#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9UM13	uniprotkb:Q9BS18	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-2555953|uniprotkb:Q9Y3V0|ensembl:ENSP00000346987|ensembl:ENSP00000421760|ensembl:ENSP00000421842|ensembl:ENSP00000427327	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:apc13_human(display_long)|uniprotkb:ANAPC13(gene name)|psi-mi:ANAPC13(display_short)|uniprotkb:Cyclosome subunit 13(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726116|wwpdb:5LCW|imex:IM-26717-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	refseq:NP_001229303.1|refseq:NP_001229304.1|refseq:NP_056206.1|ensembl:ENSG00000129055(gene)|ensembl:ENST00000354910(transcript)|ensembl:ENST00000510994(transcript)|ensembl:ENST00000511751(transcript)|ensembl:ENST00000514612(transcript)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR008401(Apc13p)|rcsb pdb:4UI9|rcsb pdb:5G04|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-983168|dip:DIP-56455N	-	-	-	figure legend:Figure 1, Extended data table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2018/08/30	2018/08/30	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:DzS3HXVX7XOfeBlN6uTD51Iek7Q9606	rigid:OPPjzSexE7Pdib1sDVbx+dvIfqM	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q9UM13	uniprotkb:Q96DE5	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-2555937|ensembl:ENSP00000299381|ensembl:ENSP00000477760	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:apc16_human(display_long)|uniprotkb:C10orf104(gene name synonym)|uniprotkb:Cyclosome subunit 16(gene name synonym)|uniprotkb:ANAPC16(gene name)|psi-mi:ANAPC16(display_short)|uniprotkb:CENP-27(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726116|wwpdb:5LCW|imex:IM-26717-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	refseq:NP_001229475.1|refseq:NP_001229476.1|refseq:NP_775744.1|ensembl:ENSG00000166295(gene)|ensembl:ENST00000299381(transcript)|ensembl:ENST00000621663(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0051301"(cell division)|interpro:IPR029641|mint:Q96DE5|rcsb pdb:4RG6|rcsb pdb:4RG9|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|dip:DIP-56449N	-	-	-	figure legend:Figure 1, Extended data table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2018/08/30	2018/08/30	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:THae4cAe47vuWr79Lo0BoGbQY/I9606	rigid:OPPjzSexE7Pdib1sDVbx+dvIfqM	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q9UM13	uniprotkb:Q9H1A4	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-395918|uniprotkb:Q2M3H8|uniprotkb:Q9BSE6|uniprotkb:Q9H8D0|ensembl:ENSP00000339109	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:apc1_human(display_long)|uniprotkb:ANAPC1(gene name)|psi-mi:ANAPC1(display_short)|uniprotkb:TSG24(gene name synonym)|uniprotkb:Cyclosome subunit 1(gene name synonym)|uniprotkb:Testis-specific gene 24 protein(gene name synonym)|uniprotkb:Mitotic checkpoint regulator(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726116|wwpdb:5LCW|imex:IM-26717-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	refseq:NP_073153.1|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENSG00000153107(gene)|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|ensembl:ENST00000341068(transcript)|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5L9U|go:"GO:0005680"(anaphase-promoting complex)|rcsb pdb:5LCW|go:"GO:0005829"(cytosol)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|rcsb pdb:5LGG|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|interpro:IPR011989(Armadillo-like helical)|interpro:IPR024990|interpro:IPR041221|mint:Q9H1A4|dip:DIP-32940N	-	-	-	figure legend:Figure 1, Extended data table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2018/08/30	2018/08/30	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:GCcoaN+24WplwiaqcHwHsjyWn789606	rigid:OPPjzSexE7Pdib1sDVbx+dvIfqM	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q9UM13	uniprotkb:Q12834	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-367462|uniprotkb:Q5JUY4|uniprotkb:Q9BW56|uniprotkb:Q9UQI9|uniprotkb:B2R6Z6|uniprotkb:D3DPJ1|ensembl:ENSP00000308450|ensembl:ENSP00000361540	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:cdc20_human(display_long)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:p55CDC(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726116|wwpdb:5LCW|imex:IM-26717-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	rcsb pdb:6Q6H|reactome:R-HSA-141405|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174048|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176417|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-5689880|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983168|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051301"(cell