#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P28300-PRO_0000018520	uniprotkb:P12109	intact:EBI-20724846	intact:EBI-2465913|ensembl:ENSP00000355180|uniprotkb:O00117|uniprotkb:O00118|uniprotkb:Q14040|uniprotkb:Q14041|uniprotkb:Q16258|uniprotkb:Q7Z645|uniprotkb:Q9BSA8	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:co6a1_human(display_long)|uniprotkb:COL6A1(gene name)|psi-mi:COL6A1(display_short)	psi-mi:"MI:0921"(surface plasmon resonance array)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20724851|imex:IM-26496-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-3893481(chain-parent)	ensembl:ENSG00000142156(gene)|ensembl:ENST00000361866(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005518"(collagen binding)|go:"GO:0005589"(collagen type VI trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0016020"(membrane)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042383"(sarcolemma)|go:"GO:0005576"(extracellular region)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR036465|reactome:R-HSA-1442490|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000178|reactome:R-HSA-419037|reactome:R-HSA-8948216|refseq:NP_001839.2	-	chain-seq-start:22|chain-seq-end:168	-	figure legend:Fig. 9, Suppl. Fig. 7, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rogid:ziEV+a4Xb+C4ioMe8uoISJitR6E9606	rigid:SbzYulHcigLoWEg4ja1gPW9IBu8	false	mutation with no effect:3-3|flag tag:c-c	sufficient binding region:20-256|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14766	uniprotkb:P28300-PRO_0000018520	intact:EBI-947693|uniprotkb:A1L3V1|uniprotkb:P22064|uniprotkb:Q53SD8|uniprotkb:Q53SF3|uniprotkb:Q53SG1|uniprotkb:Q59HF7|uniprotkb:Q8TD95|ensembl:ENSP00000386043	intact:EBI-20724846	psi-mi:ltbp1_human(display_long)|uniprotkb:LTBP1(gene name)|psi-mi:LTBP1(display_short)|uniprotkb:Transforming growth factor beta-1-binding protein 1(gene name synonym)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0921"(surface plasmon resonance array)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20724863|imex:IM-26496-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000618.3|refseq:NP_001159736.1|refseq:NP_001159737.1|refseq:NP_001159738.1|refseq:NP_996826.2|refseq:XP_011531155.1|dip:DIP-50011N|ensembl:ENSG00000049323(gene)|ensembl:ENST00000404816(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0005024"(transforming growth factor beta-activated receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035583"(sequestering of TGFbeta in extracellular matrix)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0050436"(microfibril binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:1901388"(regulation of transforming growth factor beta activation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR017878|interpro:IPR018097|interpro:IPR026823|interpro:IPR036773|mint:Q14766|rcsb pdb:1KSQ|reactome:R-HSA-2129379|reactome:R-HSA-381426|reactome:R-HSA-8957275	intact:EBI-3893481(chain-parent)	-	-	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl. Fig. 7, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	rogid:OgHGfOcQWdQuLUT85Xg04lfggcs9606	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rigid:nqqLD0ssIFuZMDxvOpSh0nghsIw	false	flag tag:c-c|sufficient binding region:873-1037,1079-1328	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13605	uniprotkb:P28300-PRO_0000018520	intact:EBI-5281124|uniprotkb:A7E3X1|uniprotkb:Q3SWX6|ensembl:ENSBTAP00000019854	intact:EBI-20724846	psi-mi:fmod_bovin(display_long)|uniprotkb:FMOD(gene name)|psi-mi:FMOD(display_short)|uniprotkb:Collagen-binding 59 kDa protein(gene name synonym)|uniprotkb:Keratan sulfate proteoglycan fibromodulin(gene name synonym)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0921"(surface plasmon resonance array)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20724876|imex:IM-26496-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_776483.1|ensembl:ENSBTAG00000014912(gene)|ensembl:ENSBTAT00000019854(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR027215|interpro:IPR032675|reactome:R-BTA-2022854|reactome:R-BTA-2022857	intact:EBI-3893481(chain-parent)	-	-	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl. Fig. 7, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	rogid:S52O/y3SsP4GnuqitcE1ro9C7q89913	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rigid:Sf/gMC+HUVrSbxeQDm2B0lfvYqw	false	-	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P01133-PRO_0000007541	uniprotkb:P28300-PRO_0000018520	intact:EBI-9076336	intact:EBI-20724846	psi-mi:p01133-pro_0000007541(display_long)|uniprotkb:EGF(gene name)|psi-mi:EGF(display_short)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0921"(surface plasmon resonance array)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20724884|imex:IM-26496-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-640857(chain-parent)	intact:EBI-3893481(chain-parent)	