#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P21549 uniprotkb:P21549 intact:EBI-727098|uniprotkb:Q53QU6|ensembl:ENSP00000302620 intact:EBI-727098|uniprotkb:Q53QU6|ensembl:ENSP00000302620 psi-mi:spya_human(display_long)|uniprotkb:Alanine--glyoxylate aminotransferase(gene name synonym)|uniprotkb:AGXT(gene name)|psi-mi:AGXT(display_short)|uniprotkb:AGT1(gene name synonym)|uniprotkb:SPAT(gene name synonym) psi-mi:spya_human(display_long)|uniprotkb:Alanine--glyoxylate aminotransferase(gene name synonym)|uniprotkb:AGXT(gene name)|psi-mi:AGXT(display_short)|uniprotkb:AGT1(gene name synonym)|uniprotkb:SPAT(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Zhang et al. (2003) pubmed:12899834|imex:IM-27250 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-21224438|wwpdb:1H0C|imex:IM-27250-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000021.1|ensembl:ENSG00000172482(gene)|ensembl:ENST00000307503(transcript)|go:"GO:0004760"(serine-pyruvate transaminase activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0008453"(alanine-glyoxylate transaminase activity)|go:"GO:0008483"(transaminase activity)|go:"GO:0009436"(glyoxylate catabolic process)|go:"GO:0016597"(amino acid binding)|go:"GO:0019265"(glycine biosynthetic process, by transamination of glyoxylate)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042853"(L-alanine catabolic process)|go:"GO:0042866"(pyruvate biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0046487"(glyoxylate metabolic process)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR020578|interpro:IPR024169|rcsb pdb:1H0C|rcsb pdb:1J04|rcsb pdb:2YOB|rcsb pdb:3R9A|rcsb pdb:4CBR|rcsb pdb:4CBS|rcsb pdb:4I8A|rcsb pdb:4KXK|rcsb pdb:4KYO|rcsb pdb:5F9S|rcsb pdb:5HHY|rcsb pdb:5LUC|rcsb pdb:5OFY|rcsb pdb:5OG0|rcsb pdb:6RV0|rcsb pdb:6RV1|reactome:R-HSA-389661|reactome:R-HSA-9033241|dip:DIP-59650N refseq:NP_000021.1|ensembl:ENSG00000172482(gene)|ensembl:ENST00000307503(transcript)|go:"GO:0004760"(serine-pyruvate transaminase activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0008453"(alanine-glyoxylate transaminase activity)|go:"GO:0008483"(transaminase activity)|go:"GO:0009436"(glyoxylate catabolic process)|go:"GO:0016597"(amino acid binding)|go:"GO:0019265"(glycine biosynthetic process, by transamination of glyoxylate)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042853"(L-alanine catabolic process)|go:"GO:0042866"(pyruvate biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0046487"(glyoxylate metabolic process)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR020578|interpro:IPR024169|rcsb pdb:1H0C|rcsb pdb:1J04|rcsb pdb:2YOB|rcsb pdb:3R9A|rcsb pdb:4CBR|rcsb pdb:4CBS|rcsb pdb:4I8A|rcsb pdb:4KXK|rcsb pdb:4KYO|rcsb pdb:5F9S|rcsb pdb:5HHY|rcsb pdb:5LUC|rcsb pdb:5OFY|rcsb pdb:5OG0|rcsb pdb:6RV0|rcsb pdb:6RV1|reactome:R-HSA-389661|reactome:R-HSA-9033241|dip:DIP-59650N - - - figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2019/02/26 2019/02/27 rogid:9rs7LV3MQKPIr6O8g+rweIW6NIo9606 rogid:9rs7LV3MQKPIr6O8g+rweIW6NIo9606 rigid:EKQ9UKjTpOKXO/FwQGJbCwQFwVI false his tag:c-c his tag:c-c 2 0 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)