#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0C7Q2 uniprotkb:P02452 intact:EBI-21986906|uniprotkb:B2Y7I5|ensembl:ENSP00000436682 intact:EBI-982999|uniprotkb:O76045|uniprotkb:P78441|uniprotkb:Q13896|uniprotkb:Q13902|uniprotkb:Q13903|uniprotkb:Q14037|uniprotkb:Q14992|uniprotkb:Q15176|uniprotkb:Q15201|uniprotkb:Q16050|uniprotkb:Q59F64|uniprotkb:Q7KZ30|uniprotkb:Q7KZ34|uniprotkb:Q8IVI5|ensembl:ENSP00000225964|uniprotkb:Q8N473|uniprotkb:Q9UML6|uniprotkb:Q9UMM7 psi-mi:arms2_human(display_long)|uniprotkb:ARMS2(gene name)|psi-mi:ARMS2(display_short) psi-mi:co1a1_human(display_long)|uniprotkb:Alpha-1 type I collagen(gene name synonym)|uniprotkb:COL1A1(gene name)|psi-mi:COL1A1(display_short) psi-mi:"MI:0018"(two hybrid) Kortvely et al. (2010) pubmed:19696174|imex:IM-27271 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21988061|imex:IM-27271-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093137.1|ensembl:ENSG00000254636(gene)|ensembl:ENST00000528446(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005739"(mitochondrion) refseq:NP_000079.2|ensembl:ENSG00000108821(gene)|ensembl:ENST00000225964(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001568"(blood vessel development)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001957"(intramembranous ossification)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002020"(protease binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005584"(collagen type I trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0015031"(protein transport)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030141"(secretory granule)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032355"(response to estradiol)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034505"(tooth mineralization)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043588"(skin development)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044691"(tooth eruption)|go:"GO:0046872"(metal ion binding)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0051591"(response to cAMP)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071306"(cellular response to vitamin E)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902618"(cellular response to fluoride)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR008160(Collagen triple helix repeat)|mint:P02452|rcsb pdb:1Q7D|rcsb pdb:2LLP|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:5CTD|rcsb pdb:5CTI|rcsb pdb:5CVA|rcsb pdb:5CVB|rcsb pdb:5K31|rcsb pdb:5OU8|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|rcsb pdb:5OU9|rcsb pdb:7E7B|rcsb pdb:7E7D|reactome:R-HSA-114604|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-198933|reactome:R-HSA-2022090|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-2214320|reactome:R-HSA-2243919|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-8874081|reactome:R-HSA-8940973|reactome:R-HSA-8948216|dip:DIP-36077N - - - figure legend:Table 1 -1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/08/05 2019/08/19 rogid:tj0M2XbmtwRk507SPLfcjOWRJrY9606 rogid:x83+B64Cl9zkAVeZ9RCo0BukkwU9606 rigid:328T+ST7Md/IpwbyC2Av/1vLtVY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C7Q2 uniprotkb:P08572 intact:EBI-21986906|uniprotkb:B2Y7I5|ensembl:ENSP00000436682 intact:EBI-2432506|uniprotkb:Q14052|uniprotkb:Q548C3|uniprotkb:Q5VZA9|uniprotkb:Q66K23|ensembl:ENSP00000353654 psi-mi:arms2_human(display_long)|uniprotkb:ARMS2(gene name)|psi-mi:ARMS2(display_short) psi-mi:co4a2_human(display_long)|uniprotkb:COL4A2(gene name)|psi-mi:COL4A2(display_short) psi-mi:"MI:0018"(two hybrid) Kortvely et al. (2010) pubmed:19696174|imex:IM-27271 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21988065|imex:IM-27271-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093137.1|ensembl:ENSG00000254636(gene)|ensembl:ENST00000528446(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005739"(mitochondrion) refseq:NP_001837.2|ensembl:ENSG00000134871(gene)|ensembl:ENST00000360467(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005587"(collagen