-	chain-seq-start:971|chain-seq-end:1023	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl. Fig. 7, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	rogid:PwlLsbaKSKke1lpKx0Gyh5RId2w9606	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rigid:GRWsVGa0GOFZiJSv/6DrP+n/RwM	false	-	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y4K0	uniprotkb:P28300-PRO_0000018520	intact:EBI-7172227|ensembl:ENSP00000373783|intact:MINT-4053647|uniprotkb:Q9BW70|uniprotkb:Q53HV3|uniprotkb:Q9Y5Y8|uniprotkb:B2R5Q0	intact:EBI-20724846	psi-mi:loxl2_human(display_long)|uniprotkb:LOXL2(gene name)|psi-mi:LOXL2(display_short)|uniprotkb:Lysyl oxidase-like protein 2(gene name synonym)|uniprotkb:Lysyl oxidase-related protein 2(gene name synonym)|uniprotkb:Lysyl oxidase-related protein WS9-14(gene name synonym)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0921"(surface plasmon resonance array)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20724892|imex:IM-26496-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134013(gene)|ensembl:ENST00000389131(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0004720"(protein-lysine 6-oxidase activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007155"(cell adhesion)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0007568"(aging)|go:"GO:0009055"(electron transfer activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016020"(membrane)|go:"GO:0018057"(peptidyl-lysine oxidation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046688"(response to copper ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0070828"(heterochromatin organization)|go:"GO:1902455"(negative regulation of stem cell population maintenance)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR001695(Lysyl oxidase)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR019828|interpro:IPR036772|mint:Q9Y4K0|rcsb pdb:5ZE3|reactome:R-HSA-1566948|reactome:R-HSA-2243919|go:"GO:0030199"(collagen fibril organization)|refseq:NP_002309.1	intact:EBI-3893481(chain-parent)	-	comment:mint	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl. Fig. 7, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	rogid:F7xjdY5T+JdpyIAsi2BmXPzqz+A9606	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rigid:aYiygADK2Sy+pXTaMJ4pghKHPzU	false	his tag:c-c	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P08253	uniprotkb:P28300-PRO_0000018520	intact:EBI-1033518|uniprotkb:B2R6U1|uniprotkb:Q9UCJ8|ensembl:ENSP00000219070|uniprotkb:E9PE45|uniprotkb:B4DWH3	intact:EBI-20724846	psi-mi:mmp2_human(display_long)|uniprotkb:MMP2(gene name)|psi-mi:MMP2(display_short)|uniprotkb:CLG4A(gene name synonym)|uniprotkb:72 kDa gelatinase(gene name synonym)|uniprotkb:Matrix metalloproteinase-2(gene name synonym)|uniprotkb:Gelatinase A(gene name synonym)|uniprotkb:TBE-1(gene name synonym)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0921"(surface plasmon resonance array)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20724902|imex:IM-26496-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001289437.1|refseq:NP_001289438.1|refseq:NP_001289439.1|ensembl:ENSG00000087245(gene)|ensembl:ENST00000219070(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001955"(blood vessel maturation)|go:"GO:0001957"(intramembranous ossification)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007566"(embryo implantation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030017"(sarcomere)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048771"(tissue remodeling)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071492"(cellular response to UV-A)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR000585(Hemopexin)|interpro:IPR001818(Peptidase M10A and M12B, matrixin and adamalysin)|interpro:IPR002477(Peptidoglycan binding-like)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018486|interpro:IPR018487|interpro:IPR021158|interpro:IPR021190|interpro:IPR024079|interpro:IPR028708|interpro:IPR033739|interpro:IPR036365|interpro:IPR036375|interpro:IPR036943|rcsb pdb:1CK7|rcsb pdb:1CXW|rcsb pdb:1EAK|rcsb pdb:1GEN|rcsb pdb:1GXD|rcsb pdb:1HOV|rcsb pdb:1J7M|rcsb pdb:1KS0|rcsb pdb:1QIB|rcsb pdb:1RTG|rcsb pdb:3AYU|reactome:R-HSA-1442490|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-381426|reactome:R-HSA-3928665|reactome:R-HSA-6785807|reactome:R-HSA-9009391|refseq:NP_001121363.1|refseq:NP_004521.1	intact:EBI-3893481(chain-parent)	-	-	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl. Fig. 7, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	rogid:s0IHoSkzT9GNfkkLZsVsV7cIf1g9606	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rigid:tCdLIaMg6mHOfC2+4cs23PwJZMI	false	sufficient binding region:34-660	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21980	uniprotkb:P28300-PRO_0000018520	intact:EBI-727668|uniprotkb:Q16436|uniprotkb:Q9BTN7|uniprotkb:Q9UH35|uniprotkb:Q6B838|uniprotkb:E1P5V9|ensembl:ENSP00000355330|uniprotkb:Q9H035	