short)|uniprotkb:yagT(gene name synonym)|uniprotkb:JW0280(locus name)|uniprotkb:b0286(locus name)	psi-mi:paob_ecoli(display_long)|uniprotkb:paoB(gene name)|psi-mi:paoB(display_short)|uniprotkb:yagS(gene name synonym)|uniprotkb:JW0279(locus name)|uniprotkb:b0285(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Otrelo-Cardoso et al. (2014)	pubmed:27622978|imex:IM-27636	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21427148|wwpdb:5g5g|imex:IM-27636-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_000070700.1|refseq:NP_414820.1|interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR001041(Ferredoxin)|interpro:IPR006311(Twin-arginine translocation pathway signal)|ensemblbacteria:AAC73389(transcript)|ensemblbacteria:b0286(gene)|ensemblbacteria:BAE76070(gene)|ensemblbacteria:BAE76070(transcript)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|go:"GO:0047770"(carboxylate reductase activity)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|rcsb pdb:5G5G|rcsb pdb:5G5H|interpro:IPR036010|interpro:IPR036884	interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|refseq:NP_414819.1|interpro:IPR005107(CO dehydrogenase flavoprotein, C-terminal)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR002346(Molybdopterin dehydrogenase, FAD-binding)|refseq:WP_000643333.1|ensemblbacteria:AAC73388(transcript)|ensemblbacteria:b0285(gene)|ensemblbacteria:BAE76069(gene)|ensemblbacteria:BAE76069(transcript)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|go:"GO:0047770"(carboxylate reductase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071949"(FAD binding)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|rcsb pdb:5G5G|rcsb pdb:5G5H|interpro:IPR036318|interpro:IPR036683	-	-	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2019/05/28	2019/05/28	rogid:cvAMOY0im7DKWX9K6n3vGPWSLhU83333	rogid:xij2aYXxSnkQ3FCwhZ4OfxWByr483333	rigid:eeX7QbGBUoSbRPwaWnMjrIfaoQM	false	his tag:n-n	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P77165	uniprotkb:P77489	intact:EBI-1115563|uniprotkb:Q2MCD6|ensemblbacteria:AAC73389|ensemblbacteria:BAE76070	intact:EBI-1115437|uniprotkb:Q2MCD8|ensemblbacteria:AAC73387|ensemblbacteria:BAE76068	psi-mi:paoa_ecoli(display_long)|uniprotkb:paoA(gene name)|psi-mi:paoA(display_short)|uniprotkb:yagT(gene name synonym)|uniprotkb:JW0280(locus name)|uniprotkb:b0286(locus name)	psi-mi:paoc_ecoli(display_long)|uniprotkb:paoC(gene name)|psi-mi:paoC(display_short)|uniprotkb:yagR(gene name synonym)|uniprotkb:JW0278(locus name)|uniprotkb:b0284(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Otrelo-Cardoso et al. (2014)	pubmed:27622978|imex:IM-27636	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21427148|wwpdb:5g5g|imex:IM-27636-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_000070700.1|refseq:NP_414820.1|interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR001041(Ferredoxin)|interpro:IPR006311(Twin-arginine translocation pathway signal)|ensemblbacteria:AAC73389(transcript)|ensemblbacteria:b0286(gene)|ensemblbacteria:BAE76070(gene)|ensemblbacteria:BAE76070(transcript)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|go:"GO:0047770"(carboxylate reductase activity)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|rcsb pdb:5G5G|rcsb pdb:5G5H|interpro:IPR036010|interpro:IPR036884	refseq:WP_000667026.1|ensemblbacteria:AAC73387(transcript)|ensemblbacteria:b0284(gene)|ensemblbacteria:BAE76068(gene)|ensemblbacteria:BAE76068(transcript)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0030151"(molybdenum ion binding)|go:"GO:0042597"(periplasmic space)|go:"GO:0047770"(carboxylate reductase activity)|refseq:NP_414818.1|interpro:IPR000674(Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead)|interpro:IPR008274(Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding)|rcsb pdb:5G5G|rcsb pdb:5G5H|interpro:IPR036856|interpro:IPR037165	-	-	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2019/05/28	2019/05/28	rogid:cvAMOY0im7DKWX9K6n3vGPWSLhU83333	rogid:bpaniMXsFOnmRS+GmZkfSl2RaDs83333	