type IV trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0007568"(aging)|go:"GO:0014823"(response to activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|interpro:IPR001442(Type 4 procollagen, C-terminal repeat)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016187(C-type lectin fold)|interpro:IPR036954|rcsb pdb:1LI1|rcsb pdb:5NAX|rcsb pdb:5NB2|rcsb pdb:6MPX|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-2214320|reactome:R-HSA-2243919|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-419037|reactome:R-HSA-8948216 - - - figure legend:Table 1 -2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/08/05 2019/08/19 rogid:tj0M2XbmtwRk507SPLfcjOWRJrY9606 rogid:2jSdn1hb9JtAPdSLo82KAbqdzr09606 rigid:pgYAfYoqhS82nJxXhgdIIfc6jYI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C7Q2 uniprotkb:Q9BXX0 intact:EBI-21986906|uniprotkb:B2Y7I5|ensembl:ENSP00000436682 intact:EBI-11740176|uniprotkb:B2RMY3|uniprotkb:Q8NBH3|uniprotkb:Q96JQ4|ensembl:ENSP00000254528 psi-mi:arms2_human(display_long)|uniprotkb:ARMS2(gene name)|psi-mi:ARMS2(display_short) psi-mi:emil2_human(display_long)|uniprotkb:EMILIN2(gene name)|psi-mi:EMILIN2(display_short)|uniprotkb:Elastin microfibril interface-located protein 2(gene name synonym)|uniprotkb:Protein FOAP-10(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kortvely et al. (2010) pubmed:19696174|imex:IM-27271 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21988069|imex:IM-27271-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093137.1|ensembl:ENSG00000254636(gene)|ensembl:ENST00000528446(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005739"(mitochondrion) refseq:NP_114437.2|ensembl:ENSG00000132205(gene)|ensembl:ENST00000254528(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0007155"(cell adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR011489(EMI)|reactome:R-HSA-2129379|go:"GO:0030023"(extracellular matrix constituent conferring elasticity) - - - figure legend:Table 1 -3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/08/05 2019/08/19 rogid:tj0M2XbmtwRk507SPLfcjOWRJrY9606 rogid:YncpkDHFOyL1VjUqbv8fJS1EUAo9606 rigid:WJIIGQpEUyB0ST5of1/XUoRANVo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C7Q2 uniprotkb:P02751 intact:EBI-21986906|uniprotkb:B2Y7I5|ensembl:ENSP00000436682 intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839 psi-mi:arms2_human(display_long)|uniprotkb:ARMS2(gene name)|psi-mi:ARMS2(display_short) psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kortvely et al. (2010) pubmed:19696174|imex:IM-27271 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21988073|imex:IM-27271-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093137.1|ensembl:ENSG00000254636(gene)|ensembl:ENST00000528446(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005739"(mitochondrion) refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223 - - - figure legend:Table 1 -4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/08/05 2019/10/18 rogid:tj0M2XbmtwRk507SPLfcjOWRJrY9606 rogid:4arZu49X8b+dthqaX4DIh59V8h09606 rigid:Bn6wX/KAtgNKCEuIs3lMZjKCHbw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C7Q2 uniprotkb:Q96RW7 intact:EBI-21986906|uniprotkb:B2Y7I5|ensembl:ENSP00000436682 intact:EBI-2806183|ensembl:ENSP00000271588|uniprotkb:Q96DN8|uniprotkb:Q5TYR7|uniprotkb:Q96DN3|uniprotkb:Q96SC3|uniprotkb:A6NGE3 psi-mi:arms2_human(display_long)|uniprotkb:ARMS2(gene name)|psi-mi:ARMS2(display_short) psi-mi:hmcn1_human(display_long)|uniprotkb:FIBL6(gene name synonym)|uniprotkb:Fibulin-6(gene name synonym)|uniprotkb:HMCN1(gene name)|psi-mi:HMCN1(display_short) psi-mi:"MI:0018"(two hybrid) Kortvely et al. (2010) pubmed:19696174|imex:IM-27271 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21988081|imex:IM-27271-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093137.1|ensembl:ENSG00000254636(gene)|ensembl:ENST00000528446(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005739"(mitochondrion) ensembl:ENSG00000143341(gene)|ensembl:ENST00000271588(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|refseq:XP_011508340.1|refseq:NP_114141.2|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007601"(visual