#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O84008 uniprotkb:P48651 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-8652106|uniprotkb:B4DE85|uniprotkb:E5RFC5|uniprotkb:Q9BUQ5|intact:MINT-8163942|ensembl:ENSP00000430548 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:ptss1_human(display_long)|uniprotkb:PTDSS1(gene name)|psi-mi:PTDSS1(display_short)|uniprotkb:KIAA0024(gene name synonym)|uniprotkb:PSSA(gene name synonym)|uniprotkb:Serine-exchange enzyme I(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_001277154.1|refseq:NP_055569.1|ensembl:ENSG00000156471(gene)|ensembl:ENST00000517309(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016740"(transferase activity)|go:"GO:0106245"(L-serine-phosphatidylethanolamine phosphatidyltransferase activity)|go:"GO:0106258"(L-serine-phosphatidylcholine phosphatidyltransferase activity)|interpro:IPR004277(Phosphatidyl serine synthase)|mint:P48651|reactome:R-HSA-1483101 - - comment:mint figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:FDSRlCB+/84r8jXnvywHmzAqq9s9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q96B49 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-10826510|uniprotkb:B2DG15|uniprotkb:Q9UH52|ensembl:ENSP00000381856|ensembl:ENSP00000381859 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:tom6_human(display_long)|uniprotkb:TOMM6(gene name)|psi-mi:TOMM6(display_short)|uniprotkb:Overexpressed breast tumor protein(gene name synonym)|uniprotkb:Translocase of outer membrane 6 kDa subunit homolog(gene name synonym)|uniprotkb:OBTP(gene name synonym)|uniprotkb:TOM6(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_001127965.1|ensembl:ENSG00000214736(gene)|ensembl:ENST00000398881(transcript)|ensembl:ENST00000398884(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0015031"(protein transport)|interpro:IPR029182|mint:Q96B49|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:j3q/LBZ1XHboUAcHka+T8XtNsIM9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:O14880 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-724754|uniprotkb:Q6ICN4|uniprotkb:B2R592|ensembl:ENSP00000356859|ensembl:ENSP00000356864 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:mgst3_human(display_long)|uniprotkb:MGST3(gene name)|psi-mi:MGST3(display_short)|uniprotkb:Glutathione peroxidase MGST3(gene name synonym)|uniprotkb:LTC4 synthase MGST3(gene name synonym)|uniprotkb:Microsomal glutathione S-transferase III(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_004519.1|refseq:XP_005245231.2|ensembl:ENST00000367889(transcript)|go:"GO:0004464"(leukotriene-C4 synthase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016740"(transferase activity)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001129("Membrane-associated, eicosanoid and glutathione metabolism (MAPEG)")|interpro:IPR023352|mint:O14880|reactome:R-HSA-156590|reactome:R-HSA-5423646|ensembl:ENSG00000143198(gene)|ensembl:ENST00000367884(transcript) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:J7fGwczUzRe0yRbrDkBPsHLZkjY9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:O15258 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-716910|uniprotkb:O95322|ensembl:ENSP00000464222|ensembl:ENSP00000475168 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:rer1_human(display_long)|uniprotkb:RER1(gene name)|psi-mi:RER1(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_008964.3|refseq:XP_011538844.1|refseq:XP_011538845.1|refseq:XP_006710369.1|ensembl:ENSG00000157916(gene)|ensembl:ENST00000488353(transcript)|ensembl:ENST00000605895(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009986"(cell surface)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR004932(Retrieval of early ER protein Rer1)|mint:O15258|refseq:XP_016855622.1|refseq:XP_016855623.1|refseq:XP_016855624.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:rLTZIWGawmaVck0uemR5/E9bFRk9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:O95292 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_001182606.1|refseq:NP_004729.1|ensembl:ENSG00000124164(gene)|ensembl:ENST00000475243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044790"(suppression of viral release by host)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|dip:DIP-39816N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q9Y4P3 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-2513719|ensembl:ENSP00000307260|uniprotkb:Q9UQE2 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:tbl2_human(display_long)|uniprotkb:TBL2(gene name)|psi-mi:TBL2(display_short)|uniprotkb:WBSCR13(gene name synonym)|uniprotkb:WS beta-transducin repeats protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 13 protein(gene name synonym)|uniprotkb:UNQ563/PRO1125(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 ensembl:ENSG00000106638(gene)|ensembl:ENST00000305632(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR042410|mint:Q9Y4P3|refseq:NP_036585.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:K0mFwM08LEIAWO/zg4Irplaq9oM9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q96A33 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-720151|uniprotkb:Q96D00|uniprotkb:Q96JZ7|uniprotkb:Q9H3E4|uniprotkb:Q9NRG3|uniprotkb:B2RAS8|uniprotkb:D3DU20|ensembl:ENSP00000225726|ensembl:ENSP00000384888 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:ccd47_human(display_long)|uniprotkb:CCDC47(gene name)|psi-mi:CCDC47(display_short)|uniprotkb:Calumin(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 47(gene name synonym)|uniprotkb:GK001(orf name)|uniprotkb:MSTP041(orf name)|uniprotkb:PSEC0077(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_064583.2|ensembl:ENSG00000108588(gene)|ensembl:ENST00000225726(transcript)|ensembl:ENST00000403162(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006983"(ER overload response)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043022"(ribosome binding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045048"(protein insertion into ER membrane)|interpro:IPR012879(Protein of unknown function DUF1682)|mint:Q96A33|rcsb pdb:6W6L|go:"GO:0030867"(rough endoplasmic reticulum membrane)|refseq:XP_005257584.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:DdZFzZrrc4culfYoex0Czf/X6SQ9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q96TA2 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-2818916|uniprotkb:Q9UMR9|uniprotkb:Q9H1Q0|uniprotkb:Q5T8D9|uniprotkb:D3DRV8|uniprotkb:D3DRV9|uniprotkb:B4DNM1|intact:EBI-10989776|ensembl:ENSP00000318480 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:ymel1_human(display_long)|uniprotkb:YME1L1(gene name)|psi-mi:YME1L1(display_short)|uniprotkb:FTSH1(gene name synonym)|uniprotkb:YME1L(gene name synonym)|uniprotkb:ATP-dependent metalloprotease FtsH1(gene name synonym)|uniprotkb:Meg-4(gene name synonym)|uniprotkb:Presenilin-associated metalloprotease(gene name synonym)|uniprotkb:YME1-like protein 1(gene name synonym)|uniprotkb:UNQ1868/PRO4304(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_647473.1|refseq:NP_055078.1|refseq:NP_001240795.1|ensembl:ENSG00000136758(gene)|ensembl:ENST00000326799(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q96TA2|reactome:R-HSA-8949664 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:73ThpwDPUEO7f5SBfSljmbwJLn09606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q9NV70 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-1045313|uniprotkb:Q504V4|uniprotkb:Q8WUE7|uniprotkb:Q96T15|uniprotkb:Q9NZE4|ensembl:ENSP00000326514|ensembl:ENSP00000370695 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:exoc1_human(display_long)|uniprotkb:Exocyst complex component Sec3(gene name synonym)|uniprotkb:EXOC1(gene name)|psi-mi:EXOC1(display_short)|uniprotkb:SEC3(gene name synonym)|uniprotkb:SEC3L1(gene name synonym)|uniprotkb:BM-012(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_001020095.1|refseq:NP_060731.2|refseq:NP_839955.1|ensembl:ENSG00000090989(gene)|ensembl:ENST00000346134(transcript)|ensembl:ENST00000381295(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051607"(defense response to virus)|go:"GO:0090543"(Flemming body)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|interpro:IPR019160|interpro:IPR028258|mint:Q9NV70|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:XP_016863898.1|dip:DIP-37579N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:DKEfnn4CJkBSIdGRfVy+znSPOrc9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q7Z2K6 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-10976398|ensembl:ENSP00000340427|ensembl:ENSP00000417160|uniprotkb:B3KSB1|uniprotkb:B2RNA4|uniprotkb:Q9H5M1|uniprotkb:Q8N5T5 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:ermp1_human(display_long)|uniprotkb:ERMP1(gene name)|psi-mi:ERMP1(display_short)|uniprotkb:FXNA(gene name synonym)|uniprotkb:Felix-ina(gene name synonym)|uniprotkb:KIAA1815(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_079172.2|ensembl:ENSG00000099219(gene)|ensembl:ENST00000339450(transcript)|ensembl:ENST00000462592(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|interpro:IPR007484(Peptidase M28)|mint:Q7Z2K6 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:KTUjM61VKt7x03WaW4M8L0OkaJ49606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:O94988 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-10962518|ensembl:ENSP00000264344|uniprotkb:Q8NBA3|uniprotkb:Q24JP0|uniprotkb:Q5PR21|uniprotkb:B4DLC1 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:fa13a_human(display_long)|uniprotkb:FAM13A(gene name)|psi-mi:FAM13A(display_short)|uniprotkb:FAM13A1(gene name synonym)|uniprotkb:KIAA0914(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_001015045.1|refseq:NP_001252507.1|refseq:NP_001252508.1|refseq:NP_001252509.1|refseq:NP_055698.2|refseq:XP_011529818.1|ensembl:ENSG00000138640(gene)|ensembl:ENST00000264344(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039102|mint:O94988|reactome:R-HSA-8980692|reactome:R-HSA-9013149 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:Uwm2VF+xwj4Rc5+KKfgBh7l/M6I9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:O94913 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-2559809|ensembl:ENSP00000298281|uniprotkb:Q6P0X8|uniprotkb:A6H8W7|uniprotkb:O43671 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:pcf11_human(display_long)|uniprotkb:PCF11(gene name)|psi-mi:PCF11(display_short)|uniprotkb:KIAA0824(gene name synonym)|uniprotkb:Pre-mRNA cleavage complex II protein Pcf11(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 ensembl:ENSG00000165494(gene)|ensembl:ENST00000298281(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|mint:O94913|rcsb pdb:6WJH|reactome:R-HSA-6807505|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|refseq:NP_056969.2|dip:DIP-56825N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:UcfmBNhPWm0PbZmQ2LkwK3WvKcU9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q15006 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q9NNW5 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-1568315|uniprotkb:B4DHK2|uniprotkb:Q3MIT1|uniprotkb:Q9UF63|ensembl:ENSP00000477389 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:wdr6_human(display_long)|uniprotkb:WDR6(gene name)|psi-mi:WDR6(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_060501.3|refseq:NP_001307475.1|refseq:NP_001307476.1|ensembl:ENSG00000178252(gene)|ensembl:ENST00000608424(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0030488"(tRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9NNW5|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:gYSDkyuDdKhj387/1P3bhpKJXy89606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:P67870 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-348169|ensembl:ENSP00000365025|ensembl:ENSP00000365026|ensembl:ENSP00000365042|ensembl:ENSP00000372919|ensembl:ENSP00000372925|ensembl:ENSP00000382980|ensembl:ENSP00000390900|ensembl:ENSP00000391038|ensembl:ENSP00000393756|ensembl:ENSP00000394855|ensembl:ENSP00000395275|ensembl:ENSP00000400188|ensembl:ENSP00000407018|ensembl:ENSP00000407379|ensembl:ENSP00000409510|ensembl:ENSP00000410802|ensembl:ENSP00000411322|ensembl:ENSP00000412520|ensembl:ENSP00000413469|ensembl:ENSP00000415237|ensembl:ENSP00000415303|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 ensembl:ENSG00000204435(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENST00000375882(transcript)|ensembl:ENST00000383427(transcript)|ensembl:ENST00000383433(transcript)|ensembl:ENST00000400110(transcript)|ensembl:ENST00000412802(transcript)|ensembl:ENST00000418230(transcript)|ensembl:ENST00000422567(transcript)|ensembl:ENST00000429633(transcript)|ensembl:ENST00000431476(transcript)|ensembl:ENST00000436169(transcript)|ensembl:ENST00000443673(transcript)|ensembl:ENST00000448596(transcript)|ensembl:ENST00000451917(transcript)|ensembl:ENST00000452985(transcript)|ensembl:ENST00000453234(transcript)|ensembl:ENST00000454382(transcript)|ensembl:ENST00000454511(transcript)|ensembl:ENST00000455161(transcript)|ensembl:ENST00000458330(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000375865(transcript)|ensembl:ENST00000375866(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034622"|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|go:"GO:0008134"(transcription factor binding)|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:6Q38|refseq:NP_001311.3|refseq:NP_001269314.1|dip:DIP-131N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q9Y3B3 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-2561467|ensembl:ENSP00000405926|uniprotkb:Q96K51|uniprotkb:Q8WUU6|intact:EBI-10990361|uniprotkb:Q8NBU8 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:tmed7_human(display_long)|uniprotkb:TMED7(gene name)|psi-mi:TMED7(display_short)|uniprotkb:CGI-109(orf name)|uniprotkb:p24 family protein gamma-3(gene name synonym)|uniprotkb:p27(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 ensembl:ENSG00000134970(gene)|ensembl:ENST00000456936(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR009038(GOLD)|interpro:IPR015718(P24 related)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|mint:Q9Y3B3|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_001157941.1|refseq:NP_861974.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:A0B8TdJSOf63pd4GZ65i4VH/M8g9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q13445 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-4310995|ensembl:ENSP00000214869 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:tmed1_human(display_long)|uniprotkb:TMED1(gene name)|psi-mi:TMED1(display_short)|uniprotkb:IL1RL1L(gene name synonym)|uniprotkb:IL1RL1LG(gene name synonym)|uniprotkb:Interleukin-1 receptor-like 1 ligand(gene name synonym)|uniprotkb:Putative T1/ST2 receptor-binding protein(gene name synonym)|uniprotkb:p24 family protein gamma-1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_006849.1|ensembl:ENSG00000099203(gene)|ensembl:ENST00000214869(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|mint:Q13445 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:PQHIGiwN0HhCGcpm1HGn/WF3t9U9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q5HYI8 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-2824032|uniprotkb:Q8WUD3|ensembl:ENSP00000273375 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:rabl3_human(display_long)|uniprotkb:RABL3(gene name)|psi-mi:RABL3(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 ensembl:ENSG00000144840(gene)|ensembl:ENST00000273375(transcript)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0030183"(B cell differentiation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:1903059"(regulation of protein lipidation)|interpro:IPR027417|mint:Q5HYI8|go:"GO:0050821"(protein stabilization)|refseq:NP_776186.2 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:wa/T6PILk7wiphCKdnT3OidKB0E9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q9P0L0 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q15691 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-1004115|uniprotkb:Q3KQS8|uniprotkb:B2R6I7|uniprotkb:E1P5M8|ensembl:ENSP00000364721 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:mare1_human(display_long)|uniprotkb:APC-binding protein EB1(gene name synonym)|uniprotkb:End-binding protein 1(gene name synonym)|uniprotkb:MAPRE1(gene name)|psi-mi:MAPRE1(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_036457.1|refseq:XP_011526998.1|ensembl:ENSG00000101367(gene)|ensembl:ENST00000375571(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0016477"(cell migration)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0030981"(cortical microtubule cytoskeleton)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027739|interpro:IPR036133|interpro:IPR036872|mint:Q15691|rcsb pdb:1PA7|rcsb pdb:1TXQ|rcsb pdb:1UEG|rcsb pdb:1VKA|rcsb pdb:1WU9|rcsb pdb:1YIB|rcsb pdb:1YIG|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2QJZ|rcsb pdb:2R8U|rcsb pdb:3GJO|rcsb pdb:3MTU|rcsb pdb:3MUD|rcsb pdb:3TQ7|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA6|rcsb pdb:5JV3|rcsb pdb:5JVM|rcsb pdb:5JVP|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:5JX1|rcsb pdb:5WLQ|rcsb pdb:6PF2|rcsb pdb:6PFP|rcsb pdb:6YF5|rcsb pdb:6YSH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|dip:DIP-38018N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:+JBCBM7dbbrxn6mX8RiwejYWJ2U9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q96AG4 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|ensembl:ENSP00000225972|uniprotkb:B2RE83 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_060979.2|ensembl:ENSG00000108829(gene)|ensembl:ENST00000225972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045296"(cadherin binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q96AG4 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:O95159 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-718439|uniprotkb:O14616|uniprotkb:Q9UID0|uniprotkb:A8K7E9|ensembl:ENSP00000294258 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:zfpl1_human(display_long)|uniprotkb:Zinc finger protein MCG4(gene name synonym)|uniprotkb:ZFPL1(gene name)|psi-mi:ZFPL1(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_006773.2|ensembl:ENSG00000162300(gene)|ensembl:ENST00000294258(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR039043|mint:O95159 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:8U/G+YcD/pF1Cg44ghFOW+D8tD89606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q9H0U3 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-2798816|uniprotkb:Q6P577|uniprotkb:B2RAR4|uniprotkb:Q53G00|uniprotkb:Q8NBN6|uniprotkb:D3DTE3|ensembl:ENSP00000354649|ensembl:ENSP00000480732 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:magt1_human(display_long)|uniprotkb:IAG2(gene name synonym)|uniprotkb:Implantation-associated protein(gene name synonym)|uniprotkb:PSEC0084(orf name)|uniprotkb:UNQ628/PRO1244(orf name)|uniprotkb:MAGT1(gene name)|psi-mi:MAGT1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_115497.4|ensembl:ENSG00000102158(gene)|ensembl:ENST00000358075(transcript)|ensembl:ENST00000618282(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0055085"(transmembrane transport)|interpro:IPR006844(OST3/OST6)|interpro:IPR021149|interpro:IPR036249|mint:Q9H0U3|rcsb pdb:6S7T|reactome:R-HSA-446203|reactome:R-HSA-5223345|reactome:R-HSA-6798695|reactome:R-HSA-9694548|go:"GO:0050890"(cognition) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:M7/LTAlkuCCyeqlTlcJkfu2HU9k9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:P48729 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-1383726|uniprotkb:Q96HD2|uniprotkb:Q5U046|uniprotkb:Q5U047|uniprotkb:Q6FGA2|uniprotkb:Q4JJA0|uniprotkb:Q9UDK3|intact:EBI-11048253|uniprotkb:D3DQG0|uniprotkb:D3DQG1|uniprotkb:Q71TU5|ensembl:ENSP00000367074 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:kc1a_human(display_long)|uniprotkb:CSNK1A1(gene name)|psi-mi:CSNK1A1(display_short)|uniprotkb:CK1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_001020276.1|refseq:NP_001883.4|refseq:NP_001258670.1|refseq:NP_001258671.1|dip:DIP-40367N|ensembl:ENSG00000113712(gene)|ensembl:ENST00000377843(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0051301"(cell division)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904424"(regulation of GTP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P48729|rcsb pdb:5FQD|rcsb pdb:6GZD|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5635838 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:2rG1/sMVnsRKUEWsLhLAyHvqPnY9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:P19784 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-347451|ensembl:ENSP00000262506 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q7LGA3 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-5461291|ensembl:ENSP00000359581|uniprotkb:D3DT22|uniprotkb:O75036|uniprotkb:Q32NB5|uniprotkb:Q8TAC5|uniprotkb:Q9H441|uniprotkb:Q9NUJ9 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:hs2st_human(display_long)|uniprotkb:HS2ST1(gene name)|psi-mi:HS2ST1(display_short)|uniprotkb:HS2ST(gene name synonym)|uniprotkb:KIAA0448(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 ensembl:ENSG00000153936(gene)|ensembl:ENST00000370550(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004394"(heparan sulfate 2-O-sulfotransferase activity)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0008146"(sulfotransferase activity)|go:"GO:0015014"(heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process)|go:"GO:0015015"(heparan sulfate proteoglycan biosynthetic process, enzymatic modification)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007734(Heparan sulphate 2-O-sulphotransferase)|interpro:IPR027417|mint:Q7LGA3|reactome:R-HSA-2022928|interpro:IPR005331(Carbohydrate sulphotransferase, 8-13)|refseq:NP_001127964.1|refseq:NP_036394.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:96+iUitOmSLSpaEzhZu+9fZXLEQ9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:P68400 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:P48426 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-3924422|uniprotkb:Q5VUX3|uniprotkb:D3DRV1|uniprotkb:B0YJ66|uniprotkb:P53807|ensembl:ENSP00000365757|uniprotkb:B4DGX2 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:pi42a_human(display_long)|uniprotkb:PIP4K2A(gene name)|psi-mi:PIP4K2A(display_short)|uniprotkb:PIP5K2(gene name synonym)|uniprotkb:PIP5K2A(gene name synonym)|uniprotkb:Diphosphoinositide kinase 2-alpha(gene name synonym)|uniprotkb:PIP5KIII(gene name synonym)|uniprotkb:"PtdIns(4)P-5-kinase B isoform"(gene name synonym)|uniprotkb:"PtdIns(4)P-5-kinase C isoform"(gene name synonym)|uniprotkb:"PtdIns(5)P-4-kinase isoform 2-alpha"(gene name synonym)|uniprotkb:1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha(gene name synonym)|uniprotkb:Phosphatidylinositol 5-phosphate 4-kinase type II alpha(gene name synonym)|uniprotkb:PI5P4KA(gene name synonym)|uniprotkb:Phosphatidylinositol 5-Phosphate 4-Kinase(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_005019.2|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0016309"(1-phosphatidylinositol-5-phosphate 4-kinase activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:0090119"(vesicle-mediated cholesterol transport)|go:"GO:0090217"(negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity)|ensembl:ENST00000376573(transcript)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:P48426|rcsb pdb:2YBX|rcsb pdb:6OSP|rcsb pdb:6UX9|rcsb pdb:6YM3|rcsb pdb:6YM4|rcsb pdb:6YM5|rcsb pdb:7N6Z|rcsb pdb:7N7J|rcsb pdb:7N7K|rcsb pdb:7N7L|rcsb pdb:7N7M|rcsb pdb:7N7N|rcsb pdb:7N7O|reactome:R-HSA-1660499|reactome:R-HSA-6811555|reactome:R-HSA-6811558|reactome:R-HSA-8847453|go:"GO:1902635"(1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process)|ensembl:ENSG00000150867(gene)|refseq:NP_001316991.1|refseq:XP_016871819.1|refseq:XP_016871820.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:Fmsp/H2ucCjs7wyiCgEqe9Y5UT49606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:P32121 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-714559|uniprotkb:Q0Z8D3|uniprotkb:Q2PP19|uniprotkb:Q6ICT3|uniprotkb:Q8N7Y2|uniprotkb:Q9UEQ6|uniprotkb:B7WPL3|uniprotkb:B5B0C0|uniprotkb:D3DTK2|intact:EBI-28974065|ensembl:ENSP00000269260|uniprotkb:B4DLW0|uniprotkb:H0Y688 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:arrb2_human(display_long)|uniprotkb:Arrestin beta-2(gene name synonym)|uniprotkb:ARRB2(gene name)|psi-mi:ARRB2(display_short)|uniprotkb:ARB2(gene name synonym)|uniprotkb:ARR2(gene name synonym)|uniprotkb:Non-visual arrestin-3(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 ensembl:ENSP00000269260|ensembl:ENST00000346341|ensembl:ENSP00000341895|ensembl:ENST00000381488|ensembl:ENSP00000370898|ensembl:ENST00000412477|ensembl:ENSP00000403701|ensembl:ENSG00000141480(gene)|ensembl:ENST00000269260(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002032"(desensitization of G protein-coupled receptor signaling pathway by arrestin)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR017864|go:"GO:0005634"(nucleus)|mint:P32121|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-456926|reactome:R-HSA-5099900|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|interpro:IPR014756(Immunoglobulin E-set)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031859"(platelet activating factor receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0005829"(cytosol)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0005886"(plasma membrane)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:0007212"(dopamine receptor signaling pathway)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|go:"GO:0007420"(brain development)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|go:"GO:0007628"(adult walking behavior)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|refseq:NP_004304.1|refseq:NP_945355.1|refseq:NP_001316993.1|refseq:NP_001244259.1|refseq:NP_001244260.1|refseq:NP_001244257.1|refseq:NP_001244258.1|dip:DIP-40089N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:MY34flMH9cdhPtMLGYOQtoQyr2U9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:P78356 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-947090|uniprotkb:Q5U0E8|uniprotkb:Q8TBP2|ensembl:ENSP00000480776|ensembl:ENSP00000482548 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:pi42b_human(display_long)|uniprotkb:PIP4K2B(gene name)|psi-mi:PIP4K2B(display_short)|uniprotkb:"PtdIns(5)P-4-kinase isoform 2-beta"(gene name synonym)|uniprotkb:Diphosphoinositide kinase 2-beta(gene name synonym)|uniprotkb:PIP5K2B(gene name synonym)|uniprotkb:1-phosphatidylinositol 5-phosphate 4-kinase 2-beta(gene name synonym)|uniprotkb:Phosphatidylinositol 5-phosphate 4-kinase type II beta(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_003550.1|ensembl:ENSG00000276293(gene)|ensembl:ENSG00000277292(gene)|ensembl:ENST00000613180(transcript)|ensembl:ENST00000619039(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0016309"(1-phosphatidylinositol-5-phosphate 4-kinase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:0090217"(negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:1902635"(1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:P78356|rcsb pdb:1BO1|rcsb pdb:3WZZ|rcsb pdb:3X01|rcsb pdb:3X02|rcsb pdb:3X03|rcsb pdb:3X04|rcsb pdb:3X05|rcsb pdb:3X06|rcsb pdb:3X07|rcsb pdb:3X08|rcsb pdb:3X09|rcsb pdb:3X0A|rcsb pdb:3X0B|rcsb pdb:3X0C|rcsb pdb:6K4G|rcsb pdb:6K4H|rcsb pdb:7N80|rcsb pdb:7N81|reactome:R-HSA-1660499|reactome:R-HSA-6811555|reactome:R-HSA-6811558|reactome:R-HSA-8847453 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:sKU3t4ChBZODcGl1ZUqfncyNkSo9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:P49674 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-749343|ensembl:ENSP00000352929|ensembl:ENSP00000380044|ensembl:ENSP00000384074 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:kc1e_human(display_long)|uniprotkb:CSNK1E(gene name)|psi-mi:CSNK1E(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_001885.1|refseq:NP_689407.1|refseq:NP_001276841.1|dip:DIP-38050N|ensembl:ENSG00000213923(gene)|ensembl:ENST00000359867(transcript)|ensembl:ENST00000396832(transcript)|ensembl:ENST00000403904(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903827"|go:"GO:0005829"(cytosol)|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-400253|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49674|rcsb pdb:4HNI|rcsb pdb:4HOK|reactome:R-HSA-201688|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:evdzz03ba4MFWavN9xRae/Wxwio9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q8TBX8 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-1383637|ensembl:ENSP00000347032|ensembl:ENSP00000439878|uniprotkb:Q9H6N2|uniprotkb:B2RDL3|uniprotkb:B4DM11|uniprotkb:B4DY44 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:pi42c_human(display_long)|uniprotkb:PIP4K2C(gene name)|psi-mi:PIP4K2C(display_short)|uniprotkb:PIP5K2C(gene name synonym)|uniprotkb:Phosphatidylinositol 5-phosphate 4-kinase type II gamma(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 ensembl:ENSG00000166908(gene)|ensembl:ENST00000354947(transcript)|ensembl:ENST00000540759(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0016309"(1-phosphatidylinositol-5-phosphate 4-kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043229"(intracellular organelle)|refseq:NP_001139730.1|refseq:NP_001139731.1|refseq:NP_079055.3|refseq:NP_001139732.1|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:Q8TBX8|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090217"(negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:1902635"(1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process)|go:"GO:2000786"(positive regulation of autophagosome assembly)|rcsb pdb:2GK9|reactome:R-HSA-1660499|reactome:R-HSA-6811555|reactome:R-HSA-6811558|reactome:R-HSA-8847453 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:vC4KtXa6EcyihfFZdCAb3GmQUhs9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q9BXS5 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-541426|ensembl:ENSP00000291439|uniprotkb:Q4TTY5 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:ap1m1_human(display_long)|uniprotkb:Golgi adaptor HA1/AP1 adaptin mu-1 subunit(gene name synonym)|uniprotkb:Mu-adaptin 1(gene name synonym)|uniprotkb:AP-mu chain family member mu1A(gene name synonym)|uniprotkb:Mu1A-adaptin(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP47(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP47(gene name synonym)|uniprotkb:Adaptor protein complex AP-1 subunit mu-1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 mu-1 medium chain 1(gene name synonym)|uniprotkb:AP1M1(gene name)|psi-mi:AP1M1(display_short)|uniprotkb:CLTNM(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit mu-1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_115882.1|ensembl:ENSG00000072958(gene)|ensembl:ENST00000291439(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032438"(melanosome organization)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR028565|interpro:IPR036168|mint:Q9BXS5|reactome:R-HSA-164940|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6798695|refseq:NP_001123996.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:B6OVovdusOdmvB0D+RIyhRRga2Q9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q96CW1 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-297683|ensembl:ENSP00000292807|uniprotkb:A6NE12|uniprotkb:P20172|uniprotkb:P53679|uniprotkb:D3DNT1 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:ap2m1_human(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit mu(gene name synonym)|uniprotkb:AP-2 mu chain(gene name synonym)|uniprotkb:AP2M1(gene name)|psi-mi:AP2M1(display_short)|uniprotkb:CLAPM1(gene name synonym)|uniprotkb:KIAA0109(gene name synonym)|uniprotkb:Adaptin-mu2(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 50 kDa protein(gene name synonym)|uniprotkb:HA2 50 kDa subunit(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP50(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP50(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 mu medium chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit mu(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 ensembl:ENSG00000161203(gene)|ensembl:ENST00000292807(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0034622"|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0031623"(receptor internalization)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|interpro:IPR043512|interpro:IPR043532|mint:Q96CW1|rcsb pdb:1H6E|rcsb pdb:6BNT|rcsb pdb:6URI|reactome:R-HSA-164939|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|reactome:R-HSA-182218|refseq:NP_001020376.1|refseq:NP_004059.2|refseq:NP_001298127.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:AyJEJTqzHtIRWEnMGBzLQP3H5lA9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q86Y07 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-1207615|uniprotkb:Q49AK9|uniprotkb:Q53EU9|uniprotkb:Q86Y08|uniprotkb:Q86Y09|uniprotkb:Q86Y10|uniprotkb:Q86Y11|uniprotkb:Q86Y12|uniprotkb:Q8IXI5|uniprotkb:Q99987|uniprotkb:Q53S39|uniprotkb:Q53S77|uniprotkb:Q53TU1|uniprotkb:B4DKL0|uniprotkb:D6W5D4|uniprotkb:D6W5D6|ensembl:ENSP00000342381|ensembl:ENSP00000408002 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:vrk2_human(display_long)|uniprotkb:VRK2(gene name)|psi-mi:VRK2(display_short)|uniprotkb:Vaccinia-related kinase 2(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:XP_011531394.1|refseq:XP_006712153.1|refseq:XP_006712154.1|refseq:XP_006712155.1|refseq:XP_006712156.1|refseq:NP_001123952.1|refseq:NP_001123953.1|refseq:NP_001123954.1|refseq:NP_001123955.1|refseq:NP_006287.2|refseq:NP_001275765.1|refseq:NP_001275766.1|refseq:NP_001275767.1|refseq:NP_001275768.1|refseq:XP_005264597.1|refseq:XP_016860347.1|refseq:XP_016860348.1|refseq:XP_016860349.1|refseq:XP_016860350.1|refseq:XP_016860351.1|refseq:XP_016860352.1|ensembl:ENSG00000028116(gene)|ensembl:ENST00000340157(transcript)|ensembl:ENST00000435505(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000659"(regulation of interleukin-1-mediated signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:Q86Y07|rcsb pdb:2V62|rcsb pdb:5UU1|rcsb pdb:6NCG|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:sDftNP5rKcTUJgpJAcbJsNzag0I9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q7L804 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-1049676|uniprotkb:A6NEI4|uniprotkb:Q9Y2F0|intact:EBI-28973556|ensembl:ENSP00000347839|uniprotkb:Q3I768 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:rfip2_human(display_long)|uniprotkb:NRip11(gene name synonym)|uniprotkb:RAB11FIP2(gene name)|psi-mi:RAB11FIP2(display_short)|uniprotkb:KIAA0941(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 ensembl:ENSP00000347839|ensembl:ENST00000369199|ensembl:ENSP00000358200|refseq:NP_001317096.1|refseq:NP_055719.1|interpro:IPR035892|interpro:IPR037245|interpro:IPR037789|mint:Q7L804|rcsb pdb:2GZD|rcsb pdb:2GZH|rcsb pdb:2K6S|rcsb pdb:3TSO|rcsb pdb:4C4P|rcsb pdb:6S8X|reactome:R-HSA-432040|interpro:IPR019018|ensembl:ENSG00000107560(gene)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0006909"(phagocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|ensembl:ENST00000355624(transcript)|dip:DIP-29139N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:SM9AVuCsVKsV/VsI6FyQuZyq/xE9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q8NHP6 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q9ULK5 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-1054279|uniprotkb:Q5T212|uniprotkb:D3DVE9|ensembl:ENSP00000357040 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:vang2_human(display_long)|uniprotkb:Van Gogh-like protein 2(gene name synonym)|uniprotkb:Strabismus 1(gene name synonym)|uniprotkb:Loop-tail protein 1 homolog(gene name synonym)|uniprotkb:VANGL2(gene name)|psi-mi:VANGL2(display_short)|uniprotkb:KIAA1215(gene name synonym)|uniprotkb:STB1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_065068.1|refseq:XP_011508106.1|refseq:XP_005245414.1|ensembl:ENSG00000162738(gene)|ensembl:ENST00000368061(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0035787"(cell migration involved in kidney development)|go:"GO:0045176"(apical protein localization)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009539(Strabismus)|mint:Q9ULK5|rcsb pdb:6XA6|rcsb pdb:6XA7|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:x6JAZMeK90S/m6+oSp/W1tN1Cjc9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q8TAA9 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-682393|uniprotkb:Q86WG8|uniprotkb:Q8N559|uniprotkb:Q5T1D3|uniprotkb:Q5T1D4|ensembl:ENSP00000310800|ensembl:ENSP00000347672|ensembl:ENSP00000358522 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:vang1_human(display_long)|uniprotkb:Van Gogh-like protein 1(gene name synonym)|uniprotkb:Strabismus 2(gene name synonym)|uniprotkb:Loop-tail protein 2 homolog(gene name synonym)|uniprotkb:VANGL1(gene name)|psi-mi:VANGL1(display_short)|uniprotkb:STB2(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_001165882.1|refseq:NP_001165883.1|refseq:NP_620409.1|ensembl:ENSG00000173218(gene)|ensembl:ENST00000310260(transcript)|ensembl:ENST00000355485(transcript)|ensembl:ENST00000369509(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0043473"(pigmentation)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR009539(Strabismus)|mint:Q8TAA9|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:TRLqwMf+W5eZcgW8gT5S1zM9VzU9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q9BXF6 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-1387068|uniprotkb:O94939|uniprotkb:Q9P0M1|ensembl:ENSP00000258098 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:rfip5_human(display_long)|uniprotkb:RAB11FIP5(gene name)|psi-mi:RAB11FIP5(display_short)|uniprotkb:GAF1(gene name synonym)|uniprotkb:KIAA0857(gene name synonym)|uniprotkb:RIP11(gene name synonym)|uniprotkb:Rab11-interacting protein Rip11(gene name synonym)|uniprotkb:Gamma-SNAP-associated factor 1(gene name synonym)|uniprotkb:Phosphoprotein pp75(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_056285.1|ensembl:ENSG00000135631(gene)|ensembl:ENST00000258098(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0030141"(secretory granule)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070164"(negative regulation of adiponectin secretion)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:2000008"(regulation of protein localization to cell surface)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR019018|interpro:IPR035892|interpro:IPR037245|interpro:IPR037789|mint:Q9BXF6|go:"GO:0034451"(centriolar satellite) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:X3eYUlRpL+nSmU4gfUEA5RntseY9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q9HDC5 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-465137|ensembl:ENSP00000344488|uniprotkb:B2RTZ0 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:jph1_human(display_long)|uniprotkb:JPH1(gene name)|psi-mi:JPH1(display_short)|uniprotkb:JP1(gene name synonym)|uniprotkb:Junctophilin type 1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 ensembl:ENSG00000104369(gene)|ensembl:ENST00000342232(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030314"(junctional membrane complex)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060402"(calcium ion transport into cytosol)|interpro:IPR003409(MORN motif)|interpro:IPR017191(Junctophilin)|mint:Q9HDC5|refseq:NP_065698.1|refseq:NP_001304759.1|refseq:XP_005251331.1|refseq:XP_005251332.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:bx+PVSZHNt7kqkjWVW/vYc8Iqek9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q8TAF3 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_065890.1|ensembl:ENSG00000114742(gene)|ensembl:ENST00000302313(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043588"(skin development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1902525"(regulation of protein monoubiquitination)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|dip:DIP-50841N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q9UER7 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q12797 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-2967294|ensembl:ENSP00000368767|uniprotkb:B4E2K4|uniprotkb:F5H667|uniprotkb:Q9NRI0|uniprotkb:Q9Y4J0|uniprotkb:Q9H2C4|uniprotkb:A6NDF4|uniprotkb:Q9NRI1|uniprotkb:A6NHI2|uniprotkb:B4DIC9|uniprotkb:B7ZM95|uniprotkb:E5RGP5|uniprotkb:Q6NXR7|uniprotkb:Q8TB28|uniprotkb:Q9H291|intact:EBI-8994140|uniprotkb:A0A0A0MSK8 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:asph_human(display_long)|uniprotkb:ASPH(gene name)|psi-mi:ASPH(display_short)|uniprotkb:Aspartate beta-hydroxylase(gene name synonym)|uniprotkb:Peptide-aspartate beta-dioxygenase(gene name synonym)|uniprotkb:BAH(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 ensembl:ENSG00000198363(gene)|ensembl:ENST00000379454(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009055"(electron transfer activity)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031585"(regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033198"(response to ATP)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0062101"(peptidyl-aspartic acid 3-dioxygenase activity)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR007803(Aspartyl/Asparaginyl beta-hydroxylase)|interpro:IPR007943(Aspartyl beta-hydroxylase, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5APA|rcsb pdb:5JQY|interpro:IPR019734|rcsb pdb:5JTC|interpro:IPR027443|interpro:IPR039038|rcsb pdb:5JZ6|mint:Q12797|rcsb pdb:5JZ8|rcsb pdb:5JZA|rcsb pdb:5JZU|rcsb pdb:6Q9F|rcsb pdb:6Q9I|rcsb pdb:6QA5|rcsb pdb:6RK9|rcsb pdb:6YYU|rcsb pdb:6YYV|rcsb pdb:6YYW|rcsb pdb:6YYX|rcsb pdb:6YYY|rcsb pdb:6Z6Q|rcsb pdb:6Z6R|rcsb pdb:7BMI|rcsb pdb:7BMJ|rcsb pdb:7E6J|reactome:R-HSA-5578775|reactome:R-HSA-2672351|refseq:NP_001158222.1|refseq:NP_004309.2|refseq:NP_064549.1|refseq:NP_115855.1|refseq:NP_115856.1|refseq:NP_001158223.1|refseq:NP_001158225.1|refseq:NP_001158227.1|refseq:NP_001158228.1|refseq:NP_115857.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:8Sv1CuwqdVCK6/PF6kL0hkX3/tw9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q8TCJ2 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-2256290|uniprotkb:Q96JZ4|uniprotkb:Q96KY7|ensembl:ENSP00000295770 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:stt3b_human(display_long)|uniprotkb:STT3B(gene name)|psi-mi:STT3B(display_short)|uniprotkb:SIMP(gene name synonym)|uniprotkb:Source of immunodominant MHC-associated peptides homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_849193.1|ensembl:ENSG00000163527(gene)|ensembl:ENST00000295770(transcript)|go:"GO:0004579"(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034998"(oligosaccharyltransferase I complex)|go:"GO:0043686"(co-translational protein modification)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|mint:Q8TCJ2|rcsb pdb:6S7T - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:4F+9LbIZTFRoczuphd1jzuhnFDo9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:O94973 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-1642835|uniprotkb:O75403|uniprotkb:Q96SI8|uniprotkb:Q53ET1|ensembl:ENSP00000413234 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:ap2a2_human(display_long)|uniprotkb:AP2A2(gene name)|psi-mi:AP2A2(display_short)|uniprotkb:ADTAB(gene name synonym)|uniprotkb:CLAPA2(gene name synonym)|uniprotkb:HYPJ(gene name synonym)|uniprotkb:KIAA0899(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Huntingtin-interacting protein J(gene name synonym)|uniprotkb:Huntingtin yeast partner J(gene name synonym)|uniprotkb:HIP9(gene name synonym)|uniprotkb:Huntingtin-interacting protein 9(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_001229766.1|refseq:NP_036437.1|ensembl:ENST00000448903(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:O94973|reactome:R-HSA-167590|ensembl:ENSG00000183020(gene)|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-6798695|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:sda1msOBssgmBiU3ZfSyk3z7/jc9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q10567 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-1171303|uniprotkb:P78436|uniprotkb:C9JRD1|uniprotkb:Q20WL3|intact:EBI-11577132|uniprotkb:F8WDL0|uniprotkb:Q86X54|ensembl:ENSP00000319361|ensembl:ENSP00000350199|ensembl:ENSP00000384194|ensembl:ENSP00000400065 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:ap1b1_human(display_long)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:AP1B1(gene name)|psi-mi:AP1B1(display_short)|uniprotkb:ADTB1(gene name synonym)|uniprotkb:BAM22(gene name synonym)|uniprotkb:CLAPB2(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_001118.3|refseq:NP_663782.2|refseq:NP_001159491.1|ensembl:ENSG00000100280(gene)|ensembl:ENST00000317368(transcript)|ensembl:ENST00000357586(transcript)|ensembl:ENST00000405198(transcript)|ensembl:ENST00000432560(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001822"(kidney development)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:Q10567|rcsb pdb:4HMY|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|reactome:R-HSA-164940|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|rcsb pdb:6CRI|dip:DIP-24207N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:D0i+5PXwzbBmOSyeCOSFKZx8fQk9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:O95782 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-353552|uniprotkb:Q96CI7|uniprotkb:Q96PP6|uniprotkb:Q96PP7|uniprotkb:Q9H070|intact:EBI-28973302|ensembl:ENSP00000351926 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:ap2a1_human(display_long)|uniprotkb:AP2A1(gene name)|psi-mi:AP2A1(display_short)|uniprotkb:ADTAA(gene name synonym)|uniprotkb:CLAPA1(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-1(gene name synonym)|uniprotkb:Alpha1-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit(gene name synonym)|uniprotkb:Alpha-adaptin A(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-A large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein A(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_055018.2|refseq:NP_570603.2|ensembl:ENST00000354293|ensembl:ENSP00000346246|ensembl:ENSP00000351926|ensembl:ENSG00000196961(gene)|ensembl:ENST00000359032(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0032433"(filopodium tip)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:O95782|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|dip:DIP-33164N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:egkaIAhvIi1FqNr+8KEFeJaYZcc9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q05397 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-702142|uniprotkb:Q14291|uniprotkb:Q9UD85|intact:EBI-11047590|uniprotkb:J3QT16|uniprotkb:Q8IYN9|uniprotkb:B4E2N6|uniprotkb:F5H4S4|ensembl:ENSP00000429474|ensembl:ENSP00000429911 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:fak1_human(display_long)|uniprotkb:PTK2(gene name)|psi-mi:PTK2(display_short)|uniprotkb:FAK(gene name synonym)|uniprotkb:FAK1(gene name synonym)|uniprotkb:pp125FAK(gene name synonym)|uniprotkb:Protein-tyrosine kinase 2(gene name synonym)|uniprotkb:Focal adhesion kinase-related nonkinase(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 71(gene name synonym)|uniprotkb:p125FAK(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_722560.1|refseq:NP_001186578.1|ensembl:ENST00000340930|ensembl:ENSP00000341189|ensembl:ENST00000395218|ensembl:ENSP00000378644|ensembl:ENSP00000429474|ensembl:ENSP00000429911|refseq:XP_016869162.1|ensembl:ENSG00000169398(gene)|ensembl:ENST00000521059(transcript)|ensembl:ENST00000522684(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001725"(stress fiber)|go:"GO:0001890"(placenta development)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016477"(cell migration)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048870"(cell motility)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1900024"(regulation of substrate adhesion-dependent cell spreading)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR005189(Focal adhesion targeting region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR029071|interpro:IPR035963|interpro:IPR036137|interpro:IPR041390|interpro:IPR041784|mint:Q05397|rcsb pdb:1K04|rcsb pdb:1K05|rcsb pdb:1MP8|rcsb pdb:1OW6|rcsb pdb:1OW7|rcsb pdb:1OW8|rcsb pdb:2ETM|rcsb pdb:2IJM|rcsb pdb:3B71|rcsb pdb:3BZ3|rcsb pdb:3PXK|rcsb pdb:3S9O|rcsb pdb:4EBV|rcsb pdb:4EBW|rcsb pdb:4GU6|rcsb pdb:4GU9|rcsb pdb:4I4E|rcsb pdb:4I4F|rcsb pdb:4K8A|rcsb pdb:4K9Y|rcsb pdb:4KAB|rcsb pdb:4KAO|rcsb pdb:4NY0|rcsb pdb:4Q9S|rcsb pdb:6I8Z|rcsb pdb:6LES|rcsb pdb:6PW8|rcsb pdb:6YOJ|rcsb pdb:6YQ1|rcsb pdb:6YR9|rcsb pdb:6YT6|rcsb pdb:6YVS|rcsb pdb:6YVY|rcsb pdb:6YXV|reactome:R-HSA-111465|reactome:R-HSA-2029482|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-375165|reactome:R-HSA-391160|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-5673001|reactome:R-HSA-8874081|reactome:R-HSA-9009391|reactome:R-HSA-9634638|reactome:R-HSA-9664422 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:8q4JfaNYtMdXVLU77d1EtSP0lVg9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:P20585 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-1164205|uniprotkb:Q6PJT5|uniprotkb:Q86UQ6|uniprotkb:Q92867|uniprotkb:A6NMM6|uniprotkb:A1L482|uniprotkb:A1L480|ensembl:ENSP00000265081 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:msh3_human(display_long)|uniprotkb:Divergent upstream protein(gene name synonym)|uniprotkb:Mismatch repair protein 1(gene name synonym)|uniprotkb:MSH3(gene name)|psi-mi:MSH3(display_short)|uniprotkb:DUC1(gene name synonym)|uniprotkb:DUG(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_002430.3|go:"GO:0032302"(MutSbeta complex)|go:"GO:0043111"(replication fork arrest)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|mint:P20585|rcsb pdb:3THW|rcsb pdb:3THX|rcsb pdb:3THY|rcsb pdb:3THZ|reactome:R-HSA-5358606|reactome:R-HSA-5632927|reactome:R-HSA-5632928|go:"GO:0032300"(mismatch repair complex)|ensembl:ENSG00000113318(gene)|ensembl:ENST00000265081(transcript)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000735"(removal of nonhomologous ends)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006312"(mitotic recombination)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016020"(membrane)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019899"(enzyme binding)|go:"GO:0032135"(DNA insertion or deletion binding)|dip:DIP-35127N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:6nxGZyJMsk7NfSFhDftKiT/omSE9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:O14617 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-1051639|uniprotkb:O00202|uniprotkb:O75262|uniprotkb:Q59HF5|uniprotkb:Q96G11|uniprotkb:Q9H3C6|ensembl:ENSP00000344055 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:ap3d1_human(display_long)|uniprotkb:AP-3 complex subunit delta(gene name synonym)|uniprotkb:Delta-adaptin(gene name synonym)|uniprotkb:AP3D1(gene name)|psi-mi:AP3D1(display_short)|uniprotkb:PRO0039(orf name)|uniprotkb:Adaptor-related protein complex 3 subunit delta-1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_003929.4|refseq:NP_001248755.1|ensembl:ENSG00000065000(gene)|ensembl:ENST00000345016(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016182"(synaptic vesicle budding from endosome)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0032438"(melanosome organization)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043195"(terminal bouton)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048007"(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0061088"(regulation of sequestering of zinc ion)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098830"(presynaptic endosome)|go:"GO:0098943"(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR010474(Bovine leukaemia virus receptor)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017105(Adaptor protein complex AP-3, delta subunit)|mint:O14617|rcsb pdb:4AFI|dip:DIP-46793N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:vw6bWz07cMYuwATlyDgx14oXzKY9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q9UL54 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-352832|ensembl:ENSP00000310094|uniprotkb:O94957|uniprotkb:Q6UW73|uniprotkb:Q7LC09|uniprotkb:Q9NSW2|uniprotkb:B2RN35|uniprotkb:A5PKY1|uniprotkb:A7MCZ2|uniprotkb:B7ZM88 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:taok2_human(display_long)|uniprotkb:TAOK2(gene name)|psi-mi:TAOK2(display_short)|uniprotkb:KIAA0881(gene name synonym)|uniprotkb:MAP3K17(gene name synonym)|uniprotkb:PSK(gene name synonym)|uniprotkb:PSK1(gene name synonym)|uniprotkb:UNQ2971/PRO7431(orf name)|uniprotkb:Prostate-derived sterile 20-like kinase 1(gene name synonym)|uniprotkb:Thousand and one amino acid protein kinase 2(gene name synonym)|uniprotkb:Kinase from chicken homolog C(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030424"(axon)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038191"(neuropilin binding)|go:"GO:0007409"(axonogenesis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0048156"(tau protein binding)|go:"GO:0043235"(receptor complex)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0106311"|go:"GO:0150019"(basal dendrite morphogenesis)|go:"GO:0150020"(basal dendrite arborization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0044295"(axonal growth cone)|mint:Q9UL54|go:"GO:0046330"(positive regulation of JNK cascade)|ensembl:ENSG00000149930(gene)|ensembl:ENST00000308893(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|refseq:NP_004774.1|refseq:NP_057235.2|refseq:NP_001238972.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:aA9reWZMb8l6Ziy+jyX5bbTD6vE9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:O95819 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-2511133|intact:EBI-28985706|ensembl:ENSP00000314363|uniprotkb:Q9NST7|uniprotkb:O75172|uniprotkb:E7ESS2 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:m4k4_human(display_long)|uniprotkb:MAP4K4(gene name)|psi-mi:MAP4K4(display_short)|uniprotkb:HGK(gene name synonym)|uniprotkb:KIAA0687(gene name synonym)|uniprotkb:NIK(gene name synonym)|uniprotkb:MAPK/ERK kinase kinase kinase 4(gene name synonym)|uniprotkb:HPK/GCK-like kinase HGK(gene name synonym)|uniprotkb:Nck-interacting kinase(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_663719.2|ensembl:ENST00000347699(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008017"(microtubule binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032014"(positive regulation of ARF protein signal transduction)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070571"(negative regulation of neuron projection regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O95819|rcsb pdb:4OBO|rcsb pdb:4OBP|rcsb pdb:4OBQ|rcsb pdb:4RVT|rcsb pdb:4U3Y|rcsb pdb:4U3Z|rcsb pdb:4U40|rcsb pdb:4U41|rcsb pdb:4U42|rcsb pdb:4U43|rcsb pdb:4U44|rcsb pdb:4U45|rcsb pdb:4ZK5|rcsb pdb:4ZP5|rcsb pdb:5DI1|rcsb pdb:5J95|rcsb pdb:5W5Q|reactome:R-HSA-2559580|ensembl:ENSG00000071054(gene)|refseq:NP_001229488.1|refseq:NP_004825.3|refseq:NP_663720.1|ensembl:ENSP00000314363|ensembl:ENST00000350878|ensembl:ENSP00000343658|ensembl:ENST00000634702|ensembl:ENSP00000489579 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:wEXGp6vM4HhwldyeQJKvEdilMpQ9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84008 uniprotkb:Q86UP2 intact:EBI-22302424|ensemblbacteria:AAC67595 intact:EBI-359761|uniprotkb:Q13999|uniprotkb:Q14707|uniprotkb:Q15387|uniprotkb:Q86W57|ensembl:ENSP00000378725|ensembl:ENSP00000432149|uniprotkb:Q17RZ5|uniprotkb:B4DZ88|uniprotkb:Q5GGW3 psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name) psi-mi:ktn1_human(display_long)|uniprotkb:KTN1(gene name)|psi-mi:KTN1(display_short)|uniprotkb:CG1(gene name synonym)|uniprotkb:KIAA0004(gene name synonym)|uniprotkb:Kinesin receptor(gene name synonym)|uniprotkb:CG-1 antigen(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302433|imex:IM-27647-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67595(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_005(gene)|mint:O84008|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355 refseq:NP_001072989.1|refseq:NP_004977.2|ensembl:ENSG00000126777(gene)|ensembl:ENST00000395314(transcript)|ensembl:ENST00000459737(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045296"(cadherin binding)|interpro:IPR007794(Ribosome receptor lysine or proline rich)|interpro:IPR024854|mint:Q86UP2|refseq:XP_011535053.1|refseq:XP_011535055.1|reactome:R-HSA-381426|reactome:R-HSA-5625970|reactome:R-HSA-8957275|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9696264|reactome:R-HSA-9696270|refseq:NP_001072990.1|refseq:NP_001257943.1|refseq:XP_006720201.1|refseq:XP_006720202.1|refseq:XP_016876767.1|refseq:XP_016876771.1|refseq:XP_016876772.1|dip:DIP-27585N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561 rogid:paZIiw7G2n1qUQ91xj5zi8x1Oxc9606 rigid:7TndZyzY0JX+R9bLeIRY1AfuzEw false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84009 uniprotkb:Q04917 intact:EBI-22302493|ensemblbacteria:AAC67596 intact:EBI-306940|ensembl:ENSP00000248975|intact:EBI-11759595 psi-mi:y006_chltr(display_long)|uniprotkb:CT_006(locus name) psi-mi:1433f_human(display_long)|uniprotkb:YWHAH(gene name)|psi-mi:YWHAH(display_short)|uniprotkb:YWHA1(gene name synonym)|uniprotkb:Protein AS1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302502|imex:IM-27647-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67596(transcript)|ensemblbacteria:CT_006(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:O84009|refseq:NP_219508.1|refseq:WP_009871352.1|interpro:IPR035358 go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:Q04917|rcsb pdb:2C63|rcsb pdb:2C74|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|ensembl:ENSG00000128245(gene)|ensembl:ENST00000248975(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_003396.1|dip:DIP-27566N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:F8nnTiew8jgaGltw+2w6cxGEHjk272561 rogid:VhFYPSsW3IRC388FTlmwwN37HnU9606 rigid:YXjQyhmENVJ/gaPUU8GMPTpPKbY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84009 uniprotkb:P31946 intact:EBI-22302493|ensemblbacteria:AAC67596 intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930 psi-mi:y006_chltr(display_long)|uniprotkb:CT_006(locus name) psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302502|imex:IM-27647-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67596(transcript)|ensemblbacteria:CT_006(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:O84009|refseq:NP_219508.1|refseq:WP_009871352.1|interpro:IPR035358 refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:F8nnTiew8jgaGltw+2w6cxGEHjk272561 rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606 rigid:YXjQyhmENVJ/gaPUU8GMPTpPKbY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84009 uniprotkb:P61981 intact:EBI-22302493|ensemblbacteria:AAC67596 intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330 psi-mi:y006_chltr(display_long)|uniprotkb:CT_006(locus name) psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302502|imex:IM-27647-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67596(transcript)|ensemblbacteria:CT_006(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:O84009|refseq:NP_219508.1|refseq:WP_009871352.1|interpro:IPR035358 refseq:NP_036611.2|ensembl:ENSG00000170027(gene)|ensembl:ENST00000307630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6A5S|rcsb pdb:6BYJ|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|dip:DIP-33406N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:F8nnTiew8jgaGltw+2w6cxGEHjk272561 rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606 rigid:YXjQyhmENVJ/gaPUU8GMPTpPKbY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84009 uniprotkb:Q13308 intact:EBI-22302493|ensemblbacteria:AAC67596 intact:EBI-2803245|uniprotkb:Q8NFA6|uniprotkb:Q5T650|uniprotkb:Q8NFA8|uniprotkb:Q13417|uniprotkb:Q6IQ54|uniprotkb:Q8NFA5|uniprotkb:Q8NFA7|uniprotkb:A8K974|uniprotkb:B7Z477|uniprotkb:E9PFZ5|ensembl:ENSP00000230419 psi-mi:y006_chltr(display_long)|uniprotkb:CT_006(locus name) psi-mi:ptk7_human(display_long)|uniprotkb:CCK4(gene name synonym)|uniprotkb:Colon carcinoma kinase 4(gene name synonym)|uniprotkb:Protein-tyrosine kinase 7(gene name synonym)|uniprotkb:PTK7(gene name)|psi-mi:PTK7(display_short)|uniprotkb:Pseudo tyrosine kinase receptor 7(gene name synonym)|uniprotkb:Tyrosine-protein kinase-like 7(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302502|imex:IM-27647-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67596(transcript)|ensemblbacteria:CT_006(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:O84009|refseq:NP_219508.1|refseq:WP_009871352.1|interpro:IPR035358 refseq:NP_001257327.1|refseq:NP_002812.2|refseq:NP_690619.1|refseq:NP_690620.1|refseq:NP_690621.1|ensembl:ENSG00000112655(gene)|ensembl:ENST00000230419(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003401"(axis elongation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016477"(cell migration)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042060"(wound healing)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060026"(convergent extension)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1904929"(coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:Q13308|rcsb pdb:6VG3 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:F8nnTiew8jgaGltw+2w6cxGEHjk272561 rogid:O4L3LFD0WvN1hDb1abqVBbW1gis9606 rigid:YXjQyhmENVJ/gaPUU8GMPTpPKbY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14967 uniprotkb:O84039 intact:EBI-3907005|uniprotkb:D3DNY8|uniprotkb:B3KS90|uniprotkb:B4DXV8|ensembl:ENSP00000326699|ensembl:ENSP00000392782 intact:EBI-22302511|ensemblbacteria:AAC67626 psi-mi:clgn_human(display_long)|uniprotkb:CLGN(gene name)|psi-mi:CLGN(display_short) psi-mi:y036_chltr(display_long)|uniprotkb:CT_036(locus name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:272561(chltr)|taxid:272561(chltr) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302519|imex:IM-27647-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124147.1|refseq:NP_004353.1|ensembl:ENSG00000153132(gene)|ensembl:ENST00000325617(transcript)|ensembl:ENST00000414773(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007338"(single fertilization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:O14967 ensemblbacteria:AAC67626(transcript)|ensemblbacteria:CT_036(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:O84039|refseq:NP_219538.1|refseq:WP_010724994.