intact:EBI-20724846	psi-mi:tgm2_human(display_long)|uniprotkb:TGM2(gene name)|psi-mi:TGM2(display_short)|uniprotkb:Tissue transglutaminase(gene name synonym)|uniprotkb:Transglutaminase C(gene name synonym)|uniprotkb:Transglutaminase-2(gene name synonym)|uniprotkb:Transglutaminase H(gene name synonym)|uniprotkb:Erythrocyte transglutaminase(gene name synonym)|uniprotkb:"Heart G alpha(h)"(gene name synonym)|uniprotkb:Isopeptidase TGM2(gene name synonym)|uniprotkb:"Protein G alpha(h)"(gene name synonym)|uniprotkb:Protein-glutamine deamidase TGM2(gene name synonym)|uniprotkb:Protein-glutamine dopaminyltransferase TGM2(gene name synonym)|uniprotkb:Protein-glutamine histaminyltransferase TGM2(gene name synonym)|uniprotkb:Protein-glutamine noradrenalinyltransferase TGM2(gene name synonym)|uniprotkb:Protein-glutamine serotonyltransferase TGM2(gene name synonym)|uniprotkb:Transglutaminase II(gene name synonym)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0921"(surface plasmon resonance array)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20724912|imex:IM-26496-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004604.2|refseq:NP_945189.1|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008233"(peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0018153"("isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine")|go:"GO:0018277"(protein deamination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031226"(intrinsic component of plasma membrane)|ensembl:ENSG00000198959(gene)|ensembl:ENST00000361475(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003810"(protein-glutamine gamma-glutamyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050568"(protein-glutamine glutaminase activity)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0060348"(bone development)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0060662"(salivary gland cavitation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:0120295"(histone serotonyltransferase activity)|go:"GO:0120297"(histone dopaminyltransferase activity)|go:"GO:0120298"(peptide noradrenalinyltransferase activity)|go:"GO:0120299"(peptide histaminyltransferase activity)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904015"(cellular response to serotonin)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|interpro:IPR001102(Transglutaminase, N-terminal)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR008958(Transglutaminase, C-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013808(Transglutaminase, conserved site)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR023608|interpro:IPR036238|interpro:IPR036985|interpro:IPR038765|mint:P21980|rcsb pdb:1FAU|rcsb pdb:1KV3|rcsb pdb:2Q3Z|rcsb pdb:3LY6|rcsb pdb:3S3J|rcsb pdb:3S3P|rcsb pdb:3S3S|rcsb pdb:4PYG|rcsb pdb:6A8P|rcsb pdb:6KZB|go:"GO:2000425"(regulation of apoptotic cell clearance)|refseq:XP_011527330.1|refseq:NP_001310245.1|dip:DIP-33557N	intact:EBI-3893481(chain-parent)	-	-	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl. Fig. 7, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	rogid:S61on+x/CwI9G/k/0UhS6pFO+wE9606	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rigid:ymctrh/9jnre+tvueJNRy7aq3mY	false	tag:n-n	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21980	uniprotkb:P28300-PRO_0000018520	intact:EBI-727668|uniprotkb:Q16436|uniprotkb:Q9BTN7|uniprotkb:Q9UH35|uniprotkb:Q6B838|uniprotkb:E1P5V9|ensembl:ENSP00000355330|uniprotkb:Q9H035	intact:EBI-20724846	psi-mi:tgm2_human(display_long)|uniprotkb:TGM2(gene name)|psi-mi:TGM2(display_short)|uniprotkb:Tissue transglutaminase(gene name synonym)|uniprotkb:Transglutaminase C(gene name synonym)|uniprotkb:Transglutaminase-2(gene name synonym)|uniprotkb:Transglutaminase H(gene name synonym)|uniprotkb:Erythrocyte transglutaminase(gene name synonym)|uniprotkb:"Heart G alpha(h)"(gene name synonym)|uniprotkb:Isopeptidase TGM2(gene name synonym)|uniprotkb:"Protein G alpha(h)"(gene name synonym)|uniprotkb:Protein-glutamine deamidase TGM2(gene name synonym)|uniprotkb:Protein-glutamine dopaminyltransferase TGM2(gene name synonym)|uniprotkb:Protein-glutamine histaminyltransferase TGM2(gene name synonym)|uniprotkb:Protein-glutamine noradrenalinyltransferase TGM2(gene name synonym)|uniprotkb:Protein-glutamine serotonyltransferase TGM2(gene name synonym)|uniprotkb:Transglutaminase II(gene name synonym)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0921"(surface plasmon resonance array)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20724922|imex:IM-26496-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004604.2|refseq:NP_945189.1|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008233"(peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0018153"("isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine")|go:"GO:0018277"(protein deamination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031226"(intrinsic