#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P25100	uniprotkb:P46939	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40|ensembl:ENSP00000356515	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273895|imex:IM-26901-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	ensembl:ENSP00000356515|refseq:XP_011534408.1|refseq:NP_009055.2|refseq:XP_005267187.1|dip:DIP-711N|ensembl:ENSG00000152818(gene)|ensembl:ENST00000367545(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017166"(vinculin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665	-	-	-	figure legend:Table 1-1, Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/28	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:metWqbqGtzonNZ1mgNjlFrenuI89606	rigid:BbBcAsVxWsy9pPPhmVyjqfr2l0c	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q9Y4J8	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-949471|ensembl:ENSP00000382064|uniprotkb:O15332|uniprotkb:O15333|uniprotkb:O75697|uniprotkb:Q13197|uniprotkb:Q13198|uniprotkb:Q13199|uniprotkb:Q13498|uniprotkb:Q13499|uniprotkb:Q13500|uniprotkb:A8MUY4|uniprotkb:A8K541|uniprotkb:M0QYX6|uniprotkb:A8MSZ0|uniprotkb:Q9BS59|uniprotkb:B4DIU8|uniprotkb:B4DIR0|uniprotkb:B4DGS6|uniprotkb:M0R397|uniprotkb:Q59GK7	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:dtna_human(display_long)|uniprotkb:Alpha-dystrobrevin(gene name synonym)|uniprotkb:Dystrophin-related protein 3(gene name synonym)|uniprotkb:DTNA(gene name)|psi-mi:DTNA(display_short)|uniprotkb:DRP3(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273895|imex:IM-26901-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	ensembl:ENSG00000134769(gene)|ensembl:ENST00000399113(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045202"(synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:Q9Y4J8|rcsb pdb:2E5R|interpro:IPR000433(Zinc finger, ZZ-type)|refseq:NP_001185873.1|refseq:NP_001381.2|refseq:NP_001382.2|refseq:NP_001383.2|refseq:NP_116757.2|refseq:NP_116760.2|refseq:NP_116761.2|refseq:NP_116762.2|refseq:NP_116763.1|refseq:XP_011524155.1|refseq:NP_001121647.1|refseq:NP_001185867.1|refseq:NP_001185868.1|refseq:NP_001185871.1|refseq:NP_001185869.1|refseq:NP_001185874.1|refseq:NP_001185870.1|refseq:XP_016881066.1|refseq:XP_016881073.1|refseq:XP_016881076.1|refseq:XP_016881077.1|refseq:XP_016881078.1|refseq:XP_016881079.1|refseq:XP_016881080.1|refseq:XP_016881089.1|refseq:XP_016881090.1|refseq:XP_016881091.1	-	-	-	figure legend:Table 1-1, Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/28	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:9HaDKLthoXmwdYDzbEer3CRN3O09606	rigid:BbBcAsVxWsy9pPPhmVyjqfr2l0c	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:P11532	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-295827|uniprotkb:Q9UCW3|uniprotkb:Q9UCW4|uniprotkb:Q02295|uniprotkb:Q14169|uniprotkb:Q14170|uniprotkb:Q5JYU0|uniprotkb:Q7KZ48|intact:EBI-11041646|uniprotkb:A1L0U9|uniprotkb:Q8N754|uniprotkb:E9PDN1|uniprotkb:Q6NSJ9|intact:EBI-12189729|intact:EBI-22423597|intact:EBI-12702600|uniprotkb:E7EQR9|uniprotkb:E7EQS5|uniprotkb:E7ESB2|uniprotkb:E9PDN5|uniprotkb:F5GZY3|uniprotkb:F8VX32|intact:EBI-28985510	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:dmd_human(display_long)|uniprotkb:DMD(gene name)|psi-mi:DMD(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273895|imex:IM-26901-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_000100.2|refseq:NP_003997.1|refseq:NP_004000.1|refseq:NP_004001.1|refseq:NP_004002.2|refseq:NP_004003.1|refseq:NP_004004.1|refseq:NP_004005.1|refseq:NP_004008.1|refseq:NP_004009.1|refseq:NP_004010.1|refseq:NP_004011.2|refseq:NP_004012.1|refseq:NP_004013.1|refseq:NP_004014.1|refseq:NP_004006.1|refseq:NP_004007.1|ensembl:ENST00000682600|ensembl:ENSP00000507640|ensembl:ENST00000361471|ensembl:ENSP00000354464|ensembl:ENSG00000198947|ensembl:ENST00000378680|ensembl:ENSP00000367951|ensembl:ENST00000378702|ensembl:ENSP00000367974|ensembl:ENST00000378723|ensembl:ENSP00000367997|mint:P11532|dip:DIP-32593N|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009986"(cell surface)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|rcsb pdb:1DXX|rcsb pdb:1EG3|rcsb pdb:1EG4|rcsb pdb:3UUN|reactome:R-HSA-3000171|reactome:R-HSA-390522	-	-	-	figure legend:Table 1-1, Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/28	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:gUFSTsQjsZpAmGI3+6ZPmUebofA9606	rigid:BbBcAsVxWsy9pPPhmVyjqfr2l0c	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q9UBT7	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-514206|uniprotkb:O76084|uniprotkb:Q53FQ2|uniprotkb:Q5JTQ7|uniprotkb:Q5JTQ8|uniprotkb:Q9Y401|uniprotkb:B5BU47|ensembl:ENSP00000320434	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:ctnl1_human(display_long)|uniprotkb:Catenin alpha-like protein 1(gene name synonym)|uniprotkb:Alpha-catenin-related protein(gene name synonym)|uniprotkb:CTNNAL1(gene name)|psi-mi:CTNNAL1(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273895|imex:IM-26901-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_003789.1|refseq:NP_001273903.1|dip:DIP-33236N|ensembl:ENSG00000119326(gene)|ensembl:ENST00000325551(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030045|interpro:IPR036723|mint:Q9UBT7	-	-	-	figure legend:Table 1-1, Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/28	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:4XpDxeBmUk7NAT/aAAhl0c8Sc1w9606	rigid:BbBcAsVxWsy9pPPhmVyjqfr2l0c	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q13425	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-80411|ensembl:ENSP00000338191|uniprotkb:Q9BY09	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:sntb2_human(display_long)|uniprotkb:SNT2B2(gene name synonym)|uniprotkb:SNTB2(gene name)|psi-mi:SNTB2(display_short)|uniprotkb:D16S2531E(gene name synonym)|uniprotkb:SNTL(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 2(gene name synonym)|uniprotkb:Syntrophin-3(gene name synonym)|uniprotkb:Syntrophin-like(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273895|imex:IM-26901-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0016020"(membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028550|interpro:IPR036034|interpro:IPR041428|mint:Q13425|rcsb pdb:2VRF|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000168807(gene)|ensembl:ENST00000336278(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_006741.1	-	-	-	figure legend:Table 1-1, Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/28	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:SABgmvArdLH93OpFobs/L3BleVY9606	rigid:BbBcAsVxWsy9pPPhmVyjqfr2l0c	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q13884	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-295843|uniprotkb:O14912|uniprotkb:Q4KMG8|uniprotkb:A8K9E0|ensembl:ENSP00000378965|ensembl:ENSP00000431124	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:sntb1_human(display_long)|uniprotkb:SNTB1(gene name)|psi-mi:SNTB1(display_short)|uniprotkb:SNT2B1(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 1(gene name synonym)|uniprotkb:Tax interaction protein 43(gene name synonym)|uniprotkb:Syntrophin-2(gene name synonym)|uniprotkb:BSYN2(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273895|imex:IM-26901-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:XP_011515541.1|refseq:NP_066301.1|dip:DIP-466N|ensembl:ENSG00000172164(gene)|ensembl:ENST00000395601(transcript)|ensembl:ENST00000517992(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR036034|interpro:IPR041428|mint:Q13884	-	-	-	figure legend:Table 1-1, Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/28	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:ysg02ZmUoj12kFHjpHE68vA1lUs9606	rigid:BbBcAsVxWsy9pPPhmVyjqfr2l0c	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q14160	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273895|imex:IM-26901-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:Table 1-1, Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/28	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rigid:BbBcAsVxWsy9pPPhmVyjqfr2l0c	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96S55	uniprotkb:P28223	intact:EBI-2513471|ensembl:ENSP00000370150|ensembl:ENSP00000477551|uniprotkb:Q9NRJ6|uniprotkb:Q5W0E2|uniprotkb:Q53EP6|uniprotkb:Q8WV26|uniprotkb:Q5W0E4|uniprotkb:Q59ET8|uniprotkb:Q9H681|uniprotkb:B2RDB0	intact:EBI-6656333|ensembl:ENSP00000437737|uniprotkb:B2RAC5|uniprotkb:B4DZ79|uniprotkb:F5GWE8|uniprotkb:Q5T8C0	psi-mi:wrip1_human(display_long)|uniprotkb:WRNIP1(gene name)|psi-mi:WRNIP1(display_short)|uniprotkb:WHIP(gene name synonym)|uniprotkb:Werner helicase-interacting protein 1(gene name synonym)	psi-mi:5ht2a_human(display_long)|uniprotkb:HTR2A(gene name)|psi-mi:HTR2A(display_short)|uniprotkb:HTR2(gene name synonym)|uniprotkb:Serotonin receptor 2A(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273912|imex:IM-26901-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000124535(gene)|ensembl:ENST00000380773(transcript)|ensembl:ENST00000618555(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR021886|interpro:IPR027417|interpro:IPR032423|interpro:IPR040539|mint:Q96S55|rcsb pdb:3VHS|rcsb pdb:3VHT|go:"GO:0017116"(single-stranded DNA helicase activity)|refseq:NP_064520.2|refseq:NP_569079.1	ensembl:ENSG00000102468(gene)|ensembl:ENST00000542664(transcript)|go:"GO:0001587"(Gq/11-coupled serotonin receptor activity)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007568"(aging)|go:"GO:0007613"(memory)|go:"GO:0008219"(cell death)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010513"(positive regulation of phosphatidylinositol biosynthetic process)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014824"(artery smooth muscle contraction)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030431"(sleep)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044380"(protein localization to cytoskeleton)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0007208"(phospholipase C-activating serotonin receptor signaling pathway)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0007210"(serotonin receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051967"(negative regulation of synaptic transmission, glutamatergic)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070852"(cell body fiber)|go:"GO:0071886"("1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding")|go:"GO:0098664"(G protein-coupled serotonin receptor signaling pathway)|go:"GO:0098666"(G protein-coupled serotonin receptor complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000455(5-Hydroxytryptamine 2A receptor)|interpro:IPR002231(5-Hydroxytryptamine receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6A93|rcsb pdb:6A94|rcsb pdb:6WGT|rcsb pdb:6WH4|rcsb pdb:6WHA|reactome:R-HSA-390666|reactome:R-HSA-416476|go:"GO:0051378"(serotonin binding)|refseq:NP_000612.1|refseq:NP_001159419.1|dip:DIP-41844N	-	-	-	figure legend:Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:Q8qVSqItgTO7sbWGAQ3XAoFFUr89606	rogid:wwxBh+3zPyTL6rfTCnViWTHndzo9606	rigid:3lzl3bK0I4G+hP1J+cDZXr6O/oM	false	-	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P41595	uniprotkb:Q96S55	intact:EBI-7474947|uniprotkb:Q53TI1|uniprotkb:Q62221|uniprotkb:Q6P523|intact:MINT-444010|uniprotkb:B2R9D5|ensembl:ENSP00000258400	intact:EBI-2513471|ensembl:ENSP00000370150|ensembl:ENSP00000477551|uniprotkb:Q9NRJ6|uniprotkb:Q5W0E2|uniprotkb:Q53EP6|uniprotkb:Q8WV26|uniprotkb:Q5W0E4|uniprotkb:Q59ET8|uniprotkb:Q9H681|uniprotkb:B2RDB0	psi-mi:5ht2b_human(display_long)|uniprotkb:HTR2B(gene name)|psi-mi:HTR2B(display_short)|uniprotkb:Serotonin receptor 2B(gene name synonym)	psi-mi:wrip1_human(display_long)|uniprotkb:WRNIP1(gene name)|psi-mi:WRNIP1(display_short)|uniprotkb:WHIP(gene name synonym)|uniprotkb:Werner helicase-interacting protein 1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273928|imex:IM-26901-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001307687.1|refseq:NP_000858.3|ensembl:ENSG00000135914(gene)|ensembl:ENST00000258400(transcript)|go:"GO:0001587"(Gq/11-coupled serotonin receptor activity)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007208"(phospholipase C-activating serotonin receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007610"(behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010513"(positive regulation of phosphatidylinositol biosynthetic process)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014827"(intestine smooth muscle contraction)|go:"GO:0016310"(phosphorylation)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045202"(synapse)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051378"(serotonin binding)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071502"(cellular response to temperature stimulus)|go:"GO:0098664"(G protein-coupled serotonin receptor signaling pathway)|go:"GO:0098666"(G protein-coupled serotonin receptor complex)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000482(5-Hydroxytryptamine 2B receptor)|interpro:IPR002231(5-Hydroxytryptamine receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:4IB4|rcsb pdb:4NC3|rcsb pdb:5TUD|rcsb pdb:5TVN|rcsb pdb:6DRX|rcsb pdb:6DRY|rcsb pdb:6DRZ|rcsb pdb:6DS0|reactome:R-HSA-390666|reactome:R-HSA-416476|go:"GO:0050795"(regulation of behavior)	ensembl:ENSG00000124535(gene)|ensembl:ENST00000380773(transcript)|ensembl:ENST00000618555(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR021886|interpro:IPR027417|interpro:IPR032423|interpro:IPR040539|mint:Q96S55|rcsb pdb:3VHS|rcsb pdb:3VHT|go:"GO:0017116"(single-stranded DNA helicase activity)|refseq:NP_064520.2|refseq:NP_569079.1	-	comment:mint|function:"This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system"	-	figure legend:Table 1-3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:PvEyuvigR2bXgqBgf+SUn6RhZTk9606	rogid:Q8qVSqItgTO7sbWGAQ3XAoFFUr89606	rigid:QQJ65fxCzum3xWkxRMGj1X7g81E	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HD26	uniprotkb:P30872	intact:EBI-349832|uniprotkb:A6NM30|uniprotkb:Q59FS4|uniprotkb:Q969U8|ensembl:ENSP00000357484	intact:EBI-21273948|ensembl:ENSP00000267377	psi-mi:gopc_human(display_long)|uniprotkb:CAL(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)	psi-mi:ssr1_human(display_long)|uniprotkb:SRIF-2(gene name synonym)|uniprotkb:SSTR1(gene name)|psi-mi:SSTR1(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273938|imex:IM-26901-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001017408.1|refseq:NP_065132.1|go:"GO:0043004"(cytoplasmic sequestering of CFTR protein)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045176"(apical protein localization)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR038879|mint:Q9HD26|rcsb pdb:2DC2|rcsb pdb:2LOB|rcsb pdb:4E34|rcsb pdb:4E35|rcsb pdb:4JOE|rcsb pdb:4JOF|rcsb pdb:4JOG|rcsb pdb:4JOH|rcsb pdb:4JOJ|rcsb pdb:4JOK|rcsb pdb:4JOP|rcsb pdb:4JOR|rcsb pdb:4K6Y|rcsb pdb:4K72|rcsb pdb:4K75|rcsb pdb:4K76|rcsb pdb:4K78|rcsb pdb:4NMO|rcsb pdb:4NMP|rcsb pdb:4NMQ|rcsb pdb:4NMR|rcsb pdb:4NMS|rcsb pdb:4NMT|go:"GO:0042802"(identical protein binding)|rcsb pdb:4NMV|rcsb pdb:4Q6H|rcsb pdb:4Q6S|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6OV7|rcsb pdb:6V84|rcsb pdb:6XNJ|reactome:R-HSA-5627083|reactome:R-HSA-9013406|ensembl:ENSG00000047932(gene)|ensembl:ENST00000368498(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010360"(negative regulation of anion channel activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0032991"(protein-containing complex)	ensembl:ENSG00000139874(gene)|ensembl:ENST00000267377(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004994"(somatostatin receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0021549"(cerebellum development)|go:"GO:0030900"(forebrain development)|go:"GO:0042277"(peptide binding)|go:"GO:0042594"(response to starvation)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000586(Somatostatin receptor)|interpro:IPR001116(Somatostatin receptor, type 1)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-375276|reactome:R-HSA-418594|go:"GO:0005887"(integral component of plasma membrane)|refseq:NP_001040.1	-	-	-	figure legend:Table 1-4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:bXzu5wvJifZwB+Q52cgC4tZQl/k9606	rogid:FtSQPO0zdG69nJSBogdMkafkrV49606	rigid:FkfNbHpm3n7llzS7mbuUWfXwMcM	false	-	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P32745	uniprotkb:Q9H4A6	intact:EBI-6266935|ensembl:ENSP00000480971|ensembl:ENSP00000481325|uniprotkb:A8K550|uniprotkb:Q53ZR7	intact:EBI-2465479|uniprotkb:Q9UIW5|ensembl:ENSP00000265070	psi-mi:ssr3_human(display_long)|uniprotkb:SSTR3(gene name)|psi-mi:SSTR3(display_short)|uniprotkb:SSR-28(gene name synonym)	psi-mi:golp3_human(display_long)|uniprotkb:GOLPH3(gene name)|psi-mi:GOLPH3(display_short)|uniprotkb:GPP34(gene name synonym)|uniprotkb:Coat protein GPP34(gene name synonym)|uniprotkb:Mitochondrial DNA absence factor(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273980|imex:IM-26901-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000278195(gene)|ensembl:ENST00000610913(transcript)|ensembl:ENST00000617123(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004994"(somatostatin receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008628"(hormone-mediated apoptotic signaling pathway)|go:"GO:0021549"(cerebellum development)|go:"GO:0030900"(forebrain development)|go:"GO:0042277"(peptide binding)|go:"GO:0042594"(response to starvation)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0060170"(ciliary membrane)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000586(Somatostatin receptor)|interpro:IPR001856(Somatostatin receptor, type 3)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P32745|reactome:R-HSA-375276|reactome:R-HSA-418594|reactome:R-HSA-5620922|refseq:XP_011528651.1|refseq:XP_005261778.1|refseq:NP_001042.1|refseq:XP_006724374.1|refseq:NP_001265616.1|refseq:XP_016884412.1|refseq:XP_016884413.1	refseq:NP_071413.1|ensembl:ENSG00000113384(gene)|ensembl:ENST00000265070(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0009306"(protein secretion)|go:"GO:0010467"(gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090164"(asymmetric Golgi ribbon formation)|interpro:IPR008628(Golgi phosphoprotein 3)|interpro:IPR038261|mint:Q9H4A6|rcsb pdb:3KN1	-	-	-	figure legend:Table 1-5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:qSna7iphTpLgG05n7OyhDpvYX4A9606	rogid:tHHREhHksCP+Yf9FzycM9cI+wkc9606	rigid:Qo30W5DjElh6WemaLJZ7A/iqQPE	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P32745	uniprotkb:P68400	intact:EBI-6266935|ensembl:ENSP00000480971|ensembl:ENSP00000481325|uniprotkb:A8K550|uniprotkb:Q53ZR7	intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6	psi-mi:ssr3_human(display_long)|uniprotkb:SSTR3(gene name)|psi-mi:SSTR3(display_short)|uniprotkb:SSR-28(gene name synonym)	psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273980|imex:IM-26901-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000278195(gene)|ensembl:ENST00000610913(transcript)|ensembl:ENST00000617123(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004994"(somatostatin receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008628"(hormone-mediated apoptotic signaling pathway)|go:"GO:0021549"(cerebellum development)|go:"GO:0030900"(forebrain development)|go:"GO:0042277"(peptide binding)|go:"GO:0042594"(response to starvation)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0060170"(ciliary membrane)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000586(Somatostatin receptor)|interpro:IPR001856(Somatostatin receptor, type 3)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P32745|reactome:R-HSA-375276|reactome:R-HSA-418594|reactome:R-HSA-5620922|refseq:XP_011528651.1|refseq:XP_005261778.1|refseq:NP_001042.1|refseq:XP_006724374.1|refseq:NP_001265616.1|refseq:XP_016884412.1|refseq:XP_016884413.1	rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N	-	-	-	figure legend:Table 1-5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:qSna7iphTpLgG05n7OyhDpvYX4A9606	rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606	rigid:Qo30W5DjElh6WemaLJZ7A/iqQPE	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P31391	uniprotkb:Q04917	intact:EBI-21274002|ensembl:ENSP00000255008|uniprotkb:Q17RM1|uniprotkb:Q17RM3|uniprotkb:Q9UIY1	intact:EBI-306940|ensembl:ENSP00000248975|intact:EBI-11759595	psi-mi:ssr4_human(display_long)|uniprotkb:SSTR4(gene name)|psi-mi:SSTR4(display_short)	psi-mi:1433f_human(display_long)|uniprotkb:YWHAH(gene name)|psi-mi:YWHAH(display_short)|uniprotkb:YWHA1(gene name synonym)|uniprotkb:Protein AS1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273991|imex:IM-26901-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132671(gene)|ensembl:ENST00000255008(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004994"(somatostatin receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016477"(cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0042277"(peptide binding)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0090238"(positive regulation of arachidonic acid secretion)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000586(Somatostatin receptor)|interpro:IPR001512(Somatostatin receptor, type 4)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-418594|reactome:R-HSA-375276|refseq:NP_001043.2	go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:Q04917|rcsb pdb:2C63|rcsb pdb:2C74|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|ensembl:ENSG00000128245(gene)|ensembl:ENST00000248975(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_003396.1|dip:DIP-27566N	-	-	-	figure legend:Table 1-6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:BVFXpopEBt4Zg1GicwjXpJDeOhs9606	rogid:VhFYPSsW3IRC388FTlmwwN37HnU9606	rigid:5GmVgD0gplov5R9WbQql370tr6U	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P31391	uniprotkb:P62258	intact:EBI-21274002|ensembl:ENSP00000255008|uniprotkb:Q17RM1|uniprotkb:Q17RM3|uniprotkb:Q9UIY1	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	psi-mi:ssr4_human(display_long)|uniprotkb:SSTR4(gene name)|psi-mi:SSTR4(display_short)	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273991|imex:IM-26901-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132671(gene)|ensembl:ENST00000255008(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004994"(somatostatin receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016477"(cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0042277"(peptide binding)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0090238"(positive regulation of arachidonic acid secretion)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000586(Somatostatin receptor)|interpro:IPR001512(Somatostatin receptor, type 4)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-418594|reactome:R-HSA-375276|refseq:NP_001043.2	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447	-	-	-	figure legend:Table 1-6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:BVFXpopEBt4Zg1GicwjXpJDeOhs9606	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	rigid:5GmVgD0gplov5R9WbQql370tr6U	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P31391	uniprotkb:P31946	intact:EBI-21274002|ensembl:ENSP00000255008|uniprotkb:Q17RM1|uniprotkb:Q17RM3|uniprotkb:Q9UIY1	intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930	psi-mi:ssr4_human(display_long)|uniprotkb:SSTR4(gene name)|psi-mi:SSTR4(display_short)	psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273991|imex:IM-26901-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132671(gene)|ensembl:ENST00000255008(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004994"(somatostatin receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016477"(cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0042277"(peptide binding)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0090238"(positive regulation of arachidonic acid secretion)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000586(Somatostatin receptor)|interpro:IPR001512(Somatostatin receptor, type 4)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-418594|reactome:R-HSA-375276|refseq:NP_001043.2	refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N	-	-	-	figure legend:Table 1-6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:BVFXpopEBt4Zg1GicwjXpJDeOhs9606	rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606	rigid:5GmVgD0gplov5R9WbQql370tr6U	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P49682	uniprotkb:Q8N2G8	intact:EBI-12836456|ensembl:ENSP00000362797|uniprotkb:B2R982|uniprotkb:O15185|uniprotkb:Q7Z710|uniprotkb:Q9P2T4|uniprotkb:Q9P2T5	intact:EBI-10985637|uniprotkb:B4DQS4|uniprotkb:E9PDB5|uniprotkb:Q9BXM6|ensembl:ENSP00000301671|ensembl:ENSP00000467585	psi-mi:cxcr3_human(display_long)|uniprotkb:CXCR3(gene name)|psi-mi:CXCR3(display_short)|uniprotkb:CKR-L2(gene name synonym)|uniprotkb:G protein-coupled receptor 9(gene name synonym)|uniprotkb:GPR9(gene name synonym)|uniprotkb:Interferon-inducible protein 10 receptor(gene name synonym)	psi-mi:ghdc_human(display_long)|uniprotkb:GHDC(gene name)|psi-mi:GHDC(display_short)|uniprotkb:D11LGP1E(gene name synonym)|uniprotkb:LGP1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274037|imex:IM-26901-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0038023"(signaling receptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060326"(cell chemotaxis)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR004070(C-X-C chemokine receptor, type 3)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0030155"(regulation of cell adhesion)|ensembl:ENSG00000186810(gene)|ensembl:ENST00000373693(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019956"(chemokine binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019958"(C-X-C chemokine binding)|refseq:NP_001136269.1|refseq:NP_001495.1|refseq:XP_016884924.1|dip:DIP-5891N	refseq:NP_001136095.1|refseq:NP_115873.1|ensembl:ENSG00000167925(gene)|ensembl:ENST00000301671(transcript)|ensembl:ENST00000587427(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016881"(acid-amino acid ligase activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035580"(specific granule lumen)|interpro:IPR004993(GH3 auxin-responsive promoter)|reactome:R-HSA-6798695	-	-	-	figure legend:Table 1-8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:P9WxnLkV6IH50a6feWDd6KsoNlA9606	rogid:AlZkawSGl/YLF3onfXtqK0vWf4k9606	rigid:O6AohyYV8DLltRiMcf9I3xRuvaQ	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P49682	uniprotkb:Q9HD26	intact:EBI-12836456|ensembl:ENSP00000362797|uniprotkb:B2R982|uniprotkb:O15185|uniprotkb:Q7Z710|uniprotkb:Q9P2T4|uniprotkb:Q9P2T5	intact:EBI-349832|uniprotkb:A6NM30|uniprotkb:Q59FS4|uniprotkb:Q969U8|ensembl:ENSP00000357484	psi-mi:cxcr3_human(display_long)|uniprotkb:CXCR3(gene name)|psi-mi:CXCR3(display_short)|uniprotkb:CKR-L2(gene name synonym)|uniprotkb:G protein-coupled receptor 9(gene name synonym)|uniprotkb:GPR9(gene name synonym)|uniprotkb:Interferon-inducible protein 10 receptor(gene name synonym)	psi-mi:gopc_human(display_long)|uniprotkb:CAL(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274037|imex:IM-26901-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0038023"(signaling receptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060326"(cell chemotaxis)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR004070(C-X-C chemokine receptor, type 3)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0030155"(regulation of cell adhesion)|ensembl:ENSG00000186810(gene)|ensembl:ENST00000373693(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019956"(chemokine binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019958"(C-X-C chemokine binding)|refseq:NP_001136269.1|refseq:NP_001495.1|refseq:XP_016884924.1|dip:DIP-5891N	refseq:NP_001017408.1|refseq:NP_065132.1|go:"GO:0043004"(cytoplasmic sequestering of CFTR protein)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045176"(apical protein localization)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR038879|mint:Q9HD26|rcsb pdb:2DC2|rcsb pdb:2LOB|rcsb pdb:4E34|rcsb pdb:4E35|rcsb pdb:4JOE|rcsb pdb:4JOF|rcsb pdb:4JOG|rcsb pdb:4JOH|rcsb pdb:4JOJ|rcsb pdb:4JOK|rcsb pdb:4JOP|rcsb pdb:4JOR|rcsb pdb:4K6Y|rcsb pdb:4K72|rcsb pdb:4K75|rcsb pdb:4K76|rcsb pdb:4K78|rcsb pdb:4NMO|rcsb pdb:4NMP|rcsb pdb:4NMQ|rcsb pdb:4NMR|rcsb pdb:4NMS|rcsb pdb:4NMT|go:"GO:0042802"(identical protein binding)|rcsb pdb:4NMV|rcsb pdb:4Q6H|rcsb pdb:4Q6S|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6OV7|rcsb pdb:6V84|rcsb pdb:6XNJ|reactome:R-HSA-5627083|reactome:R-HSA-9013406|ensembl:ENSG00000047932(gene)|ensembl:ENST00000368498(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010360"(negative regulation of anion channel activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0032991"(protein-containing complex)	-	-	-	figure legend:Table 1-8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:P9WxnLkV6IH50a6feWDd6KsoNlA9606	rogid:bXzu5wvJifZwB+Q52cgC4tZQl/k9606	rigid:O6AohyYV8DLltRiMcf9I3xRuvaQ	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00519	uniprotkb:P25025	intact:EBI-1389829|uniprotkb:Q52M86|uniprotkb:Q5TDF8|uniprotkb:D3DQ19|ensembl:ENSP00000243167	intact:EBI-2835281|uniprotkb:Q8IUZ1|uniprotkb:Q9P2T7|uniprotkb:Q9P2T6|ensembl:ENSP00000319635	psi-mi:faah1_human(display_long)|uniprotkb:Oleamide hydrolase 1(gene name synonym)|uniprotkb:Anandamide amidohydrolase 1(gene name synonym)|uniprotkb:FAAH(gene name)|psi-mi:FAAH(display_short)|uniprotkb:FAAH1(gene name synonym)|uniprotkb:Fatty acid ester hydrolase(gene name synonym)	psi-mi:cxcr2_human(display_long)|uniprotkb:CXCR2(gene name)|psi-mi:CXCR2(display_short)|uniprotkb:IL8RB(gene name synonym)|uniprotkb:CDw128b(gene name synonym)|uniprotkb:GRO/MGSA receptor(gene name synonym)|uniprotkb:High affinity interleukin-8 receptor B(gene name synonym)|uniprotkb:IL-8 receptor type 2(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274047|imex:IM-26901-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001432.2|go:"GO:0031090"(organelle membrane)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0052651"(monoacylglycerol catabolic process)|go:"GO:0102077"(oleamide hydrolase activity)|go:"GO:0103073"(anandamide amidohydrolase activity)|interpro:IPR020556|interpro:IPR023631|interpro:IPR030560|interpro:IPR036928|reactome:R-HSA-2142753|ensembl:ENSG00000117480(gene)|ensembl:ENST00000243167(transcript)|go:"GO:0004040"(amidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017064"(fatty acid amide hydrolase activity)|go:"GO:0019369"(arachidonic acid metabolic process)	ensembl:ENSG00000180871(gene)|ensembl:ENST00000318507(transcript)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0004918"(interleukin-8 receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|refseq:NP_001161770.1|refseq:NP_001548.1|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019959"(interleukin-8 binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0031623"(receptor internalization)|go:"GO:0033030"(negative regulation of neutrophil apoptotic process)|go:"GO:0038112"(interleukin-8-mediated signaling pathway)|go:"GO:0042119"(neutrophil activation)|go:"GO:0042629"(mast cell granule)|go:"GO:0043117"(positive regulation of vascular permeability)|refseq:XP_005246587.1|go:"GO:0060326"(cell chemotaxis)|go:"GO:0072173"(metanephric tubule morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|interpro:IPR000057(Interleukin 8B receptor)|interpro:IPR000174(Interleukin-8 receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|go:"GO:0045766"(positive regulation of angiogenesis)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:4Q3H|rcsb pdb:5TYT|rcsb pdb:6KVA|rcsb pdb:6KVF|rcsb pdb:6LFM|rcsb pdb:6LFO|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6798695|refseq:XP_016859479.1|refseq:XP_016859480.1|refseq:XP_016859481.1|dip:DIP-3782N	-	-	-	figure legend:Table 1-7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:VeMFlyWuJ+8wTUjTTWlcJ7GKPlg9606	rogid:T16V0LpaqMIhUJlknnqmSVxX39o9606	rigid:hBTSMo8fLTNXTN72SM8MEHOZ11E	false	-	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N2G8	uniprotkb:P32302	intact:EBI-10985637|uniprotkb:B4DQS4|uniprotkb:E9PDB5|uniprotkb:Q9BXM6|ensembl:ENSP00000301671|ensembl:ENSP00000467585	intact:EBI-2835269|uniprotkb:Q14811|ensembl:ENSP00000292174	psi-mi:ghdc_human(display_long)|uniprotkb:GHDC(gene name)|psi-mi:GHDC(display_short)|uniprotkb:D11LGP1E(gene name synonym)|uniprotkb:LGP1(gene name synonym)	psi-mi:cxcr5_human(display_long)|uniprotkb:CXCR5(gene name)|psi-mi:CXCR5(display_short)|uniprotkb:BLR1(gene name synonym)|uniprotkb:MDR15(gene name synonym)|uniprotkb:Burkitt lymphoma receptor 1(gene name synonym)|uniprotkb:Monocyte-derived receptor 15(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274058|imex:IM-26901-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001136095.1|refseq:NP_115873.1|ensembl:ENSG00000167925(gene)|ensembl:ENST00000301671(transcript)|ensembl:ENST00000587427(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016881"(acid-amino acid ligase activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035580"(specific granule lumen)|interpro:IPR004993(GH3 auxin-responsive promoter)|reactome:R-HSA-6798695	refseq:NP_001707.1|refseq:NP_116743.1|ensembl:ENSG00000160683(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0042113"(B cell activation)|go:"GO:0048535"(lymph node development)|go:"GO:0060326"(cell chemotaxis)|ensembl:ENST00000292174(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001053(C-X-C chemokine receptor, type 5)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-380108|reactome:R-HSA-418594|dip:DIP-5834N	-	-	-	figure legend:Table 1-9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:AlZkawSGl/YLF3onfXtqK0vWf4k9606	rogid:Sa+SeVlCfdW+E/5SOdYXaFoBgYU9606	rigid:MdFdWyyyxlGy+qyOjtNPEuu/wMY	false	-	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NEN9	uniprotkb:P47211	intact:EBI-4289868|uniprotkb:Q86WE5|uniprotkb:Q9UFF1|uniprotkb:Q86WE0|ensembl:ENSP00000334642	intact:EBI-6624741|ensembl:ENSP00000299727|uniprotkb:Q4VBL7	psi-mi:pdzd8_human(display_long)|uniprotkb:PDZD8(gene name)|psi-mi:PDZD8(display_short)|uniprotkb:PDZK8(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-84/NY-SAR-104(gene name synonym)	psi-mi:galr1_human(display_long)|uniprotkb:GALR1(gene name)|psi-mi:GALR1(display_short)|uniprotkb:GALNR(gene name synonym)|uniprotkb:GALNR1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274090|imex:IM-26901-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165650(gene)|ensembl:ENST00000334464(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR031468|interpro:IPR036034|interpro:IPR039275|interpro:IPR041489|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|refseq:NP_776152.1	ensembl:ENSG00000166573(gene)|ensembl:ENST00000299727(transcript)|go:"GO:0004966"(galanin receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051464"(positive regulation of cortisol secretion)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000405(Galanin receptor)|interpro:IPR003906(Galanin 1 receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-375276|reactome:R-HSA-418594|refseq:NP_001471.2	-	-	-	figure legend:Table 1-10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:J/uE/PwFeE+ZL58Qi2jAWaEf23s9606	rogid:2cyPncH8b79+lmM6piQTdEAS3h89606	rigid:ZNmwxA8Eetgm/TWA9pCcl6nZrs0	false	-	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NS75	uniprotkb:Q8IV08	intact:EBI-3843579|uniprotkb:Q9HCQ2|ensembl:ENSP00000282018|ensembl:ENSP00000477930|ensembl:ENSP00000508181	intact:EBI-2689908|uniprotkb:Q9BW87|uniprotkb:Q92853|ensembl:ENSP00000348901|ensembl:ENSP00000386293|ensembl:ENSP00000386938|ensembl:ENSP00000387022|ensembl:ENSP00000387050	psi-mi:cltr2_human(display_long)|uniprotkb:CYSLTR2(gene name)|psi-mi:CYSLTR2(display_short)|uniprotkb:CYSLT2(gene name synonym)|uniprotkb:CYSLT2R(gene name synonym)|uniprotkb:G-protein coupled receptor GPCR21(gene name synonym)|uniprotkb:G-protein coupled receptor HG57(gene name synonym)|uniprotkb:HPN321(gene name synonym)|uniprotkb:PSEC0146(orf name)	psi-mi:pld3_human(display_long)|uniprotkb:Choline phosphatase 3(gene name synonym)|uniprotkb:HindIII K4L homolog(gene name synonym)|uniprotkb:Hu-K4(gene name synonym)|uniprotkb:Phosphatidylcholine-hydrolyzing phospholipase D3(gene name synonym)|uniprotkb:Phospholipase D3(gene name synonym)|uniprotkb:PLD3(gene name)|psi-mi:PLD3(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274101|imex:IM-26901-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001295394.1|refseq:NP_001295396.1|refseq:NP_001295397.1|refseq:NP_001295398.1|refseq:NP_001295399.1|refseq:NP_001295400.1|refseq:NP_001295405.1|refseq:NP_065110.1|ensembl:ENSG00000152207(gene)|ensembl:ENST00000282018(transcript)|ensembl:ENST00000614739(transcript)|ensembl:ENST00000682523(transcript)|go:"GO:0001631"(cysteinyl leukotriene receptor activity)|go:"GO:0004974"(leukotriene receptor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0071377"(cellular response to glucagon stimulus)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR004071(Cysteinyl leukotriene receptor)|interpro:IPR013311(Cysteinyl leukotriene receptor 2)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:Q9NS75|reactome:R-HSA-163359|reactome:R-HSA-391906|reactome:R-HSA-416476|reactome:R-HSA-418555|reactome:R-HSA-420092|reactome:R-HSA-9660821|reactome:R-HSA-9664535	refseq:NP_001278240.1|refseq:XP_011524994.1|refseq:XP_011524995.1|refseq:NP_001026866.1|refseq:NP_036400.2|refseq:XP_005258761.1|refseq:XP_005258764.1|refseq:XP_005258765.1|refseq:XP_005258766.1|refseq:XP_005258767.1|ensembl:ENSG00000105223(gene)|ensembl:ENST00000356508(transcript)|ensembl:ENST00000409281(transcript)|ensembl:ENST00000409419(transcript)|ensembl:ENST00000409587(transcript)|ensembl:ENST00000409735(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002376"(immune system process)|go:"GO:0004630"(phospholipase D activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045145"(single-stranded DNA 5'-3' exodeoxyribonuclease activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|interpro:IPR032803|reactome:R-HSA-1483148|reactome:R-HSA-2029485|refseq:XP_006723185.1|refseq:XP_016882035.1|refseq:XP_016882036.1|refseq:XP_016882037.1|refseq:XP_016882038.1	-	-	-	figure legend:Table 1-11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:NRzlafGrSL5F5/uRRFJrMXrEsEc9606	rogid:UAnUtENnwfOxhcqSzMmb7yOlBFI9606	rigid:95Dpp6xU+2gHwSPDkuRtTxNq2pY	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NS75	uniprotkb:Q5T2T1	intact:EBI-3843579|uniprotkb:Q9HCQ2|ensembl:ENSP00000282018|ensembl:ENSP00000477930|ensembl:ENSP00000508181	intact:EBI-2514004|ensembl:ENSP00000337907|ensembl:ENSP00000364871|ensembl:ENSP00000364884|ensembl:ENSP00000507917|uniprotkb:B2RCC9|uniprotkb:Q5T2T0|uniprotkb:B5MDZ3|uniprotkb:Q8IY28|uniprotkb:B4DWL9|uniprotkb:D3DRW3	psi-mi:cltr2_human(display_long)|uniprotkb:CYSLTR2(gene name)|psi-mi:CYSLTR2(display_short)|uniprotkb:CYSLT2(gene name synonym)|uniprotkb:CYSLT2R(gene name synonym)|uniprotkb:G-protein coupled receptor GPCR21(gene name synonym)|uniprotkb:G-protein coupled receptor HG57(gene name synonym)|uniprotkb:HPN321(gene name synonym)|uniprotkb:PSEC0146(orf name)	psi-mi:mpp7_human(display_long)|uniprotkb:MPP7(gene name)|psi-mi:MPP7(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274101|imex:IM-26901-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001295394.1|refseq:NP_001295396.1|refseq:NP_001295397.1|refseq:NP_001295398.1|refseq:NP_001295399.1|refseq:NP_001295400.1|refseq:NP_001295405.1|refseq:NP_065110.1|ensembl:ENSG00000152207(gene)|ensembl:ENST00000282018(transcript)|ensembl:ENST00000614739(transcript)|ensembl:ENST00000682523(transcript)|go:"GO:0001631"(cysteinyl leukotriene receptor activity)|go:"GO:0004974"(leukotriene receptor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0071377"(cellular response to glucagon stimulus)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR004071(Cysteinyl leukotriene receptor)|interpro:IPR013311(Cysteinyl