division)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q12834|rcsb pdb:4GGA|rcsb pdb:4GGC|rcsb pdb:4GGD|rcsb pdb:4N14|rcsb pdb:5G04|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5LCW|rcsb pdb:6F0X|rcsb pdb:6Q6G|refseq:NP_001246.2|ensembl:ENSG00000117399(gene)|ensembl:ENST00000310955(transcript)|ensembl:ENST00000372462(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-29655N	-	-	-	figure legend:Figure 1, Extended data table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2018/08/30	2018/08/30	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:15j9Heovw6LpbClp5kT9Wz6a88A9606	rigid:OPPjzSexE7Pdib1sDVbx+dvIfqM	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q9UM13	uniprotkb:Q12834	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-367462|uniprotkb:Q5JUY4|uniprotkb:Q9BW56|uniprotkb:Q9UQI9|uniprotkb:B2R6Z6|uniprotkb:D3DPJ1|ensembl:ENSP00000308450|ensembl:ENSP00000361540	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:cdc20_human(display_long)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:p55CDC(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726116|wwpdb:5LCW|imex:IM-26717-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	rcsb pdb:6Q6H|reactome:R-HSA-141405|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174048|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176417|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-5689880|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983168|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051301"(cell division)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q12834|rcsb pdb:4GGA|rcsb pdb:4GGC|rcsb pdb:4GGD|rcsb pdb:4N14|rcsb pdb:5G04|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5LCW|rcsb pdb:6F0X|rcsb pdb:6Q6G|refseq:NP_001246.2|ensembl:ENSG00000117399(gene)|ensembl:ENST00000310955(transcript)|ensembl:ENST00000372462(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-29655N	-	-	-	figure legend:Figure 1, Extended data table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2018/08/30	2018/08/30	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:15j9Heovw6LpbClp5kT9Wz6a88A9606	rigid:OPPjzSexE7Pdib1sDVbx+dvIfqM	false	-	his tag:n-n|maltose binding protein tag:n-n	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q9UM13	uniprotkb:Q8NHZ8	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-2555941|ensembl:ENSP00000363322	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:cdc26_human(display_long)|uniprotkb:ANAPC12(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 12(gene name synonym)|uniprotkb:C9orf17(gene name synonym)|uniprotkb:Cell division cycle protein 26 homolog(gene name synonym)|uniprotkb:CDC26(gene name)|psi-mi:CDC26(display_short)	psi-mi:"MI:0410"(3D electron microscopy)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726116|wwpdb:5LCW|imex:IM-26717-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	dip:DIP-48551N|refseq:NP_644815.1|ensembl:ENSG00000176386(gene)|ensembl:ENST00000374206(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR018860|mint:Q8NHZ8|rcsb pdb:3HYM|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-174048|reactome:R-HSA-69017|reactome:R-HSA-174084|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|refseq:XP_016870062.1|refseq:XP_016870063.1|refseq:XP_016870064.1	-	-	-	figure legend:Figure 1, Extended data table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2018/08/30	2018/08/30	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:cEo8S5g8dgb5r54+8FFc8ZFcCB09606	rigid:OPPjzSexE7Pdib1sDVbx+dvIfqM	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q9UM13	uniprotkb:O60566-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725951	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:o60566-1(display_long)|uniprotkb:BUB1B(gene name)|psi-mi:BUB1B(display_short)|uniprotkb:BUBR1(gene name synonym)|uniprotkb:MAD3L(gene name synonym)|uniprotkb:SSK1(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726116|wwpdb:5LCW|imex:IM-26717-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:O60566-1(isoform-parent)	-	-	-	figure legend:Figure 1, Extended data table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2018/08/30	2018/08/30	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:EgsQ2ZywEJ+r8hd95vcNEyikMBA9606	rigid:OPPjzSexE7Pdib1sDVbx+dvIfqM	false	-	flag tag:n-n|strep ii tag:c-c	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q9UM13	