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:Akb2XoiNjob34njC2erE11yg80w9606 rogid:D6ARk/Mp8W+Kpqkk3xLQyADkav4272561 rigid:WkN+a6UmB0RXBY/DXr/edt8fftA false - binding-associated region:52-403|strep tag:c-c - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84061 uniprotkb:Q9Y5J9 intact:EBI-22302545|ensemblbacteria:AAC67649 intact:EBI-1049085|uniprotkb:Q3KQS9|uniprotkb:Q9UN04|uniprotkb:B0YJA5|ensembl:ENSP00000422122 psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name) psi-mi:tim8b_human(display_long)|uniprotkb:Deafness dystonia protein 2(gene name synonym)|uniprotkb:DDP-like protein(gene name synonym)|uniprotkb:TIM8B(gene name synonym)|uniprotkb:TIMM8B(gene name)|psi-mi:TIMM8B(display_short)|uniprotkb:DDP2(gene name synonym)|uniprotkb:DDPL(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302553|imex:IM-27647-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67649(transcript)|ensemblbacteria:CT_058(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84061|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing) refseq:NP_036591.2|ensembl:ENSG00000150779(gene)|ensembl:ENST00000504148(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0140318"(protein transporter activity)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:Q9Y5J9|reactome:R-HSA-1268020 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561 rogid:7DK/1BIkwyl9KMIgEFWqRhZn2ZE9606 rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw false strep tag:c-c|binding-associated region:57-367 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84061 uniprotkb:O60220 intact:EBI-22302545|ensemblbacteria:AAC67649 intact:EBI-1049822|uniprotkb:Q6IRW6|uniprotkb:B2R5A6|ensembl:ENSP00000361993 psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name) psi-mi:tim8a_human(display_long)|uniprotkb:Deafness dystonia protein 1(gene name synonym)|uniprotkb:X-linked deafness dystonia protein(gene name synonym)|uniprotkb:TIMM8A(gene name)|psi-mi:TIMM8A(display_short)|uniprotkb:DDP(gene name synonym)|uniprotkb:DDP1(gene name synonym)|uniprotkb:TIM8A(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302553|imex:IM-27647-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67649(transcript)|ensemblbacteria:CT_058(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84061|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing) refseq:NP_004076.1|reactome:R-HSA-1268020|ensembl:ENSG00000126953(gene)|ensembl:ENST00000372902(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007399"(nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:O60220 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561 rogid:v01DxxXFU24eNjL3zVBvqQP9zA49606 rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw false strep tag:c-c|binding-associated region:57-367 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84061 uniprotkb:Q15165 intact:EBI-22302545|ensemblbacteria:AAC67649 intact:EBI-3909798|ensembl:ENSP00000222572|ensembl:ENSP00000488838|uniprotkb:O15114|uniprotkb:B4DJD5|uniprotkb:Q5FBX7|uniprotkb:O15115|uniprotkb:B2RCP9|uniprotkb:Q86YL0|uniprotkb:O75856|uniprotkb:A4D1H7|intact:EBI-10966394 psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name) psi-mi:pon2_human(display_long)|uniprotkb:PON2(gene name)|psi-mi:PON2(display_short)|uniprotkb:Aromatic esterase 2(gene name synonym)|uniprotkb:Serum aryldialkylphosphatase 2(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302553|imex:IM-27647-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67649(transcript)|ensemblbacteria:CT_058(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84061|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing) ensembl:ENSG00000105854(gene)|ensembl:ENST00000222572(transcript)|ensembl:ENST00000633531(transcript)|go:"GO:0004064"(arylesterase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009636"(response to toxic substance)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0102007"(acyl-L-homoserine-lactone lactonohydrolase activity)|interpro:IPR002640(Arylesterase)|interpro:IPR008364(Paraoxonase2)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|mint:Q15165|reactome:R-HSA-2142688|refseq:NP_000296.2|dip:DIP-61136N|refseq:NP_001018171.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561 rogid:9zE87aut0R8eYxaXM+HgYsJxLYI9606 rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw false strep tag:c-c|binding-associated region:57-367 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84061 uniprotkb:P07237 intact:EBI-22302545|ensemblbacteria:AAC67649 intact:EBI-395883|uniprotkb:P30037|uniprotkb:P32079|uniprotkb:Q15205|uniprotkb:Q6LDE5|uniprotkb:B2RDQ2|ensembl:ENSP00000327801 psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name) psi-mi:pdia1_human(display_long)|uniprotkb:P4HB(gene name)|psi-mi:P4HB(display_short)|uniprotkb:PDI(gene name synonym)|uniprotkb:PDIA1(gene name synonym)|uniprotkb:PO4DB(gene name synonym)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:p55(gene name synonym)|uniprotkb:ERBA2L(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302553|imex:IM-27647-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67649(transcript)|ensemblbacteria:CT_058(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84061|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing) refseq:NP_000909.2|ensembl:ENSG00000185624(gene)|ensembl:ENST00000331483(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0038155"(interleukin-23-mediated signaling pathway)|go:"GO:0042470"(melanosome)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P07237|rcsb pdb:1BJX|rcsb pdb:1MEK|rcsb pdb:1X5C|rcsb pdb:2BJX|rcsb pdb:2K18|rcsb pdb:3BJ5|rcsb pdb:3UEM|rcsb pdb:4EKZ|rcsb pdb:4EL1|rcsb pdb:4JU5|rcsb pdb:6I7S|reactome:R-HSA-1650814|reactome:R-HSA-3299685|reactome:R-HSA-381426|reactome:R-HSA-5358346|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-9020591|reactome:R-HSA-9020933|dip:DIP-32979N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561 rogid:rh0B38TSfTX+lvU5OyBwEbVndFA9606 rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw false strep tag:c-c|binding-associated region:57-367 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84061 uniprotkb:O14967 intact:EBI-22302545|ensemblbacteria:AAC67649 intact:EBI-3907005|uniprotkb:D3DNY8|uniprotkb:B3KS90|uniprotkb:B4DXV8|ensembl:ENSP00000326699|ensembl:ENSP00000392782 psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name) psi-mi:clgn_human(display_long)|uniprotkb:CLGN(gene name)|psi-mi:CLGN(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302553|imex:IM-27647-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67649(transcript)|ensemblbacteria:CT_058(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84061|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing) refseq:NP_001124147.1|refseq:NP_004353.1|ensembl:ENSG00000153132(gene)|ensembl:ENST00000325617(transcript)|ensembl:ENST00000414773(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007338"(single fertilization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:O14967 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561 rogid:Akb2XoiNjob34njC2erE11yg80w9606 rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw false strep tag:c-c|binding-associated region:57-367 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84061 uniprotkb:Q9NYU2 intact:EBI-22302545|ensemblbacteria:AAC67649 intact:EBI-1056389|uniprotkb:Q53SL3|uniprotkb:Q8IW30|uniprotkb:Q9H8I4|uniprotkb:Q53QP2|ensembl:ENSP00000259253 psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name) psi-mi:uggg1_human(display_long)|uniprotkb:UGGT1(gene name)|psi-mi:UGGT1(display_short)|uniprotkb:GT(gene name synonym)|uniprotkb:UGGT(gene name synonym)|uniprotkb:UGT1(gene name synonym)|uniprotkb:UGTR(gene name synonym)|uniprotkb:UDP-glucose ceramide glucosyltransferase-like 1(gene name synonym)|uniprotkb:"UDP--Glc:glycoprotein glucosyltransferase"(gene name synonym)|uniprotkb:UGCGL1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302553|imex:IM-27647-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67649(transcript)|ensemblbacteria:CT_058(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84061|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing) refseq:NP_064505.1|ensembl:ENSG00000136731(gene)|ensembl:ENST00000259253(transcript)|go:"GO:0003980"("UDP-glucose:glycoprotein glucosyltransferase activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051084"('de novo' posttranslational protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR009448("UDP-glucose:Glycoprotein Glucosyltransferase")|interpro:IPR029044|interpro:IPR040497|interpro:IPR040525|interpro:IPR040692|interpro:IPR040693|interpro:IPR040694|mint:Q9NYU2|reactome:R-HSA-901032 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561 rogid:WgjCB9PJiHtQXloeFEerSmIoQU89606 rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw false strep tag:c-c|binding-associated region:57-367 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84061 uniprotkb:O60613 intact:EBI-22302545|ensemblbacteria:AAC67649 intact:EBI-1052797|uniprotkb:Q4GZG7|uniprotkb:Q8WU00|uniprotkb:Q9BS64|uniprotkb:Q9GZW0|uniprotkb:Q9NR01|ensembl:ENSP00000328729|uniprotkb:A0A0B4J1S4 psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name) psi-mi:sep15_human(display_long)|uniprotkb:SELENOF(gene name)|psi-mi:SELENOF(display_short)|uniprotkb:15 kDa selenoprotein(gene name synonym)|uniprotkb:SEP15(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302553|imex:IM-27647-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67649(transcript)|ensemblbacteria:CT_058(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84061|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing) refseq:NP_004252.2|refseq:NP_976086.1|mint:O60613|interpro:IPR039992|ensembl:ENSG00000183291(gene)|ensembl:ENST00000331835(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0051084"('de novo' posttranslational protein folding)|interpro:IPR014912(Sep15/SelM redox)|interpro:IPR036249|interpro:IPR038219 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561 rogid:O+C59EK6dpYLDbHWrJT10RtGus89606 rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw false strep tag:c-c|binding-associated region:57-367 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84061 uniprotkb:P55345 intact:EBI-22302545|ensemblbacteria:AAC67649 intact:EBI-78458|uniprotkb:P78350|uniprotkb:Q9BW15|uniprotkb:Q9UMC2|ensembl:ENSP00000347906|ensembl:ENSP00000380759|ensembl:ENSP00000380760|uniprotkb:Q6FHF0|uniprotkb:Q99781|uniprotkb:Q498Y5|uniprotkb:B7U630|uniprotkb:B7U631|uniprotkb:B7U632|uniprotkb:Q5U7D4 psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name) psi-mi:anm2_human(display_long)|uniprotkb:PRMT2(gene name)|psi-mi:PRMT2(display_short)|uniprotkb:HMT1(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT2(gene name synonym)|uniprotkb:HRMT1L1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302553|imex:IM-27647-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67649(transcript)|ensemblbacteria:CT_058(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84061|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing) ensembl:ENSG00000160310(gene)|ensembl:ENST00000355680(transcript)|ensembl:ENST00000397637(transcript)|ensembl:ENST00000397638(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048588"(developmental cell growth)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR007848(Methyltransferase small)|interpro:IPR025799|interpro:IPR029063|interpro:IPR036028|mint:P55345|rcsb pdb:1X2P|refseq:NP_001526.2|refseq:NP_996845.1|refseq:NP_001273605.1|refseq:NP_001273606.1|refseq:NP_001273607.1|refseq:NP_001229794.1|refseq:NP_001229793.1|refseq:XP_005261168.1|refseq:NP_001229795.1|refseq:XP_006724061.1|refseq:XP_006724063.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561 rogid:+xna8Cy+5sQWV6hvKfg4rNrQKBw9606 rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw false strep tag:c-c|binding-associated region:57-367 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84061 uniprotkb:Q6NUQ4 intact:EBI-22302545|ensemblbacteria:AAC67649 intact:EBI-372318|uniprotkb:A6NNF2|uniprotkb:Q53SW1|uniprotkb:Q69YH4|uniprotkb:Q8WZ37|uniprotkb:Q9NXH2|uniprotkb:Q8NC45|uniprotkb:B3KUI9|uniprotkb:B5MCD8|ensembl:ENSP00000238788|ensembl:ENSP00000319469|uniprotkb:D6W547 psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name) psi-mi:tm214_human(display_long)|uniprotkb:TMEM214(gene name)|psi-mi:TMEM214(display_short)|uniprotkb:PP446(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302553|imex:IM-27647-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67649(transcript)|ensemblbacteria:CT_058(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84061|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing) ensembl:ENSG00000119777(gene)|ensembl:ENST00000238788(transcript)|ensembl:ENST00000321326(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR019308|mint:Q6NUQ4|refseq:NP_001077059.1|refseq:NP_060197.4 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561 rogid:Yx4jp39AqeiXqOJVzMMRqRgk8449606 rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw false strep tag:c-c|binding-associated region:57-367 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84061 uniprotkb:Q32P28 intact:EBI-22302545|ensemblbacteria:AAC67649 intact:EBI-396328|uniprotkb:Q96SK8|uniprotkb:Q7KZR4|uniprotkb:Q96BR8|uniprotkb:Q96SL5|uniprotkb:Q96SN3|uniprotkb:Q9H6K3|uniprotkb:Q9HC86|uniprotkb:Q9HC87|intact:EBI-2555416|ensembl:ENSP00000296388 psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name) psi-mi:p3h1_human(display_long)|uniprotkb:P3H1(gene name)|psi-mi:P3H1(display_short)|uniprotkb:GROS1(gene name synonym)|uniprotkb:Growth suppressor 1(gene name synonym)|uniprotkb:LEPRE1(gene name synonym)|uniprotkb:Leucine- and proline-enriched proteoglycan 1(gene name synonym)|uniprotkb:PSEC0109(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302553|imex:IM-27647-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67649(transcript)|ensemblbacteria:CT_058(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84061|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing) refseq:NP_001139761.1|refseq:NP_001230175.1|refseq:NP_071751.3|ensembl:ENSG00000117385(gene)|ensembl:ENST00000296388(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0019797"(procollagen-proline 3-dioxygenase activity)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050821"(protein stabilization)|go:"GO:0060348"(bone development)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901874"(negative regulation of post-translational protein modification)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR039575|interpro:IPR039837|mint:Q32P28|reactome:R-HSA-1650814 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561 rogid:L3euuYyawz69NXv4u6baW/ceVdU9606 rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw false strep tag:c-c|binding-associated region:57-367 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84061 uniprotkb:Q8IXB1 intact:EBI-22302545|ensemblbacteria:AAC67649 intact:EBI-2949763|ensembl:ENSP00000264065|uniprotkb:Q53QT7|uniprotkb:Q6UWZ6|uniprotkb:Q96K44|uniprotkb:Q8NC82|uniprotkb:Q86T61|uniprotkb:Q9NSY6|uniprotkb:Q17RJ6|uniprotkb:Q8TD87|uniprotkb:Q96K54|uniprotkb:Q96K38|uniprotkb:Q4ZG06|uniprotkb:Q3B7W8 psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name) psi-mi:djc10_human(display_long)|uniprotkb:DNAJC10(gene name)|psi-mi:DNAJC10(display_short)|uniprotkb:ERDJ5(gene name synonym)|uniprotkb:Macrothioredoxin(gene name synonym)|uniprotkb:UNQ495/PRO1012(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 5(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302553|imex:IM-27647-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67649(transcript)|ensemblbacteria:CT_058(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84061|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing) ensembl:ENSG00000077232(gene)|ensembl:ENST00000264065(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0016020"(membrane)|go:"GO:0016671"(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR021170|interpro:IPR035673|interpro:IPR035674|interpro:IPR036249|interpro:IPR036869|mint:Q8IXB1|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|refseq:NP_061854.1|refseq:NP_001258510.1|dip:DIP-48947N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561 rogid:sD/pp49jws0LrBjwCxQmZqzfR9U9606 rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw false strep tag:c-c|binding-associated region:57-367 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6DD88 uniprotkb:O84137 intact:EBI-6165882|ensembl:ENSP00000381844|uniprotkb:Q8N7W5|uniprotkb:Q9H8Q5|uniprotkb:Q9UFL1 intact:EBI-22302573|ensemblbacteria:AAC67726 psi-mi:atla3_human(display_long)|uniprotkb:ATL3(gene name)|psi-mi:ATL3(display_short) psi-mi:o84137_chltr(display_long)|uniprotkb:CT_135(locus name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:272561(chltr)|taxid:272561(chltr) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302580|imex:IM-27647-83 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1903373"(positive regulation of endoplasmic reticulum tubular network organization)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q6DD88|rcsb pdb:5VGR|rcsb pdb:6XJO|go:"GO:0007030"(Golgi organization)|ensembl:ENSG00000184743(gene)|ensembl:ENST00000398868(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|refseq:NP_001276977.1|refseq:NP_056274.3 ensemblbacteria:AAC67726(transcript)|ensemblbacteria:CT_135(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84137|refseq:NP_219638.1|refseq:WP_009873048.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:9vgpZvUg5aFAZyNiZ2pdEPn/J7o9606 rogid:8IsEuju3fvTl5kH9oZp4jHGWyOs272561 rigid:X/Z6tpoX+1CTQuIPV553NtW7WGg false - binding-associated region:57-360|strep tag:c-c - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6DD88 uniprotkb:Q6P1K2 intact:EBI-6165882|ensembl:ENSP00000381844|uniprotkb:Q8N7W5|uniprotkb:Q9H8Q5|uniprotkb:Q9UFL1 intact:EBI-713832|uniprotkb:Q5TCJ8|uniprotkb:Q5TCJ9|uniprotkb:Q5TCK3|uniprotkb:Q69YZ9|uniprotkb:Q6PHR4|uniprotkb:Q86VJ6|uniprotkb:Q8N4T6|uniprotkb:Q9UBQ3|uniprotkb:A8K0C5|intact:EBI-2554676|uniprotkb:Q5TCK0|ensembl:ENSP00000357260|uniprotkb:Q5TCK1|uniprotkb:Q6ZVE6 psi-mi:atla3_human(display_long)|uniprotkb:ATL3(gene name)|psi-mi:ATL3(display_short) psi-mi:pmf1_human(display_long)|uniprotkb:PMF1(gene name)|psi-mi:PMF1(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302580|imex:IM-27647-83 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1903373"(positive regulation of endoplasmic reticulum tubular network organization)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q6DD88|rcsb pdb:5VGR|rcsb pdb:6XJO|go:"GO:0007030"(Golgi organization)|ensembl:ENSG00000184743(gene)|ensembl:ENST00000398868(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|refseq:NP_001276977.1|refseq:NP_056274.3 ensembl:ENSG00000160783(gene)|ensembl:ENST00000368277(transcript)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0051301"(cell division)|interpro:IPR007128(Nnf1)|mint:Q6P1K2|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001186582.1|refseq:NP_001186583.1|refseq:NP_001186590.1|refseq:NP_001186592.1|refseq:NP_009152.2 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:9vgpZvUg5aFAZyNiZ2pdEPn/J7o9606 rogid:76xPGmFgI3Pt1gsZMb3aD4hpPWM9606 rigid:X/Z6tpoX+1CTQuIPV553NtW7WGg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6DD88 uniprotkb:Q9UI12 intact:EBI-6165882|ensembl:ENSP00000381844|uniprotkb:Q8N7W5|uniprotkb:Q9H8Q5|uniprotkb:Q9UFL1 intact:EBI-724719|uniprotkb:Q6PK44|uniprotkb:Q9H3E3|uniprotkb:Q9Y300|uniprotkb:B3KMR0|ensembl:ENSP00000352522|ensembl:ENSP00000379995 psi-mi:atla3_human(display_long)|uniprotkb:ATL3(gene name)|psi-mi:ATL3(display_short) psi-mi:vath_human(display_long)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 50/57 kDa subunits(gene name synonym)|uniprotkb:Vacuolar proton pump subunit SFD(gene name synonym)|uniprotkb:Protein VMA13 homolog(gene name synonym)|uniprotkb:Nef-binding protein 1(gene name synonym)|uniprotkb:ATP6V1H(gene name)|psi-mi:ATP6V1H(display_short)|uniprotkb:CGI-11(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302580|imex:IM-27647-83 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1903373"(positive regulation of endoplasmic reticulum tubular network organization)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q6DD88|rcsb pdb:5VGR|rcsb pdb:6XJO|go:"GO:0007030"(Golgi organization)|ensembl:ENSG00000184743(gene)|ensembl:ENST00000398868(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|refseq:NP_001276977.1|refseq:NP_056274.3 refseq:NP_057025.2|refseq:NP_998784.1|refseq:NP_998785.1|ensembl:ENSG00000047249(gene)|ensembl:ENST00000359530(transcript)|ensembl:ENST00000396774(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|mint:Q9UI12|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-167590|reactome:R-HSA-182218|reactome:R-HSA-917977|reactome:R-HSA-9636467|reactome:R-HSA-9639288|reactome:R-HSA-983712|reactome:R-HSA-77387|refseq:XP_006716518.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:9vgpZvUg5aFAZyNiZ2pdEPn/J7o9606 rogid:n2fyA8m4qnlSmS3R1xBBE3RRV9A9606 rigid:X/Z6tpoX+1CTQuIPV553NtW7WGg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6DD88 uniprotkb:Q9C0E2 intact:EBI-6165882|ensembl:ENSP00000381844|uniprotkb:Q8N7W5|uniprotkb:Q9H8Q5|uniprotkb:Q9UFL1 intact:EBI-1044855|uniprotkb:Q5VUZ5|uniprotkb:Q9H934|uniprotkb:Q8N3V6|ensembl:ENSP00000255305 psi-mi:atla3_human(display_long)|uniprotkb:ATL3(gene name)|psi-mi:ATL3(display_short) psi-mi:xpo4_human(display_long)|uniprotkb:XPO4(gene name)|psi-mi:XPO4(display_short)|uniprotkb:KIAA1721(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302580|imex:IM-27647-83 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1903373"(positive regulation of endoplasmic reticulum tubular network organization)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q6DD88|rcsb pdb:5VGR|rcsb pdb:6XJO|go:"GO:0007030"(Golgi organization)|ensembl:ENSG00000184743(gene)|ensembl:ENST00000398868(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|refseq:NP_001276977.1|refseq:NP_056274.3 refseq:NP_071904.4|ensembl:ENSG00000132953(gene)|ensembl:ENST00000255305(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0046827"(positive regulation of protein export from nucleus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR044189|mint:Q9C0E2|go:"GO:0005643"(nuclear pore) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:9vgpZvUg5aFAZyNiZ2pdEPn/J7o9606 rogid:+7lQFg9CBnDLFt9rqjLb//HPJnQ9606 rigid:X/Z6tpoX+1CTQuIPV553NtW7WGg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84166 uniprotkb:P61163 intact:EBI-22302591|ensemblbacteria:AAC67755 intact:EBI-774234|uniprotkb:P42024|uniprotkb:B2R6B0|ensembl:ENSP00000358921 psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name) psi-mi:actz_human(display_long)|uniprotkb:Centrosome-associated actin homolog(gene name synonym)|uniprotkb:Actin-RPV(gene name synonym)|uniprotkb:ARP1(gene name synonym)|uniprotkb:ACTR1A(gene name)|psi-mi:ACTR1A(display_short)|uniprotkb:CTRN1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302598|imex:IM-27647-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67755(transcript)|ensemblbacteria:CT_164(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84166|refseq:NP_219667.1|refseq:WP_010725105.1 refseq:NP_005727.1|ensembl:ENSG00000138107(gene)|ensembl:ENST00000369905(transcript)|go:"GO:0002177"(manchette)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P61163|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561 rogid:aJHKOSj1qmZ7Pk8aZAyWWd8DEdw9606 rigid:pYiXtRE8pFAP+nXrs41YP6kmJ6o false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84166 uniprotkb:Q9BTE1 intact:EBI-22302591|ensemblbacteria:AAC67755 intact:EBI-747324|uniprotkb:H3BN51|uniprotkb:A8K9X8|uniprotkb:H3BQA4|ensembl:ENSP00000300087 psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name) psi-mi:dctn5_human(display_long)|uniprotkb:Dynactin subunit p25(gene name synonym)|uniprotkb:DCTN5(gene name)|psi-mi:DCTN5(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302598|imex:IM-27647-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67755(transcript)|ensemblbacteria:CT_164(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84166|refseq:NP_219667.1|refseq:WP_010725105.1 refseq:NP_115875.1|refseq:NP_001186672.1|refseq:NP_001185940.1|ensembl:ENSG00000166847(gene)|ensembl:ENST00000300087(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035904"(aorta development)|go:"GO:0060976"(coronary vasculature development)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR011004(Trimeric LpxA-like)|mint:Q9BTE1|rcsb pdb:5NW4|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561 rogid:/aCDlJJ8PO7etMT4aZxg1i5WtYE9606 rigid:pYiXtRE8pFAP+nXrs41YP6kmJ6o false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84166 uniprotkb:O75935 intact:EBI-22302591|ensemblbacteria:AAC67755 intact:EBI-347442|uniprotkb:A6NII7|uniprotkb:Q5T1I5|uniprotkb:Q5T1I7|uniprotkb:Q5T8G3|uniprotkb:Q9BPU8|uniprotkb:B2RBM5|ensembl:ENSP00000259632 psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name) psi-mi:dctn3_human(display_long)|uniprotkb:DCTN22(gene name synonym)|uniprotkb:DCTN3(gene name)|psi-mi:DCTN3(display_short)|uniprotkb:Dynactin complex subunit 22 kDa subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302598|imex:IM-27647-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67755(transcript)|ensemblbacteria:CT_164(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84166|refseq:NP_219667.1|refseq:WP_010725105.1 refseq:NP_009165.1|refseq:NP_077324.1|ensembl:ENSG00000137100(gene)|ensembl:ENST00000259632(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR009991(Dynactin subunit p22)|mint:O75935|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|refseq:NP_001268354.1|refseq:NP_001268355.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561 rogid:KPLiGDMa0KR/H31QtEdl2YiwYzk9606 rigid:pYiXtRE8pFAP+nXrs41YP6kmJ6o false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84166 uniprotkb:O00399 intact:EBI-22302591|ensemblbacteria:AAC67755 intact:EBI-2559415|uniprotkb:B2RAC1|ensembl:ENSP00000221114 psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name) psi-mi:dctn6_human(display_long)|uniprotkb:DCTN6(gene name)|psi-mi:DCTN6(display_short)|uniprotkb:WS3(gene name synonym)|uniprotkb:Dynactin subunit p27(gene name synonym)|uniprotkb:Protein WS-3(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302598|imex:IM-27647-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67755(transcript)|ensemblbacteria:CT_164(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84166|refseq:NP_219667.1|refseq:WP_010725105.1 refseq:NP_006562.1|ensembl:ENSG00000104671(gene)|ensembl:ENST00000221114(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR027777|mint:O00399|rcsb pdb:3TV0|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561 rogid:+35O26TEIL5l1I7XrNJcl6BA77c9606 rigid:pYiXtRE8pFAP+nXrs41YP6kmJ6o false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84166 uniprotkb:Q14192 intact:EBI-22302591|ensemblbacteria:AAC67755 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name) psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302598|imex:IM-27647-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67755(transcript)|ensemblbacteria:CT_164(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84166|refseq:NP_219667.1|refseq:WP_010725105.1 ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 rigid:pYiXtRE8pFAP+nXrs41YP6kmJ6o false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84166 uniprotkb:Q12792 intact:EBI-22302591|ensemblbacteria:AAC67755 intact:EBI-1056675|uniprotkb:Q6NUK9|uniprotkb:A8K5A8|uniprotkb:Q59G07|uniprotkb:Q5U0B1|uniprotkb:Q6FHJ1|uniprotkb:Q6FHL6|uniprotkb:Q86XL6|uniprotkb:Q8TCD3|ensembl:ENSP00000378886|uniprotkb:B3KXS6|uniprotkb:B4DLX9 psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name) psi-mi:twf1_human(display_long)|uniprotkb:TWF1(gene name)|psi-mi:TWF1(display_short)|uniprotkb:PTK9(gene name synonym)|uniprotkb:Protein A6(gene name synonym)|uniprotkb:Protein tyrosine kinase 9(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302598|imex:IM-27647-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67755(transcript)|ensemblbacteria:CT_164(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84166|refseq:NP_219667.1|refseq:WP_010725105.1 ensembl:ENSG00000151239(gene)|ensembl:ENST00000395510(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030016"(myofibril)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043538"(regulation of actin phosphorylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|mint:Q12792|refseq:NP_001229326.1|refseq:NP_002813.3|rcsb pdb:7CCC|reactome:R-HSA-9013418|reactome:R-HSA-9662360|reactome:R-HSA-9662361 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561 rogid:5yv7DC8rsBmxmXtzv40wJ/U154c9606 rigid:pYiXtRE8pFAP+nXrs41YP6kmJ6o false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84166 uniprotkb:P42025 intact:EBI-22302591|ensemblbacteria:AAC67755 intact:EBI-367493|uniprotkb:Q53SK5|uniprotkb:Q9BRB7|uniprotkb:D3DVH2|ensembl:ENSP00000289228 psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name) psi-mi:acty_human(display_long)|uniprotkb:ACTR1B(gene name)|psi-mi:ACTR1B(display_short)|uniprotkb:Actin-related protein 1B(gene name synonym)|uniprotkb:CTRN2(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302598|imex:IM-27647-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67755(transcript)|ensemblbacteria:CT_164(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84166|refseq:NP_219667.1|refseq:WP_010725105.1 ensembl:ENSG00000115073(gene)|ensembl:ENST00000289228(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P42025|reactome:R-HSA-2132295|reactome:R-HSA-6798695|refseq:NP_005726.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561 rogid:FUpYgmLV3BdkZIlZGyC6L5kR+wE9606 rigid:pYiXtRE8pFAP+nXrs41YP6kmJ6o false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84166 uniprotkb:Q13561 intact:EBI-22302591|ensemblbacteria:AAC67755 intact:EBI-715074|uniprotkb:Q86YN2|uniprotkb:Q9BW17|uniprotkb:B2RBK5|ensembl:ENSP00000447824 psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name) psi-mi:dctn2_human(display_long)|uniprotkb:Dynactin complex 50 kDa subunit(gene name synonym)|uniprotkb:50 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:p50 dynamitin(gene name synonym)|uniprotkb:DCTN2(gene name)|psi-mi:DCTN2(display_short)|uniprotkb:DCTN50(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302598|imex:IM-27647-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67755(transcript)|ensemblbacteria:CT_164(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84166|refseq:NP_219667.1|refseq:WP_010725105.1 refseq:NP_006391.1|refseq:NP_001248341.1|refseq:NP_001248342.1|dip:DIP-37545N|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|ensembl:ENSG00000175203(gene)|ensembl:ENST00000548249(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030286"(dynein complex)|go:"GO:0030426"(growth cone)|go:"GO:0030507"(spectrin binding)|go:"GO:0031982"(vesicle)|go:"GO:0032402"(melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071539"(protein localization to centrosome)|interpro:IPR028133|mint:Q13561|reactome:R-HSA-2132295 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561 rogid:JrL5jUtArek+zqmCkPKomnjuSf09606 rigid:pYiXtRE8pFAP+nXrs41YP6kmJ6o false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84166 uniprotkb:Q9NZ32 intact:EBI-22302591|ensemblbacteria:AAC67755 intact:EBI-2559426|uniprotkb:Q9H9Y5|uniprotkb:Q9NWY2|ensembl:ENSP00000254286 psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name) psi-mi:arp10_human(display_long)|uniprotkb:ACTR10(gene name)|psi-mi:ACTR10(display_short)|uniprotkb:ACTR11(gene name synonym)|uniprotkb:ARP11(gene name synonym)|uniprotkb:Actin-related protein 11(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302598|imex:IM-27647-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67755(transcript)|ensemblbacteria:CT_164(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84166|refseq:NP_219667.1|refseq:WP_010725105.1 refseq:NP_060947.1|ensembl:ENSG00000131966(gene)|ensembl:ENST00000254286(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0098958"(retrograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004000(Actin/actin-like)|interpro:IPR027127|interpro:IPR043129|mint:Q9NZ32|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561 rogid:zP8oC2X4zksg1YC89SF2yerpa6I9606 rigid:pYiXtRE8pFAP+nXrs41YP6kmJ6o false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84166 uniprotkb:Q9UJW0 intact:EBI-22302591|ensemblbacteria:AAC67755 intact:EBI-2134033|uniprotkb:Q8TAN8|uniprotkb:D3DQH0|intact:EBI-2559420|uniprotkb:B3KWW0|uniprotkb:E5RGT5|ensembl:ENSP00000416968 psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name) psi-mi:dctn4_human(display_long)|uniprotkb:DCTN4(gene name)|psi-mi:DCTN4(display_short)|uniprotkb:Dynactin subunit p62(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302598|imex:IM-27647-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67755(transcript)|ensemblbacteria:CT_164(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84166|refseq:NP_219667.1|refseq:WP_010725105.1 refseq:XP_011535946.1|refseq:XP_011535947.1|refseq:NP_001129116.1|refseq:NP_057305.1|refseq:NP_001129115.1|ensembl:ENSG00000132912(gene)|ensembl:ENST00000447998(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0001725"(stress fiber)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005869"(dynactin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0030017"(sarcomere)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008603(Dynactin p62)|mint:Q9UJW0|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561 rogid:JradQZl06O4u9N3HH+cpvdP05RA9606 rigid:pYiXtRE8pFAP+nXrs41YP6kmJ6o false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84166 uniprotkb:Q14203 intact:EBI-22302591|ensemblbacteria:AAC67755 intact:EBI-724352|uniprotkb:O95296|uniprotkb:Q9BRM9|uniprotkb:Q9UIU1|intact:EBI-28971695|ensembl:ENSP00000487279|uniprotkb:Q9UIU2|uniprotkb:E9PGE1|uniprotkb:G5E9H4|uniprotkb:Q6IQ37|intact:EBI-2560059|uniprotkb:B4DM45|uniprotkb:E9PFS5|uniprotkb:A8MY36|intact:EBI-10962300 psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name) psi-mi:dctn1_human(display_long)|uniprotkb:DCTN1(gene name)|psi-mi:DCTN1(display_short)|uniprotkb:150 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:DAP-150(gene name synonym)|uniprotkb:p150-glued(gene name synonym)|uniprotkb:p135(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302598|imex:IM-27647-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67755(transcript)|ensemblbacteria:CT_164(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84166|refseq:NP_219667.1|refseq:WP_010725105.1 refseq:NP_001128512.1|refseq:NP_001128513.1|refseq:NP_001177766.1|refseq:NP_004073.2|refseq:NP_075408.1|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381038|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|reactome:R-HSA-380259|ensembl:ENSG00000204843(gene)|ensembl:ENST00000628224(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005938"(cell cortex)|go:"GO:0007097"(nuclear migration)|go:"GO:0007399"(nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048156"(tau protein binding)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061744"(motor behavior)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:0099738"(cell cortex region)|go:"GO:0120103"(centriolar subdistal appendage)|go:"GO:1904398"(positive regulation of neuromuscular junction development)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990535"(neuron projection maintenance)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|interpro:IPR036859|mint:Q14203|rcsb pdb:1TXQ|rcsb pdb:2COY|rcsb pdb:2HKN|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2HQH|rcsb pdb:3E2U|rcsb pdb:3TQ7|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|ensembl:ENST00000394003|ensembl:ENSP00000377571|ensembl:ENST00000409240|ensembl:ENSP00000386406|ensembl:ENST00000409438|ensembl:ENSP00000387270|ensembl:ENST00000409567|ensembl:ENSP00000386843|ensembl:ENSP00000487279|ensembl:ENST00000633691|ensembl:ENSP00000487724|refseq:NP_001177765.1|dip:DIP-31365N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561 rogid:PKchWdLWycCErGzSVMXq/xCQJRM9606 rigid:pYiXtRE8pFAP+nXrs41YP6kmJ6o false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84166 uniprotkb:P08519 intact:EBI-22302591|ensemblbacteria:AAC67755 intact:EBI-9232288|uniprotkb:Q5VTD7|uniprotkb:Q9UD88|ensembl:ENSP00000321334|ensembl:ENSP00000395608 psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name) psi-mi:apoa_human(display_long)|uniprotkb:LPA(gene name)|psi-mi:LPA(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302598|imex:IM-27647-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67755(transcript)|ensemblbacteria:CT_164(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84166|refseq:NP_219667.1|refseq:WP_010725105.1 ensembl:ENSG00000198670(gene)|ensembl:ENST00000316300(transcript)|ensembl:ENST00000447678(transcript)|go:"GO:0001968"(fibronectin binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006869"(lipid transport)|go:"GO:0008015"(blood circulation)|go:"GO:0008201"(heparin binding)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034358"(plasma lipoprotein particle)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P08519|rcsb pdb:1I71|rcsb pdb:1JFN|rcsb pdb:1KIV|rcsb pdb:2FEB|rcsb pdb:3KIV|rcsb pdb:4BV5|rcsb pdb:4BV7|rcsb pdb:4BVC|rcsb pdb:4BVD|rcsb pdb:4BVV|rcsb pdb:4BVW|rcsb pdb:4KIV|rcsb pdb:6RX7|reactome:R-HSA-8964041 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561 rogid:D9jx5U3Ke3Kq7u4mLcqtfBVysY09606 rigid:pYiXtRE8pFAP+nXrs41YP6kmJ6o false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84198 uniprotkb:Q9Y5J9 intact:EBI-22302615|ensemblbacteria:AAC67787 intact:EBI-1049085|uniprotkb:Q3KQS9|uniprotkb:Q9UN04|uniprotkb:B0YJA5|ensembl:ENSP00000422122 psi-mi:o84198_chltr(display_long)|uniprotkb:CT_195(locus name) psi-mi:tim8b_human(display_long)|uniprotkb:Deafness dystonia protein 2(gene name synonym)|uniprotkb:DDP-like protein(gene name synonym)|uniprotkb:TIM8B(gene name synonym)|uniprotkb:TIMM8B(gene name)|psi-mi:TIMM8B(display_short)|uniprotkb:DDP2(gene name synonym)|uniprotkb:DDPL(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302622|imex:IM-27647-85 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67787(transcript)|ensemblbacteria:CT_195(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84198|refseq:NP_219699.1|refseq:WP_010725118.1 refseq:NP_036591.2|ensembl:ENSG00000150779(gene)|ensembl:ENST00000504148(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0140318"(protein transporter activity)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:Q9Y5J9|reactome:R-HSA-1268020 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:j0Kp4k//hsLl+Z1Er9tJyOPMeTM272561 rogid:7DK/1BIkwyl9KMIgEFWqRhZn2ZE9606 rigid:lATlSScRobTKDWyAYNIAoUfyM5k false strep tag:c-c|binding-associated region:212-363 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84198 uniprotkb:O60220 intact:EBI-22302615|ensemblbacteria:AAC67787 intact:EBI-1049822|uniprotkb:Q6IRW6|uniprotkb:B2R5A6|ensembl:ENSP00000361993 psi-mi:o84198_chltr(display_long)|uniprotkb:CT_195(locus name) psi-mi:tim8a_human(display_long)|uniprotkb:Deafness dystonia protein 1(gene name synonym)|uniprotkb:X-linked deafness dystonia protein(gene name synonym)|uniprotkb:TIMM8A(gene name)|psi-mi:TIMM8A(display_short)|uniprotkb:DDP(gene name synonym)|uniprotkb:DDP1(gene name synonym)|uniprotkb:TIM8A(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302622|imex:IM-27647-85 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67787(transcript)|ensemblbacteria:CT_195(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84198|refseq:NP_219699.1|refseq:WP_010725118.1 refseq:NP_004076.1|reactome:R-HSA-1268020|ensembl:ENSG00000126953(gene)|ensembl:ENST00000372902(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007399"(nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:O60220 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:j0Kp4k//hsLl+Z1Er9tJyOPMeTM272561 rogid:v01DxxXFU24eNjL3zVBvqQP9zA49606 rigid:lATlSScRobTKDWyAYNIAoUfyM5k false strep tag:c-c|binding-associated region:212-363 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84198 uniprotkb:P54727 intact:EBI-22302615|ensemblbacteria:AAC67787 intact:EBI-954531|uniprotkb:Q8WUB0|uniprotkb:B3KWK8|ensembl:ENSP00000350708|uniprotkb:G5E9P0|uniprotkb:Q7Z5K8 psi-mi:o84198_chltr(display_long)|uniprotkb:CT_195(locus name) psi-mi:rd23b_human(display_long)|uniprotkb:XP-C repair-complementing complex 58 kDa protein(gene name synonym)|uniprotkb:RAD23B(gene name)|psi-mi:RAD23B(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302622|imex:IM-27647-85 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67787(transcript)|ensemblbacteria:CT_195(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84198|refseq:NP_219699.1|refseq:WP_010725118.1 refseq:NP_002865.1|refseq:NP_001231653.1|ensembl:ENSG00000119318(gene)|ensembl:ENST00000358015(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR036353|interpro:IPR041811|mint:P54727|rcsb pdb:1P1A|rcsb pdb:1PVE|rcsb pdb:1UEL|reactome:R-HSA-532668|reactome:R-HSA-5689877|reactome:R-HSA-5696394|reactome:R-HSA-5696395|interpro:IPR029071|dip:DIP-39944N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:j0Kp4k//hsLl+Z1Er9tJyOPMeTM272561 rogid:msyh4+G2TzDW+xgGjixPKWWrjRE9606 rigid:lATlSScRobTKDWyAYNIAoUfyM5k false strep tag:c-c|binding-associated region:212-363 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84225 uniprotkb:Q8IWV7 intact:EBI-22302631|ensemblbacteria:AAC67814 intact:EBI-711736|uniprotkb:O60708|uniprotkb:O75492|uniprotkb:Q14D45|uniprotkb:Q68DN9|uniprotkb:Q8IWY6|uniprotkb:Q96JY4|ensembl:ENSP00000290650 psi-mi:o84225_chltr(display_long)|uniprotkb:CT_222(locus name) psi-mi:ubr1_human(display_long)|uniprotkb:N-recognin-1(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3-alpha-1(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3-alpha-I(gene name synonym)|uniprotkb:UBR1(gene name)|psi-mi:UBR1(display_short)|uniprotkb:RING-type E3 ubiquitin transferase UBR1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302636|imex:IM-27647-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67814(transcript)|ensemblbacteria:CT_222(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84225 refseq:NP_777576.1|dip:DIP-47033N|ensembl:ENSG00000159459(gene)|ensembl:ENST00000290650(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000502"(proteasome complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070728"(leucine binding)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR003769(Adaptor protein ClpS, core)|interpro:IPR014719(Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like)|interpro:IPR036390|interpro:IPR039164|interpro:IPR042065|interpro:IPR044046|mint:Q8IWV7|rcsb pdb:3NY1|rcsb pdb:5TDC|reactome:R-HSA-983168 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:/d4W43RkW9aL5Doe4hdOflMCD88272561 rogid:BcTsfaVfIa+WpIb8EPaPca2UZN89606 rigid:qCw4WbtSlzAQMXFLdo8slFFXqzc false strep tag:c-c|binding-associated region:89-129 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84225 uniprotkb:Q71F23 intact:EBI-22302631|ensemblbacteria:AAC67814 intact:EBI-2515234|uniprotkb:Q09GN2|ensembl:ENSP00000281453|uniprotkb:Q32Q71|uniprotkb:A2RRD9|uniprotkb:Q9H5G1 psi-mi:o84225_chltr(display_long)|uniprotkb:CT_222(locus name) psi-mi:cenpu_human(display_long)|uniprotkb:CENPU(gene name)|psi-mi:CENPU(display_short)|uniprotkb:Centromere protein of 50 kDa(gene name synonym)|uniprotkb:ICEN24(gene name synonym)|uniprotkb:Interphase centromere complex protein 24(gene name synonym)|uniprotkb:KLIP1(gene name synonym)|uniprotkb:KSHV latent nuclear antigen-interacting protein 1(gene name synonym)|uniprotkb:MLF1-interacting protein(gene name synonym)|uniprotkb:MLF1IP(gene name synonym)|uniprotkb:PBIP1(gene name synonym)|uniprotkb:Polo-box-interacting protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302636|imex:IM-27647-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67814(transcript)|ensemblbacteria:CT_222(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84225 ensembl:ENSG00000151725(gene)|ensembl:ENST00000281453(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043009"(chordate embryonic development)|interpro:IPR025214|mint:Q71F23|reactome:R-HSA-141444|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-2467813|refseq:NP_078905.2|dip:DIP-48539N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:/d4W43RkW9aL5Doe4hdOflMCD88272561 rogid:9FtaN8LMgqRrTXtmbt5NDbKCyus9606 rigid:qCw4WbtSlzAQMXFLdo8slFFXqzc false strep tag:c-c|binding-associated region:89-129 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84225 uniprotkb:Q8IWV8 intact:EBI-22302631|ensemblbacteria:AAC67814 intact:EBI-1237260|uniprotkb:O15057|uniprotkb:Q4VXK2|uniprotkb:Q5TFH6|uniprotkb:Q6P2I2|uniprotkb:Q6ZUD0|ensembl:ENSP00000361990 psi-mi:o84225_chltr(display_long)|uniprotkb:CT_222(locus name) psi-mi:ubr2_human(display_long)|uniprotkb:UBR2(gene name)|psi-mi:UBR2(display_short)|uniprotkb:C6orf133(gene name synonym)|uniprotkb:KIAA0349(gene name synonym)|uniprotkb:N-recognin-2(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3-alpha-2(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3-alpha-II(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR2(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302636|imex:IM-27647-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67814(transcript)|ensemblbacteria:CT_222(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84225 refseq:NP_001171730.1|refseq:NP_056070.1|refseq:XP_005249022.1|dip:DIP-38165N|ensembl:ENSG00000024048(gene)|ensembl:ENST00000372899(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070728"(leucine binding)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR003769(Adaptor protein ClpS, core)|interpro:IPR014719(Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like)|interpro:IPR036390|interpro:IPR039164|interpro:IPR042065|interpro:IPR044046|mint:Q8IWV8|rcsb pdb:3NY2|rcsb pdb:3NY3|rcsb pdb:5TDA|rcsb pdb:5TDB|rcsb pdb:5TDD|rcsb pdb:5UM3|reactome:R-HSA-983168 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:/d4W43RkW9aL5Doe4hdOflMCD88272561 rogid:FhRNI+FmJXWFjMAY1EUCiwqZPGY9606 rigid:qCw4WbtSlzAQMXFLdo8slFFXqzc false strep tag:c-c|binding-associated region:89-129 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84226 uniprotkb:Q14677 intact:EBI-22302645|ensemblbacteria:AAC67815 intact:EBI-1171113|uniprotkb:Q8NAF1|uniprotkb:Q96E05|uniprotkb:D3DQJ6|uniprotkb:B7Z6F8|intact:EBI-28971708|ensembl:ENSP00000388340 psi-mi:o84226_chltr(display_long)|uniprotkb:CT_223(locus name) psi-mi:epn4_human(display_long)|uniprotkb:CLINT1(gene name)|psi-mi:CLINT1(display_short)|uniprotkb:ENTH(gene name synonym)|uniprotkb:EPN4(gene name synonym)|uniprotkb:EPNR(gene name synonym)|uniprotkb:KIAA0171(gene name synonym)|uniprotkb:Epsin-4(gene name synonym)|uniprotkb:Epsin-related protein(gene name synonym)|uniprotkb:Enthoprotin(gene name synonym)|uniprotkb:Clathrin-interacting protein localized in the trans-Golgi region(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302652|imex:IM-27647-87 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67815(transcript)|ensemblbacteria:CT_223(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84226|refseq:NP_219728.1|refseq:WP_010725128.1 ensembl:ENSP00000388340|ensembl:ENST00000523094|ensembl:ENSP00000429345|ensembl:ENST00000523908|ensembl:ENSP00000429824|ensembl:ENST00000530742|ensembl:ENSP00000433419|refseq:NP_001182484.1|refseq:NP_001182485.1|refseq:NP_055481.1|ensembl:ENSG00000113282(gene)|ensembl:ENST00000411809(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030544|mint:Q14677|rcsb pdb:1XGW|rcsb pdb:2QY7|rcsb pdb:2V8S|reactome:R-HSA-432722|dip:DIP-45604N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:cwfEeY7cDtx5J6pOS7Zz2bvqypM272561 rogid:cflzNAWnEQR6zTr4d+hwfy1doC49606 rigid:L/xuBJ88nYHdu/gTJoKSSLmQh7M false strep tag:c-c|binding-associated region:84-270 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84226 uniprotkb:Q9Y678 intact:EBI-22302645|ensemblbacteria:AAC67815 intact:EBI-1049127|uniprotkb:A8K6M8|uniprotkb:B3KMF6|uniprotkb:Q54AC4|ensembl:ENSP00000325002 psi-mi:o84226_chltr(display_long)|uniprotkb:CT_223(locus name) psi-mi:copg1_human(display_long)|uniprotkb:COPG1(gene name)|psi-mi:COPG1(display_short)|uniprotkb:COPG(gene name synonym)|uniprotkb:Gamma-1-coat protein(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302652|imex:IM-27647-87 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67815(transcript)|ensemblbacteria:CT_223(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84226|refseq:NP_219728.1|refseq:WP_010725128.1 refseq:NP_057212.1|ensembl:ENSG00000181789(gene)|ensembl:ENST00000314797(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9Y678|rcsb pdb:1R4X|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-29872N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:cwfEeY7cDtx5J6pOS7Zz2bvqypM272561 rogid:P3wujl1rJH+o0vUUl/rLp0PEpMU9606 rigid:L/xuBJ88nYHdu/gTJoKSSLmQh7M false strep tag:c-c|binding-associated region:84-270 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84226 uniprotkb:Q9P2E9 intact:EBI-22302645|ensemblbacteria:AAC67815 intact:EBI-2371806|uniprotkb:A2A2S6|uniprotkb:A6NCN6|uniprotkb:O75300|uniprotkb:O75301|uniprotkb:Q5W165|uniprotkb:Q96SB2|uniprotkb:Q9BWP1|uniprotkb:Q9H476|uniprotkb:A0A0A0MRV0|intact:EBI-28985482|ensembl:ENSP00000246043|ensembl:ENSP00000367044 psi-mi:o84226_chltr(display_long)|uniprotkb:CT_223(locus name) psi-mi:rrbp1_human(display_long)|uniprotkb:RRBP1(gene name)|psi-mi:RRBP1(display_short)|uniprotkb:KIAA1398(gene name synonym)|uniprotkb:Ribosome receptor protein(gene name synonym)|uniprotkb:180 kDa ribosome receptor homolog(gene name synonym)|uniprotkb:ES/130-related protein(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302652|imex:IM-27647-87 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67815(transcript)|ensemblbacteria:CT_223(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84226|refseq:NP_219728.1|refseq:WP_010725128.1 refseq:NP_001036041.1|refseq:NP_004578.2|ensembl:ENSP00000246043|ensembl:ENST00000360807|ensembl:ENSP00000354045|ensembl:ENST00000377807|ensembl:ENSP00000367038|ensembl:ENSP00000367044|ensembl:ENSG00000125844(gene)|ensembl:ENST00000246043(transcript)|ensembl:ENST00000377813(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR007794(Ribosome receptor lysine or proline rich)|interpro:IPR040248|mint:Q9P2E9 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:cwfEeY7cDtx5J6pOS7Zz2bvqypM272561 rogid:uOiVzIAM5bsSl2s1BSIfnUtZ3Ms9606 rigid:L/xuBJ88nYHdu/gTJoKSSLmQh7M false strep tag:c-c|binding-associated region:84-270 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3G5 uniprotkb:A8MVJ9 intact:EBI-357542|uniprotkb:Q6UX20|uniprotkb:Q8NBL7|uniprotkb:Q96AR7|uniprotkb:Q9HB41|ensembl:ENSP00000265394|ensembl:ENSP00000379572|ensembl:ENSP00000387164|intact:EBI-1058665|uniprotkb:A4D1A4 intact:EBI-6152775 psi-mi:cpvl_human(display_long)|uniprotkb:CPVL(gene name)|psi-mi:CPVL(display_short)|uniprotkb:VLP(gene name synonym)|uniprotkb:UNQ197/PRO223(orf name)|uniprotkb:PSEC0124(orf name)|uniprotkb:Carboxypeptidase, vitellogenic-like(gene name synonym)|uniprotkb:Vitellogenic carboxypeptidase-like protein(gene name synonym) psi-mi:hpf1l_human(display_long) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302669|imex:IM-27647-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000106066(gene)|ensembl:ENST00000265394(transcript)|ensembl:ENST00000396276(transcript)|ensembl:ENST00000409850(transcript)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|mint:Q9H3G5|refseq:NP_061902.2|refseq:NP_112601.3|refseq:XP_011513739.1|refseq:NP_001334981.1|refseq:NP_001334983.1 mint:A8MVJ9|interpro:IPR019361|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0042393"(histone binding)|go:"GO:0072572"(poly-ADP-D-ribose binding) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:antgab61u6D+KmbopQeowXqSqWQ9606 rogid:5l1U+uPhO4bJjJY0H9YQC8YWrRs9606 rigid:6AguGKRRy/plXnvk1OZ1fsKQJZ4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3G5 uniprotkb:O84227 intact:EBI-357542|uniprotkb:Q6UX20|uniprotkb:Q8NBL7|uniprotkb:Q96AR7|uniprotkb:Q9HB41|ensembl:ENSP00000265394|ensembl:ENSP00000379572|ensembl:ENSP00000387164|intact:EBI-1058665|uniprotkb:A4D1A4 intact:EBI-22302662|ensemblbacteria:AAC67816 psi-mi:cpvl_human(display_long)|uniprotkb:CPVL(gene name)|psi-mi:CPVL(display_short)|uniprotkb:VLP(gene name synonym)|uniprotkb:UNQ197/PRO223(orf name)|uniprotkb:PSEC0124(orf name)|uniprotkb:Carboxypeptidase, vitellogenic-like(gene name synonym)|uniprotkb:Vitellogenic carboxypeptidase-like protein(gene name synonym) psi-mi:o84227_chltr(display_long)|uniprotkb:CT_224(locus name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:272561(chltr)|taxid:272561(chltr) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302669|imex:IM-27647-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000106066(gene)|ensembl:ENST00000265394(transcript)|ensembl:ENST00000396276(transcript)|ensembl:ENST00000409850(transcript)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|mint:Q9H3G5|refseq:NP_061902.2|refseq:NP_112601.3|refseq:XP_011513739.1|refseq:NP_001334981.1|refseq:NP_001334983.1 ensemblbacteria:AAC67816(transcript)|ensemblbacteria:CT_224(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84227|refseq:NP_219729.1|refseq:WP_009873078.