leukotriene receptor 2)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:Q9NS75|reactome:R-HSA-163359|reactome:R-HSA-391906|reactome:R-HSA-416476|reactome:R-HSA-418555|reactome:R-HSA-420092|reactome:R-HSA-9660821|reactome:R-HSA-9664535	ensembl:ENSG00000150054(gene)|ensembl:ENST00000337532(transcript)|ensembl:ENST00000375719(transcript)|ensembl:ENST00000375732(transcript)|ensembl:ENST00000683449(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071896"(protein localization to adherens junction)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR014775(L27, C-terminal)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035599|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q5T2T1|rcsb pdb:3LRA|rcsb pdb:3O46|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|reactome:R-HSA-9013409|reactome:R-HSA-9013423|refseq:XP_011517639.1|refseq:NP_001305099.1|refseq:NP_775767.2	-	-	-	figure legend:Table 1-11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:NRzlafGrSL5F5/uRRFJrMXrEsEc9606	rogid:QYVCkD5zsnTsCd7YsYsbQY8L7fU9606	rigid:95Dpp6xU+2gHwSPDkuRtTxNq2pY	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NS75	uniprotkb:Q9NUP9	intact:EBI-3843579|uniprotkb:Q9HCQ2|ensembl:ENSP00000282018|ensembl:ENSP00000477930|ensembl:ENSP00000508181	intact:EBI-1171517|ensembl:ENSP00000278193	psi-mi:cltr2_human(display_long)|uniprotkb:CYSLTR2(gene name)|psi-mi:CYSLTR2(display_short)|uniprotkb:CYSLT2(gene name synonym)|uniprotkb:CYSLT2R(gene name synonym)|uniprotkb:G-protein coupled receptor GPCR21(gene name synonym)|uniprotkb:G-protein coupled receptor HG57(gene name synonym)|uniprotkb:HPN321(gene name synonym)|uniprotkb:PSEC0146(orf name)	psi-mi:lin7c_human(display_long)|uniprotkb:Mammalian lin-seven protein 3(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 3(gene name synonym)|uniprotkb:LIN7C(gene name)|psi-mi:LIN7C(display_short)|uniprotkb:MALS3(gene name synonym)|uniprotkb:VELI3(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274101|imex:IM-26901-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001295394.1|refseq:NP_001295396.1|refseq:NP_001295397.1|refseq:NP_001295398.1|refseq:NP_001295399.1|refseq:NP_001295400.1|refseq:NP_001295405.1|refseq:NP_065110.1|ensembl:ENSG00000152207(gene)|ensembl:ENST00000282018(transcript)|ensembl:ENST00000614739(transcript)|ensembl:ENST00000682523(transcript)|go:"GO:0001631"(cysteinyl leukotriene receptor activity)|go:"GO:0004974"(leukotriene receptor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0071377"(cellular response to glucagon stimulus)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR004071(Cysteinyl leukotriene receptor)|interpro:IPR013311(Cysteinyl leukotriene receptor 2)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:Q9NS75|reactome:R-HSA-163359|reactome:R-HSA-391906|reactome:R-HSA-416476|reactome:R-HSA-418555|reactome:R-HSA-420092|reactome:R-HSA-9660821|reactome:R-HSA-9664535	refseq:NP_060832.1|ensembl:ENSG00000148943(gene)|ensembl:ENST00000278193(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|mint:Q9NUP9|rcsb pdb:3LRA|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736	-	-	-	figure legend:Table 1-11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:NRzlafGrSL5F5/uRRFJrMXrEsEc9606	rogid:F2rasaJ64Olc9qScN79LJRqsUEE9606	rigid:95Dpp6xU+2gHwSPDkuRtTxNq2pY	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NS75	uniprotkb:Q12959	intact:EBI-3843579|uniprotkb:Q9HCQ2|ensembl:ENSP00000282018|ensembl:ENSP00000477930|ensembl:ENSP00000508181	intact:EBI-357481|ensembl:ENSP00000391732|ensembl:ENSP00000407531|ensembl:ENSP00000499437|uniprotkb:Q12958|uniprotkb:A5YKK7|uniprotkb:B7ZMM0|uniprotkb:B9EIQ5|uniprotkb:D3DXB8|uniprotkb:D3DXB9|uniprotkb:B4DGU1|uniprotkb:B4DGZ8|uniprotkb:E7EWL7|uniprotkb:E9PG21	psi-mi:cltr2_human(display_long)|uniprotkb:CYSLTR2(gene name)|psi-mi:CYSLTR2(display_short)|uniprotkb:CYSLT2(gene name synonym)|uniprotkb:CYSLT2R(gene name synonym)|uniprotkb:G-protein coupled receptor GPCR21(gene name synonym)|uniprotkb:G-protein coupled receptor HG57(gene name synonym)|uniprotkb:HPN321(gene name synonym)|uniprotkb:PSEC0146(orf name)	psi-mi:dlg1_human(display_long)|uniprotkb:DLG1(gene name)|psi-mi:DLG1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:hDlg(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274101|imex:IM-26901-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001295394.1|refseq:NP_001295396.1|refseq:NP_001295397.1|refseq:NP_001295398.1|refseq:NP_001295399.1|refseq:NP_001295400.1|refseq:NP_001295405.1|refseq:NP_065110.1|ensembl:ENSG00000152207(gene)|ensembl:ENST00000282018(transcript)|ensembl:ENST00000614739(transcript)|ensembl:ENST00000682523(transcript)|go:"GO:0001631"(cysteinyl leukotriene receptor activity)|go:"GO:0004974"(leukotriene receptor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0071377"(cellular response to glucagon stimulus)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR004071(Cysteinyl leukotriene receptor)|interpro:IPR013311(Cysteinyl leukotriene receptor 2)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:Q9NS75|reactome:R-HSA-163359|reactome:R-HSA-391906|reactome:R-HSA-416476|reactome:R-HSA-418555|reactome:R-HSA-420092|reactome:R-HSA-9660821|reactome:R-HSA-9664535	reactome:R-HSA-9617324|reactome:R-HSA-9620244|ensembl:ENST00000419354(transcript)|ensembl:ENST00000448528(transcript)|ensembl:ENST00000670935(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|ensembl:ENSG00000075711(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0043113"(receptor clustering)|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|refseq:NP_001091894.1|refseq:NP_001191315.1|refseq:NP_001191316.1|refseq:NP_001191317.1|refseq:NP_004078.2|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030432"(peristalsis)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033268"(node of Ranvier)|go:"GO:0034629"|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|interpro:IPR019583|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q12959|rcsb pdb:1PDR|rcsb pdb:2M3M|rcsb pdb:2OQS|rcsb pdb:2X7Z|rcsb pdb:3LRA|rcsb pdb:3RL7|rcsb pdb:3RL8|rcsb pdb:3W9Y|rcsb pdb:4AMH|rcsb pdb:4G69|reactome:R-HSA-399719|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|reactome:R-HSA-438066|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|reactome:R-HSA-442982|reactome:R-HSA-447038|reactome:R-HSA-451308|reactome:R-HSA-5673001|reactome:R-HSA-8849932|reactome:R-HSA-9609736|refseq:XP_011510804.1|refseq:XP_011510807.1|refseq:XP_011510808.1|refseq:XP_005269346.1|refseq:NP_001277912.1|refseq:XP_016861289.1|refseq:XP_016861290.1|refseq:XP_016861291.1|refseq:XP_016861292.1|refseq:XP_016861294.1|refseq:XP_016861295.1|refseq:XP_016861296.1|refseq:XP_016861297.1|refseq:XP_016861298.1|refseq:XP_016861305.1|refseq:XP_016861306.1|refseq:XP_016861307.1|refseq:XP_016861308.1|refseq:XP_016861309.1|dip:DIP-33957N|refseq:XP_011510805.1|refseq:XP_016861299.1	-	-	-	figure legend:Table 1-11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:NRzlafGrSL5F5/uRRFJrMXrEsEc9606	rogid:ax5sUROdL8kF59RhocRWG6tUUkc9606	rigid:95Dpp6xU+2gHwSPDkuRtTxNq2pY	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NS75	uniprotkb:O14936	intact:EBI-3843579|uniprotkb:Q9HCQ2|ensembl:ENSP00000282018|ensembl:ENSP00000477930|ensembl:ENSP00000508181	intact:EBI-1215506|uniprotkb:Q5VT18|uniprotkb:Q5VT19|uniprotkb:Q66T42|uniprotkb:A6NES1|uniprotkb:O43215|uniprotkb:Q17RI4|uniprotkb:Q59HA0|uniprotkb:Q5VT16|uniprotkb:Q5VT17|uniprotkb:Q9BYH6|uniprotkb:Q9NYB2|uniprotkb:Q9NYB3|uniprotkb:B7ZKY0|ensembl:ENSP00000367405	psi-mi:cltr2_human(display_long)|uniprotkb:CYSLTR2(gene name)|psi-mi:CYSLTR2(display_short)|uniprotkb:CYSLT2(gene name synonym)|uniprotkb:CYSLT2R(gene name synonym)|uniprotkb:G-protein coupled receptor GPCR21(gene name synonym)|uniprotkb:G-protein coupled receptor HG57(gene name synonym)|uniprotkb:HPN321(gene name synonym)|uniprotkb:PSEC0146(orf name)	psi-mi:cskp_human(display_long)|uniprotkb:CASK(gene name)|psi-mi:CASK(display_short)|uniprotkb:LIN2(gene name synonym)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:Protein lin-2 homolog(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274101|imex:IM-26901-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001295394.1|refseq:NP_001295396.1|refseq:NP_001295397.1|refseq:NP_001295398.1|refseq:NP_001295399.1|refseq:NP_001295400.1|refseq:NP_001295405.1|refseq:NP_065110.1|ensembl:ENSG00000152207(gene)|ensembl:ENST00000282018(transcript)|ensembl:ENST00000614739(transcript)|ensembl:ENST00000682523(transcript)|go:"GO:0001631"(cysteinyl leukotriene receptor activity)|go:"GO:0004974"(leukotriene receptor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0071377"(cellular response to glucagon stimulus)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR004071(Cysteinyl leukotriene receptor)|interpro:IPR013311(Cysteinyl leukotriene receptor 2)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:Q9NS75|reactome:R-HSA-163359|reactome:R-HSA-391906|reactome:R-HSA-416476|reactome:R-HSA-418555|reactome:R-HSA-420092|reactome:R-HSA-9660821|reactome:R-HSA-9664535	refseq:NP_001119526.1|refseq:NP_001119527.1|refseq:NP_003679.2|dip:DIP-38727N|ensembl:ENSG00000147044(gene)|ensembl:ENST00000378163(transcript)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031982"(vesicle)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060170"(ciliary membrane)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070509"(calcium ion import)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|rcsb pdb:3MFT|rcsb pdb:3MFU|rcsb pdb:3TAC|rcsb pdb:6KMH|rcsb pdb:7OAI|rcsb pdb:7OAJ|rcsb pdb:7OAK|rcsb pdb:7OAL|reactome:R-HSA-212676|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-6794361|reactome:R-HSA-9609736|reactome:R-HSA-9662360|reactome:R-HSA-9662361|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014775(L27, C-terminal)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:O14936|rcsb pdb:1KGD|rcsb pdb:1KWA|rcsb pdb:1ZL8|rcsb pdb:3C0G|rcsb pdb:3C0H|rcsb pdb:3C0I|rcsb pdb:3MFR|rcsb pdb:3MFS	-	-	-	figure legend:Table 1-11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:NRzlafGrSL5F5/uRRFJrMXrEsEc9606	rogid:zTaBgQexJON3EVgJq9FHjf+aSCY9606	rigid:95Dpp6xU+2gHwSPDkuRtTxNq2pY	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04201	uniprotkb:Q9UPN7	intact:EBI-21274133|ensembl:ENSP00000252660|ensembl:ENSP00000501180|uniprotkb:E1P5B3|uniprotkb:Q2TBC9|uniprotkb:Q6FG47	intact:EBI-359745|uniprotkb:Q2M2H3|uniprotkb:Q504V2|uniprotkb:Q6NVJ6|uniprotkb:Q9BU97|intact:EBI-28973105|ensembl:ENSP00000414202|ensembl:ENSP00000467521	psi-mi:mas_human(display_long)|uniprotkb:MAS1(gene name)|psi-mi:MAS1(display_short)|uniprotkb:MAS(gene name synonym)	psi-mi:pp6r1_human(display_long)|uniprotkb:PPP6R1(gene name)|psi-mi:PPP6R1(display_short)|uniprotkb:KIAA1115(gene name synonym)|uniprotkb:PP6R1(gene name synonym)|uniprotkb:SAPS domain family member 1(gene name synonym)|uniprotkb:SAPS1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274119|imex:IM-26901-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0021766"(hippocampus development)|go:"GO:0034698"(response to gonadotropin)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060732"(positive regulation of inositol phosphate biosynthetic process)|go:"GO:0070528"(protein kinase C signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000820(Mas transmembrane protein)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR026234|go:"GO:0008584"(male gonad development)|ensembl:ENSG00000130368(gene)|ensembl:ENST00000252660(transcript)|ensembl:ENST00000674077(transcript)|go:"GO:0001595"(angiotensin receptor activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|refseq:NP_002368.1	refseq:NP_055746.3|ensembl:ENSP00000414202|ensembl:ENSP00000467521|ensembl:ENSG00000105063(gene)|ensembl:ENST00000412770(transcript)|ensembl:ENST00000587283(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q9UPN7|reactome:R-HSA-204005|dip:DIP-27589N	-	-	-	figure legend:Table 1-12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:jTpc5LGIES8MJjSm/jQQNwlF7n89606	rogid:Nab2lMgz1rQizyvjdbMrJUMNB+I9606	rigid:fDY4hJf8D7Y4xiLmalnNqQSWEBk	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04201	uniprotkb:Q12959	intact:EBI-21274133|ensembl:ENSP00000252660|ensembl:ENSP00000501180|uniprotkb:E1P5B3|uniprotkb:Q2TBC9|uniprotkb:Q6FG47	intact:EBI-357481|ensembl:ENSP00000391732|ensembl:ENSP00000407531|ensembl:ENSP00000499437|uniprotkb:Q12958|uniprotkb:A5YKK7|uniprotkb:B7ZMM0|uniprotkb:B9EIQ5|uniprotkb:D3DXB8|uniprotkb:D3DXB9|uniprotkb:B4DGU1|uniprotkb:B4DGZ8|uniprotkb:E7EWL7|uniprotkb:E9PG21	psi-mi:mas_human(display_long)|uniprotkb:MAS1(gene name)|psi-mi:MAS1(display_short)|uniprotkb:MAS(gene name synonym)	psi-mi:dlg1_human(display_long)|uniprotkb:DLG1(gene name)|psi-mi:DLG1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:hDlg(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274119|imex:IM-26901-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0021766"(hippocampus development)|go:"GO:0034698"(response to gonadotropin)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060732"(positive regulation of inositol phosphate biosynthetic process)|go:"GO:0070528"(protein kinase C signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000820(Mas transmembrane protein)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR026234|go:"GO:0008584"(male gonad development)|ensembl:ENSG00000130368(gene)|ensembl:ENST00000252660(transcript)|ensembl:ENST00000674077(transcript)|go:"GO:0001595"(angiotensin receptor activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|refseq:NP_002368.1	reactome:R-HSA-9617324|reactome:R-HSA-9620244|ensembl:ENST00000419354(transcript)|ensembl:ENST00000448528(transcript)|ensembl:ENST00000670935(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|ensembl:ENSG00000075711(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0043113"(receptor clustering)|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|refseq:NP_001091894.1|refseq:NP_001191315.1|refseq:NP_001191316.1|refseq:NP_001191317.1|refseq:NP_004078.2|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030432"(peristalsis)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033268"(node of Ranvier)|go:"GO:0034629"|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|interpro:IPR019583|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q12959|rcsb pdb:1PDR|rcsb pdb:2M3M|rcsb pdb:2OQS|rcsb pdb:2X7Z|rcsb pdb:3LRA|rcsb pdb:3RL7|rcsb pdb:3RL8|rcsb pdb:3W9Y|rcsb pdb:4AMH|rcsb pdb:4G69|reactome:R-HSA-399719|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|reactome:R-HSA-438066|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|reactome:R-HSA-442982|reactome:R-HSA-447038|reactome:R-HSA-451308|reactome:R-HSA-5673001|reactome:R-HSA-8849932|reactome:R-HSA-9609736|refseq:XP_011510804.1|refseq:XP_011510807.1|refseq:XP_011510808.1|refseq:XP_005269346.1|refseq:NP_001277912.1|refseq:XP_016861289.1|refseq:XP_016861290.1|refseq:XP_016861291.1|refseq:XP_016861292.1|refseq:XP_016861294.1|refseq:XP_016861295.1|refseq:XP_016861296.1|refseq:XP_016861297.1|refseq:XP_016861298.1|refseq:XP_016861305.1|refseq:XP_016861306.1|refseq:XP_016861307.1|refseq:XP_016861308.1|refseq:XP_016861309.1|dip:DIP-33957N|refseq:XP_011510805.1|refseq:XP_016861299.1	-	-	-	figure legend:Table 1-12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:jTpc5LGIES8MJjSm/jQQNwlF7n89606	rogid:ax5sUROdL8kF59RhocRWG6tUUkc9606	rigid:fDY4hJf8D7Y4xiLmalnNqQSWEBk	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04201	uniprotkb:O14936	intact:EBI-21274133|ensembl:ENSP00000252660|ensembl:ENSP00000501180|uniprotkb:E1P5B3|uniprotkb:Q2TBC9|uniprotkb:Q6FG47	intact:EBI-1215506|uniprotkb:Q5VT18|uniprotkb:Q5VT19|uniprotkb:Q66T42|uniprotkb:A6NES1|uniprotkb:O43215|uniprotkb:Q17RI4|uniprotkb:Q59HA0|uniprotkb:Q5VT16|uniprotkb:Q5VT17|uniprotkb:Q9BYH6|uniprotkb:Q9NYB2|uniprotkb:Q9NYB3|uniprotkb:B7ZKY0|ensembl:ENSP00000367405	psi-mi:mas_human(display_long)|uniprotkb:MAS1(gene name)|psi-mi:MAS1(display_short)|uniprotkb:MAS(gene name synonym)	psi-mi:cskp_human(display_long)|uniprotkb:CASK(gene name)|psi-mi:CASK(display_short)|uniprotkb:LIN2(gene name synonym)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:Protein lin-2 homolog(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274119|imex:IM-26901-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0021766"(hippocampus development)|go:"GO:0034698"(response to gonadotropin)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060732"(positive regulation of inositol phosphate biosynthetic process)|go:"GO:0070528"(protein kinase C signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000820(Mas transmembrane protein)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR026234|go:"GO:0008584"(male gonad development)|ensembl:ENSG00000130368(gene)|ensembl:ENST00000252660(transcript)|ensembl:ENST00000674077(transcript)|go:"GO:0001595"(angiotensin receptor activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|refseq:NP_002368.1	refseq:NP_001119526.1|refseq:NP_001119527.1|refseq:NP_003679.2|dip:DIP-38727N|ensembl:ENSG00000147044(gene)|ensembl:ENST00000378163(transcript)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031982"(vesicle)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060170"(ciliary membrane)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070509"(calcium ion import)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|rcsb pdb:3MFT|rcsb pdb:3MFU|rcsb pdb:3TAC|rcsb pdb:6KMH|rcsb pdb:7OAI|rcsb pdb:7OAJ|rcsb pdb:7OAK|rcsb pdb:7OAL|reactome:R-HSA-212676|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-6794361|reactome:R-HSA-9609736|reactome:R-HSA-9662360|reactome:R-HSA-9662361|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014775(L27, C-terminal)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:O14936|rcsb pdb:1KGD|rcsb pdb:1KWA|rcsb pdb:1ZL8|rcsb pdb:3C0G|rcsb pdb:3C0H|rcsb pdb:3C0I|rcsb pdb:3MFR|rcsb pdb:3MFS	-	-	-	figure legend:Table 1-12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:jTpc5LGIES8MJjSm/jQQNwlF7n89606	rogid:zTaBgQexJON3EVgJq9FHjf+aSCY9606	rigid:fDY4hJf8D7Y4xiLmalnNqQSWEBk	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14160	uniprotkb:P36873	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	intact:EBI-356283|ensembl:ENSP00000335084	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:pp1g_human(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277179|imex:IM-26901-56	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0004721"(phosphoprotein phosphatase activity)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0043197"(dendritic spine)|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|mint:P36873|rcsb pdb:1IT6|rcsb pdb:1JK7|rcsb pdb:1U32|rcsb pdb:2BCD|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|rcsb pdb:2BDX|rcsb pdb:4UT2|rcsb pdb:4UT3|go:"GO:0046872"(metal ion binding)|rcsb pdb:5INB|go:"GO:0047485"(protein N-terminus binding)|rcsb pdb:5J28|go:"GO:0051301"(cell division)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098793"(presynapse)|reactome:R-HSA-141444|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-9648025|reactome:R-HSA-9660537|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-400253|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-68877|refseq:NP_001231903.1|refseq:NP_002701.1|dip:DIP-749N	-	-	-	figure legend:Table 3-2|comment:Interaction in the presence of Wild Type ADRA1D.