#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9Y697	uniprotkb:Q9HD34	intact:EBI-1751791|uniprotkb:E1P5R8|uniprotkb:Q6P0L8|uniprotkb:Q9NTZ5|uniprotkb:Q9Y481|uniprotkb:B3KMA5|uniprotkb:B4DXK9|uniprotkb:F5GYK5|ensembl:ENSP00000363205	intact:EBI-3920810|ensembl:ENSP00000418787|uniprotkb:A8K543|uniprotkb:Q5XKP1	psi-mi:nfs1_human(display_long)|uniprotkb:NFS1(gene name)|psi-mi:NFS1(display_short)|uniprotkb:NIFS(gene name synonym)|uniprotkb:HUSSY-08(orf name)	psi-mi:lyrm4_human(display_long)|uniprotkb:LYRM4(gene name)|psi-mi:LYRM4(display_short)|uniprotkb:C6orf149(gene name synonym)|uniprotkb:ISD11(gene name synonym)|uniprotkb:CGI-203(orf name)	psi-mi:"MI:0096"(pull down)	Saha et al. (2015)	pubmed:26342079|imex:IM-27043	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21405779|imex:IM-27043-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001185918.1|refseq:NP_066923.3|ensembl:ENSG00000244005(gene)|ensembl:ENST00000374092(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006777"(Mo-molybdopterin cofactor biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031071"(cysteine desulfurase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR010240(Cysteine desulphurase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR016454(Cysteine desulphurase, NifS)|interpro:IPR020578|rcsb pdb:5KZ5|rcsb pdb:5USR|rcsb pdb:5WGB|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|reactome:R-HSA-947581	refseq:NP_001158313.1|ensembl:ENSG00000214113(gene)|ensembl:ENST00000330636(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016604"(nuclear body)|go:"GO:1990221"(L-cysteine desulfurase complex)|interpro:IPR008011(Complex 1 LYR protein)|rcsb pdb:5USR|rcsb pdb:5WGB|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6ODD|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|refseq:NP_065141.3	-	-	-	figure legend:Figure 3a-3p|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/22	2019/05/22	rogid:tSeWDc9Ch78CnCC2Co+vzC2CWvg9606	rogid:42Smt00XZS1ZIumThh+hX/ARM7M9606	rigid:RGW8S4lckFP7ufeCS5twAO3T7c4	false	his tag:c-c	glutathione s tranferase tag:n-n|mutation decreasing interaction strength:72-72|mutation decreasing interaction strength:40-40|mutation decreasing interaction strength:84-84|mutation decreasing interaction strength:68-68|mutation decreasing interaction strength:69-69|mutation decreasing interaction strength:76-76|mutation decreasing interaction strength:81-81|mutation decreasing interaction strength:63-63|his tag:c-c	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9Y697	uniprotkb:Q9HD34	intact:EBI-1751791|uniprotkb:E1P5R8|uniprotkb:Q6P0L8|uniprotkb:Q9NTZ5|uniprotkb:Q9Y481|uniprotkb:B3KMA5|uniprotkb:B4DXK9|uniprotkb:F5GYK5|ensembl:ENSP00000363205	intact:EBI-3920810|ensembl:ENSP00000418787|uniprotkb:A8K543|uniprotkb:Q5XKP1	psi-mi:nfs1_human(display_long)|uniprotkb:NFS1(gene name)|psi-mi:NFS1(display_short)|uniprotkb:NIFS(gene name synonym)|uniprotkb:HUSSY-08(orf name)	psi-mi:lyrm4_human(display_long)|uniprotkb:LYRM4(gene name)|psi-mi:LYRM4(display_short)|uniprotkb:C6orf149(gene name synonym)|uniprotkb:ISD11(gene name synonym)|uniprotkb:CGI-203(orf name)	psi-mi:"MI:0096"(pull down)	Saha et al. (2015)	pubmed:26342079|imex:IM-27043	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21405863|imex:IM-27043-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001185918.1|refseq:NP_066923.3|ensembl:ENSG00000244005(gene)|ensembl:ENST00000374092(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006777"(Mo-molybdopterin cofactor biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031071"(cysteine desulfurase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR010240(Cysteine desulphurase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR016454(Cysteine desulphurase, NifS)|interpro:IPR020578|rcsb pdb:5KZ5|rcsb pdb:5USR|rcsb pdb:5WGB|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|reactome:R-HSA-947581	refseq:NP_001158313.1|ensembl:ENSG00000214113(gene)|ensembl:ENST00000330636(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016604"(nuclear body)|go:"GO:1990221"(L-cysteine desulfurase complex)|interpro:IPR008011(Complex 1 LYR protein)|rcsb pdb:5USR|rcsb pdb:5WGB|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6ODD|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|refseq:NP_065141.3	go:"GO:0005739"(mitochondrion)	-	-	figure legend:Figure 3q, 3r|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/22	2019/05/28	rogid:tSeWDc9Ch78CnCC2Co+vzC2CWvg9606	rogid:42Smt00XZS1ZIumThh+hX/ARM7M9606	rigid:RGW8S4lckFP7ufeCS5twAO3T7c4	false	glutathione s tranferase tag:n-n	mutation decreasing interaction strength:69-69|mutation decreasing interaction strength:68-68|mutation decreasing interaction strength:63-63|mutation decreasing