perception)|go:"GO:0009617"(response to bacterium)|go:"GO:0032154"(cleavage furrow)|go:"GO:0051301"(cell division)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018097|interpro:IPR026823|interpro:IPR036179|interpro:IPR036383|interpro:IPR036465|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR006605(G2 nidogen and fibulin G2F)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR009017(Green fluorescent protein-like) - - - figure legend:Table 1 -6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/08/05 2019/08/19 rogid:tj0M2XbmtwRk507SPLfcjOWRJrY9606 rogid:hybxCgCN8p6aJ6LoTgeKIfTQzYA9606 rigid:fTbKyvGwLOg6FXAW9BvFuvw97Lo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C7Q2 uniprotkb:Q00887 intact:EBI-21986906|uniprotkb:B2Y7I5|ensembl:ENSP00000436682 intact:EBI-713966|uniprotkb:Q15236|uniprotkb:Q15237|uniprotkb:Q8WW78|uniprotkb:Q9UQ73|ensembl:ENSP00000270077|uniprotkb:B2R869|intact:EBI-7223205|intact:MINT-1195229|uniprotkb:Q15227 psi-mi:arms2_human(display_long)|uniprotkb:ARMS2(gene name)|psi-mi:ARMS2(display_short) psi-mi:psg9_human(display_long)|uniprotkb:Pregnancy-specific beta-1 glycoprotein B(gene name synonym)|uniprotkb:PS34(gene name synonym)|uniprotkb:Pregnancy-specific glycoprotein 7(gene name synonym)|uniprotkb:PSG9(gene name)|psi-mi:PSG9(display_short)|uniprotkb:PSG11(gene name synonym)|uniprotkb:Pregnancy-specific beta-1-glycoprotein 11(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kortvely et al. (2010) pubmed:19696174|imex:IM-27271 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21988085|imex:IM-27271-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093137.1|ensembl:ENSG00000254636(gene)|ensembl:ENST00000528446(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005739"(mitochondrion) ensembl:ENSG00000183668(gene)|ensembl:ENST00000270077(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007565"(female pregnancy)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-202733|refseq:NP_002775.3|refseq:XP_005259132.1|refseq:NP_001288636.1|refseq:NP_001288637.1|refseq:NP_001288638.1 - - - figure legend:Table 1 -7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/08/05 2019/08/19 rogid:tj0M2XbmtwRk507SPLfcjOWRJrY9606 rogid:mjkGpIRSGy54J0ATS6Jp8t6/r1w9606 rigid:LUtNx5xnD6yC5eJwIGguJj2G5nI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P23142-1 uniprotkb:P0C7Q2 intact:EBI-8516738|intact:MINT-245737|ensembl:ENSP00000331544 intact:EBI-21986906|uniprotkb:B2Y7I5|ensembl:ENSP00000436682 psi-mi:p23142-1(display_long)|uniprotkb:FBLN1(gene name)|psi-mi:FBLN1(display_short)|uniprotkb:PP213(orf name) psi-mi:arms2_human(display_long)|uniprotkb:ARMS2(gene name)|psi-mi:ARMS2(display_short) psi-mi:"MI:0018"(two hybrid) Kortvely et al. (2010) pubmed:19696174|imex:IM-27271 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21988113|imex:IM-27271-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-726652(isoform-parent)|ensembl:ENSG00000077942(gene)|ensembl:ENST00000327858(transcript) refseq:NP_001093137.1|ensembl:ENSG00000254636(gene)|ensembl:ENST00000528446(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005739"(mitochondrion) - comment:mint - figure legend:Table 1 -5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/08/05 2019/09/02 rogid:a47ZJLXWeghGIY9xJTQI7VujuMk9606 rogid:tj0M2XbmtwRk507SPLfcjOWRJrY9606 rigid:iLxtywNvpxzYas+Of3oz2Lvgt9E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N6F8 uniprotkb:P0C7Q2 intact:EBI-8487781|intact:MINT-8417729|ensembl:ENSP00000297873 intact:EBI-21986906|uniprotkb:B2Y7I5|ensembl:ENSP00000436682 psi-mi:met27_human(display_long)|uniprotkb:METTL27(gene name)|psi-mi:METTL27(display_short)|uniprotkb:WBSCR27(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 27 protein(gene name synonym) psi-mi:arms2_human(display_long)|uniprotkb:ARMS2(gene