#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P00784	uniprotkb:P01040	intact:EBI-8501709|intact:MINT-1504623	intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90	psi-mi:papa1_carpa(display_long)|uniprotkb:Papaya proteinase I(gene name synonym)	psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym)	psi-mi:"MI:0051"(fluorescence technology)	Estrada et al. (2000)	pubmed:11152132|imex:IM-27123	taxid:3649(papaya)|taxid:3649(Carica papaya)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-21293302|imex:IM-27123-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4QRG|rcsb pdb:4QRV|rcsb pdb:4QRX|rcsb pdb:6H8T|rcsb pdb:3USV|rcsb pdb:5PAD|rcsb pdb:1PAD|rcsb pdb:1PE6|rcsb pdb:1PPD|interpro:IPR025660|rcsb pdb:9PAP|rcsb pdb:1POP|interpro:IPR025661|rcsb pdb:3E1Z|rcsb pdb:1KHP|rcsb pdb:1BQI|rcsb pdb:1STF|rcsb pdb:3LFY|rcsb pdb:6PAD|rcsb pdb:3TNX|rcsb pdb:4PAD|rcsb pdb:2CIO|rcsb pdb:1KHQ|rcsb pdb:1BP4|rcsb pdb:1PPP|rcsb pdb:1PPN|rcsb pdb:1CVZ|rcsb pdb:1EFF|rcsb pdb:3IMA|rcsb pdb:2PAD|rcsb pdb:1PIP|rcsb pdb:6TCX|interpro:IPR039417|interpro:IPR038765|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0097655"(serpin family protein binding)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR013201(Proteinase inhibitor I29, cathepsin propeptide)	refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis)	-	comment:mint	-	figure legend:Fig. 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/02	2019/04/02	rogid:00kdpPgtZLbD9N1urTAgF53aqYo3649	rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606	rigid:iFgQ2F/adJAQ2fKbpCZhZS/zj0g	false	-	fluorescent dye label:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0867"(tag visualisation by fluorescence)|psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P00784	uniprotkb:P01040	intact:EBI-8501709|intact:MINT-1504623	intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90	psi-mi:papa1_carpa(display_long)|uniprotkb:Papaya proteinase I(gene name synonym)	psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym)	psi-mi:"MI:0051"(fluorescence technology)	Estrada et al. (2000)	pubmed:11152132|imex:IM-27123	taxid:3649(papaya)|taxid:3649(Carica papaya)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-21293308|imex:IM-27123-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4QRG|rcsb pdb:4QRV|rcsb pdb:4QRX|rcsb pdb:6H8T|rcsb pdb:3USV|rcsb pdb:5PAD|rcsb pdb:1PAD|rcsb pdb:1PE6|rcsb pdb:1PPD|interpro:IPR025660|rcsb pdb:9PAP|rcsb pdb:1POP|interpro:IPR025661|rcsb pdb:3E1Z|rcsb pdb:1KHP|rcsb pdb:1BQI|rcsb pdb:1STF|rcsb pdb:3LFY|rcsb pdb:6PAD|rcsb pdb:3TNX|rcsb pdb:4PAD|rcsb pdb:2CIO|rcsb pdb:1KHQ|rcsb pdb:1BP4|rcsb pdb:1PPP|rcsb pdb:1PPN|rcsb pdb:1CVZ|rcsb pdb:1EFF|rcsb pdb:3IMA|rcsb pdb:2PAD|rcsb pdb:1PIP|rcsb pdb:6TCX|interpro:IPR039417|interpro:IPR038765|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0097655"(serpin family protein binding)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR013201(Proteinase inhibitor I29, cathepsin propeptide)	refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis)	-	comment:mint	-	figure legend:Fig. 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/02	2019/04/02	rogid:00kdpPgtZLbD9N1urTAgF53aqYo3649	rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606	rigid:iFgQ2F/adJAQ2fKbpCZhZS/zj0g	false	-	fluorescent dye label:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0867"(tag visualisation by fluorescence)|psi-mi:"MI:0396"(predetermined participant)