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606	rigid:MN93WoBSN7oKaT7/qwnlqLYxe5E	false	strep tag:n-n|calmodulin binding protein tag:n-n|ha tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14160	uniprotkb:Q9Y2X7	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	intact:EBI-466061|uniprotkb:Q86SS0|uniprotkb:Q9BRJ4|uniprotkb:B4DSV3|ensembl:ENSP00000225394|uniprotkb:B4DGU9	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:git1_human(display_long)|uniprotkb:GIT1(gene name)|psi-mi:GIT1(display_short)|uniprotkb:G protein-coupled receptor kinase-interactor 1(gene name synonym)|uniprotkb:GRK-interacting protein 1(gene name synonym)|uniprotkb:Cool-associated and tyrosine-phosphorylated protein 1(gene name synonym)|uniprotkb:p95-APP1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277179|imex:IM-26901-56	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	refseq:NP_001078923.1|refseq:NP_054749.2|ensembl:ENSG00000108262(gene)|ensembl:ENST00000225394(transcript)|go:"GO:0001957"(intramembranous ossification)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0044305"(calyx of Held)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045820"(negative regulation of glycolytic process)|interpro:IPR013724("Spa2 homology (SHD) of GIT")|go:"GO:0046872"(metal ion binding)|interpro:IPR020683|go:"GO:0048013"(ephrin receptor signaling pathway)|interpro:IPR022018|interpro:IPR032352|interpro:IPR036770|interpro:IPR037278|go:"GO:0048666"(neuron development)|go:"GO:0061743"(motor learning)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0106015"(negative regulation of inflammatory response to wounding)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR038508|interpro:IPR001164(Arf GTPase activating protein)|mint:Q9Y2X7|interpro:IPR002110(Ankyrin)|reactome:R-HSA-3928664|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9619229	-	-	-	figure legend:Table 3-2|comment:Interaction in the presence of Wild Type ADRA1D.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rogid:9POm+EVvD4/BQh6bApnpXCAZyZo9606	rigid:MN93WoBSN7oKaT7/qwnlqLYxe5E	false	strep tag:n-n|calmodulin binding protein tag:n-n|ha tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14160	uniprotkb:Q14155	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	intact:EBI-717515|uniprotkb:B1ALK6|uniprotkb:B1ALK8|uniprotkb:Q3LIA4|uniprotkb:Q5W9H0|uniprotkb:Q6P9G3|uniprotkb:Q6PII2|uniprotkb:Q86W63|uniprotkb:Q8N3M1|ensembl:ENSP00000364893	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:arhg7_human(display_long)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:COOL-1(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:Nbla10314(orf name)|uniprotkb:ARHGEF7(gene name)|psi-mi:ARHGEF7(display_short)|uniprotkb:COOL1(gene name synonym)|uniprotkb:KIAA0142(gene name synonym)|uniprotkb:P85SPR(gene name synonym)|uniprotkb:PAK3BP(gene name synonym)|uniprotkb:PIXB(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277179|imex:IM-26901-56	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	refseq:NP_001307782.1|refseq:NP_663788.1|refseq:NP_001106983.1|refseq:NP_001106984.1|refseq:NP_001106985.1|refseq:NP_001307780.1|refseq:NP_001307783.1|refseq:NP_001317526.1|refseq:NP_001317527.1|ensembl:ENSG00000102606(gene)|ensembl:ENST00000375741(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0005925"(focal adhesion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904424"(regulation of GTP binding)|go:"GO:1905833"(negative regulation of microtubule nucleation)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035789|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:Q14155|rcsb pdb:1BY1|rcsb pdb:1ZSG|rcsb pdb:2L3G|rcsb pdb:5SXP|reactome:R-HSA-182971|reactome:R-HSA-193648|reactome:R-HSA-3928664|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9619229|dip:DIP-40794N|refseq:NP_003890.1|refseq:XP_016876313.1|refseq:XP_016876314.1	-	-	-	figure legend:Table 3-2|comment:Interaction in the presence of Wild Type ADRA1D.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rogid:0I59YglGXcYP7fFKIAWM6uCZY8Q9606	rigid:MN93WoBSN7oKaT7/qwnlqLYxe5E	false	strep tag:n-n|calmodulin binding protein tag:n-n|ha tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14160	uniprotkb:Q15052	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	intact:EBI-1642523|uniprotkb:A6NMW9|uniprotkb:A8K6S7|uniprotkb:Q15396|uniprotkb:Q5JQ66|uniprotkb:Q7Z3W1|uniprotkb:Q86XH0|uniprotkb:B1AL37|ensembl:ENSP00000250617	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:arhg6_human(display_long)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277179|imex:IM-26901-56	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	refseq:NP_001293106.1|refseq:NP_004831.1|dip:DIP-42694N|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003096(SM22/calponin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR032409|interpro:IPR035788|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:Q15052|rcsb pdb:1UJY|rcsb pdb:1WYR|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-446388|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013420	-	-	-	figure legend:Table 3-2|comment:Interaction in the presence of Wild Type ADRA1D.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606	rigid:MN93WoBSN7oKaT7/qwnlqLYxe5E	false	strep tag:n-n|calmodulin binding protein tag:n-n|ha tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14160	uniprotkb:P46939	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40|ensembl:ENSP00000356515	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277179|imex:IM-26901-56	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	ensembl:ENSP00000356515|refseq:XP_011534408.1|refseq:NP_009055.2|refseq:XP_005267187.1|dip:DIP-711N|ensembl:ENSG00000152818(gene)|ensembl:ENST00000367545(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017166"(vinculin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665	-	-	-	figure legend:Table 3-2|comment:Interaction in the presence of Wild Type ADRA1D.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rogid:metWqbqGtzonNZ1mgNjlFrenuI89606	rigid:MN93WoBSN7oKaT7/qwnlqLYxe5E	false	strep tag:n-n|calmodulin binding protein tag:n-n|ha tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14160	uniprotkb:Q9Y4J8	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	intact:EBI-949471|ensembl:ENSP00000382064|uniprotkb:O15332|uniprotkb:O15333|uniprotkb:O75697|uniprotkb:Q13197|uniprotkb:Q13198|uniprotkb:Q13199|uniprotkb:Q13498|uniprotkb:Q13499|uniprotkb:Q13500|uniprotkb:A8MUY4|uniprotkb:A8K541|uniprotkb:M0QYX6|uniprotkb:A8MSZ0|uniprotkb:Q9BS59|uniprotkb:B4DIU8|uniprotkb:B4DIR0|uniprotkb:B4DGS6|uniprotkb:M0R397|uniprotkb:Q59GK7	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:dtna_human(display_long)|uniprotkb:Alpha-dystrobrevin(gene name synonym)|uniprotkb:Dystrophin-related protein 3(gene name synonym)|uniprotkb:DTNA(gene name)|psi-mi:DTNA(display_short)|uniprotkb:DRP3(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277179|imex:IM-26901-56	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	ensembl:ENSG00000134769(gene)|ensembl:ENST00000399113(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045202"(synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:Q9Y4J8|rcsb pdb:2E5R|interpro:IPR000433(Zinc finger, ZZ-type)|refseq:NP_001185873.1|refseq:NP_001381.2|refseq:NP_001382.2|refseq:NP_001383.2|refseq:NP_116757.2|refseq:NP_116760.2|refseq:NP_116761.2|refseq:NP_116762.2|refseq:NP_116763.1|refseq:XP_011524155.1|refseq:NP_001121647.1|refseq:NP_001185867.1|refseq:NP_001185868.1|refseq:NP_001185871.1|refseq:NP_001185869.1|refseq:NP_001185874.1|refseq:NP_001185870.1|refseq:XP_016881066.1|refseq:XP_016881073.1|refseq:XP_016881076.1|refseq:XP_016881077.1|refseq:XP_016881078.1|refseq:XP_016881079.1|refseq:XP_016881080.1|refseq:XP_016881089.1|refseq:XP_016881090.1|refseq:XP_016881091.1	-	-	-	figure legend:Table 3-2|comment:Interaction in the presence of Wild Type ADRA1D.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rogid:9HaDKLthoXmwdYDzbEer3CRN3O09606	rigid:MN93WoBSN7oKaT7/qwnlqLYxe5E	false	strep tag:n-n|calmodulin binding protein tag:n-n|ha tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14160	uniprotkb:P25100	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277179|imex:IM-26901-56	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	-	-	-	figure legend:Table 3-2|comment:Interaction in the presence of Wild Type ADRA1D.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rigid:MN93WoBSN7oKaT7/qwnlqLYxe5E	false	strep tag:n-n|calmodulin binding protein tag:n-n|ha tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14160	uniprotkb:Q13425	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	intact:EBI-80411|ensembl:ENSP00000338191|uniprotkb:Q9BY09	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:sntb2_human(display_long)|uniprotkb:SNT2B2(gene name synonym)|uniprotkb:SNTB2(gene name)|psi-mi:SNTB2(display_short)|uniprotkb:D16S2531E(gene name synonym)|uniprotkb:SNTL(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 2(gene name synonym)|uniprotkb:Syntrophin-3(gene name synonym)|uniprotkb:Syntrophin-like(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277179|imex:IM-26901-56	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0016020"(membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028550|interpro:IPR036034|interpro:IPR041428|mint:Q13425|rcsb pdb:2VRF|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000168807(gene)|ensembl:ENST00000336278(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_006741.1	-	-	-	figure legend:Table 3-2|comment:Interaction in the presence of Wild Type ADRA1D.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rogid:SABgmvArdLH93OpFobs/L3BleVY9606	rigid:MN93WoBSN7oKaT7/qwnlqLYxe5E	false	strep tag:n-n|calmodulin binding protein tag:n-n|ha tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14160	uniprotkb:P36873	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	intact:EBI-356283|ensembl:ENSP00000335084	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:pp1g_human(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277196|imex:IM-26901-58	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0004721"(phosphoprotein phosphatase activity)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0043197"(dendritic spine)|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|mint:P36873|rcsb pdb:1IT6|rcsb pdb:1JK7|rcsb pdb:1U32|rcsb pdb:2BCD|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|rcsb pdb:2BDX|rcsb pdb:4UT2|rcsb pdb:4UT3|go:"GO:0046872"(metal ion binding)|rcsb pdb:5INB|go:"GO:0047485"(protein N-terminus binding)|rcsb pdb:5J28|go:"GO:0051301"(cell division)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098793"(presynapse)|reactome:R-HSA-141444|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-9648025|reactome:R-HSA-9660537|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-400253|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-68877|refseq:NP_001231903.1|refseq:NP_002701.1|dip:DIP-749N	-	-	-	figure legend:Table 3-1|comment:Interaction in the absence of ADRA1D and in the presence of ADRA1D–DeltaPDZ.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/30	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606	rigid:X5vjmQg9pOAA5lxBvoFTC9NgFZI	false	strep tag:n-n|calmodulin binding protein tag:n-n|ha tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14160	uniprotkb:Q9Y2X7	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	intact:EBI-466061|uniprotkb:Q86SS0|uniprotkb:Q9BRJ4|uniprotkb:B4DSV3|ensembl:ENSP00000225394|uniprotkb:B4DGU9	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:git1_human(display_long)|uniprotkb:GIT1(gene name)|psi-mi:GIT1(display_short)|uniprotkb:G protein-coupled receptor kinase-interactor 1(gene name synonym)|uniprotkb:GRK-interacting protein 1(gene name synonym)|uniprotkb:Cool-associated and tyrosine-phosphorylated protein 1(gene name synonym)|uniprotkb:p95-APP1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277196|imex:IM-26901-58	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	refseq:NP_001078923.1|refseq:NP_054749.2|ensembl:ENSG00000108262(gene)|ensembl:ENST00000225394(transcript)|go:"GO:0001957"(intramembranous ossification)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0044305"(calyx of Held)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045820"(negative regulation of glycolytic process)|interpro:IPR013724("Spa2 homology (SHD) of GIT")|go:"GO:0046872"(metal ion binding)|interpro:IPR020683|go:"GO:0048013"(ephrin receptor signaling pathway)|interpro:IPR022018|interpro:IPR032352|interpro:IPR036770|interpro:IPR037278|go:"GO:0048666"(neuron development)|go:"GO:0061743"(motor learning)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0106015"(negative regulation of inflammatory response to wounding)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR038508|interpro:IPR001164(Arf GTPase activating protein)|mint:Q9Y2X7|interpro:IPR002110(Ankyrin)|reactome:R-HSA-3928664|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9619229	-	-	-	figure legend:Table 3-1|comment:Interaction in the absence of ADRA1D and in the presence of ADRA1D–DeltaPDZ.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/30	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rogid:9POm+EVvD4/BQh6bApnpXCAZyZo9606	rigid:X5vjmQg9pOAA5lxBvoFTC9NgFZI	false	strep tag:n-n|calmodulin binding protein tag:n-n|ha tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14160	uniprotkb:Q14155	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	intact:EBI-717515|uniprotkb:B1ALK6|uniprotkb:B1ALK8|uniprotkb:Q3LIA4|uniprotkb:Q5W9H0|uniprotkb:Q6P9G3|uniprotkb:Q6PII2|uniprotkb:Q86W63|uniprotkb:Q8N3M1|ensembl:ENSP00000364893	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:arhg7_human(display_long)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:COOL-1(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:Nbla10314(orf name)|uniprotkb:ARHGEF7(gene name)|psi-mi:ARHGEF7(display_short)|uniprotkb:COOL1(gene name synonym)|uniprotkb:KIAA0142(gene name synonym)|uniprotkb:P85SPR(gene name synonym)|uniprotkb:PAK3BP(gene name synonym)|uniprotkb:PIXB(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277196|imex:IM-26901-58	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	refseq:NP_001307782.1|refseq:NP_663788.1|refseq:NP_001106983.1|refseq:NP_001106984.1|refseq:NP_001106985.1|refseq:NP_001307780.1|refseq:NP_001307783.1|refseq:NP_001317526.1|refseq:NP_001317527.1|ensembl:ENSG00000102606(gene)|ensembl:ENST00000375741(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0005925"(focal adhesion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904424"(regulation of GTP binding)|go:"GO:1905833"(negative regulation of microtubule nucleation)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035789|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:Q14155|rcsb pdb:1BY1|rcsb pdb:1ZSG|rcsb pdb:2L3G|rcsb pdb:5SXP|reactome:R-HSA-182971|reactome:R-HSA-193648|reactome:R-HSA-3928664|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9619229|dip:DIP-40794N|refseq:NP_003890.1|refseq:XP_016876313.1|refseq:XP_016876314.1	-	-	-	figure legend:Table 3-1|comment:Interaction in the absence of ADRA1D and in the presence of ADRA1D–DeltaPDZ.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/30	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rogid:0I59YglGXcYP7fFKIAWM6uCZY8Q9606	rigid:X5vjmQg9pOAA5lxBvoFTC9NgFZI	false	strep tag:n-n|calmodulin binding protein tag:n-n|ha tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14160	uniprotkb:Q15052	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	intact:EBI-1642523|uniprotkb:A6NMW9|uniprotkb:A8K6S7|uniprotkb:Q15396|uniprotkb:Q5JQ66|uniprotkb:Q7Z3W1|uniprotkb:Q86XH0|uniprotkb:B1AL37|ensembl:ENSP00000250617	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:arhg6_human(display_long)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277196|imex:IM-26901-58	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	refseq:NP_001293106.1|refseq:NP_004831.1|dip:DIP-42694N|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003096(SM22/calponin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR032409|interpro:IPR035788|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:Q15052|rcsb pdb:1UJY|rcsb pdb:1WYR|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-446388|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013420	-	-	-	figure legend:Table 3-1|comment:Interaction in the absence of ADRA1D and in the presence of ADRA1D–DeltaPDZ.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/30	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606	rigid:X5vjmQg9pOAA5lxBvoFTC9NgFZI	false	strep tag:n-n|calmodulin binding protein tag:n-n|ha tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14160	uniprotkb:P46939	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40|ensembl:ENSP00000356515	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277240|imex:IM-26901-60	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	ensembl:ENSP00000356515|refseq:XP_011534408.1|refseq:NP_009055.2|refseq:XP_005267187.1|dip:DIP-711N|ensembl:ENSG00000152818(gene)|ensembl:ENST00000367545(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017166"(vinculin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665	-	-	-	figure legend:Table 3-3|comment:Interaction which requires the presence of PDZ ligand domain of ADRA1D.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rogid:metWqbqGtzonNZ1mgNjlFrenuI89606	rigid:m96ynW+5Y0LbFWtUKgoiNHDwsBk	false	strep tag:n-n|calmodulin binding protein tag:n-n|ha tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14160	uniprotkb:Q9Y4J8	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	intact:EBI-949471|ensembl:ENSP00000382064|uniprotkb:O15332|uniprotkb:O15333|uniprotkb:O75697|uniprotkb:Q13197|uniprotkb:Q13198|uniprotkb:Q13199|uniprotkb:Q13498|uniprotkb:Q13499|uniprotkb:Q13500|uniprotkb:A8MUY4|uniprotkb:A8K541|uniprotkb:M0QYX6|uniprotkb:A8MSZ0|uniprotkb:Q9BS59|uniprotkb:B4DIU8|uniprotkb:B4DIR0|uniprotkb:B4DGS6|uniprotkb:M0R397|uniprotkb:Q59GK7	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:dtna_human(display_long)|uniprotkb:Alpha-dystrobrevin(gene name synonym)|uniprotkb:Dystrophin-related protein 3(gene name synonym)|uniprotkb:DTNA(gene name)|psi-mi:DTNA(display_short)|uniprotkb:DRP3(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277240|imex:IM-26901-60	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	ensembl:ENSG00000134769(gene)|ensembl:ENST00000399113(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045202"(synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:Q9Y4J8|rcsb pdb:2E5R|interpro:IPR000433(Zinc finger, ZZ-type)|refseq:NP_001185873.1|refseq:NP_001381.2|refseq:NP_001382.2|refseq:NP_001383.2|refseq:NP_116757.2|refseq:NP_116760.2|refseq:NP_116761.2|refseq:NP_116762.2|refseq:NP_116763.1|refseq:XP_011524155.1|refseq:NP_001121647.1|refseq:NP_001185867.1|refseq:NP_001185868.1|refseq:NP_001185871.1|refseq:NP_001185869.1|refseq:NP_001185874.1|refseq:NP_001185870.1|refseq:XP_016881066.1|refseq:XP_016881073.1|refseq:XP_016881076.1|refseq:XP_016881077.1|refseq:XP_016881078.1|refseq:XP_016881079.1|refseq:XP_016881080.1|refseq:XP_016881089.1|refseq:XP_016881090.1|refseq:XP_016881091.1	-	-	-	figure legend:Table 3-3|comment:Interaction which requires the presence of PDZ ligand domain of ADRA1D.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rogid:9HaDKLthoXmwdYDzbEer3CRN3O09606	rigid:m96ynW+5Y0LbFWtUKgoiNHDwsBk	false	strep tag:n-n|calmodulin binding protein tag:n-n|ha tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14160	uniprotkb:P25100	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277240|imex:IM-26901-60	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	-	-	-	figure legend:Table 3-3|comment:Interaction which requires the presence of PDZ ligand domain of ADRA1D.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rigid:m96ynW+5Y0LbFWtUKgoiNHDwsBk	false	strep tag:n-n|calmodulin binding protein tag:n-n|ha tag:n-n	necessary binding region:569-572	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14160	uniprotkb:Q13425	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	intact:EBI-80411|ensembl:ENSP00000338191|uniprotkb:Q9BY09	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:sntb2_human(display_long)|uniprotkb:SNT2B2(gene name synonym)|uniprotkb:SNTB2(gene name)|psi-mi:SNTB2(display_short)|uniprotkb:D16S2531E(gene name synonym)|uniprotkb:SNTL(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 2(gene name synonym)|uniprotkb:Syntrophin-3(gene name synonym)|uniprotkb:Syntrophin-like(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277240|imex:IM-26901-60	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0016020"(membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028550|interpro:IPR036034|interpro:IPR041428|mint:Q13425|rcsb pdb:2VRF|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000168807(gene)|ensembl:ENST00000336278(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_006741.1	-	-	-	figure legend:Table 3-3|comment:Interaction which requires the presence of PDZ ligand domain of ADRA1D.