name)|psi-mi:ARMS2(display_short) psi-mi:"MI:0018"(two hybrid) Kortvely et al. (2010) pubmed:19696174|imex:IM-27271 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21988125|imex:IM-27271-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689772.2|ensembl:ENSG00000165171(gene)|ensembl:ENST00000297873(transcript)|go:"GO:0008168"(methyltransferase activity)|interpro:IPR029063|interpro:IPR041698|mint:Q8N6F8 refseq:NP_001093137.1|ensembl:ENSG00000254636(gene)|ensembl:ENST00000528446(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005739"(mitochondrion) - comment:mint|comment:homomint - figure legend:Table 1 -9|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/08/05 2019/08/19 rogid:T+4JBqFxUvWNzHLf1bT6SGLCaJs9606 rogid:tj0M2XbmtwRk507SPLfcjOWRJrY9606 rigid:rR/9FaNoiYGTt4SX3HWiOgtJzgU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C7Q2 uniprotkb:Q9UQ72 intact:EBI-21986906|uniprotkb:B2Y7I5|ensembl:ENSP00000436682 intact:EBI-21974170|uniprotkb:Q13179|uniprotkb:Q15242|uniprotkb:Q8WW91|uniprotkb:Q9UNE4|ensembl:ENSP00000319140 psi-mi:arms2_human(display_long)|uniprotkb:ARMS2(gene name)|psi-mi:ARMS2(display_short) psi-mi:psg11_human(display_long)|uniprotkb:PSG11(gene name)|psi-mi:PSG11(display_short)|uniprotkb:PSG13(gene name synonym)|uniprotkb:PSG14(gene name synonym)|uniprotkb:Pregnancy-specific beta-1-glycoprotein 13(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kortvely et al. (2010) pubmed:19696174|imex:IM-27271 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21988129|imex:IM-27271-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093137.1|ensembl:ENSG00000254636(gene)|ensembl:ENST00000528446(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005739"(mitochondrion) refseq:NP_001106881.1|refseq:NP_002776.3|refseq:NP_976032.2|ensembl:ENSG00000243130(gene)|ensembl:ENST00000320078(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007565"(female pregnancy)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-202733 - - - figure legend:Table 1 -8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/08/05 2019/08/19 rogid:tj0M2XbmtwRk507SPLfcjOWRJrY9606 rogid:5jzOv/gBiVrbHqNJnkBZSGxxcs89606 rigid:daG1gKPl7pVyf5QtTp6PCb4c39I false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C7Q2 uniprotkb:P23142 intact:EBI-21986906|uniprotkb:B2Y7I5|ensembl:ENSP00000436682 intact:EBI-726652|uniprotkb:P23143|uniprotkb:P23144|uniprotkb:P37888|uniprotkb:Q5TIC4|uniprotkb:Q8TBH8|uniprotkb:Q9HBQ5|uniprotkb:Q9UC21|uniprotkb:Q9UGR4|uniprotkb:Q9UH41|uniprotkb:B0QY42|intact:EBI-2562209|ensembl:ENSP00000331544|uniprotkb:B1AHL4 psi-mi:arms2_human(display_long)|uniprotkb:ARMS2(gene name)|psi-mi:ARMS2(display_short) psi-mi:fbln1_human(display_long)|uniprotkb:FBLN1(gene name)|psi-mi:FBLN1(display_short)|uniprotkb:PP213(orf name) psi-mi:"MI:0018"(two hybrid) Kortvely et al. (2010) pubmed:19696174|imex:IM-27271 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21988077|imex:IM-27271-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093137.1|ensembl:ENSG00000254636(gene)|ensembl:ENST00000528446(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005739"(mitochondrion) refseq:NP_001987.2|refseq:NP_006476.2|refseq:NP_006477.2|refseq:NP_006478.2|ensembl:ENSG00000077942(gene)|ensembl:ENST00000327858(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007566"(embryo implantation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070051"(fibrinogen binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0071953"(elastic fiber)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904188"(negative regulation of transformation of host cell by virus)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000647"(negative regulation of stem cell proliferation)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR017048(Fibulin-1)|interpro:IPR018097|interpro:IPR026823|mint:P23142|reactome:R-HSA-2129379|go:"GO:0005201"(extracellular matrix structural constituent) - - - figure