component of plasma membrane)|ensembl:ENSG00000198959(gene)|ensembl:ENST00000361475(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003810"(protein-glutamine gamma-glutamyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050568"(protein-glutamine glutaminase activity)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0060348"(bone development)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0060662"(salivary gland cavitation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:0120295"(histone serotonyltransferase activity)|go:"GO:0120297"(histone dopaminyltransferase activity)|go:"GO:0120298"(peptide noradrenalinyltransferase activity)|go:"GO:0120299"(peptide histaminyltransferase activity)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904015"(cellular response to serotonin)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|interpro:IPR001102(Transglutaminase, N-terminal)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR008958(Transglutaminase, C-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013808(Transglutaminase, conserved site)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR023608|interpro:IPR036238|interpro:IPR036985|interpro:IPR038765|mint:P21980|rcsb pdb:1FAU|rcsb pdb:1KV3|rcsb pdb:2Q3Z|rcsb pdb:3LY6|rcsb pdb:3S3J|rcsb pdb:3S3P|rcsb pdb:3S3S|rcsb pdb:4PYG|rcsb pdb:6A8P|rcsb pdb:6KZB|go:"GO:2000425"(regulation of apoptotic cell clearance)|refseq:XP_011527330.1|refseq:NP_001310245.1|dip:DIP-33557N	intact:EBI-3893481(chain-parent)	-	-	chain-seq-start:22|chain-seq-end:168	figure legend:Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	rogid:S61on+x/CwI9G/k/0UhS6pFO+wE9606	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rigid:ymctrh/9jnre+tvueJNRy7aq3mY	false	L-histidine residue:n-n|mutation with no effect:277-277	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q4Q597	uniprotkb:P28300-PRO_0000018520	intact:EBI-20724935|ensemblprotists:CAJ08705	intact:EBI-20724846	psi-mi:q4q597_leima(display_long)|uniprotkb:SODB1(gene name)|psi-mi:SODB1(display_short)|uniprotkb:LMJF_32_1820(orf name)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0921"(surface plasmon resonance array)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:5664(leima)|taxid:5664(Leishmania major)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20724949|imex:IM-26496-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblprotists:CAJ08705(transcript)|ensemblprotists:LMJF_32_1820(gene)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0046872"(metal ion binding)|refseq:XP_001685501.1|interpro:IPR001189(Manganese and iron superoxide dismutase)|interpro:IPR019833|interpro:IPR019832|interpro:IPR019831|interpro:IPR036324|interpro:IPR036314	intact:EBI-3893481(chain-parent)	-	-	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl. Fig. 7, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	rogid:Kn2CRZGE7QH4fpmfdq14Av3wX8E5664	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rigid:yLYVr00SzUQdGR9oce/IWfMP1NI	false	flag tag:c-c	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H6X2-2	uniprotkb:P28300-PRO_0000018520	intact:EBI-905659|ensembl:ENSP00000386494	intact:EBI-20724846	psi-mi:q9h6x2-2(display_long)|uniprotkb:ANTXR1(gene name)|psi-mi:ANTXR1(display_short)|uniprotkb:ATR(gene name synonym)|uniprotkb:TEM8(gene name synonym)|uniprotkb:Tumor endothelial marker 8(gene name synonym)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0921"(surface plasmon resonance array)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20724959|imex:IM-26496-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-905643(antr1_human)|ensembl:ENSG00000169604(gene)|ensembl:ENST00000409349(transcript)	intact:EBI-3893481(chain-parent)	-	-	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl. Fig. 7, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	rogid:Zf4W6+r4NcIRwEQGEnaj5oENeak9606	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rigid:ULtY5JyHRrez/74a92WKUu1BPbY	false	glutathione s tranferase tag:n-n	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:37397"	uniprotkb:P28300-PRO_0000018520	intact:EBI-9673920|chebi:"CHEBI:23224"|chebi:"CHEBI:3676"	intact:EBI-20724846	psi-mi:chondroitin sulfate-1(display_short)|psi-mi:"CHEBI:37397"(display_long)|intact:chondroitin polysulfate(synonym)|intact:Chondroitin sulfate(synonym)|intact:chondroitin sulfates(synonym)|intact:chondroitin sulfuric acid(synonym)|intact:chondroitin sulphate(synonym)|intact:Chondroitinsulfat(synonym)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0921"(surface plasmon resonance array)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20724969|imex:IM-26496-44	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	intact:EBI-3893481(chain-parent)	-	-	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl. Fig. 7, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	-	