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rogid:SABgmvArdLH93OpFobs/L3BleVY9606	rigid:m96ynW+5Y0LbFWtUKgoiNHDwsBk	false	strep tag:n-n|calmodulin binding protein tag:n-n|ha tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:P25100	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277288|imex:IM-26901-62	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	-	-	-	figure legend:Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rigid:/9sgnRZdAhmHeF/br8j8quvZ9+U	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n|sufficient binding region:1-568	myc tag:?-?	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:P46939	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40|ensembl:ENSP00000356515	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277288|imex:IM-26901-62	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	ensembl:ENSP00000356515|refseq:XP_011534408.1|refseq:NP_009055.2|refseq:XP_005267187.1|dip:DIP-711N|ensembl:ENSG00000152818(gene)|ensembl:ENST00000367545(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017166"(vinculin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665	-	-	-	figure legend:Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:metWqbqGtzonNZ1mgNjlFrenuI89606	rigid:/9sgnRZdAhmHeF/br8j8quvZ9+U	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n|sufficient binding region:1-568	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q9Y4J8	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-949471|ensembl:ENSP00000382064|uniprotkb:O15332|uniprotkb:O15333|uniprotkb:O75697|uniprotkb:Q13197|uniprotkb:Q13198|uniprotkb:Q13199|uniprotkb:Q13498|uniprotkb:Q13499|uniprotkb:Q13500|uniprotkb:A8MUY4|uniprotkb:A8K541|uniprotkb:M0QYX6|uniprotkb:A8MSZ0|uniprotkb:Q9BS59|uniprotkb:B4DIU8|uniprotkb:B4DIR0|uniprotkb:B4DGS6|uniprotkb:M0R397|uniprotkb:Q59GK7	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:dtna_human(display_long)|uniprotkb:Alpha-dystrobrevin(gene name synonym)|uniprotkb:Dystrophin-related protein 3(gene name synonym)|uniprotkb:DTNA(gene name)|psi-mi:DTNA(display_short)|uniprotkb:DRP3(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277288|imex:IM-26901-62	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	ensembl:ENSG00000134769(gene)|ensembl:ENST00000399113(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045202"(synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:Q9Y4J8|rcsb pdb:2E5R|interpro:IPR000433(Zinc finger, ZZ-type)|refseq:NP_001185873.1|refseq:NP_001381.2|refseq:NP_001382.2|refseq:NP_001383.2|refseq:NP_116757.2|refseq:NP_116760.2|refseq:NP_116761.2|refseq:NP_116762.2|refseq:NP_116763.1|refseq:XP_011524155.1|refseq:NP_001121647.1|refseq:NP_001185867.1|refseq:NP_001185868.1|refseq:NP_001185871.1|refseq:NP_001185869.1|refseq:NP_001185874.1|refseq:NP_001185870.1|refseq:XP_016881066.1|refseq:XP_016881073.1|refseq:XP_016881076.1|refseq:XP_016881077.1|refseq:XP_016881078.1|refseq:XP_016881079.1|refseq:XP_016881080.1|refseq:XP_016881089.1|refseq:XP_016881090.1|refseq:XP_016881091.1	-	-	-	figure legend:Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:9HaDKLthoXmwdYDzbEer3CRN3O09606	rigid:/9sgnRZdAhmHeF/br8j8quvZ9+U	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n|sufficient binding region:1-568	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:P11532	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-295827|uniprotkb:Q9UCW3|uniprotkb:Q9UCW4|uniprotkb:Q02295|uniprotkb:Q14169|uniprotkb:Q14170|uniprotkb:Q5JYU0|uniprotkb:Q7KZ48|intact:EBI-11041646|uniprotkb:A1L0U9|uniprotkb:Q8N754|uniprotkb:E9PDN1|uniprotkb:Q6NSJ9|intact:EBI-12189729|intact:EBI-22423597|intact:EBI-12702600|uniprotkb:E7EQR9|uniprotkb:E7EQS5|uniprotkb:E7ESB2|uniprotkb:E9PDN5|uniprotkb:F5GZY3|uniprotkb:F8VX32|intact:EBI-28985510	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:dmd_human(display_long)|uniprotkb:DMD(gene name)|psi-mi:DMD(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277288|imex:IM-26901-62	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_000100.2|refseq:NP_003997.1|refseq:NP_004000.1|refseq:NP_004001.1|refseq:NP_004002.2|refseq:NP_004003.1|refseq:NP_004004.1|refseq:NP_004005.1|refseq:NP_004008.1|refseq:NP_004009.1|refseq:NP_004010.1|refseq:NP_004011.2|refseq:NP_004012.1|refseq:NP_004013.1|refseq:NP_004014.1|refseq:NP_004006.1|refseq:NP_004007.1|ensembl:ENST00000682600|ensembl:ENSP00000507640|ensembl:ENST00000361471|ensembl:ENSP00000354464|ensembl:ENSG00000198947|ensembl:ENST00000378680|ensembl:ENSP00000367951|ensembl:ENST00000378702|ensembl:ENSP00000367974|ensembl:ENST00000378723|ensembl:ENSP00000367997|mint:P11532|dip:DIP-32593N|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009986"(cell surface)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|rcsb pdb:1DXX|rcsb pdb:1EG3|rcsb pdb:1EG4|rcsb pdb:3UUN|reactome:R-HSA-3000171|reactome:R-HSA-390522	-	-	-	figure legend:Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:gUFSTsQjsZpAmGI3+6ZPmUebofA9606	rigid:/9sgnRZdAhmHeF/br8j8quvZ9+U	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n|sufficient binding region:1-568	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q13425	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-80411|ensembl:ENSP00000338191|uniprotkb:Q9BY09	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:sntb2_human(display_long)|uniprotkb:SNT2B2(gene name synonym)|uniprotkb:SNTB2(gene name)|psi-mi:SNTB2(display_short)|uniprotkb:D16S2531E(gene name synonym)|uniprotkb:SNTL(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 2(gene name synonym)|uniprotkb:Syntrophin-3(gene name synonym)|uniprotkb:Syntrophin-like(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277288|imex:IM-26901-62	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0016020"(membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028550|interpro:IPR036034|interpro:IPR041428|mint:Q13425|rcsb pdb:2VRF|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000168807(gene)|ensembl:ENST00000336278(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_006741.1	-	-	-	figure legend:Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:SABgmvArdLH93OpFobs/L3BleVY9606	rigid:/9sgnRZdAhmHeF/br8j8quvZ9+U	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n|sufficient binding region:1-568	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q13884	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-295843|uniprotkb:O14912|uniprotkb:Q4KMG8|uniprotkb:A8K9E0|ensembl:ENSP00000378965|ensembl:ENSP00000431124	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:sntb1_human(display_long)|uniprotkb:SNTB1(gene name)|psi-mi:SNTB1(display_short)|uniprotkb:SNT2B1(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 1(gene name synonym)|uniprotkb:Tax interaction protein 43(gene name synonym)|uniprotkb:Syntrophin-2(gene name synonym)|uniprotkb:BSYN2(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277288|imex:IM-26901-62	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:XP_011515541.1|refseq:NP_066301.1|dip:DIP-466N|ensembl:ENSG00000172164(gene)|ensembl:ENST00000395601(transcript)|ensembl:ENST00000517992(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR036034|interpro:IPR041428|mint:Q13884	-	-	-	figure legend:Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:ysg02ZmUoj12kFHjpHE68vA1lUs9606	rigid:/9sgnRZdAhmHeF/br8j8quvZ9+U	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n|sufficient binding region:1-568	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:P46939	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40|ensembl:ENSP00000356515	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445595|imex:IM-26901-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	ensembl:ENSP00000356515|refseq:XP_011534408.1|refseq:NP_009055.2|refseq:XP_005267187.1|dip:DIP-711N|ensembl:ENSG00000152818(gene)|ensembl:ENST00000367545(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017166"(vinculin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665	-	-	-	figure legend:Table 4-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:metWqbqGtzonNZ1mgNjlFrenuI89606	rigid:BbBcAsVxWsy9pPPhmVyjqfr2l0c	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n|necessary binding region:569-572	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q9Y4J8	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-949471|ensembl:ENSP00000382064|uniprotkb:O15332|uniprotkb:O15333|uniprotkb:O75697|uniprotkb:Q13197|uniprotkb:Q13198|uniprotkb:Q13199|uniprotkb:Q13498|uniprotkb:Q13499|uniprotkb:Q13500|uniprotkb:A8MUY4|uniprotkb:A8K541|uniprotkb:M0QYX6|uniprotkb:A8MSZ0|uniprotkb:Q9BS59|uniprotkb:B4DIU8|uniprotkb:B4DIR0|uniprotkb:B4DGS6|uniprotkb:M0R397|uniprotkb:Q59GK7	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:dtna_human(display_long)|uniprotkb:Alpha-dystrobrevin(gene name synonym)|uniprotkb:Dystrophin-related protein 3(gene name synonym)|uniprotkb:DTNA(gene name)|psi-mi:DTNA(display_short)|uniprotkb:DRP3(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445595|imex:IM-26901-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	ensembl:ENSG00000134769(gene)|ensembl:ENST00000399113(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045202"(synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:Q9Y4J8|rcsb pdb:2E5R|interpro:IPR000433(Zinc finger, ZZ-type)|refseq:NP_001185873.1|refseq:NP_001381.2|refseq:NP_001382.2|refseq:NP_001383.2|refseq:NP_116757.2|refseq:NP_116760.2|refseq:NP_116761.2|refseq:NP_116762.2|refseq:NP_116763.1|refseq:XP_011524155.1|refseq:NP_001121647.1|refseq:NP_001185867.1|refseq:NP_001185868.1|refseq:NP_001185871.1|refseq:NP_001185869.1|refseq:NP_001185874.1|refseq:NP_001185870.1|refseq:XP_016881066.1|refseq:XP_016881073.1|refseq:XP_016881076.1|refseq:XP_016881077.1|refseq:XP_016881078.1|refseq:XP_016881079.1|refseq:XP_016881080.1|refseq:XP_016881089.1|refseq:XP_016881090.1|refseq:XP_016881091.1	-	-	-	figure legend:Table 4-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:9HaDKLthoXmwdYDzbEer3CRN3O09606	rigid:BbBcAsVxWsy9pPPhmVyjqfr2l0c	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n|necessary binding region:569-572	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:P11532	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-295827|uniprotkb:Q9UCW3|uniprotkb:Q9UCW4|uniprotkb:Q02295|uniprotkb:Q14169|uniprotkb:Q14170|uniprotkb:Q5JYU0|uniprotkb:Q7KZ48|intact:EBI-11041646|uniprotkb:A1L0U9|uniprotkb:Q8N754|uniprotkb:E9PDN1|uniprotkb:Q6NSJ9|intact:EBI-12189729|intact:EBI-22423597|intact:EBI-12702600|uniprotkb:E7EQR9|uniprotkb:E7EQS5|uniprotkb:E7ESB2|uniprotkb:E9PDN5|uniprotkb:F5GZY3|uniprotkb:F8VX32|intact:EBI-28985510	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:dmd_human(display_long)|uniprotkb:DMD(gene name)|psi-mi:DMD(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445595|imex:IM-26901-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_000100.2|refseq:NP_003997.1|refseq:NP_004000.1|refseq:NP_004001.1|refseq:NP_004002.2|refseq:NP_004003.1|refseq:NP_004004.1|refseq:NP_004005.1|refseq:NP_004008.1|refseq:NP_004009.1|refseq:NP_004010.1|refseq:NP_004011.2|refseq:NP_004012.1|refseq:NP_004013.1|refseq:NP_004014.1|refseq:NP_004006.1|refseq:NP_004007.1|ensembl:ENST00000682600|ensembl:ENSP00000507640|ensembl:ENST00000361471|ensembl:ENSP00000354464|ensembl:ENSG00000198947|ensembl:ENST00000378680|ensembl:ENSP00000367951|ensembl:ENST00000378702|ensembl:ENSP00000367974|ensembl:ENST00000378723|ensembl:ENSP00000367997|mint:P11532|dip:DIP-32593N|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009986"(cell surface)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|rcsb pdb:1DXX|rcsb pdb:1EG3|rcsb pdb:1EG4|rcsb pdb:3UUN|reactome:R-HSA-3000171|reactome:R-HSA-390522	-	-	-	figure legend:Table 4-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:gUFSTsQjsZpAmGI3+6ZPmUebofA9606	rigid:BbBcAsVxWsy9pPPhmVyjqfr2l0c	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n|necessary binding region:569-572	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q9UBT7	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-514206|uniprotkb:O76084|uniprotkb:Q53FQ2|uniprotkb:Q5JTQ7|uniprotkb:Q5JTQ8|uniprotkb:Q9Y401|uniprotkb:B5BU47|ensembl:ENSP00000320434	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:ctnl1_human(display_long)|uniprotkb:Catenin alpha-like protein 1(gene name synonym)|uniprotkb:Alpha-catenin-related protein(gene name synonym)|uniprotkb:CTNNAL1(gene name)|psi-mi:CTNNAL1(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445595|imex:IM-26901-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_003789.1|refseq:NP_001273903.1|dip:DIP-33236N|ensembl:ENSG00000119326(gene)|ensembl:ENST00000325551(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030045|interpro:IPR036723|mint:Q9UBT7	-	-	-	figure legend:Table 4-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:4XpDxeBmUk7NAT/aAAhl0c8Sc1w9606	rigid:BbBcAsVxWsy9pPPhmVyjqfr2l0c	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n|necessary binding region:569-572	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q13425	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-80411|ensembl:ENSP00000338191|uniprotkb:Q9BY09	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:sntb2_human(display_long)|uniprotkb:SNT2B2(gene name synonym)|uniprotkb:SNTB2(gene name)|psi-mi:SNTB2(display_short)|uniprotkb:D16S2531E(gene name synonym)|uniprotkb:SNTL(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 2(gene name synonym)|uniprotkb:Syntrophin-3(gene name synonym)|uniprotkb:Syntrophin-like(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445595|imex:IM-26901-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0016020"(membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028550|interpro:IPR036034|interpro:IPR041428|mint:Q13425|rcsb pdb:2VRF|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000168807(gene)|ensembl:ENST00000336278(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_006741.1	-	-	-	figure legend:Table 4-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:SABgmvArdLH93OpFobs/L3BleVY9606	rigid:BbBcAsVxWsy9pPPhmVyjqfr2l0c	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n|necessary binding region:569-572	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q13884	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-295843|uniprotkb:O14912|uniprotkb:Q4KMG8|uniprotkb:A8K9E0|ensembl:ENSP00000378965|ensembl:ENSP00000431124	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:sntb1_human(display_long)|uniprotkb:SNTB1(gene name)|psi-mi:SNTB1(display_short)|uniprotkb:SNT2B1(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 1(gene name synonym)|uniprotkb:Tax interaction protein 43(gene name synonym)|uniprotkb:Syntrophin-2(gene name synonym)|uniprotkb:BSYN2(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445595|imex:IM-26901-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:XP_011515541.1|refseq:NP_066301.1|dip:DIP-466N|ensembl:ENSG00000172164(gene)|ensembl:ENST00000395601(transcript)|ensembl:ENST00000517992(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR036034|interpro:IPR041428|mint:Q13884	-	-	-	figure legend:Table 4-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:ysg02ZmUoj12kFHjpHE68vA1lUs9606	rigid:BbBcAsVxWsy9pPPhmVyjqfr2l0c	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n|necessary binding region:569-572	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q14160	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445595|imex:IM-26901-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:Table 4-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rigid:BbBcAsVxWsy9pPPhmVyjqfr2l0c	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n|necessary binding region:569-572	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q14160	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274192|imex:IM-26901-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:Figure 1A Lane 3|comment:"ADRA1D interacted with both endogenous and ectopic SCRIB (Figure 1a, lanes 2 and 3). In Lane 4 CLIP tagged SCRIB may  be present as well as endogenous SCRIB.  ADRA1D is mostly expressed as homodimers or higher-order oligomers."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rigid:QkLS3h8ag2Z13TQvo3S6HPt0KGs	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P25100	uniprotkb:Q14160	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274192|imex:IM-26901-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:Figure 1A Lane 3|comment:"ADRA1D interacted with both endogenous and ectopic SCRIB (Figure 1a, lanes 2 and 3). In Lane 4 CLIP tagged SCRIB may  be present as well as endogenous SCRIB.  ADRA1D is mostly expressed as homodimers or higher-order oligomers."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rigid:QkLS3h8ag2Z13TQvo3S6HPt0KGs	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14160	uniprotkb:P25100	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274237|imex:IM-26901-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	-	-	-	figure legend:Figure 1C-Lane 1, Fig 1A lane 2, Figure 3B Lane 4, Figure 2A/B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rigid:QkLS3h8ag2Z13TQvo3S6HPt0KGs	false	-	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n|necessary binding region:569-572	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P25100	uniprotkb:Q13424	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-717191|intact:EBI-28985258|ensembl:ENSP00000217381|uniprotkb:Q16438|uniprotkb:A8K7H9|uniprotkb:E1P5N1|uniprotkb:B4DX40	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:snta1_human(display_long)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)|uniprotkb:SNTA1(gene name)|psi-mi:SNTA1(display_short)|uniprotkb:SNT1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274253|imex:IM-26901-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	ensembl:ENSG00000101400(gene)|ensembl:ENST00000217381(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|refseq:NP_003089.1|ensembl:ENSP00000217381|go:"GO:0042383"(sarcolemma)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|dip:DIP-966N	-	-	-	figure legend:Figure 1C-Lane 2, Figure 2 A/B|comment:"Overexpressing SNTA competes away SCRIB:ADRA1D binding (lane 2)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:ZeVEy6ZeNSJx2vwfHg0WaEu80OE9606	rigid:39PNf4RdFxsw7p/rmZtSJCd6wjA	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P25100	uniprotkb:Q14160	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274253|imex:IM-26901-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:Figure 1C-Lane 2, Figure 2 A/B|comment:"Overexpressing SNTA competes away SCRIB:ADRA1D binding (lane 2)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rigid:39PNf4RdFxsw7p/rmZtSJCd6wjA	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P25100	uniprotkb:Q13424	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-717191|intact:EBI-28985258|ensembl:ENSP00000217381|uniprotkb:Q16438|uniprotkb:A8K7H9|uniprotkb:E1P5N1|uniprotkb:B4DX40	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:snta1_human(display_long)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)|uniprotkb:SNTA1(gene name)|psi-mi:SNTA1(display_short)|uniprotkb:SNT1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274265|imex:IM-26901-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	ensembl:ENSG00000101400(gene)|ensembl:ENST00000217381(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|refseq:NP_003089.1|ensembl:ENSP00000217381|go:"GO:0042383"(sarcolemma)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|dip:DIP-966N	-	-	-	figure legend:Figure 1C-Lane 4|comment:"Co-overexpressing SNTA and SCRIB substantially diminishes SCRIB:ADRA1D binding (lane 4)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:ZeVEy6ZeNSJx2vwfHg0WaEu80OE9606	rigid:39PNf4RdFxsw7p/rmZtSJCd6wjA	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P25100	uniprotkb:Q14160	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274265|imex:IM-26901-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:Figure 1C-Lane 4|comment:"Co-overexpressing SNTA and SCRIB substantially diminishes SCRIB:ADRA1D binding (lane 4)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rigid:39PNf4RdFxsw7p/rmZtSJCd6wjA	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14160	uniprotkb:P25100	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274277|imex:IM-26901-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	-	-	-	figure legend:Figure 1C-Lane 3|comment:"Lane 3: over expressed SCRIB alone."