legend:Supplementary Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/08/05 2019/08/19 rogid:tj0M2XbmtwRk507SPLfcjOWRJrY9606 rogid:a47ZJLXWeghGIY9xJTQI7VujuMk9606 rigid:iLxtywNvpxzYas+Of3oz2Lvgt9E false mutation with no effect:69-69(rs10490924) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C7Q2 uniprotkb:Q9UQ72 intact:EBI-21986906|uniprotkb:B2Y7I5|ensembl:ENSP00000436682 intact:EBI-21974170|uniprotkb:Q13179|uniprotkb:Q15242|uniprotkb:Q8WW91|uniprotkb:Q9UNE4|ensembl:ENSP00000319140 psi-mi:arms2_human(display_long)|uniprotkb:ARMS2(gene name)|psi-mi:ARMS2(display_short) psi-mi:psg11_human(display_long)|uniprotkb:PSG11(gene name)|psi-mi:PSG11(display_short)|uniprotkb:PSG13(gene name synonym)|uniprotkb:PSG14(gene name synonym)|uniprotkb:Pregnancy-specific beta-1-glycoprotein 13(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kortvely et al. (2010) pubmed:19696174|imex:IM-27271 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21988093|imex:IM-27271-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093137.1|ensembl:ENSG00000254636(gene)|ensembl:ENST00000528446(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005739"(mitochondrion) refseq:NP_001106881.1|refseq:NP_002776.3|refseq:NP_976032.2|ensembl:ENSG00000243130(gene)|ensembl:ENST00000320078(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007565"(female pregnancy)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-202733 - - - figure legend:Supplementary Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/08/05 2019/08/19 rogid:tj0M2XbmtwRk507SPLfcjOWRJrY9606 rogid:5jzOv/gBiVrbHqNJnkBZSGxxcs89606 rigid:daG1gKPl7pVyf5QtTp6PCb4c39I false mutation with no effect:69-69(rs10490924) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C7Q2 uniprotkb:P02452 intact:EBI-21986906|uniprotkb:B2Y7I5|ensembl:ENSP00000436682 intact:EBI-982999|uniprotkb:O76045|uniprotkb:P78441|uniprotkb:Q13896|uniprotkb:Q13902|uniprotkb:Q13903|uniprotkb:Q14037|uniprotkb:Q14992|uniprotkb:Q15176|uniprotkb:Q15201|uniprotkb:Q16050|uniprotkb:Q59F64|uniprotkb:Q7KZ30|uniprotkb:Q7KZ34|uniprotkb:Q8IVI5|ensembl:ENSP00000225964|uniprotkb:Q8N473|uniprotkb:Q9UML6|uniprotkb:Q9UMM7 psi-mi:arms2_human(display_long)|uniprotkb:ARMS2(gene name)|psi-mi:ARMS2(display_short) psi-mi:co1a1_human(display_long)|uniprotkb:Alpha-1 type I collagen(gene name synonym)|uniprotkb:COL1A1(gene name)|psi-mi:COL1A1(display_short) psi-mi:"MI:0018"(two hybrid) Kortvely et al. (2010) pubmed:19696174|imex:IM-27271 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21988097|imex:IM-27271-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093137.1|ensembl:ENSG00000254636(gene)|ensembl:ENST00000528446(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005739"(mitochondrion) refseq:NP_000079.2|ensembl:ENSG00000108821(gene)|ensembl:ENST00000225964(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001568"(blood vessel development)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001957"(intramembranous ossification)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002020"(protease binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005584"(collagen type I trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0015031"(protein transport)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030141"(secretory granule)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032355"(response to estradiol)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034505"(tooth mineralization)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043588"(skin development)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044691"(tooth eruption)|go:"GO:0046872"(metal ion binding)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0051591"(response to cAMP)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071306"(cellular response to vitamin E)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902618"(cellular response to fluoride)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR008160(Collagen triple helix repeat)|mint:P02452|rcsb