uniprotkb:P30260-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725924|ensembl:ENSP00000066544	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:p30260-1(display_long)|uniprotkb:CDC27(gene name)|psi-mi:CDC27(display_short)|uniprotkb:ANAPC3(gene name synonym)|uniprotkb:D0S1430E(gene name synonym)|uniprotkb:D17S978E(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 3(gene name synonym)|uniprotkb:CDC27 homolog(gene name synonym)|uniprotkb:H-NUC(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726116|wwpdb:5LCW|imex:IM-26717-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	ensembl:ENSG00000004897(gene)|ensembl:ENST00000066544(transcript)|uniprotkb:P30260-1(isoform-parent)|intact:EBI-994813(isoform-parent)	-	-	-	figure legend:Figure 1, Extended data table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2018/08/30	2018/08/30	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:YOrJCRal5ZfO7kP2b8FPon0Yytw9606	rigid:OPPjzSexE7Pdib1sDVbx+dvIfqM	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q9UM13	uniprotkb:P60006-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725917	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:p60006-1(display_long)|uniprotkb:ANAPC15(gene name)|psi-mi:ANAPC15(display_short)|uniprotkb:C11orf51(gene name synonym)|uniprotkb:HSPC020(orf name)	psi-mi:"MI:0410"(3D electron microscopy)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726116|wwpdb:5LCW|imex:IM-26717-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:P60006-1(isoform-parent)	-	-	-	figure legend:Figure 1, Extended data table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2018/08/30	2018/08/30	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:nQTEwP1LHxaqHPJEYm/gr3bCi649606	rigid:OPPjzSexE7Pdib1sDVbx+dvIfqM	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q9UM13	uniprotkb:Q13042-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-15798699|ensembl:ENSP00000348554|ensembl:ENSP00000353549	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q13042-1(display_long)|uniprotkb:CDC16(gene name)|psi-mi:CDC16(display_short)|uniprotkb:ANAPC6(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 6(gene name synonym)|uniprotkb:CDC16 homolog(gene name synonym)|uniprotkb:Cyclosome subunit 6(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726116|wwpdb:5LCW|imex:IM-26717-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	ensembl:ENSG00000130177(gene)|ensembl:ENST00000356221(transcript)|ensembl:ENST00000360383(transcript)|intact:EBI-994830(isoform-parent)	-	-	-	figure legend:Figure 1, Extended data table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2018/08/30	2018/08/30	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:AAG0s18JHrn+M5dG7T/N6t0Y97w9606	rigid:OPPjzSexE7Pdib1sDVbx+dvIfqM	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q9UM13	uniprotkb:Q13257-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20724396|ensembl:ENSP00000296509	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q13257-1(display_long)|uniprotkb:Mitotic arrest deficient 2-like protein 1(gene name synonym)|uniprotkb:MAD2L1(gene name)|psi-mi:MAD2L1(display_short)|uniprotkb:MAD2(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726116|wwpdb:5LCW|imex:IM-26717-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	ensembl:ENSG00000164109(gene)|ensembl:ENST00000296509(transcript)|intact:EBI-78203(isoform-parent)	-	-	-	figure legend:Figure 1, Extended data table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2018/08/30	2018/08/30	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:FyL1tmJllOZ4gQvwWb96aV9PMFw9606	rigid:OPPjzSexE7Pdib1sDVbx+dvIfqM	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q9UM13	uniprotkb:Q9NYG5-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725905|ensembl:ENSP00000339695|ensembl:ENSP00000376181|ensembl:ENSP00000458143|ensembl:ENSP00000458265|ensembl:ENSP00000458515|ensembl:ENSP00000459200|ensembl:ENSP00000460064|ensembl:ENSP00000460678|ensembl:ENSP00000461648|ensembl:ENSP00000463567|ensembl:ENSP00000463598|ensembl:ENSP00000463640|ensembl:ENSP00000464615	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9nyg5-1(display_long)|uniprotkb:ANAPC11(gene name)|psi-mi:ANAPC11(display_short)|uniprotkb:Cyclosome subunit 11(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated RING finger protein(gene name synonym)|uniprotkb:HSPC214(orf name)	psi-mi:"MI:0410"(3D electron