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:antgab61u6D+KmbopQeowXqSqWQ9606 rogid:p1+tQrS/4/mC6+KIi6kLelc2MAo272561 rigid:6AguGKRRy/plXnvk1OZ1fsKQJZ4 false - binding-associated region:84-147|strep tag:c-c - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3G5 uniprotkb:O95153 intact:EBI-357542|uniprotkb:Q6UX20|uniprotkb:Q8NBL7|uniprotkb:Q96AR7|uniprotkb:Q9HB41|ensembl:ENSP00000265394|ensembl:ENSP00000379572|ensembl:ENSP00000387164|intact:EBI-1058665|uniprotkb:A4D1A4 intact:EBI-5915931|uniprotkb:O75111|uniprotkb:Q8N5W3|ensembl:ENSP00000345824|intact:EBI-28971165 psi-mi:cpvl_human(display_long)|uniprotkb:CPVL(gene name)|psi-mi:CPVL(display_short)|uniprotkb:VLP(gene name synonym)|uniprotkb:UNQ197/PRO223(orf name)|uniprotkb:PSEC0124(orf name)|uniprotkb:Carboxypeptidase, vitellogenic-like(gene name synonym)|uniprotkb:Vitellogenic carboxypeptidase-like protein(gene name synonym) psi-mi:rimb1_human(display_long)|uniprotkb:TSPOAP1(gene name)|psi-mi:TSPOAP1(display_short)|uniprotkb:BZRAP1(gene name synonym)|uniprotkb:KIAA0612(gene name synonym)|uniprotkb:Peripheral benzodiazepine receptor-interacting protein(gene name synonym)|uniprotkb:RBP1(gene name synonym)|uniprotkb:RIMBP1(gene name synonym)|uniprotkb:RIMS-binding protein 1(gene name synonym)|uniprotkb:TSPO-associated protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302669|imex:IM-27647-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000106066(gene)|ensembl:ENST00000265394(transcript)|ensembl:ENST00000396276(transcript)|ensembl:ENST00000409850(transcript)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|mint:Q9H3G5|refseq:NP_061902.2|refseq:NP_112601.3|refseq:XP_011513739.1|refseq:NP_001334981.1|refseq:NP_001334983.1 ensembl:ENST00000268893|ensembl:ENSP00000268893|ensembl:ENSP00000345824|refseq:XP_006722236.1|refseq:NP_001248764.1|refseq:NP_004749.2|refseq:NP_077729.1|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|mint:O95153|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-196108|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0030156"(benzodiazepine receptor binding)|go:"GO:0044305"(calyx of Held)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099626"(voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels)|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000005379(gene)|ensembl:ENST00000343736(transcript)|go:"GO:0005737"(cytoplasm) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:antgab61u6D+KmbopQeowXqSqWQ9606 rogid:nOwDlLr5DTjN2tJNR3h0zxrU1Z49606 rigid:6AguGKRRy/plXnvk1OZ1fsKQJZ4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3G5 uniprotkb:Q6Q0C0 intact:EBI-357542|uniprotkb:Q6UX20|uniprotkb:Q8NBL7|uniprotkb:Q96AR7|uniprotkb:Q9HB41|ensembl:ENSP00000265394|ensembl:ENSP00000379572|ensembl:ENSP00000387164|intact:EBI-1058665|uniprotkb:A4D1A4 intact:EBI-307556|uniprotkb:Q9H073|ensembl:ENSP00000318944 psi-mi:cpvl_human(display_long)|uniprotkb:CPVL(gene name)|psi-mi:CPVL(display_short)|uniprotkb:VLP(gene name synonym)|uniprotkb:UNQ197/PRO223(orf name)|uniprotkb:PSEC0124(orf name)|uniprotkb:Carboxypeptidase, vitellogenic-like(gene name synonym)|uniprotkb:Vitellogenic carboxypeptidase-like protein(gene name synonym) psi-mi:traf7_human(display_long)|uniprotkb:TRAF7(gene name)|psi-mi:TRAF7(display_short)|uniprotkb:TNF receptor-associated factor 7(gene name synonym)|uniprotkb:RING finger and WD repeat-containing protein 1(gene name synonym)|uniprotkb:RING finger protein 119(gene name synonym)|uniprotkb:RFWD1(gene name synonym)|uniprotkb:RNF119(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF7(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302669|imex:IM-27647-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000106066(gene)|ensembl:ENST00000265394(transcript)|ensembl:ENST00000396276(transcript)|ensembl:ENST00000409850(transcript)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|mint:Q9H3G5|refseq:NP_061902.2|refseq:NP_112601.3|refseq:XP_011513739.1|refseq:NP_001334981.1|refseq:NP_001334983.1 refseq:NP_115647.2|ensembl:ENSG00000131653(gene)|ensembl:ENST00000326181(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017907|interpro:IPR019775|interpro:IPR020472|interpro:IPR027370|interpro:IPR036322|mint:Q6Q0C0|reactome:R-HSA-983168 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:antgab61u6D+KmbopQeowXqSqWQ9606 rogid:46dtsS1OairncB0fnINSW1aY2789606 rigid:6AguGKRRy/plXnvk1OZ1fsKQJZ4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84229 uniprotkb:Q9Y608 intact:EBI-22302680|ensemblbacteria:AAC67818 intact:EBI-1023718|uniprotkb:Q68CV3|uniprotkb:Q9NXH5|uniprotkb:A8K649|uniprotkb:A8MXR0|uniprotkb:B4DY63|ensembl:ENSP00000338727 psi-mi:o84229_chltr(display_long)|uniprotkb:CT_226(locus name) psi-mi:lrrf2_human(display_long)|uniprotkb:LRRFIP2(gene name)|psi-mi:LRRFIP2(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302687|imex:IM-27647-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67818(transcript)|ensemblbacteria:CT_226(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84229|refseq:NP_219731.1|refseq:WP_010725129.1 refseq:NP_001127841.1|refseq:NP_006300.1|refseq:NP_060194.1|refseq:XP_011532519.1|refseq:XP_011532520.1|refseq:XP_011532521.1|refseq:NP_001269620.1|ensembl:ENSG00000093167(gene)|ensembl:ENST00000336686(transcript)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030275"(LRR domain binding)|interpro:IPR019139|mint:Q9Y608|refseq:XP_005265596.1|refseq:XP_005265597.1|refseq:XP_016862973.1|refseq:NP_001335239.1|refseq:NP_001335240.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:H7GYv0eZQr/CnxlDvp7PBXZkd+k272561 rogid:ma/crL7UY91uJ8bqLfkX3K8aQLI9606 rigid:WBtuxKE8hconGkNe4fVANgNpYxQ false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84229 uniprotkb:Q9NYL9 intact:EBI-22302680|ensemblbacteria:AAC67818 intact:EBI-352614|ensembl:ENSP00000308753|uniprotkb:Q9NT43|uniprotkb:Q9NZR0|uniprotkb:B2R6G7 psi-mi:o84229_chltr(display_long)|uniprotkb:CT_226(locus name) psi-mi:tmod3_human(display_long)|uniprotkb:TMOD3(gene name)|psi-mi:TMOD3(display_short)|uniprotkb:Ubiquitous tropomodulin(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302687|imex:IM-27647-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67818(transcript)|ensemblbacteria:CT_226(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84229|refseq:NP_219731.1|refseq:WP_010725129.1 ensembl:ENSG00000138594(gene)|ensembl:ENST00000308580(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005912"(adherens junction)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0030016"(myofibril)|go:"GO:0030239"(myofibril assembly)|refseq:NP_055362.1|go:"GO:0048821"(erythrocyte development)|go:"GO:0051694"(pointed-end actin filament capping)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1901992"(positive regulation of mitotic cell cycle phase transition)|interpro:IPR004934(Tropomodulin)|interpro:IPR030133|interpro:IPR032675|mint:Q9NYL9|reactome:R-HSA-390522|reactome:R-HSA-9013418|reactome:R-HSA-9696264|refseq:XP_016877576.1|refseq:XP_016877577.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:H7GYv0eZQr/CnxlDvp7PBXZkd+k272561 rogid:crEfCAAepSPAE8ByBpD4Sr14P5I9606 rigid:WBtuxKE8hconGkNe4fVANgNpYxQ false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84229 uniprotkb:Q32MZ4 intact:EBI-22302680|ensemblbacteria:AAC67818 intact:EBI-1369100|uniprotkb:O75766|uniprotkb:O75799|uniprotkb:Q32MZ5|uniprotkb:Q53T49|uniprotkb:Q6PKG2|uniprotkb:E9PGZ2|uniprotkb:Q9Y607|intact:EBI-28987401|ensembl:ENSP00000375857 psi-mi:o84229_chltr(display_long)|uniprotkb:CT_226(locus name) psi-mi:lrrf1_human(display_long)|uniprotkb:LRRFIP1(gene name)|psi-mi:LRRFIP1(display_short)|uniprotkb:GCF2(gene name synonym)|uniprotkb:TRIP(gene name synonym)|uniprotkb:TAR RNA-interacting protein(gene name synonym)|uniprotkb:GC-binding factor 2(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302687|imex:IM-27647-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67818(transcript)|ensemblbacteria:CT_226(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84229|refseq:NP_219731.1|refseq:WP_010725129.1 refseq:NP_001131024.1|refseq:NP_001131025.1|refseq:NP_004726.2|ensembl:ENST00000244815|ensembl:ENSP00000244815|ensembl:ENST00000289175|ensembl:ENSP00000289175|ensembl:ENST00000308482|ensembl:ENSP00000310109|ensembl:ENSP00000375857|refseq:NP_001131022.1|ensembl:ENSG00000124831(gene)|ensembl:ENST00000392000(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR019139|mint:Q32MZ4|rcsb pdb:4H22|reactome:R-HSA-1839117|reactome:R-HSA-3134973|reactome:R-HSA-5655302 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:H7GYv0eZQr/CnxlDvp7PBXZkd+k272561 rogid:GRBGUu5k+BNhFDb4Z2B2XkQ0mcQ9606 rigid:WBtuxKE8hconGkNe4fVANgNpYxQ false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84229 uniprotkb:Q13045 intact:EBI-22302680|ensemblbacteria:AAC67818 intact:EBI-351549|ensembl:ENSP00000491480|ensembl:ENSP00000324573|uniprotkb:B4DIL0|uniprotkb:F5H407|uniprotkb:J3QLG3 psi-mi:o84229_chltr(display_long)|uniprotkb:CT_226(locus name) psi-mi:flii_human(display_long)|uniprotkb:FLII(gene name)|psi-mi:FLII(display_short)|uniprotkb:FLIL(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302687|imex:IM-27647-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67818(transcript)|ensemblbacteria:CT_226(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84229|refseq:NP_219731.1|refseq:WP_010725129.1 refseq:NP_002009.1|refseq:NP_001243193.1|ensembl:ENST00000327031(transcript)|ensembl:ENST00000638207(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030239"(myofibril assembly)|go:"GO:0034451"(centriolar satellite)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR029919|interpro:IPR032675|mint:Q13045|ensembl:ENSG00000177731(gene)|ensembl:ENSG00000284571(gene)|refseq:NP_001243194.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:H7GYv0eZQr/CnxlDvp7PBXZkd+k272561 rogid:hzls0Ir+lr0+wNsTUeIURV3fXVQ9606 rigid:WBtuxKE8hconGkNe4fVANgNpYxQ false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVW2 uniprotkb:O84230 intact:EBI-1996544|uniprotkb:Q9Y598|uniprotkb:Q96D38|uniprotkb:D3DTE0|uniprotkb:B2RBQ1|ensembl:ENSP00000253571|ensembl:ENSP00000328059 intact:EBI-22302695|ensemblbacteria:AAC67819 psi-mi:rnf12_human(display_long)|uniprotkb:RLIM(gene name)|psi-mi:RLIM(display_short)|uniprotkb:RNF12(gene name synonym)|uniprotkb:RING finger protein 12(gene name synonym)|uniprotkb:LIM domain-interacting RING finger protein(gene name synonym)|uniprotkb:RING finger LIM domain-binding protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-43(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RLIM(gene name synonym) psi-mi:o84230_chltr(display_long)|uniprotkb:CT_227(locus name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:272561(chltr)|taxid:272561(chltr) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302702|imex:IM-27647-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057204.2|refseq:NP_899196.1|ensembl:ENSG00000131263(gene)|ensembl:ENST00000332687(transcript)|ensembl:ENST00000349225(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060816"(random inactivation of X chromosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900095"(regulation of dosage compensation by inactivation of X chromosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9NVW2|rcsb pdb:6W7Z|rcsb pdb:6W9A|rcsb pdb:6W9D|reactome:R-HSA-983168 ensemblbacteria:CT_227(gene)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAC67819(transcript)|mint:O84230|refseq:NP_219732.1|refseq:WP_009871574.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:jEHiOt7hjZc5HU6E/XQGE7zdZbw9606 rogid:zp/rtaPMi1WqXCfsRhEh33c+1b4272561 rigid:jfl/UL+8rniRM80iuTBkx6BxC1k false - binding-associated region:87-132|strep tag:c-c - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14974 uniprotkb:O84231 intact:EBI-351726|uniprotkb:Q2NKL4|uniprotkb:Q569H0|uniprotkb:Q86WU3|uniprotkb:Q8NFR6|uniprotkb:Q9BYH0|intact:EBI-28988491|uniprotkb:B4DZ09|uniprotkb:F8VWB4|ensembl:ENSP00000261207|ensembl:ENSP00000389168 intact:EBI-22302709|ensemblbacteria:AAC67820 psi-mi:mypt1_human(display_long)|uniprotkb:PPP1R12A(gene name)|psi-mi:PPP1R12A(display_short)|uniprotkb:MBS(gene name synonym)|uniprotkb:MYPT1(gene name synonym)|uniprotkb:Myosin phosphatase-targeting subunit 1(gene name synonym)|uniprotkb:Protein phosphatase myosin-binding subunit(gene name synonym) psi-mi:o84231_chltr(display_long)|uniprotkb:CT_228(locus name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:272561(chltr)|taxid:272561(chltr) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302716|imex:IM-27647-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137357.1|refseq:NP_001137358.1|refseq:NP_002471.1|refseq:NP_001231919.1|refseq:NP_001231921.1|refseq:XP_011536685.1|ensembl:ENSP00000261207|ensembl:ENST00000437004|ensembl:ENSP00000416769|ensembl:ENSP00000389168|ensembl:ENSP00000449514|ensembl:ENST00000550107|ensembl:ENSP00000446855|ensembl:ENST00000546369|dip:DIP-33186N|ensembl:ENSG00000058272(gene)|ensembl:ENST00000261207(transcript)|ensembl:ENST00000450142(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031672"(A band)|go:"GO:0035507"(regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035508"(positive regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035690"|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043292"(contractile fiber)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR002110(Ankyrin)|interpro:IPR017401(Protein phosphatase 1, regulatory subunits 12A/B/C, eukaryote)|interpro:IPR020683|interpro:IPR031775|interpro:IPR036770|mint:O14974|rcsb pdb:2KJY|rcsb pdb:5HUZ|reactome:R-HSA-2565942|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123 ensemblbacteria:AAC67820(transcript)|ensemblbacteria:CT_228(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84231|refseq:NP_219733.1|refseq:WP_009873080.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:Xi5lGskc0tWQCHtbYlgR45ERMSk9606 rogid:DZj7bSZEXikp0OeSEhXdXMzjssU272561 rigid:oB0ZMsHXnaEyt4jlGsCLxcRU0t8 false - strep tag:c-c - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84231 uniprotkb:P35221 intact:EBI-22302709|ensemblbacteria:AAC67820 intact:EBI-701918|uniprotkb:Q12795|intact:EBI-7950809|intact:MINT-4924748|uniprotkb:Q8N1C0|ensembl:ENSP00000304669 psi-mi:o84231_chltr(display_long)|uniprotkb:CT_228(locus name) psi-mi:ctna1_human(display_long)|uniprotkb:Cadherin-associated protein(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-13(gene name synonym)|uniprotkb:CTNNA1(gene name)|psi-mi:CTNNA1(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302722|imex:IM-27647-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67820(transcript)|ensemblbacteria:CT_228(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84231|refseq:NP_219733.1|refseq:WP_009873080.1 refseq:NP_001894.2|refseq:NP_001277236.1|refseq:NP_001277238.1|refseq:NP_001277239.1|refseq:NP_001277241.1|refseq:NP_001310911.1|refseq:NP_001310912.1|refseq:NP_001310913.1|refseq:NP_001310916.1|refseq:NP_001310917.1|refseq:NP_001310918.1|refseq:NP_001310919.1|refseq:NP_001310920.1|refseq:NP_001310921.1|refseq:NP_001310922.1|refseq:NP_001310923.1|refseq:NP_001310924.1|refseq:NP_001310925.1|refseq:NP_001310926.1|refseq:NP_001310927.1|refseq:NP_001310928.1|refseq:NP_001310929.1|dip:DIP-515N|ensembl:ENSG00000044115(gene)|ensembl:ENST00000302763(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P35221|rcsb pdb:1H6G|rcsb pdb:4EHP|rcsb pdb:4IGG|rcsb pdb:6UPV|rcsb pdb:6V2O|rcsb pdb:6V2P|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5626467 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:DZj7bSZEXikp0OeSEhXdXMzjssU272561 rogid:N5rM8wI4ep+iZcnXU2g5wlJmJao9606 rigid:EwCpvedmmc3knXWASh5vKEgnRyE false strep tag:c-c|binding-associated region:88-196 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84231 uniprotkb:Q53HC5 intact:EBI-22302709|ensemblbacteria:AAC67820 intact:EBI-724915|uniprotkb:Q8TAP0|uniprotkb:Q9NUX3|ensembl:ENSP00000300976 psi-mi:o84231_chltr(display_long)|uniprotkb:CT_228(locus name) psi-mi:klh26_human(display_long)|uniprotkb:KLHL26(gene name)|psi-mi:KLHL26(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302722|imex:IM-27647-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67820(transcript)|ensemblbacteria:CT_228(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84231|refseq:NP_219733.1|refseq:WP_009873080.1 refseq:NP_060786.1|ensembl:ENSG00000167487(gene)|ensembl:ENST00000300976(transcript)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030588|mint:Q53HC5 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:DZj7bSZEXikp0OeSEhXdXMzjssU272561 rogid:ttSomgoE7proVj7jmp9Umc/IbXk9606 rigid:EwCpvedmmc3knXWASh5vKEgnRyE false strep tag:c-c|binding-associated region:88-196 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84232 uniprotkb:Q9UNQ2 intact:EBI-22302746|ensemblbacteria:AAC67821 intact:EBI-395738|uniprotkb:O76025|uniprotkb:Q9BU77|uniprotkb:Q9UES1|ensembl:ENSP00000199320 psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name) psi-mi:dim1_human(display_long)|uniprotkb:DIMT1L(gene name synonym)|uniprotkb:DIM1 dimethyladenosine transferase 1 homolog(gene name synonym)|uniprotkb:DIM1 dimethyladenosine transferase 1-like(gene name synonym)|uniprotkb:HUSSY-05(orf name)|uniprotkb:"Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase"(gene name synonym)|uniprotkb:Probable 18S rRNA dimethylase(gene name synonym)|uniprotkb:DIMT1(gene name)|psi-mi:DIMT1(display_short)|uniprotkb:"Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase"(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302731|imex:IM-27647-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67821(transcript)|ensemblbacteria:CT_229(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84232|refseq:NP_219734.1|refseq:WP_010725130.1 refseq:NP_055288.1|ensembl:ENSG00000086189(gene)|ensembl:ENST00000199320(transcript)|go:"GO:0000179"("rRNA (adenine-N6,N6-)-dimethyltransferase activity")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0031167"(rRNA methylation)|go:"GO:0052909"("18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity")|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR001737(Ribosomal RNA adenine methylase transferase)|interpro:IPR011530(rRNA adenine dimethylase)|interpro:IPR020596|interpro:IPR020598|interpro:IPR029063|mint:Q9UNQ2|rcsb pdb:1ZQ9|rcsb pdb:6W6C|rcsb pdb:6W6F|reactome:R-HSA-6790901|refseq:NP_001335005.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561 rogid:hx0FRrx+XTeoziOqfesiw4KL+wo9606 rigid:8Q/SbwNlUZN9yoJsTbqUdb88ndw false strep tag:c-c|binding-associated region:93-215 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84232 uniprotkb:Q9H9L3 intact:EBI-22302746|ensemblbacteria:AAC67821 intact:EBI-751335|uniprotkb:Q64KA2|uniprotkb:D3DVC6|ensembl:ENSP00000323424|ensembl:ENSP00000357202 psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name) psi-mi:i20l2_human(display_long)|uniprotkb:ISG20L2(gene name)|psi-mi:ISG20L2(display_short)|uniprotkb:HSD38(orf name)|uniprotkb:HSD-38(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302731|imex:IM-27647-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67821(transcript)|ensemblbacteria:CT_229(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84232|refseq:NP_219734.1|refseq:WP_010725130.1 refseq:NP_001290024.1|refseq:XP_005245573.1|refseq:XP_006711623.1|refseq:XP_006711624.1|reactome:R-HSA-6791226|interpro:IPR037433|mint:Q9H9L3|ensembl:ENSG00000143319(gene)|ensembl:ENST00000313146(transcript)|ensembl:ENST00000368219(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR034933|interpro:IPR036397 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561 rogid:i/TZBz8UuJIRm7WZZKjHYU75AS89606 rigid:8Q/SbwNlUZN9yoJsTbqUdb88ndw false strep tag:c-c|binding-associated region:93-215 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84232 uniprotkb:P52294 intact:EBI-22302746|ensemblbacteria:AAC67821 intact:EBI-358383|uniprotkb:Q9BQ56|uniprotkb:Q6IBQ9|intact:EBI-1058734|ensembl:ENSP00000343701|uniprotkb:D3DN93 psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name) psi-mi:ima5_human(display_long)|uniprotkb:KPNA1(gene name)|psi-mi:KPNA1(display_short)|uniprotkb:RCH2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-1(gene name synonym)|uniprotkb:SRP1-beta(gene name synonym)|uniprotkb:RAG cohort protein 2(gene name synonym)|uniprotkb:Nucleoprotein interactor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302731|imex:IM-27647-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67821(transcript)|ensemblbacteria:CT_229(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84232|refseq:NP_219734.1|refseq:WP_010725130.1 refseq:NP_002255.3|ensembl:ENSG00000114030(gene)|ensembl:ENST00000344337(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014841"(skeletal muscle satellite cell proliferation)|go:"GO:0014901"(satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0030425"(dendrite)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52294|rcsb pdb:2JDQ|rcsb pdb:3TJ3|rcsb pdb:4B18|rcsb pdb:6WX9|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-162592|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180910|reactome:R-HSA-909733|reactome:R-HSA-9636249|dip:DIP-29296N|refseq:XP_005247494.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561 rogid:eha8sOMYqe0OC6eXBA4eJLLsKFs9606 rigid:8Q/SbwNlUZN9yoJsTbqUdb88ndw false strep tag:c-c|binding-associated region:93-215 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84232 uniprotkb:Q9Y248 intact:EBI-22302746|ensemblbacteria:AAC67821 intact:EBI-747491|uniprotkb:Q6IAG9|uniprotkb:D3DUM5|ensembl:ENSP00000253462 psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name) psi-mi:psf2_human(display_long)|uniprotkb:GINS complex subunit 2(gene name synonym)|uniprotkb:GINS2(gene name)|psi-mi:GINS2(display_short)|uniprotkb:CGI-122(orf name)|uniprotkb:DC5(orf name)|uniprotkb:HSPC037(orf name)|uniprotkb:PSF2(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302731|imex:IM-27647-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67821(transcript)|ensemblbacteria:CT_229(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84232|refseq:NP_219734.1|refseq:WP_010725130.1 refseq:NP_057179.1|dip:DIP-29332N|ensembl:ENSG00000131153(gene)|ensembl:ENST00000253462(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|mint:Q9Y248|rcsb pdb:2E9X|rcsb pdb:2EHO|rcsb pdb:2Q9Q|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176974 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561 rogid:OKFZLWhkmZNQxqS2tKptq61jsxs9606 rigid:8Q/SbwNlUZN9yoJsTbqUdb88ndw false strep tag:c-c|binding-associated region:93-215 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84232 uniprotkb:Q9BRX5 intact:EBI-22302746|ensemblbacteria:AAC67821 intact:EBI-2857315|uniprotkb:B2RDP3|uniprotkb:Q9H870|uniprotkb:E9PB21|ensembl:ENSP00000318196 psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name) psi-mi:psf3_human(display_long)|uniprotkb:GINS3(gene name)|psi-mi:GINS3(display_short)|uniprotkb:PSF3(gene name synonym)|uniprotkb:GINS complex subunit 3(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302731|imex:IM-27647-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67821(transcript)|ensemblbacteria:CT_229(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84232|refseq:NP_219734.1|refseq:WP_010725130.1 refseq:NP_001119601.1|refseq:NP_001119602.1|refseq:NP_073607.2|dip:DIP-29333N|ensembl:ENSG00000181938(gene)|ensembl:ENST00000318129(transcript)|go:"GO:0000811"(GINS complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071162"(CMG complex)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR010492(GINS complex, Psf3 component)|interpro:IPR021151|interpro:IPR036224|interpro:IPR038437|mint:Q9BRX5|rcsb pdb:2E9X|rcsb pdb:2EHO|rcsb pdb:2Q9Q|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176974 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561 rogid:3anXwRLIwu/t1G1v+P1yzhh7QqA9606 rigid:8Q/SbwNlUZN9yoJsTbqUdb88ndw false strep tag:c-c|binding-associated region:93-215 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84232 uniprotkb:Q9BRT9 intact:EBI-22302746|ensemblbacteria:AAC67821 intact:EBI-747500|uniprotkb:Q8N648|uniprotkb:B2R8H5|uniprotkb:D3DSY0|ensembl:ENSP00000276533|ensembl:ENSP00000428754 psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name) psi-mi:sld5_human(display_long)|uniprotkb:SLD5(gene name synonym)|uniprotkb:GINS complex subunit 4(gene name synonym)|uniprotkb:GINS4(gene name)|psi-mi:GINS4(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302731|imex:IM-27647-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67821(transcript)|ensemblbacteria:CT_229(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84232|refseq:NP_219734.1|refseq:WP_010725130.1 refseq:NP_115712.1|refseq:XP_005273716.1|dip:DIP-29334N|ensembl:ENSG00000147536(gene)|ensembl:ENST00000276533(transcript)|ensembl:ENST00000518671(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0071162"(CMG complex)|interpro:IPR008591(GINS complex, Sld5 component)|interpro:IPR021151|interpro:IPR031633|interpro:IPR036224|interpro:IPR038749|mint:Q9BRT9|rcsb pdb:2E9X|rcsb pdb:2EHO|rcsb pdb:2Q9Q|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176974 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561 rogid:DL/sJVWAbcV57zkjNgnsQ5acRi09606 rigid:8Q/SbwNlUZN9yoJsTbqUdb88ndw false strep tag:c-c|binding-associated region:93-215 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84232 uniprotkb:O43819 intact:EBI-22302746|ensemblbacteria:AAC67821 intact:EBI-357012|uniprotkb:Q3T1B5|uniprotkb:Q9UK87|ensembl:ENSP00000252785|ensembl:ENSP00000379046|ensembl:ENSP00000444242|ensembl:ENSP00000444433 psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name) psi-mi:sco2_human(display_long)|uniprotkb:SCO2(gene name)|psi-mi:SCO2(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302731|imex:IM-27647-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67821(transcript)|ensemblbacteria:CT_229(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84232|refseq:NP_219734.1|refseq:WP_010725130.1 refseq:NP_001162580.1|refseq:NP_001162581.1|refseq:NP_001162582.1|refseq:NP_005129.2|dip:DIP-46088N|go:"GO:0003012"(muscle system process)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0014823"(response to activity)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030016"(myofibril)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR003782(Copper chaperone SCO1/SenC)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017276(Synthesis of cytochrome c oxidase, Sco1/Sco2)|interpro:IPR036249|mint:O43819|rcsb pdb:2RLI|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|ensembl:ENSG00000284194(gene)|ensembl:ENST00000252785(transcript)|ensembl:ENST00000395693(transcript)|ensembl:ENST00000535425(transcript)|ensembl:ENST00000543927(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001701"(in utero embryonic development) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561 rogid:RaD9DPaOnFKJvwNRUK9KQdptmqc9606 rigid:8Q/SbwNlUZN9yoJsTbqUdb88ndw false strep tag:c-c|binding-associated region:93-215 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84232 uniprotkb:Q14691 intact:EBI-22302746|ensemblbacteria:AAC67821 intact:EBI-9019496|ensembl:ENSP00000262460|uniprotkb:Q9NQI7|uniprotkb:Q9NQE2 psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name) psi-mi:psf1_human(display_long)|uniprotkb:GINS1(gene name)|psi-mi:GINS1(display_short)|uniprotkb:GINS complex subunit 1(gene name synonym)|uniprotkb:KIAA0186(gene name synonym)|uniprotkb:PSF1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302731|imex:IM-27647-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67821(transcript)|ensemblbacteria:CT_229(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84232|refseq:NP_219734.1|refseq:WP_010725130.1 ensembl:ENSG00000101003(gene)|ensembl:ENST00000262460(transcript)|go:"GO:0000811"(GINS complex)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0071162"(CMG complex)|interpro:IPR005339(GINS complex, Psf1 component)|interpro:IPR036224|mint:Q14691|rcsb pdb:2E9X|rcsb pdb:2EHO|rcsb pdb:2Q9Q|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176974|go:"GO:1902983"(DNA strand elongation involved in mitotic DNA replication)|refseq:NP_066545.3|dip:DIP-29331N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561 rogid:uUjKx4tV7oRDtXaL9zDlBBQDRjQ9606 rigid:8Q/SbwNlUZN9yoJsTbqUdb88ndw false strep tag:c-c|binding-associated region:93-215 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84232 uniprotkb:Q9H0U4 intact:EBI-22302746|ensemblbacteria:AAC67821 intact:EBI-1045214|ensembl:ENSP00000310226|uniprotkb:A8K7S1 psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name) psi-mi:rab1b_human(display_long)|uniprotkb:RAB1B(gene name)|psi-mi:RAB1B(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302753|imex:IM-27647-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67821(transcript)|ensemblbacteria:CT_229(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84232|refseq:NP_219734.1|refseq:WP_010725130.1 ensembl:ENSG00000174903(gene)|ensembl:ENST00000311481(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0019068"(virion assembly)|go:"GO:0030133"(transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_112243.1|go:"GO:0070062"(extracellular exosome)|go:"GO:1903020"(positive regulation of glycoprotein metabolic process)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q9H0U4|rcsb pdb:3JZA|rcsb pdb:3NKV|rcsb pdb:4HLQ|rcsb pdb:4I1O|rcsb pdb:5O74|rcsb pdb:5SZH|rcsb pdb:5SZK|rcsb pdb:6SKU|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-42462N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561 rogid:EI6DHq7xCboSkoqGY5NmVY4Iqf09606 rigid:5HMDEJrYjkYgve+IpHzkWTi0c/Q false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84232 uniprotkb:Q15286 intact:EBI-22302746|ensemblbacteria:AAC67821 intact:EBI-722275|uniprotkb:B4E390|uniprotkb:B2R6E0|ensembl:ENSP00000229340 psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name) psi-mi:rab35_human(display_long)|uniprotkb:Ras-related protein Rab-1C(gene name synonym)|uniprotkb:GTP-binding protein RAY(gene name synonym)|uniprotkb:RAB35(gene name)|psi-mi:RAB35(display_short)|uniprotkb:RAB1C(gene name synonym)|uniprotkb:RAY(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302753|imex:IM-27647-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67821(transcript)|ensemblbacteria:CT_229(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84232|refseq:NP_219734.1|refseq:WP_010725130.1 refseq:NP_001161078.1|refseq:NP_006852.1|ensembl:ENSG00000111737(gene)|ensembl:ENST00000229340(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0008104"(protein localization)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0031253"(cell projection membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042470"(melanosome)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041815|mint:Q15286|rcsb pdb:3TW8|rcsb pdb:6EKK|rcsb pdb:6IF2|rcsb pdb:6IF3|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561 rogid:95pH+DyDjv9FcxFeMmGYoJ0KyPo9606 rigid:5HMDEJrYjkYgve+IpHzkWTi0c/Q false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84232 uniprotkb:P62820 intact:EBI-22302746|ensemblbacteria:AAC67821 intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286|ensembl:ENSP00000497078 psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name) psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302753|imex:IM-27647-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67821(transcript)|ensemblbacteria:CT_229(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84232|refseq:NP_219734.1|refseq:WP_010725130.1 refseq:NP_004152.1|refseq:NP_056358.1|ensembl:ENSG00000138069(gene)|ensembl:ENST00000409784(transcript)|ensembl:ENST00000649427(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0012505"(endomembrane system)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016477"(cell migration)|go:"GO:0019068"(virion assembly)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032402"(melanosome transport)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042470"(melanosome)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045296"(cadherin binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:1903020"(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-1063N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561 rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606 rigid:5HMDEJrYjkYgve+IpHzkWTi0c/Q false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P36406 uniprotkb:O84326 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 intact:EBI-22302763|ensemblbacteria:AAC67917 psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:272561(chltr)|taxid:272561(chltr) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302770|imex:IM-27647-89 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW ensemblbacteria:AAC67917(transcript)|ensemblbacteria:CT_324(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84326|refseq:NP_219829.1|refseq:WP_009871671.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561 rigid:HC69XjuDBYPmgu7P+sJwwCqstcE false - binding-associated region:184-303|strep tag:c-c - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84326 uniprotkb:Q9UBW8 intact:EBI-22302763|ensemblbacteria:AAC67917 intact:EBI-712982|ensembl:ENSP00000229251|ensembl:ENSP00000438115|ensembl:ENSP00000438363|ensembl:ENSP00000441852|ensembl:ENSP00000446039|uniprotkb:Q9NVX3|uniprotkb:Q9UJW4|uniprotkb:A8K9A6 psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name) psi-mi:csn7a_human(display_long)|uniprotkb:JAB1-containing signalosome subunit 7a(gene name synonym)|uniprotkb:Dermal papilla-derived protein 10(gene name synonym)|uniprotkb:COPS7A(gene name)|psi-mi:COPS7A(display_short)|uniprotkb:CSN7A(gene name synonym)|uniprotkb:DERP10(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302779|imex:IM-27647-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67917(transcript)|ensemblbacteria:CT_324(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84326|refseq:NP_219829.1|refseq:WP_009871671.1 ensembl:ENSG00000111652(gene)|ensembl:ENST00000229251(transcript)|ensembl:ENST00000534877(transcript)|ensembl:ENST00000534947(transcript)|ensembl:ENST00000539735(transcript)|ensembl:ENST00000543155(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0010387"(COP9 signalosome assembly)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR037757|interpro:IPR041481|mint:Q9UBW8|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|refseq:NP_001157565.1|refseq:NP_001157566.1|refseq:NP_001157567.1|refseq:NP_057403.1|refseq:XP_005253751.1|dip:DIP-53412N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561 rogid:KT1zw5OuZthyscvNa/4lW1iJz2Q9606 rigid:yDID0/eyWtb3ezHp4X3gzaUExYY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84326 uniprotkb:Q92905 intact:EBI-22302763|ensemblbacteria:AAC67917 intact:EBI-594661|uniprotkb:O15386|uniprotkb:Q6AW95|uniprotkb:Q86WQ4|uniprotkb:Q9BQ17|ensembl:ENSP00000350512 psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name) psi-mi:csn5_human(display_long)|uniprotkb:Jun activation domain-binding protein 1(gene name synonym)|uniprotkb:COPS5(gene name)|psi-mi:COPS5(display_short)|uniprotkb:CSN5(gene name synonym)|uniprotkb:JAB1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302779|imex:IM-27647-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67917(transcript)|ensemblbacteria:CT_324(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84326|refseq:NP_219829.1|refseq:WP_009871671.1 refseq:NP_006828.2|dip:DIP-34546N|ensembl:ENSG00000121022(gene)|ensembl:ENST00000357849(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006412"(translation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1990182"(exosomal secretion)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|interpro:IPR040961|mint:Q92905|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4F7O|rcsb pdb:4WSN|rcsb pdb:5JOG|rcsb pdb:5JOH|rcsb pdb:5M5Q|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561 rogid:GMgH8dW3KWILX6Mr/+XrgAV3xY49606 rigid:yDID0/eyWtb3ezHp4X3gzaUExYY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84326 uniprotkb:P13489 intact:EBI-22302763|ensemblbacteria:AAC67917 intact:EBI-1237106|uniprotkb:Q8IZK8|uniprotkb:Q96FD7|uniprotkb:Q9BQ80|uniprotkb:Q9UDK6|ensembl:ENSP00000346402|ensembl:ENSP00000348515|ensembl:ENSP00000380729|ensembl:ENSP00000380738|ensembl:ENSP00000380739|ensembl:ENSP00000416589|ensembl:ENSP00000433999|ensembl:ENSP00000435594|ensembl:ENSP00000478664|ensembl:ENSP00000479004|ensembl:ENSP00000479966|ensembl:ENSP00000480036|ensembl:ENSP00000484572|ensembl:ENSP00000487753|ensembl:ENSP00000487940|ensembl:ENSP00000488734 psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name) psi-mi:rini_human(display_long)|uniprotkb:RNH1(gene name)|psi-mi:RNH1(display_short)|uniprotkb:PRI(gene name synonym)|uniprotkb:RNH(gene name synonym)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym)|uniprotkb:Placental ribonuclease inhibitor(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302779|imex:IM-27647-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67917(transcript)|ensemblbacteria:CT_324(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84326|refseq:NP_219829.1|refseq:WP_009871671.1 refseq:NP_002930.2|refseq:NP_976317.1|refseq:NP_976318.1|refseq:NP_976319.1|refseq:NP_976320.1|refseq:NP_976321.1|refseq:NP_976322.1|refseq:NP_976323.1|refseq:XP_011518557.1|refseq:XP_011518559.1|refseq:XP_011518560.1|refseq:XP_011518561.1|refseq:XP_011518562.1|refseq:XP_011518563.1|refseq:XP_011518564.1|refseq:XP_011518565.1|refseq:XP_016873595.1|ensembl:ENST00000619599(transcript)|ensembl:ENST00000621211(transcript)|ensembl:ENST00000632527(transcript)|ensembl:ENST00000632954(transcript)|ensembl:ENST00000633287(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR041302|mint:P13489|rcsb pdb:1A4Y|rcsb pdb:1Z7X|rcsb pdb:2BEX|rcsb pdb:2Q4G|ensembl:ENSG00000023191(gene)|ensembl:ENSG00000276230(gene)|ensembl:ENST00000354420(transcript)|ensembl:ENST00000356187(transcript)|ensembl:ENST00000397604(transcript)|ensembl:ENST00000397614(transcript)|ensembl:ENST00000397615(transcript)|ensembl:ENST00000438658(transcript)|ensembl:ENST00000533410(transcript)|ensembl:ENST00000534797(transcript)|ensembl:ENST00000612988(transcript)|ensembl:ENST00000617351(transcript)|ensembl:ENST00000618184(transcript) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561 rogid:1WMWoYulk8Aj8HYhDcqnauddUFk9606 rigid:yDID0/eyWtb3ezHp4X3gzaUExYY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84326 uniprotkb:Q9H3P7 intact:EBI-22302763|ensemblbacteria:AAC67917 intact:EBI-1791792|uniprotkb:Q5VTJ0|uniprotkb:Q6P9F1|uniprotkb:Q8IZC5|uniprotkb:Q8N4D6|uniprotkb:Q9H6U3|uniprotkb:B2RB29|ensembl:ENSP00000355777 psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name) psi-mi:gcp60_human(display_long)|uniprotkb:GOCAP1(gene name synonym)|uniprotkb:GOLPH1(gene name synonym)|uniprotkb:ACBD3(gene name)|psi-mi:ACBD3(display_short)|uniprotkb:GCP60(gene name synonym)|uniprotkb:Acyl-CoA-binding domain-containing protein 3(gene name synonym)|uniprotkb:Golgi phosphoprotein 1(gene name synonym)|uniprotkb:Golgi complex-associated protein 1(gene name synonym)|uniprotkb:PBR- and PKA-associated protein 7(gene name synonym)|uniprotkb:Peripheral benzodiazepine receptor-associated protein PAP7(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302779|imex:IM-27647-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67917(transcript)|ensemblbacteria:CT_324(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84326|refseq:NP_219829.1|refseq:WP_009871671.1 refseq:NP_073572.2|dip:DIP-40673N|ensembl:ENSG00000182827(gene)|ensembl:ENST00000366812(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR009038(GOLD)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984|interpro:IPR036598|mint:Q9H3P7|rcsb pdb:2N72|rcsb pdb:2N73|rcsb pdb:5LZ1|rcsb pdb:5LZ3|rcsb pdb:5LZ6|rcsb pdb:5TDQ|rcsb pdb:6HLN|rcsb pdb:6HLT|rcsb pdb:6HLV|rcsb pdb:6HLW|rcsb pdb:6HM8|rcsb pdb:6HMV|reactome:R-HSA-432722 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561 rogid:jAaMXnoXG6RGj+lAgIYk1inXA6o9606 rigid:yDID0/eyWtb3ezHp4X3gzaUExYY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84326 uniprotkb:Q9Y4X5 intact:EBI-22302763|ensemblbacteria:AAC67917 intact:EBI-2514233|ensembl:ENSP00000369217|uniprotkb:Q9UEN0|uniprotkb:Q9H3T6|uniprotkb:O76026|uniprotkb:Q9UP39|uniprotkb:B2R6U3 psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name) psi-mi:ari1_human(display_long)|uniprotkb:Protein ariadne-1 homolog(gene name synonym)|uniprotkb:ARIH1(gene name)|psi-mi:ARIH1(display_short)|uniprotkb:ARI(gene name synonym)|uniprotkb:MOP6(gene name synonym)|uniprotkb:UBCH7BP(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-binding protein 1(gene name synonym)|uniprotkb:UbcH7-binding protein(gene name synonym)|uniprotkb:UbcM4-interacting protein(gene name synonym)|uniprotkb:HHARI(gene name synonym)|uniprotkb:H7-AP2(gene name synonym)|uniprotkb:Monocyte protein 6(gene name synonym)|uniprotkb:HUSSY-27(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302779|imex:IM-27647-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67917(transcript)|ensemblbacteria:CT_324(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84326|refseq:NP_219829.1|refseq:WP_009871671.1 ensembl:ENSG00000166233(gene)|ensembl:ENST00000379887(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097413"(Lewy body)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|interpro:IPR044066|mint:Q9Y4X5|rcsb pdb:1WD2|rcsb pdb:2M9Y|rcsb pdb:4KBL|rcsb pdb:4KC9|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5S|reactome:R-HSA-1169408|go:"GO:0016567"(protein ubiquitination)|refseq:NP_005735.2|dip:DIP-53626N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561 rogid:4au2wa0c7NccURO3aKdmKN0U3PE9606 rigid:yDID0/eyWtb3ezHp4X3gzaUExYY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84326 uniprotkb:Q6NUM6 intact:EBI-22302763|ensemblbacteria:AAC67917 intact:EBI-12847032|ensembl:ENSP00000482502|uniprotkb:A6NG09|uniprotkb:B4DFY2|uniprotkb:Q3KQX2|uniprotkb:A0A087WZB2 psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name) psi-mi:tyw1b_human(display_long)|uniprotkb:TYW1B(gene name)|psi-mi:TYW1B(display_short)|uniprotkb:RSAFD2(gene name synonym)|uniprotkb:Radical S-adenosyl methionine and flavodoxin domain-containing protein 2(gene name synonym)|uniprotkb:tRNA wybutosine-synthesizing protein 1 homolog B(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302779|imex:IM-27647-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67917(transcript)|ensemblbacteria:CT_324(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84326|refseq:NP_219829.1|refseq:WP_009871671.1 ensembl:ENSG00000277149(gene)|ensembl:ENST00000620995(transcript)|go:"GO:0010181"(FMN binding)|go:"GO:0031591"(wybutosine biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0102521"(tRNA-4-demethylwyosine synthase activity)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR007197(Radical SAM)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR013917(Wyosine base formation)|interpro:IPR029039|mint:Q6NUM6|refseq:NP_001138912.2 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561 rogid:fIFV8S42LjKaRydFyQerBEg/lps9606 rigid:yDID0/eyWtb3ezHp4X3gzaUExYY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84326 uniprotkb:O43719 intact:EBI-22302763|ensemblbacteria:AAC67917 intact:EBI-720468|uniprotkb:Q59G06|uniprotkb:Q99730|uniprotkb:D3DWG9|intact:EBI-28971035|ensembl:ENSP00000218364|ensembl:ENSP00000442699 psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name) psi-mi:htsf1_human(display_long)|uniprotkb:HTATSF1(gene name)|psi-mi:HTATSF1(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302779|imex:IM-27647-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67917(transcript)|ensemblbacteria:CT_324(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84326|refseq:NP_219829.1|refseq:WP_009871671.1 ensembl:ENSP00000218364|ensembl:ENSP00000442699|refseq:NP_001156752.1|refseq:NP_055315.2|refseq:XP_005262461.1|dip:DIP-42095N|ensembl:ENSG00000102241(gene)|ensembl:ENST00000218364(transcript)|ensembl:ENST00000535601(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0019079"(viral genome replication)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034392|interpro:IPR034393|interpro:IPR035979|mint:O43719|rcsb pdb:2DIT|rcsb pdb:6N3D|rcsb pdb:6N3E|rcsb pdb:6N3F|rcsb pdb:6NSX|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561 rogid:PttL+7D+505QAmcHRGNsc40haPY9606 rigid:yDID0/eyWtb3ezHp4X3gzaUExYY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84326 uniprotkb:Q9BT78 intact:EBI-22302763|ensemblbacteria:AAC67917 intact:EBI-742413|uniprotkb:Q561W7|uniprotkb:Q9NW31|uniprotkb:Q9Y677|uniprotkb:B3KN88|ensembl:ENSP00000264389|uniprotkb:B3KST5 psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name) psi-mi:csn4_human(display_long)|uniprotkb:COPS4(gene name)|psi-mi:COPS4(display_short)|uniprotkb:CSN4(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 4(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302779|imex:IM-27647-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67917(transcript)|ensemblbacteria:CT_324(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84326|refseq:NP_219829.1|refseq:WP_009871671.1 ensembl:ENSG00000138663(gene)|refseq:NP_057213.2|refseq:NP_001244935.1|go:"GO:0016607"(nuclear speck)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0030054"(cell junction)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|interpro:IPR041406|mint:Q9BT78|rcsb pdb:4D0P|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-9013422|ensembl:ENST00000264389(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|refseq:NP_001317656.1|dip:DIP-34516N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561 rogid:onrZiPzG+bZvycmpDTZMtkPzCfQ9606 rigid:yDID0/eyWtb3ezHp4X3gzaUExYY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84326 uniprotkb:Q9UNS2 intact:EBI-22302763|ensemblbacteria:AAC67917 intact:EBI-350590|uniprotkb:O43191|uniprotkb:Q7LDR6|uniprotkb:B2R683|ensembl:ENSP00000268717|uniprotkb:B4DY81 psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name) psi-mi:csn3_human(display_long)|uniprotkb:COPS3(gene name)|psi-mi:COPS3(display_short)|uniprotkb:CSN3(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 3(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302779|imex:IM-27647-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67917(transcript)|ensemblbacteria:CT_324(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84326|refseq:NP_219829.1|refseq:WP_009871671.1 refseq:NP_001186054.1|refseq:NP_003644.2|ensembl:ENSG00000141030(gene)|ensembl:ENST00000268717(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009416"(response to light stimulus)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036390|interpro:IPR037753|mint:Q9UNS2|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|rcsb pdb:6R6H|refseq:NP_001303283.1|refseq:NP_001303284.1|refseq:NP_001303285.1|refseq:NP_001303286.1|refseq:NP_001303287.1|refseq:XP_005256894.1|dip:DIP-32478N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561 rogid:z6E/tPEo/ksVxD5Yyfo89t+ww989606 rigid:yDID0/eyWtb3ezHp4X3gzaUExYY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84326 uniprotkb:P61201 intact:EBI-22302763|ensemblbacteria:AAC67917 intact:EBI-1050386|uniprotkb:O88950|uniprotkb:Q15647|uniprotkb:Q6FGP4|uniprotkb:Q9BY54|uniprotkb:Q9R249|uniprotkb:Q9UNI2|uniprotkb:Q9UNQ5|ensembl:ENSP00000373553 psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name) psi-mi:csn2_human(display_long)|uniprotkb:JAB1-containing signalosome subunit 2(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 15(gene name synonym)|uniprotkb:Alien homolog(gene name synonym)|uniprotkb:COPS2(gene name)|psi-mi:COPS2(display_short)|uniprotkb:CSN2(gene name synonym)|uniprotkb:TRIP15(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302779|imex:IM-27647-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67917(transcript)|ensemblbacteria:CT_324(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84326|refseq:NP_219829.1|refseq:WP_009871671.1 refseq:NP_001137359.1|refseq:NP_004227.1|ensembl:ENSG00000166200(gene)|ensembl:ENST00000388901(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000338"(protein deneddylation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR036390|interpro:IPR037750|mint:P61201|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6A73|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-9013422|dip:DIP-42076N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561 rogid:MrlEHktIBvvcQux7Z7kqYJYgbbs9606 rigid:yDID0/eyWtb3ezHp4X3gzaUExYY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84326 uniprotkb:Q13098 intact:EBI-22302763|ensemblbacteria:AAC67917 intact:EBI-725197|uniprotkb:Q8NA10|uniprotkb:Q9BWL1|ensembl:ENSP00000302873 psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name) psi-mi:csn1_human(display_long)|uniprotkb:JAB1-containing signalosome subunit 1(gene name synonym)|uniprotkb:G protein pathway suppressor 1(gene name synonym)|uniprotkb:Protein MFH(gene name synonym)|uniprotkb:GPS1(gene name)|psi-mi:GPS1(display_short)|uniprotkb:COPS1(gene name synonym)|uniprotkb:CSN1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302779|imex:IM-27647-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67917(transcript)|ensemblbacteria:CT_324(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84326|refseq:NP_219829.1|refseq:WP_009871671.1 refseq:NP_004118.3|refseq:NP_997657.1|ensembl:ENSG00000169727(gene)|ensembl:ENST00000306823(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR019585|interpro:IPR033008|interpro:IPR036390|mint:Q13098|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|go:"GO:0005829"(cytosol)|go:"GO:0007254"(JNK cascade)|go:"GO:0008180"(COP9 signalosome)|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-9013422|refseq:NP_001308021.1|refseq:XP_016880023.1|dip:DIP-42077N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561 rogid:OMWZ67qcgKTM0R/hy8L2oCa3cpo9606 rigid:yDID0/eyWtb3ezHp4X3gzaUExYY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84326 uniprotkb:P28331 intact:EBI-22302763|ensemblbacteria:AAC67917 intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3 psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name) psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22302779|imex:IM-27647-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67917(transcript)|ensemblbacteria:CT_324(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84326|refseq:NP_219829.1|refseq:WP_009871671.1 refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561 rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606 rigid:yDID0/eyWtb3ezHp4X3gzaUExYY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84251 uniprotkb:P10586 intact:EBI-22302798|ensemblbacteria:AAC67842 intact:EBI-7188069|ensembl:ENSP00000353030|uniprotkb:Q5T022|uniprotkb:Q5W9G2|intact:MINT-1189049|uniprotkb:D3DPX7|uniprotkb:Q5T021|uniprotkb:D3DPX6|uniprotkb:Q86WS0 psi-mi:o84251_chltr(display_long)|uniprotkb:CT_249(locus name) psi-mi:ptprf_human(display_long)|uniprotkb:PTPRF(gene name)|psi-mi:PTPRF(display_short)|uniprotkb:LAR(gene name synonym)|uniprotkb:Leukocyte common antigen related(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302805|imex:IM-27647-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67842(transcript)|ensemblbacteria:CT_249(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84251|refseq:NP_219754.1|refseq:WP_010725138.1 ensembl:ENSG00000142949(gene)|ensembl:ENST00000359947(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0008201"(heparin binding)|go:"GO:0016477"(cell migration)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0035373"(chondroitin sulfate proteoglycan binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1900121"(negative regulation of receptor binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|mint:P10586|rcsb pdb:1LAR|rcsb pdb:2DJU|rcsb pdb:2DN7|rcsb pdb:2EDX|rcsb pdb:2EDY|rcsb pdb:2YD5|rcsb pdb:2YD8|rcsb pdb:4N5U|rcsb pdb:6KR4|rcsb pdb:6TPT|rcsb pdb:6TPU|rcsb pdb:6TPV|rcsb pdb:6TPW|reactome:R-HSA-388844|reactome:R-HSA-8849932|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|refseq:NP_002831.2|refseq:NP_569707.2 - - comment:mint|comment:homomint figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:Qrz9/Xb6BG0jCeKOJb19bBygXxo272561 rogid:JLPH3tIxOkyVmJ0mZsBZ+TanLVk9606 rigid:w0x7du7EkeaypeTnQJiNbSV1b7Q false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84251 uniprotkb:Q9Y3E5 intact:EBI-22302798|ensemblbacteria:AAC67842 intact:EBI-1056751|uniprotkb:Q9NTE5|uniprotkb:B3KUY4|ensembl:ENSP00000376758|ensembl:ENSP00000464327 psi-mi:o84251_chltr(display_long)|uniprotkb:CT_249(locus name) psi-mi:pth2_human(display_long)|uniprotkb:PTRH2(gene name)|psi-mi:PTRH2(display_short)|uniprotkb:BIT1(gene name synonym)|uniprotkb:PTH2(gene name synonym)|uniprotkb:CGI-147(orf name)|uniprotkb:Bcl-2 inhibitor of transcription 1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302805|imex:IM-27647-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67842(transcript)|ensemblbacteria:CT_249(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84251|refseq:NP_219754.1|refseq:WP_010725138.1 refseq:NP_057161.1|refseq:NP_001015509.1|refseq:XP_011523189.1|ensembl:ENSG00000141378(gene)|ensembl:ENST00000393038(transcript)|ensembl:ENST00000470557(transcript)|go:"GO:0004045"(aminoacyl-tRNA hydrolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:2000210"(positive regulation of anoikis)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002833(Peptidyl-tRNA hydrolase, PTH2)|interpro:IPR023476|mint:Q9Y3E5|rcsb pdb:1Q7S|reactome:R-HSA-5689880 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:Qrz9/Xb6BG0jCeKOJb19bBygXxo272561 rogid:E0QOhTNtGBt5CQ3gPebnOhoKvdU9606 rigid:w0x7du7EkeaypeTnQJiNbSV1b7Q false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84251 uniprotkb:Q9H8H3 intact:EBI-22302798|ensemblbacteria:AAC67842 intact:EBI-1390168|uniprotkb:Q9H7R3|uniprotkb:Q9UHZ7|uniprotkb:Q9Y422|ensembl:ENSP00000331787|ensembl:ENSP00000447542|ensembl:ENSP00000448785 psi-mi:o84251_chltr(display_long)|uniprotkb:CT_249(locus name) psi-mi:met7a_human(display_long)|uniprotkb:Protein AAM-B(gene name synonym)|uniprotkb:METTL7A(gene name)|psi-mi:METTL7A(display_short)|uniprotkb:PRO0066(orf name)|uniprotkb:UNQ1902/PRO4348(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302805|imex:IM-27647-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67842(transcript)|ensemblbacteria:CT_249(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84251|refseq:NP_219754.1|refseq:WP_010725138.1 refseq:NP_054752.3|refseq:XP_006719395.1|ensembl:ENSG00000185432(gene)|ensembl:ENST00000332160(transcript)|ensembl:ENST00000547104(transcript)|ensembl:ENST00000548553(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0032259"(methylation)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|mint:Q9H8H3|reactome:R-HSA-6798695 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:Qrz9/Xb6BG0jCeKOJb19bBygXxo272561 rogid:b8PnE+BClVn1MzOlg0uIaqDSOaU9606 rigid:w0x7du7EkeaypeTnQJiNbSV1b7Q false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84251 uniprotkb:P54709 intact:EBI-22302798|ensemblbacteria:AAC67842 intact:EBI-1054481|uniprotkb:B7Z1N7|ensembl:ENSP00000286371 psi-mi:o84251_chltr(display_long)|uniprotkb:CT_249(locus name) psi-mi:at1b3_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-3(gene name synonym)|uniprotkb:ATP1B3(gene name)|psi-mi:ATP1B3(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302805|imex:IM-27647-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67842(transcript)|ensemblbacteria:CT_249(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84251|refseq:NP_219754.1|refseq:WP_010725138.1 refseq:NP_001670.1|ensembl:ENSG00000069849(gene)|ensembl:ENST00000286371(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR038702|mint:P54709|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|dip:DIP-50717N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:Qrz9/Xb6BG0jCeKOJb19bBygXxo272561 rogid:M7gSVe1bjKF7LqCZh/raoHBvp7M9606 rigid:w0x7du7EkeaypeTnQJiNbSV1b7Q false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84251 uniprotkb:Q9HAV0 intact:EBI-22302798|ensemblbacteria:AAC67842 intact:EBI-358539|uniprotkb:B3KMH5|uniprotkb:D3DNR8|ensembl:ENSP00000501882|ensembl:ENSP00000502628|ensembl:ENSP00000232564 psi-mi:o84251_chltr(display_long)|uniprotkb:CT_249(locus name) psi-mi:gbb4_human(display_long)|uniprotkb:GNB4(gene name)|psi-mi:GNB4(display_short)|uniprotkb:Transducin beta chain 4(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302805|imex:IM-27647-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67842(transcript)|ensemblbacteria:CT_249(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84251|refseq:NP_219754.1|refseq:WP_010725138.1 refseq:NP_067642.1|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|reactome:R-HSA-456926|ensembl:ENSG00000114450(gene)|ensembl:ENST00000232564(transcript)|ensembl:ENST00000674862(transcript)|ensembl:ENST00000676128(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0021762"(substantia nigra development)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9HAV0|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-381676|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|refseq:XP_006713784.1|refseq:XP_005247749.