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	-	false	-	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:18376"	uniprotkb:P28300-PRO_0000018520	intact:EBI-2566541	intact:EBI-20724846	psi-mi:dermatan_sulfate(display_short)|psi-mi:"CHEBI:18376"(display_long)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0921"(surface plasmon resonance array)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20724977|imex:IM-26496-46	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	matrixdb:GAG_3(source reference)	intact:EBI-3893481(chain-parent)	-	-	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl. Fig. 7, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	-	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	-	false	-	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:28815"	uniprotkb:P28300-PRO_0000018520	intact:EBI-2566501	intact:EBI-20724846	psi-mi:heparan_sulfate(display_short)|psi-mi:"CHEBI:28815"(display_long)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0921"(surface plasmon resonance array)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20724985|imex:IM-26496-48	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	matrixdb:GAG_2(source reference)	intact:EBI-3893481(chain-parent)	-	-	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl. Fig. 7, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	-	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	-	false	-	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16336"	uniprotkb:P28300-PRO_0000018520	intact:EBI-2566617	intact:EBI-20724846	psi-mi:hyaluronan(display_short)|psi-mi:"CHEBI:16336"(display_long)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0921"(surface plasmon resonance array)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20724993|imex:IM-26496-50	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	matrixdb:GAG_9(source reference)	intact:EBI-3893481(chain-parent)	-	-	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl. Fig. 7, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	-	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	-	false	-	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07507	uniprotkb:P28300-PRO_0000018520	intact:EBI-719535|uniprotkb:Q8N4R2|uniprotkb:Q9UIX8|uniprotkb:A8K981|ensembl:ENSP00000356791	intact:EBI-20724846	psi-mi:derm_human(display_long)|uniprotkb:Tyrosine-rich acidic matrix protein(gene name synonym)|uniprotkb:DPT(gene name)|psi-mi:DPT(display_short)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0921"(surface plasmon resonance array)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20725001|imex:IM-26496-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001928.2|ensembl:ENSG00000143196(gene)|ensembl:ENST00000367817(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR026645	intact:EBI-3893481(chain-parent)	-	-	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	rogid:Su6FIKMifD6sS+iYZTzwJqrLvg09606	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rigid:0gzV/7KwyjPj5VOWH+GOJONxrIU	false	tag:n-n	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P02751	uniprotkb:P28300-PRO_0000018520	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839	intact:EBI-20724846	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0921"(surface plasmon resonance array)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20725011|imex:IM-26496-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223	intact:EBI-3893481(chain-parent)	-	-	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/10/18	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rigid:IFb9YLI0WnvKb0jLCorPhgabcIM	false	-	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P02751-PRO_0000390479	uniprotkb:P28300-PRO_0000018520	intact:EBI-15482592	intact:EBI-20724846	psi-mi:p02751-pro_0000390479(display_long)|uniprotkb:Cold-insoluble globulin(gene name synonym)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0921"(surface plasmon resonance array)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20725019|imex:IM-26496-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1220319(chain-parent)	intact:EBI-3893481(chain-parent)	-	chain-seq-start:627|chain-seq-end:702	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	rogid:gW2sIQCKhD7/tgkQMo1YOQ1a9NM9606	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rigid:NB9R0lOGWYSkdvmIbb5eeeSz0To	false	-	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:28304"	uniprotkb:P28300-PRO_0000018520	intact:EBI-1379423	intact:EBI-20724846	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0921"(surface plasmon resonance array)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20725027|imex:IM-26496-52	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	intact:EBI-3893481(chain-parent)	-	-	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	-	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	-	false	-	