microscopy)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726116|wwpdb:5LCW|imex:IM-26717-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9NYG5-1(isoform-parent)|intact:EBI-2130187(isoform-parent)|ensembl:ENSG00000141552(gene)|ensembl:ENST00000344877(transcript)|ensembl:ENST00000392376(transcript)|ensembl:ENST00000571024(transcript)|ensembl:ENST00000571570(transcript)|ensembl:ENST00000571874(transcript)|ensembl:ENST00000572639(transcript)|ensembl:ENST00000572851(transcript)|ensembl:ENST00000574924(transcript)|ensembl:ENST00000575195(transcript)|ensembl:ENST00000577747(transcript)|ensembl:ENST00000578550(transcript)|ensembl:ENST00000579978(transcript)|ensembl:ENST00000583839(transcript)	-	-	-	figure legend:Figure 1, Extended data table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2018/08/30	2018/08/30	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:xG99MtTrPkKxJX1gHacApUDhmt49606	rigid:OPPjzSexE7Pdib1sDVbx+dvIfqM	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q9UM13	uniprotkb:Q9UJX2-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725911	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx2-1(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726116|wwpdb:5LCW|imex:IM-26717-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX2-1(isoform-parent)	-	-	-	figure legend:Figure 1, Extended data table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2018/08/30	2018/08/30	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606	rigid:OPPjzSexE7Pdib1sDVbx+dvIfqM	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q9UM13	uniprotkb:Q9UJX3-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725898	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx3-1(display_long)|uniprotkb:ANAPC7(gene name)|psi-mi:ANAPC7(display_short)|uniprotkb:APC7(gene name synonym)|uniprotkb:Cyclosome subunit 7(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726116|wwpdb:5LCW|imex:IM-26717-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	intact:EBI-1384164(isoform-parent)	-	-	-	figure legend:Figure 1, Extended data table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2018/08/30	2018/08/30	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:2q+llvuIzK2MOWjPuOUxmyN782E9606	rigid:OPPjzSexE7Pdib1sDVbx+dvIfqM	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q9UM13	uniprotkb:Q9UJX4-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725945	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx4-1(display_long)|uniprotkb:ANAPC5(gene name)|psi-mi:ANAPC5(display_short)|uniprotkb:APC5(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726116|wwpdb:5LCW|imex:IM-26717-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX4-1(isoform-parent)	-	-	-	figure legend:Figure 1, Extended data table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2018/08/30	2018/08/30	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:Bg/ZL1IEXYdO6XblNQvxjhVX9tI9606	rigid:OPPjzSexE7Pdib1sDVbx+dvIfqM	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q9UM13	uniprotkb:Q9UJX5-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725932	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx5-1(display_long)|uniprotkb:ANAPC4(gene name)|psi-mi:ANAPC4(display_short)|uniprotkb:APC4(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726116|wwpdb:5LCW|imex:IM-26717-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX5-1(isoform-parent)	-	-	-	figure legend:Figure 1, Extended data table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2018/08/30	2018/08/30	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:c3Z2ioMzMExZK39sLFZCSaAFW9M9606	rigid:OPPjzSexE7Pdib1sDVbx+dvIfqM	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q9UM13	uniprotkb:Q9UJX6-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725938	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx6-1(display_long)|uniprotkb:ANAPC2(gene name)|psi-mi:ANAPC2(display_short)|uniprotkb:APC2(gene name synonym)|uniprotkb:KIAA1406(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726116|wwpdb:5LCW|imex:IM-26717-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX6-1(isoform-parent)	-	-	-	figure legend:Figure 1, Extended data table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs)	-	2018/08/30	2018/08/30	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:PVV9qYjevihqygZjLzBflQ0Ob409606	rigid:OPPjzSexE7Pdib1sDVbx+dvIfqM	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q9UM13	uniprotkb:Q9H1A4	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-395918|uniprotkb:Q2M3H8|uniprotkb:Q9BSE6|uniprotkb:Q9H8D0|ensembl:ENSP00000339109	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:apc1_human(display_long)|uniprotkb:ANAPC1(gene name)|psi-mi:ANAPC1(display_short)|uniprotkb:TSG24(gene name synonym)|uniprotkb:Cyclosome subunit 1(gene name