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:Qrz9/Xb6BG0jCeKOJb19bBygXxo272561 rogid:L6hFuZe1Luk8YTFW+posXDa2Qj49606 rigid:w0x7du7EkeaypeTnQJiNbSV1b7Q false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84251 uniprotkb:Q9NX61 intact:EBI-22302798|ensemblbacteria:AAC67842 intact:EBI-6138599|uniprotkb:Q7L2Y1|uniprotkb:B3KUE0|uniprotkb:G5E9M6|ensembl:ENSP00000162044 psi-mi:o84251_chltr(display_long)|uniprotkb:CT_249(locus name) psi-mi:t161a_human(display_long)|uniprotkb:TMEM161A(gene name)|psi-mi:TMEM161A(display_short)|uniprotkb:Adaptive response to oxidative stress protein 29(gene name synonym)|uniprotkb:UNQ582/PRO1152(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302805|imex:IM-27647-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67842(transcript)|ensemblbacteria:CT_249(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84251|refseq:NP_219754.1|refseq:WP_010725138.1 refseq:NP_060284.1|refseq:NP_001243695.1|ensembl:ENSG00000064545(gene)|ensembl:ENST00000162044(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|interpro:IPR019395|mint:Q9NX61 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:Qrz9/Xb6BG0jCeKOJb19bBygXxo272561 rogid:VVl+h1R9nV0jkQjR4xUzsUe4qKU9606 rigid:w0x7du7EkeaypeTnQJiNbSV1b7Q false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84251 uniprotkb:Q9H0P0 intact:EBI-22302798|ensemblbacteria:AAC67842 intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5 psi-mi:o84251_chltr(display_long)|uniprotkb:CT_249(locus name) psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302805|imex:IM-27647-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67842(transcript)|ensemblbacteria:CT_249(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84251|refseq:NP_219754.1|refseq:WP_010725138.1 interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:Qrz9/Xb6BG0jCeKOJb19bBygXxo272561 rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606 rigid:w0x7du7EkeaypeTnQJiNbSV1b7Q false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84251 uniprotkb:Q9UBE0 intact:EBI-22302798|ensemblbacteria:AAC67842 intact:EBI-743154|ensembl:ENSP00000270225|uniprotkb:O95717|uniprotkb:Q9P020|uniprotkb:B2RDP5|uniprotkb:B3KMQ2|uniprotkb:F5GXX7|uniprotkb:G3XAK6 psi-mi:o84251_chltr(display_long)|uniprotkb:CT_249(locus name) psi-mi:sae1_human(display_long)|uniprotkb:Ubiquitin-like 1-activating enzyme E1A(gene name synonym)|uniprotkb:SAE1(gene name)|psi-mi:SAE1(display_short)|uniprotkb:AOS1(gene name synonym)|uniprotkb:UBLE1A(gene name synonym)|uniprotkb:SUA1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302805|imex:IM-27647-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67842(transcript)|ensemblbacteria:CT_249(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84251|refseq:NP_219754.1|refseq:WP_010725138.1 ensembl:ENSG00000142230(gene)|ensembl:ENST00000270225(transcript)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR035985|mint:Q9UBE0|rcsb pdb:1Y8Q|rcsb pdb:1Y8R|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:6CWY|rcsb pdb:6CWZ|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|refseq:NP_005491.1|refseq:NP_001139185.1|refseq:NP_001139186.1|dip:DIP-34587N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:Qrz9/Xb6BG0jCeKOJb19bBygXxo272561 rogid:8Az5p8NJ5XfF1pxbyynnYrQLFN89606 rigid:w0x7du7EkeaypeTnQJiNbSV1b7Q false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84251 uniprotkb:Q8WU67 intact:EBI-22302798|ensemblbacteria:AAC67842 intact:EBI-2876553|ensembl:ENSP00000289119|uniprotkb:B7Z5C2|uniprotkb:O43411|uniprotkb:B0YIV0 psi-mi:o84251_chltr(display_long)|uniprotkb:CT_249(locus name) psi-mi:abhd3_human(display_long)|uniprotkb:ABHD3(gene name)|psi-mi:ABHD3(display_short)|uniprotkb:Abhydrolase domain-containing protein 3(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302805|imex:IM-27647-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67842(transcript)|ensemblbacteria:CT_249(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84251|refseq:NP_219754.1|refseq:WP_010725138.1 reactome:R-HSA-1483191|ensembl:ENSG00000158201(gene)|ensembl:ENST00000289119(transcript)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|go:"GO:0052739"(phosphatidylserine 1-acylhydrolase activity)|go:"GO:0052740"(1-acyl-2-lysophosphatidylserine acylhydrolase activity)|go:"GO:0102567"|go:"GO:0102568"|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR029058|mint:Q8WU67|go:"GO:0008970"(phospholipase A1 activity)|refseq:NP_001295185.1|refseq:NP_001295186.1|refseq:NP_612213.2 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:Qrz9/Xb6BG0jCeKOJb19bBygXxo272561 rogid:QGMm0R1GsOz+kODPipFvZi1/tqg9606 rigid:w0x7du7EkeaypeTnQJiNbSV1b7Q false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84251 uniprotkb:P35610 intact:EBI-22302798|ensemblbacteria:AAC67842 intact:EBI-6621955|ensembl:ENSP00000356591|uniprotkb:A6NC40|uniprotkb:A8K3P4|uniprotkb:A9Z1V7|uniprotkb:B4DU95|uniprotkb:Q5T0X4|uniprotkb:Q8N1E4 psi-mi:o84251_chltr(display_long)|uniprotkb:CT_249(locus name) psi-mi:soat1_human(display_long)|uniprotkb:SOAT1(gene name)|psi-mi:SOAT1(display_short)|uniprotkb:ACACT(gene name synonym)|uniprotkb:ACACT1(gene name synonym)|uniprotkb:ACAT(gene name synonym)|uniprotkb:ACAT1(gene name synonym)|uniprotkb:SOAT(gene name synonym)|uniprotkb:STAT(gene name synonym)|uniprotkb:"Acyl-coenzyme A:cholesterol acyltransferase 1"(gene name synonym)|uniprotkb:Cholesterol acyltransferase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302805|imex:IM-27647-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67842(transcript)|ensemblbacteria:CT_249(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84251|refseq:NP_219754.1|refseq:WP_010725138.1 go:"GO:0010878"(cholesterol storage)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0034435"(cholesterol esterification)|go:"GO:0034736"(cholesterol O-acyltransferase activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042986"(positive regulation of amyloid precursor protein biosynthetic process)|interpro:IPR004299(Membrane bound O-acyl transferase, MBOAT)|ensembl:ENSG00000057252(gene)|interpro:IPR014371(Sterol O-acyltransferase, ACAT/DAG/ARE types)|interpro:IPR030687|mint:P35610|rcsb pdb:6L47|rcsb pdb:6L48|rcsb pdb:6P2J|rcsb pdb:6P2P|rcsb pdb:6VUM|reactome:R-HSA-8964038|ensembl:ENST00000367619(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0004772"(sterol O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0010742"(macrophage derived foam cell differentiation)|refseq:XP_011508213.1|refseq:NP_001239440.1|refseq:NP_001239441.1|refseq:NP_003092.4 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:Qrz9/Xb6BG0jCeKOJb19bBygXxo272561 rogid:jX8d8x9ZYOdpE2Vg+C5ECuX9zQQ9606 rigid:w0x7du7EkeaypeTnQJiNbSV1b7Q false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84362 uniprotkb:P03928 intact:EBI-22302824|ensemblbacteria:AAC67953 intact:EBI-3439833|intact:EBI-3450125|uniprotkb:Q34771|ensembl:ENSP00000355265 psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name) psi-mi:atp8_human(display_long)|uniprotkb:MT-ATP8(gene name)|psi-mi:MT-ATP8(display_short)|uniprotkb:ATP8(gene name synonym)|uniprotkb:ATPASE8(gene name synonym)|uniprotkb:MTATP8(gene name synonym)|uniprotkb:A6L(gene name synonym)|uniprotkb:F-ATPase subunit 8(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302831|imex:IM-27647-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67953(transcript)|ensemblbacteria:CT_357(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84362|refseq:NP_219866.1|refseq:WP_010725169.1 refseq:YP_003024030.1|ensembl:ENSG00000228253(gene)|ensembl:ENST00000361851(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR001421(ATPase, F0 complex, subunit 8, mitochondrial, Metazoan)|interpro:IPR039017|mint:P03928|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561 rogid:8LbAeHQBEFnML9W9QP2R2igsr0U9606 rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84362 uniprotkb:P56385 intact:EBI-22302824|ensemblbacteria:AAC67953 intact:EBI-2270000|uniprotkb:Q0D2L9|ensembl:ENSP00000306003 psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name) psi-mi:atp5i_human(display_long)|uniprotkb:ATP5ME(gene name)|psi-mi:ATP5ME(display_short)|uniprotkb:ATP5I(gene name synonym)|uniprotkb:ATP synthase membrane subunit e(gene name synonym)|uniprotkb:ATP5K(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302831|imex:IM-27647-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67953(transcript)|ensemblbacteria:CT_357(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84362|refseq:NP_219866.1|refseq:WP_010725169.1 refseq:NP_009031.1|ensembl:ENSG00000169020(gene)|ensembl:ENST00000304312(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR008386(ATPase, F0 complex, subunit E, mitochondrial)|mint:P56385|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561 rogid:NYpqzWQYASXwSwU/BYDTMU2tJjI9606 rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84362 uniprotkb:P56134 intact:EBI-22302824|ensemblbacteria:AAC67953 intact:EBI-712794|ensembl:ENSP00000292475|uniprotkb:O76079|uniprotkb:Q96L83|uniprotkb:Q9BTI8|uniprotkb:C9J8H9|uniprotkb:F8W7V3|intact:EBI-11047094|uniprotkb:Q6IBB3 psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name) psi-mi:atpk_human(display_long)|uniprotkb:ATP5MF(gene name)|psi-mi:ATP5MF(display_short)|uniprotkb:ATP synthase membrane subunit f(gene name synonym)|uniprotkb:ATP5J2(gene name synonym)|uniprotkb:ATP5JL(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302831|imex:IM-27647-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67953(transcript)|ensemblbacteria:CT_357(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84362|refseq:NP_219866.1|refseq:WP_010725169.1 ensembl:ENSG00000241468(gene)|ensembl:ENST00000292475(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR019344|mint:P56134|reactome:R-HSA-163210|reactome:R-HSA-8949613|refseq:NP_001003713.1|refseq:NP_004880.1|refseq:NP_001003714.1|refseq:NP_001034267.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561 rogid:+WS7rjFef6JE+mlZ4Q8TF2A+G0E9606 rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84362 uniprotkb:O75947 intact:EBI-22302824|ensemblbacteria:AAC67953 intact:EBI-724024|ensembl:ENSP00000301587|uniprotkb:Q9H3J4|uniprotkb:B2R5L6 psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name) psi-mi:atp5h_human(display_long)|uniprotkb:ATP5PD(gene name)|psi-mi:ATP5PD(display_short)|uniprotkb:ATP synthase peripheral stalk subunit d(gene name synonym)|uniprotkb:ATP5H(gene name synonym)|uniprotkb:My032(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302831|imex:IM-27647-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67953(transcript)|ensemblbacteria:CT_357(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84362|refseq:NP_219866.1|refseq:WP_010725169.1 refseq:NP_001003785.1|refseq:NP_006347.1|ensembl:ENSG00000167863(gene)|ensembl:ENST00000301587(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR008689(ATPase, F0 complex, subunit D, mitochondrial)|interpro:IPR036228|mint:O75947|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561 rogid:GFk/w7iWIjum9BpZs8ZlPrM5kBs9606 rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84362 uniprotkb:P30049 intact:EBI-22302824|ensemblbacteria:AAC67953 intact:EBI-1049505|uniprotkb:Q6FG90|uniprotkb:D6W5Y3|ensembl:ENSP00000215375|ensembl:ENSP00000378995|ensembl:ENSP00000464863 psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name) psi-mi:atpd_human(display_long)|uniprotkb:ATP5F1D(gene name)|psi-mi:ATP5F1D(display_short)|uniprotkb:ATP synthase F1 subunit delta(gene name synonym)|uniprotkb:ATP5D(gene name synonym)|uniprotkb:F-ATPase delta subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302831|imex:IM-27647-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67953(transcript)|ensemblbacteria:CT_357(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84362|refseq:NP_219866.1|refseq:WP_010725169.1 refseq:NP_001001975.1|refseq:NP_001678.1|ensembl:ENSG00000099624(gene)|ensembl:ENST00000215375(transcript)|ensembl:ENST00000395633(transcript)|ensembl:ENST00000591660(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009060"(aerobic respiration)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046688"(response to copper ion)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR001469(ATPase, F1 complex, delta/epsilon subunit)|interpro:IPR020546|interpro:IPR036771|interpro:IPR036794|mint:P30049|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561 rogid:OA8if7wpjwV6hkkaLqPyz6YDljc9606 rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84362 uniprotkb:Q96NT0 intact:EBI-22302824|ensemblbacteria:AAC67953 intact:EBI-2810325|uniprotkb:B4DJ47|uniprotkb:Q9BR88|ensembl:ENSP00000259229 psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name) psi-mi:cc115_human(display_long)|uniprotkb:CCDC115(gene name)|psi-mi:CCDC115(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302831|imex:IM-27647-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67953(transcript)|ensemblbacteria:CT_357(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84362|refseq:NP_219866.1|refseq:WP_010725169.1 refseq:NP_115733.2|mint:Q96NT0|reactome:R-HSA-8980692|ensembl:ENSG00000136710(gene)|ensembl:ENST00000259229(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0016020"(membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|go:"GO:1905146"(lysosomal protein catabolic process)|interpro:IPR040357|refseq:NP_001308047.1|refseq:NP_001308048.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561 rogid:cUCb36pVMieoV7ZwXQPtD/kIAXY9606 rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84362 uniprotkb:P24539 intact:EBI-22302824|ensemblbacteria:AAC67953 intact:EBI-1044810|uniprotkb:Q9BQ68|uniprotkb:Q9BRU8|ensembl:ENSP00000358737 psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name) psi-mi:at5f1_human(display_long)|uniprotkb:ATP5PB(gene name)|psi-mi:ATP5PB(display_short)|uniprotkb:ATP synthase peripheral stalk-membrane subunit b(gene name synonym)|uniprotkb:"ATP synthase proton-transporting mitochondrial F(0) complex subunit B1"(gene name synonym)|uniprotkb:ATP synthase subunit b(gene name synonym)|uniprotkb:ATP5F1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302831|imex:IM-27647-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67953(transcript)|ensemblbacteria:CT_357(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84362|refseq:NP_219866.1|refseq:WP_010725169.1 refseq:NP_001679.2|ensembl:ENSG00000116459(gene)|ensembl:ENST00000369722(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0021762"(substantia nigra development)|interpro:IPR008688(ATPase, F0 complex, subunit B, mitochondrial)|interpro:IPR013837(ATPase, F0 complex subunit B, mitochondrial, metazoa)|mint:P24539|reactome:R-HSA-163210|reactome:R-HSA-8949613|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561 rogid:n1HuorsLzONcID7ccOL9qEsODLE9606 rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84362 uniprotkb:Q06136 intact:EBI-22302824|ensemblbacteria:AAC67953 intact:EBI-3909166|uniprotkb:B2R5Y1|ensembl:ENSP00000494352|uniprotkb:B4DMX0 psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name) psi-mi:kdsr_human(display_long)|uniprotkb:KDSR(gene name)|psi-mi:KDSR(display_short)|uniprotkb:FVT1(gene name synonym)|uniprotkb:3-dehydrosphinganine reductase(gene name synonym)|uniprotkb:Follicular variant translocation protein 1(gene name synonym)|uniprotkb:SDR35C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 35C member 1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302831|imex:IM-27647-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67953(transcript)|ensemblbacteria:CT_357(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84362|refseq:NP_219866.1|refseq:WP_010725169.1 refseq:NP_002026.1|ensembl:ENST00000645214(transcript)|ensembl:ENSG00000119537(gene)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006666"(3-keto-sphinganine metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0047560"(3-dehydrosphinganine reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q06136|reactome:R-HSA-1660661 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561 rogid:Qeo5s672s/qK8CE52sS1Pr01kFY9606 rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84362 uniprotkb:Q96G23 intact:EBI-22302824|ensemblbacteria:AAC67953 intact:EBI-1057080|uniprotkb:Q9HD96|uniprotkb:Q9NW79|uniprotkb:D3DV06|uniprotkb:Q5SZE5|ensembl:ENSP00000271688|ensembl:ENSP00000357950 psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name) psi-mi:cers2_human(display_long)|uniprotkb:CERS2(gene name)|psi-mi:CERS2(display_short)|uniprotkb:TMSG1(gene name synonym)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:SP260(gene name synonym)|uniprotkb:LASS2(gene name synonym)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302831|imex:IM-27647-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67953(transcript)|ensemblbacteria:CT_357(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84362|refseq:NP_219866.1|refseq:WP_010725169.1 refseq:XP_011507754.1|refseq:NP_071358.1|refseq:NP_859530.1|ensembl:ENSG00000143418(gene)|ensembl:ENST00000271688(transcript)|ensembl:ENST00000368954(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q96G23|reactome:R-HSA-1660661|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561 rogid:Eqxvp+41fFXPr+hpqRQsLB6Lq4M9606 rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84362 uniprotkb:O75787 intact:EBI-22302824|ensemblbacteria:AAC67953 intact:EBI-2512037|ensembl:ENSP00000490083|uniprotkb:B7Z9I3|uniprotkb:Q8NG15|uniprotkb:Q8NBP3|uniprotkb:Q5QTQ7|uniprotkb:Q9UG89|uniprotkb:Q96FV6|uniprotkb:Q9H2P8|uniprotkb:Q96LB5|uniprotkb:Q6T7F5 psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name) psi-mi:renr_human(display_long)|uniprotkb:ATP6AP2(gene name)|psi-mi:ATP6AP2(display_short)|uniprotkb:ATP6IP2(gene name synonym)|uniprotkb:CAPER(gene name synonym)|uniprotkb:ELDF10(gene name synonym)|uniprotkb:Renin/prorenin receptor(gene name synonym)|uniprotkb:"ATPase H(+)-transporting lysosomal accessory protein 2"(gene name synonym)|uniprotkb:"ATPase H(+)-transporting lysosomal-interacting protein 2"(gene name synonym)|uniprotkb:Vacuolar ATP synthase membrane sector-associated protein M8-9(gene name synonym)|uniprotkb:N14F(gene name synonym)|uniprotkb:Embryonic liver differentiation factor 10(gene name synonym)|uniprotkb:HT028(orf name)|uniprotkb:MSTP009(orf name)|uniprotkb:PSEC0072(orf name)|uniprotkb:ER-localized type I transmembrane adapter(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302831|imex:IM-27647-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67953(transcript)|ensemblbacteria:CT_357(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84362|refseq:NP_219866.1|refseq:WP_010725169.1 ensembl:ENSG00000182220(gene)|ensembl:ENST00000636580(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002003"(angiotensin maturation)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0021626"(central nervous system maturation)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030424"(axon)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032914"(positive regulation of transforming growth factor beta1 production)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048069"(eye pigmentation)|go:"GO:0060323"(head morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR012493(Renin receptor-like)|mint:O75787|rcsb pdb:3LBS|rcsb pdb:3LC8|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-2022377|reactome:R-HSA-6798695|refseq:NP_005756.2 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561 rogid:v4lEPX23LdYqPi8dQX4MZG+tQZg9606 rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84362 uniprotkb:P61421 intact:EBI-22302824|ensemblbacteria:AAC67953 intact:EBI-954063|ensembl:ENSP00000290949|uniprotkb:P12953|uniprotkb:Q02547 psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name) psi-mi:va0d1_human(display_long)|uniprotkb:Vacuolar proton pump subunit d 1(gene name synonym)|uniprotkb:V-ATPase AC39 subunit(gene name synonym)|uniprotkb:V-ATPase 40 kDa accessory protein(gene name synonym)|uniprotkb:32 kDa accessory protein(gene name synonym)|uniprotkb:ATP6V0D1(gene name)|psi-mi:ATP6V0D1(display_short)|uniprotkb:ATP6D(gene name synonym)|uniprotkb:VPATPD(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302831|imex:IM-27647-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67953(transcript)|ensemblbacteria:CT_357(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84362|refseq:NP_219866.1|refseq:WP_010725169.1 ensembl:ENSG00000159720(gene)|ensembl:ENST00000290949(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|mint:P61421|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-381038|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|go:"GO:0016324"(apical plasma membrane)|refseq:NP_004682.2|dip:DIP-47435N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561 rogid:3a/yIxEF9LMwAZUR3npGQrw8xNo9606 rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84362 uniprotkb:Q93050 intact:EBI-22302824|ensemblbacteria:AAC67953 intact:EBI-2891238|ensembl:ENSP00000342951|uniprotkb:Q8N5G7|uniprotkb:Q9NSX0|intact:EBI-4324496|uniprotkb:B7Z3B7 psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name) psi-mi:vpp1_human(display_long)|uniprotkb:ATP6V0A1(gene name)|psi-mi:ATP6V0A1(display_short)|uniprotkb:ATP6N1(gene name synonym)|uniprotkb:ATP6N1A(gene name synonym)|uniprotkb:VPP1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1(gene name synonym)|uniprotkb:Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit(gene name synonym)|uniprotkb:Vacuolar proton pump subunit 1(gene name synonym)|uniprotkb:Vacuolar adenosine triphosphatase subunit Ac116(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302831|imex:IM-27647-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67953(transcript)|ensemblbacteria:CT_357(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84362|refseq:NP_219866.1|refseq:WP_010725169.1 ensembl:ENSG00000033627(gene)|ensembl:ENST00000343619(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1901998"(toxin transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|mint:Q93050|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-6798695|reactome:R-HSA-77387|interpro:IPR026028|reactome:R-HSA-917977|reactome:R-HSA-983712|refseq:NP_001123492.1|refseq:NP_001123493.1|refseq:NP_005168.2 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561 rogid:3htDhXCA9potj7i32HoA2j3Sfqw9606 rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84362 uniprotkb:Q9Y487 intact:EBI-22302824|ensemblbacteria:AAC67953 intact:EBI-988630|ensembl:ENSP00000332247|uniprotkb:Q6NUM0|uniprotkb:A8K026 psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name) psi-mi:vpp2_human(display_long)|uniprotkb:Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2(gene name synonym)|uniprotkb:"Lysosomal H(+)-transporting ATPase V0 subunit a2"(gene name synonym)|uniprotkb:TJ6(gene name synonym)|uniprotkb:ATP6V0A2(gene name)|psi-mi:ATP6V0A2(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302831|imex:IM-27647-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67953(transcript)|ensemblbacteria:CT_357(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84362|refseq:NP_219866.1|refseq:WP_010725169.1 ensembl:ENSG00000185344(gene)|ensembl:ENST00000330342(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006955"(immune response)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051117"(ATPase binding)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|mint:Q9Y487|refseq:NP_036595.2|reactome:R-HSA-1222556|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-983712 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561 rogid:I4UxvwiAe4ObvfgL15K2lzNKuOA9606 rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:P49354 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-602336|uniprotkb:Q9UDC1|uniprotkb:A6NJW0|uniprotkb:Q53XJ9|ensembl:ENSP00000303423 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:fnta_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:FNTA(gene name)|psi-mi:FNTA(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_002018.1|ensembl:ENSG00000168522(gene)|ensembl:ENST00000302279(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0030548"(acetylcholine receptor regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090044"(positive regulation of tubulin deacetylation)|go:"GO:0090045"(positive regulation of deacetylase activity)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|mint:P49354|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-111465|reactome:R-HSA-2514859|reactome:R-HSA-9648002 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:2VOoFRlMYQR1v9oiOKl1sktjaa09606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:O43251 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-746056|uniprotkb:Q5TF71|uniprotkb:Q6IC09|uniprotkb:Q8TD00|uniprotkb:Q8WYB1|uniprotkb:Q96DZ6|uniprotkb:Q96NL7|uniprotkb:Q9UGW4|uniprotkb:Q9UH33|uniprotkb:Q0VH35|uniprotkb:A4F5G8|uniprotkb:A8K5Z5|uniprotkb:Q0PRL5|uniprotkb:B0QYY8|uniprotkb:B0QYY9 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:rfox2_human(display_long)|uniprotkb:FOX2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001026865.1|refseq:NP_001076045.1|refseq:NP_001076046.1|refseq:NP_055124.1|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:2CQ3|reactome:R-HSA-6803529|interpro:IPR025670|refseq:XP_005261494.1|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43251|interpro:IPR035979|refseq:NP_001076047.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:eIocECpScMWGhrZslIle29WUyKs9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:Q96EB6 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-1802965|uniprotkb:Q2XNF6|uniprotkb:Q5JVQ0|uniprotkb:Q9GZR9|uniprotkb:Q9Y6F0|ensembl:ENSP00000212015 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:sir1_human(display_long)|uniprotkb:NAD-dependent protein deacylase sirtuin-1(gene name synonym)|uniprotkb:SIRT1(gene name)|psi-mi:SIRT1(display_short)|uniprotkb:SIR2L1(gene name synonym)|uniprotkb:SIR2-like protein 1(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_001135970.1|refseq:NP_036370.2|refseq:NP_001300978.1|dip:DIP-29757N|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q96EB6|rcsb pdb:4I5I|rcsb pdb:4IF6|rcsb pdb:4IG9|rcsb pdb:4KXQ|rcsb pdb:4ZZH|rcsb pdb:4ZZI|rcsb pdb:4ZZJ|rcsb pdb:5BTR|reactome:R-HSA-3371453|reactome:R-HSA-400253|reactome:R-HSA-427359|reactome:R-HSA-9617629|reactome:R-HSA-9707616|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007517"(muscle organ development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000096717(gene)|ensembl:ENST00000212015(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001542"(ovulation from ovarian follicle)|go:"GO:0001650"(fibrillar center)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002039"(p53 binding)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031393"(negative regulation of prostaglandin biosynthetic process)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031648"(protein destabilization)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034391"(regulation of smooth muscle cell apoptotic process)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035358"(regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042393"(histone binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042595"(behavioral response to starvation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043398"(HLH domain binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070857"(regulation of bile acid biosynthetic process)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0044321"(response to leptin)|go:"GO:0071441"(negative regulation of histone H3-K14 acetylation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0106230"(protein depropionylation)|go:"GO:0106231"(protein-propionyllysine depropionylase activity)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904179"(positive regulation of adipose tissue development)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000111"(positive regulation of macrophage apoptotic process)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|go:"GO:2000619"(negative regulation of histone H4-K16 acetylation)|go:"GO:2000655"(negative regulation of cellular response to testosterone stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:h3zVepuhRhzlINCluVuAn71Btjc9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:Q6IA86 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-2680411|uniprotkb:Q53GZ0|uniprotkb:Q8N5C2|uniprotkb:Q9H9N0|uniprotkb:Q96GV4|uniprotkb:Q687Y8|uniprotkb:Q9NV81|uniprotkb:Q96PI7|uniprotkb:B4DTG0|uniprotkb:A8KAI6|uniprotkb:B4DXP0|uniprotkb:E7EP23|uniprotkb:E9PCX0|intact:EBI-28972003|ensembl:ENSP00000350967 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:elp2_human(display_long)|uniprotkb:STATIP1(gene name synonym)|uniprotkb:SHINC-2(gene name synonym)|uniprotkb:STAT3-interacting protein 1(gene name synonym)|uniprotkb:ELP2(gene name)|psi-mi:ELP2(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 ensembl:ENST00000350494|ensembl:ENSP00000316051|ensembl:ENST00000351393|ensembl:ENSP00000257191|ensembl:ENSP00000350967|ensembl:ENST00000423854|ensembl:ENSP00000391202|ensembl:ENST00000442325|ensembl:ENSP00000414851|ensembl:ENST00000539560|ensembl:ENSP00000443555|ensembl:ENST00000542824|ensembl:ENSP00000443800|refseq:NP_001229804.1|refseq:NP_001229805.1|refseq:NP_001229806.1|refseq:NP_001229807.1|refseq:NP_001229808.1|refseq:NP_060725.1|dip:DIP-56235N|ensembl:ENSG00000134759(gene)|ensembl:ENST00000358232(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0046425"(regulation of receptor signaling pathway via JAK-STAT)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037289|mint:Q6IA86|reactome:R-HSA-3214847 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:CkQQYyJ00MHOYXKhvVnwgAhdP2M9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:O75147 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-1223896|uniprotkb:A4KVA5|uniprotkb:Q96IW3|intact:EBI-7903201|intact:MINT-8415345|uniprotkb:A4KVA4|uniprotkb:S4R3M6|intact:EBI-28983679|ensembl:ENSP00000385636|uniprotkb:A0A024R468 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:obsl1_human(display_long)|uniprotkb:OBSL1(gene name)|psi-mi:OBSL1(display_short)|uniprotkb:KIAA0657(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_001166879.1|refseq:NP_056126.1|refseq:NP_001166902.1|ensembl:ENST00000373873|ensembl:ENSP00000362980|ensembl:ENSP00000385636|ensembl:ENST00000603926|ensembl:ENSP00000474519|dip:DIP-38340N|ensembl:ENSG00000124006(gene)|ensembl:ENST00000404537(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010842"(retina layer formation)|go:"GO:0014704"(intercalated disc)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:1990393"(3M complex)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:O75147|rcsb pdb:2CPC|rcsb pdb:2E6P|rcsb pdb:2E6Q|rcsb pdb:2LU7|rcsb pdb:2LVC|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:3KNB|rcsb pdb:5FM5|reactome:R-HSA-8951664 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:HFxqB+AxsXH/zWXgCj/ODfSmqQQ9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:Q9Y2R5 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-1046443|ensembl:ENSP00000285298|uniprotkb:Q86X15 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:rt17_human(display_long)|uniprotkb:MRPS17(gene name)|psi-mi:MRPS17(display_short)|uniprotkb:RPMS17(gene name synonym)|uniprotkb:HSPC011(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein uS17m(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 ensembl:ENSG00000239789(gene)|ensembl:ENST00000285298(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR039193|mint:Q9Y2R5|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|reactome:R-HSA-5389840|rcsb pdb:6ZSB|reactome:R-HSA-5419276|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|refseq:NP_057053.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:UDEpLcg5pGMMYvvc72HnPf9169U9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:P82930 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-1048516|uniprotkb:Q9BVI7|ensembl:ENSP00000380531 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:rt34_human(display_long)|uniprotkb:MRPS34(gene name)|psi-mi:MRPS34(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS34(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_001287829.1|refseq:NP_076425.1|ensembl:ENSG00000074071(gene)|ensembl:ENST00000397375(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR032053|mint:P82930|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:UTZkYPSJqThFKwoB7D5sH6g0zuc9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:P54105 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-724693|uniprotkb:Q0VDK6|uniprotkb:Q9NRD2|uniprotkb:Q9NRD3|uniprotkb:B2RCS9|ensembl:ENSP00000433919|ensembl:ENSP00000434311 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:icln_human(display_long)|uniprotkb:Chloride conductance regulatory protein ICln(gene name synonym)|uniprotkb:Chloride channel, nucleotide sensitive 1A(gene name synonym)|uniprotkb:Chloride ion current inducer protein(gene name synonym)|uniprotkb:Reticulocyte pICln(gene name synonym)|uniprotkb:CLNS1A(gene name)|psi-mi:CLNS1A(display_short)|uniprotkb:ICLN(gene name synonym)|uniprotkb:CLCI(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_001284.1|refseq:NP_001298128.1|refseq:NP_001298129.1|refseq:NP_001298130.1|refseq:NP_001298131.1|ensembl:ENSG00000074201(gene)|ensembl:ENST00000525428(transcript)|ensembl:ENST00000528364(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|interpro:IPR003521(Nucleotide-sensitive chloride conductance regulator)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039924|mint:P54105|rcsb pdb:6V0O|reactome:R-HSA-191859|dip:DIP-44185N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:dGx9UwPj9VBp1CiPTRCXnT3IYt89606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:Q9Y676 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-750085|uniprotkb:Q9BS27|uniprotkb:A6NDQ0|uniprotkb:Q659G4|intact:EBI-1050511|ensembl:ENSP00000259873|ensembl:ENSP00000383438|ensembl:ENSP00000397790|ensembl:ENSP00000398494|ensembl:ENSP00000402718|ensembl:ENSP00000414972|ensembl:ENSP00000415703 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:rt18b_human(display_long)|uniprotkb:28S ribosomal protein S18-2, mitochondrial(gene name synonym)|uniprotkb:C6orf14(gene name synonym)|uniprotkb:MRPS18B(gene name)|psi-mi:MRPS18B(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein bS18b(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS40(gene name synonym)|uniprotkb:HSPC183(orf name)|uniprotkb:PTD017(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_054765.1|dip:DIP-29894N|ensembl:ENSG00000203624(gene)|ensembl:ENSG00000204568(gene)|ensembl:ENSG00000223775(gene)|ensembl:ENSG00000226111(gene)|ensembl:ENSG00000227420(gene)|ensembl:ENSG00000229861(gene)|ensembl:ENSG00000233813(gene)|ensembl:ENST00000259873(transcript)|ensembl:ENST00000327800(transcript)|ensembl:ENST00000412451(transcript)|ensembl:ENST00000426945(transcript)|ensembl:ENST00000430402(transcript)|ensembl:ENST00000451032(transcript)|ensembl:ENST00000454427(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0030054"(cell junction)|go:"GO:0032543"(mitochondrial translation)|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|interpro:IPR001648(Ribosomal protein S18)|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|interpro:IPR036870|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|interpro:IPR040054|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|mint:Q9Y676 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:DFGekxKm74bAo8IWpOi8LDITWqc9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:Q9BQA1 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-1237307|uniprotkb:B3KMW6|uniprotkb:Q96GK4|uniprotkb:Q9BWY3|uniprotkb:Q3LID2|uniprotkb:Q53FU2|uniprotkb:Q6JZZ5|uniprotkb:B4DP38|ensembl:ENSP00000235090 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:mep50_human(display_long)|uniprotkb:WDR77(gene name)|psi-mi:WDR77(display_short)|uniprotkb:MEP50(gene name synonym)|uniprotkb:WD repeat-containing protein 77(gene name synonym)|uniprotkb:Androgen receptor cofactor p44(gene name synonym)|uniprotkb:p44/Mep50(gene name synonym)|uniprotkb:HKMT1069(orf name)|uniprotkb:Nbla10071(orf name)|uniprotkb:WD45(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_077007.1|refseq:NP_001303991.1|refseq:NP_001303992.1|refseq:NP_001303993.1|dip:DIP-38172N|ensembl:ENSG00000116455(gene)|ensembl:ENST00000235090(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0034709"(methylosome)|go:"GO:0045495"(pole plasm)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9BQA1|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:0q4wunYtHalObC8r1wphhelIpr49606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:Q9NTK5 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-766468|uniprotkb:Q5BJD7|uniprotkb:Q8NCI8|uniprotkb:Q96CU1|uniprotkb:Q96SV2|uniprotkb:Q9P1D3|uniprotkb:Q9UNY9|uniprotkb:Q9Y6G4|uniprotkb:D7EHM2|ensembl:ENSP00000284719 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:ola1_human(display_long)|uniprotkb:GTPBP9(gene name synonym)|uniprotkb:GTP-binding protein 9(gene name synonym)|uniprotkb:OLA1(gene name)|psi-mi:OLA1(display_short)|uniprotkb:PTD004(orf name)|uniprotkb:PRO2455(orf name)|uniprotkb:DNA damage-regulated overexpressed in cancer 45(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_001011708.1|refseq:NP_037473.3|dip:DIP-34591N|ensembl:ENST00000284719(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004095(TGS)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR023192|interpro:IPR027417|interpro:IPR031167|interpro:IPR041706|mint:Q9NTK5|rcsb pdb:2OHF|reactome:R-HSA-114608|ensembl:ENSG00000138430(gene) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:aQk5XBcKpx1YSW4mHtyRsTpimvk9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:Q9BT78 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-742413|uniprotkb:Q561W7|uniprotkb:Q9NW31|uniprotkb:Q9Y677|uniprotkb:B3KN88|ensembl:ENSP00000264389|uniprotkb:B3KST5 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:csn4_human(display_long)|uniprotkb:COPS4(gene name)|psi-mi:COPS4(display_short)|uniprotkb:CSN4(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 4(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 ensembl:ENSG00000138663(gene)|refseq:NP_057213.2|refseq:NP_001244935.1|go:"GO:0016607"(nuclear speck)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0030054"(cell junction)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|interpro:IPR041406|mint:Q9BT78|rcsb pdb:4D0P|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-9013422|ensembl:ENST00000264389(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|refseq:NP_001317656.1|dip:DIP-34516N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:onrZiPzG+bZvycmpDTZMtkPzCfQ9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:P82675 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-1054287|uniprotkb:Q96LJ6|uniprotkb:Q9BWI4|uniprotkb:Q9BYC4|uniprotkb:Q4ZFY5|ensembl:ENSP00000272418 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:rt05_human(display_long)|uniprotkb:MRPS5(gene name)|psi-mi:MRPS5(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS5m(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_114108.1|ensembl:ENSG00000144029(gene)|ensembl:ENST00000272418(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018192|interpro:IPR020568|mint:P82675|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6RW5|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:l+aZgmDVWWimuUiH4IS4FG1cwlQ9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:P63151 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-1048931|uniprotkb:P50409|uniprotkb:Q00007|uniprotkb:B2RBU8|intact:EBI-2556013|uniprotkb:B4E1T7|ensembl:ENSP00000370113 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:2aba_human(display_long)|uniprotkb:PPP2R2A(gene name)|psi-mi:PPP2R2A(display_short)|uniprotkb:PP2A subunit B isoform alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-alpha(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_001171062.1|refseq:NP_002708.1|ensembl:ENSG00000221914(gene)|ensembl:ENST00000380737(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:P63151|rcsb pdb:3DW8|reactome:R-HSA-2995383|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-975957|dip:DIP-29398N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:evS6klM2alZXtMthVsshKkrNgiA9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:P13489 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-1237106|uniprotkb:Q8IZK8|uniprotkb:Q96FD7|uniprotkb:Q9BQ80|uniprotkb:Q9UDK6|ensembl:ENSP00000346402|ensembl:ENSP00000348515|ensembl:ENSP00000380729|ensembl:ENSP00000380738|ensembl:ENSP00000380739|ensembl:ENSP00000416589|ensembl:ENSP00000433999|ensembl:ENSP00000435594|ensembl:ENSP00000478664|ensembl:ENSP00000479004|ensembl:ENSP00000479966|ensembl:ENSP00000480036|ensembl:ENSP00000484572|ensembl:ENSP00000487753|ensembl:ENSP00000487940|ensembl:ENSP00000488734 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:rini_human(display_long)|uniprotkb:RNH1(gene name)|psi-mi:RNH1(display_short)|uniprotkb:PRI(gene name synonym)|uniprotkb:RNH(gene name synonym)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym)|uniprotkb:Placental ribonuclease inhibitor(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_002930.2|refseq:NP_976317.1|refseq:NP_976318.1|refseq:NP_976319.1|refseq:NP_976320.1|refseq:NP_976321.1|refseq:NP_976322.1|refseq:NP_976323.1|refseq:XP_011518557.1|refseq:XP_011518559.1|refseq:XP_011518560.1|refseq:XP_011518561.1|refseq:XP_011518562.1|refseq:XP_011518563.1|refseq:XP_011518564.1|refseq:XP_011518565.1|refseq:XP_016873595.1|ensembl:ENST00000619599(transcript)|ensembl:ENST00000621211(transcript)|ensembl:ENST00000632527(transcript)|ensembl:ENST00000632954(transcript)|ensembl:ENST00000633287(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR041302|mint:P13489|rcsb pdb:1A4Y|rcsb pdb:1Z7X|rcsb pdb:2BEX|rcsb pdb:2Q4G|ensembl:ENSG00000023191(gene)|ensembl:ENSG00000276230(gene)|ensembl:ENST00000354420(transcript)|ensembl:ENST00000356187(transcript)|ensembl:ENST00000397604(transcript)|ensembl:ENST00000397614(transcript)|ensembl:ENST00000397615(transcript)|ensembl:ENST00000438658(transcript)|ensembl:ENST00000533410(transcript)|ensembl:ENST00000534797(transcript)|ensembl:ENST00000612988(transcript)|ensembl:ENST00000617351(transcript)|ensembl:ENST00000618184(transcript) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:1WMWoYulk8Aj8HYhDcqnauddUFk9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:Q96GA3 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-2558389|uniprotkb:Q96JX8|ensembl:ENSP00000356548 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:ltv1_human(display_long)|uniprotkb:LTV1(gene name)|psi-mi:LTV1(display_short)|uniprotkb:C6orf93(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_116249.2|ensembl:ENSG00000135521(gene)|ensembl:ENST00000367576(transcript)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR007307(Low temperature viability protein)|mint:Q96GA3|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|reactome:R-HSA-6791226 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:Csfx8GS5hoclLY1BYki/uUKoSIM9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:Q969S3 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-2687480|ensembl:ENSP00000310042 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:zn622_human(display_long)|uniprotkb:ZPR9(gene name synonym)|uniprotkb:Zinc finger-like protein 9(gene name synonym)|uniprotkb:ZNF622(gene name)|psi-mi:ZNF622(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_219482.1|ensembl:ENSG00000173545(gene)|ensembl:ENST00000308683(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022755|interpro:IPR036236|interpro:IPR040025|interpro:IPR041661|mint:Q969S3|rcsb pdb:6LQM|rcsb pdb:6LSR - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:WUzJA1E/Gz78ud7PgHYxKxUSvU49606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:Q9Y5Q8 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-1045409|uniprotkb:Q8N2U7|uniprotkb:Q8N857|uniprotkb:Q96GD9|uniprotkb:Q9H4P2|uniprotkb:A6NI44|uniprotkb:A6NJB9|uniprotkb:Q5T7U2|uniprotkb:Q5T7U3|intact:EBI-2556713|ensembl:ENSP00000361169 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:tf3c5_human(display_long)|uniprotkb:Transcription factor IIIC subunit epsilon(gene name synonym)|uniprotkb:TF3C-epsilon(gene name synonym)|uniprotkb:Transcription factor IIIC 63 kDa subunit(gene name synonym)|uniprotkb:GTF3C5(gene name)|psi-mi:GTF3C5(display_short)|uniprotkb:CDABP0017(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_001116295.1|refseq:NP_036219.2|ensembl:ENSG00000148308(gene)|ensembl:ENST00000372097(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR019136|interpro:IPR040454|interpro:IPR041499|interpro:IPR042536|mint:Q9Y5Q8|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|refseq:NP_001273638.1|dip:DIP-50823N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:Cb1wPs3qn4+Up/g7WgOMDEFtp+M9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:O15355 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-725702|ensembl:ENSP00000342778 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:ppm1g_human(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:PPM1G(gene name)|psi-mi:PPM1G(display_short)|uniprotkb:PPM1C(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_817092.1|ensembl:ENST00000344034(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|ensembl:ENSG00000115241(gene)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:O15355|dip:DIP-29404N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:j9ut2f7QHVyOtsLuYJ8e2XOP3HE9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:Q96EY7 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-721110|uniprotkb:A6NHD2|uniprotkb:Q597H0|uniprotkb:Q658Y9|uniprotkb:Q9BUZ8|uniprotkb:Q9NWL0|intact:EBI-2560120|uniprotkb:D6W5M1|ensembl:ENSP00000254630 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:ptcd3_human(display_long)|uniprotkb:Transformation-related gene 15 protein(gene name synonym)|uniprotkb:TRG15(orf name)|uniprotkb:28S ribosomal protein S39, mitochondrial(gene name synonym)|uniprotkb:MRPS39(gene name synonym)|uniprotkb:PTCD3(gene name)|psi-mi:PTCD3(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS39(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_060422.4|go:"GO:0032543"(mitochondrial translation)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR037387|mint:Q96EY7|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|go:"GO:0019843"(rRNA binding)|rcsb pdb:6ZSC|ensembl:ENSG00000132300(gene)|ensembl:ENST00000254630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZSD - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:k9hyBtBrNbiBMJ5gtOQ9R6Grl9U9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:Q14566 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-374900|uniprotkb:Q13504|uniprotkb:Q99859|uniprotkb:B2R6H2|ensembl:ENSP00000264156 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:mcm6_human(display_long)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:p105MCM(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 ensembl:ENST00000264156(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|ensembl:ENSG00000076003(gene)|reactome:R-HSA-68962|reactome:R-HSA-69052|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|interpro:IPR001208(MCM)|mint:Q14566|rcsb pdb:2KLQ|rcsb pdb:2LE8|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|refseq:NP_005906.2|dip:DIP-31727N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:gVpEwgfSwwxvP2T2CvCzIukthY49606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:Q5H9R7 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-355498|uniprotkb:Q3B7I1|uniprotkb:Q7L4R8|uniprotkb:Q8N3B2|uniprotkb:Q96MB2|uniprotkb:Q9H2K5|uniprotkb:Q9H2K6|uniprotkb:Q9HCL4|uniprotkb:Q9NUY3|uniprotkb:Q3I4Y0|uniprotkb:Q3KR35|uniprotkb:Q68CR3|intact:EBI-28971860|ensembl:ENSP00000377389 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:pp6r3_human(display_long)|uniprotkb:PPP6R3(gene name)|psi-mi:PPP6R3(display_short)|uniprotkb:C11orf23(gene name synonym)|uniprotkb:KIAA1558(gene name synonym)|uniprotkb:PP6R3(gene name synonym)|uniprotkb:SAPL(gene name synonym)|uniprotkb:Sporulation-induced transcript 4-associated protein SAPL(gene name synonym)|uniprotkb:SAPS domain family member 3(gene name synonym)|uniprotkb:SAPS3(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_001157632.1|refseq:NP_001157633.1|refseq:NP_001157634.1|refseq:NP_001157635.1|refseq:NP_001157636.1|refseq:NP_060782.2|ensembl:ENST00000265636|ensembl:ENSP00000265636|ensembl:ENSP00000377389|ensembl:ENST00000393801|ensembl:ENSP00000377390|ensembl:ENST00000524845|ensembl:ENSP00000431415|ensembl:ENST00000524904|ensembl:ENSP00000433058|ensembl:ENST00000529710|ensembl:ENSP00000437329|refseq:XP_011543442.1|refseq:XP_006718676.1|refseq:XP_006718677.1|refseq:XP_006718681.1|refseq:XP_006718687.1|refseq:XP_016873451.1|refseq:XP_016873452.1|refseq:XP_016873455.1|ensembl:ENSG00000110075(gene)|ensembl:ENST00000393800(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q5H9R7|reactome:R-HSA-171319|reactome:R-HSA-204005 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:9hU14AmzYI9nORfchfMtLoyRecA9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:Q8TEX9 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-395967|uniprotkb:Q2NL96|uniprotkb:Q86TZ9|uniprotkb:Q8NCG8|uniprotkb:Q96SJ3|uniprotkb:Q9BTI4|uniprotkb:Q9H5L0|uniprotkb:B2RN95|ensembl:ENSP00000346453|ensembl:ENSP00000494795 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:ipo4_human(display_long)|uniprotkb:IPO4(gene name)|psi-mi:IPO4(display_short)|uniprotkb:IMP4B(gene name synonym)|uniprotkb:RANBP4(gene name synonym)|uniprotkb:Importin-4b(gene name synonym)|uniprotkb:Ran-binding protein 4(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_078934.3|dip:DIP-32944N|ensembl:ENSG00000196497(gene)|ensembl:ENSG00000285248(gene)|ensembl:ENST00000354464(transcript)|ensembl:ENST00000644546(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|interpro:IPR040122|mint:Q8TEX9|rcsb pdb:5XAH|rcsb pdb:5XBK - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:PVIcGG3WTf0QmYbS0vvy049EjlQ9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:O00410 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-356424|uniprotkb:O15257|intact:EBI-1105173|uniprotkb:B4DZA0|uniprotkb:Q5T578|uniprotkb:Q86XC7|ensembl:ENSP00000350219|ensembl:ENSP00000418393|ensembl:ENSP00000499125 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:ipo5_human(display_long)|uniprotkb:IPO5(gene name)|psi-mi:IPO5(display_short)|uniprotkb:KPNB3(gene name synonym)|uniprotkb:RANBP5(gene name synonym)|uniprotkb:Importin subunit beta-3(gene name synonym)|uniprotkb:Karyopherin beta-3(gene name synonym)|uniprotkb:Ran-binding protein 5(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_002262.3|refseq:XP_011519389.1|refseq:XP_011519390.1|refseq:XP_011519391.1|refseq:XP_011519392.1|ensembl:ENSG00000065150(gene)|ensembl:ENST00000357602(transcript)|ensembl:ENST00000490680(transcript)|ensembl:ENST00000651721(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|refseq:XP_005254109.1|refseq:XP_005254110.1|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR034085|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653|mint:O00410|rcsb pdb:6XTE|rcsb pdb:6XU2|reactome:R-HSA-192905|refseq:XP_016876051.1|dip:DIP-41042N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:jBYLvkqyYyWAu1TdCVyCMh9ZHKY9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:Q9Y4B6 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-1996353|uniprotkb:Q2YD74|uniprotkb:Q8TBD9|uniprotkb:Q9HCA1|uniprotkb:Q9UG37|intact:EBI-2559078|intact:EBI-28988191|ensembl:ENSP00000393183|ensembl:ENSP00000506880 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:dcaf1_human(display_long)|uniprotkb:DCAF1(gene name)|psi-mi:DCAF1(display_short)|uniprotkb:HIV-1 Vpr-binding protein(gene name synonym)|uniprotkb:KIAA0800(gene name synonym)|uniprotkb:RIP(gene name synonym)|uniprotkb:Serine/threonine-protein kinase VPRBP(gene name synonym)|uniprotkb:VPRBP(gene name synonym)|uniprotkb:Vpr-interacting protein(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_001165375.1|refseq:NP_055518.1|refseq:XP_011532575.1|refseq:XP_011532576.1|refseq:XP_011532577.1|refseq:XP_011532578.1|refseq:XP_011532579.1|refseq:XP_016863035.1|refseq:XP_016863036.1|refseq:XP_016863037.1|refseq:XP_016863038.1|refseq:XP_016863039.1|ensembl:ENST00000335891|ensembl:ENSP00000338857|ensembl:ENSP00000393183|ensembl:ENST00000504652|ensembl:ENSP00000421724|ensembl:ENSP00000506880|ensembl:ENSG00000145041(gene)|ensembl:ENST00000423656(transcript)|ensembl:ENST00000684031(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990244"("histone kinase activity (H2A-T120 specific)")|go:"GO:1990245"(histone H2A-T120 phosphorylation)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033270|interpro:IPR036322|mint:Q9Y4B6|rcsb pdb:3WA0|rcsb pdb:4CC9|rcsb pdb:4P7I|rcsb pdb:4PXW|rcsb pdb:4Z8L|rcsb pdb:5AJA|rcsb pdb:5JK7|rcsb pdb:6N45|reactome:R-HSA-983168|refseq:XP_005276810.1|refseq:XP_005276812.1|dip:DIP-47048N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:qs3qG0MM135EE/DjC1S/gCLRFhc9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:Q9Y4Y9 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-373007|ensembl:ENSP00000410758 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:lsm5_human(display_long)|uniprotkb:LSM5(gene name)|psi-mi:LSM5(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_001124182.1|refseq:NP_001132971.1|refseq:NP_036454.1|dip:DIP-31162N|ensembl:ENSG00000106355(gene)|ensembl:ENST00000450169(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0009617"(response to bacterium)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR033871|mint:Q9Y4Y9|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:EeF2r4qY+BFrZTyTCT+i4ccskf49606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:Q8N4Q1 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-2562213|uniprotkb:A8K3Z9|uniprotkb:Q96AI2|uniprotkb:Q96MY6|ensembl:ENSP00000380122 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:mia40_human(display_long)|uniprotkb:MIA40(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 4(gene name synonym)|uniprotkb:CHCHD4(gene name)|psi-mi:CHCHD4(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_001091972.1|refseq:NP_653237.1|ensembl:ENSG00000163528(gene)|ensembl:ENST00000396914(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0051084"('de novo' posttranslational protein folding)|interpro:IPR010625(CHCH)|interpro:IPR039289|mint:Q8N4Q1|rcsb pdb:2K3J|rcsb pdb:2L0Y|reactome:R-HSA-1268020|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|dip:DIP-48483N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:ACH8CTQRjTwq7nz6toGTrn3VHlE9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:P82650 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-1050752|ensembl:ENSP00000418008|ensembl:ENSP00000505414|uniprotkb:Q9H3I1 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:rt22_human(display_long)|uniprotkb:MRPS22(gene name)|psi-mi:MRPS22(display_short)|uniprotkb:C3orf5(gene name synonym)|uniprotkb:RPMS22(gene name synonym)|uniprotkb:GK002(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein mS22(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_064576.1|ensembl:ENSG00000175110(gene)|ensembl:ENST00000495075(transcript)|ensembl:ENST00000680020(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|interpro:IPR019374|mint:P82650|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:T0htF4/rvOZUZ3RcuCjWvEg9iTE9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:P51398 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-355912|uniprotkb:Q13044|uniprotkb:Q96Q20|uniprotkb:Q68CT7|uniprotkb:B4DP59|uniprotkb:E7EM60|uniprotkb:B4DY62|ensembl:ENSP00000341692|ensembl:ENSP00000357320 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:rt29_human(display_long)|uniprotkb:DAP3(gene name)|psi-mi:DAP3(display_short)|uniprotkb:MRPS29(gene name synonym)|uniprotkb:Death-associated protein 3(gene name synonym)|uniprotkb:Ionizing radiation resistance conferring protein(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS29(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_001186778.1|refseq:NP_004623.1|refseq:NP_387506.1|refseq:NP_001186779.1|refseq:NP_001186780.1|refseq:XP_005245537.1|refseq:XP_005245538.1|ensembl:ENSG00000132676(gene)|ensembl:ENST00000343043(transcript)|ensembl:ENST00000368336(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR008092(Death associated protein 3)|interpro:IPR019368|interpro:IPR027417|mint:P51398|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:XP_016857780.1|refseq:XP_016857781.1|refseq:XP_016857782.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:xSIyqKH4F49Iu+AVuVThJWsi9EA9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:Q66LE6 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:Q5T447 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-2691157|uniprotkb:B3KPV7|uniprotkb:B3KRH4|uniprotkb:Q5T448|uniprotkb:Q9H783|ensembl:ENSP00000361245 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:hecd3_human(display_long)|uniprotkb:HECT domain-containing protein 3(gene name synonym)|uniprotkb:HECTD3(gene name)|psi-mi:HECTD3(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase HECTD3(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_078878.3|ensembl:ENSG00000126107(gene)|ensembl:ENST00000372172(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000569(HECT)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR035983|interpro:IPR042469|mint:Q5T447|reactome:R-HSA-983168|go:"GO:0019905"(syntaxin binding) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:laodrF8CReKmM4d6n3sHGBmQB6Q9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:P14735 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-2556886|uniprotkb:Q5T5N2|uniprotkb:D3DR35|ensembl:ENSP00000265986|uniprotkb:B2R721|uniprotkb:B7ZAU2 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:ide_human(display_long)|uniprotkb:IDE(gene name)|psi-mi:IDE(display_short)|uniprotkb:Insulin protease(gene name synonym)|uniprotkb:Insulysin(gene name synonym)|uniprotkb:Abeta-degrading protease(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_004960.