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rigid:QkLS3h8ag2Z13TQvo3S6HPt0KGs	false	-	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P25100	uniprotkb:P25100	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277072|imex:IM-26901-39	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	-	-	-	figure legend:Figure 3A/B Lane 2|comment:Myc–ADRA1D was mainly detected at M.Wt >140kDa- in multimers.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rigid:QkLS3h8ag2Z13TQvo3S6HPt0KGs	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P25100	uniprotkb:Q14160	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277072|imex:IM-26901-39	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:Figure 3A/B Lane 2|comment:Myc–ADRA1D was mainly detected at M.Wt >140kDa- in multimers.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rigid:QkLS3h8ag2Z13TQvo3S6HPt0KGs	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13424	uniprotkb:P25100	intact:EBI-717191|intact:EBI-28985258|ensembl:ENSP00000217381|uniprotkb:Q16438|uniprotkb:A8K7H9|uniprotkb:E1P5N1|uniprotkb:B4DX40	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	psi-mi:snta1_human(display_long)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)|uniprotkb:SNTA1(gene name)|psi-mi:SNTA1(display_short)|uniprotkb:SNT1(gene name synonym)	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277087|imex:IM-26901-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101400(gene)|ensembl:ENST00000217381(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|refseq:NP_003089.1|ensembl:ENSP00000217381|go:"GO:0042383"(sarcolemma)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|dip:DIP-966N	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	-	-	-	figure legend:Figure 3A Lane 4|comment:A SNTA-ADRA1D complex can recruit SCRIB  Myc–ADRA1D was mainly detected at M.Wt >140kDa- in multimers.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/28	rogid:ZeVEy6ZeNSJx2vwfHg0WaEu80OE9606	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rigid:39PNf4RdFxsw7p/rmZtSJCd6wjA	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13424	uniprotkb:Q14160	intact:EBI-717191|intact:EBI-28985258|ensembl:ENSP00000217381|uniprotkb:Q16438|uniprotkb:A8K7H9|uniprotkb:E1P5N1|uniprotkb:B4DX40	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	psi-mi:snta1_human(display_long)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)|uniprotkb:SNTA1(gene name)|psi-mi:SNTA1(display_short)|uniprotkb:SNT1(gene name synonym)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277087|imex:IM-26901-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101400(gene)|ensembl:ENST00000217381(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|refseq:NP_003089.1|ensembl:ENSP00000217381|go:"GO:0042383"(sarcolemma)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|dip:DIP-966N	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:Figure 3A Lane 4|comment:A SNTA-ADRA1D complex can recruit SCRIB  Myc–ADRA1D was mainly detected at M.Wt >140kDa- in multimers.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/28	rogid:ZeVEy6ZeNSJx2vwfHg0WaEu80OE9606	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rigid:39PNf4RdFxsw7p/rmZtSJCd6wjA	false	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P25100	uniprotkb:P25100	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21277103|imex:IM-26901-53	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	-	-	-	figure legend:Figure 3B Lane 5|comment:Myc–ADRA1D was mainly detected at M.Wt >140kDa- in multimers.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/19	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rigid:c5JSGrdtgc+MEtxwUXqJxzRyUdY	false	myc tag:?-?	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n|sufficient binding region:1-568	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13424	uniprotkb:P25100	intact:EBI-717191|intact:EBI-28985258|ensembl:ENSP00000217381|uniprotkb:Q16438|uniprotkb:A8K7H9|uniprotkb:E1P5N1|uniprotkb:B4DX40	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	psi-mi:snta1_human(display_long)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)|uniprotkb:SNTA1(gene name)|psi-mi:SNTA1(display_short)|uniprotkb:SNT1(gene name synonym)	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445776|imex:IM-26901-66	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101400(gene)|ensembl:ENST00000217381(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|refseq:NP_003089.1|ensembl:ENSP00000217381|go:"GO:0042383"(sarcolemma)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|dip:DIP-966N	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	-	-	-	figure legend:Figure 1C-Lane 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/05/30	rogid:ZeVEy6ZeNSJx2vwfHg0WaEu80OE9606	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rigid:tqv6xR3Zz2Aq54XxNIvVL1J5+aE	false	-	strep tag:n-n|ha tag:n-n|calmodulin binding protein tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P25100	uniprotkb:Q14160	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274211|imex:IM-26901-45	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	go:"GO:0005886"(plasma membrane)	-	-	figure legend:Figure 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rigid:39PNf4RdFxsw7p/rmZtSJCd6wjA	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P25100	uniprotkb:Q13424	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-717191|intact:EBI-28985258|ensembl:ENSP00000217381|uniprotkb:Q16438|uniprotkb:A8K7H9|uniprotkb:E1P5N1|uniprotkb:B4DX40	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:snta1_human(display_long)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)|uniprotkb:SNTA1(gene name)|psi-mi:SNTA1(display_short)|uniprotkb:SNT1(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274211|imex:IM-26901-45	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	ensembl:ENSG00000101400(gene)|ensembl:ENST00000217381(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|refseq:NP_003089.1|ensembl:ENSP00000217381|go:"GO:0042383"(sarcolemma)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|dip:DIP-966N	go:"GO:0005886"(plasma membrane)	-	-	figure legend:Figure 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:ZeVEy6ZeNSJx2vwfHg0WaEu80OE9606	rigid:39PNf4RdFxsw7p/rmZtSJCd6wjA	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P25100	uniprotkb:O60941	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-740402|intact:EBI-784159|uniprotkb:O43782|uniprotkb:O60881|ensembl:ENSP00000384084|uniprotkb:O75538|uniprotkb:Q96AW0|uniprotkb:Q9UE14|uniprotkb:Q9UE15|uniprotkb:Q9UE16|uniprotkb:G5E9F6|uniprotkb:Q86VR4|uniprotkb:B7Z733|uniprotkb:F5GZG4	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:dtnb_human(display_long)|uniprotkb:DTNB(gene name)|psi-mi:DTNB(display_short)|uniprotkb:Beta-dystrobrevin(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274379|imex:IM-26901-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_001243232.1|refseq:NP_068707.1|refseq:NP_149159.2|refseq:NP_149160.1|refseq:NP_899204.1|ensembl:ENSG00000138101(gene)|ensembl:ENST00000406818(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0045202"(synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:O60941|refseq:NP_001243237.1|refseq:NP_899205.1|refseq:NP_001307861.1|refseq:NP_001307862.1|refseq:NP_001307863.1|refseq:NP_001307864.1|refseq:NP_001307865.1	-	-	-	figure legend:Table 2-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:/yB9vgxJOii2Uk4riTNLOhf9gUk9606	rigid:uFZfV+sM3A0ZfWleal2wo+doq58	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:P46939	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40|ensembl:ENSP00000356515	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274379|imex:IM-26901-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	ensembl:ENSP00000356515|refseq:XP_011534408.1|refseq:NP_009055.2|refseq:XP_005267187.1|dip:DIP-711N|ensembl:ENSG00000152818(gene)|ensembl:ENST00000367545(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017166"(vinculin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665	-	-	-	figure legend:Table 2-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:metWqbqGtzonNZ1mgNjlFrenuI89606	rigid:uFZfV+sM3A0ZfWleal2wo+doq58	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q9Y4J8	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-949471|ensembl:ENSP00000382064|uniprotkb:O15332|uniprotkb:O15333|uniprotkb:O75697|uniprotkb:Q13197|uniprotkb:Q13198|uniprotkb:Q13199|uniprotkb:Q13498|uniprotkb:Q13499|uniprotkb:Q13500|uniprotkb:A8MUY4|uniprotkb:A8K541|uniprotkb:M0QYX6|uniprotkb:A8MSZ0|uniprotkb:Q9BS59|uniprotkb:B4DIU8|uniprotkb:B4DIR0|uniprotkb:B4DGS6|uniprotkb:M0R397|uniprotkb:Q59GK7	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:dtna_human(display_long)|uniprotkb:Alpha-dystrobrevin(gene name synonym)|uniprotkb:Dystrophin-related protein 3(gene name synonym)|uniprotkb:DTNA(gene name)|psi-mi:DTNA(display_short)|uniprotkb:DRP3(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274379|imex:IM-26901-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	ensembl:ENSG00000134769(gene)|ensembl:ENST00000399113(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045202"(synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:Q9Y4J8|rcsb pdb:2E5R|interpro:IPR000433(Zinc finger, ZZ-type)|refseq:NP_001185873.1|refseq:NP_001381.2|refseq:NP_001382.2|refseq:NP_001383.2|refseq:NP_116757.2|refseq:NP_116760.2|refseq:NP_116761.2|refseq:NP_116762.2|refseq:NP_116763.1|refseq:XP_011524155.1|refseq:NP_001121647.1|refseq:NP_001185867.1|refseq:NP_001185868.1|refseq:NP_001185871.1|refseq:NP_001185869.1|refseq:NP_001185874.1|refseq:NP_001185870.1|refseq:XP_016881066.1|refseq:XP_016881073.1|refseq:XP_016881076.1|refseq:XP_016881077.1|refseq:XP_016881078.1|refseq:XP_016881079.1|refseq:XP_016881080.1|refseq:XP_016881089.1|refseq:XP_016881090.1|refseq:XP_016881091.1	-	-	-	figure legend:Table 2-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:9HaDKLthoXmwdYDzbEer3CRN3O09606	rigid:uFZfV+sM3A0ZfWleal2wo+doq58	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q13424	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-717191|intact:EBI-28985258|ensembl:ENSP00000217381|uniprotkb:Q16438|uniprotkb:A8K7H9|uniprotkb:E1P5N1|uniprotkb:B4DX40	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:snta1_human(display_long)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)|uniprotkb:SNTA1(gene name)|psi-mi:SNTA1(display_short)|uniprotkb:SNT1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274379|imex:IM-26901-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	ensembl:ENSG00000101400(gene)|ensembl:ENST00000217381(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|refseq:NP_003089.1|ensembl:ENSP00000217381|go:"GO:0042383"(sarcolemma)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|dip:DIP-966N	-	-	-	figure legend:Table 2-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:ZeVEy6ZeNSJx2vwfHg0WaEu80OE9606	rigid:uFZfV+sM3A0ZfWleal2wo+doq58	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q9UBT7	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-514206|uniprotkb:O76084|uniprotkb:Q53FQ2|uniprotkb:Q5JTQ7|uniprotkb:Q5JTQ8|uniprotkb:Q9Y401|uniprotkb:B5BU47|ensembl:ENSP00000320434	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:ctnl1_human(display_long)|uniprotkb:Catenin alpha-like protein 1(gene name synonym)|uniprotkb:Alpha-catenin-related protein(gene name synonym)|uniprotkb:CTNNAL1(gene name)|psi-mi:CTNNAL1(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274379|imex:IM-26901-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_003789.1|refseq:NP_001273903.1|dip:DIP-33236N|ensembl:ENSG00000119326(gene)|ensembl:ENST00000325551(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030045|interpro:IPR036723|mint:Q9UBT7	-	-	-	figure legend:Table 2-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:4XpDxeBmUk7NAT/aAAhl0c8Sc1w9606	rigid:uFZfV+sM3A0ZfWleal2wo+doq58	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q13425	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-80411|ensembl:ENSP00000338191|uniprotkb:Q9BY09	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:sntb2_human(display_long)|uniprotkb:SNT2B2(gene name synonym)|uniprotkb:SNTB2(gene name)|psi-mi:SNTB2(display_short)|uniprotkb:D16S2531E(gene name synonym)|uniprotkb:SNTL(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 2(gene name synonym)|uniprotkb:Syntrophin-3(gene name synonym)|uniprotkb:Syntrophin-like(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274379|imex:IM-26901-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0016020"(membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028550|interpro:IPR036034|interpro:IPR041428|mint:Q13425|rcsb pdb:2VRF|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000168807(gene)|ensembl:ENST00000336278(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_006741.1	-	-	-	figure legend:Table 2-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:SABgmvArdLH93OpFobs/L3BleVY9606	rigid:uFZfV+sM3A0ZfWleal2wo+doq58	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q13884	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-295843|uniprotkb:O14912|uniprotkb:Q4KMG8|uniprotkb:A8K9E0|ensembl:ENSP00000378965|ensembl:ENSP00000431124	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:sntb1_human(display_long)|uniprotkb:SNTB1(gene name)|psi-mi:SNTB1(display_short)|uniprotkb:SNT2B1(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 1(gene name synonym)|uniprotkb:Tax interaction protein 43(gene name synonym)|uniprotkb:Syntrophin-2(gene name synonym)|uniprotkb:BSYN2(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274379|imex:IM-26901-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:XP_011515541.1|refseq:NP_066301.1|dip:DIP-466N|ensembl:ENSG00000172164(gene)|ensembl:ENST00000395601(transcript)|ensembl:ENST00000517992(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR036034|interpro:IPR041428|mint:Q13884	-	-	-	figure legend:Table 2-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:ysg02ZmUoj12kFHjpHE68vA1lUs9606	rigid:uFZfV+sM3A0ZfWleal2wo+doq58	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q14160	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274379|imex:IM-26901-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:Table 2-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rigid:uFZfV+sM3A0ZfWleal2wo+doq58	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:P28482	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-959949|ensembl:ENSP00000215832|ensembl:ENSP00000381803|uniprotkb:A8CZ64	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:mk01_human(display_long)|uniprotkb:MAPK1(gene name)|psi-mi:MAPK1(display_short)|uniprotkb:ERK2(gene name synonym)|uniprotkb:PRKM1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)|uniprotkb:PRKM2(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274395|imex:IM-26901-35	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	reactome:R-HSA-112411|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-437239|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|refseq:NP_002736.3|refseq:NP_620407.1|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019858"(cytosine metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030424"(axon)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035094"(response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043627"(response to estrogen)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P28482|rcsb pdb:1PME|go:"GO:0072686"(mitotic spindle)|rcsb pdb:1TVO|rcsb pdb:1WZY|rcsb pdb:2OJG|rcsb pdb:2OJI|rcsb pdb:2OJJ|rcsb pdb:2Y9Q|rcsb pdb:3D42|rcsb pdb:3D44|rcsb pdb:3I5Z|rcsb pdb:3I60|rcsb pdb:3SA0|rcsb pdb:3TEI|rcsb pdb:3W55|rcsb pdb:4FMQ|rcsb pdb:4FUX|rcsb pdb:4FUY|rcsb pdb:4FV0|rcsb pdb:4FV1|rcsb pdb:4FV2|rcsb pdb:4FV3|rcsb pdb:4FV4|rcsb pdb:4FV5|rcsb pdb:4FV6|rcsb pdb:4FV7|rcsb pdb:4FV8|rcsb pdb:4FV9|rcsb pdb:4G6N|rcsb pdb:4G6O|rcsb pdb:4H3P|rcsb pdb:4H3Q|rcsb pdb:4IZ5|rcsb pdb:4IZ7|rcsb pdb:4IZA|rcsb pdb:4N0S|rcsb pdb:4NIF|rcsb pdb:4O6E|rcsb pdb:4QP1|rcsb pdb:4QP2|rcsb pdb:4QP3|rcsb pdb:4QP4|rcsb pdb:4QP6|rcsb pdb:4QP7|rcsb pdb:4QP8|rcsb pdb:4QP9|rcsb pdb:4QPA|rcsb pdb:4QTA|rcsb pdb:4QTE|rcsb pdb:4XJ0|rcsb pdb:4ZXT|rcsb pdb:4ZZM|rcsb pdb:4ZZN|rcsb pdb:4ZZO|rcsb pdb:5AX3|rcsb pdb:5BUE|rcsb pdb:5BUI|rcsb pdb:5BUJ|rcsb pdb:5BVD|rcsb pdb:5BVE|rcsb pdb:5BVF|rcsb pdb:5K4I|rcsb pdb:5LCJ|rcsb pdb:5LCK|rcsb pdb:5NGU|rcsb pdb:5NHF|rcsb pdb:5NHH|rcsb pdb:5NHJ|rcsb pdb:5NHL|rcsb pdb:5NHO|rcsb pdb:5NHP|rcsb pdb:5NHV|rcsb pdb:5V60|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:5WP1|rcsb pdb:6D5Y|rcsb pdb:6DMG|rcsb pdb:6G54|rcsb pdb:6G8X|rcsb pdb:6G91|rcsb pdb:6G92|rcsb pdb:6G93|rcsb pdb:6G97|rcsb pdb:6G9A|rcsb pdb:6G9D|rcsb pdb:6G9H|rcsb pdb:6G9J|rcsb pdb:6G9K|rcsb pdb:6G9M|rcsb pdb:6G9N|rcsb pdb:6GDM|rcsb pdb:6GDQ|rcsb pdb:6GE0|rcsb pdb:6GJB|rcsb pdb:6GJD|rcsb pdb:6NBS|rcsb pdb:6OPG|rcsb pdb:6OPH|rcsb pdb:6OPI|rcsb pdb:6Q7K|rcsb pdb:6Q7S|rcsb pdb:6Q7T|rcsb pdb:6QA1|rcsb pdb:6QA3|rcsb pdb:6QA4|rcsb pdb:6QAG|rcsb pdb:6QAH|rcsb pdb:6QAL|rcsb pdb:6QAQ|rcsb pdb:6QAW|rcsb pdb:6RQ4|rcsb pdb:6SLG|reactome:R-HSA-111995|reactome:R-HSA-112409|ensembl:ENSG00000100030(gene)|ensembl:ENST00000215832(transcript)|ensembl:ENST00000398822(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634635|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9652817|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|dip:DIP-519N|ensembl:ENSP00000215832|ensembl:ENSP00000381803|ensembl:ENST00000544786|ensembl:ENSP00000440842	-	-	-	figure legend:Table 2-3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:odzhd70I/8uWedx0+gF38lhe60I9606	rigid:k+msdtcgqClfoQWQoFhRm9LGpPY	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:P46939	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40|ensembl:ENSP00000356515	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274395|imex:IM-26901-35	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	ensembl:ENSP00000356515|refseq:XP_011534408.1|refseq:NP_009055.2|refseq:XP_005267187.1|dip:DIP-711N|ensembl:ENSG00000152818(gene)|ensembl:ENST00000367545(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017166"(vinculin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665	-	-	-	figure legend:Table 2-3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:metWqbqGtzonNZ1mgNjlFrenuI89606	rigid:k+msdtcgqClfoQWQoFhRm9LGpPY	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:O60941	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-740402|intact:EBI-784159|uniprotkb:O43782|uniprotkb:O60881|ensembl:ENSP00000384084|uniprotkb:O75538|uniprotkb:Q96AW0|uniprotkb:Q9UE14|uniprotkb:Q9UE15|uniprotkb:Q9UE16|uniprotkb:G5E9F6|uniprotkb:Q86VR4|uniprotkb:B7Z733|uniprotkb:F5GZG4	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:dtnb_human(display_long)|uniprotkb:DTNB(gene name)|psi-mi:DTNB(display_short)|uniprotkb:Beta-dystrobrevin(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274395|imex:IM-26901-35	