pdb:1Q7D|rcsb pdb:2LLP|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:5CTD|rcsb pdb:5CTI|rcsb pdb:5CVA|rcsb pdb:5CVB|rcsb pdb:5K31|rcsb pdb:5OU8|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|rcsb pdb:5OU9|rcsb pdb:7E7B|rcsb pdb:7E7D|reactome:R-HSA-114604|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-198933|reactome:R-HSA-2022090|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-2214320|reactome:R-HSA-2243919|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-8874081|reactome:R-HSA-8940973|reactome:R-HSA-8948216|dip:DIP-36077N - - - figure legend:Supplementary Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/08/05 2019/08/19 rogid:tj0M2XbmtwRk507SPLfcjOWRJrY9606 rogid:x83+B64Cl9zkAVeZ9RCo0BukkwU9606 rigid:328T+ST7Md/IpwbyC2Av/1vLtVY false mutation with no effect:69-69(rs10490924) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C7Q2 uniprotkb:Q00887 intact:EBI-21986906|uniprotkb:B2Y7I5|ensembl:ENSP00000436682 intact:EBI-713966|uniprotkb:Q15236|uniprotkb:Q15237|uniprotkb:Q8WW78|uniprotkb:Q9UQ73|ensembl:ENSP00000270077|uniprotkb:B2R869|intact:EBI-7223205|intact:MINT-1195229|uniprotkb:Q15227 psi-mi:arms2_human(display_long)|uniprotkb:ARMS2(gene name)|psi-mi:ARMS2(display_short) psi-mi:psg9_human(display_long)|uniprotkb:Pregnancy-specific beta-1 glycoprotein B(gene name synonym)|uniprotkb:PS34(gene name synonym)|uniprotkb:Pregnancy-specific glycoprotein 7(gene name synonym)|uniprotkb:PSG9(gene name)|psi-mi:PSG9(display_short)|uniprotkb:PSG11(gene name synonym)|uniprotkb:Pregnancy-specific beta-1-glycoprotein 11(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kortvely et al. (2010) pubmed:19696174|imex:IM-27271 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21988121|imex:IM-27271-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093137.1|ensembl:ENSG00000254636(gene)|ensembl:ENST00000528446(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005739"(mitochondrion) ensembl:ENSG00000183668(gene)|ensembl:ENST00000270077(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007565"(female pregnancy)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-202733|refseq:NP_002775.3|refseq:XP_005259132.1|refseq:NP_001288636.1|refseq:NP_001288637.1|refseq:NP_001288638.1 - - - figure legend:Supplementary Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/08/05 2019/08/19 rogid:tj0M2XbmtwRk507SPLfcjOWRJrY9606 rogid:mjkGpIRSGy54J0ATS6Jp8t6/r1w9606 rigid:LUtNx5xnD6yC5eJwIGguJj2G5nI false mutation with no effect:69-69(rs10490924) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C7Q2 uniprotkb:Q96RW7 intact:EBI-21986906|uniprotkb:B2Y7I5|ensembl:ENSP00000436682 intact:EBI-2806183|ensembl:ENSP00000271588|uniprotkb:Q96DN8|uniprotkb:Q5TYR7|uniprotkb:Q96DN3|uniprotkb:Q96SC3|uniprotkb:A6NGE3 psi-mi:arms2_human(display_long)|uniprotkb:ARMS2(gene name)|psi-mi:ARMS2(display_short) psi-mi:hmcn1_human(display_long)|uniprotkb:FIBL6(gene name synonym)|uniprotkb:Fibulin-6(gene name synonym)|uniprotkb:HMCN1(gene name)|psi-mi:HMCN1(display_short) psi-mi:"MI:0018"(two hybrid) Kortvely et al. (2010) pubmed:19696174|imex:IM-27271 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21988117|imex:IM-27271-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093137.1|ensembl:ENSG00000254636(gene)|ensembl:ENST00000528446(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005739"(mitochondrion) ensembl:ENSG00000143341(gene)|ensembl:ENST00000271588(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|refseq:XP_011508340.1|refseq:NP_114141.2|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007601"(visual perception)|go:"GO:0009617"(response to bacterium)|go:"GO:0032154"(cleavage furrow)|go:"GO:0051301"(cell division)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018097|interpro:IPR026823|interpro:IPR036179|interpro:IPR036383|interpro:IPR036465|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR006605(G2 nidogen and fibulin G2F)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR009017(Green