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010815"(bradykinin catabolic process)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031626"(beta-endorphin binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042447"(hormone catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000119912(gene)|ensembl:ENST00000265986(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001618"(virus receptor activity)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0043559"(insulin binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0140036"(ubiquitin-dependent protein binding)|go:"GO:0150094"(amyloid-beta clearance by cellular catabolic process)|go:"GO:1901142"(insulin metabolic process)|go:"GO:1901143"(insulin catabolic process)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR032632|mint:P14735|rcsb pdb:2G47|rcsb pdb:2G48|rcsb pdb:2G49|rcsb pdb:2G54|rcsb pdb:2G56|rcsb pdb:2JBU|rcsb pdb:2JG4|rcsb pdb:2WBY|rcsb pdb:2WC0|rcsb pdb:2WK3|rcsb pdb:2YPU|rcsb pdb:3CWW|rcsb pdb:3E4A|rcsb pdb:3E4Z|rcsb pdb:3E50|rcsb pdb:3H44|rcsb pdb:3N56|rcsb pdb:3N57|rcsb pdb:3OFI|rcsb pdb:3QZ2|rcsb pdb:4DTT|rcsb pdb:4DWK|rcsb pdb:4GS8|rcsb pdb:4GSC|rcsb pdb:4GSF|rcsb pdb:4IFH|rcsb pdb:4IOF|rcsb pdb:4LTE|rcsb pdb:4M1C|rcsb pdb:4NXO|rcsb pdb:4PES|rcsb pdb:4PF7|rcsb pdb:4PF9|rcsb pdb:4PFC|rcsb pdb:4QIA|rcsb pdb:4RAL|rcsb pdb:4RE9|rcsb pdb:5CJO|rcsb pdb:3HGZ|rcsb pdb:5UOE|rcsb pdb:5WOB|rcsb pdb:6B3Q|rcsb pdb:6B70|rcsb pdb:6B7Y|rcsb pdb:6BF6|rcsb pdb:6BF7|rcsb pdb:6BF8|rcsb pdb:6BF9|rcsb pdb:6BFC|rcsb pdb:6BYZ|rcsb pdb:6EDS|rcsb pdb:6MQ3|reactome:R-HSA-5689880|reactome:R-HSA-9033241|rcsb pdb:6B7Z|refseq:NP_001159418.1|dip:DIP-55771N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:dwngN3kUOExC5qapSgF01YhBNAM9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:Q9C0C9 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-2339946|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q9H6E6|ensembl:ENSP00000323687 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_071349.3|ensembl:ENSG00000175931(gene)|ensembl:ENST00000319380(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|reactome:R-HSA-983168 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:Q9BZ29 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-2695893|uniprotkb:Q5TAN8|uniprotkb:Q9BZ25|uniprotkb:Q9BZ26|uniprotkb:Q5T2Q1|uniprotkb:Q5JUD6|uniprotkb:Q5JUD4|uniprotkb:Q9BZ27|uniprotkb:Q9BZ28|uniprotkb:Q9UPU4|uniprotkb:B3KX25|uniprotkb:E9PFM9|ensembl:ENSP00000498761 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:dock9_human(display_long)|uniprotkb:Cdc42 guanine nucleotide exchange factor zizimin-1(gene name synonym)|uniprotkb:KIAA1058(gene name synonym)|uniprotkb:DOCK9(gene name)|psi-mi:DOCK9(display_short)|uniprotkb:ZIZ1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_001305778.1|refseq:NP_001123520.1|refseq:NP_001123521.1|refseq:NP_001123522.1|refseq:NP_056111.1|ensembl:ENSG00000088387(gene)|ensembl:ENST00000652315(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR026796|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037809|interpro:IPR043161|interpro:IPR043162|mint:Q9BZ29|rcsb pdb:1WG7|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:0uqFLEeF0UV1x4KlrfoX0pEdj7g9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84388 uniprotkb:O43149 intact:EBI-22302849|ensemblbacteria:AAC67979 intact:EBI-715672|uniprotkb:Q6NXG0|uniprotkb:Q6ZRA1|uniprotkb:Q6ZSF4|uniprotkb:Q9NVB9|uniprotkb:A7MBM5|ensembl:ENSP00000371051 psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name) psi-mi:zzef1_human(display_long)|uniprotkb:ZZEF1(gene name)|psi-mi:ZZEF1(display_short)|uniprotkb:KIAA0399(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302856|imex:IM-27647-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67979(transcript)|ensemblbacteria:CT_383(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84388|refseq:NP_219893.1|refseq:WP_009871735.1 refseq:NP_055928.3|go:"GO:0005509"(calcium ion binding)|go:"GO:0008270"(zinc ion binding)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011992(EF-Hand type)|interpro:IPR040099|interpro:IPR041986|interpro:IPR043145|mint:O43149|ensembl:ENST00000381638(transcript)|ensembl:ENSG00000074755(gene) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561 rogid:LpYXMInET7VBZ/ZLV23wuQksKTA9606 rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s false binding-associated region:156-243|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84560 uniprotkb:O75431 intact:EBI-22302898|ensemblbacteria:AAC68158 intact:EBI-7415268|uniprotkb:Q53SQ2|uniprotkb:Q5M7Z6|uniprotkb:A8JZZ4|intact:MINT-3001232|intact:MINT-4876050|uniprotkb:Q53S50|ensembl:ENSP00000249442|uniprotkb:Q8IZ68 psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name) psi-mi:mtx2_human(display_long)|uniprotkb:MTX2(gene name)|psi-mi:MTX2(display_short)|uniprotkb:Mitochondrial outer membrane import complex protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302905|imex:IM-27647-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68158(transcript)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_556(gene)|mint:O84560|refseq:WP_009872749.1|refseq:NP_220071.1 refseq:NP_001306026.1|refseq:NP_001306027.1|refseq:NP_001006636.1|refseq:NP_006545.1|ensembl:ENSG00000128654(gene)|ensembl:ENST00000249442(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0015031"(protein transport)|interpro:IPR019564|interpro:IPR033468|interpro:IPR036282|interpro:IPR040079|mint:O75431|reactome:R-HSA-1268020|reactome:R-HSA-8949613|go:"GO:0140275"(MIB complex) - - comment:mint|function:Involved in transport of proteins into the mitochondrion figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561 rogid:M4zfGX8gfFUFW7xYoXeEzA2UCSM9606 rigid:ej5JnwVBem7Q1WbACmSX4AaZkrY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84560 uniprotkb:Q9BVC4 intact:EBI-22302898|ensemblbacteria:AAC68158 intact:EBI-1387471|intact:EBI-1567843|uniprotkb:Q5M800|uniprotkb:Q86Y18|uniprotkb:Q8WUI5|uniprotkb:Q9HA66|uniprotkb:Q9UJV6|uniprotkb:B4DY00|uniprotkb:B3KMM4|uniprotkb:D3DU88|ensembl:ENSP00000380313|ensembl:ENSP00000455046|ensembl:ENSP00000456405|ensembl:ENSP00000457870 psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name) psi-mi:lst8_human(display_long)|uniprotkb:MLST8(gene name)|psi-mi:MLST8(display_short)|uniprotkb:GBL(gene name synonym)|uniprotkb:G protein beta subunit-like(gene name synonym)|uniprotkb:LST8(gene name synonym)|uniprotkb:Mammalian lethal with SEC13 protein 8(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302905|imex:IM-27647-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68158(transcript)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_556(gene)|mint:O84560|refseq:WP_009872749.1|refseq:NP_220071.1 refseq:NP_001186102.1|refseq:NP_001186103.1|refseq:NP_001186104.1|refseq:NP_071767.3|refseq:XP_016879037.1|refseq:XP_016879038.1|dip:DIP-39481N|ensembl:ENSG00000167965(gene)|ensembl:ENST00000397124(transcript)|ensembl:ENST00000564088(transcript)|ensembl:ENST00000565250(transcript)|ensembl:ENST00000569417(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR037588|mint:Q9BVC4|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5H64|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:6BCX|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561 rogid:BQek96xYe/1IaE8vgX3Uvl9vkCc9606 rigid:ej5JnwVBem7Q1WbACmSX4AaZkrY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84560 uniprotkb:Q96D46 intact:EBI-22302898|ensemblbacteria:AAC68158 intact:EBI-2371176|uniprotkb:Q9Y2Z6|uniprotkb:D3DNM7|ensembl:ENSP00000307525|ensembl:ENSP00000419004 psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name) psi-mi:nmd3_human(display_long)|uniprotkb:NMD3(gene name)|psi-mi:NMD3(display_short)|uniprotkb:CGI-07(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302905|imex:IM-27647-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68158(transcript)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_556(gene)|mint:O84560|refseq:WP_009872749.1|refseq:NP_220071.1 refseq:NP_057022.2|refseq:XP_005247568.1|refseq:XP_005247569.1|dip:DIP-53427N|ensembl:ENSG00000169251(gene)|ensembl:ENST00000351193(transcript)|ensembl:ENST00000460469(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:1902680"(positive regulation of RNA biosynthetic process)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR007064(NMD3)|interpro:IPR039768|mint:Q96D46|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LU8 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561 rogid:ufeZYizNnQTOnJjgF+zmyLQphJE9606 rigid:ej5JnwVBem7Q1WbACmSX4AaZkrY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84560 uniprotkb:P49915 intact:EBI-22302898|ensemblbacteria:AAC68158 intact:EBI-1050289|uniprotkb:A8K639|uniprotkb:B4DXV7|uniprotkb:F8W720|ensembl:ENSP00000419851 psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name) psi-mi:guaa_human(display_long)|uniprotkb:GMP synthetase(gene name synonym)|uniprotkb:Glutamine amidotransferase(gene name synonym)|uniprotkb:GMPS(gene name)|psi-mi:GMPS(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302905|imex:IM-27647-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68158(transcript)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_556(gene)|mint:O84560|refseq:WP_009872749.1|refseq:NP_220071.1 refseq:NP_003866.1|ensembl:ENSG00000163655(gene)|ensembl:ENST00000496455(transcript)|go:"GO:0003921"(GMP synthase activity)|go:"GO:0003922"("GMP synthase (glutamine-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0009168"(purine ribonucleoside monophosphate biosynthetic process)|go:"GO:0016462"(pyrophosphatase activity)|interpro:IPR001674(GMP synthase, C-terminal)|interpro:IPR004739(GMP synthase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR017926|interpro:IPR022310|interpro:IPR025777|interpro:IPR029062|mint:P49915|rcsb pdb:2VPI|rcsb pdb:2VXO|reactome:R-HSA-73817 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561 rogid:LYs65bPoqjVG/ZxA6v+yJo3HsLI9606 rigid:ej5JnwVBem7Q1WbACmSX4AaZkrY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84560 uniprotkb:P38435 intact:EBI-22302898|ensemblbacteria:AAC68158 intact:EBI-10963113|ensembl:ENSP00000233838|uniprotkb:B4DMC5|uniprotkb:E9PEE1|uniprotkb:Q6GU45|uniprotkb:Q14415 psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name) psi-mi:vkgc_human(display_long)|uniprotkb:GGCX(gene name)|psi-mi:GGCX(display_short)|uniprotkb:GC(gene name synonym)|uniprotkb:Gamma-glutamyl carboxylase(gene name synonym)|uniprotkb:Peptidyl-glutamate 4-carboxylase(gene name synonym)|uniprotkb:Vitamin K gamma glutamyl carboxylase(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302905|imex:IM-27647-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68158(transcript)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_556(gene)|mint:O84560|refseq:WP_009872749.1|refseq:NP_220071.1 refseq:NP_000812.2|refseq:NP_001135741.1|ensembl:ENSG00000115486(gene)|ensembl:ENST00000233838(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007596"(blood coagulation)|go:"GO:0008488"(gamma-glutamyl carboxylase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017187"(peptidyl-glutamic acid carboxylation)|go:"GO:0019842"(vitamin binding)|interpro:IPR007782(Vitamin K-dependent gamma-carboxylase)|interpro:IPR011020(HTTM)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|mint:P38435|reactome:R-HSA-159740|reactome:R-HSA-9673240 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561 rogid:icDLv1KyH9HC3h9enCp9S/nXPmM9606 rigid:ej5JnwVBem7Q1WbACmSX4AaZkrY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84560 uniprotkb:P84077 intact:EBI-22302898|ensemblbacteria:AAC68158 intact:EBI-447171|uniprotkb:P10947|uniprotkb:P32889|ensembl:ENSP00000272102|ensembl:ENSP00000440005|ensembl:ENSP00000442980 psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name) psi-mi:arf1_human(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302905|imex:IM-27647-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68158(transcript)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_556(gene)|mint:O84560|refseq:WP_009872749.1|refseq:NP_220071.1 refseq:NP_001019397.1|refseq:NP_001019398.1|refseq:NP_001019399.1|refseq:NP_001649.1|dip:DIP-31597N|ensembl:ENSG00000143761(gene)|ensembl:ENST00000272102(transcript)|ensembl:ENST00000540651(transcript)|ensembl:ENST00000541182(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043005"(neuron projection)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055108"(Golgi to transport vesicle transport)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070142"(synaptic vesicle budding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:1903725"(regulation of phospholipid metabolic process)|go:"GO:1990386"(mitotic cleavage furrow ingression)|go:"GO:1990583"(phospholipase D activator activity)|interpro:IPR005225(Small GTP-binding protein)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P84077|rcsb pdb:1HUR|rcsb pdb:1RE0|rcsb pdb:1U81|rcsb pdb:3O47|rcsb pdb:4HMY|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:6FAE|rcsb pdb:7MGE|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-167590|reactome:R-HSA-199992|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-8950505 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561 rogid:zray9asm6VonxpuJpv0dRBspPt89606 rigid:ej5JnwVBem7Q1WbACmSX4AaZkrY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84560 uniprotkb:Q9P0L0 intact:EBI-22302898|ensemblbacteria:AAC68158 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name) psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302905|imex:IM-27647-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68158(transcript)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_556(gene)|mint:O84560|refseq:WP_009872749.1|refseq:NP_220071.1 refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 rigid:ej5JnwVBem7Q1WbACmSX4AaZkrY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84560 uniprotkb:Q9H3G5 intact:EBI-22302898|ensemblbacteria:AAC68158 intact:EBI-357542|uniprotkb:Q6UX20|uniprotkb:Q8NBL7|uniprotkb:Q96AR7|uniprotkb:Q9HB41|ensembl:ENSP00000265394|ensembl:ENSP00000379572|ensembl:ENSP00000387164|intact:EBI-1058665|uniprotkb:A4D1A4 psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name) psi-mi:cpvl_human(display_long)|uniprotkb:CPVL(gene name)|psi-mi:CPVL(display_short)|uniprotkb:VLP(gene name synonym)|uniprotkb:UNQ197/PRO223(orf name)|uniprotkb:PSEC0124(orf name)|uniprotkb:Carboxypeptidase, vitellogenic-like(gene name synonym)|uniprotkb:Vitellogenic carboxypeptidase-like protein(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302905|imex:IM-27647-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68158(transcript)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_556(gene)|mint:O84560|refseq:WP_009872749.1|refseq:NP_220071.1 ensembl:ENSG00000106066(gene)|ensembl:ENST00000265394(transcript)|ensembl:ENST00000396276(transcript)|ensembl:ENST00000409850(transcript)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|mint:Q9H3G5|refseq:NP_061902.2|refseq:NP_112601.3|refseq:XP_011513739.1|refseq:NP_001334981.1|refseq:NP_001334983.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561 rogid:antgab61u6D+KmbopQeowXqSqWQ9606 rigid:ej5JnwVBem7Q1WbACmSX4AaZkrY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84560 uniprotkb:Q9NVH1 intact:EBI-22302898|ensemblbacteria:AAC68158 intact:EBI-1055336|uniprotkb:Q4VWF5|uniprotkb:Q5VZN0|uniprotkb:Q6PK20|uniprotkb:Q6PK70|uniprotkb:Q8NDM2|uniprotkb:Q96CL7|ensembl:ENSP00000366800 psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name) psi-mi:djc11_human(display_long)|uniprotkb:DNAJC11(gene name)|psi-mi:DNAJC11(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302905|imex:IM-27647-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68158(transcript)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_556(gene)|mint:O84560|refseq:WP_009872749.1|refseq:NP_220071.1 refseq:NP_060668.2|ensembl:ENSG00000007923(gene)|ensembl:ENST00000377577(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016607"(nuclear speck)|go:"GO:0042407"(cristae formation)|go:"GO:0140275"(MIB complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR024586|interpro:IPR036869|mint:Q9NVH1|reactome:R-HSA-8949613 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561 rogid:+I9CW/QUSn5NIkn2CRTFzq50c/I9606 rigid:ej5JnwVBem7Q1WbACmSX4AaZkrY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84560 uniprotkb:Q8N0U8 intact:EBI-22302898|ensemblbacteria:AAC68158 intact:EBI-11337915|uniprotkb:E7ETM5|uniprotkb:Q6AHW9|uniprotkb:B4E222|uniprotkb:Q6TEK6|ensembl:ENSP00000353998|ensembl:ENSP00000497394 psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name) psi-mi:vkorl_human(display_long)|uniprotkb:VKORC1L1(gene name)|psi-mi:VKORC1L1(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302905|imex:IM-27647-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68158(transcript)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_556(gene)|mint:O84560|refseq:WP_009872749.1|refseq:NP_220071.1 refseq:NP_001271271.1|refseq:NP_775788.2|ensembl:ENSG00000196715(gene)|ensembl:ENST00000360768(transcript)|ensembl:ENST00000648179(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017187"(peptidyl-glutamic acid carboxylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042373"(vitamin K metabolic process)|go:"GO:0047057"("vitamin-K-epoxide reductase (warfarin-sensitive) activity")|go:"GO:0048038"(quinone binding)|interpro:IPR012932(Vitamin K epoxide reductase)|interpro:IPR038354|interpro:IPR042406|mint:Q8N0U8|reactome:R-HSA-6806664 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561 rogid:0gdoyZTMoqEjTsPOfeUNSlH4M7k9606 rigid:ej5JnwVBem7Q1WbACmSX4AaZkrY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84560 uniprotkb:P62491 intact:EBI-22302898|ensemblbacteria:AAC68158 intact:EBI-745098|uniprotkb:P24410|uniprotkb:Q5TZN9|uniprotkb:Q9JLX1|ensembl:ENSP00000261890|uniprotkb:B2R4B6|uniprotkb:B4DT13 psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name) psi-mi:rb11a_human(display_long)|uniprotkb:YL8(gene name synonym)|uniprotkb:RAB11A(gene name)|psi-mi:RAB11A(display_short)|uniprotkb:RAB11(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302905|imex:IM-27647-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68158(transcript)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_556(gene)|mint:O84560|refseq:WP_009872749.1|refseq:NP_220071.1 ensembl:ENSG00000103769(gene)|ensembl:ENST00000261890(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|refseq:NP_001193765.1|refseq:NP_004654.1|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62491|rcsb pdb:1OIV|rcsb pdb:1OIW|rcsb pdb:1OIX|rcsb pdb:1YZK|rcsb pdb:2D7C|rcsb pdb:2GZD|rcsb pdb:2GZH|rcsb pdb:2HV8|rcsb pdb:4C4P|rcsb pdb:4D0L|rcsb pdb:4D0M|rcsb pdb:4LWZ|rcsb pdb:4LX0|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:5C46|rcsb pdb:5C4G|rcsb pdb:5EUQ|rcsb pdb:5EZ5|rcsb pdb:5FBL|rcsb pdb:5FBQ|rcsb pdb:5FBR|rcsb pdb:5FBV|rcsb pdb:5FBW|rcsb pdb:5JCZ|rcsb pdb:6DJL|rcsb pdb:6IXV|reactome:R-HSA-1445148|reactome:R-HSA-432040|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|go:"GO:0019905"(syntaxin binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0030424"(axon)|dip:DIP-29138N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561 rogid:FjkzGzN2VDTyv94M9vD/EJC2qoU9606 rigid:ej5JnwVBem7Q1WbACmSX4AaZkrY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84560 uniprotkb:O43759 intact:EBI-22302898|ensemblbacteria:AAC68158 intact:EBI-6269521|ensembl:ENSP00000332287|uniprotkb:A6NP69|uniprotkb:A8K0E2|uniprotkb:O43757|uniprotkb:O43758|uniprotkb:Q53Y02|uniprotkb:Q96J56|uniprotkb:Q9UGZ4 psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name) psi-mi:sng1_human(display_long)|uniprotkb:SYNGR1(gene name)|psi-mi:SYNGR1(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302905|imex:IM-27647-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68158(transcript)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_556(gene)|mint:O84560|refseq:WP_009872749.1|refseq:NP_220071.1 ensembl:ENSG00000100321(gene)|ensembl:ENST00000328933(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042470"(melanosome)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR008253(Marvel)|interpro:IPR016579(Synaptogyrin)|mint:O43759|reactome:R-HSA-6798695|refseq:NP_004702.2|refseq:NP_663783.1|refseq:NP_663791.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561 rogid:1wEiG09j29FhN8v7ZGSOvuK2Ong9606 rigid:ej5JnwVBem7Q1WbACmSX4AaZkrY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84560 uniprotkb:Q8NBN7 intact:EBI-22302898|ensemblbacteria:AAC68158 intact:EBI-3922765|uniprotkb:Q96G88|uniprotkb:Q6UX79|ensembl:ENSP00000391121|ensembl:ENSP00000477512 psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name) psi-mi:rdh13_human(display_long)|uniprotkb:RDH13(gene name)|psi-mi:RDH13(display_short)|uniprotkb:SDR7C3(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 7C member 3(gene name synonym)|uniprotkb:PSEC0082(orf name)|uniprotkb:UNQ736/PRO1430(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302905|imex:IM-27647-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68158(transcript)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_556(gene)|mint:O84560|refseq:WP_009872749.1|refseq:NP_220071.1 refseq:XP_011524709.1|refseq:NP_001139443.1|refseq:NP_612421.1|ensembl:ENSG00000160439(gene)|ensembl:ENST00000615256(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0009644"(response to high light intensity)|go:"GO:0010842"(retina layer formation)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042574"(retinal metabolic process)|go:"GO:0052650"(NADP-retinol dehydrogenase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q8NBN7|reactome:R-HSA-5365859|ensembl:ENSG00000276684(gene)|ensembl:ENST00000415061(transcript)|refseq:XP_005258530.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561 rogid:UHfrKddjwiPXJ6xohB99Ua0jGZo9606 rigid:ej5JnwVBem7Q1WbACmSX4AaZkrY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84560 uniprotkb:Q01581 intact:EBI-22302898|ensemblbacteria:AAC68158 intact:EBI-1055448|uniprotkb:B2RDL8|ensembl:ENSP00000322706|ensembl:ENSP00000399402 psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name) psi-mi:hmcs1_human(display_long)|uniprotkb:3-hydroxy-3-methylglutaryl coenzyme A synthase(gene name synonym)|uniprotkb:HMGCS1(gene name)|psi-mi:HMGCS1(display_short)|uniprotkb:HMGCS(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302905|imex:IM-27647-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68158(transcript)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_556(gene)|mint:O84560|refseq:WP_009872749.1|refseq:NP_220071.1 refseq:NP_001311148.1|refseq:NP_001311149.1|refseq:NP_001311151.1|refseq:NP_001311152.1|refseq:NP_001311153.1|refseq:NP_001091742.1|refseq:NP_002121.4|ensembl:ENSG00000112972(gene)|ensembl:ENST00000325110(transcript)|ensembl:ENST00000433297(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004421"(hydroxymethylglutaryl-CoA synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0009645"(response to low light intensity stimulus)|go:"GO:0010142"(farnesyl diphosphate biosynthetic process, mevalonate pathway)|go:"GO:0014074"(response to purine-containing compound)|go:"GO:0016853"(isomerase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0033197"(response to vitamin E)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043177"(organic acid binding)|go:"GO:0046690"(response to tellurium ion)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|interpro:IPR000590(Hydroxymethylglutaryl-coenzyme A synthase, active site)|interpro:IPR010122(Hydroxymethylglutaryl-CoA synthase, eukaryotic)|interpro:IPR013528(Hydroxymethylglutaryl-coenzyme A synthase, N-terminal)|interpro:IPR013746(Hydroxymethylglutaryl-coenzyme A synthase C-terminal)|interpro:IPR016039(Thiolase-like)|mint:Q01581|rcsb pdb:2P8U|reactome:R-HSA-191273|reactome:R-HSA-1989781|reactome:R-HSA-2426168|refseq:NP_001317592.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561 rogid:7txkOHhV1hUghX+s35oVhKsmS2c9606 rigid:ej5JnwVBem7Q1WbACmSX4AaZkrY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84560 uniprotkb:Q9UJX3 intact:EBI-22302898|ensemblbacteria:AAC68158 intact:EBI-1384164|uniprotkb:Q96AC4|uniprotkb:Q96GF4|uniprotkb:Q9BU24|uniprotkb:Q9NT16|ensembl:ENSP00000394394|ensembl:ENSP00000402314 psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name) psi-mi:apc7_human(display_long)|uniprotkb:ANAPC7(gene name)|psi-mi:ANAPC7(display_short)|uniprotkb:APC7(gene name synonym)|uniprotkb:Cyclosome subunit 7(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302905|imex:IM-27647-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68158(transcript)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_556(gene)|mint:O84560|refseq:WP_009872749.1|refseq:NP_220071.1 refseq:NP_001131136.1|refseq:NP_057322.2|dip:DIP-39765N|ensembl:ENSG00000196510(gene)|ensembl:ENST00000450008(transcript)|ensembl:ENST00000455511(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9UJX3|rcsb pdb:3FFL|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561 rogid:2q+llvuIzK2MOWjPuOUxmyN782E9606 rigid:ej5JnwVBem7Q1WbACmSX4AaZkrY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84560 uniprotkb:O94826 intact:EBI-22302898|ensemblbacteria:AAC68158 intact:EBI-2800236|uniprotkb:D3DN48|ensembl:ENSP00000284320 psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name) psi-mi:tom70_human(display_long)|uniprotkb:TOMM70(gene name)|psi-mi:TOMM70(display_short)|uniprotkb:KIAA0719(gene name synonym)|uniprotkb:TOM70(gene name synonym)|uniprotkb:TOMM70A(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym)|uniprotkb:Translocase of outer mitochondrial membrane protein 70(gene name synonym)|uniprotkb:Mitochondrial precursor proteins import receptor(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302905|imex:IM-27647-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68158(transcript)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_556(gene)|mint:O84560|refseq:WP_009872749.1|refseq:NP_220071.1 refseq:NP_055635.3|ensembl:ENSG00000154174(gene)|ensembl:ENST00000284320(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O94826|rcsb pdb:7DHG|rcsb pdb:7KDT|go:"GO:0005741"(mitochondrial outer membrane)|reactome:R-HSA-168928|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-1268020 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561 rogid:LtRXcptMA0w6Pv/4lksPfPJ4CYY9606 rigid:ej5JnwVBem7Q1WbACmSX4AaZkrY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84560 uniprotkb:Q58WW2 intact:EBI-22302898|ensemblbacteria:AAC68158 intact:EBI-2559044|ensembl:ENSP00000311949|uniprotkb:Q8TB19|uniprotkb:Q8IXH3|uniprotkb:A2A295|uniprotkb:Q7L8I0|uniprotkb:B4DNB8 psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name) psi-mi:dcaf6_human(display_long)|uniprotkb:DCAF6(gene name)|psi-mi:DCAF6(display_short)|uniprotkb:IQWD1(gene name synonym)|uniprotkb:Nuclear receptor interaction protein(gene name synonym)|uniprotkb:IQ motif and WD repeat-containing protein 1(gene name synonym)|uniprotkb:Androgen receptor complex-associated protein(gene name synonym)|uniprotkb:MSTP055(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302905|imex:IM-27647-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68158(transcript)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_556(gene)|mint:O84560|refseq:WP_009872749.1|refseq:NP_220071.1 ensembl:ENSG00000143164(gene)|ensembl:ENST00000312263(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|refseq:NP_001017977.1|refseq:NP_001185885.1|refseq:NP_001185886.1|refseq:NP_060912.2|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q58WW2|rcsb pdb:3I7O|reactome:R-HSA-8951664|dip:DIP-44678N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561 rogid:1CtoPWPj6fdryvDlC46pXiUguDc9606 rigid:ej5JnwVBem7Q1WbACmSX4AaZkrY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84560 uniprotkb:Q9Y2H6 intact:EBI-22302898|ensemblbacteria:AAC68158 intact:EBI-2810266|uniprotkb:Q6EVH4|uniprotkb:Q6N020|uniprotkb:B4DYG1|uniprotkb:Q5JVF8|uniprotkb:Q5HYC9|uniprotkb:Q6ZME4|uniprotkb:Q6P9D5|uniprotkb:Q6EVH3|uniprotkb:Q5JVF9|uniprotkb:Q9H1W1|ensembl:ENSP00000417257|ensembl:ENSP00000441831 psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name) psi-mi:fnd3a_human(display_long)|uniprotkb:FNDC3A(gene name)|psi-mi:FNDC3A(display_short)|uniprotkb:FNDC3(gene name synonym)|uniprotkb:HUGO(gene name synonym)|uniprotkb:KIAA0970(gene name synonym)|uniprotkb:Human gene expressed in odontoblasts(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302905|imex:IM-27647-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68158(transcript)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:CT_556(gene)|mint:O84560|refseq:WP_009872749.1|refseq:NP_220071.1 refseq:XP_016875929.1|refseq:XP_016875930.1|refseq:XP_016875931.1|refseq:NP_001073141.1|refseq:NP_055738.3|refseq:XP_011533299.1|ensembl:ENSG00000102531(gene)|ensembl:ENST00000492622(transcript)|ensembl:ENST00000541916(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0060009"(Sertoli cell development)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|mint:Q9Y2H6|rcsb pdb:1WK0|rcsb pdb:1X3D|rcsb pdb:1X4X|rcsb pdb:1X5X|rcsb pdb:2CRM|rcsb pdb:2CRZ|go:"GO:0016021"(integral component of membrane)|refseq:NP_001265367.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561 rogid:7gFZgxAfa590PH85SnEF3oeSNSI9606 rigid:ej5JnwVBem7Q1WbACmSX4AaZkrY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:O60610 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-3959709|uniprotkb:Q59FH8|uniprotkb:B7ZKW2|uniprotkb:A6NF18|uniprotkb:Q9UC76|intact:EBI-6137912|uniprotkb:E9PEZ2|uniprotkb:Q17RN4|ensembl:ENSP00000373706 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:diap1_human(display_long)|uniprotkb:DIAPH1(gene name)|psi-mi:DIAPH1(display_short)|uniprotkb:DIAP1(gene name synonym)|uniprotkb:Diaphanous-related formin-1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 refseq:NP_001073280.1|refseq:NP_005210.3|ensembl:ENSG00000131504(gene)|ensembl:ENST00000389054(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0072686"(mitotic spindle)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR010465(DRF autoregulatory)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027653|interpro:IPR042201|mint:O60610|reactome:R-HSA-5663220|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013405|reactome:R-HSA-9035034 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:m8uSwdWB9ePt8wzBRQBVujfEBfo9606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:Q8WXD5 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-752301|uniprotkb:Q53SI5|uniprotkb:Q8WVB4|uniprotkb:Q9H5G6|uniprotkb:B2RDP8|ensembl:ENSP00000281950 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:gemi6_human(display_long)|uniprotkb:SIP2(gene name synonym)|uniprotkb:GEMIN6(gene name)|psi-mi:GEMIN6(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 refseq:NP_079051.9|dip:DIP-41331N|ensembl:ENSG00000152147(gene)|ensembl:ENST00000281950(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR009422(Gemin6)|mint:Q8WXD5|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:AaQyOsKgOMpkny7dYKmgwu0/c1g9606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:Q9H4A6 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-2465479|uniprotkb:Q9UIW5|ensembl:ENSP00000265070 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:golp3_human(display_long)|uniprotkb:GOLPH3(gene name)|psi-mi:GOLPH3(display_short)|uniprotkb:GPP34(gene name synonym)|uniprotkb:Coat protein GPP34(gene name synonym)|uniprotkb:Mitochondrial DNA absence factor(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 refseq:NP_071413.1|ensembl:ENSG00000113384(gene)|ensembl:ENST00000265070(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0009306"(protein secretion)|go:"GO:0010467"(gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090164"(asymmetric Golgi ribbon formation)|interpro:IPR008628(Golgi phosphoprotein 3)|interpro:IPR038261|mint:Q9H4A6|rcsb pdb:3KN1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:tHHREhHksCP+Yf9FzycM9cI+wkc9606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:P04637 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:Q96HR8 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-2515597|ensembl:ENSP00000274054|uniprotkb:D3DP28|uniprotkb:E9PAZ2 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:naf1_human(display_long)|uniprotkb:NAF1(gene name)|psi-mi:NAF1(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 ensembl:ENSG00000145414(gene)|ensembl:ENST00000274054(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0000493"(box H/ACA snoRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043489"(RNA stabilization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090669"(telomerase RNA stabilization)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|interpro:IPR040309|mint:Q96HR8|rcsb pdb:2EQN|interpro:IPR007504(Gar1 protein RNA-binding region)|refseq:XP_011530712.1|refseq:NP_001122403.1|refseq:NP_612395.2 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:RN78Bx9nJvfGDvaezT/U4TUf2KY9606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:Q07065 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-702400|uniprotkb:Q504S5|uniprotkb:Q53ES6|ensembl:ENSP00000367265 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:ckap4_human(display_long)|uniprotkb:CKAP4(gene name)|psi-mi:CKAP4(display_short)|uniprotkb:63-kDa cytoskeleton-linking membrane protein(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 refseq:NP_006816.2|ensembl:ENSG00000136026(gene)|ensembl:ENST00000378026(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042599"(lamellar body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028428|mint:Q07065|reactome:R-HSA-381426|reactome:R-HSA-5683826|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:Q1hrxqh5k4Myf7J0To8Ecm/xxs49606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:Q9UHI6 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-347658|uniprotkb:Q96F72|uniprotkb:Q9NVM3|uniprotkb:Q9UF59|uniprotkb:Q9UIY0|uniprotkb:Q9Y659|uniprotkb:B4DWV7|ensembl:ENSP00000358716|ensembl:ENSP00000505857 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:ddx20_human(display_long)|uniprotkb:DDX20(gene name)|psi-mi:DDX20(display_short)|uniprotkb:DP103(gene name synonym)|uniprotkb:GEMIN3(gene name synonym)|uniprotkb:DEAD box protein 20(gene name synonym)|uniprotkb:DEAD box protein DP 103(gene name synonym)|uniprotkb:Component of gems 3(gene name synonym)|uniprotkb:Gemin-3(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 refseq:NP_009135.4|ensembl:ENSP00000358716|ensembl:ENST00000533164|ensembl:ENSP00000434085|ensembl:ENSP00000505857|dip:DIP-32606N|ensembl:ENSG00000064703(gene)|ensembl:ENST00000369702(transcript)|ensembl:ENST00000679724(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006396"(RNA processing)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050810"(regulation of steroid biosynthetic process)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0097504"(Gemini of coiled bodies)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9UHI6|rcsb pdb:2OXC|rcsb pdb:3B7G|reactome:R-HSA-191859|go:"GO:0043065"(positive regulation of apoptotic process) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:Q9IGbhb825yL12imyTlBAHZ4YyU9606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:O95347 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-355822|intact:EBI-1058371|uniprotkb:Q9P1P2|uniprotkb:Q6IEE0|ensembl:ENSP00000286398|ensembl:ENSP00000363919|ensembl:ENSP00000363925 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:smc2_human(display_long)|uniprotkb:PRO0324(orf name)|uniprotkb:SMC2(gene name)|psi-mi:SMC2(display_short)|uniprotkb:CAPE(gene name synonym)|uniprotkb:SMC2L1(gene name synonym)|uniprotkb:Chromosome-associated protein E(gene name synonym)|uniprotkb:XCAP-E homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 refseq:NP_001036015.1|refseq:NP_001036016.1|refseq:NP_006435.2|refseq:XP_011516451.1|refseq:XP_011516455.1|refseq:XP_011516450.1|refseq:NP_001252531.1|refseq:XP_006716996.1|refseq:XP_016869695.1|refseq:XP_016869696.1|refseq:XP_016869697.1|dip:DIP-35422N|ensembl:ENSG00000136824(gene)|ensembl:ENST00000286398(transcript)|ensembl:ENST00000374787(transcript)|ensembl:ENST00000374793(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027120|interpro:IPR027417|interpro:IPR036277|mint:O95347|rcsb pdb:4U4P|reactome:R-HSA-2299718|reactome:R-HSA-2514853 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:k7RHRDmgiucuAOIfh8vjbqnlv3E9606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:Q86VP6 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-456077|uniprotkb:O94918|uniprotkb:Q6PIY4|uniprotkb:Q8NDJ4|uniprotkb:Q96JZ9|uniprotkb:Q96T19|uniprotkb:Q9BTC4|uniprotkb:Q9H0G2|uniprotkb:Q9P0H7|uniprotkb:Q9UF85|uniprotkb:B2RAU3|ensembl:ENSP00000442318 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:cand1_human(display_long)|uniprotkb:KIAA0829(gene name synonym)|uniprotkb:TIP120(gene name synonym)|uniprotkb:TIP120A(gene name synonym)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:p120 CAND1(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa A(gene name synonym)|uniprotkb:CAND1(gene name)|psi-mi:CAND1(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 refseq:NP_060918.2|dip:DIP-31608N|ensembl:ENSG00000111530(gene)|ensembl:ENST00000545606(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR039852|mint:Q86VP6|rcsb pdb:1U6G|rcsb pdb:4A0C|reactome:R-HSA-6798695|reactome:R-HSA-8951664|reactome:R-HSA-917937|interpro:IPR016024(Armadillo-type fold) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:2lBY8xJXlGZL+xyo/dyB2WzuNqs9606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:P42695 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-722805|uniprotkb:A6NFS2|uniprotkb:Q4KMQ9|ensembl:ENSP00000433681 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:cndd3_human(display_long)|uniprotkb:Non-SMC condensin II complex subunit D3(gene name synonym)|uniprotkb:NCAPD3(gene name)|psi-mi:NCAPD3(display_short)|uniprotkb:CAPD3(gene name synonym)|uniprotkb:KIAA0056(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 refseq:NP_056076.1|dip:DIP-43903N|ensembl:ENSG00000151503(gene)|ensembl:ENST00000534548(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012371(Chromosome condensation protein, HCP-6-related)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026971|interpro:IPR032682|mint:P42695|reactome:R-HSA-2299718 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:z5WYLlrGt33uAM9NRN9SQeHFDaA9606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:Q86UD0 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-2561646|ensembl:ENSP00000386348 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:sapc2_human(display_long)|uniprotkb:SAPCD2(gene name)|psi-mi:SAPCD2(display_short)|uniprotkb:C9orf140(gene name synonym)|uniprotkb:Tumor specificity and mitosis phase-dependent expression protein(gene name synonym)|uniprotkb:p42.3(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 refseq:NP_848543.2|ensembl:ENSG00000186193(gene)|ensembl:ENST00000409687(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0043296"(apical junction complex)|go:"GO:0045179"(apical cortex)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0098725"(symmetric cell division)|go:"GO:1904777"(negative regulation of protein localization to cell cortex)|interpro:IPR026828|mint:Q86UD0 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:P07CYw5xvvMZxL3MdRzOVP1fLQg9606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:P55010 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-286450|uniprotkb:Q9H5N2|uniprotkb:Q9UG48|uniprotkb:Q53XB3|ensembl:ENSP00000216554|ensembl:ENSP00000376477|ensembl:ENSP00000453743 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:if5_human(display_long)|uniprotkb:EIF5(gene name)|psi-mi:EIF5(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 refseq:NP_001960.2|refseq:NP_892116.2|ensembl:ENSG00000100664(gene)|ensembl:ENST00000216554(transcript)|ensembl:ENST00000392715(transcript)|ensembl:ENST00000558506(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|mint:P55010|rcsb pdb:2E9H|rcsb pdb:2G2K|rcsb pdb:2IU1|reactome:R-HSA-72702|reactome:R-HSA-72706 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:lM5AZJWJOQGbxADfl8MGCx3JAXc9606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:P56182 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-2880285|ensembl:ENSP00000417464|uniprotkb:Q9NST5 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:rrp1_human(display_long)|uniprotkb:RRP1(gene name)|psi-mi:RRP1(display_short)|uniprotkb:D21S2056E(gene name synonym)|uniprotkb:NNP1(gene name synonym)|uniprotkb:NOP52(gene name synonym)|uniprotkb:RRP1A(gene name synonym)|uniprotkb:Novel nuclear protein 1(gene name synonym)|uniprotkb:Nucleolar protein Nop52(gene name synonym)|uniprotkb:RRP1-like protein(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 ensembl:ENSG00000160214(gene)|ensembl:ENST00000497547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR010301(Nucleolar, Nop52)|mint:P56182|reactome:R-HSA-6791226|refseq:NP_003674.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:Soi88HwcPgF0DZiSK8fwKkslHGI9606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:Q9BT22 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-6268721|uniprotkb:B4DP08|ensembl:ENSP00000262374|uniprotkb:Q6UVZ9|uniprotkb:Q8N5Y4|uniprotkb:Q9P2Y2 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:alg1_human(display_long)|uniprotkb:ALG1(gene name)|psi-mi:ALG1(display_short)|uniprotkb:HMAT1(gene name synonym)|uniprotkb:HMT1(gene name synonym)|uniprotkb:Asparagine-linked glycosylation protein 1 homolog(gene name synonym)|uniprotkb:Beta-1,4-mannosyltransferase(gene name synonym)|uniprotkb:"GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase"(gene name synonym)|uniprotkb:GDP-mannose-dolichol diphosphochitobiose mannosyltransferase(gene name synonym)|uniprotkb:Mannosyltransferase-1(gene name synonym)|uniprotkb:PSEC0061(orf name)|uniprotkb:UNQ861/PRO1870(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 ensembl:ENSG00000033011(gene)|go:"GO:0000030"(mannosyltransferase activity)|go:"GO:0004578"(chitobiosyldiphosphodolichol beta-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001296(Glycosyl transferase, group 1)|interpro:IPR026051|mint:Q9BT22|reactome:R-HSA-446193|reactome:R-HSA-4549380|ensembl:ENST00000262374(transcript)|refseq:NP_061982.3|refseq:NP_001317433.1|refseq:XP_016878947.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:ssuj2ltO7juusnd1BHWPqAsYdV09606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:Q6IBW4 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-2548296|ensembl:ENSP00000410088|uniprotkb:Q9BUT3|uniprotkb:Q9BVD1|uniprotkb:B7WPH1|uniprotkb:O43788|uniprotkb:Q13391|uniprotkb:Q96C14|uniprotkb:Q96GJ0|uniprotkb:Q9BQ71 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:cndh2_human(display_long)|uniprotkb:NCAPH2(gene name)|psi-mi:NCAPH2(display_short)|uniprotkb:CAPH2(gene name synonym)|uniprotkb:Non-SMC condensin II complex subunit H2(gene name synonym)|uniprotkb:Chromosome-associated protein H2(gene name synonym)|uniprotkb:Kleisin-beta(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 ensembl:ENSG00000025770(gene)|ensembl:ENST00000420993(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0051309"(female meiosis chromosome separation)|interpro:IPR009378(Protein of unknown function DUF1032)|interpro:IPR031719|interpro:IPR031737|interpro:IPR031739|mint:Q6IBW4|reactome:R-HSA-2299718|refseq:NP_001171940.1|refseq:NP_055366.3|refseq:NP_689512.2|dip:DIP-43901N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:GTOZg0OoAHm+tj3C8/3sCGM+G5E9606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:Q86U38 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-5456022|uniprotkb:Q8IVF0|uniprotkb:Q8TBS6|intact:EBI-8293740|intact:MINT-8407174|uniprotkb:A8MY76|ensembl:ENSP00000267425|ensembl:ENSP00000495668 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:nop9_human(display_long)|uniprotkb:NOP9(gene name)|psi-mi:NOP9(display_short)|uniprotkb:C14orf21(gene name synonym)|uniprotkb:KIAA2021(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 refseq:NP_001273296.1|refseq:NP_777573.1|ensembl:ENSG00000196943(gene)|ensembl:ENSG00000285326(gene)|ensembl:ENST00000267425(transcript)|ensembl:ENST00000644840(transcript)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040000|mint:Q86U38 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:dJjEtwyK4x6qVx2dW0MzS7tqDYI9606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:Q7Z4Q2 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-1051903|uniprotkb:Q8N525|uniprotkb:Q8WV56|uniprotkb:Q96CC9|uniprotkb:Q9NWN7|uniprotkb:A8K1N4|ensembl:ENSP00000299192 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:heat3_human(display_long)|uniprotkb:HEATR3(gene name)|psi-mi:HEATR3(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 refseq:NP_891552.1|ensembl:ENSG00000155393(gene)|ensembl:ENST00000299192(transcript)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR016024(Armadillo-type fold)|mint:Q7Z4Q2 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:CjdYLKIHc/A29+XYy4VjNNHJSRU9606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:P78347 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-359622|uniprotkb:Q75M88|uniprotkb:O14743|uniprotkb:O15359|uniprotkb:O43546|uniprotkb:O43588|uniprotkb:O43589|uniprotkb:Q9BSZ4|uniprotkb:Q86U51|uniprotkb:Q75M85|uniprotkb:Q75M86|uniprotkb:Q75M87|ensembl:ENSP00000460070 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:gtf2i_human(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 refseq:NP_001509.3|refseq:NP_127492.1|refseq:NP_127493.1|refseq:NP_127494.1|ensembl:ENSG00000263001(gene)|ensembl:ENST00000573035(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0100026"(positive regulation of DNA repair by transcription from RNA polymerase II promoter)|interpro:IPR004212(GTF2I-like repeat)|interpro:IPR016659(Transcription factor II-I)|mint:P78347|rcsb pdb:2D9B|rcsb pdb:2DN4|rcsb pdb:2ED2|rcsb pdb:2EJE|interpro:IPR036647|refseq:NP_001157108.1|refseq:NP_001267729.1|dip:DIP-24252N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:DqfrIS0Ey+XvZfTXmk9KQzBtQo49606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:Q86XI2 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-1047404|uniprotkb:Q7Z3J9|uniprotkb:Q8WUG8|uniprotkb:Q9BRX6|uniprotkb:Q9H8S2|uniprotkb:Q9H9K6|uniprotkb:A4D228|ensembl:ENSP00000348657|ensembl:ENSP00000386569 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:cndg2_human(display_long)|uniprotkb:Chromosome-associated protein G2(gene name synonym)|uniprotkb:Non-SMC condensin II complex subunit G2(gene name synonym)|uniprotkb:Leucine zipper protein 5(gene name synonym)|uniprotkb:NCAPG2(gene name)|psi-mi:NCAPG2(display_short)|uniprotkb:LUZP5(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 refseq:NP_060230.5|refseq:XP_011514658.1|refseq:XP_011514659.1|ensembl:ENSG00000146918(gene)|ensembl:ENST00000356309(transcript)|ensembl:ENST00000409423(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000796"(condensin complex)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030293"(transmembrane receptor protein tyrosine kinase inhibitor activity)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0051301"(cell division)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024741|mint:Q86XI2|reactome:R-HSA-2299718|interpro:IPR011989(Armadillo-like helical)|refseq:NP_001268861.1|refseq:NP_001268862.1|dip:DIP-43902N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:4JkTPdyKz1cYblG0ZU0vQKMsuB49606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:Q9NSV4 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-1050601|uniprotkb:A2A3B8|uniprotkb:A2A3B9|uniprotkb:A2A3C0|uniprotkb:Q18P99|uniprotkb:Q18PA0|uniprotkb:Q18PA1|uniprotkb:Q2KPB6|uniprotkb:Q3ZK23|uniprotkb:Q5JTP8|uniprotkb:Q5T2S7|uniprotkb:Q5XKF6|uniprotkb:Q6MZF0|uniprotkb:Q6NUP0|uniprotkb:Q86VS4|uniprotkb:Q8NAV4|ensembl:ENSP00000383178 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:diap3_human(display_long)|uniprotkb:Diaphanous-related formin-3(gene name synonym)|uniprotkb:DIAPH3(gene name)|psi-mi:DIAPH3(display_short)|uniprotkb:DIAP3(gene name synonym)|uniprotkb:MDia2(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 refseq:NP_001035982.1|refseq:NP_112194.2|refseq:NP_001245295.1|refseq:NP_001245296.1|refseq:NP_001245297.1|refseq:NP_001245298.1|refseq:NP_001245299.1|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|ensembl:ENSG00000139734(gene)|ensembl:ENST00000400324(transcript)|go:"GO:0045296"(cadherin binding)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027654|interpro:IPR042201|interpro:IPR010465(DRF autoregulatory)|mint:Q9NSV4|rcsb pdb:5UWP|rcsb pdb:6X2Y|reactome:R-HSA-5663220|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:noy8LGt6F+8an19X1WyEqSqpAYk9606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:O75155 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-5656182|uniprotkb:B9EGM9|uniprotkb:E9KL24|ensembl:ENSP00000387641 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:cand2_human(display_long)|uniprotkb:Cullin-associated and neddylation-dissociated protein 2(gene name synonym)|uniprotkb:KIAA0667(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa B(gene name synonym)|uniprotkb:TIP120B(gene name synonym)|uniprotkb:p120 CAND2(gene name synonym)|uniprotkb:CAND2(gene name)|psi-mi:CAND2(display_short)|uniprotkb:Epididymis tissue protein Li 169(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 refseq:NP_001155971.1|refseq:NP_036430.1|ensembl:ENSG00000144712(gene)|ensembl:ENST00000456430(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039852|mint:O75155 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:LKo/B25pZVSPOAE+Yvk/ug1o7xY9606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:Q27J81 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-2557882|uniprotkb:Q6PK22|uniprotkb:Q86TR7|uniprotkb:Q9H6N1|uniprotkb:Q9BRM1|uniprotkb:Q27J83|uniprotkb:Q69YL8|uniprotkb:Q6P1X7|intact:EBI-28987364|ensembl:ENSP00000376410 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:inf2_human(display_long)|uniprotkb:INF2(gene name)|psi-mi:INF2(display_short)|uniprotkb:C14orf151(gene name synonym)|uniprotkb:C14orf173(gene name synonym)|uniprotkb:HBEBP2-binding protein C(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 refseq:NP_001026884.3|refseq:NP_071934.3|refseq:NP_116103.1|ensembl:ENSG00000203485(gene)|ensembl:ENST00000392634(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090140"(regulation of mitochondrial fission)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|mint:Q27J81|interpro:IPR027649|interpro:IPR042201|ensembl:ENST00000330634|ensembl:ENSP00000376406|ensembl:ENSP00000376410|ensembl:ENST00000398337|ensembl:ENSP00000381380 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:Vtx6fZtKGr2qGWX70naf5REXWTw9606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:Q12770 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-6190187|ensembl:ENSP00000265565|ensembl:ENSP00000497087|uniprotkb:Q8N2E0|uniprotkb:Q8WUA1 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:scap_human(display_long)|uniprotkb:SCAP(gene name)|psi-mi:SCAP(display_short)|uniprotkb:KIAA0199(gene name synonym)|uniprotkb:PSEC0227(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 ensembl:ENSG00000114650(gene)|ensembl:ENST00000648151(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006955"(immune response)|go:"GO:0007568"(aging)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032868"(response to insulin)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032934"(sterol binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042304"(regulation of fatty acid biosynthetic process)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|ensembl:ENST00000265565(transcript)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR030225|interpro:IPR036322|mint:Q12770|rcsb pdb:6M49|rcsb pdb:7ETW|reactome:R-HSA-1655829|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|refseq:XP_011531803.1|refseq:NP_036367.2|refseq:XP_016861407.1|refseq:XP_016861410.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:bhavwLS6XzkZpAoBhCsII97JfpI9606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84793 uniprotkb:O60293 intact:EBI-22302928|ensemblbacteria:AAC68383 intact:EBI-746701|intact:EBI-2874127|uniprotkb:Q6GMU1|uniprotkb:Q6P2S9|uniprotkb:Q6ZV36|uniprotkb:Q96BE7|ensembl:ENSP00000368017 psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name) psi-mi:zc3h1_human(display_long)|uniprotkb:Proline/serine-rich coiled-coil protein 2(gene name synonym)|uniprotkb:ZFC3H1(gene name)|psi-mi:ZFC3H1(display_short)|uniprotkb:KIAA0546(gene name synonym)|uniprotkb:PSRC2(gene name synonym)|uniprotkb:CCDC131(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 131(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22302936|imex:IM-27647-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68383(transcript)|ensemblbacteria:CT_788(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84793|refseq:NP_220307.1|refseq:WP_010725345.1|interpro:IPR025640 refseq:NP_659419.3|ensembl:ENSG00000133858(gene)|ensembl:ENST00000378743(transcript)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006396"(RNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019607|interpro:IPR039278|mint:O60293|ensembl:ENSP00000368017|ensembl:ENST00000548100|ensembl:ENSP00000450044|ensembl:ENST00000552994|ensembl:ENSP00000446995 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/11 rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561 rogid:QJlOZNAOi6leWMDpXLZH6hYjMOk9606 rigid:dyi93G0CJxGxBDN+i9ubprFzfzI false strep tag:c-c|binding-associated region:26-166 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3E0 uniprotkb:O84447 intact:EBI-4402607|uniprotkb:B2R4R4|uniprotkb:Q54A40|uniprotkb:Q6I9W6|uniprotkb:Q9P1R9|ensembl:ENSP00000229314 intact:EBI-22303381|ensemblbacteria:AAC68039 psi-mi:got1b_human(display_long)|uniprotkb:GOLT1B(gene name)|psi-mi:GOLT1B(display_short)|uniprotkb:GOT1A(gene name synonym)|uniprotkb:Golgi transport 1 homolog B(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 470(gene name synonym)|uniprotkb:hGOT1a(gene name synonym)|uniprotkb:CGI-141(orf name)|uniprotkb:HDCMA39P(orf name)|uniprotkb:UNQ432/PRO793(orf name)|uniprotkb:GCT2(gene name synonym)|uniprotkb:Germ cell tumor 2(gene name synonym) psi-mi:o84447_chltr(display_long)|uniprotkb:CT_440(locus name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:272561(chltr)|taxid:272561(chltr) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22303388|imex:IM-27647-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057156.1|ensembl:ENSG00000111711(gene)|ensembl:ENST00000229314(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR007305(Got1-like protein)|mint:Q9Y3E0 ensemblbacteria:AAC68039(transcript)|ensemblbacteria:CT_440(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84447|refseq:NP_219952.1|refseq:WP_009871795.