synonym)|uniprotkb:Testis-specific gene 24 protein(gene name synonym)|uniprotkb:Mitotic checkpoint regulator(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726212|imex:IM-26717-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	refseq:NP_073153.1|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENSG00000153107(gene)|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|ensembl:ENST00000341068(transcript)|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5L9U|go:"GO:0005680"(anaphase-promoting complex)|rcsb pdb:5LCW|go:"GO:0005829"(cytosol)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|rcsb pdb:5LGG|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|interpro:IPR011989(Armadillo-like helical)|interpro:IPR024990|interpro:IPR041221|mint:Q9H1A4|dip:DIP-32940N	-	-	-	figure legend:Extended data figure 1a, Extended data figure 1k|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:GCcoaN+24WplwiaqcHwHsjyWn789606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q12834	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-367462|uniprotkb:Q5JUY4|uniprotkb:Q9BW56|uniprotkb:Q9UQI9|uniprotkb:B2R6Z6|uniprotkb:D3DPJ1|ensembl:ENSP00000308450|ensembl:ENSP00000361540	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:cdc20_human(display_long)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:p55CDC(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726212|imex:IM-26717-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	rcsb pdb:6Q6H|reactome:R-HSA-141405|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174048|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176417|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-5689880|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983168|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051301"(cell division)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q12834|rcsb pdb:4GGA|rcsb pdb:4GGC|rcsb pdb:4GGD|rcsb pdb:4N14|rcsb pdb:5G04|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5LCW|rcsb pdb:6F0X|rcsb pdb:6Q6G|refseq:NP_001246.2|ensembl:ENSG00000117399(gene)|ensembl:ENST00000310955(transcript)|ensembl:ENST00000372462(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-29655N	-	-	-	figure legend:Extended data figure 1a, Extended data figure 1k|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:15j9Heovw6LpbClp5kT9Wz6a88A9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:O60566-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725951	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:o60566-1(display_long)|uniprotkb:BUB1B(gene name)|psi-mi:BUB1B(display_short)|uniprotkb:BUBR1(gene name synonym)|uniprotkb:MAD3L(gene name synonym)|uniprotkb:SSK1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726212|imex:IM-26717-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:O60566-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1a, Extended data figure 1k|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:EgsQ2ZywEJ+r8hd95vcNEyikMBA9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:P30260-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725924|ensembl:ENSP00000066544	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:p30260-1(display_long)|uniprotkb:CDC27(gene name)|psi-mi:CDC27(display_short)|uniprotkb:ANAPC3(gene name synonym)|uniprotkb:D0S1430E(gene name synonym)|uniprotkb:D17S978E(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 3(gene name synonym)|uniprotkb:CDC27 homolog(gene name synonym)|uniprotkb:H-NUC(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726212|imex:IM-26717-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	ensembl:ENSG00000004897(gene)|ensembl:ENST00000066544(transcript)|uniprotkb:P30260-1(isoform-parent)|intact:EBI-994813(isoform-parent)	-	-	-	figure legend:Extended data figure 1a, Extended data figure 1k|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:YOrJCRal5ZfO7kP2b8FPon0Yytw9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q13042-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-15798699|ensembl:ENSP00000348554|ensembl:ENSP00000353549	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q13042-1(display_long)|uniprotkb:CDC16(gene name)|psi-mi:CDC16(display_short)|uniprotkb:ANAPC6(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 6(gene name synonym)|uniprotkb:CDC16 homolog(gene name synonym)|uniprotkb:Cyclosome subunit 6(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726212|imex:IM-26717-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	ensembl:ENSG00000130177(gene)|ensembl:ENST00000356221(transcript)|ensembl:ENST00000360383(transcript)|intact:EBI-994830(isoform-parent)	