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P00747	uniprotkb:P28300-PRO_0000018520	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938	intact:EBI-20724846	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0921"(surface plasmon resonance array)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20725035|imex:IM-26496-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000292.1|ensembl:ENSG00000122194(gene)|ensembl:ENST00000308192(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1990405"(protein antigen binding)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205	intact:EBI-3893481(chain-parent)	-	-	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rigid:LH8FG9KDHuYc7q1oYM6Jlc/wMQQ	false	-	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
reactome:R-HSA-2089970	uniprotkb:P28300-PRO_0000018520	intact:EBI-2325312|matrixdb:MULT_3_human|reactome:R-HSA-2467139|reactome:R-HSA-2396132|reactome:R-HSA-2396423|reactome:R-HSA-2396135|reactome:R-HSA-2396296|reactome:R-HSA-2396322|reactome:R-HSA-2428941|reactome:R-HSA-2396033|reactome:R-HSA-2396048	intact:EBI-20724846	psi-mi:collagen_i_human(display_short)|psi-mi:R-HSA-2089970(display_long)|intact:Collagen type I trimer(complex recommended name)|intact:Type I collagen(complex synonym)|intact:"2xCOL1A1:COL1A2"(complex systematic name)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0921"(surface plasmon resonance array)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20725043|imex:IM-26496-54	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:1302"(stable complex)	psi-mi:"MI:0326"(protein)	pubmed:1916105(see-also)|pubmed:17876790(see-also)|complex portal:CPX-1650(complex-primary)|intact:EBI-25750246(exp-evidence)|go:"GO:0005584"(collagen type I trimer)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0030199"(collagen fibril organization)|evidence ontology:"ECO:0000353"	intact:EBI-3893481(chain-parent)	-	curated-complex:Forms the fibrils of tendon, ligaments and bones, also present in skin. In bones the fibrils are mineralized with calcium hydroxyapatite.|assembly:Heterotrimer|complex-properties:"Triple-helices consisting of about 1000 amino acids per chain forming a coiled coil structure. Each polypeptide forms a left-handed helix in which every third residue, glycine, comes into the center of the superhelix. Propeptides (telopeptides) at both ends of the molecular precursor undergo highly complex fibrillogenesis."	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	-	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	-	false	-	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P01133-PRO_0000007541	uniprotkb:P28300-PRO_0000018520	intact:EBI-9076336	intact:EBI-20724846	psi-mi:p01133-pro_0000007541(display_long)|uniprotkb:EGF(gene name)|psi-mi:EGF(display_short)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20725066|imex:IM-26496-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-640857(chain-parent)	intact:EBI-3893481(chain-parent)	-	chain-seq-start:971|chain-seq-end:1023	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	rogid:PwlLsbaKSKke1lpKx0Gyh5RId2w9606	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rigid:GRWsVGa0GOFZiJSv/6DrP+n/RwM	false	-	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21980	uniprotkb:P28300-PRO_0000018520	intact:EBI-727668|uniprotkb:Q16436|uniprotkb:Q9BTN7|uniprotkb:Q9UH35|uniprotkb:Q6B838|uniprotkb:E1P5V9|ensembl:ENSP00000355330|uniprotkb:Q9H035	intact:EBI-20724846	psi-mi:tgm2_human(display_long)|uniprotkb:TGM2(gene name)|psi-mi:TGM2(display_short)|uniprotkb:Tissue transglutaminase(gene name synonym)|uniprotkb:Transglutaminase C(gene name synonym)|uniprotkb:Transglutaminase-2(gene name synonym)|uniprotkb:Transglutaminase H(gene name synonym)|uniprotkb:Erythrocyte transglutaminase(gene name synonym)|uniprotkb:"Heart G alpha(h)"(gene name synonym)|uniprotkb:Isopeptidase TGM2(gene name synonym)|uniprotkb:"Protein G alpha(h)"(gene name synonym)|uniprotkb:Protein-glutamine deamidase TGM2(gene name synonym)|uniprotkb:Protein-glutamine dopaminyltransferase TGM2(gene name synonym)|uniprotkb:Protein-glutamine histaminyltransferase TGM2(gene name synonym)|uniprotkb:Protein-glutamine noradrenalinyltransferase TGM2(gene name synonym)|uniprotkb:Protein-glutamine serotonyltransferase TGM2(gene name synonym)|uniprotkb:Transglutaminase II(gene name synonym)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20725078|imex:IM-26496-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004604.2|refseq:NP_945189.1|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008233"(peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0018153"("isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine")|go:"GO:0018277"(protein deamination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031226"(intrinsic component of plasma membrane)|ensembl:ENSG00000198959(gene)|ensembl:ENST00000361475(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003810"(protein-glutamine