rigid:eeX7QbGBUoSbRPwaWnMjrIfaoQM	false	his tag:n-n	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P77165	uniprotkb:P77324	intact:EBI-1115563|uniprotkb:Q2MCD6|ensemblbacteria:AAC73389|ensemblbacteria:BAE76070	intact:EBI-1115552|uniprotkb:Q2MCD7|ensemblbacteria:AAC73388|ensemblbacteria:BAE76069	psi-mi:paoa_ecoli(display_long)|uniprotkb:paoA(gene name)|psi-mi:paoA(display_short)|uniprotkb:yagT(gene name synonym)|uniprotkb:JW0280(locus name)|uniprotkb:b0286(locus name)	psi-mi:paob_ecoli(display_long)|uniprotkb:paoB(gene name)|psi-mi:paoB(display_short)|uniprotkb:yagS(gene name synonym)|uniprotkb:JW0279(locus name)|uniprotkb:b0285(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Otrelo-Cardoso et al. (2014)	pubmed:27622978|imex:IM-27636	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25400143|wwpdb:5g5h|imex:IM-27636-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_000070700.1|refseq:NP_414820.1|interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR001041(Ferredoxin)|interpro:IPR006311(Twin-arginine translocation pathway signal)|ensemblbacteria:AAC73389(transcript)|ensemblbacteria:b0286(gene)|ensemblbacteria:BAE76070(gene)|ensemblbacteria:BAE76070(transcript)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|go:"GO:0047770"(carboxylate reductase activity)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|rcsb pdb:5G5G|rcsb pdb:5G5H|interpro:IPR036010|interpro:IPR036884	interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|refseq:NP_414819.1|interpro:IPR005107(CO dehydrogenase flavoprotein, C-terminal)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR002346(Molybdopterin dehydrogenase, FAD-binding)|refseq:WP_000643333.1|ensemblbacteria:AAC73388(transcript)|ensemblbacteria:b0285(gene)|ensemblbacteria:BAE76069(gene)|ensemblbacteria:BAE76069(transcript)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|go:"GO:0047770"(carboxylate reductase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071949"(FAD binding)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|rcsb pdb:5G5G|rcsb pdb:5G5H|interpro:IPR036318|interpro:IPR036683	-	-	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2019/05/28	2020/01/20	rogid:cvAMOY0im7DKWX9K6n3vGPWSLhU83333	rogid:xij2aYXxSnkQ3FCwhZ4OfxWByr483333	rigid:eeX7QbGBUoSbRPwaWnMjrIfaoQM	false	his tag:n-n	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P77165	uniprotkb:P77489	intact:EBI-1115563|uniprotkb:Q2MCD6|ensemblbacteria:AAC73389|ensemblbacteria:BAE76070	intact:EBI-1115437|uniprotkb:Q2MCD8|ensemblbacteria:AAC73387|ensemblbacteria:BAE76068	psi-mi:paoa_ecoli(display_long)|uniprotkb:paoA(gene name)|psi-mi:paoA(display_short)|uniprotkb:yagT(gene name synonym)|uniprotkb:JW0280(locus name)|uniprotkb:b0286(locus name)	psi-mi:paoc_ecoli(display_long)|uniprotkb:paoC(gene name)|psi-mi:paoC(display_short)|uniprotkb:yagR(gene name synonym)|uniprotkb:JW0278(locus name)|uniprotkb:b0284(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Otrelo-Cardoso et al. (2014)	pubmed:27622978|imex:IM-27636	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25400143|wwpdb:5g5h|imex:IM-27636-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_000070700.1|refseq:NP_414820.1|interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR001041(Ferredoxin)|interpro:IPR006311(Twin-arginine translocation pathway signal)|ensemblbacteria:AAC73389(transcript)|ensemblbacteria:b0286(gene)|ensemblbacteria:BAE76070(gene)|ensemblbacteria:BAE76070(transcript)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|go:"GO:0047770"(carboxylate reductase activity)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|rcsb pdb:5G5G|rcsb pdb:5G5H|interpro:IPR036010|interpro:IPR036884	refseq:WP_000667026.1|ensemblbacteria:AAC73387(transcript)|ensemblbacteria:b0284(gene)|ensemblbacteria:BAE76068(gene)|ensemblbacteria:BAE76068(transcript)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0030151"(molybdenum ion binding)|go:"GO:0042597"(periplasmic space)|go:"GO:0047770"(carboxylate reductase