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_001243232.1|refseq:NP_068707.1|refseq:NP_149159.2|refseq:NP_149160.1|refseq:NP_899204.1|ensembl:ENSG00000138101(gene)|ensembl:ENST00000406818(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0045202"(synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:O60941|refseq:NP_001243237.1|refseq:NP_899205.1|refseq:NP_001307861.1|refseq:NP_001307862.1|refseq:NP_001307863.1|refseq:NP_001307864.1|refseq:NP_001307865.1	-	-	-	figure legend:Table 2-3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:/yB9vgxJOii2Uk4riTNLOhf9gUk9606	rigid:k+msdtcgqClfoQWQoFhRm9LGpPY	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:P11532	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-295827|uniprotkb:Q9UCW3|uniprotkb:Q9UCW4|uniprotkb:Q02295|uniprotkb:Q14169|uniprotkb:Q14170|uniprotkb:Q5JYU0|uniprotkb:Q7KZ48|intact:EBI-11041646|uniprotkb:A1L0U9|uniprotkb:Q8N754|uniprotkb:E9PDN1|uniprotkb:Q6NSJ9|intact:EBI-12189729|intact:EBI-22423597|intact:EBI-12702600|uniprotkb:E7EQR9|uniprotkb:E7EQS5|uniprotkb:E7ESB2|uniprotkb:E9PDN5|uniprotkb:F5GZY3|uniprotkb:F8VX32|intact:EBI-28985510	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:dmd_human(display_long)|uniprotkb:DMD(gene name)|psi-mi:DMD(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274395|imex:IM-26901-35	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_000100.2|refseq:NP_003997.1|refseq:NP_004000.1|refseq:NP_004001.1|refseq:NP_004002.2|refseq:NP_004003.1|refseq:NP_004004.1|refseq:NP_004005.1|refseq:NP_004008.1|refseq:NP_004009.1|refseq:NP_004010.1|refseq:NP_004011.2|refseq:NP_004012.1|refseq:NP_004013.1|refseq:NP_004014.1|refseq:NP_004006.1|refseq:NP_004007.1|ensembl:ENST00000682600|ensembl:ENSP00000507640|ensembl:ENST00000361471|ensembl:ENSP00000354464|ensembl:ENSG00000198947|ensembl:ENST00000378680|ensembl:ENSP00000367951|ensembl:ENST00000378702|ensembl:ENSP00000367974|ensembl:ENST00000378723|ensembl:ENSP00000367997|mint:P11532|dip:DIP-32593N|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009986"(cell surface)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|rcsb pdb:1DXX|rcsb pdb:1EG3|rcsb pdb:1EG4|rcsb pdb:3UUN|reactome:R-HSA-3000171|reactome:R-HSA-390522	-	-	-	figure legend:Table 2-3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:gUFSTsQjsZpAmGI3+6ZPmUebofA9606	rigid:k+msdtcgqClfoQWQoFhRm9LGpPY	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q13425	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-80411|ensembl:ENSP00000338191|uniprotkb:Q9BY09	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:sntb2_human(display_long)|uniprotkb:SNT2B2(gene name synonym)|uniprotkb:SNTB2(gene name)|psi-mi:SNTB2(display_short)|uniprotkb:D16S2531E(gene name synonym)|uniprotkb:SNTL(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 2(gene name synonym)|uniprotkb:Syntrophin-3(gene name synonym)|uniprotkb:Syntrophin-like(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274395|imex:IM-26901-35	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0016020"(membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028550|interpro:IPR036034|interpro:IPR041428|mint:Q13425|rcsb pdb:2VRF|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000168807(gene)|ensembl:ENST00000336278(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_006741.1	-	-	-	figure legend:Table 2-3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:SABgmvArdLH93OpFobs/L3BleVY9606	rigid:k+msdtcgqClfoQWQoFhRm9LGpPY	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q14160	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274395|imex:IM-26901-35	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:Table 2-3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rigid:k+msdtcgqClfoQWQoFhRm9LGpPY	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:P46939	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40|ensembl:ENSP00000356515	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274411|imex:IM-26901-37	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	ensembl:ENSP00000356515|refseq:XP_011534408.1|refseq:NP_009055.2|refseq:XP_005267187.1|dip:DIP-711N|ensembl:ENSG00000152818(gene)|ensembl:ENST00000367545(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017166"(vinculin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665	-	-	-	figure legend:Table 2-4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:metWqbqGtzonNZ1mgNjlFrenuI89606	rigid:4ureEG2/f+J3NXpOVWvGi4VRcOc	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q9Y4J8	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-949471|ensembl:ENSP00000382064|uniprotkb:O15332|uniprotkb:O15333|uniprotkb:O75697|uniprotkb:Q13197|uniprotkb:Q13198|uniprotkb:Q13199|uniprotkb:Q13498|uniprotkb:Q13499|uniprotkb:Q13500|uniprotkb:A8MUY4|uniprotkb:A8K541|uniprotkb:M0QYX6|uniprotkb:A8MSZ0|uniprotkb:Q9BS59|uniprotkb:B4DIU8|uniprotkb:B4DIR0|uniprotkb:B4DGS6|uniprotkb:M0R397|uniprotkb:Q59GK7	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:dtna_human(display_long)|uniprotkb:Alpha-dystrobrevin(gene name synonym)|uniprotkb:Dystrophin-related protein 3(gene name synonym)|uniprotkb:DTNA(gene name)|psi-mi:DTNA(display_short)|uniprotkb:DRP3(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274411|imex:IM-26901-37	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	ensembl:ENSG00000134769(gene)|ensembl:ENST00000399113(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045202"(synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:Q9Y4J8|rcsb pdb:2E5R|interpro:IPR000433(Zinc finger, ZZ-type)|refseq:NP_001185873.1|refseq:NP_001381.2|refseq:NP_001382.2|refseq:NP_001383.2|refseq:NP_116757.2|refseq:NP_116760.2|refseq:NP_116761.2|refseq:NP_116762.2|refseq:NP_116763.1|refseq:XP_011524155.1|refseq:NP_001121647.1|refseq:NP_001185867.1|refseq:NP_001185868.1|refseq:NP_001185871.1|refseq:NP_001185869.1|refseq:NP_001185874.1|refseq:NP_001185870.1|refseq:XP_016881066.1|refseq:XP_016881073.1|refseq:XP_016881076.1|refseq:XP_016881077.1|refseq:XP_016881078.1|refseq:XP_016881079.1|refseq:XP_016881080.1|refseq:XP_016881089.1|refseq:XP_016881090.1|refseq:XP_016881091.1	-	-	-	figure legend:Table 2-4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:9HaDKLthoXmwdYDzbEer3CRN3O09606	rigid:4ureEG2/f+J3NXpOVWvGi4VRcOc	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:P11532	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-295827|uniprotkb:Q9UCW3|uniprotkb:Q9UCW4|uniprotkb:Q02295|uniprotkb:Q14169|uniprotkb:Q14170|uniprotkb:Q5JYU0|uniprotkb:Q7KZ48|intact:EBI-11041646|uniprotkb:A1L0U9|uniprotkb:Q8N754|uniprotkb:E9PDN1|uniprotkb:Q6NSJ9|intact:EBI-12189729|intact:EBI-22423597|intact:EBI-12702600|uniprotkb:E7EQR9|uniprotkb:E7EQS5|uniprotkb:E7ESB2|uniprotkb:E9PDN5|uniprotkb:F5GZY3|uniprotkb:F8VX32|intact:EBI-28985510	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:dmd_human(display_long)|uniprotkb:DMD(gene name)|psi-mi:DMD(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274411|imex:IM-26901-37	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_000100.2|refseq:NP_003997.1|refseq:NP_004000.1|refseq:NP_004001.1|refseq:NP_004002.2|refseq:NP_004003.1|refseq:NP_004004.1|refseq:NP_004005.1|refseq:NP_004008.1|refseq:NP_004009.1|refseq:NP_004010.1|refseq:NP_004011.2|refseq:NP_004012.1|refseq:NP_004013.1|refseq:NP_004014.1|refseq:NP_004006.1|refseq:NP_004007.1|ensembl:ENST00000682600|ensembl:ENSP00000507640|ensembl:ENST00000361471|ensembl:ENSP00000354464|ensembl:ENSG00000198947|ensembl:ENST00000378680|ensembl:ENSP00000367951|ensembl:ENST00000378702|ensembl:ENSP00000367974|ensembl:ENST00000378723|ensembl:ENSP00000367997|mint:P11532|dip:DIP-32593N|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009986"(cell surface)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|rcsb pdb:1DXX|rcsb pdb:1EG3|rcsb pdb:1EG4|rcsb pdb:3UUN|reactome:R-HSA-3000171|reactome:R-HSA-390522	-	-	-	figure legend:Table 2-4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:gUFSTsQjsZpAmGI3+6ZPmUebofA9606	rigid:4ureEG2/f+J3NXpOVWvGi4VRcOc	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q13425	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-80411|ensembl:ENSP00000338191|uniprotkb:Q9BY09	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:sntb2_human(display_long)|uniprotkb:SNT2B2(gene name synonym)|uniprotkb:SNTB2(gene name)|psi-mi:SNTB2(display_short)|uniprotkb:D16S2531E(gene name synonym)|uniprotkb:SNTL(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 2(gene name synonym)|uniprotkb:Syntrophin-3(gene name synonym)|uniprotkb:Syntrophin-like(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274411|imex:IM-26901-37	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0016020"(membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028550|interpro:IPR036034|interpro:IPR041428|mint:Q13425|rcsb pdb:2VRF|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000168807(gene)|ensembl:ENST00000336278(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_006741.1	-	-	-	figure legend:Table 2-4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:SABgmvArdLH93OpFobs/L3BleVY9606	rigid:4ureEG2/f+J3NXpOVWvGi4VRcOc	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:P28482	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-959949|ensembl:ENSP00000215832|ensembl:ENSP00000381803|uniprotkb:A8CZ64	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:mk01_human(display_long)|uniprotkb:MAPK1(gene name)|psi-mi:MAPK1(display_short)|uniprotkb:ERK2(gene name synonym)|uniprotkb:PRKM1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)|uniprotkb:PRKM2(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274411|imex:IM-26901-37	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	reactome:R-HSA-112411|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-437239|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|refseq:NP_002736.3|refseq:NP_620407.1|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019858"(cytosine metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030424"(axon)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035094"(response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043627"(response to estrogen)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P28482|rcsb pdb:1PME|go:"GO:0072686"(mitotic spindle)|rcsb pdb:1TVO|rcsb pdb:1WZY|rcsb pdb:2OJG|rcsb pdb:2OJI|rcsb pdb:2OJJ|rcsb pdb:2Y9Q|rcsb pdb:3D42|rcsb pdb:3D44|rcsb pdb:3I5Z|rcsb pdb:3I60|rcsb pdb:3SA0|rcsb pdb:3TEI|rcsb pdb:3W55|rcsb pdb:4FMQ|rcsb pdb:4FUX|rcsb pdb:4FUY|rcsb pdb:4FV0|rcsb pdb:4FV1|rcsb pdb:4FV2|rcsb pdb:4FV3|rcsb pdb:4FV4|rcsb pdb:4FV5|rcsb pdb:4FV6|rcsb pdb:4FV7|rcsb pdb:4FV8|rcsb pdb:4FV9|rcsb pdb:4G6N|rcsb pdb:4G6O|rcsb pdb:4H3P|rcsb pdb:4H3Q|rcsb pdb:4IZ5|rcsb pdb:4IZ7|rcsb pdb:4IZA|rcsb pdb:4N0S|rcsb pdb:4NIF|rcsb pdb:4O6E|rcsb pdb:4QP1|rcsb pdb:4QP2|rcsb pdb:4QP3|rcsb pdb:4QP4|rcsb pdb:4QP6|rcsb pdb:4QP7|rcsb pdb:4QP8|rcsb pdb:4QP9|rcsb pdb:4QPA|rcsb pdb:4QTA|rcsb pdb:4QTE|rcsb pdb:4XJ0|rcsb pdb:4ZXT|rcsb pdb:4ZZM|rcsb pdb:4ZZN|rcsb pdb:4ZZO|rcsb pdb:5AX3|rcsb pdb:5BUE|rcsb pdb:5BUI|rcsb pdb:5BUJ|rcsb pdb:5BVD|rcsb pdb:5BVE|rcsb pdb:5BVF|rcsb pdb:5K4I|rcsb pdb:5LCJ|rcsb pdb:5LCK|rcsb pdb:5NGU|rcsb pdb:5NHF|rcsb pdb:5NHH|rcsb pdb:5NHJ|rcsb pdb:5NHL|rcsb pdb:5NHO|rcsb pdb:5NHP|rcsb pdb:5NHV|rcsb pdb:5V60|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:5WP1|rcsb pdb:6D5Y|rcsb pdb:6DMG|rcsb pdb:6G54|rcsb pdb:6G8X|rcsb pdb:6G91|rcsb pdb:6G92|rcsb pdb:6G93|rcsb pdb:6G97|rcsb pdb:6G9A|rcsb pdb:6G9D|rcsb pdb:6G9H|rcsb pdb:6G9J|rcsb pdb:6G9K|rcsb pdb:6G9M|rcsb pdb:6G9N|rcsb pdb:6GDM|rcsb pdb:6GDQ|rcsb pdb:6GE0|rcsb pdb:6GJB|rcsb pdb:6GJD|rcsb pdb:6NBS|rcsb pdb:6OPG|rcsb pdb:6OPH|rcsb pdb:6OPI|rcsb pdb:6Q7K|rcsb pdb:6Q7S|rcsb pdb:6Q7T|rcsb pdb:6QA1|rcsb pdb:6QA3|rcsb pdb:6QA4|rcsb pdb:6QAG|rcsb pdb:6QAH|rcsb pdb:6QAL|rcsb pdb:6QAQ|rcsb pdb:6QAW|rcsb pdb:6RQ4|rcsb pdb:6SLG|reactome:R-HSA-111995|reactome:R-HSA-112409|ensembl:ENSG00000100030(gene)|ensembl:ENST00000215832(transcript)|ensembl:ENST00000398822(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634635|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9652817|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|dip:DIP-519N|ensembl:ENSP00000215832|ensembl:ENSP00000381803|ensembl:ENST00000544786|ensembl:ENSP00000440842	-	-	-	figure legend:Table 2-4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:odzhd70I/8uWedx0+gF38lhe60I9606	rigid:4ureEG2/f+J3NXpOVWvGi4VRcOc	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q14160	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274411|imex:IM-26901-37	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:Table 2-4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rigid:4ureEG2/f+J3NXpOVWvGi4VRcOc	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:P27361	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-73995|uniprotkb:B0LPG3|uniprotkb:A8CZ58|uniprotkb:Q8NHX1|ensembl:ENSP00000263025	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:mk03_human(display_long)|uniprotkb:ERT2(gene name synonym)|uniprotkb:MAP kinase isoform p44(gene name synonym)|uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym)|uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym)|uniprotkb:p44-ERK1(gene name synonym)|uniprotkb:MAPK3(gene name)|psi-mi:MAPK3(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:PRKM3(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274411|imex:IM-26901-37	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_001035145.1|refseq:NP_001103361.1|refseq:NP_002737.2|dip:DIP-30985N|ensembl:ENSG00000102882(gene)|ensembl:ENST00000263025(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000657"(negative regulation of apolipoprotein binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P27361|rcsb pdb:2ZOQ|rcsb pdb:4QTB|rcsb pdb:6GES|reactome:R-HSA-110056|reactome:R-HSA-112409|reactome:R-HSA-1169408|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-73728|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)	-	-	-	figure legend:Table 2-4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:PGxmRMz0kOsJTfdn21FBiF33YwI9606	rigid:4ureEG2/f+J3NXpOVWvGi4VRcOc	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:O60941	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-740402|intact:EBI-784159|uniprotkb:O43782|uniprotkb:O60881|ensembl:ENSP00000384084|uniprotkb:O75538|uniprotkb:Q96AW0|uniprotkb:Q9UE14|uniprotkb:Q9UE15|uniprotkb:Q9UE16|uniprotkb:G5E9F6|uniprotkb:Q86VR4|uniprotkb:B7Z733|uniprotkb:F5GZG4	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:dtnb_human(display_long)|uniprotkb:DTNB(gene name)|psi-mi:DTNB(display_short)|uniprotkb:Beta-dystrobrevin(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274411|imex:IM-26901-37	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_001243232.1|refseq:NP_068707.1|refseq:NP_149159.2|refseq:NP_149160.1|refseq:NP_899204.1|ensembl:ENSG00000138101(gene)|ensembl:ENST00000406818(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0045202"(synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:O60941|refseq:NP_001243237.1|refseq:NP_899205.1|refseq:NP_001307861.1|refseq:NP_001307862.1|refseq:NP_001307863.1|refseq:NP_001307864.1|refseq:NP_001307865.1	-	-	-	figure legend:Table 2-4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:/yB9vgxJOii2Uk4riTNLOhf9gUk9606	rigid:4ureEG2/f+J3NXpOVWvGi4VRcOc	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:P46939	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40|ensembl:ENSP00000356515	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274427|imex:IM-26901-49	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	ensembl:ENSP00000356515|refseq:XP_011534408.1|refseq:NP_009055.2|refseq:XP_005267187.1|dip:DIP-711N|ensembl:ENSG00000152818(gene)|ensembl:ENST00000367545(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017166"(vinculin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665	-	-	-	figure legend:Table 2-5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a375)|taxid:9606(Human malignant melanoma)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:metWqbqGtzonNZ1mgNjlFrenuI89606	rigid:nRynYDe2+ccEzGbL8U+2dXgHwBI	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q9Y4J8	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-949471|ensembl:ENSP00000382064|uniprotkb:O15332|uniprotkb:O15333|uniprotkb:O75697|uniprotkb:Q13197|uniprotkb:Q13198|uniprotkb:Q13199|uniprotkb:Q13498|uniprotkb:Q13499|uniprotkb:Q13500|uniprotkb:A8MUY4|uniprotkb:A8K541|uniprotkb:M0QYX6|uniprotkb:A8MSZ0|uniprotkb:Q9BS59|uniprotkb:B4DIU8|uniprotkb:B4DIR0|uniprotkb:B4DGS6|uniprotkb:M0R397|uniprotkb:Q59GK7	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:dtna_human(display_long)|uniprotkb:Alpha-dystrobrevin(gene name synonym)|uniprotkb:Dystrophin-related protein 3(gene name synonym)|uniprotkb:DTNA(gene name)|psi-mi:DTNA(display_short)|uniprotkb:DRP3(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274427|imex:IM-26901-49	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	ensembl:ENSG00000134769(gene)|ensembl:ENST00000399113(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045202"(synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:Q9Y4J8|rcsb pdb:2E5R|interpro:IPR000433(Zinc finger, ZZ-type)|refseq:NP_001185873.1|refseq:NP_001381.2|refseq:NP_001382.2|refseq:NP_001383.2|refseq:NP_116757.2|refseq:NP_116760.2|refseq:NP_116761.2|refseq:NP_116762.2|refseq:NP_116763.1|refseq:XP_011524155.1|refseq:NP_001121647.1|refseq:NP_001185867.1|refseq:NP_001185868.1|refseq:NP_001185871.1|refseq:NP_001185869.1|refseq:NP_001185874.1|refseq:NP_001185870.1|refseq:XP_016881066.1|refseq:XP_016881073.1|refseq:XP_016881076.1|refseq:XP_016881077.1|refseq:XP_016881078.1|refseq:XP_016881079.1|refseq:XP_016881080.1|refseq:XP_016881089.1|refseq:XP_016881090.1|refseq:XP_016881091.1	-	-	-	figure legend:Table 2-5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a375)|taxid:9606(Human malignant melanoma)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:9HaDKLthoXmwdYDzbEer3CRN3O09606	rigid:nRynYDe2+ccEzGbL8U+2dXgHwBI	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:P11532	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-295827|uniprotkb:Q9UCW3|uniprotkb:Q9UCW4|uniprotkb:Q02295|uniprotkb:Q14169|uniprotkb:Q14170|uniprotkb:Q5JYU0|uniprotkb:Q7KZ48|intact:EBI-11041646|uniprotkb:A1L0U9|uniprotkb:Q8N754|uniprotkb:E9PDN1|uniprotkb:Q6NSJ9|intact:EBI-12189729|intact:EBI-22423597|intact:EBI-12702600|uniprotkb:E7EQR9|uniprotkb:E7EQS5|uniprotkb:E7ESB2|uniprotkb:E9PDN5|uniprotkb:F5GZY3|uniprotkb:F8VX32|intact:EBI-28985510	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:dmd_human(display_long)|uniprotkb:DMD(gene name)|psi-mi:DMD(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274427|imex:IM-26901-49	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_000100.2|refseq:NP_003997.1|refseq:NP_004000.1|refseq:NP_004001.1|refseq:NP_004002.2|refseq:NP_004003.1|refseq:NP_004004.1|refseq:NP_004005.1|refseq:NP_004008.1|refseq:NP_004009.1|refseq:NP_004010.1|refseq:NP_004011.2|refseq:NP_004012.1|refseq:NP_004013.1|refseq:NP_004014.1|refseq:NP_004006.1|refseq:NP_004007.1|ensembl:ENST00000682600|ensembl:ENSP00000507640|ensembl:ENST00000361471|ensembl:ENSP00000354464|ensembl:ENSG00000198947|ensembl:ENST00000378680|ensembl:ENSP00000367951|ensembl:ENST00000378702|ensembl:ENSP00000367974|ensembl:ENST00000378723|ensembl:ENSP00000367997|mint:P11532|dip:DIP-32593N|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009986"(cell surface)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|rcsb pdb:1DXX|rcsb pdb:1EG3|rcsb pdb:1EG4|rcsb pdb:3UUN|reactome:R-HSA-3000171|reactome:R-HSA-390522	-	-	-	figure legend:Table 2-5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a375)|taxid:9606(Human malignant melanoma)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:gUFSTsQjsZpAmGI3+6ZPmUebofA9606	rigid:nRynYDe2+ccEzGbL8U+2dXgHwBI	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q13425	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-80411|ensembl:ENSP00000338191|uniprotkb:Q9BY09	