#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
chebi:"CHEBI:29108"	uniprotkb:P07357	intact:EBI-1169353	intact:EBI-9021639|uniprotkb:Q9H130|uniprotkb:A2RUI4|uniprotkb:Q13668|uniprotkb:A2RUI5|ensembl:ENSP00000354458	psi-mi:"calcium(2+)"(display_short)|psi-mi:"CHEBI:29108"(display_long)	psi-mi:co8a_human(display_long)|uniprotkb:C8A(gene name)|psi-mi:C8A(display_short)|uniprotkb:Complement component 8 subunit alpha(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Lovelace et al. (2011)	imex:IM-27059|pubmed:21454577	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21446921|wwpdb:3ojy|imex:IM-27059-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_000553.1|dip:DIP-1125N|ensembl:ENSG00000157131(gene)|ensembl:ENST00000361249(transcript)|go:"GO:0001848"(complement binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005579"(membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0006955"(immune response)|go:"GO:0006956"(complement activation)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0016020"(membrane)|go:"GO:0019835"(cytolysis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001862(Membrane attack complex component/perforin/complement C9)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR020863|interpro:IPR020864|interpro:IPR023415|interpro:IPR036055|interpro:IPR036383|interpro:IPR037565|rcsb pdb:2QOS|rcsb pdb:2QQH|rcsb pdb:2RD7|rcsb pdb:3OJY|rcsb pdb:6H03|rcsb pdb:6H04|reactome:R-HSA-166665|reactome:R-HSA-977606	-	-	-	figure legend:Fig. 1, Table1|3d-r-factors:Rwork= 0.249, Rfree=0.337|3d-resolution:2.51A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/06/03	2020/02/18	-	rogid:yxjkH/5pI3e1Sq3z4cycR2D7BqA9606	-	false	-	sufficient binding region:31-584|2'-alpha-mannosyl-L-tryptophan:44-44,542-542,545-545,548-548	2	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:29108"	uniprotkb:P07358	intact:EBI-1169353	intact:EBI-12523855|uniprotkb:A1L4K7|ensembl:ENSP00000360281	psi-mi:"calcium(2+)"(display_short)|psi-mi:"CHEBI:29108"(display_long)	psi-mi:co8b_human(display_long)|uniprotkb:C8B(gene name)|psi-mi:C8B(display_short)|uniprotkb:Complement component 8 subunit beta(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Lovelace et al. (2011)	imex:IM-27059|pubmed:21454577	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21446921|wwpdb:3ojy|imex:IM-27059-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_000057.2|refseq:XP_016857724.1|ensembl:ENSG00000021852(gene)|ensembl:ENST00000371237(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005579"(membrane attack complex)|go:"GO:0006955"(immune response)|go:"GO:0006956"(complement activation)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0016020"(membrane)|go:"GO:0019835"(cytolysis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001862(Membrane attack complex component/perforin/complement C9)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR020863|interpro:IPR020864|interpro:IPR023415|interpro:IPR036055|interpro:IPR036383|interpro:IPR037566|rcsb pdb:3OJY|rcsb pdb:6H03|rcsb pdb:6H04|reactome:R-HSA-166665|reactome:R-HSA-977606	-	-	-	figure legend:Fig. 1, Table1|3d-r-factors:Rwork= 0.249, Rfree=0.337|3d-resolution:2.51A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/06/03	2020/02/18	-	rogid:jevm2nY8n6750D+nkigfM5lmoYI9606	-	false	-	2'-alpha-mannosyl-L-tryptophan:551-551,554-554,70-70,73-73|sufficient binding region:55-591|O-phospho-L-threonine:418-418	2	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:29108"	uniprotkb:P07360	intact:EBI-1169353	intact:EBI-9021652|uniprotkb:Q5SQ07|uniprotkb:Q14CT8|uniprotkb:Q14CU0|ensembl:ENSP00000360697	psi-mi:"calcium(2+)"(display_short)|psi-mi:"CHEBI:29108"(display_long)	psi-mi:co8g_human(display_long)|uniprotkb:C8G(gene name)|psi-mi:C8G(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Lovelace et al. (2011)	imex:IM-27059|pubmed:21454577	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21446921|wwpdb:3ojy|imex:IM-27059-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_000597.2|ensembl:ENSG00000176919(gene)|ensembl:ENST00000371634(transcript)|go:"GO:0001848"(complement binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005579"(membrane attack complex)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0019835"(cytolysis)|go:"GO:0019841"(retinol binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR022272|interpro:IPR043245|rcsb pdb:1IW2|rcsb pdb:1LF7|rcsb pdb:2OVA|rcsb pdb:2OVD|rcsb pdb:2OVE|rcsb pdb:2QOS|rcsb pdb:2RD7|rcsb pdb:3OJY|rcsb pdb:6H03|rcsb pdb:6H04|reactome:R-HSA-166665|reactome:R-HSA-977606|interpro:IPR002968(Alpha-1-microglobulin)	-	-	-	figure legend:Fig. 1, Table1|3d-r-factors:Rwork= 0.249, Rfree=0.337|3d-resolution:2.51A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/06/03	2020/02/18	-	rogid:YU8/KH6FgbBJ00DBO2oEOWZqT0w9606	-	false	-	sufficient binding region:21-202	2	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)