fluorescent protein-like) - - - figure legend:Supplementary Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/08/05 2019/08/19 rogid:tj0M2XbmtwRk507SPLfcjOWRJrY9606 rogid:hybxCgCN8p6aJ6LoTgeKIfTQzYA9606 rigid:fTbKyvGwLOg6FXAW9BvFuvw97Lo false mutation with no effect:69-69(rs10490924) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C7Q2 uniprotkb:Q9BXX0 intact:EBI-21986906|uniprotkb:B2Y7I5|ensembl:ENSP00000436682 intact:EBI-11740176|uniprotkb:B2RMY3|uniprotkb:Q8NBH3|uniprotkb:Q96JQ4|ensembl:ENSP00000254528 psi-mi:arms2_human(display_long)|uniprotkb:ARMS2(gene name)|psi-mi:ARMS2(display_short) psi-mi:emil2_human(display_long)|uniprotkb:EMILIN2(gene name)|psi-mi:EMILIN2(display_short)|uniprotkb:Elastin microfibril interface-located protein 2(gene name synonym)|uniprotkb:Protein FOAP-10(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kortvely et al. (2010) pubmed:19696174|imex:IM-27271 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21988109|imex:IM-27271-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093137.1|ensembl:ENSG00000254636(gene)|ensembl:ENST00000528446(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005739"(mitochondrion) refseq:NP_114437.2|ensembl:ENSG00000132205(gene)|ensembl:ENST00000254528(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0007155"(cell adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR011489(EMI)|reactome:R-HSA-2129379|go:"GO:0030023"(extracellular matrix constituent conferring elasticity) - - - figure legend:Supplementary Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/08/05 2019/08/19 rogid:tj0M2XbmtwRk507SPLfcjOWRJrY9606 rogid:YncpkDHFOyL1VjUqbv8fJS1EUAo9606 rigid:WJIIGQpEUyB0ST5of1/XUoRANVo false mutation with no effect:69-69(rs10490924) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C7Q2 uniprotkb:P08572 intact:EBI-21986906|uniprotkb:B2Y7I5|ensembl:ENSP00000436682 intact:EBI-2432506|uniprotkb:Q14052|uniprotkb:Q548C3|uniprotkb:Q5VZA9|uniprotkb:Q66K23|ensembl:ENSP00000353654 psi-mi:arms2_human(display_long)|uniprotkb:ARMS2(gene name)|psi-mi:ARMS2(display_short) psi-mi:co4a2_human(display_long)|uniprotkb:COL4A2(gene name)|psi-mi:COL4A2(display_short) psi-mi:"MI:0018"(two hybrid) Kortvely et al. (2010) pubmed:19696174|imex:IM-27271 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21988105|imex:IM-27271-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093137.1|ensembl:ENSG00000254636(gene)|ensembl:ENST00000528446(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005739"(mitochondrion) refseq:NP_001837.2|ensembl:ENSG00000134871(gene)|ensembl:ENST00000360467(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005587"(collagen type IV trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0007568"(aging)|go:"GO:0014823"(response to activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|interpro:IPR001442(Type 4 procollagen, C-terminal repeat)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016187(C-type lectin fold)|interpro:IPR036954|rcsb pdb:1LI1|rcsb pdb:5NAX|rcsb pdb:5NB2|rcsb pdb:6MPX|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-2214320|reactome:R-HSA-2243919|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-419037|reactome:R-HSA-8948216 - - - figure legend:Supplementary Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/08/05 2019/08/19 rogid:tj0M2XbmtwRk507SPLfcjOWRJrY9606 rogid:2jSdn1hb9JtAPdSLo82KAbqdzr09606 rigid:pgYAfYoqhS82nJxXhgdIIfc6jYI false mutation with no effect:69-69(rs10490924) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C7Q2 uniprotkb:P02751 intact:EBI-21986906|uniprotkb:B2Y7I5|ensembl:ENSP00000436682 intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839 psi-mi:arms2_human(display_long)|uniprotkb:ARMS2(gene name)|psi-mi:ARMS2(display_short) psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kortvely et al. (2010) pubmed:19696174|imex:IM-27271 