activity)|refseq:NP_414818.1|interpro:IPR000674(Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead)|interpro:IPR008274(Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding)|rcsb pdb:5G5G|rcsb pdb:5G5H|interpro:IPR036856|interpro:IPR037165	-	-	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2019/05/28	2020/01/20	rogid:cvAMOY0im7DKWX9K6n3vGPWSLhU83333	rogid:bpaniMXsFOnmRS+GmZkfSl2RaDs83333	rigid:eeX7QbGBUoSbRPwaWnMjrIfaoQM	false	his tag:n-n	mutation:440-440	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P77165	uniprotkb:P77324	intact:EBI-1115563|uniprotkb:Q2MCD6|ensemblbacteria:AAC73389|ensemblbacteria:BAE76070	intact:EBI-1115552|uniprotkb:Q2MCD7|ensemblbacteria:AAC73388|ensemblbacteria:BAE76069	psi-mi:paoa_ecoli(display_long)|uniprotkb:paoA(gene name)|psi-mi:paoA(display_short)|uniprotkb:yagT(gene name synonym)|uniprotkb:JW0280(locus name)|uniprotkb:b0286(locus name)	psi-mi:paob_ecoli(display_long)|uniprotkb:paoB(gene name)|psi-mi:paoB(display_short)|uniprotkb:yagS(gene name synonym)|uniprotkb:JW0279(locus name)|uniprotkb:b0285(locus name)	psi-mi:"MI:0013"(biophysical)	Otrelo-Cardoso et al. (2014)	pubmed:27622978|imex:IM-27636	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21444423|imex:IM-27636-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_000070700.1|refseq:NP_414820.1|interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR001041(Ferredoxin)|interpro:IPR006311(Twin-arginine translocation pathway signal)|ensemblbacteria:AAC73389(transcript)|ensemblbacteria:b0286(gene)|ensemblbacteria:BAE76070(gene)|ensemblbacteria:BAE76070(transcript)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|go:"GO:0047770"(carboxylate reductase activity)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|rcsb pdb:5G5G|rcsb pdb:5G5H|interpro:IPR036010|interpro:IPR036884	interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|refseq:NP_414819.1|interpro:IPR005107(CO dehydrogenase flavoprotein, C-terminal)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR002346(Molybdopterin dehydrogenase, FAD-binding)|refseq:WP_000643333.1|ensemblbacteria:AAC73388(transcript)|ensemblbacteria:b0285(gene)|ensemblbacteria:BAE76069(gene)|ensemblbacteria:BAE76069(transcript)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|go:"GO:0047770"(carboxylate reductase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071949"(FAD binding)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|rcsb pdb:5G5G|rcsb pdb:5G5H|interpro:IPR036318|interpro:IPR036683	-	-	-	figure legend:Fig 2|comment:Cyanide treatment of the complex to remove the equatorial sulfido ligand made no difference to the spectra|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2019/05/28	2019/05/29	rogid:cvAMOY0im7DKWX9K6n3vGPWSLhU83333	rogid:xij2aYXxSnkQ3FCwhZ4OfxWByr483333	rigid:eeX7QbGBUoSbRPwaWnMjrIfaoQM	false	his tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P77165	uniprotkb:P77489	intact:EBI-1115563|uniprotkb:Q2MCD6|ensemblbacteria:AAC73389|ensemblbacteria:BAE76070	intact:EBI-1115437|uniprotkb:Q2MCD8|ensemblbacteria:AAC73387|ensemblbacteria:BAE76068	psi-mi:paoa_ecoli(display_long)|uniprotkb:paoA(gene name)|psi-mi:paoA(display_short)|uniprotkb:yagT(gene name synonym)|uniprotkb:JW0280(locus name)|uniprotkb:b0286(locus name)	psi-mi:paoc_ecoli(display_long)|uniprotkb:paoC(gene name)|psi-mi:paoC(display_short)|uniprotkb:yagR(gene name synonym)|uniprotkb:JW0278(locus name)|uniprotkb:b0284(locus name)	psi-mi:"MI:0013"(biophysical)	Otrelo-Cardoso et al. (2014)	pubmed:27622978|imex:IM-27636	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21444423|imex:IM-27636-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_000070700.1|refseq:NP_414820.1|interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR001041(Ferredoxin)|interpro:IPR006311(Twin-arginine translocation pathway signal)|ensemblbacteria:AAC73389(transcript)|ensemblbacteria:b0286(gene)|ensemblbacteria:BAE76070(gene)|ensemblbacteria:BAE76070(transcript)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|go:"GO:0047770"(carboxylate