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:dvlUtRzzjPZ9BTUtxhy2Sb3KB4Q9606 rogid:gu5tPovGP6iBBdfPTQozB6nZ8xQ272561 rigid:7M2ieNq9C07a24Xb5uO97mNPE9c false - strep tag:c-c - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84449 uniprotkb:Q9Y4L1 intact:EBI-22303394|ensemblbacteria:AAC68041 intact:EBI-1054186|uniprotkb:Q2I204|uniprotkb:Q53H25|uniprotkb:B7Z909|uniprotkb:A8C1Z0|ensembl:ENSP00000480150|ensembl:ENSP00000486825 psi-mi:srpd_chltr(display_long)|uniprotkb:15 kDa cysteine-rich outer membrane protein(gene name synonym)|uniprotkb:Cysteine-rich protein A(gene name synonym)|uniprotkb:srp(gene name)|psi-mi:srp(display_short)|uniprotkb:crpA(gene name synonym)|uniprotkb:CT_442(locus name) psi-mi:hyou1_human(display_long)|uniprotkb:150 kDa oxygen-regulated protein(gene name synonym)|uniprotkb:GRP170(gene name synonym)|uniprotkb:HYOU1(gene name)|psi-mi:HYOU1(display_short)|uniprotkb:ORP150(gene name synonym)|uniprotkb:170 kDa glucose-regulated protein(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303405|imex:IM-27647-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68041(transcript)|ensemblbacteria:CT_442(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019867"(outer membrane)|mint:O84449|refseq:NP_219954.1|refseq:WP_009872659.1|interpro:IPR008436(Chlamydia 15 kDa cysteine-rich outer membrane) refseq:NP_001124463.1|refseq:NP_006380.1|refseq:XP_016872585.1|refseq:XP_016872586.1|ensembl:ENSG00000149428(gene)|ensembl:ENSG00000280682(gene)|ensembl:ENST00000617285(transcript)|ensembl:ENST00000630669(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005925"(focal adhesion)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:Q9Y4L1|reactome:R-HSA-3000484|reactome:R-HSA-381038|go:"GO:0005790"(smooth endoplasmic reticulum) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:/Tyk9fBlumPf1mfHsWYTn13A2wQ272561 rogid:xqSFRaiiHJLNVqgh87tHx9lfnS49606 rigid:8fJymttFvuXmCE3KGLJqP+VFfpU false binding-associated region:71-150|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84449 uniprotkb:Q9NR09 intact:EBI-22303394|ensemblbacteria:AAC68041 intact:EBI-1765160|uniprotkb:Q9ULD1|ensembl:ENSP00000393596 psi-mi:srpd_chltr(display_long)|uniprotkb:15 kDa cysteine-rich outer membrane protein(gene name synonym)|uniprotkb:Cysteine-rich protein A(gene name synonym)|uniprotkb:srp(gene name)|psi-mi:srp(display_short)|uniprotkb:crpA(gene name synonym)|uniprotkb:CT_442(locus name) psi-mi:birc6_human(display_long)|uniprotkb:BIRC6(gene name)|psi-mi:BIRC6(display_short)|uniprotkb:KIAA1289(gene name synonym)|uniprotkb:Ubiquitin-conjugating BIR domain enzyme apollon(gene name synonym)|uniprotkb:BIR repeat-containing ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC6(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303405|imex:IM-27647-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68041(transcript)|ensemblbacteria:CT_442(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019867"(outer membrane)|mint:O84449|refseq:NP_219954.1|refseq:WP_009872659.1|interpro:IPR008436(Chlamydia 15 kDa cysteine-rich outer membrane) refseq:NP_057336.3|ensembl:ENSG00000115760(gene)|ensembl:ENST00000421745(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051301"(cell division)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:0060712"(spongiotrophoblast layer development)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0090543"(Flemming body)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR022103|mint:Q9NR09|rcsb pdb:3CEG - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:/Tyk9fBlumPf1mfHsWYTn13A2wQ272561 rogid:/EZap+9dFkEnO5fRsbzriORwllk9606 rigid:8fJymttFvuXmCE3KGLJqP+VFfpU false binding-associated region:71-150|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84648 uniprotkb:Q9GZT3 intact:EBI-22303572|ensemblbacteria:AAC68246 intact:EBI-1050793|uniprotkb:J3KMY7|ensembl:ENSP00000450909|intact:EBI-10967524 psi-mi:o84648_chltr(display_long)|uniprotkb:CT_642(locus name) psi-mi:slirp_human(display_long)|uniprotkb:SLIRP(gene name)|psi-mi:SLIRP(display_short)|uniprotkb:C14orf156(gene name synonym)|uniprotkb:DC23(orf name)|uniprotkb:DC50(orf name)|uniprotkb:PD04872(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303579|imex:IM-27647-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68246(transcript)|ensemblbacteria:CT_642(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84648|refseq:NP_220160.1|refseq:WP_010725287.1 refseq:NP_112487.1|refseq:NP_001254792.1|refseq:NP_001254793.1|ensembl:ENSG00000119705(gene)|ensembl:ENST00000557342(transcript)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007286"(spermatid development)|go:"GO:0007338"(single fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0036126"(sperm flagellum)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034152|interpro:IPR035979|mint:Q9GZT3 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:qYRqhfb71UQRiktdWgcoiYBQXTI272561 rogid:8sPWOtmxPTOVlthXwBiIIp/+6go9606 rigid:P3RQbtPEPUu4WXnXQp/0hA9BwB4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84648 uniprotkb:P42704 intact:EBI-22303572|ensemblbacteria:AAC68246 intact:EBI-1050853|uniprotkb:A0PJE3|uniprotkb:A8K1V1|uniprotkb:Q53PC0|uniprotkb:Q53QN7|uniprotkb:Q96D84|uniprotkb:Q6ZUD8|uniprotkb:Q7Z7A6|ensembl:ENSP00000260665 psi-mi:o84648_chltr(display_long)|uniprotkb:CT_642(locus name) psi-mi:lpprc_human(display_long)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)|uniprotkb:GP130(gene name synonym)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:LRP130(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303579|imex:IM-27647-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68246(transcript)|ensemblbacteria:CT_642(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84648|refseq:NP_220160.1|refseq:WP_010725287.1 refseq:NP_573566.2|ensembl:ENSG00000138095(gene)|ensembl:ENST00000260665(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:P42704|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|dip:DIP-27543N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:qYRqhfb71UQRiktdWgcoiYBQXTI272561 rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606 rigid:P3RQbtPEPUu4WXnXQp/0hA9BwB4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84648 uniprotkb:Q9ULH0 intact:EBI-22303572|ensemblbacteria:AAC68246 intact:EBI-716681|uniprotkb:A1L4N4|intact:EBI-2798329|uniprotkb:Q6MZU2|uniprotkb:Q9H889|uniprotkb:Q9H9E4|uniprotkb:Q9NT37|uniprotkb:Q9UF42|uniprotkb:Q4VC08|ensembl:ENSP00000256707 psi-mi:o84648_chltr(display_long)|uniprotkb:CT_642(locus name) psi-mi:kdis_human(display_long)|uniprotkb:KIAA1250(gene name synonym)|uniprotkb:KIDINS220(gene name)|psi-mi:KIDINS220(display_short)|uniprotkb:ARMS(gene name synonym)|uniprotkb:Ankyrin repeat-rich membrane-spanning protein(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303579|imex:IM-27647-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68246(transcript)|ensemblbacteria:CT_642(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84648|refseq:NP_220160.1|refseq:WP_010725287.1 refseq:NP_065789.1|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000134313(gene)|ensembl:ENST00000256707(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR002110(Ankyrin)|interpro:IPR011646(KAP P-loop)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|mint:Q9ULH0|reactome:R-HSA-170984|reactome:R-HSA-9696270|reactome:R-HSA-9696273 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:qYRqhfb71UQRiktdWgcoiYBQXTI272561 rogid:0wyaXuvXCqQTlfjuW4TAcIGmdlw9606 rigid:P3RQbtPEPUu4WXnXQp/0hA9BwB4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84648 uniprotkb:Q92930 intact:EBI-22303572|ensemblbacteria:AAC68246 intact:EBI-1760095|uniprotkb:Q9P293|uniprotkb:Q5JPC4|ensembl:ENSP00000312734 psi-mi:o84648_chltr(display_long)|uniprotkb:CT_642(locus name) psi-mi:rab8b_human(display_long)|uniprotkb:RAB8B(gene name)|psi-mi:RAB8B(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303579|imex:IM-27647-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68246(transcript)|ensemblbacteria:CT_642(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84648|refseq:NP_220160.1|refseq:WP_010725287.1 refseq:NP_057614.1|ensembl:ENSG00000166128(gene)|ensembl:ENST00000321437(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0016604"(nuclear body)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051286"(cell tip)|go:"GO:0051461"(positive regulation of corticotropin secretion)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0150115"(cell-substrate junction organization)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q92930|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:qYRqhfb71UQRiktdWgcoiYBQXTI272561 rogid:1EzHoU6jEdli/t9gfwMBDjW3fNI9606 rigid:P3RQbtPEPUu4WXnXQp/0hA9BwB4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84648 uniprotkb:Q14534 intact:EBI-22303572|ensemblbacteria:AAC68246 intact:EBI-3905171|uniprotkb:Q9UEK6|ensembl:ENSP00000265896|uniprotkb:Q9UNR6 psi-mi:o84648_chltr(display_long)|uniprotkb:CT_642(locus name) psi-mi:erg1_human(display_long)|uniprotkb:SQLE(gene name)|psi-mi:SQLE(display_short)|uniprotkb:ERG1(gene name synonym)|uniprotkb:Squalene epoxidase(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303579|imex:IM-27647-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68246(transcript)|ensemblbacteria:CT_642(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84648|refseq:NP_220160.1|refseq:WP_010725287.1 refseq:NP_003120.2|ensembl:ENSG00000104549(gene)|go:"GO:0004506"(squalene monooxygenase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006725"(cellular aromatic compound metabolic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071949"(FAD binding)|go:"GO:0140042"(lipid droplet formation)|interpro:IPR013698(Squalene epoxidase)|interpro:IPR036188|interpro:IPR040125|mint:Q14534|rcsb pdb:6C6N|rcsb pdb:6C6P|rcsb pdb:6C6R|reactome:R-HSA-191273|reactome:R-HSA-2426168|ensembl:ENST00000265896(transcript) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:qYRqhfb71UQRiktdWgcoiYBQXTI272561 rogid:jZnV6eRSD75A7YVspfL6SBq8XkA9606 rigid:P3RQbtPEPUu4WXnXQp/0hA9BwB4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:O84623 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-22303612|ensemblbacteria:AAC68222 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:o84623_chltr(display_long)|uniprotkb:CT_618(locus name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:272561(chltr)|taxid:272561(chltr) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22303619|imex:IM-27647-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N ensemblbacteria:AAC68222(transcript)|ensemblbacteria:CT_618(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84623|refseq:NP_220135.1|refseq:WP_010725275.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:jrgFj+3qHniid9gbFfQSpN1v0yg272561 rigid:HYB7/wNAJZwGAdM3NiCnEp+fxls false - binding-associated region:1-214|strep tag:c-c - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NR45 uniprotkb:O84623 intact:EBI-709675|uniprotkb:Q8WUV9|uniprotkb:Q9BWS6|uniprotkb:Q9NVD4|uniprotkb:B2RE98|ensembl:ENSP00000210444 intact:EBI-22303612|ensemblbacteria:AAC68222 psi-mi:sias_human(display_long)|uniprotkb:N-acetylneuraminate synthase(gene name synonym)|uniprotkb:N-acetylneuraminic acid synthase(gene name synonym)|uniprotkb:N-acetylneuraminate-9-phosphate synthase(gene name synonym)|uniprotkb:N-acetylneuraminic acid phosphate synthase(gene name synonym)|uniprotkb:NANS(gene name)|psi-mi:NANS(display_short)|uniprotkb:SAS(gene name synonym) psi-mi:o84623_chltr(display_long)|uniprotkb:CT_618(locus name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:272561(chltr)|taxid:272561(chltr) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22303627|imex:IM-27647-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061819.2|ensembl:ENSG00000095380(gene)|ensembl:ENST00000210444(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006055"(CMP-N-acetylneuraminate biosynthetic process)|go:"GO:0008781"(N-acylneuraminate cytidylyltransferase activity)|go:"GO:0016051"(carbohydrate biosynthetic process)|go:"GO:0047444"(N-acylneuraminate-9-phosphate synthase activity)|go:"GO:0050462"(N-acetylneuraminate synthase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070085"(glycosylation)|interpro:IPR006013(Antifreeze, type III)|interpro:IPR006190(Antifreeze-like/N-acetylneuraminic acid synthase C-terminal)|interpro:IPR013132(N-acetylneuraminic acid synthase, N-terminal)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR013974(SAF domain)|interpro:IPR036732|mint:Q9NR45|rcsb pdb:1WVO|reactome:R-HSA-4085001 ensemblbacteria:AAC68222(transcript)|ensemblbacteria:CT_618(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84623|refseq:NP_220135.1|refseq:WP_010725275.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:kdMBtQ/FC9c+6Bi79j1RkkifZ2k9606 rogid:jrgFj+3qHniid9gbFfQSpN1v0yg272561 rigid:4oHZMztWCXrp5wCWqQl3f/cyX6g false - strep tag:c-c - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84733 uniprotkb:P0CG08 intact:EBI-22303635|ensemblbacteria:AAC68323 intact:EBI-11905631|ensembl:ENSP00000358233|uniprotkb:A6NKF9|uniprotkb:A6NN37|uniprotkb:B2RUV3|uniprotkb:B3KMN3|uniprotkb:Q53FQ9|uniprotkb:Q5T2V8|uniprotkb:Q5T5P5|uniprotkb:Q659E2|uniprotkb:Q6NVY5|uniprotkb:Q9P0S4|uniprotkb:Q9Y302 psi-mi:o84733_chltr(display_long)|uniprotkb:CT_728(locus name) psi-mi:gphrb_human(display_long)|uniprotkb:GPR89B(gene name)|psi-mi:GPR89B(display_short)|uniprotkb:GPHRB(gene name synonym)|uniprotkb:GPR89C(gene name synonym)|uniprotkb:Protein GPR89B(gene name synonym)|uniprotkb:HSPC201(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303646|imex:IM-27647-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68323(transcript)|ensemblbacteria:CT_728(gene)|go:"GO:0005384"(manganese ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030026"(cellular manganese ion homeostasis)|mint:O84733|refseq:NP_220247.1|refseq:WP_009872105.1|interpro:IPR008217(Protein of unknown function DUF125, transmembrane) ensembl:ENSG00000188092(gene)|ensembl:ENST00000314163(transcript)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0051452"(intracellular pH reduction)|interpro:IPR015672(G-protein coupled receptor 89-related)|interpro:IPR022535|interpro:IPR025969|mint:P0CG08|refseq:NP_001091081.1|refseq:NP_057418.1|refseq:XP_005277458.1|refseq:XP_006711555.1|refseq:XP_011507915.1|refseq:XP_011508212.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:vLTq1R+bG9wT6RNToV/a6lRGpQ0272561 rogid:4pAq3FBvosP3U/y/iw/ixx+QPcM9606 rigid:KvCgcQYs8exwZmnc59Vw33LiyoQ false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84733 uniprotkb:O60779 intact:EBI-22303635|ensemblbacteria:AAC68323 intact:EBI-3941998|uniprotkb:Q8WV87|uniprotkb:Q9UBL7|uniprotkb:Q9UN31|uniprotkb:Q9UN43|uniprotkb:B2R9H0|uniprotkb:Q9UKJ2|uniprotkb:B4E1X4|ensembl:ENSP00000236137 psi-mi:o84733_chltr(display_long)|uniprotkb:CT_728(locus name) psi-mi:s19a2_human(display_long)|uniprotkb:SLC19A2(gene name)|psi-mi:SLC19A2(display_short)|uniprotkb:THT1(gene name synonym)|uniprotkb:TRMA(gene name synonym)|uniprotkb:Solute carrier family 19 member 2(gene name synonym)|uniprotkb:Thiamine carrier 1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303646|imex:IM-27647-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68323(transcript)|ensemblbacteria:CT_728(gene)|go:"GO:0005384"(manganese ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030026"(cellular manganese ion homeostasis)|mint:O84733|refseq:NP_220247.1|refseq:WP_009872105.1|interpro:IPR008217(Protein of unknown function DUF125, transmembrane) interpro:IPR002666(Reduced folate carrier)|interpro:IPR028338|ensembl:ENSG00000117479(gene)|interpro:IPR036259|mint:O60779|ensembl:ENST00000236137(transcript)|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-196819|go:"GO:0008517"(folic acid transmembrane transporter activity)|go:"GO:0015234"(thiamine transmembrane transporter activity)|go:"GO:0015888"(thiamine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042723"(thiamine-containing compound metabolic process)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071934"(thiamine transmembrane transport)|refseq:NP_008927.1|refseq:NP_001306596.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:vLTq1R+bG9wT6RNToV/a6lRGpQ0272561 rogid:jaxPhDzyD6VTkLBvxtw/nCixzAE9606 rigid:KvCgcQYs8exwZmnc59Vw33LiyoQ false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84733 uniprotkb:Q96AA3 intact:EBI-22303635|ensemblbacteria:AAC68323 intact:EBI-6269616|ensembl:ENSP00000296292|uniprotkb:Q96J03 psi-mi:o84733_chltr(display_long)|uniprotkb:CT_728(locus name) psi-mi:rft1_human(display_long)|uniprotkb:RFT1(gene name)|psi-mi:RFT1(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303646|imex:IM-27647-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68323(transcript)|ensemblbacteria:CT_728(gene)|go:"GO:0005384"(manganese ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030026"(cellular manganese ion homeostasis)|mint:O84733|refseq:NP_220247.1|refseq:WP_009872105.1|interpro:IPR008217(Protein of unknown function DUF125, transmembrane) ensembl:ENSG00000163933(gene)|ensembl:ENST00000296292(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034202"(glycolipid floppase activity)|go:"GO:0034203"(glycolipid translocation)|interpro:IPR007594(RFT1)|mint:Q96AA3|reactome:R-HSA-446193|reactome:R-HSA-4570571|refseq:NP_443091.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:vLTq1R+bG9wT6RNToV/a6lRGpQ0272561 rogid:off+uN6MYDiLT5q1oh7G2sd6RXw9606 rigid:KvCgcQYs8exwZmnc59Vw33LiyoQ false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84819 uniprotkb:Q9NYJ1 intact:EBI-22303654|ensemblbacteria:AAC68409 intact:EBI-22303661|ensembl:ENSP00000347919|ensembl:ENSP00000437772|ensembl:ENSP00000443795|uniprotkb:B2RAA0|uniprotkb:Q69YU4 psi-mi:o84819_chltr(display_long)|uniprotkb:CT_813(locus name) psi-mi:coa4_human(display_long)|uniprotkb:COA4(gene name)|psi-mi:COA4(display_short)|uniprotkb:CHCHD8(gene name synonym)|uniprotkb:E2IG2(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 8(gene name synonym)|uniprotkb:E2-induced gene 2 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303686|imex:IM-27647-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68409(transcript)|ensemblbacteria:CT_813(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84819|refseq:NP_220333.1|refseq:WP_010725353.1 ensembl:ENSG00000181924(gene)|ensembl:ENST00000355693(transcript)|ensembl:ENST00000537289(transcript)|ensembl:ENST00000545127(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR039870|mint:Q9NYJ1|reactome:R-HSA-1268020|refseq:NP_057649.2|refseq:XP_016873372.1|refseq:XP_016873373.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:h+iT8ll8HZRbGJFygUbuA0mwjoE272561 rogid:L1PGDFR+DvWHCwqfW6bL3atHvVs9606 rigid:LLfbFXeEQ2gBj+ErBRHlMhfTbYE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84819 uniprotkb:P60510 intact:EBI-22303654|ensemblbacteria:AAC68409 intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995 psi-mi:o84819_chltr(display_long)|uniprotkb:CT_813(locus name) psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303686|imex:IM-27647-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68409(transcript)|ensemblbacteria:CT_813(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84819|refseq:NP_220333.1|refseq:WP_010725353.1 refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:h+iT8ll8HZRbGJFygUbuA0mwjoE272561 rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606 rigid:LLfbFXeEQ2gBj+ErBRHlMhfTbYE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84819 uniprotkb:Q9Y6V7 intact:EBI-22303654|ensemblbacteria:AAC68409 intact:EBI-719274|uniprotkb:Q53FJ1|uniprotkb:E7ENA0|uniprotkb:Q9BVQ8|ensembl:ENSP00000247003 psi-mi:o84819_chltr(display_long)|uniprotkb:CT_813(locus name) psi-mi:ddx49_human(display_long)|uniprotkb:DEAD box protein 49(gene name synonym)|uniprotkb:DDX49(gene name)|psi-mi:DDX49(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303686|imex:IM-27647-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68409(transcript)|ensemblbacteria:CT_813(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84819|refseq:NP_220333.1|refseq:WP_010725353.1 refseq:NP_061943.2|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|ensembl:ENST00000247003(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR014001(DEAD-like helicase, N-terminal)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006364"(rRNA processing)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9Y6V7|go:"GO:0030307"(positive regulation of cell growth)|reactome:R-HSA-6790901|reactome:R-HSA-6791226|go:"GO:0044357"(regulation of rRNA stability)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|ensembl:ENSG00000105671(gene) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:h+iT8ll8HZRbGJFygUbuA0mwjoE272561 rogid:Yfej1zXpPTue3eewQcR5OpNILeM9606 rigid:LLfbFXeEQ2gBj+ErBRHlMhfTbYE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84819 uniprotkb:Q6L8Q7 intact:EBI-22303654|ensemblbacteria:AAC68409 intact:EBI-2515865|ensembl:ENSP00000309142|uniprotkb:Q8IYU3|uniprotkb:Q8NDU2|uniprotkb:Q8TE78|uniprotkb:B4DTU8 psi-mi:o84819_chltr(display_long)|uniprotkb:CT_813(locus name) psi-mi:pde12_human(display_long)|uniprotkb:PDE12(gene name)|psi-mi:PDE12(display_short)|uniprotkb:Mitochondrial deadenylase(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303686|imex:IM-27647-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68409(transcript)|ensemblbacteria:CT_813(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84819|refseq:NP_220333.1|refseq:WP_010725353.1 ensembl:ENST00000311180(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000958"(mitochondrial mRNA catabolic process)|go:"GO:0004527"(exonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0034611"(oligoribonucleotidase activity)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0044528"(regulation of mitochondrial mRNA stability)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0090324"(negative regulation of oxidative phosphorylation)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|ensembl:ENSG00000174840(gene)|interpro:IPR036691|mint:Q6L8Q7|rcsb pdb:4Z0V|rcsb pdb:4Z2B|rcsb pdb:4ZKF|reactome:R-HSA-8983711|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|refseq:NP_808881.3 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:h+iT8ll8HZRbGJFygUbuA0mwjoE272561 rogid:P2ALFhSP4Qnqnd08vmkOcVoXe/I9606 rigid:LLfbFXeEQ2gBj+ErBRHlMhfTbYE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84819 uniprotkb:Q8N3F8 intact:EBI-22303654|ensemblbacteria:AAC68409 intact:EBI-1056885|uniprotkb:Q5TI16|uniprotkb:Q7RTP5|uniprotkb:Q8N3N8|uniprotkb:Q9BVL9|uniprotkb:Q9BY92|uniprotkb:Q9UH43|uniprotkb:Q9UH44|uniprotkb:Q9UH45|ensembl:ENSP00000215957 psi-mi:o84819_chltr(display_long)|uniprotkb:CT_813(locus name) psi-mi:milk1_human(display_long)|uniprotkb:MICALL1(gene name)|psi-mi:MICALL1(display_short)|uniprotkb:KIAA1668(gene name synonym)|uniprotkb:MIRAB13(gene name synonym)|uniprotkb:Molecule interacting with Rab13(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303686|imex:IM-27647-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68409(transcript)|ensemblbacteria:CT_813(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84819|refseq:NP_220333.1|refseq:WP_010725353.1 refseq:NP_203744.1|ensembl:ENSP00000215957|ensembl:ENSG00000100139(gene)|ensembl:ENST00000215957(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032458"(slow endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR022735|interpro:IPR028563|interpro:IPR036872|mint:Q8N3F8|rcsb pdb:2KSP|go:"GO:0045296"(cadherin binding) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:h+iT8ll8HZRbGJFygUbuA0mwjoE272561 rogid:G64P9EtjEfLIVLYkb+w3vCWaT0w9606 rigid:LLfbFXeEQ2gBj+ErBRHlMhfTbYE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84819 uniprotkb:Q96J02 intact:EBI-22303654|ensemblbacteria:AAC68409 intact:EBI-1564678|uniprotkb:O43584|uniprotkb:Q5TEL0|uniprotkb:Q96F66|uniprotkb:Q9BY75|uniprotkb:Q9H451|uniprotkb:Q9H4U5|uniprotkb:A6NEW4|uniprotkb:Q5QP37|uniprotkb:E1P5P3|uniprotkb:B4E234|uniprotkb:F5H217|ensembl:ENSP00000262650|ensembl:ENSP00000499786 psi-mi:o84819_chltr(display_long)|uniprotkb:CT_813(locus name) psi-mi:itch_human(display_long)|uniprotkb:HECT-type E3 ubiquitin transferase Itchy homolog(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 4(gene name synonym)|uniprotkb:NFE2-associated polypeptide 1(gene name synonym)|uniprotkb:ITCH(gene name)|psi-mi:ITCH(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303686|imex:IM-27647-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68409(transcript)|ensemblbacteria:CT_813(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84819|refseq:NP_220333.1|refseq:WP_010725353.1 refseq:NP_001311126.1|refseq:NP_113671.3|refseq:NP_001244066.1|refseq:NP_001311127.1|refseq:NP_001244067.1|refseq:XP_016883578.1|refseq:XP_016883580.1|dip:DIP-29849N|ensembl:ENSG00000078747(gene)|ensembl:ENST00000262650(transcript)|ensembl:ENST00000665346(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045236"(CXCR chemokine receptor binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046642"(negative regulation of alpha-beta T cell proliferation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090085"(regulation of protein deubiquitination)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:2000646"(positive regulation of receptor catabolic process)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:Q96J02|rcsb pdb:2DMV|rcsb pdb:2KYK|rcsb pdb:2NQ3|rcsb pdb:2P4R|rcsb pdb:2YSF|rcsb pdb:3TUG|rcsb pdb:4ROF|rcsb pdb:5C7M|rcsb pdb:5CQ2|rcsb pdb:5DWS|rcsb pdb:5DZD|rcsb pdb:5SXP|reactome:R-HSA-1253288|reactome:R-HSA-168638|reactome:R-HSA-2122948|reactome:R-HSA-5610780|reactome:R-HSA-5632684|reactome:R-HSA-8939236|reactome:R-HSA-936440|reactome:R-HSA-983168 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:h+iT8ll8HZRbGJFygUbuA0mwjoE272561 rogid:JyySOfI+ZHOI1mvdxWDGN6njgCY9606 rigid:LLfbFXeEQ2gBj+ErBRHlMhfTbYE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84819 uniprotkb:P43246 intact:EBI-22303654|ensemblbacteria:AAC68409 intact:EBI-355888|uniprotkb:O75488|uniprotkb:B4E2Z2|ensembl:ENSP00000233146 psi-mi:o84819_chltr(display_long)|uniprotkb:CT_813(locus name) psi-mi:msh2_human(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:MutS protein homolog 2(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303686|imex:IM-27647-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68409(transcript)|ensemblbacteria:CT_813(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84819|refseq:NP_220333.1|refseq:WP_010725353.1 refseq:NP_000242.1|refseq:NP_001245210.1|ensembl:ENSG00000095002(gene)|ensembl:ENST00000233146(transcript)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002204"(somatic recombination of immunoglobulin genes involved in immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007281"(germ cell development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008584"(male gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010224"(response to UV-B)|go:"GO:0016020"(membrane)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|mint:P43246|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:3THW|rcsb pdb:3THX|rcsb pdb:3THY|rcsb pdb:3THZ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5632927|reactome:R-HSA-5632928|reactome:R-HSA-5632968|reactome:R-HSA-6796648|dip:DIP-35054N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:h+iT8ll8HZRbGJFygUbuA0mwjoE272561 rogid:7vcyX6SkXRo28b+4b+JBg7j/ec89606 rigid:LLfbFXeEQ2gBj+ErBRHlMhfTbYE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84819 uniprotkb:Q8TF05 intact:EBI-22303654|ensemblbacteria:AAC68409 intact:EBI-1056262|uniprotkb:Q99774|uniprotkb:Q9UNQ7|ensembl:ENSP00000383402 psi-mi:o84819_chltr(display_long)|uniprotkb:CT_813(locus name) psi-mi:pp4r1_human(display_long)|uniprotkb:PPP4R1(gene name)|psi-mi:PPP4R1(display_short)|uniprotkb:MEG1(gene name synonym)|uniprotkb:PP4R1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303686|imex:IM-27647-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68409(transcript)|ensemblbacteria:CT_813(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84819|refseq:NP_220333.1|refseq:WP_010725353.1 refseq:NP_001035847.1|refseq:NP_005125.1|ensembl:ENSG00000154845(gene)|ensembl:ENST00000400556(transcript)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030289"(protein phosphatase 4 complex)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031087|interpro:IPR033461|mint:Q8TF05 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:h+iT8ll8HZRbGJFygUbuA0mwjoE272561 rogid:c7WdQEzkeS6LDpC2GD9czxBdWj09606 rigid:LLfbFXeEQ2gBj+ErBRHlMhfTbYE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84819 uniprotkb:O00267 intact:EBI-22303654|ensemblbacteria:AAC68409 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 psi-mi:o84819_chltr(display_long)|uniprotkb:CT_813(locus name) psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303686|imex:IM-27647-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68409(transcript)|ensemblbacteria:CT_813(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84819|refseq:NP_220333.1|refseq:WP_010725353.1 refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:h+iT8ll8HZRbGJFygUbuA0mwjoE272561 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rigid:LLfbFXeEQ2gBj+ErBRHlMhfTbYE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84819 uniprotkb:P52701 intact:EBI-22303654|ensemblbacteria:AAC68409 intact:EBI-395529|uniprotkb:O43706|uniprotkb:O43917|uniprotkb:Q8TCX4|uniprotkb:Q9BTB5|ensembl:ENSP00000234420|uniprotkb:B4DF41|uniprotkb:B4E3I4|uniprotkb:F5H2F9 psi-mi:o84819_chltr(display_long)|uniprotkb:CT_813(locus name) psi-mi:msh6_human(display_long)|uniprotkb:MSH6(gene name)|psi-mi:MSH6(display_short)|uniprotkb:MutS-alpha 160 kDa subunit(gene name synonym)|uniprotkb:G/T mismatch-binding protein(gene name synonym)|uniprotkb:GTBP(gene name synonym)|uniprotkb:MutS protein homolog 6(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303686|imex:IM-27647-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68409(transcript)|ensemblbacteria:CT_813(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84819|refseq:NP_220333.1|refseq:WP_010725353.1 refseq:NP_000170.1|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009411"(response to UV)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|mint:P52701|rcsb pdb:2GFU|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:6OQM|reactome:R-HSA-5358565|reactome:R-HSA-5632928|reactome:R-HSA-5632968|ensembl:ENSG00000116062(gene)|ensembl:ENST00000234420(transcript)|refseq:NP_001268421.1|refseq:NP_001268422.1|refseq:NP_001268423.1|dip:DIP-32972N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:h+iT8ll8HZRbGJFygUbuA0mwjoE272561 rogid:YPpiWmh4fSjXapWgA/rXbMrLAGg9606 rigid:LLfbFXeEQ2gBj+ErBRHlMhfTbYE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84820 uniprotkb:Q9BW61 intact:EBI-22303701|ensemblbacteria:AAC68410 intact:EBI-2510241|ensembl:ENSP00000352928|ensembl:ENSP00000472171|ensembl:ENSP00000473086 psi-mi:o84820_chltr(display_long)|uniprotkb:CT_814(locus name) psi-mi:dda1_human(display_long)|uniprotkb:DDA1(gene name)|psi-mi:DDA1(display_short)|uniprotkb:C19orf58(gene name synonym)|uniprotkb:PCIA1(gene name synonym)|uniprotkb:Placenta cross-immune reaction antigen 1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303708|imex:IM-27647-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68410(transcript)|ensemblbacteria:CT_814(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84820|refseq:NP_220334.1|refseq:WP_010725354.1 ensembl:ENSG00000130311(gene)|ensembl:ENST00000359866(transcript)|ensembl:ENST00000593466(transcript)|ensembl:ENST00000596582(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR018276|interpro:IPR033575|mint:Q9BW61|rcsb pdb:6DSZ|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6SJ7|rcsb pdb:6UD7|rcsb pdb:6UE5|reactome:R-HSA-8951664|refseq:NP_076955.1|dip:DIP-53527N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:vK/WLNMoij0Z894SiWg1VaF2vHU272561 rogid:yD3tRVKVhirdHUj58DCTphW7ZYs9606 rigid:hVcEJUy4gtL1DEOT/9gHN0b6zkY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84820 uniprotkb:O43164 intact:EBI-22303701|ensemblbacteria:AAC68410 intact:EBI-1996038|uniprotkb:D3DSZ5|uniprotkb:Q68D49|uniprotkb:Q8N1G5|uniprotkb:A8K6U4|ensembl:ENSP00000354775|ensembl:ENSP00000355284 psi-mi:o84820_chltr(display_long)|uniprotkb:CT_814(locus name) psi-mi:pja2_human(display_long)|uniprotkb:PJA2(gene name)|psi-mi:PJA2(display_short)|uniprotkb:KIAA0438(gene name synonym)|uniprotkb:RNF131(gene name synonym)|uniprotkb:RING finger protein 131(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Praja-2(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303708|imex:IM-27647-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68410(transcript)|ensemblbacteria:CT_814(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84820|refseq:NP_220334.1|refseq:WP_010725354.1 refseq:NP_055634.3|refseq:XP_016865588.1|ensembl:ENSG00000198961(gene)|ensembl:ENST00000361189(transcript)|ensembl:ENST00000361557(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007616"(long-term memory)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035329"(hippo signaling)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR030639|mint:O43164|reactome:R-HSA-983168|dip:DIP-47040N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:vK/WLNMoij0Z894SiWg1VaF2vHU272561 rogid:z0OkXLozXymqwyF+xQR+PFa+bQI9606 rigid:hVcEJUy4gtL1DEOT/9gHN0b6zkY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84820 uniprotkb:Q9Y4B6 intact:EBI-22303701|ensemblbacteria:AAC68410 intact:EBI-1996353|uniprotkb:Q2YD74|uniprotkb:Q8TBD9|uniprotkb:Q9HCA1|uniprotkb:Q9UG37|intact:EBI-2559078|intact:EBI-28988191|ensembl:ENSP00000393183|ensembl:ENSP00000506880 psi-mi:o84820_chltr(display_long)|uniprotkb:CT_814(locus name) psi-mi:dcaf1_human(display_long)|uniprotkb:DCAF1(gene name)|psi-mi:DCAF1(display_short)|uniprotkb:HIV-1 Vpr-binding protein(gene name synonym)|uniprotkb:KIAA0800(gene name synonym)|uniprotkb:RIP(gene name synonym)|uniprotkb:Serine/threonine-protein kinase VPRBP(gene name synonym)|uniprotkb:VPRBP(gene name synonym)|uniprotkb:Vpr-interacting protein(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303708|imex:IM-27647-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68410(transcript)|ensemblbacteria:CT_814(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84820|refseq:NP_220334.1|refseq:WP_010725354.1 refseq:NP_001165375.1|refseq:NP_055518.1|refseq:XP_011532575.1|refseq:XP_011532576.1|refseq:XP_011532577.1|refseq:XP_011532578.1|refseq:XP_011532579.1|refseq:XP_016863035.1|refseq:XP_016863036.1|refseq:XP_016863037.1|refseq:XP_016863038.1|refseq:XP_016863039.1|ensembl:ENST00000335891|ensembl:ENSP00000338857|ensembl:ENSP00000393183|ensembl:ENST00000504652|ensembl:ENSP00000421724|ensembl:ENSP00000506880|ensembl:ENSG00000145041(gene)|ensembl:ENST00000423656(transcript)|ensembl:ENST00000684031(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990244"("histone kinase activity (H2A-T120 specific)")|go:"GO:1990245"(histone H2A-T120 phosphorylation)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033270|interpro:IPR036322|mint:Q9Y4B6|rcsb pdb:3WA0|rcsb pdb:4CC9|rcsb pdb:4P7I|rcsb pdb:4PXW|rcsb pdb:4Z8L|rcsb pdb:5AJA|rcsb pdb:5JK7|rcsb pdb:6N45|reactome:R-HSA-983168|refseq:XP_005276810.1|refseq:XP_005276812.1|dip:DIP-47048N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:vK/WLNMoij0Z894SiWg1VaF2vHU272561 rogid:qs3qG0MM135EE/DjC1S/gCLRFhc9606 rigid:hVcEJUy4gtL1DEOT/9gHN0b6zkY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84826 uniprotkb:Q13505 intact:EBI-22303716|ensemblbacteria:AAC68416 intact:EBI-1052588|uniprotkb:B1AVR9|uniprotkb:B1AVS0|uniprotkb:B2R9P4|uniprotkb:Q9BUU3|uniprotkb:A0A0A0MRK6|ensembl:ENSP00000357360 psi-mi:y819_chltr(display_long)|uniprotkb:CT_819(locus name) psi-mi:mtx1_human(display_long)|uniprotkb:MTX1(gene name)|psi-mi:MTX1(display_short)|uniprotkb:MTX(gene name synonym)|uniprotkb:MTXN(gene name synonym)|uniprotkb:Mitochondrial outer membrane import complex protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303725|imex:IM-27647-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68416(transcript)|ensemblbacteria:CT_819(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:O84826|refseq:NP_220340.1|refseq:WP_009872956.1|interpro:IPR006214(Protein of unknown function UPF0005) refseq:NP_002446.3|refseq:NP_942584.2|ensembl:ENSG00000173171(gene)|ensembl:ENST00000368376(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0007595"(lactation)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140275"(MIB complex)|interpro:IPR019564|interpro:IPR033468|interpro:IPR036282|interpro:IPR040079|mint:Q13505|reactome:R-HSA-1268020|reactome:R-HSA-8949613|reactome:R-HSA-9013404 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:ICKqu0SV5jIHm0iWAZG30pvCx3k272561 rogid:LoRdRoXuGOFmrPBEt324uUHgKos9606 rigid:jeZ8eM+fiRf+8PpUMbyM7zfk0gg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84826 uniprotkb:O15067 intact:EBI-22303716|ensemblbacteria:AAC68416 intact:EBI-1052653|uniprotkb:A6H8V8|ensembl:ENSP00000313490 psi-mi:y819_chltr(display_long)|uniprotkb:CT_819(locus name) psi-mi:pur4_human(display_long)|uniprotkb:Formylglycinamide ribotide amidotransferase(gene name synonym)|uniprotkb:PFAS(gene name)|psi-mi:PFAS(display_short)|uniprotkb:KIAA0361(gene name synonym)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303725|imex:IM-27647-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68416(transcript)|ensemblbacteria:CT_819(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:O84826|refseq:NP_220340.1|refseq:WP_009872956.1|interpro:IPR006214(Protein of unknown function UPF0005) refseq:NP_036525.1|ensembl:ENSG00000178921(gene)|ensembl:ENST00000314666(transcript)|go:"GO:0004642"(phosphoribosylformylglycinamidine synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0009168"(purine ribonucleoside monophosphate biosynthetic process)|go:"GO:0042493"|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097065"(anterior head development)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR029062|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR040707|interpro:IPR041609|mint:O15067|reactome:R-HSA-73817 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:ICKqu0SV5jIHm0iWAZG30pvCx3k272561 rogid:e52AyHjHUrLjnoJP+rInkcvfGJk9606 rigid:jeZ8eM+fiRf+8PpUMbyM7zfk0gg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84826 uniprotkb:A1L188 intact:EBI-22303716|ensemblbacteria:AAC68416 intact:EBI-20593474|ensembl:ENSP00000400184 psi-mi:y819_chltr(display_long)|uniprotkb:CT_819(locus name) psi-mi:nduf8_human(display_long)|uniprotkb:NDUFAF8(gene name)|psi-mi:NDUFAF8(display_short)|uniprotkb:C17orf89(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303725|imex:IM-27647-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68416(transcript)|ensemblbacteria:CT_819(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:O84826|refseq:NP_220340.1|refseq:WP_009872956.1|interpro:IPR006214(Protein of unknown function UPF0005) refseq:NP_001079990.1|ensembl:ENSG00000224877(gene)|ensembl:ENST00000431388(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR034595|mint:A1L188 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:ICKqu0SV5jIHm0iWAZG30pvCx3k272561 rogid:S/mahr2flAFENqydZrw3d9WyQqM9606 rigid:jeZ8eM+fiRf+8PpUMbyM7zfk0gg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84826 uniprotkb:Q8N5G0 intact:EBI-22303716|ensemblbacteria:AAC68416 intact:EBI-6570855|ensembl:ENSP00000427407|uniprotkb:C9JYT8|uniprotkb:Q9BRT5 psi-mi:y819_chltr(display_long)|uniprotkb:CT_819(locus name) psi-mi:sim20_human(display_long)|uniprotkb:SMIM20(gene name)|psi-mi:SMIM20(display_short)|uniprotkb:C4orf52(gene name synonym)|uniprotkb:MITRAC7(gene name synonym)|uniprotkb:Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 7 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303725|imex:IM-27647-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68416(transcript)|ensemblbacteria:CT_819(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:O84826|refseq:NP_220340.1|refseq:WP_009872956.1|interpro:IPR006214(Protein of unknown function UPF0005) ensembl:ENSG00000250317(gene)|ensembl:ENST00000506197(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR027917|mint:Q8N5G0|refseq:NP_001138904.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:ICKqu0SV5jIHm0iWAZG30pvCx3k272561 rogid:yqRjpvlmOpU7RfsXACpQ7ytSFZE9606 rigid:jeZ8eM+fiRf+8PpUMbyM7zfk0gg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84826 uniprotkb:Q5TEU4 intact:EBI-22303716|ensemblbacteria:AAC68416 intact:EBI-10762958|uniprotkb:A8K166|uniprotkb:Q6GPH3|uniprotkb:Q9H6F4|ensembl:ENSP00000367346 psi-mi:y819_chltr(display_long)|uniprotkb:CT_819(locus name) psi-mi:nduf5_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5(gene name synonym)|uniprotkb:Putative methyltransferase NDUFAF5(gene name synonym)|uniprotkb:NDUFAF5(gene name)|psi-mi:NDUFAF5(display_short)|uniprotkb:C20orf7(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303725|imex:IM-27647-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68416(transcript)|ensemblbacteria:CT_819(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:O84826|refseq:NP_220340.1|refseq:WP_009872956.1|interpro:IPR006214(Protein of unknown function UPF0005) refseq:NP_001034464.1|refseq:NP_077025.2|ensembl:ENSG00000101247(gene)|ensembl:ENST00000378106(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030961"(peptidyl-arginine hydroxylation)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0032259"(methylation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|mint:Q5TEU4|reactome:R-HSA-6799198 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:ICKqu0SV5jIHm0iWAZG30pvCx3k272561 rogid:BC4jrAunVf7T4Cbrr/sZVFnkrfA9606 rigid:jeZ8eM+fiRf+8PpUMbyM7zfk0gg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84853 uniprotkb:O76024 intact:EBI-22303735|ensemblbacteria:AAC68443 intact:EBI-720609|uniprotkb:Q8N6I3|uniprotkb:Q9UNW6|uniprotkb:B2R797|uniprotkb:D3DVT1|ensembl:ENSP00000226760|ensembl:ENSP00000423337|ensembl:ENSP00000506978 psi-mi:o84853_chltr(display_long)|uniprotkb:CT_846(locus name) psi-mi:wfs1_human(display_long)|uniprotkb:WFS1(gene name)|psi-mi:WFS1(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303742|imex:IM-27647-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68443(transcript)|ensemblbacteria:CT_846(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84853|refseq:NP_220367.1|refseq:WP_009872233.1 go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|go:"GO:1903892"(negative regulation of ATF6-mediated unfolded protein response)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR026208|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050877"(nervous system process)|go:"GO:0051117"(ATPase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0070628"(proteasome binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR026209|refseq:NP_001139325.1|refseq:NP_005996.2|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030141"(secretory granule)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031016"(pancreas development)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENSG00000109501(gene)|ensembl:ENST00000226760(transcript)|ensembl:ENST00000503569(transcript)|ensembl:ENST00000684087(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001822"(kidney development)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|reactome:R-HSA-381038|reactome:R-HSA-381426|reactome:R-HSA-8957275|mint:O76024 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:E5HBJR0LBremFNwkwQd/1CHiNnc272561 rogid:bt4NKJUKyrQeJ8emdvrT3sg0Rf49606 rigid:iege/AERe27gbA4lIWnfcRrNjD0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84853 uniprotkb:Q8WVP7 intact:EBI-22303735|ensemblbacteria:AAC68443 intact:EBI-6138627|uniprotkb:A4D242|uniprotkb:Q8N3E3|uniprotkb:Q96QZ5|uniprotkb:Q9H5N0|uniprotkb:Q9HAG9|uniprotkb:Q9UDN5|uniprotkb:Q9Y6U2|ensembl:ENSP00000326604 psi-mi:o84853_chltr(display_long)|uniprotkb:CT_846(locus name) psi-mi:lmbr1_human(display_long)|uniprotkb:LMBR1(gene name)|psi-mi:LMBR1(display_short)|uniprotkb:C7orf2(gene name synonym)|uniprotkb:DIF14(gene name synonym)|uniprotkb:Differentiation-related gene 14 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303742|imex:IM-27647-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68443(transcript)|ensemblbacteria:CT_846(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84853|refseq:NP_220367.1|refseq:WP_009872233.1 refseq:NP_071903.2|refseq:XP_016867996.1|ensembl:ENSG00000105983(gene)|ensembl:ENST00000353442(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0042733"(embryonic digit morphogenesis)|interpro:IPR006876(LMBR1-like conserved region)|interpro:IPR008075(Lipocalin-1 receptor)|mint:Q8WVP7 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:E5HBJR0LBremFNwkwQd/1CHiNnc272561 rogid:a5rq7+LN7TI2Niu8fC9MeRARQvU9606 rigid:iege/AERe27gbA4lIWnfcRrNjD0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CI27 uniprotkb:Q08209 intact:EBI-22303749|ensemblbacteria:AAC67710|uniprotkb:O84121|uniprotkb:Q99Q56|uniprotkb:Q9AM94|uniprotkb:Q9AMA7|uniprotkb:Q9AMA8|uniprotkb:Q9AMA9|uniprotkb:Q9AMB0|uniprotkb:Q9AMB1|uniprotkb:Q9F7K9|uniprotkb:Q9RFX7 intact:EBI-352922|uniprotkb:Q8TAW9|uniprotkb:A8K3B7|uniprotkb:B5BUA2|uniprotkb:A1A441|uniprotkb:A8W6Z7|ensembl:ENSP00000378323|uniprotkb:A8W6Z8 psi-mi:inca_chltr(display_long)|uniprotkb:incA(gene name)|psi-mi:incA(display_short)|uniprotkb:CT_119(locus name) psi-mi:pp2ba_human(display_long)|uniprotkb:PPP3CA(gene name)|psi-mi:PPP3CA(display_short)|uniprotkb:CALNA(gene name synonym)|uniprotkb:CNA(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin A subunit alpha isoform(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303771|imex:IM-27647-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67710(transcript)|ensemblbacteria:CT_119(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:6E6A|rcsb pdb:6E7E|go:"GO:0005576"(extracellular region)|mint:P0CI27|refseq:NP_219622.1|refseq:WP_009871466.1 go:"GO:1905205"(positive regulation of connective tissue replacement)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|mint:Q08209|rcsb pdb:1AUI|rcsb pdb:1M63|rcsb pdb:1MF8|rcsb pdb:2JOG|rcsb pdb:2JZI|rcsb pdb:2P6B|rcsb pdb:2R28|rcsb pdb:2W73|rcsb pdb:3LL8|rcsb pdb:4F0Z|rcsb pdb:4Q5U|rcsb pdb:5C1V|rcsb pdb:5SVE|rcsb pdb:6NUC|rcsb pdb:6NUF|rcsb pdb:6NUU|rcsb pdb:6UUQ|reactome:R-HSA-180024|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-5607763|reactome:R-HSA-2025928|refseq:NP_000935.1|refseq:NP_001124163.1|refseq:NP_001124164.1|go:"GO:0043197"(dendritic spine)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903244"(positive regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000138814(gene)|ensembl:ENST00000394854(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0036057"(slit diaphragm)|go:"GO:0042060"(wound healing)|go:"GO:0042110"(T cell activation)|go:"GO:0042383"(sarcolemma)|dip:DIP-6095N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:ccmWavz7ZW1HZZFFu1T5BVIQLVs272561 rogid:kYtl+Yk39rbcDp5vIjH8WLsZysU9606 rigid:/Es0wNLUuiX+juWtRxnYT36AFJM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CI27 uniprotkb:Q5SW79 intact:EBI-22303749|ensemblbacteria:AAC67710|uniprotkb:O84121|uniprotkb:Q99Q56|uniprotkb:Q9AM94|uniprotkb:Q9AMA7|uniprotkb:Q9AMA8|uniprotkb:Q9AMA9|uniprotkb:Q9AMB0|uniprotkb:Q9AMB1|uniprotkb:Q9F7K9|uniprotkb:Q9RFX7 intact:EBI-1104799|uniprotkb:O75058|uniprotkb:Q5SW77|uniprotkb:Q5SW78|uniprotkb:Q7LGA9|uniprotkb:Q86W31|uniprotkb:Q9UQ08|uniprotkb:Q9UQ09|intact:EBI-2559293|intact:EBI-2554822|ensembl:ENSP00000355500|ensembl:ENSP00000483344 psi-mi:inca_chltr(display_long)|uniprotkb:incA(gene name)|psi-mi:incA(display_short)|uniprotkb:CT_119(locus name) psi-mi:ce170_human(display_long)|uniprotkb:CEP170(gene name)|psi-mi:CEP170(display_short)|uniprotkb:FAM68A(gene name synonym)|uniprotkb:KAB(gene name synonym)|uniprotkb:KIAA0470(gene name synonym)|uniprotkb:KARP-1-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303771|imex:IM-27647-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67710(transcript)|ensemblbacteria:CT_119(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:6E6A|rcsb pdb:6E7E|go:"GO:0005576"(extracellular region)|mint:P0CI27|refseq:NP_219622.1|refseq:WP_009871466.1 refseq:NP_001035863.1|refseq:NP_001035864.1|refseq:NP_055627.2|ensembl:ENSG00000143702(gene)|ensembl:ENSG00000276725(gene)|ensembl:ENST00000366542(transcript)|ensembl:ENST00000612450(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR026644|interpro:IPR029300|mint:Q5SW79|rcsb pdb:4JON|refseq:XP_016858425.1|dip:DIP-37594N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:ccmWavz7ZW1HZZFFu1T5BVIQLVs272561 rogid:gEJsUZqeO9zpm94iMzIAUvsUbqc9606 rigid:/Es0wNLUuiX+juWtRxnYT36AFJM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q86XE0 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-8099743|uniprotkb:Q8IW53|intact:MINT-8163285|intact:MINT-6940005|uniprotkb:Q96NG4|ensembl:ENSP00000310620 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:snx32_human(display_long)|uniprotkb:Sorting nexin-6B(gene name synonym)|uniprotkb:SNX32(gene name)|psi-mi:SNX32(display_short)|uniprotkb:SNX6B(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303794|imex:IM-27647-75 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_689973.2|ensembl:ENSG00000172803(gene)|ensembl:ENST00000308342(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR036871|mint:Q86XE0|rcsb pdb:6E8R - - function:May be involved in several stages of intracellular trafficking figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:I0+rJkFVm8v1eM51FMdsDBEFACc9606 rigid:koGrMfyrJ7DbrHfWOvpv0qJbyRc false binding-associated region:101-132|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q86TI2 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-7475352|uniprotkb:Q8N2J7|uniprotkb:Q1ZZB8|uniprotkb:O75273|uniprotkb:Q8WXD8|uniprotkb:Q9BVR3|uniprotkb:Q6AI37|uniprotkb:Q8N3F5|uniprotkb:Q96NT8|uniprotkb:Q6UAL0|intact:MINT-4535936|uniprotkb:O75868|uniprotkb:Q6ZMT2|uniprotkb:Q6ZNJ5|ensembl:ENSP00000469603 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:dpp9_human(display_long)|uniprotkb:DPP9(gene name)|psi-mi:DPP9(display_short)|uniprotkb:DPRP2(gene name synonym)|uniprotkb:Dipeptidyl peptidase IV-related protein 2(gene name synonym)|uniprotkb:Dipeptidyl peptidase IX(gene name synonym)|uniprotkb:Dipeptidyl peptidase-like protein 9(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303794|imex:IM-27647-75 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:XP_011526710.1|refseq:XP_011526712.1|refseq:NP_631898.3|refseq:XP_005259730.1|ensembl:ENSG00000142002(gene)|ensembl:ENST00000598800(transcript)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008239"(dipeptidyl-peptidase activity)|go:"GO:0031252"(cell leading edge)|go:"GO:0042802"(identical protein binding)|interpro:IPR001375(Peptidase S9, prolyl oligopeptidase active site region)|interpro:IPR002469(Peptidase S9B, dipeptidylpeptidase IV N-terminal)|interpro:IPR029058|mint:Q86TI2|rcsb pdb:6EOQ|rcsb pdb:6EOR|rcsb pdb:6QZV|rcsb pdb:6X6A|rcsb pdb:6X6C|rcsb pdb:7A3F|rcsb pdb:7JKQ|rcsb pdb:7JN7 - - comment:mint|function:Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2 figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:m3rJ6BPsdQqnesPiTY9vclr5hE49606 rigid:koGrMfyrJ7DbrHfWOvpv0qJbyRc false binding-associated region:101-132|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q13888 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-1565170|uniprotkb:Q15570|uniprotkb:Q15571|uniprotkb:Q9BS41|ensembl:ENSP00000274400|ensembl:ENSP00000328901|ensembl:ENSP00000477954|ensembl:ENSP00000479262|ensembl:ENSP00000480548|ensembl:ENSP00000486014 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:tf2h2_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 2(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p44 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 44 kDa subunit(gene name synonym)|uniprotkb:GTF2H2(gene name)|psi-mi:GTF2H2(display_short)|uniprotkb:BTF2P44(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303794|imex:IM-27647-75 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_001506.1|refseq:XP_016864894.1|refseq:XP_016864895.1|refseq:XP_016864892.1|refseq:XP_016864893.1|dip:DIP-786N|ensembl:ENSG00000145736(gene)|ensembl:ENSG00000275045(gene)|ensembl:ENSG00000276910(gene)|ensembl:ENST00000274400(transcript)|ensembl:ENST00000330280(transcript)|ensembl:ENST00000612581(transcript)|ensembl:ENST00000617228(transcript)|ensembl:ENST00000619997(transcript)|ensembl:ENST00000628423(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004595(TFIIH C1-like, C-terminal)|interpro:IPR007198(Ssl1-like)|interpro:IPR012170(TFIIH basal transcription factor complex, subunit SSL1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036465|mint:Q13888|rcsb pdb:1Z60|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5O85|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:U4tPk4UlGiQz+exwhYG9kg7xGAM9606 rigid:koGrMfyrJ7DbrHfWOvpv0qJbyRc false binding-associated region:101-132|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q9Y5X3 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-715760|uniprotkb:Q52LC4|uniprotkb:B7ZKN3|uniprotkb:Q9BWP0|uniprotkb:Q7KZN0|uniprotkb:D3DW26|ensembl:ENSP00000366988|ensembl:ENSP00000366998 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:snx5_human(display_long)|uniprotkb:SNX5(gene name)|psi-mi:SNX5(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303794|imex:IM-27647-75 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_055241.1|refseq:NP_689413.1|ensembl:ENSG00000089006(gene)|ensembl:ENST00000377759(transcript)|ensembl:ENST00000377768(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006907"(pinocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070685"(macropinocytic cup)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097422"(tubular endosome)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028654|interpro:IPR036871|interpro:IPR042135|mint:Q9Y5X3|rcsb pdb:1SYS|rcsb pdb:5TGH|rcsb pdb:5TGI|rcsb pdb:5TGJ|rcsb pdb:5WY2|rcsb pdb:6N5X|rcsb pdb:6N5Y|rcsb pdb:6N5Z|reactome:R-HSA-432722 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:VR2oUxQ4M2bm5zKeHQlao046QL09606 rigid:koGrMfyrJ7DbrHfWOvpv0qJbyRc false binding-associated region:101-132|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q9UNH7 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-949294|ensembl:ENSP00000355217|uniprotkb:Q9Y449|uniprotkb:C0H5W9 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303794|imex:IM-27647-75 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 ensembl:ENSG00000129515(gene)|ensembl:ENST00000362031(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097422"(tubular endosome)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0016241"(regulation of macroautophagy)|interpro:IPR028657|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030904"(retromer complex)|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|go:"GO:0030905"(retromer, tubulation complex)|refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606 rigid:koGrMfyrJ7DbrHfWOvpv0qJbyRc false binding-associated region:101-132|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:O60749 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-1046690|uniprotkb:O43650|uniprotkb:P82862|uniprotkb:Q53XK8|uniprotkb:Q597H6|uniprotkb:Q9BTS8|ensembl:ENSP00000368831|uniprotkb:B3KN44|uniprotkb:B4DEK4|uniprotkb:B7Z408 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:snx2_human(display_long)|uniprotkb:Transformation-related gene 9 protein(gene name synonym)|uniprotkb:SNX2(gene name)|psi-mi:SNX2(display_short)|uniprotkb:TRG9(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303794|imex:IM-27647-75 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_003091.2|ensembl:ENSG00000205302(gene)|ensembl:ENST00000379516(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028653|interpro:IPR037918|mint:O60749|interpro:IPR036871|reactome:R-HSA-432722|refseq:NP_001265128.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:Sb/i4ZNGqy+ixeexnp0/4uOo3jo9606 rigid:koGrMfyrJ7DbrHfWOvpv0qJbyRc false binding-associated region:101-132|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q13596 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303794|imex:IM-27647-75 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528(gene)|ensembl:ENST00000559844(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|interpro:IPR036871|dip:DIP-398N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606 rigid:koGrMfyrJ7DbrHfWOvpv0qJbyRc false binding-associated region:101-132|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q14574 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-6163585|intact:EBI-28985956|uniprotkb:A6NN35|uniprotkb:Q14200|uniprotkb:Q9HAZ9|ensembl:ENSP00000353608 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:dsc3_human(display_long)|uniprotkb:Cadherin family member 3(gene name synonym)|uniprotkb:DSC4(gene name synonym)|uniprotkb:Desmocollin-4(gene name synonym)|uniprotkb:HT-CP(gene name synonym)|uniprotkb:DSC3(gene name)|psi-mi:DSC3(display_short)|uniprotkb:CDHF3(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_001932.2|refseq:NP_077741.2|ensembl:ENSP00000392068|ensembl:ENST00000434452|ensembl:ENSP00000353608|ensembl:ENSG00000134762(gene)|ensembl:ENST00000360428(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030057"(desmosome)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|mint:Q14574|reactome:R-HSA-6805567|reactome:R-HSA-6809371|interpro:IPR002126(Cadherin) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:2En63we0WgDfQQY2f4qQHK/clSI9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q92729 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-7052301|ensembl:ENSP00000334941|uniprotkb:Q59HA4|intact:MINT-1349420|uniprotkb:Q5SYU5|uniprotkb:O00197|uniprotkb:A6H8L1|uniprotkb:P78399|uniprotkb:Q92735|uniprotkb:Q5SYU4|uniprotkb:Q92850 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:ptpru_human(display_long)|uniprotkb:PTPRU(gene name)|psi-mi:PTPRU(display_short)|uniprotkb:PCP2(gene name synonym)|uniprotkb:FMI(gene name synonym)|uniprotkb:PTPRO(gene name synonym)|uniprotkb:Receptor-type protein-tyrosine phosphatase psi(gene name synonym)|uniprotkb:Pancreatic carcinoma phosphatase 2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor omicron(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase J(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase pi(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 ensembl:ENSG00000060656(gene)|ensembl:ENST00000345512(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000998(MAM)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|mint:Q92729|rcsb pdb:6SUB|rcsb pdb:6SUC|reactome:R-HSA-1433557|refseq:NP_001181930.1|refseq:NP_005695.3|refseq:NP_573439.2|refseq:NP_573438.3 - - comment:mint|function:Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Forms complexes with beta-catenin and gamma-catenin/plakoglobin figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:zEYsgwn37ANdzpiq5f8h2TL+XD89606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:P63000 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-413628|ensembl:ENSP00000258737|uniprotkb:O95501|uniprotkb:P15154|uniprotkb:Q3Y4D3|uniprotkb:Q5JAA8|uniprotkb:Q9BTB4 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:rac1_human(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:MIG5(orf name)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Ras-like protein TC25(gene name synonym)|uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)|uniprotkb:TC25(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 ensembl:ENSG00000136238(gene)|ensembl:ENST00000348035(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002551"(mast cell chemotaxis)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006954"(inflammatory response)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031529"(ruffle organization)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032707"(negative regulation of interleukin-23 production)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042470"(melanosome)|reactome:R-HSA-2424491|refseq:NP_008839.2|refseq:NP_061485.1|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051668"(localization within membrane)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902622"(regulation of neutrophil migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P63000|rcsb pdb:1E96|rcsb pdb:1FOE|rcsb pdb:1G4U|rcsb pdb:1HE1|rcsb pdb:1HH4|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:1I4T|rcsb pdb:1MH1|rcsb pdb:1RYF|rcsb pdb:1RYH|rcsb pdb:2FJU|rcsb pdb:2H7V|rcsb pdb:2NZ8|rcsb pdb:2P2L|rcsb pdb:2RMK|rcsb pdb:2VRW|rcsb pdb:2WKP|rcsb pdb:2WKQ|rcsb pdb:2WKR|rcsb pdb:2YIN|rcsb pdb:3B13|rcsb pdb:3BJI|rcsb pdb:3RYT|rcsb pdb:3SBD|rcsb pdb:3SBE|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:3TH5|rcsb pdb:4GZL|rcsb pdb:4GZM|rcsb pdb:4YON|rcsb pdb:5FI0|rcsb pdb:5HZH|rcsb pdb:5N6O|rcsb pdb:5O33|rcsb pdb:5QQD|rcsb pdb:5QQE|rcsb pdb:5QQF|rcsb pdb:5QQG|rcsb pdb:5QQH|rcsb pdb:5QQI|rcsb pdb:5QQJ|rcsb pdb:5QQK|rcsb pdb:5QQL|rcsb pdb:5QQM|rcsb pdb:5QQN|rcsb pdb:5QU9|rcsb pdb:6AGP|rcsb pdb:6BC1|rcsb pdb:6TGC|rcsb pdb:6X1G|rcsb pdb:7AJK|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1445148|reactome:R-HSA-164944|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0045453"(bone resorption)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051492"(regulation of stress fiber assembly)|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-389359|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-4086400|reactome:R-HSA-416550|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5668599|reactome:R-HSA-5687128|reactome:R-HSA-6798695|reactome:R-HSA-6811558|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-9013149|reactome:R-HSA-9032759|reactome:R-HSA-9032845|reactome:R-HSA-9619229|reactome:R-HSA-9664422|reactome:R-HSA-9673324|reactome:R-HSA-983231|reactome:R-HSA-2871796|reactome:R-HSA-376172|dip:DIP-29260N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q9BWL3 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-16771163|ensembl:ENSP00000357507|uniprotkb:A8K3G8|uniprotkb:D3DV72|uniprotkb:D3DV74|uniprotkb:Q5M801|uniprotkb:Q5VU73|uniprotkb:Q5VU83|uniprotkb:Q96HP7|uniprotkb:Q9UFU2|uniprotkb:Q9UGL7|uniprotkb:Q9UGL8|uniprotkb:Q9Y2R6 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:ca043_human(display_long)|uniprotkb:C1orf43(gene name)|psi-mi:C1orf43(display_short)|uniprotkb:NICE3(gene name synonym)|uniprotkb:NS5ATP4(gene name synonym)|uniprotkb:Hepatitis C virus NS5A-transactivated protein 4(gene name synonym)|uniprotkb:Protein NICE-3(gene name synonym)|uniprotkb:S863-3(gene name synonym)|uniprotkb:HSPC012(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 ensembl:ENST00000350592|ensembl:ENSP00000271925|ensembl:ENST00000362076|ensembl:ENSP00000354496|ensembl:ENST00000368518|ensembl:ENSP00000357504|ensembl:ENSP00000357507|ensembl:ENSG00000143612(gene)|ensembl:ENST00000368521(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006909"(phagocytosis)|go:"GO:0016021"(integral component of membrane)|interpro:IPR010876(NICE-3)|mint:Q9BWL3|refseq:NP_001092086.1|refseq:NP_001284646.1|refseq:NP_001284647.1|refseq:NP_001284649.1|refseq:NP_001284650.1|refseq:NP_001284652.1|refseq:NP_056264.1|refseq:NP_620077.