#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q6NUD0	uniprotkb:Q6NUA1	intact:EBI-21229433	intact:EBI-21229405	psi-mi:mep50_xenla(display_long)|uniprotkb:WD repeat-containing protein 77(gene name synonym)|uniprotkb:wdr77(gene name)|psi-mi:wdr77(display_short)|uniprotkb:mep50(gene name synonym)	psi-mi:anm5_xenla(display_long)|uniprotkb:Histone synthetic lethal 7 protein(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT5(gene name synonym)|uniprotkb:prmt5(gene name)|psi-mi:prmt5(display_short)|uniprotkb:hsl7(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Ho et al. (2012)	pubmed:23451136|imex:IM-27220	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-21229403|wwpdb:4G56|imex:IM-27220-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001084703.1|rcsb pdb:4G56|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|go:"GO:0005829"(cytosol)|go:"GO:0034709"(methylosome)|go:"GO:0035097"(histone methyltransferase complex)	refseq:NP_001084480.1|rcsb pdb:4G56|interpro:IPR025799|interpro:IPR007857(Skb1 methyltransferase)|interpro:IPR035075|interpro:IPR035248|interpro:IPR035247|interpro:IPR029063|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0034709"(methylosome)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0051301"(cell division)|go:"GO:0070888"(E-box binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)	-	-	-	figure legend:Fig. 1, Tab.1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2019/03/06	2019/03/06	rogid:EhupNycgSXZAXxK7wdMWmetWxE48355	rogid:WkUcg9FeSOXhO7okiQs6tPTiHU08355	rigid:UA3MfRYvEitIi6woG4WvQvxxU18	false	his tag:n-n	his tag:n-n	4	4	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q6NUD0	uniprotkb:Q6NUA1	intact:EBI-21229433	intact:EBI-21229405	psi-mi:mep50_xenla(display_long)|uniprotkb:WD repeat-containing protein 77(gene name synonym)|uniprotkb:wdr77(gene name)|psi-mi:wdr77(display_short)|uniprotkb:mep50(gene name synonym)	psi-mi:anm5_xenla(display_long)|uniprotkb:Histone synthetic lethal 7 protein(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT5(gene name synonym)|uniprotkb:prmt5(gene name)|psi-mi:prmt5(display_short)|uniprotkb:hsl7(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Ho et al. (2012)	pubmed:23451136|imex:IM-27220	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-21229507|imex:IM-27220-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001084703.1|rcsb pdb:4G56|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|go:"GO:0005829"(cytosol)|go:"GO:0034709"(methylosome)|go:"GO:0035097"(histone methyltransferase complex)	refseq:NP_001084480.1|rcsb pdb:4G56|interpro:IPR025799|interpro:IPR007857(Skb1 methyltransferase)|interpro:IPR035075|interpro:IPR035248|interpro:IPR035247|interpro:IPR029063|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0034709"(methylosome)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0051301"(cell division)|go:"GO:0070888"(E-box binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)	-	-	-	figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2019/03/06	2019/03/08	rogid:EhupNycgSXZAXxK7wdMWmetWxE48355	rogid:WkUcg9FeSOXhO7okiQs6tPTiHU08355	rigid:UA3MfRYvEitIi6woG4WvQvxxU18	false	his tag:n-n	his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6NUD0	uniprotkb:Q6NUA1	intact:EBI-21229433	intact:EBI-21229405	psi-mi:mep50_xenla(display_long)|uniprotkb:WD repeat-containing protein 77(gene name synonym)|uniprotkb:wdr77(gene name)|psi-mi:wdr77(display_short)|uniprotkb:mep50(gene name synonym)	psi-mi:anm5_xenla(display_long)|uniprotkb:Histone synthetic lethal 7 protein(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT5(gene name synonym)|uniprotkb:prmt5(gene name)|psi-mi:prmt5(display_short)|uniprotkb:hsl7(gene name synonym)	psi-mi:"MI:0104"(static light scattering)	Ho et al. (2012)	pubmed:23451136|imex:IM-27220	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-21237238|imex:IM-27220-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001084703.1|rcsb