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:sntb2_human(display_long)|uniprotkb:SNT2B2(gene name synonym)|uniprotkb:SNTB2(gene name)|psi-mi:SNTB2(display_short)|uniprotkb:D16S2531E(gene name synonym)|uniprotkb:SNTL(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 2(gene name synonym)|uniprotkb:Syntrophin-3(gene name synonym)|uniprotkb:Syntrophin-like(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274427|imex:IM-26901-49	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0016020"(membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028550|interpro:IPR036034|interpro:IPR041428|mint:Q13425|rcsb pdb:2VRF|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000168807(gene)|ensembl:ENST00000336278(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_006741.1	-	-	-	figure legend:Table 2-5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a375)|taxid:9606(Human malignant melanoma)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:SABgmvArdLH93OpFobs/L3BleVY9606	rigid:nRynYDe2+ccEzGbL8U+2dXgHwBI	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q14160	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274427|imex:IM-26901-49	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:Table 2-5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a375)|taxid:9606(Human malignant melanoma)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rigid:nRynYDe2+ccEzGbL8U+2dXgHwBI	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:O60941	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-740402|intact:EBI-784159|uniprotkb:O43782|uniprotkb:O60881|ensembl:ENSP00000384084|uniprotkb:O75538|uniprotkb:Q96AW0|uniprotkb:Q9UE14|uniprotkb:Q9UE15|uniprotkb:Q9UE16|uniprotkb:G5E9F6|uniprotkb:Q86VR4|uniprotkb:B7Z733|uniprotkb:F5GZG4	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:dtnb_human(display_long)|uniprotkb:DTNB(gene name)|psi-mi:DTNB(display_short)|uniprotkb:Beta-dystrobrevin(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274427|imex:IM-26901-49	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_001243232.1|refseq:NP_068707.1|refseq:NP_149159.2|refseq:NP_149160.1|refseq:NP_899204.1|ensembl:ENSG00000138101(gene)|ensembl:ENST00000406818(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0045202"(synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:O60941|refseq:NP_001243237.1|refseq:NP_899205.1|refseq:NP_001307861.1|refseq:NP_001307862.1|refseq:NP_001307863.1|refseq:NP_001307864.1|refseq:NP_001307865.1	-	-	-	figure legend:Table 2-5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a375)|taxid:9606(Human malignant melanoma)	-	2019/03/14	2019/03/18	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:/yB9vgxJOii2Uk4riTNLOhf9gUk9606	rigid:nRynYDe2+ccEzGbL8U+2dXgHwBI	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:P46939	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40|ensembl:ENSP00000356515	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274443|imex:IM-26901-51	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	ensembl:ENSP00000356515|refseq:XP_011534408.1|refseq:NP_009055.2|refseq:XP_005267187.1|dip:DIP-711N|ensembl:ENSG00000152818(gene)|ensembl:ENST00000367545(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017166"(vinculin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665	-	-	-	figure legend:Table 2-6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sw480)|taxid:9606(Human SW480 adenocarcinoma cell line)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:metWqbqGtzonNZ1mgNjlFrenuI89606	rigid:ieUHA0axmK9oVKfZfBdo+GbFu+g	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q9Y4J8	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-949471|ensembl:ENSP00000382064|uniprotkb:O15332|uniprotkb:O15333|uniprotkb:O75697|uniprotkb:Q13197|uniprotkb:Q13198|uniprotkb:Q13199|uniprotkb:Q13498|uniprotkb:Q13499|uniprotkb:Q13500|uniprotkb:A8MUY4|uniprotkb:A8K541|uniprotkb:M0QYX6|uniprotkb:A8MSZ0|uniprotkb:Q9BS59|uniprotkb:B4DIU8|uniprotkb:B4DIR0|uniprotkb:B4DGS6|uniprotkb:M0R397|uniprotkb:Q59GK7	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:dtna_human(display_long)|uniprotkb:Alpha-dystrobrevin(gene name synonym)|uniprotkb:Dystrophin-related protein 3(gene name synonym)|uniprotkb:DTNA(gene name)|psi-mi:DTNA(display_short)|uniprotkb:DRP3(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274443|imex:IM-26901-51	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	ensembl:ENSG00000134769(gene)|ensembl:ENST00000399113(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045202"(synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:Q9Y4J8|rcsb pdb:2E5R|interpro:IPR000433(Zinc finger, ZZ-type)|refseq:NP_001185873.1|refseq:NP_001381.2|refseq:NP_001382.2|refseq:NP_001383.2|refseq:NP_116757.2|refseq:NP_116760.2|refseq:NP_116761.2|refseq:NP_116762.2|refseq:NP_116763.1|refseq:XP_011524155.1|refseq:NP_001121647.1|refseq:NP_001185867.1|refseq:NP_001185868.1|refseq:NP_001185871.1|refseq:NP_001185869.1|refseq:NP_001185874.1|refseq:NP_001185870.1|refseq:XP_016881066.1|refseq:XP_016881073.1|refseq:XP_016881076.1|refseq:XP_016881077.1|refseq:XP_016881078.1|refseq:XP_016881079.1|refseq:XP_016881080.1|refseq:XP_016881089.1|refseq:XP_016881090.1|refseq:XP_016881091.1	-	-	-	figure legend:Table 2-6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sw480)|taxid:9606(Human SW480 adenocarcinoma cell line)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:9HaDKLthoXmwdYDzbEer3CRN3O09606	rigid:ieUHA0axmK9oVKfZfBdo+GbFu+g	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q13425	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-80411|ensembl:ENSP00000338191|uniprotkb:Q9BY09	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:sntb2_human(display_long)|uniprotkb:SNT2B2(gene name synonym)|uniprotkb:SNTB2(gene name)|psi-mi:SNTB2(display_short)|uniprotkb:D16S2531E(gene name synonym)|uniprotkb:SNTL(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 2(gene name synonym)|uniprotkb:Syntrophin-3(gene name synonym)|uniprotkb:Syntrophin-like(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274443|imex:IM-26901-51	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0016020"(membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028550|interpro:IPR036034|interpro:IPR041428|mint:Q13425|rcsb pdb:2VRF|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000168807(gene)|ensembl:ENST00000336278(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_006741.1	-	-	-	figure legend:Table 2-6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sw480)|taxid:9606(Human SW480 adenocarcinoma cell line)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:SABgmvArdLH93OpFobs/L3BleVY9606	rigid:ieUHA0axmK9oVKfZfBdo+GbFu+g	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q13884	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-295843|uniprotkb:O14912|uniprotkb:Q4KMG8|uniprotkb:A8K9E0|ensembl:ENSP00000378965|ensembl:ENSP00000431124	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:sntb1_human(display_long)|uniprotkb:SNTB1(gene name)|psi-mi:SNTB1(display_short)|uniprotkb:SNT2B1(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 1(gene name synonym)|uniprotkb:Tax interaction protein 43(gene name synonym)|uniprotkb:Syntrophin-2(gene name synonym)|uniprotkb:BSYN2(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274443|imex:IM-26901-51	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:XP_011515541.1|refseq:NP_066301.1|dip:DIP-466N|ensembl:ENSG00000172164(gene)|ensembl:ENST00000395601(transcript)|ensembl:ENST00000517992(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR036034|interpro:IPR041428|mint:Q13884	-	-	-	figure legend:Table 2-6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sw480)|taxid:9606(Human SW480 adenocarcinoma cell line)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:ysg02ZmUoj12kFHjpHE68vA1lUs9606	rigid:ieUHA0axmK9oVKfZfBdo+GbFu+g	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q14160	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274443|imex:IM-26901-51	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:Table 2-6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sw480)|taxid:9606(Human SW480 adenocarcinoma cell line)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rigid:ieUHA0axmK9oVKfZfBdo+GbFu+g	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q86W92	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-1045582|uniprotkb:O75336|uniprotkb:Q86X70|uniprotkb:Q9NY03|uniprotkb:Q9ULJ0|ensembl:ENSP00000314724	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:lipb1_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1(gene name synonym)|uniprotkb:PPFIBP1(gene name)|psi-mi:PPFIBP1(display_short)|uniprotkb:KIAA1230(gene name synonym)|uniprotkb:hSGT2(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274443|imex:IM-26901-51	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	ensembl:ENSG00000110841(gene)|ensembl:ENST00000318304(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0045296"(cadherin binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030437|interpro:IPR037617|interpro:IPR037618|interpro:IPR037619|mint:Q86W92|reactome:R-HSA-388844|refseq:NP_001185844.1|refseq:NP_001185845.1|refseq:NP_003613.3|refseq:NP_803193.2|dip:DIP-42195N	-	-	-	figure legend:Table 2-6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sw480)|taxid:9606(Human SW480 adenocarcinoma cell line)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:PIoFJHaX4lvBJ0EYcascPgJP8bI9606	rigid:ieUHA0axmK9oVKfZfBdo+GbFu+g	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q12959	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-357481|ensembl:ENSP00000391732|ensembl:ENSP00000407531|ensembl:ENSP00000499437|uniprotkb:Q12958|uniprotkb:A5YKK7|uniprotkb:B7ZMM0|uniprotkb:B9EIQ5|uniprotkb:D3DXB8|uniprotkb:D3DXB9|uniprotkb:B4DGU1|uniprotkb:B4DGZ8|uniprotkb:E7EWL7|uniprotkb:E9PG21	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:dlg1_human(display_long)|uniprotkb:DLG1(gene name)|psi-mi:DLG1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:hDlg(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274443|imex:IM-26901-51	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	reactome:R-HSA-9617324|reactome:R-HSA-9620244|ensembl:ENST00000419354(transcript)|ensembl:ENST00000448528(transcript)|ensembl:ENST00000670935(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|ensembl:ENSG00000075711(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0043113"(receptor clustering)|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|refseq:NP_001091894.1|refseq:NP_001191315.1|refseq:NP_001191316.1|refseq:NP_001191317.1|refseq:NP_004078.2|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030432"(peristalsis)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033268"(node of Ranvier)|go:"GO:0034629"|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|interpro:IPR019583|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q12959|rcsb pdb:1PDR|rcsb pdb:2M3M|rcsb pdb:2OQS|rcsb pdb:2X7Z|rcsb pdb:3LRA|rcsb pdb:3RL7|rcsb pdb:3RL8|rcsb pdb:3W9Y|rcsb pdb:4AMH|rcsb pdb:4G69|reactome:R-HSA-399719|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|reactome:R-HSA-438066|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|reactome:R-HSA-442982|reactome:R-HSA-447038|reactome:R-HSA-451308|reactome:R-HSA-5673001|reactome:R-HSA-8849932|reactome:R-HSA-9609736|refseq:XP_011510804.1|refseq:XP_011510807.1|refseq:XP_011510808.1|refseq:XP_005269346.1|refseq:NP_001277912.1|refseq:XP_016861289.1|refseq:XP_016861290.1|refseq:XP_016861291.1|refseq:XP_016861292.1|refseq:XP_016861294.1|refseq:XP_016861295.1|refseq:XP_016861296.1|refseq:XP_016861297.1|refseq:XP_016861298.1|refseq:XP_016861305.1|refseq:XP_016861306.1|refseq:XP_016861307.1|refseq:XP_016861308.1|refseq:XP_016861309.1|dip:DIP-33957N|refseq:XP_011510805.1|refseq:XP_016861299.1	-	-	-	figure legend:Table 2-6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sw480)|taxid:9606(Human SW480 adenocarcinoma cell line)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:ax5sUROdL8kF59RhocRWG6tUUkc9606	rigid:ieUHA0axmK9oVKfZfBdo+GbFu+g	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q9UBT7	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-514206|uniprotkb:O76084|uniprotkb:Q53FQ2|uniprotkb:Q5JTQ7|uniprotkb:Q5JTQ8|uniprotkb:Q9Y401|uniprotkb:B5BU47|ensembl:ENSP00000320434	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:ctnl1_human(display_long)|uniprotkb:Catenin alpha-like protein 1(gene name synonym)|uniprotkb:Alpha-catenin-related protein(gene name synonym)|uniprotkb:CTNNAL1(gene name)|psi-mi:CTNNAL1(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274443|imex:IM-26901-51	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_003789.1|refseq:NP_001273903.1|dip:DIP-33236N|ensembl:ENSG00000119326(gene)|ensembl:ENST00000325551(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030045|interpro:IPR036723|mint:Q9UBT7	-	-	-	figure legend:Table 2-6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sw480)|taxid:9606(Human SW480 adenocarcinoma cell line)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:4XpDxeBmUk7NAT/aAAhl0c8Sc1w9606	rigid:ieUHA0axmK9oVKfZfBdo+GbFu+g	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:Q13136	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-745426|uniprotkb:Q8N4I2|uniprotkb:Q14567|uniprotkb:A6NLE3|uniprotkb:Q13135|intact:EBI-28983934|ensembl:ENSP00000253925	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:lipa1_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1(gene name synonym)|uniprotkb:LAR-interacting protein 1(gene name synonym)|uniprotkb:PPFIA1(gene name)|psi-mi:PPFIA1(display_short)|uniprotkb:LIP1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274443|imex:IM-26901-51	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_003617.1|refseq:NP_803172.1|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-388844|ensembl:ENSP00000253925|ensembl:ENST00000389547|ensembl:ENSP00000374198|ensembl:ENSG00000131626(gene)|ensembl:ENST00000253925(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030438|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|mint:Q13136|rcsb pdb:1N7F|reactome:R-HSA-181429|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|reactome:R-HSA-181430|reactome:R-HSA-210500	-	-	-	figure legend:Table 2-6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sw480)|taxid:9606(Human SW480 adenocarcinoma cell line)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:uLKfBaRJRh4tvNCQ8WP7rnfrmrU9606	rigid:ieUHA0axmK9oVKfZfBdo+GbFu+g	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:O14910	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-2513988|ensembl:ENSP00000447488|uniprotkb:Q147W1|uniprotkb:Q6LES3|uniprotkb:A4FTY3|uniprotkb:Q7LDS4	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:lin7a_human(display_long)|uniprotkb:LIN7A(gene name)|psi-mi:LIN7A(display_short)|uniprotkb:MALS1(gene name synonym)|uniprotkb:VELI1(gene name synonym)|uniprotkb:Mammalian lin-seven protein 1(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 1(gene name synonym)|uniprotkb:Tax interaction protein 33(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274443|imex:IM-26901-51	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	ensembl:ENSG00000111052(gene)|ensembl:ENST00000552864(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048839"(inner ear development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|mint:O14910|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736|refseq:NP_004655.1	-	-	-	figure legend:Table 2-6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sw480)|taxid:9606(Human SW480 adenocarcinoma cell line)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:Gjtcmp87UCSpimmQfPflbYgJlQc9606	rigid:ieUHA0axmK9oVKfZfBdo+GbFu+g	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:O14936	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-1215506|uniprotkb:Q5VT18|uniprotkb:Q5VT19|uniprotkb:Q66T42|uniprotkb:A6NES1|uniprotkb:O43215|uniprotkb:Q17RI4|uniprotkb:Q59HA0|uniprotkb:Q5VT16|uniprotkb:Q5VT17|uniprotkb:Q9BYH6|uniprotkb:Q9NYB2|uniprotkb:Q9NYB3|uniprotkb:B7ZKY0|ensembl:ENSP00000367405	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:cskp_human(display_long)|uniprotkb:CASK(gene name)|psi-mi:CASK(display_short)|uniprotkb:LIN2(gene name synonym)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:Protein lin-2 homolog(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274443|imex:IM-26901-51	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_001119526.1|refseq:NP_001119527.1|refseq:NP_003679.2|dip:DIP-38727N|ensembl:ENSG00000147044(gene)|ensembl:ENST00000378163(transcript)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031982"(vesicle)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060170"(ciliary membrane)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070509"(calcium ion import)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|rcsb pdb:3MFT|rcsb pdb:3MFU|rcsb pdb:3TAC|rcsb pdb:6KMH|rcsb pdb:7OAI|rcsb pdb:7OAJ|rcsb pdb:7OAK|rcsb pdb:7OAL|reactome:R-HSA-212676|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-6794361|reactome:R-HSA-9609736|reactome:R-HSA-9662360|reactome:R-HSA-9662361|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014775(L27, C-terminal)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:O14936|rcsb pdb:1KGD|rcsb pdb:1KWA|rcsb pdb:1ZL8|rcsb pdb:3C0G|rcsb pdb:3C0H|rcsb pdb:3C0I|rcsb pdb:3MFR|rcsb pdb:3MFS	-	-	-	figure legend:Table 2-6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sw480)|taxid:9606(Human SW480 adenocarcinoma cell line)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:zTaBgQexJON3EVgJq9FHjf+aSCY9606	rigid:ieUHA0axmK9oVKfZfBdo+GbFu+g	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P25100	uniprotkb:O60941	intact:EBI-489993|uniprotkb:Q9NPY0|ensembl:ENSP00000368766	intact:EBI-740402|intact:EBI-784159|uniprotkb:O43782|uniprotkb:O60881|ensembl:ENSP00000384084|uniprotkb:O75538|uniprotkb:Q96AW0|uniprotkb:Q9UE14|uniprotkb:Q9UE15|uniprotkb:Q9UE16|uniprotkb:G5E9F6|uniprotkb:Q86VR4|uniprotkb:B7Z733|uniprotkb:F5GZG4	psi-mi:ada1d_human(display_long)|uniprotkb:Alpha-1D adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1A adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1a(gene name synonym)|uniprotkb:ADRA1D(gene name)|psi-mi:ADRA1D(display_short)|uniprotkb:ADRA1A(gene name synonym)	psi-mi:dtnb_human(display_long)|uniprotkb:DTNB(gene name)|psi-mi:DTNB(display_short)|uniprotkb:Beta-dystrobrevin(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Camp et al. (2014)	pubmed:26617989|imex:IM-26901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21274443|imex:IM-26901-51	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000669.1|ensembl:ENSG00000171873(gene)|ensembl:ENST00000379453(transcript)|go:"GO:0001996"(positive regulation of heart rate by epinephrine-norepinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004937"(alpha1-adrenergic receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000363(Adrenergic receptor, alpha-1A)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-390696|reactome:R-HSA-416476|reactome:R-HSA-416482	refseq:NP_001243232.1|refseq:NP_068707.1|refseq:NP_149159.2|refseq:NP_149160.1|refseq:NP_899204.1|ensembl:ENSG00000138101(gene)|ensembl:ENST00000406818(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0045202"(synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:O60941|refseq:NP_001243237.1|refseq:NP_899205.1|refseq:NP_001307861.1|refseq:NP_001307862.1|refseq:NP_001307863.1|refseq:NP_001307864.1|refseq:NP_001307865.1	-	-	-	figure legend:Table 2-6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sw480)|taxid:9606(Human SW480 adenocarcinoma cell line)	-	2019/03/14	2019/05/30	rogid:jMKKmdeENCQ6B0ulSVJJECThmfE9606	rogid:/yB9vgxJOii2Uk4riTNLOhf9gUk9606	rigid:ieUHA0axmK9oVKfZfBdo+GbFu+g	false	ha tag:n-n|strep tag:n-n|calmodulin binding protein tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)