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:L5dPZ3YNGbmbzVR0nb+Gjzz5H5s9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q13190 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-714206|uniprotkb:Q5U0D4|uniprotkb:Q7Z3T6|uniprotkb:Q9BUG1|uniprotkb:B2R8T2|ensembl:ENSP00000294179|uniprotkb:F8W8Q9 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:stx5_human(display_long)|uniprotkb:STX5(gene name)|psi-mi:STX5(display_short)|uniprotkb:STX5A(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_003155.2|ensembl:ENSG00000162236(gene)|ensembl:ENST00000294179(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048278"(vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0090166"(Golgi disassembly)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|mint:Q13190|rcsb pdb:3EFO|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-8980692|reactome:R-HSA-9013106|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-9013408|reactome:R-HSA-9609523|refseq:NP_001231595.1|refseq:NP_001317223.1|dip:DIP-56987N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:cR4cS695ZWQQ5Bkim9HqmCE0hCE9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q5SWA1 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-2815482|uniprotkb:Q53GQ4|uniprotkb:Q96SN1|uniprotkb:Q6P156|uniprotkb:Q658M2|ensembl:ENSP00000356156 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:pr15b_human(display_long)|uniprotkb:PPP1R15B(gene name)|psi-mi:PPP1R15B(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 ensembl:ENSG00000158615(gene)|ensembl:ENST00000367188(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006983"(ER overload response)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|interpro:IPR019512|interpro:IPR019523|mint:Q5SWA1|rcsb pdb:4V0U|rcsb pdb:4V0V|rcsb pdb:4V0W|rcsb pdb:4V0X|go:"GO:0034976"(response to endoplasmic reticulum stress) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:EBWZBipo2XhGvdskPjJVlLSo5T89606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q9BQT9 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-11291074|uniprotkb:D3DUT6|uniprotkb:O94831|uniprotkb:Q2T9J5|uniprotkb:Q5UE57|ensembl:ENSP00000266546|ensembl:ENSP00000500510 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:cstn3_human(display_long)|uniprotkb:CLSTN3(gene name)|psi-mi:CLSTN3(display_short)|uniprotkb:CS3(gene name synonym)|uniprotkb:KIAA0726(gene name synonym)|uniprotkb:Alcadein-beta(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_055533.2|refseq:XP_006719226.1|ensembl:ENSG00000139182(gene)|ensembl:ENSG00000288427(gene)|ensembl:ENST00000266546(transcript)|ensembl:ENST00000672495(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0009986"(cell surface)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1902474"(positive regulation of protein localization to synapse)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR026914|mint:Q9BQT9 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:6rGsIDkSoXvlLtfjgJ/dp0TEPU89606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q96AG4 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|ensembl:ENSP00000225972|uniprotkb:B2RE83 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_060979.2|ensembl:ENSG00000108829(gene)|ensembl:ENST00000225972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045296"(cadherin binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q96AG4 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q9BRR6 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-723761|uniprotkb:Q49AU7|uniprotkb:Q8NBI1|uniprotkb:Q8WZ90|uniprotkb:Q96NF8|uniprotkb:Q9H0A7|ensembl:ENSP00000397694 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:adpgk_human(display_long)|uniprotkb:RbBP-35(gene name synonym)|uniprotkb:ADPGK(gene name)|psi-mi:ADPGK(display_short)|uniprotkb:PSEC0260(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_112574.3|refseq:XP_006720775.1|ensembl:ENSG00000159322(gene)|ensembl:ENST00000456471(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0043843"(ADP-specific glucokinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0061620"(glycolytic process through glucose-6-phosphate)|interpro:IPR007666(ADP-specific phosphofructokinase/glucokinase)|mint:Q9BRR6|reactome:R-HSA-70171|interpro:IPR029056 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:jeRKymflPO3JABiI6J42cZZEbwc9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:O94874 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-1048088|intact:EBI-2798769|uniprotkb:Q8N765|uniprotkb:Q9NTQ0|uniprotkb:A0PJ53|uniprotkb:B4DJ57|uniprotkb:C0H5X5|ensembl:ENSP00000358283 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:ufl1_human(display_long)|uniprotkb:UFL1(gene name)|psi-mi:UFL1(display_short)|uniprotkb:E3 UFM1-protein transferase 1(gene name synonym)|uniprotkb:KIAA0776(gene name synonym)|uniprotkb:Novel LZAP-binding protein(gene name synonym)|uniprotkb:RCAD(gene name synonym)|uniprotkb:Regulator of C53/LZAP and DDRGK1(gene name synonym)|uniprotkb:NLBP(gene name synonym)|uniprotkb:MAXER(gene name synonym)|uniprotkb:Multiple alpha-helix protein located at ER(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_056138.1|ensembl:ENSG00000014123(gene)|ensembl:ENST00000369278(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0016570"(histone modification)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0061666"(UFM1 ligase activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0071568"(UFM1 transferase activity)|go:"GO:0071569"(protein ufmylation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1990592"(protein K69-linked ufmylation)|interpro:IPR018611|mint:O94874|reactome:R-HSA-983168 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:wiJotyDNle7GoYzFkOif0TFNr2w9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q9Y2U8 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-2561428|ensembl:ENSP00000308369|uniprotkb:Q9NT47|uniprotkb:Q9NYA5 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:man1_human(display_long)|uniprotkb:MAN1(gene name synonym)|uniprotkb:LEM domain-containing protein 3(gene name synonym)|uniprotkb:LEMD3(gene name)|psi-mi:LEMD3(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 ensembl:ENSG00000174106(gene)|ensembl:ENST00000308330(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:1902531"(regulation of intracellular signal transduction)|go:"GO:0031965"(nuclear membrane)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018996|interpro:IPR034394|interpro:IPR034997|interpro:IPR035979|interpro:IPR041885|mint:Q9Y2U8|rcsb pdb:2CH0|rcsb pdb:5ZOJ|rcsb pdb:5ZOK|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_001161086.1|refseq:NP_055134.2 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:8AILzxAZLbxCAzlJ7oPg9WybOmY9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q9NNW5 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-1568315|uniprotkb:B4DHK2|uniprotkb:Q3MIT1|uniprotkb:Q9UF63|ensembl:ENSP00000477389 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:wdr6_human(display_long)|uniprotkb:WDR6(gene name)|psi-mi:WDR6(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_060501.3|refseq:NP_001307475.1|refseq:NP_001307476.1|ensembl:ENSG00000178252(gene)|ensembl:ENST00000608424(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0030488"(tRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9NNW5|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:gYSDkyuDdKhj387/1P3bhpKJXy89606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:O15400 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-3221827|ensembl:ENSP00000356918|uniprotkb:Q5SZW2|uniprotkb:Q96ES9|uniprotkb:E1P579 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:stx7_human(display_long)|uniprotkb:STX7(gene name)|psi-mi:STX7(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 ensembl:ENSG00000079950(gene)|ensembl:ENST00000367941(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001772"(immunological synapse)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042582"(azurophil granule)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051640"(organelle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070820"(tertiary granule)|go:"GO:0070925"(organelle assembly)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|mint:O15400|refseq:XP_011534480.1|refseq:NP_003560.2|refseq:NP_001313507.1|refseq:NP_001313508.1|refseq:NP_001313509.1|dip:DIP-57384N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:lFaq26g0qeP7ObMMKexuZamQgps9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q8IY95 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-4324723|uniprotkb:Q7Z3A1|uniprotkb:Q8N928|ensembl:ENSP00000305069 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:tm192_human(display_long)|uniprotkb:TMEM192(gene name)|psi-mi:TMEM192(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_001093859.1|ensembl:ENSG00000170088(gene)|ensembl:ENST00000306480(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR029399|mint:Q8IY95 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:b2RQelAEDWcwiZ0w8/tgiEmeBX09606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q9NUM4 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-10490807|uniprotkb:Q53FL9|uniprotkb:A4D108|uniprotkb:Q8N4L0|ensembl:ENSP00000379901|ensembl:ENSP00000379902 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:t106b_human(display_long)|uniprotkb:TMEM106B(gene name)|psi-mi:TMEM106B(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_001127704.1|refseq:NP_060844.2|refseq:XP_005249846.1|ensembl:ENSG00000106460(gene)|ensembl:ENST00000396667(transcript)|ensembl:ENST00000396668(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051117"(ATPase binding)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1905146"(lysosomal protein catabolic process)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR009790(Protein of unknown function DUF1356)|mint:Q9NUM4 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:RdOP7hFA+H8Tjb/iLZrdShpfJmg9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q86Y82 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-2691717|uniprotkb:B1AJQ7|uniprotkb:O95564|ensembl:ENSP00000363054 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:stx12_human(display_long)|uniprotkb:STX12(gene name)|psi-mi:STX12(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_803173.1|ensembl:ENSG00000117758(gene)|ensembl:ENST00000373943(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048278"(vesicle docking)|go:"GO:0050821"(protein stabilization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0098837"(postsynaptic recycling endosome)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|mint:Q86Y82|rcsb pdb:2DNX|dip:DIP-44225N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:kSTOaE08HK8SpI19dBZRZbOVCGw9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q9Y6I9 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-10329860|uniprotkb:Q9UKD7|uniprotkb:B3KN87|ensembl:ENSP00000340969|ensembl:ENSP00000378497|ensembl:ENSP00000396628|ensembl:ENSP00000398802|ensembl:ENSP00000408186|ensembl:ENSP00000477946 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:tx264_human(display_long)|uniprotkb:TEX264(gene name)|psi-mi:TEX264(display_short)|uniprotkb:Putative secreted protein Zsig11(gene name synonym)|uniprotkb:ZSIG11(gene name synonym)|uniprotkb:UNQ337/PRO536(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_001123356.1|refseq:NP_001230654.1|refseq:NP_001230655.1|refseq:NP_001230656.1|refseq:NP_001265124.1|refseq:NP_057010.1|refseq:XP_006713258.1|refseq:XP_006713260.1|refseq:XP_011532107.1|ensembl:ENSG00000164081(gene)|ensembl:ENST00000341333(transcript)|ensembl:ENST00000395057(transcript)|ensembl:ENST00000415259(transcript)|ensembl:ENST00000416589(transcript)|ensembl:ENST00000457573(transcript)|ensembl:ENST00000611400(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|interpro:IPR011256(Regulatory factor, effector, bacterial)|mint:Q9Y6I9|reactome:R-HSA-114608|go:"GO:0005829"(cytosol) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:Agv5w3SF9VdUL0o2qXZ7erRtyJ09606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q9UET6 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-1055987|uniprotkb:O75670|uniprotkb:B2RCJ0|ensembl:ENSP00000326948 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:trm7_human(display_long)|uniprotkb:FTSJ1(gene name)|psi-mi:FTSJ1(display_short)|uniprotkb:JM23(orf name)|uniprotkb:Protein ftsJ homolog 1(gene name synonym)|uniprotkb:2'-O-ribose RNA methyltransferase TRM7 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_036412.1|refseq:NP_803188.1|refseq:NP_001269086.1|refseq:XP_005272652.1|ensembl:ENST00000348411(transcript)|go:"GO:0001510"(RNA methylation)|go:"GO:0002128"(tRNA nucleoside ribose methylation)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008175"(tRNA methyltransferase activity)|go:"GO:0009020"("tRNA (guanosine-2'-O-)-methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|go:"GO:0052666"("tRNA (cytosine-2'-O-)-methyltransferase activity")|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR015507(Ribosomal RNA methyltransferase J)|interpro:IPR028590|interpro:IPR029063|mint:Q9UET6|reactome:R-HSA-6782315|ensembl:ENSG00000068438(gene) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:N4L9nsU0Wj3FMVjYALdxpx56aZs9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q9P2W9 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-725334|uniprotkb:Q596L3|uniprotkb:Q5TZP5|ensembl:ENSP00000305810 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:stx18_human(display_long)|uniprotkb:Cell growth-inhibiting gene 9 protein(gene name synonym)|uniprotkb:STX18(gene name)|psi-mi:STX18(display_short)|uniprotkb:GIG9(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_058626.1|refseq:NP_001333211.1|refseq:NP_001333210.1|refseq:NP_001333229.1|ensembl:ENSG00000168818(gene)|ensembl:ENST00000306200(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|go:"GO:1902117"(positive regulation of organelle assembly)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR019529|mint:Q9P2W9|reactome:R-HSA-6811434|dip:DIP-37617N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:QpvkckDM1D5Jaty6AmK3vEwRZts9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:P98172 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-538287|uniprotkb:D3DVU0|ensembl:ENSP00000204961 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:efnb1_human(display_long)|uniprotkb:EPH-related receptor tyrosine kinase ligand 2(gene name synonym)|uniprotkb:EFL3(gene name synonym)|uniprotkb:EFNB1(gene name)|psi-mi:EFNB1(display_short)|uniprotkb:EFL-3(gene name synonym)|uniprotkb:EPLG2(gene name synonym)|uniprotkb:LERK2(gene name synonym)|uniprotkb:ELK ligand(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_004420.1|ensembl:ENSG00000090776(gene)|ensembl:ENST00000204961(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007411"(axon guidance)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031295"(T cell costimulation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034255|mint:P98172|rcsb pdb:6THG|reactome:R-HSA-2682334|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:s9RYPWXKQ2QMzvfGluiliH3YC3s9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q12907 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-3915406|uniprotkb:Q53HH1|ensembl:ENSP00000303366 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:lman2_human(display_long)|uniprotkb:LMAN2(gene name)|psi-mi:LMAN2(display_short)|uniprotkb:C5orf8(gene name synonym)|uniprotkb:Glycoprotein GP36b(gene name synonym)|uniprotkb:Lectin mannose-binding 2(gene name synonym)|uniprotkb:Vesicular integral-membrane protein 36(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_006807.1|ensembl:ENSG00000169223(gene)|ensembl:ENST00000303127(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR035664|mint:Q12907|reactome:R-HSA-204005|reactome:R-HSA-5694530 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:goqUZGW9/lvVMWDAZS9csH3TqWY9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:P30447 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-1046240|uniprotkb:Q9TQF1|uniprotkb:Q9TQF8|uniprotkb:Q9TQG5|uniprotkb:Q9TQM6 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:1a23_human(display_long)|uniprotkb:MHC class I antigen A*23(gene name synonym)|uniprotkb:HLA class I histocompatibility antigen, A-9 alpha chain(gene name synonym)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 ensembl:ENST00000454091|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0009986"(cell surface)|go:"GO:0030881"(beta-2-microglobulin binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042612"(MHC class I protein complex)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|ensembl:ENSG00000223980|ensembl:ENSP00000410645|go:"GO:0000139"(Golgi membrane)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0005886"(plasma membrane)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0050776"(regulation of immune response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR036179|interpro:IPR037055 - - no-uniprot-update:This interactor won't be updated using Uniprot. figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:RuTq2GS3tPQEFt5Pbhm5IOpWa0Y9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q9Y5X3 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-715760|uniprotkb:Q52LC4|uniprotkb:B7ZKN3|uniprotkb:Q9BWP0|uniprotkb:Q7KZN0|uniprotkb:D3DW26|ensembl:ENSP00000366988|ensembl:ENSP00000366998 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:snx5_human(display_long)|uniprotkb:SNX5(gene name)|psi-mi:SNX5(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_055241.1|refseq:NP_689413.1|ensembl:ENSG00000089006(gene)|ensembl:ENST00000377759(transcript)|ensembl:ENST00000377768(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006907"(pinocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070685"(macropinocytic cup)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097422"(tubular endosome)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028654|interpro:IPR036871|interpro:IPR042135|mint:Q9Y5X3|rcsb pdb:1SYS|rcsb pdb:5TGH|rcsb pdb:5TGI|rcsb pdb:5TGJ|rcsb pdb:5WY2|rcsb pdb:6N5X|rcsb pdb:6N5Y|rcsb pdb:6N5Z|reactome:R-HSA-432722 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:VR2oUxQ4M2bm5zKeHQlao046QL09606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q9UNH7 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-949294|ensembl:ENSP00000355217|uniprotkb:Q9Y449|uniprotkb:C0H5W9 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 ensembl:ENSG00000129515(gene)|ensembl:ENST00000362031(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097422"(tubular endosome)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0016241"(regulation of macroautophagy)|interpro:IPR028657|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030904"(retromer complex)|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|go:"GO:0030905"(retromer, tubulation complex)|refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q9BY67 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-5652260|uniprotkb:Q86WB8|uniprotkb:Q8N2F4|uniprotkb:A4FVB5|uniprotkb:F5H0J4|uniprotkb:H0YGA7|uniprotkb:H1ZZV9|uniprotkb:H1ZZW1|uniprotkb:H1ZZW2|uniprotkb:X5D2C8|ensembl:ENSP00000395359 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:cadm1_human(display_long)|uniprotkb:CADM1(gene name)|psi-mi:CADM1(display_short)|uniprotkb:IGSF4(gene name synonym)|uniprotkb:IGSF4A(gene name synonym)|uniprotkb:NECL2(gene name synonym)|uniprotkb:SYNCAM(gene name synonym)|uniprotkb:TSLC1(gene name synonym)|uniprotkb:Immunoglobulin superfamily member 4(gene name synonym)|uniprotkb:Nectin-like protein 2(gene name synonym)|uniprotkb:Spermatogenic immunoglobulin superfamily(gene name synonym)|uniprotkb:Synaptic cell adhesion molecule(gene name synonym)|uniprotkb:Tumor suppressor in lung cancer 1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_001287972.1|refseq:NP_001287973.1|refseq:NP_001287974.1|refseq:NP_001091987.1|refseq:NP_055148.3|dip:DIP-57599N|go:"GO:0042271"(susceptibility to natural killer cell mediated cytotoxicity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045202"(synapse)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0051606"(detection of stimulus)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:Q9BY67|rcsb pdb:3BIN|rcsb pdb:4H5S|reactome:R-HSA-418990|reactome:R-HSA-420597|go:"GO:0030165"(PDZ domain binding)|ensembl:ENSG00000182985(gene)|ensembl:ENST00000452722(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002376"(immune system process)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008037"(cell recognition)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030154"(cell differentiation) - - crc64:CDEDE1E0C08BDD3A figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:870cLsl7OEZV3iLs+IaE2V/UW4o9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:O60749 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-1046690|uniprotkb:O43650|uniprotkb:P82862|uniprotkb:Q53XK8|uniprotkb:Q597H6|uniprotkb:Q9BTS8|ensembl:ENSP00000368831|uniprotkb:B3KN44|uniprotkb:B4DEK4|uniprotkb:B7Z408 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:snx2_human(display_long)|uniprotkb:Transformation-related gene 9 protein(gene name synonym)|uniprotkb:SNX2(gene name)|psi-mi:SNX2(display_short)|uniprotkb:TRG9(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_003091.2|ensembl:ENSG00000205302(gene)|ensembl:ENST00000379516(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028653|interpro:IPR037918|mint:O60749|interpro:IPR036871|reactome:R-HSA-432722|refseq:NP_001265128.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:Sb/i4ZNGqy+ixeexnp0/4uOo3jo9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q13596 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528(gene)|ensembl:ENST00000559844(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|interpro:IPR036871|dip:DIP-398N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q04206 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-73886|ensembl:ENSP00000384273|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 ensembl:ENSG00000173039(gene)|ensembl:ENST00000406246(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|refseq:NP_001138610.1|refseq:NP_068810.3|refseq:NP_001230913.1|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0070301"(cellular response to hydrogen peroxide)|dip:DIP-24238N|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0051607"(defense response to virus)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIY|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q5VV42 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-10194801|uniprotkb:Q6P385|uniprotkb:Q6ZR27|uniprotkb:A8K6S0|uniprotkb:Q9NXB3|ensembl:ENSP00000274695|ensembl:ENSP00000367873 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:cdkal_human(display_long)|uniprotkb:CDKAL1(gene name)|psi-mi:CDKAL1(display_short)|uniprotkb:CDK5 regulatory subunit-associated protein 1-like 1(gene name synonym)|uniprotkb:"tRNA-t(6)A37 methylthiotransferase"(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_060244.2|ensembl:ENSG00000145996(gene)|ensembl:ENST00000274695(transcript)|ensembl:ENST00000378610(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035598"(N6-threonylcarbomyladenosine methylthiotransferase activity)|go:"GO:0035600"(tRNA methylthiolation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061712"("tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase")|go:"GO:1990145"(maintenance of translational fidelity)|interpro:IPR002792(Deoxyribonuclease/rho motif-related TRAM)|interpro:IPR005839(Protein of unknown function UPF0004)|interpro:IPR006466(MiaB-like tRNA modifying enzyme, archaeal-type)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR013848(Protein of unknown function UPF0004, N-terminal)|interpro:IPR020612|interpro:IPR023404|interpro:IPR038135|mint:Q5VV42|reactome:R-HSA-6782315 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:wBMBRPqWqalOHuLyrwr+2KvlHoQ9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q68DH5 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-20858131|ensembl:ENSP00000296603|uniprotkb:B3KRB6|uniprotkb:Q9NTC7 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:lmbd2_human(display_long)|uniprotkb:LMBRD2(gene name)|psi-mi:LMBRD2(display_short)|uniprotkb:LMBR1 domain-containing protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 ensembl:ENSG00000164187(gene)|ensembl:ENST00000296603(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071875"(adrenergic receptor signaling pathway)|interpro:IPR006876(LMBR1-like conserved region)|mint:Q68DH5|refseq:NP_001007528.1|refseq:XP_011512464.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:q2WB24Dd8SLHl38AcRDvDE/k8zs9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:P19022 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-2256711|uniprotkb:Q14923|uniprotkb:Q8N173|uniprotkb:A8MWK3|uniprotkb:B0YIY6|ensembl:ENSP00000269141|intact:EBI-28986933 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:cadh2_human(display_long)|uniprotkb:CDH2(gene name)|psi-mi:CDH2(display_short)|uniprotkb:CDHN(gene name synonym)|uniprotkb:NCAD(gene name synonym)|uniprotkb:Neural cadherin(gene name synonym)|uniprotkb:CDw325(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_001295105.1|refseq:NP_001783.2|go:"GO:0045177"(apical part of cell)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090497"(mesenchymal cell migration)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030051|interpro:IPR039808|mint:P19022|reactome:R-HSA-381426|reactome:R-HSA-418990|reactome:R-HSA-525793|reactome:R-HSA-8957275|go:"GO:0044853"(plasma membrane raft)|dip:DIP-43894N|ensembl:ENSG00000170558(gene)|ensembl:ENST00000269141(transcript)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|ensembl:ENSP00000269141|ensembl:ENST00000399380|ensembl:ENSP00000382312 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:lo+u8oH3T9OYU56F5MgXKmwEhuI9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q9Y2J2 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-310986|uniprotkb:O95713|uniprotkb:Q9BRP5|ensembl:ENSP00000343158|uniprotkb:B7Z4I5|uniprotkb:F5GX05 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:e41l3_human(display_long)|uniprotkb:EPB41L3(gene name)|psi-mi:EPB41L3(display_short)|uniprotkb:DAL1(gene name synonym)|uniprotkb:KIAA0987(gene name synonym)|uniprotkb:4.1B(gene name synonym)|uniprotkb:Differentially expressed in adenocarcinoma of the lung protein 1(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 3(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_036439.2|refseq:NP_001268462.1|refseq:NP_001268463.1|refseq:NP_001268464.1|ensembl:ENSG00000082397(gene)|ensembl:ENST00000341928(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0002175"(protein localization to paranode region of axon)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030054"(cell junction)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0033270"(paranode region of axon)|go:"GO:0043217"(myelin maintenance)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0071205"(protein localization to juxtaparanode region of axon)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030691|interpro:IPR035963|mint:Q9Y2J2|rcsb pdb:2HE7|rcsb pdb:3BIN|rcsb pdb:5RYM|rcsb pdb:5RYN|rcsb pdb:5RYO|rcsb pdb:5RYP|rcsb pdb:5RYQ|rcsb pdb:5RYR|rcsb pdb:5RYS|rcsb pdb:5RYT|rcsb pdb:5RYU|rcsb pdb:5RYV|rcsb pdb:5RYW|rcsb pdb:5RYX|rcsb pdb:5RYY|rcsb pdb:5RYZ|rcsb pdb:5RZ0|rcsb pdb:5RZ1|rcsb pdb:5RZ2|rcsb pdb:5RZ3|rcsb pdb:5RZ4|rcsb pdb:5RZ5|rcsb pdb:5RZ6|rcsb pdb:5RZ7|rcsb pdb:5RZ8|rcsb pdb:5RZ9|rcsb pdb:5RZA|rcsb pdb:5RZB|rcsb pdb:5RZC|rcsb pdb:5RZD|rcsb pdb:5RZE|rcsb pdb:5RZF|rcsb pdb:5RZG|rcsb pdb:5RZH|rcsb pdb:5RZI|rcsb pdb:5RZJ|rcsb pdb:5RZK|rcsb pdb:5RZL|rcsb pdb:5RZM|rcsb pdb:5RZN|rcsb pdb:5RZO|rcsb pdb:5RZP|rcsb pdb:5RZQ|rcsb pdb:5RZR|rcsb pdb:5RZS|rcsb pdb:5RZT|rcsb pdb:5RZU|rcsb pdb:5RZV|rcsb pdb:5RZW|rcsb pdb:5RZX|rcsb pdb:5RZY|rcsb pdb:5RZZ|rcsb pdb:5S00|rcsb pdb:6IBE|reactome:R-HSA-6794361|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:XP_016881125.1|dip:DIP-17035N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:Uwq5dqLRdgFLPBhXZROSRJstl709606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:P00533 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-297353|uniprotkb:Q9BZS2|uniprotkb:Q9GZX1|uniprotkb:Q9H2C9|uniprotkb:Q9H3C9|uniprotkb:Q9UMD7|uniprotkb:Q9UMD8|uniprotkb:Q9UMG5|uniprotkb:O00688|uniprotkb:O00732|uniprotkb:P06268|uniprotkb:Q14225|uniprotkb:Q92795|intact:EBI-28985169|ensembl:ENSP00000275493|uniprotkb:Q68GS5 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:egfr_human(display_long)|uniprotkb:ERBB1(gene name synonym)|uniprotkb:EGFR(gene name)|psi-mi:EGFR(display_short)|uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym)|uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym)|uniprotkb:ERBB(gene name synonym)|uniprotkb:HER1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 ensembl:ENSG00000146648(gene)|ensembl:ENST00000275493(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001503"(ossification)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005006"(epidermal growth factor-activated receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0007494"(midgut development)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035690"|go:"GO:0007611"(learning or memory)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042311"(vasodilation)|go:"GO:0033594"(response to hydroxyisoflavone)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042698"(ovulation cycle)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043006"(activation of phospholipase A2 activity by calcium-mediated signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043586"(tongue development)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010750"(positive regulation of nitric oxide mediated signal transduction)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016101"(diterpenoid metabolic process)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032930"(positive regulation of superoxide anion generation)|rcsb pdb:4WD5|rcsb pdb:4WKQ|rcsb pdb:4WRG|rcsb pdb:4ZAU|rcsb pdb:4ZJV|rcsb pdb:4ZSE|rcsb pdb:5C8K|rcsb pdb:5C8M|rcsb pdb:5C8N|rcsb pdb:5CAL|rcsb pdb:5CAN|rcsb pdb:5CAO|rcsb pdb:5CAP|rcsb pdb:5CAQ|rcsb pdb:4UV7|rcsb pdb:5CAS|rcsb pdb:5CAU|rcsb pdb:5CAV|rcsb pdb:5CNN|rcsb pdb:5CNO|rcsb pdb:5CZH|rcsb pdb:5CZI|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048143"(astrocyte activation)|go:"GO:0048408"(epidermal growth factor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051205"(protein insertion into membrane)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|rcsb pdb:5UGB|rcsb pdb:5UGC|rcsb pdb:5UWD|rcsb pdb:5WB7|rcsb pdb:5WB8|rcsb pdb:5X26|rcsb pdb:5X27|rcsb pdb:5X28|rcsb pdb:5X2A|rcsb pdb:5X2C|rcsb pdb:5X2F|rcsb pdb:5X2K|rcsb pdb:5XDK|rcsb pdb:5XDL|rcsb pdb:5XGM|rcsb pdb:5XGN|rcsb pdb:5XWD|rcsb pdb:5Y25|rcsb pdb:5Y9T|rcsb pdb:5YU9|rcsb pdb:5ZTO|rcsb pdb:5ZWJ|rcsb pdb:6ARU|rcsb pdb:6B3S|rcsb pdb:5D41|rcsb pdb:6D8E|rcsb pdb:6DUK|rcsb pdb:6JRJ|rcsb pdb:6JRK|rcsb pdb:6JRX|rcsb pdb:6JWL|rcsb pdb:6JX0|rcsb pdb:6JX4|rcsb pdb:6JXT|rcsb pdb:6JZ0|go:"GO:0097489"(multivesicular body, internal vesicle lumen)|go:"GO:0097708"(intracellular vesicle)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900020"(positive regulation of protein kinase C activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902722"(positive regulation of prolactin secretion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905208"(negative regulation of cardiocyte differentiation)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070141"(response to UV-A)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070435"(Shc-EGFR complex)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|mint:P00533|rcsb pdb:1DNQ|rcsb pdb:1DNR|rcsb pdb:1IVO|rcsb pdb:1M14|rcsb pdb:1M17|rcsb pdb:1MOX|rcsb pdb:1NQL|rcsb pdb:1XKK|rcsb pdb:1YY9|rcsb pdb:1Z9I|rcsb pdb:2EB2|rcsb pdb:2EB3|rcsb pdb:2EXP|rcsb pdb:2EXQ|rcsb pdb:2GS2|rcsb pdb:2GS6|rcsb pdb:2J5E|rcsb pdb:2J5F|rcsb pdb:2GS7|rcsb pdb:2J6M|rcsb pdb:2JIT|rcsb pdb:2ITN|rcsb pdb:2JIU|rcsb pdb:2ITO|rcsb pdb:2JIV|rcsb pdb:2KS1|rcsb pdb:2ITP|rcsb pdb:2M0B|rcsb pdb:2M20|rcsb pdb:2ITQ|rcsb pdb:2N5S|rcsb pdb:2RF9|rcsb pdb:2RFD|rcsb pdb:2RFE|rcsb pdb:2RGP|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BEL|rcsb pdb:2ITT|rcsb pdb:3BUO|rcsb pdb:3C09|rcsb pdb:3G5V|rcsb pdb:3G5Y|rcsb pdb:3GOP|rcsb pdb:3GT8|rcsb pdb:3IKA|rcsb pdb:3LZB|rcsb pdb:2ITU|rcsb pdb:3NJP|rcsb pdb:3OB2|rcsb pdb:2ITV|rcsb pdb:3OP0|rcsb pdb:2ITW|rcsb pdb:2ITX|rcsb pdb:2ITY|rcsb pdb:3P0Y|rcsb pdb:2ITZ|rcsb pdb:3PFV|rcsb pdb:3POZ|rcsb pdb:3QWQ|rcsb pdb:3UG1|rcsb pdb:3UG2|rcsb pdb:3VJN|rcsb pdb:3VJO|rcsb pdb:3VRP|rcsb pdb:3VRR|rcsb pdb:5EM7|rcsb pdb:5EM8|rcsb pdb:5FED|rcsb pdb:5FEE|rcsb pdb:5FEQ|rcsb pdb:5GMP|rcsb pdb:5GNK|rcsb pdb:5GTY|rcsb pdb:5GTZ|rcsb pdb:5HCX|rcsb pdb:5HCY|rcsb pdb:5HCZ|rcsb pdb:5HG5|rcsb pdb:5HG7|rcsb pdb:5HG8|rcsb pdb:5HG9|rcsb pdb:5HIB|rcsb pdb:5HIC|rcsb pdb:5EDP|rcsb pdb:5J9Y|rcsb pdb:5J9Z|rcsb pdb:5JEB|rcsb pdb:5LV6|rcsb pdb:5SX4|rcsb pdb:5EDQ|rcsb pdb:5EDR|rcsb pdb:5EM5|rcsb pdb:5SX5|rcsb pdb:5U8L|rcsb pdb:5UG8|rcsb pdb:5EM6|rcsb pdb:5UG9|rcsb pdb:5UGA|rcsb pdb:3W2O|rcsb pdb:4JR3|rcsb pdb:3W2P|rcsb pdb:3W2Q|rcsb pdb:4JRV|rcsb pdb:4KRL|rcsb pdb:4KRM|rcsb pdb:4KRO|rcsb pdb:3W2R|rcsb pdb:4KRP|rcsb pdb:4LI5|rcsb pdb:4LL0|rcsb pdb:3W2S|rcsb pdb:4LQM|rcsb pdb:4LRM|rcsb pdb:3W32|rcsb pdb:4R3P|rcsb pdb:4R3R|rcsb pdb:4R5S|rcsb pdb:3W33|rcsb pdb:4RIW|rcsb pdb:4G5J|rcsb pdb:4RIX|rcsb pdb:4G5P|rcsb pdb:4RIY|rcsb pdb:4RJ4|rcsb pdb:4RJ5|rcsb pdb:4HJO|rcsb pdb:4I1Z|rcsb pdb:4I20|rcsb pdb:4I21|rcsb pdb:4I22|rcsb pdb:4I23|rcsb pdb:4I24|rcsb pdb:4JQ7|rcsb pdb:4JQ8|rcsb pdb:4RJ6|rcsb pdb:4RJ7|rcsb pdb:4RJ8|rcsb pdb:4TKS|rcsb pdb:4UIP|rcsb pdb:6LUD|rcsb pdb:6P1D|rcsb pdb:6P1L|rcsb pdb:6P8Q|rcsb pdb:6S89|rcsb pdb:6S8A|rcsb pdb:6S9B|rcsb pdb:6S9C|rcsb pdb:6S9D|rcsb pdb:6TFU|rcsb pdb:6LUB|rcsb pdb:6TFV|rcsb pdb:6TFW|rcsb pdb:6TFY|rcsb pdb:6TFZ|rcsb pdb:6TG0|rcsb pdb:6TG1|rcsb pdb:6V5N|rcsb pdb:6V5P|rcsb pdb:6V66|rcsb pdb:6V6K|rcsb pdb:6V6O|rcsb pdb:6VH4|rcsb pdb:6VHN|rcsb pdb:6VHP|rcsb pdb:6WA2|rcsb pdb:6WAK|rcsb pdb:6WXN|rcsb pdb:6XL4|rcsb pdb:6Z4B|rcsb pdb:6Z4D|rcsb pdb:7A2A|rcsb pdb:7AEI|rcsb pdb:7AEM|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-1236394|reactome:R-HSA-1250196|reactome:R-HSA-1251932|reactome:R-HSA-1257604|reactome:R-HSA-177929|reactome:R-HSA-180292|reactome:R-HSA-180336|reactome:R-HSA-182971|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-212718|reactome:R-HSA-2179392|reactome:R-HSA-2219530|reactome:R-HSA-445144|reactome:R-HSA-5637810|reactome:R-HSA-5638303|reactome:R-HSA-5673001|reactome:R-HSA-6785631|reactome:R-HSA-6811558|reactome:R-HSA-8847993|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-179812|reactome:R-HSA-8857538|reactome:R-HSA-8863795|reactome:R-HSA-9009391|reactome:R-HSA-9013507|reactome:R-HSA-9609690|reactome:R-HSA-9634638|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-8866910|refseq:NP_005219.2|refseq:NP_958439.1|refseq:NP_958440.1|refseq:NP_958441.1|ensembl:ENSP00000275493|ensembl:ENST00000342916|ensembl:ENSP00000342376|ensembl:ENST00000344576|ensembl:ENSP00000345973|ensembl:ENST00000420316|ensembl:ENSP00000413843|dip:DIP-405N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:gXB5slVTC+z8DdqqXIzXG7lDwk09606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q04721 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-2652733|uniprotkb:Q5T3X7|uniprotkb:Q99734|uniprotkb:Q9H240|ensembl:ENSP00000256646 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:notc2_human(display_long)|uniprotkb:NOTCH2(gene name)|psi-mi:NOTCH2(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_001186930.1|refseq:NP_077719.2|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045967"(negative regulation of growth rate)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046849"(bone remodeling)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0061073"(ciliary body morphogenesis)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070986"(left/right axis specification)|go:"GO:0072014"(proximal tubule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0072104"(glomerular capillary formation)|go:"GO:0072574"(hepatocyte proliferation)|go:"GO:1990705"(cholangiocyte proliferation)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2001204"(regulation of osteoclast development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|go:"GO:0035622"(intrahepatic bile duct development)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022336|interpro:IPR010660(Notch, NOD region)|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|mint:Q04721|rcsb pdb:2OO4|rcsb pdb:5MWB|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-2197563|reactome:R-HSA-2979096|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013695|ensembl:ENSG00000134250(gene)|ensembl:ENST00000256646(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001709"(cell fate determination)|go:"GO:0001947"(heart looping)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0035264"(multicellular organism growth) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:aXdQSGMwNJ7K0tA2kc3rRFysbIc9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:P11717 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-1048580|uniprotkb:Q7Z7G9|uniprotkb:Q96PT5|ensembl:ENSP00000349437 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:mpri_human(display_long)|uniprotkb:Insulin-like growth factor 2 receptor(gene name synonym)|uniprotkb:Insulin-like growth factor II receptor(gene name synonym)|uniprotkb:M6P/IGF2 receptor(gene name synonym)|uniprotkb:300 kDa mannose 6-phosphate receptor(gene name synonym)|uniprotkb:IGF2R(gene name)|psi-mi:IGF2R(display_short)|uniprotkb:MPRI(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_000867.2|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005010"(insulin-like growth factor-activated receptor activity)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005537"(mannose binding)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|ensembl:ENSG00000197081(gene)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000356956(transcript)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0001889"(liver development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031995"(insulin-like growth factor II binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000479(Cation-independent mannose-6-phosphate receptor)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|interpro:IPR044865|mint:P11717|rcsb pdb:1E6F|rcsb pdb:1GP0|rcsb pdb:1GP3|rcsb pdb:1GQB|rcsb pdb:1JPL|rcsb pdb:1JWG|rcsb pdb:1LF8|rcsb pdb:2CNJ|rcsb pdb:2L29|rcsb pdb:2L2A|rcsb pdb:2M68|rcsb pdb:2M6T|rcsb pdb:2V5N|rcsb pdb:2V5O|rcsb pdb:2V5P|rcsb pdb:5IEI|rcsb pdb:6N5X|rcsb pdb:6N5Y|rcsb pdb:6P8I|rcsb pdb:6V02|rcsb pdb:6Z30|rcsb pdb:6Z31|rcsb pdb:6Z32|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|dip:DIP-6027N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:7lkG6WR8MQ/SONiTV/8g1ZTtKTU9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:P46531 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-636374|uniprotkb:Q59ED8|uniprotkb:Q5SXM3|intact:EBI-28989124|ensembl:ENSP00000498587 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:notc1_human(display_long)|uniprotkb:Translocation-associated notch protein TAN-1(gene name synonym)|uniprotkb:NOTCH1(gene name)|psi-mi:NOTCH1(display_short)|uniprotkb:TAN1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_060087.3|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006955"(immune response)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0005912"(adherens junction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007386"(compartment pattern specification)|go:"GO:0007411"(axon guidance)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021515"(cell differentiation in spinal cord)|go:"GO:0021915"(neural tube development)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035148"(tube formation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045608"(negative regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0045967"(negative regulation of growth rate)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060768"(regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0060842"(arterial endothelial cell differentiation)|go:"GO:0060843"(venous endothelial cell differentiation)|go:"GO:0060948"(cardiac vascular smooth muscle cell development)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:1901201"(regulation of extracellular matrix assembly)|go:"GO:0062043"(positive regulation of cardiac epithelial to mesenchymal transition)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:1902263"(apoptotic process involved in embryonic digit morphogenesis)|go:"GO:1902339"(positive regulation of apoptotic process involved in morphogenesis)|go:"GO:1903849"(positive regulation of aorta morphogenesis)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2000974"(negative regulation of pro-B cell differentiation)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|go:"GO:0070986"(left/right axis specification)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022362|interpro:IPR024600|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|interpro:IPR035993|interpro:IPR036770|mint:P46531|rcsb pdb:1PB5|rcsb pdb:1TOZ|rcsb pdb:1YYH|rcsb pdb:2F8X|rcsb pdb:2F8Y|rcsb pdb:2HE0|go:"GO:0072017"(distal tubule development)|go:"GO:0072044"(collecting duct development)|rcsb pdb:2VJ3|rcsb pdb:3ETO|rcsb pdb:3I08|rcsb pdb:3L95|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:4CUD|rcsb pdb:4CUE|rcsb pdb:4CUF|rcsb pdb:4D0E|rcsb pdb:4D0F|rcsb pdb:5FM9|rcsb pdb:5FMA|rcsb pdb:5KZO|rcsb pdb:5L0R|rcsb pdb:5UB5|rcsb pdb:6IDF|rcsb pdb:6PY8|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2660826|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|ensembl:ENSG00000148400(gene)|ensembl:ENST00000651671(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003157"(endocardium development)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003169"(coronary vein morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003182"(coronary sinus valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003192"(mitral valve formation)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003207"(cardiac chamber formation)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003209"(cardiac atrium morphogenesis)|go:"GO:0003213"(cardiac right atrium morphogenesis)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003219"(cardiac right ventricle formation)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003241"(growth involved in heart morphogenesis)|go:"GO:0003252"(negative regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003270"(Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0003273"(cell migration involved in endocardial cushion formation)|go:"GO:0003332"(negative regulation of extracellular matrix constituent secretion)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|dip:DIP-29919N|ensembl:ENSP00000498587 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:yRAjMjynnyZ7ANlk2eulodpS4P09606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:P04439 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-1042870|uniprotkb:O02963|uniprotkb:O78073|uniprotkb:P79563|uniprotkb:Q30208|uniprotkb:Q31623|uniprotkb:Q95377|uniprotkb:Q9BD15|uniprotkb:Q9BD19|uniprotkb:Q9MW42|uniprotkb:Q9TQK5|ensembl:ENSP00000366005|ensembl:ENSP00000379873|intact:EBI-1050524|intact:EBI-1049899|intact:EBI-2839447|intact:EBI-1044129|intact:EBI-8770309|intact:EBI-21249599|uniprotkb:B1PKZ3|uniprotkb:O02939|uniprotkb:O02954|uniprotkb:O02955|uniprotkb:O19509|uniprotkb:O19546|uniprotkb:O19598|uniprotkb:O19605|uniprotkb:O19606|uniprotkb:O19619|uniprotkb:O19647|uniprotkb:O19673|uniprotkb:O19687|uniprotkb:O19695|uniprotkb:O19756|uniprotkb:O19794|uniprotkb:O19795|uniprotkb:O43906|uniprotkb:O43907|uniprotkb:O46874|uniprotkb:O62921|uniprotkb:O62924|uniprotkb:O77937|uniprotkb:O77938|uniprotkb:O77964|uniprotkb:O78171|uniprotkb:O98009|uniprotkb:P30455|uniprotkb:P30456|uniprotkb:P30457|uniprotkb:P30458|uniprotkb:O98010|uniprotkb:O98011|uniprotkb:O98137|uniprotkb:P01891|uniprotkb:P01892|uniprotkb:P05534|uniprotkb:P06338|uniprotkb:P10313|uniprotkb:P10314|uniprotkb:P10315|uniprotkb:P10316|uniprotkb:P13746|uniprotkb:P16188|uniprotkb:P16189|uniprotkb:P16190|uniprotkb:P18462|uniprotkb:P30443|uniprotkb:P30444|uniprotkb:P30445|uniprotkb:P30446|uniprotkb:P30447|uniprotkb:P30448|uniprotkb:P30449|uniprotkb:P30450|uniprotkb:P30451|uniprotkb:P30514|uniprotkb:P79505|uniprotkb:P79562|uniprotkb:Q09160|uniprotkb:Q29680|uniprotkb:P30512|uniprotkb:Q29747|uniprotkb:Q29835|uniprotkb:Q29837|uniprotkb:Q29838|uniprotkb:Q29899|uniprotkb:Q29908|uniprotkb:Q29909|uniprotkb:Q29910|uniprotkb:Q5S3G1|uniprotkb:Q65A82|uniprotkb:Q8MHM1|uniprotkb:Q8MHN9|uniprotkb:Q95352|uniprotkb:Q95355|uniprotkb:P30452|uniprotkb:P30459|uniprotkb:Q95380|uniprotkb:Q95IZ5|uniprotkb:Q9BCN0|uniprotkb:Q9GJE6|uniprotkb:Q9GJE7|uniprotkb:Q9GJE8|uniprotkb:Q9MY89|uniprotkb:Q9MYA3|uniprotkb:Q9MYA5|uniprotkb:Q9MYC4|uniprotkb:Q9MYE6|uniprotkb:Q9MYE9|uniprotkb:Q9MYG4|uniprotkb:Q9MYG5|uniprotkb:Q9MYI5|uniprotkb:Q9TP25|uniprotkb:Q9TPQ3|uniprotkb:Q9TPR8|uniprotkb:Q9TPX8|uniprotkb:Q9TPX9|uniprotkb:Q9TPY0|uniprotkb:Q95362|uniprotkb:Q9TQ24|uniprotkb:Q9TQE8|uniprotkb:Q9TQE9|uniprotkb:Q9TQF1|uniprotkb:Q9TQF5|uniprotkb:Q9TQF8|uniprotkb:Q9TQF9|uniprotkb:Q9TQG0|uniprotkb:Q9TQG5|uniprotkb:Q9TQG7|uniprotkb:Q9TQH5|uniprotkb:Q9TQI3|uniprotkb:Q9TQM6|uniprotkb:Q9TQN5|uniprotkb:Q9TQP5|uniprotkb:Q9TQP6|uniprotkb:Q9TQP7|uniprotkb:Q9UIN1|uniprotkb:Q9UIN2|uniprotkb:Q9UIP7|uniprotkb:Q9UQU3|uniprotkb:Q9UQU6|uniprotkb:Q9UQU7|uniprotkb:P30453|uniprotkb:P30454|intact:EBI-1050350|intact:EBI-21505155 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:hlaa_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym)|uniprotkb:Human leukocyte antigen A(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303808|imex:IM-27647-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 ensembl:ENST00000376809(transcript)|ensembl:ENST00000396634(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002419"(T cell mediated cytotoxicity directed against tumor cell target)|go:"GO:0002485"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|ensembl:ENSG00000206503(gene)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016045"(detection of bacterium)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030881"(beta-2-microglobulin binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0036037"(CD8-positive, alpha-beta T cell activation)|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|go:"GO:0042590"(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0062061"(TAP complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000566"(positive regulation of CD8-positive, alpha-beta T cell proliferation)|go:"GO:2000568"(positive regulation of memory T cell activation)|go:"GO:2001187"(positive regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|go:"GO:0050830"(defense response to Gram-positive bacterium)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|mint:P04439|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1AQD|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UR7|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2C7U|rcsb pdb:2CLR|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2GIT|rcsb pdb:1P7Q|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1JF1|rcsb pdb:1JHT|rcsb pdb:1LP9|rcsb pdb:1OGA|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MGT|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MYJ|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3QZW|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3TO2|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:4E5X|rcsb pdb:4EMZ|rcsb pdb:4EN2|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MNQ|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4GKN|rcsb pdb:4NO5|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4OV5|rcsb pdb:4QOK|rcsb pdb:4U6X|rcsb pdb:4GKS|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4I48|rcsb pdb:4WJ5|rcsb pdb:4I4W|rcsb pdb:4WU5|rcsb pdb:4JFD|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4K7F|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQK|rcsb pdb:5SWQ|rcsb pdb:5TEZ|rcsb pdb:5W1W|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKF|rcsb pdb:5WKH|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT9|rcsb pdb:6D78|rcsb pdb:6D7G|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:5NME|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0C|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSD|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:6EWA|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-8866654|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:6RSY|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6ID4|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6MPP|rcsb pdb:6NCA|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:2GUO|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PYE|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2XPG|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3D25|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IXA|rcsb pdb:3KLA|rcsb pdb:3MGO|refseq:NP_002107.3|refseq:NP_001229687.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:RNvdwEiEB2h1Qfvd4BEIKiGzw1s9606 rigid:6YeQ0OtWJBnJ3zJjaRWxl37QCtc false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI5 uniprotkb:P54819 intact:EBI-22303849|ensemblbacteria:AAC67708|uniprotkb:O84119|uniprotkb:Q9RPP9 intact:EBI-1056291|uniprotkb:Q16856|uniprotkb:Q5TIF7|uniprotkb:Q8TCY2|uniprotkb:Q8TCY3|uniprotkb:A8K6L1|uniprotkb:B4DHH7|uniprotkb:B4DL64|uniprotkb:Q5EB54|ensembl:ENSP00000499935 psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name) psi-mi:kad2_human(display_long)|uniprotkb:AK2(gene name)|psi-mi:AK2(display_short)|uniprotkb:ADK2(gene name synonym)|uniprotkb:ATP-AMP transphosphorylase 2(gene name synonym)|uniprotkb:"ATP:AMP phosphotransferase"(gene name synonym)|uniprotkb:Adenylate monophosphate kinase(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303864|imex:IM-27647-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67708(transcript)|ensemblbacteria:CT_117(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|mint:P0DJI5|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119 refseq:NP_001186128.1|refseq:NP_001616.1|refseq:NP_037543.1|refseq:NP_001306068.1|refseq:NP_001306069.1|ensembl:ENSG00000004455(gene)|ensembl:ENST00000672715(transcript)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006172"(ADP biosynthetic process)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097226"(sperm mitochondrial sheath)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006259(Adenylate kinase, subfamily)|interpro:IPR007862(Adenylate kinase, zinc-finger lid region)|interpro:IPR027417|interpro:IPR028587|interpro:IPR033690|mint:P54819|rcsb pdb:2C9Y|reactome:R-HSA-499943 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561 rogid:pzIKBBzoytYPw3r87WMBueRNpWw9606 rigid:jCo/N8JOLDjkpDcKjNyDWduI9MA false binding-associated region:1-26|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI5 uniprotkb:Q06203 intact:EBI-22303849|ensemblbacteria:AAC67708|uniprotkb:O84119|uniprotkb:Q9RPP9 intact:EBI-3920254|ensembl:ENSP00000264220 psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name) psi-mi:pur1_human(display_long)|uniprotkb:PPAT(gene name)|psi-mi:PPAT(display_short)|uniprotkb:GPAT(gene name synonym)|uniprotkb:Glutamine phosphoribosylpyrophosphate amidotransferase(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303864|imex:IM-27647-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67708(transcript)|ensemblbacteria:CT_117(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|mint:P0DJI5|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119 ensembl:ENSG00000128059(gene)|ensembl:ENST00000264220(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001822"(kidney development)|go:"GO:0004044"(amidophosphoribosyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007595"(lactation)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0060135"(maternal process involved in female pregnancy)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005854(Amidophosphoribosyl transferase)|interpro:IPR017932|interpro:IPR029055|interpro:IPR029057|interpro:IPR035584|mint:Q06203|reactome:R-HSA-73817|refseq:NP_002694.3 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561 rogid:W+6JIL0Nlil+ZMhxjlmySnQkqZE9606 rigid:jCo/N8JOLDjkpDcKjNyDWduI9MA false binding-associated region:1-26|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI5 uniprotkb:P04632 intact:EBI-22303849|ensemblbacteria:AAC67708|uniprotkb:O84119|uniprotkb:Q9RPP9 intact:EBI-711828|uniprotkb:Q8WTX3|uniprotkb:Q96EW0|uniprotkb:A8K0P1|ensembl:ENSP00000246533|ensembl:ENSP00000464849 psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name) psi-mi:cpns1_human(display_long)|uniprotkb:Calcium-dependent protease small subunit 1(gene name synonym)|uniprotkb:Calcium-dependent protease small subunit(gene name synonym)|uniprotkb:Calpain regulatory subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase small subunit(gene name synonym)|uniprotkb:CAPNS1(gene name)|psi-mi:CAPNS1(display_short)|uniprotkb:CAPN4(gene name synonym)|uniprotkb:CAPNS(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303864|imex:IM-27647-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67708(transcript)|ensemblbacteria:CT_117(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|mint:P0DJI5|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119 ensembl:ENSG00000126247(gene)|ensembl:ENST00000246533(transcript)|ensembl:ENST00000588815(transcript)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR029642|mint:P04632|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:4PHJ|rcsb pdb:4PHK|rcsb pdb:4PHM|rcsb pdb:4WQ2|rcsb pdb:4WQ3|rcsb pdb:5D69|rcsb pdb:6QLB|reactome:R-HSA-1474228|reactome:R-HSA-6809371|reactome:R-HSA-8862803|refseq:NP_001003962.1|refseq:NP_001740.1|refseq:NP_001289561.1|refseq:NP_001289562.1|refseq:XP_005259352.1|refseq:XP_005259353.