gamma-glutamyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050568"(protein-glutamine glutaminase activity)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0060348"(bone development)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0060662"(salivary gland cavitation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:0120295"(histone serotonyltransferase activity)|go:"GO:0120297"(histone dopaminyltransferase activity)|go:"GO:0120298"(peptide noradrenalinyltransferase activity)|go:"GO:0120299"(peptide histaminyltransferase activity)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904015"(cellular response to serotonin)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|interpro:IPR001102(Transglutaminase, N-terminal)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR008958(Transglutaminase, C-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013808(Transglutaminase, conserved site)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR023608|interpro:IPR036238|interpro:IPR036985|interpro:IPR038765|mint:P21980|rcsb pdb:1FAU|rcsb pdb:1KV3|rcsb pdb:2Q3Z|rcsb pdb:3LY6|rcsb pdb:3S3J|rcsb pdb:3S3P|rcsb pdb:3S3S|rcsb pdb:4PYG|rcsb pdb:6A8P|rcsb pdb:6KZB|go:"GO:2000425"(regulation of apoptotic cell clearance)|refseq:XP_011527330.1|refseq:NP_001310245.1|dip:DIP-33557N	intact:EBI-3893481(chain-parent)	-	-	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	rogid:S61on+x/CwI9G/k/0UhS6pFO+wE9606	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rigid:ymctrh/9jnre+tvueJNRy7aq3mY	false	tag:n-n	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P02751-PRO_0000390479	uniprotkb:P28300-PRO_0000018520	intact:EBI-15482592	intact:EBI-20724846	psi-mi:p02751-pro_0000390479(display_long)|uniprotkb:Cold-insoluble globulin(gene name synonym)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20725096|imex:IM-26496-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1220319(chain-parent)	intact:EBI-3893481(chain-parent)	-	chain-seq-start:627|chain-seq-end:702	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	rogid:gW2sIQCKhD7/tgkQMo1YOQ1a9NM9606	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rigid:NB9R0lOGWYSkdvmIbb5eeeSz0To	false	-	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:28304"	uniprotkb:P28300-PRO_0000018520	intact:EBI-1379423	intact:EBI-20724846	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20725104|imex:IM-26496-56	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	intact:EBI-3893481(chain-parent)	-	-	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	-	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	-	false	-	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
reactome:R-HSA-2089970	uniprotkb:P28300-PRO_0000018520	intact:EBI-2325312|matrixdb:MULT_3_human|reactome:R-HSA-2467139|reactome:R-HSA-2396132|reactome:R-HSA-2396423|reactome:R-HSA-2396135|reactome:R-HSA-2396296|reactome:R-HSA-2396322|reactome:R-HSA-2428941|reactome:R-HSA-2396033|reactome:R-HSA-2396048	intact:EBI-20724846	psi-mi:collagen_i_human(display_short)|psi-mi:R-HSA-2089970(display_long)|intact:Collagen type I trimer(complex recommended name)|intact:Type I collagen(complex synonym)|intact:"2xCOL1A1:COL1A2"(complex systematic name)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20725112|imex:IM-26496-58	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:1302"(stable complex)	psi-mi:"MI:0326"(protein)	pubmed:1916105(see-also)|pubmed:17876790(see-also)|complex portal:CPX-1650(complex-primary)|intact:EBI-25750246(exp-evidence)|go:"GO:0005584"(collagen type I trimer)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0030199"(collagen fibril organization)|evidence ontology:"ECO:0000353"	intact:EBI-3893481(chain-parent)	-	curated-complex:Forms the fibrils of tendon, ligaments and bones, also present in skin. In bones the fibrils are mineralized with calcium hydroxyapatite.|assembly:Heterotrimer|complex-properties:"Triple-helices consisting of about 1000 amino acids per chain forming a coiled coil structure. Each polypeptide forms a left-handed helix in which every third residue, glycine, comes into the center of the superhelix. Propeptides (telopeptides) at both ends of the molecular precursor undergo highly complex fibrillogenesis."	