reductase activity)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|rcsb pdb:5G5G|rcsb pdb:5G5H|interpro:IPR036010|interpro:IPR036884	refseq:WP_000667026.1|ensemblbacteria:AAC73387(transcript)|ensemblbacteria:b0284(gene)|ensemblbacteria:BAE76068(gene)|ensemblbacteria:BAE76068(transcript)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0030151"(molybdenum ion binding)|go:"GO:0042597"(periplasmic space)|go:"GO:0047770"(carboxylate reductase activity)|refseq:NP_414818.1|interpro:IPR000674(Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead)|interpro:IPR008274(Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding)|rcsb pdb:5G5G|rcsb pdb:5G5H|interpro:IPR036856|interpro:IPR037165	-	-	-	figure legend:Fig 2|comment:Cyanide treatment of the complex to remove the equatorial sulfido ligand made no difference to the spectra|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2019/05/28	2019/05/29	rogid:cvAMOY0im7DKWX9K6n3vGPWSLhU83333	rogid:bpaniMXsFOnmRS+GmZkfSl2RaDs83333	rigid:eeX7QbGBUoSbRPwaWnMjrIfaoQM	false	his tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:17169"	intenz:1.2.99.6	intact:EBI-25400221|chebi:"CHEBI:3019"|chebi:"CHEBI:13875"|chebi:"CHEBI:22697"	intact:EBI-21444431|wwpdb:5G5G|wwpdb:5G5H|rhea:"RHEA:56856"	psi-mi:benzaldehyde(display_short)|psi-mi:"CHEBI:17169"(display_long)|intact:Artificial almond oil(synonym)|intact:Benzaldehyde(synonym)|intact:benzaldehyde(synonym)|intact:Benzanoaldehyde(synonym)|intact:Benzene carbaldehyde(synonym)|intact:Benzene carboxaldehyde(synonym)|intact:Benzenecarbonal(synonym)|intact:Benzenecarboxaldehyde(synonym)|intact:Benzenemethylal(synonym)|intact:Benzoic acid aldehyde(synonym)|intact:Benzoic aldehyde(synonym)|intact:Benzylaldehyde(synonym)|intact:Ethereal oil of bitter almonds(synonym)|intact:Phenylformaldehyde(synonym)|intact:Phenylmethanal(synonym)|intact:Synthetic oil of bitter almond(synonym)|intact:benzaldehyde(iupac name)	psi-mi:paoabc_ecoli(display_short)|psi-mi:1.2.99.6(display_long)|intact:PaoABC periplasmic aldehyde oxidoreductase (complex recommended name)|intact:"paoA:paoB:paoC"(complex systematic name)|intact:yagTSR complex(complex synonym)	psi-mi:"MI:0979"(oxidoreductase assay)	Otrelo-Cardoso et al. (2014)	pubmed:27622978|imex:IM-27636	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0945"(oxidoreductase activity electron transfer reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25400243|imex:IM-27636-10	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:1302"(stable complex)	-	go:"GO:0047770"(carboxylate reductase activity)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0110095"(cellular detoxification of aldehyde)|go:"GO:1990204"(oxidoreductase complex)|go:"GO:0042597"(periplasmic space)|intact:EBI-21427148(exp-evidence)|complex portal:CPX-4281(complex-primary)|evidence ontology:"ECO:0000353"|pubmed:23201473(see-also)|pubmed:27622978(see-also)	go:"GO:0047770"(carboxylate reductase activity)	-	curated-complex:A periplasmic aldehyde oxidoreductase that oxidises aldehydes to the corresponding carboxylic acids. Preferentially detoxifies aromatic aldehydes, excluding purines. At high doses, aromatic aldehydes can act as antimicrobial agents.|complex-properties:The 135 kDa enzyme complex creates a set of redox centers involved in electron transfer and contains a transition metal molybdenum as a biologically active cofactor.|complex-assembly:Heterotrimer	figure legend:Fig. 7|kinetics:The PaoC-R440H variant showed a slightly increased Km and a slightly lower kcat in comparison to the wild-type.  The Km values of the PaoC-R440 K variant were twice as high in comparison to the wild-type, while the kcat for this variant was about 3-times reduced.|kinetic_conditions:pH optimum for the catalytic efficiency is at pH 4.0 for the wild-  type and the PaoC-R440H variant and at pH 4.5 for the PaoC-  R440 K variant.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	km:1.32x10^-5(molar)	2019/05/28	2020/01/20	-	-	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)