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561 rogid:siQugDvaWq0YjOr8qOCf0BsRRKs9606 rigid:jCo/N8JOLDjkpDcKjNyDWduI9MA false binding-associated region:1-26|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI5 uniprotkb:O75439 intact:EBI-22303849|ensemblbacteria:AAC67708|uniprotkb:O84119|uniprotkb:Q9RPP9 intact:EBI-721199|uniprotkb:O60416|uniprotkb:Q96FV4|ensembl:ENSP00000249269 psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name) psi-mi:mppb_human(display_long)|uniprotkb:Beta-MPP(gene name synonym)|uniprotkb:P-52(gene name synonym)|uniprotkb:PMPCB(gene name)|psi-mi:PMPCB(display_short)|uniprotkb:MPPB(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303864|imex:IM-27647-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67708(transcript)|ensemblbacteria:CT_117(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|mint:P0DJI5|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119 refseq:NP_004270.2|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0017087"(mitochondrial processing peptidase complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR037718|mint:O75439|reactome:R-HSA-1268020|reactome:R-HSA-8949664|ensembl:ENSG00000105819(gene)|ensembl:ENST00000249269(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561 rogid:TMqHDYssMbBpUdw0HcGrMPaJd/89606 rigid:jCo/N8JOLDjkpDcKjNyDWduI9MA false binding-associated region:1-26|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI5 uniprotkb:P17655 intact:EBI-22303849|ensemblbacteria:AAC67708|uniprotkb:O84119|uniprotkb:Q9RPP9 intact:EBI-1028956|uniprotkb:Q16738|uniprotkb:Q6PJT3|uniprotkb:Q8WU26|uniprotkb:Q9HBB1|uniprotkb:A6NDG7|ensembl:ENSP00000295006|uniprotkb:B7ZA96|uniprotkb:E7ES58 psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name) psi-mi:can2_human(display_long)|uniprotkb:CAPN2(gene name)|psi-mi:CAPN2(display_short)|uniprotkb:CANPL2(gene name synonym)|uniprotkb:Calpain-2 large subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 2(gene name synonym)|uniprotkb:Calpain M-type(gene name synonym)|uniprotkb:Millimolar-calpain(gene name synonym)|uniprotkb:Calpain large polypeptide L2(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303864|imex:IM-27647-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67708(transcript)|ensemblbacteria:CT_117(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|mint:P0DJI5|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119 refseq:NP_001139540.1|refseq:NP_001739.2|ensembl:ENSG00000162909(gene)|ensembl:ENST00000295006(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001824"(blastocyst development)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007565"(female pregnancy)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031143"(pseudopodium)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0005634"(nucleus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:2001247"(positive regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029539|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|interpro:IPR042736|mint:P17655|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:2NQA|reactome:R-HSA-1474228|reactome:R-HSA-8862803|interpro:IPR002048(Calcium-binding EF-hand) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561 rogid:r60XX66kihGVLaa9888soeXjc0M9606 rigid:jCo/N8JOLDjkpDcKjNyDWduI9MA false binding-associated region:1-26|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI5 uniprotkb:P02461 intact:EBI-22303849|ensemblbacteria:AAC67708|uniprotkb:O84119|uniprotkb:Q9RPP9 intact:EBI-2431491|uniprotkb:P78429|uniprotkb:Q15112|uniprotkb:Q9UC90|uniprotkb:Q9UC91|uniprotkb:Q16403|uniprotkb:Q53S91|uniprotkb:Q541P8|uniprotkb:Q6LDB3|uniprotkb:Q6LDJ2|uniprotkb:Q6LDJ3|uniprotkb:Q7KZ56|uniprotkb:Q8N6U4|uniprotkb:Q9UC88|uniprotkb:Q9UC89|uniprotkb:D2JYH5|uniprotkb:R4N3C5|uniprotkb:V9GZI1|uniprotkb:D3DPH4|ensembl:ENSP00000304408 psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name) psi-mi:co3a1_human(display_long)|uniprotkb:COL3A1(gene name)|psi-mi:COL3A1(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303864|imex:IM-27647-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67708(transcript)|ensemblbacteria:CT_117(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|mint:P0DJI5|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119 refseq:NP_000081.1|dip:DIP-57177N|ensembl:ENSG00000168542(gene)|ensembl:ENST00000304636(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0002020"(protease binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005586"(collagen type III trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0009314"(response to radiation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030168"(platelet activation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0034097"(response to cytokine)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0046872"(metal ion binding)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR008160(Collagen triple helix repeat)|mint:P02461|rcsb pdb:2V53|rcsb pdb:3DMW|rcsb pdb:4AE2|rcsb pdb:4AEJ|rcsb pdb:4AK3|rcsb pdb:4GYX|rcsb pdb:6FZV|rcsb pdb:6FZW|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-198933|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-419037|reactome:R-HSA-8874081|reactome:R-HSA-8948216 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561 rogid:mJwvNKDtUVF6OMwaeEO2xcjKYWE9606 rigid:jCo/N8JOLDjkpDcKjNyDWduI9MA false binding-associated region:1-26|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI5 uniprotkb:Q96KR6 intact:EBI-22303849|ensemblbacteria:AAC67708|uniprotkb:O84119|uniprotkb:Q9RPP9 intact:EBI-18938272|uniprotkb:B2RBQ9|uniprotkb:E1P5Y7|uniprotkb:Q8WVN2|uniprotkb:Q9BYL6|uniprotkb:Q9H418|ensembl:ENSP00000360437 psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name) psi-mi:f210b_human(display_long)|uniprotkb:FAM210B(gene name)|psi-mi:FAM210B(display_short)|uniprotkb:C20orf108(gene name synonym)|uniprotkb:PSEC0265(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303877|imex:IM-27647-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67708(transcript)|ensemblbacteria:CT_117(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|mint:P0DJI5|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119 refseq:NP_543011.2|ensembl:ENSG00000124098(gene)|ensembl:ENST00000371384(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR009688(Protein of unknown function DUF1279)|mint:Q96KR6 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561 rogid:UMQqeHBUt+7hAYbTA131Zkr/mxY9606 rigid:5niHQcpdaa2bLMOe/kbhzktOnvg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI5 uniprotkb:Q15058 intact:EBI-22303849|ensemblbacteria:AAC67708|uniprotkb:O84119|uniprotkb:Q9RPP9 intact:EBI-1045252|uniprotkb:Q14CI8|uniprotkb:Q4G0A5|uniprotkb:Q5T1W3|ensembl:ENSP00000356319|ensembl:ENSP00000483069 psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name) psi-mi:kif14_human(display_long)|uniprotkb:KIF14(gene name)|psi-mi:KIF14(display_short)|uniprotkb:KIAA0042(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303877|imex:IM-27647-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67708(transcript)|ensemblbacteria:CT_117(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|mint:P0DJI5|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119 refseq:NP_055690.1|ensembl:ENSG00000118193(gene)|ensembl:ENST00000367350(transcript)|ensembl:ENST00000614960(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021685"(cerebellar granular layer structural organization)|go:"GO:0021693"(cerebellar Purkinje cell layer structural organization)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032487"(regulation of Rap protein signal transduction)|go:"GO:0033624"(negative regulation of integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0090543"(Flemming body)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903429"(regulation of cell maturation)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|mint:Q15058|reactome:R-HSA-5625900|reactome:R-HSA-9696270|reactome:R-HSA-9696273|go:"GO:0021772"(olfactory bulb development)|refseq:NP_001292721.1|refseq:XP_011508533.1|refseq:XP_011508534.1|refseq:XP_016858494.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561 rogid:xIx+ywoBoaILDgAkmzxHOtF15DA9606 rigid:5niHQcpdaa2bLMOe/kbhzktOnvg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI5 uniprotkb:Q9BSJ2 intact:EBI-22303849|ensemblbacteria:AAC67708|uniprotkb:O84119|uniprotkb:Q9RPP9 intact:EBI-357881|uniprotkb:O43632|ensembl:ENSP00000252936|ensembl:ENSP00000506731|ensembl:ENSP00000507482|ensembl:ENSP00000507610|uniprotkb:Q5VWX7|uniprotkb:B4DM18|uniprotkb:F5H4E0|uniprotkb:B7ZKL8|uniprotkb:F5H4L0 psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name) psi-mi:gcp2_human(display_long)|uniprotkb:TUBGCP2(gene name)|psi-mi:TUBGCP2(display_short)|uniprotkb:GCP2(gene name synonym)|uniprotkb:Spindle pole body protein Spc97 homolog(gene name synonym)|uniprotkb:Gamma-ring complex protein 103 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303877|imex:IM-27647-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67708(transcript)|ensemblbacteria:CT_117(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|mint:P0DJI5|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119 refseq:NP_006650.1|ensembl:ENSG00000130640(gene)|ensembl:ENST00000252936(transcript)|ensembl:ENST00000682123(transcript)|ensembl:ENST00000682515(transcript)|ensembl:ENST00000683612(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0001764"(neuron migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001243547.1|refseq:NP_001243546.1|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007420"(brain development)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|mint:Q9BSJ2|rcsb pdb:6V6B|rcsb pdb:6V6S|rcsb pdb:6X0V|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561 rogid:vhamYv9ZNsZkSBkGQCwVylqx9wE9606 rigid:5niHQcpdaa2bLMOe/kbhzktOnvg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI5 uniprotkb:Q9UIA9 intact:EBI-22303849|ensemblbacteria:AAC67708|uniprotkb:O84119|uniprotkb:Q9RPP9 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303877|imex:IM-27647-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67708(transcript)|ensemblbacteria:CT_117(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|mint:P0DJI5|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119 refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:5niHQcpdaa2bLMOe/kbhzktOnvg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI5 uniprotkb:Q9NQC3 intact:EBI-22303849|ensemblbacteria:AAC67708|uniprotkb:O84119|uniprotkb:Q9RPP9 intact:EBI-715945|intact:EBI-1753019|uniprotkb:O94962|uniprotkb:Q9BXG5|uniprotkb:Q9H212|uniprotkb:Q9H3I3|uniprotkb:Q9UQ42|uniprotkb:Q9Y293|uniprotkb:Q9Y2Y7|uniprotkb:Q9Y5U6|intact:EBI-1958210|intact:EBI-1056082|uniprotkb:Q7L7Q8|uniprotkb:Q96B16|intact:EBI-28967519|ensembl:ENSP00000337838|uniprotkb:Q7L7Q5|uniprotkb:Q7L7Q6|uniprotkb:Q8IUA4 psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name) psi-mi:rtn4_human(display_long)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Foocen(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:Neuroendocrine-specific protein C homolog(gene name synonym)|uniprotkb:RTN-x(gene name synonym)|uniprotkb:Reticulon-5(gene name synonym)|uniprotkb:RTN4(gene name)|psi-mi:RTN4(display_short)|uniprotkb:KIAA0886(gene name synonym)|uniprotkb:NOGO(gene name synonym)|uniprotkb:My043(orf name)|uniprotkb:SP1507(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303877|imex:IM-27647-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67708(transcript)|ensemblbacteria:CT_117(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|mint:P0DJI5|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119 ensembl:ENST00000317610|ensembl:ENSP00000322147|ensembl:ENSP00000337838|ensembl:ENST00000357376|ensembl:ENSP00000349944|ensembl:ENST00000357732|ensembl:ENSP00000350365|ensembl:ENST00000394609|ensembl:ENSP00000378107|ensembl:ENST00000394611|ensembl:ENSP00000378109|ensembl:ENST00000404909|ensembl:ENSP00000385650|ensembl:ENST00000405240|ensembl:ENSP00000384471|refseq:NP_008939.1|refseq:NP_065393.1|refseq:NP_722550.1|refseq:NP_997403.1|refseq:NP_997404.1|ensembl:ENSG00000115310(gene)|ensembl:ENST00000337526(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021801"(cerebral cortex radial glia-guided migration)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035441"(cell migration involved in vasculogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:0120078"(cell adhesion involved in sprouting angiogenesis)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902624"(positive regulation of neutrophil migration)|go:"GO:1905523"(positive regulation of macrophage migration)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905580"(positive regulation of ERBB3 signaling pathway)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|go:"GO:2000172"(regulation of branching morphogenesis of a nerve)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001213"(negative regulation of vasculogenesis)|interpro:IPR003388(Reticulon)|mint:Q9NQC3|rcsb pdb:2G31|rcsb pdb:2JV5|reactome:R-HSA-193634|refseq:XP_005264491.1|refseq:NP_001308788.1|refseq:NP_001308789.1|refseq:NP_001308790.1|refseq:NP_001308791.1|refseq:NP_001308792.1|refseq:NP_001308833.1|refseq:XP_016860007.1|refseq:XP_016860008.1|dip:DIP-42003N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561 rogid:uhivTNOPdC7+q81CliY0Ozu0EwA9606 rigid:5niHQcpdaa2bLMOe/kbhzktOnvg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI5 uniprotkb:Q29RF7 intact:EBI-22303849|ensemblbacteria:AAC67708|uniprotkb:O84119|uniprotkb:Q9RPP9 intact:EBI-1175454|uniprotkb:Q2TTR5|uniprotkb:Q68DF7|uniprotkb:Q8N7J4|uniprotkb:Q8NG14|uniprotkb:Q9Y4D4|intact:EBI-2554552|ensembl:ENSP00000303427 psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name) psi-mi:pds5a_human(display_long)|uniprotkb:Sister chromatid cohesion protein 112(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 54 protein(gene name synonym)|uniprotkb:PDS5A(gene name)|psi-mi:PDS5A(display_short)|uniprotkb:KIAA0648(gene name synonym)|uniprotkb:PDS5(gene name synonym)|uniprotkb:PIG54(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303877|imex:IM-27647-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67708(transcript)|ensemblbacteria:CT_117(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|mint:P0DJI5|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119 ensembl:ENSG00000121892(gene)|ensembl:ENST00000303538(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039776|mint:Q29RF7|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|go:"GO:0005829"(cytosol)|refseq:NP_001093869.1|refseq:NP_001093870.1|refseq:XP_011511974.1|refseq:XP_016863417.1|dip:DIP-35419N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561 rogid:PaZZmQCIaSIoxVpMuuERQbDLMpY9606 rigid:5niHQcpdaa2bLMOe/kbhzktOnvg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NX20 uniprotkb:P0DPS6 intact:EBI-2560190|uniprotkb:Q9HB70|uniprotkb:Q9BYD0|ensembl:ENSP00000300151 intact:EBI-22303890|ensemblbacteria:AAC67709|uniprotkb:O84120|uniprotkb:Q9RPP8 psi-mi:rm16_human(display_long)|uniprotkb:MRPL16(gene name)|psi-mi:MRPL16(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL16m(gene name synonym)|uniprotkb:PNAS-111(orf name) psi-mi:incg_chltr(display_long)|uniprotkb:incG(gene name)|psi-mi:incG(display_short)|uniprotkb:CT_118(locus name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:272561(chltr)|taxid:272561(chltr) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-22303904|imex:IM-27647-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060310.1|ensembl:ENSG00000166902(gene)|ensembl:ENST00000300151(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0019843"(rRNA binding)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000114(Ribosomal protein L16)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR036920|mint:Q9NX20|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 ensemblbacteria:AAC67709(transcript)|ensemblbacteria:CT_118(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|mint:P0DPS6|refseq:NP_219621.1|refseq:WP_009871465.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:5ngQm8RUtN0SGgxJN2mGtWKhHMU9606 rogid:OcJqgIA74MSkXHwVH+wFDDj5T70272561 rigid:J9X92Yadt9aUVtd50HrxnixVMlA false - strep tag:c-c - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84569 uniprotkb:O60831 intact:EBI-22303910|ensemblbacteria:AAC68167 intact:EBI-2506064|ensembl:ENSP00000451962|uniprotkb:B2RD20 psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name) psi-mi:praf2_human(display_long)|uniprotkb:PRAF2(gene name)|psi-mi:PRAF2(display_short)|uniprotkb:JM4(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303917|imex:IM-27647-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68167(transcript)|ensemblbacteria:CT_565(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84569|refseq:NP_220080.1|refseq:WP_009871930.1 ensembl:ENSG00000243279(gene)|ensembl:ENST00000553851(transcript)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O60831|refseq:NP_009144.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561 rogid:ZCku1zr9TwPArrSO0aaKZlDsEyU9606 rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA false binding-associated region:1-144|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84569 uniprotkb:Q96HR9 intact:EBI-22303910|ensemblbacteria:AAC68167 intact:EBI-750345|uniprotkb:Q96LM0|uniprotkb:B2RE01|uniprotkb:A0A1L5BXV3|uniprotkb:D6W5Z0|ensembl:ENSP00000378861 psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name) psi-mi:reep6_human(display_long)|uniprotkb:Polyposis locus protein 1-like 1(gene name synonym)|uniprotkb:REEP6(gene name)|psi-mi:REEP6(display_short)|uniprotkb:C19orf32(gene name synonym)|uniprotkb:DP1L1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303917|imex:IM-27647-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68167(transcript)|ensemblbacteria:CT_565(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84569|refseq:NP_220080.1|refseq:WP_009871930.1 refseq:NP_612402.1|refseq:NP_001316485.1|ensembl:ENSG00000115255(gene)|ensembl:ENST00000395479(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|mint:Q96HR9|reactome:R-HSA-381753|go:"GO:0005634"(nucleus) - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561 rogid:pB8AjjNTpmaaLJ8j7MCBM45UAHE9606 rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA false binding-associated region:1-144|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84569 uniprotkb:P51572 intact:EBI-22303910|ensemblbacteria:AAC68167 intact:EBI-77683|ensembl:ENSP00000343458|ensembl:ENSP00000494052|ensembl:ENSP00000499882|uniprotkb:Q13836|uniprotkb:Q96CF0|uniprotkb:D3DWV5|uniprotkb:B3KQ79 psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name) psi-mi:bap31_human(display_long)|uniprotkb:BCAP31(gene name)|psi-mi:BCAP31(display_short)|uniprotkb:BAP31(gene name synonym)|uniprotkb:p28(gene name synonym)|uniprotkb:6C6-AG tumor-associated antigen(gene name synonym)|uniprotkb:DXS1357E(gene name synonym)|uniprotkb:Protein CDM(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303917|imex:IM-27647-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68167(transcript)|ensemblbacteria:CT_565(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84569|refseq:NP_220080.1|refseq:WP_009871930.1 refseq:NP_001132913.1|refseq:NP_005736.3|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904154"(positive regulation of retrograde protein transport, ER to cytosol)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR008417(B-cell receptor-associated 31-like)|interpro:IPR040463|interpro:IPR041672|mint:P51572|rcsb pdb:4JZL|rcsb pdb:4JZP|reactome:R-HSA-111465|reactome:R-HSA-75153|reactome:R-HSA-8980692|reactome:R-HSA-983170|ensembl:ENSG00000185825(gene)|ensembl:ENST00000345046(transcript)|ensembl:ENST00000647529(transcript)|ensembl:ENST00000672675(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044877"(protein-containing complex binding)|refseq:NP_001243376.1|refseq:NP_001132929.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561 rogid:m0aN00PLZJDWA/K1vEbla1W9+S89606 rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA false binding-associated region:1-144|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84569 uniprotkb:O15162 intact:EBI-22303910|ensemblbacteria:AAC68167 intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8 psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name) psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303917|imex:IM-27647-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68167(transcript)|ensemblbacteria:CT_565(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84569|refseq:NP_220080.1|refseq:WP_009871930.1 ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561 rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606 rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA false binding-associated region:1-144|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84569 uniprotkb:O14828 intact:EBI-22303910|ensemblbacteria:AAC68167 intact:EBI-4401333|ensembl:ENSP00000307275|ensembl:ENSP00000461521|uniprotkb:A9Z1W6|uniprotkb:B1AVS6|uniprotkb:O15128|uniprotkb:Q96FR8|uniprotkb:Q9BPY0 psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name) psi-mi:scam3_human(display_long)|uniprotkb:SCAMP3(gene name)|psi-mi:SCAMP3(display_short)|uniprotkb:C1orf3(gene name synonym)|uniprotkb:PROPIN1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303917|imex:IM-27647-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68167(transcript)|ensemblbacteria:CT_565(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84569|refseq:NP_220080.1|refseq:WP_009871930.1 ensembl:ENSG00000116521(gene)|ensembl:ENSG00000263290(gene)|ensembl:ENST00000302631(transcript)|ensembl:ENST00000570831(transcript)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007273(SCAMP)|mint:O14828|ensembl:ENSP00000307275|ensembl:ENST00000355379|ensembl:ENSP00000347540|ensembl:ENSP00000461521|ensembl:ENST00000573013|ensembl:ENSP00000458542|refseq:NP_005689.2|refseq:NP_443069.1 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561 rogid:q1GaoVa7cLS2hGHVUM5Nv2oX4x09606 rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA false binding-associated region:1-144|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84569 uniprotkb:Q99706 intact:EBI-22303910|ensemblbacteria:AAC68167 intact:EBI-10294579|uniprotkb:A8W795|uniprotkb:O43534|uniprotkb:P78400|uniprotkb:O14623|uniprotkb:Q99560|uniprotkb:O14621|uniprotkb:Q99561|uniprotkb:O14622|uniprotkb:P78401|uniprotkb:Q9UQJ7|uniprotkb:Q99562|uniprotkb:Q99559|uniprotkb:O14624|uniprotkb:Q8N738|ensembl:ENSP00000477886|ensembl:ENSP00000477887|ensembl:ENSP00000478362|ensembl:ENSP00000478491|ensembl:ENSP00000479179|ensembl:ENSP00000480801|ensembl:ENSP00000482206|ensembl:ENSP00000482383|ensembl:ENSP00000482452|ensembl:ENSP00000483101|ensembl:ENSP00000483782|ensembl:ENSP00000484389|ensembl:ENSP00000477601 psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name) psi-mi:ki2l4_human(display_long)|uniprotkb:KIR2DL4(gene name)|psi-mi:KIR2DL4(display_short)|uniprotkb:CD158 antigen-like family member D(gene name synonym)|uniprotkb:CD158D(gene name synonym)|uniprotkb:G9P(gene name synonym)|uniprotkb:KIR103AS(gene name synonym)|uniprotkb:Killer cell inhibitory receptor 103AS(gene name synonym)|uniprotkb:MHC class I NK cell receptor KIR103AS(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303917|imex:IM-27647-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68167(transcript)|ensemblbacteria:CT_565(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84569|refseq:NP_220080.1|refseq:WP_009871930.1 refseq:NP_002246.5|ensembl:ENSG00000274609(gene)|ensembl:ENSG00000274955(gene)|ensembl:ENSG00000275317(gene)|ensembl:ENSG00000275456(gene)|ensembl:ENSG00000276779(gene)|ensembl:ENSG00000277362(gene)|ensembl:ENSG00000277750(gene)|ensembl:ENSG00000277964(gene)|ensembl:ENSG00000278074(gene)|ensembl:ENSG00000278271(gene)|ensembl:ENSG00000278430(gene)|ensembl:ENST00000612573(transcript)|ensembl:ENST00000612660(transcript)|ensembl:ENST00000613053(transcript)|ensembl:ENST00000614653(transcript)|ensembl:ENST00000615970(transcript)|ensembl:ENST00000616354(transcript)|ensembl:ENST00000618297(transcript)|ensembl:ENST00000618358(transcript)|ensembl:ENST00000618567(transcript)|ensembl:ENST00000619637(transcript)|ensembl:ENST00000619848(transcript)|ensembl:ENST00000620484(transcript)|ensembl:ENST00000620486(transcript)|go:"GO:0002729"(positive regulation of natural killer cell cytokine production)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032394"(MHC class Ib receptor activity)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:Q99706|rcsb pdb:3WYR|reactome:R-HSA-198933 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561 rogid:wMAkL8jQLoP5FlMYL6zhLc8kuUI9606 rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA false binding-associated region:1-144|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84569 uniprotkb:Q6PIU2 intact:EBI-22303910|ensemblbacteria:AAC68167 intact:EBI-2907902|uniprotkb:B7Z2K4|uniprotkb:B7Z3A1|uniprotkb:B7Z5U2|uniprotkb:B7Z906|uniprotkb:B7ZAW6|uniprotkb:Q86WZ1|uniprotkb:Q9P2I4|uniprotkb:F5H7K4|ensembl:ENSP00000418571 psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name) psi-mi:nceh1_human(display_long)|uniprotkb:NCEH1(gene name)|psi-mi:NCEH1(display_short)|uniprotkb:AADACL1(gene name synonym)|uniprotkb:KIAA1363(gene name synonym)|uniprotkb:Arylacetamide deacetylase-like 1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303917|imex:IM-27647-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68167(transcript)|ensemblbacteria:CT_565(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84569|refseq:NP_220080.1|refseq:WP_009871930.1 refseq:NP_001139748.1|refseq:NP_001139749.1|refseq:NP_001139750.1|refseq:NP_065843.3|ensembl:ENSG00000144959(gene)|ensembl:ENST00000475381(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0046485"(ether lipid metabolic process)|go:"GO:0060395"(SMAD protein signal transduction)|interpro:IPR013094(Alpha/beta hydrolase fold-3)|interpro:IPR017157(Arylacetamide deacetylase)|interpro:IPR029058|interpro:IPR033140|mint:Q6PIU2|reactome:R-HSA-8964038 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561 rogid:ja3glDJZYcd7LadzVHDjBN8qncY9606 rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA false binding-associated region:1-144|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84569 uniprotkb:P38606 intact:EBI-22303910|ensemblbacteria:AAC68167 intact:EBI-1054757|intact:EBI-10982175|uniprotkb:Q53YD9|uniprotkb:Q96DY6|uniprotkb:Q9UHY3|uniprotkb:B2RBR8|uniprotkb:B7Z1R5|uniprotkb:D3DN75|ensembl:ENSP00000273398 psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name) psi-mi:vata_human(display_long)|uniprotkb:Vacuolar proton pump subunit alpha(gene name synonym)|uniprotkb:V-ATPase 69 kDa subunit(gene name synonym)|uniprotkb:Vacuolar ATPase isoform VA68(gene name synonym)|uniprotkb:ATP6V1A(gene name)|psi-mi:ATP6V1A(display_short)|uniprotkb:ATP6A1(gene name synonym)|uniprotkb:ATP6V1A1(gene name synonym)|uniprotkb:VPP2(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303917|imex:IM-27647-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68167(transcript)|ensemblbacteria:CT_565(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84569|refseq:NP_220080.1|refseq:WP_009871930.1 refseq:NP_001681.2|ensembl:ENSG00000114573(gene)|ensembl:ENST00000273398(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016469"(proton-transporting two-sector ATPase complex)|go:"GO:0030133"(transport vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:P38606|rcsb pdb:6WLZ|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561 rogid:GqPRFwsl5tDH83kpE8Al7NiYWrI9606 rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA false binding-associated region:1-144|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84569 uniprotkb:Q9NP73 intact:EBI-22303910|ensemblbacteria:AAC68167 intact:EBI-947892|uniprotkb:B1AKD6|uniprotkb:B1AKM1|uniprotkb:B2R5L5|uniprotkb:B7Z6J0|uniprotkb:B7Z804|uniprotkb:B7Z9A8|uniprotkb:B7ZAJ1|uniprotkb:B7ZB57|uniprotkb:Q9H5U8|uniprotkb:Q5JXY9|uniprotkb:Q17RC3|uniprotkb:B7Z847|ensembl:ENSP00000378260 psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name) psi-mi:alg13_human(display_long)|uniprotkb:ALG13(gene name)|psi-mi:ALG13(display_short)|uniprotkb:CXorf45(gene name synonym)|uniprotkb:Asparagine-linked glycosylation 13 homolog(gene name synonym)|uniprotkb:Glycosyltransferase 28 domain-containing protein 1(gene name synonym)|uniprotkb:UDP-N-acetylglucosamine transferase subunit ALG13 homolog(gene name synonym)|uniprotkb:MDS031(orf name)|uniprotkb:GLT28D1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303917|imex:IM-27647-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68167(transcript)|ensemblbacteria:CT_565(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84569|refseq:NP_220080.1|refseq:WP_009871930.1 refseq:NP_001034299.3|refseq:NP_001161857.1|refseq:NP_060936.1|refseq:NP_001244159.1|refseq:NP_001244160.1|refseq:NP_001244163.1|refseq:NP_001244166.1|refseq:NP_001093392.1|refseq:NP_001244170.1|ensembl:ENSG00000101901(gene)|ensembl:ENST00000394780(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004577"(N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005789"(endoplasmic reticulum membrane)|interpro:IPR002999(Tudor)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR007235(Glycosyl transferase, family 28, C-terminal)|interpro:IPR038765|mint:Q9NP73|reactome:R-HSA-446193|reactome:R-HSA-5633231 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561 rogid:IWuKvuIaEYMzcYT6dqoUr/1Uouc9606 rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA false binding-associated region:1-144|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84569 uniprotkb:O43504 intact:EBI-22303910|ensemblbacteria:AAC68167 intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439 psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name) psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303917|imex:IM-27647-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68167(transcript)|ensemblbacteria:CT_565(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84569|refseq:NP_220080.1|refseq:WP_009871930.1 refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561 rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606 rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA false binding-associated region:1-144|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O84569 uniprotkb:P01111 intact:EBI-22303910|ensemblbacteria:AAC68167 intact:EBI-721993|uniprotkb:Q14971|uniprotkb:Q15104|uniprotkb:Q15282|ensembl:ENSP00000358548 psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name) psi-mi:rasn_human(display_long)|uniprotkb:Transforming protein N-Ras(gene name synonym)|uniprotkb:NRAS(gene name)|psi-mi:NRAS(display_short)|uniprotkb:HRAS1(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303917|imex:IM-27647-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC68167(transcript)|ensemblbacteria:CT_565(gene)|go:"GO:0016021"(integral component of membrane)|mint:O84569|refseq:NP_220080.1|refseq:WP_009871930.1 refseq:NP_002515.1|ensembl:ENSG00000213281(gene)|ensembl:ENST00000369535(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|interpro:IPR001806(Ras GTPase)|dip:DIP-1058N|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|mint:P01111|rcsb pdb:2N9C|rcsb pdb:3CON|rcsb pdb:5UHV|rcsb pdb:6E6H|rcsb pdb:6MPP|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6WGH|rcsb pdb:6ZIO|rcsb pdb:6ZIR|rcsb pdb:6ZIZ|reactome:R-HSA-112412|reactome:R-HSA-1169092|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1433557|reactome:R-HSA-167044|reactome:R-HSA-171007|reactome:R-HSA-179812|reactome:R-HSA-180336|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-210993|reactome:R-HSA-2179392|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2871796|reactome:R-HSA-375165|reactome:R-HSA-442982|reactome:R-HSA-5218921|reactome:R-HSA-5621575|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654693|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5658442|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802953|reactome:R-HSA-6802955|reactome:R-HSA-74751|reactome:R-HSA-8849471|reactome:R-HSA-8851805|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9634635|reactome:R-HSA-9648002|reactome:R-HSA-9649913|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9703465|reactome:R-HSA-9703648 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561 rogid:Et90BD+t6LnYThbW6ShQge1GRK89606 rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA false binding-associated region:1-144|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI3 uniprotkb:P51784 intact:EBI-22303935|ensemblbacteria:AAC67706|uniprotkb:O84117|uniprotkb:Q9RPQ1 intact:EBI-306876|intact:EBI-1058416|uniprotkb:Q8IUG6|uniprotkb:Q9BWE1|uniprotkb:B2RTX1|ensembl:ENSP00000218348 psi-mi:incd_chltr(display_long)|uniprotkb:incD(gene name)|psi-mi:incD(display_short)|uniprotkb:CT_115(locus name) psi-mi:ubp11_human(display_long)|uniprotkb:USP11(gene name)|psi-mi:USP11(display_short)|uniprotkb:UHX1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 11(gene name synonym)|uniprotkb:Deubiquitinating enzyme 11(gene name synonym)|uniprotkb:Ubiquitin thioesterase 11(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303950|imex:IM-27647-79 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67706(transcript)|ensemblbacteria:CT_115(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|mint:P0DJI3|refseq:NP_219618.1|refseq:WP_009871462.1|interpro:IPR035117 ensembl:ENSG00000102226(gene)|ensembl:ENST00000218348(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:P51784|rcsb pdb:4MEL|rcsb pdb:5OK6|reactome:R-HSA-390471|reactome:R-HSA-5689880|refseq:NP_004642.2|refseq:XP_011542290.1|refseq:XP_005272731.1|dip:DIP-27567N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:NtfH41PBF6GvaI2uBjbJOl4Jsic272561 rogid:OSJLLFBf1ofw8SC01p2iiIM1oJo9606 rigid:fVRhYpL/aEJTZ/fK0GVaHKB2f7s false binding-associated region:95-141|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI3 uniprotkb:P33176 intact:EBI-22303935|ensemblbacteria:AAC67706|uniprotkb:O84117|uniprotkb:Q9RPQ1 intact:EBI-355878|uniprotkb:A0AVB2|uniprotkb:Q5VZ85|ensembl:ENSP00000307078 psi-mi:incd_chltr(display_long)|uniprotkb:incD(gene name)|psi-mi:incD(display_short)|uniprotkb:CT_115(locus name) psi-mi:kinh_human(display_long)|uniprotkb:KIF5B(gene name)|psi-mi:KIF5B(display_short)|uniprotkb:KNS(gene name synonym)|uniprotkb:KNS1(gene name synonym)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303950|imex:IM-27647-79 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67706(transcript)|ensemblbacteria:CT_115(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|mint:P0DJI3|refseq:NP_219618.1|refseq:WP_009871462.1|interpro:IPR035117 refseq:NP_004512.1|ensembl:ENSG00000170759(gene)|ensembl:ENST00000302418(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016020"(membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031982"(vesicle)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032418"(lysosome localization)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099609"(microtubule lateral binding)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905152"(positive regulation of voltage-gated sodium channel activity)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:P33176|rcsb pdb:1BG2|rcsb pdb:1MKJ|rcsb pdb:2P4N|rcsb pdb:3J8X|rcsb pdb:3J8Y|rcsb pdb:4HNA|rcsb pdb:4LNU|rcsb pdb:5LT0|rcsb pdb:5LT1|rcsb pdb:5LT2|rcsb pdb:5LT3|rcsb pdb:5LT4|rcsb pdb:6OJQ|reactome:R-HSA-2132295|reactome:R-HSA-264876|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-983189|dip:DIP-29244N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:NtfH41PBF6GvaI2uBjbJOl4Jsic272561 rogid:2UUVZBn5EAd0xBA5IZDPWHX9i7U9606 rigid:fVRhYpL/aEJTZ/fK0GVaHKB2f7s false binding-associated region:95-141|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI3 uniprotkb:Q14315 intact:EBI-22303935|ensemblbacteria:AAC67706|uniprotkb:O84117|uniprotkb:Q9RPQ1 intact:EBI-489954|uniprotkb:O95303|uniprotkb:Q07985|uniprotkb:Q9NS12|uniprotkb:Q9NYE5|uniprotkb:Q9UMR8|uniprotkb:Q9Y503|uniprotkb:B2ZZ88|ensembl:ENSP00000327145 psi-mi:incd_chltr(display_long)|uniprotkb:incD(gene name)|psi-mi:incD(display_short)|uniprotkb:CT_115(locus name) psi-mi:flnc_human(display_long)|uniprotkb:Filamin-2(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:ABP-L(gene name synonym)|uniprotkb:ABP-280-like protein(gene name synonym)|uniprotkb:Gamma-filamin(gene name synonym)|uniprotkb:FLNC(gene name)|psi-mi:FLNC(display_short)|uniprotkb:ABPL(gene name synonym)|uniprotkb:FLN2(gene name synonym) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303950|imex:IM-27647-79 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67706(transcript)|ensemblbacteria:CT_115(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|mint:P0DJI3|refseq:NP_219618.1|refseq:WP_009871462.1|interpro:IPR035117 refseq:NP_001120959.1|refseq:NP_001449.3|ensembl:ENSG00000128591(gene)|ensembl:ENST00000325888(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:Q14315|rcsb pdb:1V05|rcsb pdb:2D7M|rcsb pdb:2D7N|rcsb pdb:2D7O|rcsb pdb:2D7P|rcsb pdb:2D7Q|rcsb pdb:2K9U|rcsb pdb:2NQC|rcsb pdb:3V8O|rcsb pdb:4MGX|reactome:R-HSA-446353|dip:DIP-33398N - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:NtfH41PBF6GvaI2uBjbJOl4Jsic272561 rogid:sBGhjObBECicoAu/8T5lDIt1ToY9606 rigid:fVRhYpL/aEJTZ/fK0GVaHKB2f7s false binding-associated region:95-141|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5P4 uniprotkb:P0DJI3 intact:EBI-739994|uniprotkb:Q96Q85|uniprotkb:Q96Q88|uniprotkb:Q9H2S7|uniprotkb:Q9H2S8|uniprotkb:Q53YV1|uniprotkb:Q53YV2|uniprotkb:A8K7S2|uniprotkb:B3KUB7|ensembl:ENSP00000261415|ensembl:ENSP00000494110|ensembl:ENSP00000495760 intact:EBI-22303935|ensemblbacteria:AAC67706|uniprotkb:O84117|uniprotkb:Q9RPQ1 psi-mi:cert_human(display_long)|uniprotkb:CERT1(gene name)|psi-mi:CERT1(display_short)|uniprotkb:CERT(gene name synonym)|uniprotkb:COL4A3BP(gene name synonym)|uniprotkb:Collagen type IV alpha-3-binding protein(gene name synonym)|uniprotkb:Goodpasture antigen-binding protein(gene name synonym)|uniprotkb:STARD11(gene name synonym)|uniprotkb:START domain-containing protein 11(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 11(gene name synonym) psi-mi:incd_chltr(display_long)|uniprotkb:incD(gene name)|psi-mi:incD(display_short)|uniprotkb:CT_115(locus name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:272561(chltr)|taxid:272561(chltr) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-22303961|imex:IM-27647-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123577.1|refseq:NP_005704.1|refseq:NP_112729.1|refseq:XP_016864408.1|rcsb pdb:2E3P|rcsb pdb:2E3Q|rcsb pdb:2E3R|rcsb pdb:2E3S|rcsb pdb:2RSG|rcsb pdb:2Z9Y|rcsb pdb:2Z9Z|rcsb pdb:3H3Q|rcsb pdb:3H3R|rcsb pdb:3H3S|rcsb pdb:3H3T|rcsb pdb:4HHV|rcsb pdb:5JJD|rcsb pdb:5ZYG|rcsb pdb:5ZYH|rcsb pdb:5ZYI|rcsb pdb:5ZYJ|rcsb pdb:5ZYK|rcsb pdb:5ZYL|rcsb pdb:5ZYM|rcsb pdb:6IEZ|rcsb pdb:6IF0|rcsb pdb:6J0O|rcsb pdb:6J81|reactome:R-HSA-1660661|ensembl:ENSG00000113163(gene)|ensembl:ENST00000261415(transcript)|ensembl:ENST00000643780(transcript)|ensembl:ENST00000644072(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0006955"(immune response)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0035627"(ceramide transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0097001"(ceramide binding)|go:"GO:0120009"(intermembrane lipid transfer)|go:"GO:0120012"(intermembrane sphingolipid transfer)|go:"GO:0120017"(ceramide transfer activity)|go:"GO:1902387"(ceramide 1-phosphate binding)|go:"GO:1902388"(ceramide 1-phosphate transfer activity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002913(Lipid-binding START)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023393|interpro:IPR041952|mint:Q9Y5P4|rcsb pdb:2E3M|rcsb pdb:2E3N|rcsb pdb:2E3O|refseq:XP_006714576.1 ensemblbacteria:AAC67706(transcript)|ensemblbacteria:CT_115(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|mint:P0DJI3|refseq:NP_219618.1|refseq:WP_009871462.1|interpro:IPR035117 - - - figure legend:F1 ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/12 rogid:AohUpOJQHInz8f5bKv9/Xb5K+/Y9606 rogid:NtfH41PBF6GvaI2uBjbJOl4Jsic272561 rigid:G71pXxjDJJPuwCHlwYhluW+eybs false - strep tag:c-c - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DJI4 uniprotkb:Q9UNH7 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-949294|ensembl:ENSP00000355217|uniprotkb:Q9Y449|uniprotkb:C0H5W9 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25295488|imex:IM-27647-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 ensembl:ENSG00000129515(gene)|ensembl:ENST00000362031(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097422"(tubular endosome)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0016241"(regulation of macroautophagy)|interpro:IPR028657|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030904"(retromer complex)|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|go:"GO:0030905"(retromer, tubulation complex)|refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N - - - figure legend:f4a f4e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/16 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606 rigid:goeedF/tULz346QqYmty980UmZQ false strep tag:c-c|sufficient binding region:101-132 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0DJI4 uniprotkb:Q9Y5X3 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-715760|uniprotkb:Q52LC4|uniprotkb:B7ZKN3|uniprotkb:Q9BWP0|uniprotkb:Q7KZN0|uniprotkb:D3DW26|ensembl:ENSP00000366988|ensembl:ENSP00000366998 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:snx5_human(display_long)|uniprotkb:SNX5(gene name)|psi-mi:SNX5(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25295488|imex:IM-27647-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_055241.1|refseq:NP_689413.1|ensembl:ENSG00000089006(gene)|ensembl:ENST00000377759(transcript)|ensembl:ENST00000377768(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006907"(pinocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070685"(macropinocytic cup)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097422"(tubular endosome)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028654|interpro:IPR036871|interpro:IPR042135|mint:Q9Y5X3|rcsb pdb:1SYS|rcsb pdb:5TGH|rcsb pdb:5TGI|rcsb pdb:5TGJ|rcsb pdb:5WY2|rcsb pdb:6N5X|rcsb pdb:6N5Y|rcsb pdb:6N5Z|reactome:R-HSA-432722 - - - figure legend:f4a f4e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/16 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:VR2oUxQ4M2bm5zKeHQlao046QL09606 rigid:goeedF/tULz346QqYmty980UmZQ false strep tag:c-c|sufficient binding region:101-132 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0DJI4 uniprotkb:O60749 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-1046690|uniprotkb:O43650|uniprotkb:P82862|uniprotkb:Q53XK8|uniprotkb:Q597H6|uniprotkb:Q9BTS8|ensembl:ENSP00000368831|uniprotkb:B3KN44|uniprotkb:B4DEK4|uniprotkb:B7Z408 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:snx2_human(display_long)|uniprotkb:Transformation-related gene 9 protein(gene name synonym)|uniprotkb:SNX2(gene name)|psi-mi:SNX2(display_short)|uniprotkb:TRG9(orf name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25295488|imex:IM-27647-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_003091.2|ensembl:ENSG00000205302(gene)|ensembl:ENST00000379516(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028653|interpro:IPR037918|mint:O60749|interpro:IPR036871|reactome:R-HSA-432722|refseq:NP_001265128.1 - - - figure legend:f4a f4e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/16 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:Sb/i4ZNGqy+ixeexnp0/4uOo3jo9606 rigid:goeedF/tULz346QqYmty980UmZQ false strep tag:c-c|sufficient binding region:101-132 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0DJI4 uniprotkb:Q13596 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25295488|imex:IM-27647-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528(gene)|ensembl:ENST00000559844(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|interpro:IPR036871|dip:DIP-398N - - - figure legend:f4a f4e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/12/11 2019/12/16 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606 rigid:goeedF/tULz346QqYmty980UmZQ false strep tag:c-c|sufficient binding region:101-132 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0DJI4 uniprotkb:Q9D8U8 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-643385|uniprotkb:Q543N9|ensembl:ENSMUSP00000028909|ensembl:ENSMUSP00000105657 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:snx5_mouse(display_long)|uniprotkb:Snx5(gene name)|psi-mi:Snx5(display_short) psi-mi:"MI:0663"(confocal microscopy) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-25398962|imex:IM-27647-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_001186117.1|refseq:NP_077187.1|ensembl:ENSMUST00000110030(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006907"(pinocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0030904"(retromer complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070685"(macropinocytic cup)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097422"(tubular endosome)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028654|interpro:IPR036871|mint:Q9D8U8|rcsb pdb:5TP1|reactome:R-MMU-432722|ensembl:ENSMUST00000028909(transcript)|ensembl:ENSMUSG00000027423(gene) - - - figure legend:sf4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2019/12/11 2020/01/30 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:fQ84XvM7jLdmmQr00Afs3oaAUBI10090 rigid:Yfyd0hSpTk0vp6QxTT2jei5zPjg false green fluorescent protein tag:c-c|binding-associated region:101-132 flag tag:n-n - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:P0DJI4 uniprotkb:Q9UNH7 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-949294|ensembl:ENSP00000355217|uniprotkb:Q9Y449|uniprotkb:C0H5W9 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short) psi-mi:"MI:0663"(confocal microscopy) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-25398962|imex:IM-27647-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 ensembl:ENSG00000129515(gene)|ensembl:ENST00000362031(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097422"(tubular endosome)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0016241"(regulation of macroautophagy)|interpro:IPR028657|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030904"(retromer complex)|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|go:"GO:0030905"(retromer, tubulation complex)|refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N - - - figure legend:sf4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2019/12/11 2020/01/30 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606 rigid:Yfyd0hSpTk0vp6QxTT2jei5zPjg false green fluorescent protein tag:c-c|binding-associated region:101-132 - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q9D8U8 uniprotkb:P0DJI4 intact:EBI-643385|uniprotkb:Q543N9|ensembl:ENSMUSP00000028909|ensembl:ENSMUSP00000105657 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 psi-mi:snx5_mouse(display_long)|uniprotkb:Snx5(gene name)|psi-mi:Snx5(display_short) psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:"MI:0663"(confocal microscopy) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:272561(chltr)|taxid:272561(chltr) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-25398995|imex:IM-27647-103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186117.1|refseq:NP_077187.1|ensembl:ENSMUST00000110030(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006907"(pinocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0030904"(retromer complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070685"(macropinocytic cup)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097422"(tubular endosome)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028654|interpro:IPR036871|mint:Q9D8U8|rcsb pdb:5TP1|reactome:R-MMU-432722|ensembl:ENSMUST00000028909(transcript)|ensembl:ENSMUSG00000027423(gene) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 - - - figure legend:F5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2019/12/11 2020/01/30 rogid:fQ84XvM7jLdmmQr00Afs3oaAUBI10090 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rigid:yBnG0GtX/J0gGCUqumuSOAlZzgE false flag tag:n-n - - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:P0DJI4 uniprotkb:Q13596 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short) psi-mi:"MI:0663"(confocal microscopy) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-25399045|imex:IM-27647-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528(gene)|ensembl:ENST00000559844(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|interpro:IPR036871|dip:DIP-398N - - - figure legend:f5A sf5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2019/12/11 2020/01/16 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606 rigid:++zQa8MUHWr8nGOCytSEDVBE05Y false - - - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:P0DJI4 uniprotkb:Q9UNH7 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-949294|ensembl:ENSP00000355217|uniprotkb:Q9Y449|uniprotkb:C0H5W9 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short) psi-mi:"MI:0663"(confocal microscopy) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-25399063|imex:IM-27647-99 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 ensembl:ENSG00000129515(gene)|ensembl:ENST00000362031(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097422"(tubular endosome)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0016241"(regulation of macroautophagy)|interpro:IPR028657|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030904"(retromer complex)|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|go:"GO:0030905"(retromer, tubulation complex)|refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N - - - figure legend:f5A sf5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2019/12/11 2020/01/16 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606 rigid:Wy+bfvkLXGLqC6/EzHLcEoZnLis false - - - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:P0DJI4 uniprotkb:O60749 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-1046690|uniprotkb:O43650|uniprotkb:P82862|uniprotkb:Q53XK8|uniprotkb:Q597H6|uniprotkb:Q9BTS8|ensembl:ENSP00000368831|uniprotkb:B3KN44|uniprotkb:B4DEK4|uniprotkb:B7Z408 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:snx2_human(display_long)|uniprotkb:Transformation-related gene 9 protein(gene name synonym)|uniprotkb:SNX2(gene name)|psi-mi:SNX2(display_short)|uniprotkb:TRG9(orf name) psi-mi:"MI:0663"(confocal microscopy) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-25399069|imex:IM-27647-105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_003091.2|ensembl:ENSG00000205302(gene)|ensembl:ENST00000379516(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028653|interpro:IPR037918|mint:O60749|interpro:IPR036871|reactome:R-HSA-432722|refseq:NP_001265128.1 - - - figure legend:F5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2019/12/11 2020/01/16 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:Sb/i4ZNGqy+ixeexnp0/4uOo3jo9606 rigid:RzvDLRdyMbl06IH3oRPXp5wGyRI false - - - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:P0DJI4 uniprotkb:P0CI27 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-22303749|ensemblbacteria:AAC67710|uniprotkb:O84121|uniprotkb:Q99Q56|uniprotkb:Q9AM94|uniprotkb:Q9AMA7|uniprotkb:Q9AMA8|uniprotkb:Q9AMA9|uniprotkb:Q9AMB0|uniprotkb:Q9AMB1|uniprotkb:Q9F7K9|uniprotkb:Q9RFX7 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:inca_chltr(display_long)|uniprotkb:incA(gene name)|psi-mi:incA(display_short)|uniprotkb:CT_119(locus name) psi-mi:"MI:0663"(confocal microscopy) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:272561(chltr)|taxid:272561(chltr) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-25399096|imex:IM-27647-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 ensemblbacteria:AAC67710(transcript)|ensemblbacteria:CT_119(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:6E6A|rcsb pdb:6E7E|go:"GO:0005576"(extracellular region)|mint:P0CI27|refseq:NP_219622.1|refseq:WP_009871466.1 - - - figure legend:sf5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2019/12/11 2020/01/16 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:ccmWavz7ZW1HZZFFu1T5BVIQLVs272561 rigid:+73Zz6tnsoUICDGSETMIiZc4CW0 false - - - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:P0DJI4 uniprotkb:Q13596 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short) psi-mi:"MI:0663"(confocal microscopy) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-25420698|imex:IM-27647-106 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528(gene)|ensembl:ENST00000559844(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|interpro:IPR036871|dip:DIP-398N - - - figure legend:sf5b sf5c|agonist:nocodazole|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2019/12/11 2020/01/30 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606 rigid:PQjFWtLLO9dNhWl9Pl/yEiBYflw false - - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:P0DJI4 uniprotkb:Q9UNH7 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 intact:EBI-949294|ensembl:ENSP00000355217|uniprotkb:Q9Y449|uniprotkb:C0H5W9 psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short) psi-mi:"MI:0663"(confocal microscopy) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:272561(chltr)|taxid:272561(chltr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-25420698|imex:IM-27647-106 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 ensembl:ENSG00000129515(gene)|ensembl:ENST00000362031(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097422"(tubular endosome)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0016241"(regulation of macroautophagy)|interpro:IPR028657|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030904"(retromer complex)|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|go:"GO:0030905"(retromer, tubulation complex)|refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N - - - figure legend:sf5b sf5c|agonist:nocodazole|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2019/12/11 2020/01/30 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606 rigid:PQjFWtLLO9dNhWl9Pl/yEiBYflw false - - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:B0B9M4 uniprotkb:Q9UNH7 intact:EBI-25421041|uniprotkb:O84118|uniprotkb:Q9RPQ0|ensemblbacteria:CAP03811 intact:EBI-949294|ensembl:ENSP00000355217|uniprotkb:Q9Y449|uniprotkb:C0H5W9 psi-mi:ince_chlt2(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CTL0371(locus name) psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short) psi-mi:"MI:0663"(confocal microscopy) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:471472(chlt2)|taxid:471472("Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-25421035|imex:IM-27647-108 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_009873571.1|refseq:YP_001654455.1|interpro:IPR035118|mint:B0B9M4|ensemblbacteria:CAP03811(transcript)|ensemblbacteria:CTL0371(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane) ensembl:ENSG00000129515(gene)|ensembl:ENST00000362031(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097422"(tubular endosome)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0016241"(regulation of macroautophagy)|interpro:IPR028657|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030904"(retromer complex)|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|go:"GO:0030905"(retromer, tubulation complex)|refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N - - - figure legend:f6d f6e|comment:"We also observed increased SNX6 recruitment and SNX6-positive tubules in C. trachomatis serovar L2 transformed with a vector expressing untagged IncE (pIncE) under control of its native promoter compared to C. trachomatis transformed with empty vector (Figure 6D and 6E)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2019/12/11 2020/01/31 rogid:KeYDCr/BYZ31n0CMgSzemsUUpec471472 rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606 rigid:yB0e2S7kowOd2qGl8eo9dqsvLwM false - - - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q9UNH7 uniprotkb:P0DJI4 intact:EBI-949294|ensembl:ENSP00000355217|uniprotkb:Q9Y449|uniprotkb:C0H5W9 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short) psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:272561(chltr)|taxid:272561(chltr) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-25398684|imex:IM-27647-95 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000129515(gene)|ensembl:ENST00000362031(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097422"(tubular endosome)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0016241"(regulation of macroautophagy)|interpro:IPR028657|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030904"(retromer complex)|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|go:"GO:0030905"(retromer, tubulation complex)|refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 - - - figure legend:f4f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/11 2020/01/30 rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rigid:Wy+bfvkLXGLqC6/EzHLcEoZnLis false his tag:n-n|binding-associated region:1-181 tandem tag:?-?|binding-associated region:101-132|strep tag:c-c - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9D8U8 uniprotkb:P0DJI4 intact:EBI-643385|uniprotkb:Q543N9|ensembl:ENSMUSP00000028909|ensembl:ENSMUSP00000105657 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 psi-mi:snx5_mouse(display_long)|uniprotkb:Snx5(gene name)|psi-mi:Snx5(display_short) psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:"MI:0096"(pull down) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:272561(chltr)|taxid:272561(chltr) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-25398758|imex:IM-27647-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186117.1|refseq:NP_077187.1|ensembl:ENSMUST00000110030(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006907"(pinocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0030904"(retromer complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070685"(macropinocytic cup)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097422"(tubular endosome)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028654|interpro:IPR036871|mint:Q9D8U8|rcsb pdb:5TP1|reactome:R-MMU-432722|ensembl:ENSMUST00000028909(transcript)|ensembl:ENSMUSG00000027423(gene) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 - - - figure legend:f4f sf4f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/11 2020/01/30 rogid:fQ84XvM7jLdmmQr00Afs3oaAUBI10090 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rigid:yBnG0GtX/J0gGCUqumuSOAlZzgE false his tag:n-n|necessary binding region:1-195 tandem tag:?-?|sufficient binding region:108-132|strep tag:c-c - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9UNH7 uniprotkb:P0DJI4 intact:EBI-949294|ensembl:ENSP00000355217|uniprotkb:Q9Y449|uniprotkb:C0H5W9 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short) psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:272561(chltr)|taxid:272561(chltr) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25398676|imex:IM-27647-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000129515(gene)|ensembl:ENST00000362031(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097422"(tubular endosome)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0016241"(regulation of macroautophagy)|interpro:IPR028657|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030904"(retromer complex)|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|go:"GO:0030905"(retromer, tubulation complex)|refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 - - - figure legend:f4b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2019/12/11 2020/01/16 rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rigid:Wy+bfvkLXGLqC6/EzHLcEoZnLis false - strep tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9D8U8 uniprotkb:P0DJI4 intact:EBI-643385|uniprotkb:Q543N9|ensembl:ENSMUSP00000028909|ensembl:ENSMUSP00000105657 intact:EBI-22303778|ensemblbacteria:AAC67707|uniprotkb:O84118|uniprotkb:Q9RPQ0 psi-mi:snx5_mouse(display_long)|uniprotkb:Snx5(gene name)|psi-mi:Snx5(display_short) psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mirrashidi et al. (2015) pubmed:26118995|imex:IM-27647 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:272561(chltr)|taxid:272561(chltr) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25398774|imex:IM-27647-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186117.1|refseq:NP_077187.1|ensembl:ENSMUST00000110030(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006907"(pinocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0030904"(retromer complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070685"(macropinocytic cup)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097422"(tubular endosome)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028654|interpro:IPR036871|mint:Q9D8U8|rcsb pdb:5TP1|reactome:R-MMU-432722|ensembl:ENSMUST00000028909(transcript)|ensembl:ENSMUSG00000027423(gene) ensemblbacteria:AAC67707(transcript)|ensemblbacteria:CT_116(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0140221"(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|mint:P0DJI4|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118 - - - figure legend:f4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2019/12/11 2020/01/30 rogid:fQ84XvM7jLdmmQr00Afs3oaAUBI10090 rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561 rigid:yBnG0GtX/J0gGCUqumuSOAlZzgE false flag tag:n-n strep tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)