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl. Fig. 8A, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	-	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	-	false	-	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07507	uniprotkb:P28300-PRO_0000018520	intact:EBI-719535|uniprotkb:Q8N4R2|uniprotkb:Q9UIX8|uniprotkb:A8K981|ensembl:ENSP00000356791	intact:EBI-20724846	psi-mi:derm_human(display_long)|uniprotkb:Tyrosine-rich acidic matrix protein(gene name synonym)|uniprotkb:DPT(gene name)|psi-mi:DPT(display_short)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20725120|imex:IM-26496-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001928.2|ensembl:ENSG00000143196(gene)|ensembl:ENST00000367817(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR026645	intact:EBI-3893481(chain-parent)	-	-	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl. Fig. 8A, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/08/05	rogid:Su6FIKMifD6sS+iYZTzwJqrLvg09606	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rigid:0gzV/7KwyjPj5VOWH+GOJONxrIU	false	tag:n-n	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P02751	uniprotkb:P28300-PRO_0000018520	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839	intact:EBI-20724846	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20725130|imex:IM-26496-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223	intact:EBI-3893481(chain-parent)	-	-	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl. Fig. 8A, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/28	2019/10/18	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rigid:IFb9YLI0WnvKb0jLCorPhgabcIM	false	-	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P00747	uniprotkb:P28300-PRO_0000018520	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938	intact:EBI-20724846	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20725138|imex:IM-26496-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000292.1|ensembl:ENSG00000122194(gene)|ensembl:ENST00000308192(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1990405"(protein antigen binding)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205	intact:EBI-3893481(chain-parent)	-	-	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl Fig. 8B, Table 3, Suppl Table 7|comment:"The model used to calculate kon, koff and kd is a two-state model (Biaeval software)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:2.14x10^-3 ~0.05(second -1)|kon:4.17x10^4 ~0.74(per mole per second)|koff:5.15x10^-3 ~0.21(second -1)|koff:3.06x10^-4 ~0.16(second -1)|kd:15.8x10^-9 ~1.75(molar)	2018/08/28	2019/08/05	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rigid:LH8FG9KDHuYc7q1oYM6Jlc/wMQQ	false	-	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P15502	uniprotkb:P28300-PRO_0000018520	intact:EBI-1222108|uniprotkb:O15336|uniprotkb:O15337|uniprotkb:Q14233|uniprotkb:Q14234|uniprotkb:Q14235|uniprotkb:Q14238|uniprotkb:Q6P0L4|uniprotkb:Q6ZWJ6|uniprotkb:Q75MU5|uniprotkb:Q7Z316|uniprotkb:Q7Z3F5|uniprotkb:Q9UMF5|uniprotkb:B3KTS6	intact:EBI-20724846	psi-mi:eln_human(display_long)|uniprotkb:ELN(gene name)|psi-mi:ELN(display_short)|uniprotkb:Tropoelastin(gene name synonym)	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20725152|imex:IM-26496-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000492.2|refseq:NP_001075221.1|refseq:NP_001075222.1|refseq:NP_001075223.1|refseq:NP_001075224.1|interpro:IPR003979(Tropoelastin)|refseq:NP_001265868.1|reactome:R-HSA-1474228|reactome:R-HSA-1566948|reactome:R-HSA-2129379|refseq:NP_001265844.1|refseq:NP_001265845.1|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008015"(blood circulation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071953"(elastic fiber)	intact:EBI-3893481(chain-parent)	-	-	chain-seq-start:22|chain-seq-end:168	figure legend:Fig. 9, Suppl Fig. 8B, Table 3, Suppl Table 7|comment:"The model used to calculate kon, koff and kd is a two-state model (Biaeval software)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:3.31x10^2(per mole per second)|kon:3.0x10^-3(second -1)|koff:3.1x10^-7(second -1)|koff:4.3x10^-3(second -1)|kd:1.39x10^-9(molar)	2018/08/28	2019/08/05	rogid:rcemQpnE9Kkpsfth+H0n1QU0YZ09606	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rigid:empdHph/cPjkZdkLayIGNscnjG4	false	-	mutation with no effect:3-3|flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28300-PRO_0000018520	uniprotkb:P02751-PRO_0000390479	intact:EBI-20724846	intact:EBI-15482592	psi-mi:p28300-pro_0000018520(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)	psi-mi:p02751-pro_0000390479(display_long)|uniprotkb:Cold-insoluble globulin(gene name synonym)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)	psi-mi:"MI:0969"(bio-layer interferometry)	Vallet et al. (2018)	pubmed:30082873|imex:IM-26496	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-20725173|imex:IM-26496-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-3893481(chain-parent)	intact:EBI-1220319(chain-parent)	-	chain-seq-start:22|chain-seq-end:168	chain-seq-start:627|chain-seq-end:702	figure legend:Fig. 9, Suppl Fig. 8B, Table 3, Suppl Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:2.93x10^3(per mole per second)|koff:4.45x10^-4(second -1)|kd:152.0x10^-9(molar)	2018/08/28	2019/08/05	rogid:eyNXTXFvaP8CpcDyWfifMGWajt09606	rogid:gW2sIQCKhD7/tgkQMo1YOQ1a9NM9606	rigid:NB9R0lOGWYSkdvmIbb5eeeSz0To	false	flag tag:c-c|mutation with no effect:3-3	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)