pdb:4G56|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|go:"GO:0005829"(cytosol)|go:"GO:0034709"(methylosome)|go:"GO:0035097"(histone methyltransferase complex)	refseq:NP_001084480.1|rcsb pdb:4G56|interpro:IPR025799|interpro:IPR007857(Skb1 methyltransferase)|interpro:IPR035075|interpro:IPR035248|interpro:IPR035247|interpro:IPR029063|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0034709"(methylosome)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0051301"(cell division)|go:"GO:0070888"(E-box binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)	-	-	-	figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2019/03/06	2019/03/08	rogid:EhupNycgSXZAXxK7wdMWmetWxE48355	rogid:WkUcg9FeSOXhO7okiQs6tPTiHU08355	rigid:UA3MfRYvEitIi6woG4WvQvxxU18	false	his tag:n-n	his tag:n-n	4	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6NUD0	uniprotkb:Q6NUA1	intact:EBI-21229433	intact:EBI-21229405	psi-mi:mep50_xenla(display_long)|uniprotkb:WD repeat-containing protein 77(gene name synonym)|uniprotkb:wdr77(gene name)|psi-mi:wdr77(display_short)|uniprotkb:mep50(gene name synonym)	psi-mi:anm5_xenla(display_long)|uniprotkb:Histone synthetic lethal 7 protein(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT5(gene name synonym)|uniprotkb:prmt5(gene name)|psi-mi:prmt5(display_short)|uniprotkb:hsl7(gene name synonym)	psi-mi:"MI:0028"(cosedimentation in solution)	Ho et al. (2012)	pubmed:23451136|imex:IM-27220	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-21237253|imex:IM-27220-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001084703.1|rcsb pdb:4G56|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|go:"GO:0005829"(cytosol)|go:"GO:0034709"(methylosome)|go:"GO:0035097"(histone methyltransferase complex)	refseq:NP_001084480.1|rcsb pdb:4G56|interpro:IPR025799|interpro:IPR007857(Skb1 methyltransferase)|interpro:IPR035075|interpro:IPR035248|interpro:IPR035247|interpro:IPR029063|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0034709"(methylosome)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0051301"(cell division)|go:"GO:0070888"(E-box binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)	-	-	-	figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2019/03/06	2019/03/08	rogid:EhupNycgSXZAXxK7wdMWmetWxE48355	rogid:WkUcg9FeSOXhO7okiQs6tPTiHU08355	rigid:UA3MfRYvEitIi6woG4WvQvxxU18	false	his tag:n-n	his tag:n-n	4	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6NUD0	uniprotkb:Q6NUA1	intact:EBI-21229433	intact:EBI-21229405	psi-mi:mep50_xenla(display_long)|uniprotkb:WD repeat-containing protein 77(gene name synonym)|uniprotkb:wdr77(gene name)|psi-mi:wdr77(display_short)|uniprotkb:mep50(gene name synonym)	psi-mi:anm5_xenla(display_long)|uniprotkb:Histone synthetic lethal 7 protein(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT5(gene name synonym)|uniprotkb:prmt5(gene name)|psi-mi:prmt5(display_short)|uniprotkb:hsl7(gene name synonym)	psi-mi:"MI:0826"(x ray scattering)	Ho et al. (2012)	pubmed:23451136|imex:IM-27220	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-21237268|imex:IM-27220-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001084703.1|rcsb pdb:4G56|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|go:"GO:0005829"(cytosol)|go:"GO:0034709"(methylosome)|go:"GO:0035097"(histone methyltransferase complex)	refseq:NP_001084480.1|rcsb pdb:4G56|interpro:IPR025799|interpro:IPR007857(Skb1 methyltransferase)|interpro:IPR035075|interpro:IPR035248|interpro:IPR035247|interpro:IPR029063|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0034709"(methylosome)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0051301"(cell division)|go:"GO:0070888"(E-box binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)	-	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2019/03/06	2019/03/08	rogid:EhupNycgSXZAXxK7wdMWmetWxE48355	rogid:WkUcg9FeSOXhO7okiQs6tPTiHU08355	rigid:UA3MfRYvEitIi6woG4WvQvxxU18	false	his tag:n-n	his tag:n-n	4	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)