interaction strength:76-76|mutation decreasing interaction strength:81-81|flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9Y697	uniprotkb:Q9HD34	intact:EBI-1751791|uniprotkb:E1P5R8|uniprotkb:Q6P0L8|uniprotkb:Q9NTZ5|uniprotkb:Q9Y481|uniprotkb:B3KMA5|uniprotkb:B4DXK9|uniprotkb:F5GYK5|ensembl:ENSP00000363205	intact:EBI-3920810|ensembl:ENSP00000418787|uniprotkb:A8K543|uniprotkb:Q5XKP1	psi-mi:nfs1_human(display_long)|uniprotkb:NFS1(gene name)|psi-mi:NFS1(display_short)|uniprotkb:NIFS(gene name synonym)|uniprotkb:HUSSY-08(orf name)	psi-mi:lyrm4_human(display_long)|uniprotkb:LYRM4(gene name)|psi-mi:LYRM4(display_short)|uniprotkb:C6orf149(gene name synonym)|uniprotkb:ISD11(gene name synonym)|uniprotkb:CGI-203(orf name)	psi-mi:"MI:0096"(pull down)	Saha et al. (2015)	pubmed:26342079|imex:IM-27043	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21424758|imex:IM-27043-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001185918.1|refseq:NP_066923.3|ensembl:ENSG00000244005(gene)|ensembl:ENST00000374092(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006777"(Mo-molybdopterin cofactor biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031071"(cysteine desulfurase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR010240(Cysteine desulphurase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR016454(Cysteine desulphurase, NifS)|interpro:IPR020578|rcsb pdb:5KZ5|rcsb pdb:5USR|rcsb pdb:5WGB|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|reactome:R-HSA-947581	refseq:NP_001158313.1|ensembl:ENSG00000214113(gene)|ensembl:ENST00000330636(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016604"(nuclear body)|go:"GO:1990221"(L-cysteine desulfurase complex)|interpro:IPR008011(Complex 1 LYR protein)|rcsb pdb:5USR|rcsb pdb:5WGB|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6ODD|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|refseq:NP_065141.3	go:"GO:0005739"(mitochondrion)	-	-	figure legend:Figure 3s|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/22	2019/05/28	rogid:tSeWDc9Ch78CnCC2Co+vzC2CWvg9606	rogid:42Smt00XZS1ZIumThh+hX/ARM7M9606	rigid:RGW8S4lckFP7ufeCS5twAO3T7c4	false	glutathione s tranferase tag:n-n	mutation decreasing interaction strength:68-68|flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9Y697	uniprotkb:Q9HD34	intact:EBI-1751791|uniprotkb:E1P5R8|uniprotkb:Q6P0L8|uniprotkb:Q9NTZ5|uniprotkb:Q9Y481|uniprotkb:B3KMA5|uniprotkb:B4DXK9|uniprotkb:F5GYK5|ensembl:ENSP00000363205	intact:EBI-3920810|ensembl:ENSP00000418787|uniprotkb:A8K543|uniprotkb:Q5XKP1	psi-mi:nfs1_human(display_long)|uniprotkb:NFS1(gene name)|psi-mi:NFS1(display_short)|uniprotkb:NIFS(gene name synonym)|uniprotkb:HUSSY-08(orf name)	psi-mi:lyrm4_human(display_long)|uniprotkb:LYRM4(gene name)|psi-mi:LYRM4(display_short)|uniprotkb:C6orf149(gene name synonym)|uniprotkb:ISD11(gene name synonym)|uniprotkb:CGI-203(orf name)	psi-mi:"MI:0067"(light scattering)	Saha et al. (2015)	pubmed:26342079|imex:IM-27043	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21415446|imex:IM-27043-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001185918.1|refseq:NP_066923.3|ensembl:ENSG00000244005(gene)|ensembl:ENST00000374092(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006777"(Mo-molybdopterin cofactor biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031071"(cysteine desulfurase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR010240(Cysteine desulphurase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR016454(Cysteine desulphurase, NifS)|interpro:IPR020578|rcsb pdb:5KZ5|rcsb pdb:5USR|rcsb pdb:5WGB|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|reactome:R-HSA-947581	refseq:NP_001158313.1|ensembl:ENSG00000214113(gene)|ensembl:ENST00000330636(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016604"(nuclear body)|go:"GO:1990221"(L-cysteine desulfurase complex)|interpro:IPR008011(Complex 1 LYR protein)|rcsb pdb:5USR|rcsb pdb:5WGB|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6ODD|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|refseq:NP_065141.3	-	-	-	figure legend:Figure 4a-4h|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/22	2019/05/28	rogid:tSeWDc9Ch78CnCC2Co+vzC2CWvg9606	rogid:42Smt00XZS1ZIumThh+hX/ARM7M9606	rigid:RGW8S4lckFP7ufeCS5twAO3T7c4	false	-	mutation disrupting interaction strength:81-81|glutathione s tranferase tag:n-n|mutation disrupting interaction strength:40-40|mutation decreasing interaction strength:63-63|mutation disrupting interaction strength:68-68|mutation disrupting interaction strength:69-69|mutation disrupting interaction strength:72-72|mutation disrupting interaction strength:76-76|mutation disrupting interaction strength:84-84	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)