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21988101|imex:IM-27271-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093137.1|ensembl:ENSG00000254636(gene)|ensembl:ENST00000528446(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005739"(mitochondrion) refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223 - - - figure legend:Supplementary Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/08/05 2019/10/18 rogid:tj0M2XbmtwRk507SPLfcjOWRJrY9606 rogid:4arZu49X8b+dthqaX4DIh59V8h09606 rigid:Bn6wX/KAtgNKCEuIs3lMZjKCHbw false mutation with no effect:69-69(rs10490924) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96RW7 uniprotkb:P0C7Q2 intact:EBI-2806183|ensembl:ENSP00000271588|uniprotkb:Q96DN8|uniprotkb:Q5TYR7|uniprotkb:Q96DN3|uniprotkb:Q96SC3|uniprotkb:A6NGE3 intact:EBI-21986906|uniprotkb:B2Y7I5|ensembl:ENSP00000436682 psi-mi:hmcn1_human(display_long)|uniprotkb:FIBL6(gene name synonym)|uniprotkb:Fibulin-6(gene name synonym)|uniprotkb:HMCN1(gene name)|psi-mi:HMCN1(display_short) psi-mi:arms2_human(display_long)|uniprotkb:ARMS2(gene name)|psi-mi:ARMS2(display_short) psi-mi:"MI:0096"(pull down) Kortvely et al. (2010) pubmed:19696174|imex:IM-27271 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21988202|imex:IM-27271-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143341(gene)|ensembl:ENST00000271588(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|refseq:XP_011508340.1|refseq:NP_114141.2|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007601"(visual perception)|go:"GO:0009617"(response to bacterium)|go:"GO:0032154"(cleavage furrow)|go:"GO:0051301"(cell division)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018097|interpro:IPR026823|interpro:IPR036179|interpro:IPR036383|interpro:IPR036465|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR006605(G2 nidogen and fibulin G2F)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR009017(Green fluorescent protein-like) refseq:NP_001093137.1|ensembl:ENSG00000254636(gene)|ensembl:ENST00000528446(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005739"(mitochondrion) - - - figure legend:6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/08/05 2019/08/19 rogid:hybxCgCN8p6aJ6LoTgeKIfTQzYA9606 rogid:tj0M2XbmtwRk507SPLfcjOWRJrY9606 rigid:fTbKyvGwLOg6FXAW9BvFuvw97Lo false ha tag:?-? flag tag:n-n|strep ii tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96RW7 uniprotkb:P0C7Q2 intact:EBI-2806183|ensembl:ENSP00000271588|uniprotkb:Q96DN8|uniprotkb:Q5TYR7|uniprotkb:Q96DN3|uniprotkb:Q96SC3|uniprotkb:A6NGE3 intact:EBI-21986906|uniprotkb:B2Y7I5|ensembl:ENSP00000436682 psi-mi:hmcn1_human(display_long)|uniprotkb:FIBL6(gene name synonym)|uniprotkb:Fibulin-6(gene name synonym)|uniprotkb:HMCN1(gene name)|psi-mi:HMCN1(display_short) psi-mi:arms2_human(display_long)|uniprotkb:ARMS2(gene name)|psi-mi:ARMS2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kortvely et al. (2010) pubmed:19696174|imex:IM-27271 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21988218|imex:IM-27271-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143341(gene)|ensembl:ENST00000271588(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|refseq:XP_011508340.1|refseq:NP_114141.2|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007601"(visual perception)|go:"GO:0009617"(response to bacterium)|go:"GO:0032154"(cleavage furrow)|go:"GO:0051301"(cell division)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018097|interpro:IPR026823|interpro:IPR036179|interpro:IPR036383|interpro:IPR036465|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR006605(G2 nidogen and fibulin G2F)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR009017(Green fluorescent protein-like) refseq:NP_001093137.1|ensembl:ENSG00000254636(gene)|ensembl:ENST00000528446(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005739"(mitochondrion) - - - figure legend:6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/08/05 2019/08/19 rogid:hybxCgCN8p6aJ6LoTgeKIfTQzYA9606 rogid:tj0M2XbmtwRk507SPLfcjOWRJrY9606 rigid:fTbKyvGwLOg6FXAW9BvFuvw97Lo false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)