-	-	-	figure legend:Extended data figure 1a, Extended data figure 1k|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:AAG0s18JHrn+M5dG7T/N6t0Y97w9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q13257-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20724396|ensembl:ENSP00000296509	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q13257-1(display_long)|uniprotkb:Mitotic arrest deficient 2-like protein 1(gene name synonym)|uniprotkb:MAD2L1(gene name)|psi-mi:MAD2L1(display_short)|uniprotkb:MAD2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726212|imex:IM-26717-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	ensembl:ENSG00000164109(gene)|ensembl:ENST00000296509(transcript)|intact:EBI-78203(isoform-parent)	-	-	-	figure legend:Extended data figure 1a, Extended data figure 1k|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:FyL1tmJllOZ4gQvwWb96aV9PMFw9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX2-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725911	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx2-1(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726212|imex:IM-26717-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX2-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1a, Extended data figure 1k|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX3-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725898	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx3-1(display_long)|uniprotkb:ANAPC7(gene name)|psi-mi:ANAPC7(display_short)|uniprotkb:APC7(gene name synonym)|uniprotkb:Cyclosome subunit 7(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726212|imex:IM-26717-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	intact:EBI-1384164(isoform-parent)	-	-	-	figure legend:Extended data figure 1a, Extended data figure 1k|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:2q+llvuIzK2MOWjPuOUxmyN782E9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX4-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725945	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx4-1(display_long)|uniprotkb:ANAPC5(gene name)|psi-mi:ANAPC5(display_short)|uniprotkb:APC5(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726212|imex:IM-26717-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX4-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1a, Extended data figure 1k|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:Bg/ZL1IEXYdO6XblNQvxjhVX9tI9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX5-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725932	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx5-1(display_long)|uniprotkb:ANAPC4(gene name)|psi-mi:ANAPC4(display_short)|uniprotkb:APC4(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726212|imex:IM-26717-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX5-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1a, Extended data figure 1k|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:c3Z2ioMzMExZK39sLFZCSaAFW9M9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX6-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725938	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx6-1(display_long)|uniprotkb:ANAPC2(gene name)|psi-mi:ANAPC2(display_short)|uniprotkb:APC2(gene name synonym)|uniprotkb:KIAA1406(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726212|imex:IM-26717-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX6-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1a, Extended data figure 1k|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:PVV9qYjevihqygZjLzBflQ0Ob409606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q96DE5	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-2555937|ensembl:ENSP00000299381|ensembl:ENSP00000477760	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:apc16_human(display_long)|uniprotkb:C10orf104(gene name synonym)|uniprotkb:Cyclosome subunit 16(gene name synonym)|uniprotkb:ANAPC16(gene name)|psi-mi:ANAPC16(display_short)|uniprotkb:CENP-27(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726508|imex:IM-26717-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	refseq:NP_001229475.1|refseq:NP_001229476.1|refseq:NP_775744.1|ensembl:ENSG00000166295(gene)|ensembl:ENST00000299381(transcript)|ensembl:ENST00000621663(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0051301"(cell division)|interpro:IPR029641|mint:Q96DE5|rcsb pdb:4RG6|rcsb pdb:4RG9|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|dip:DIP-56449N	-	-	-	figure legend:Extended data figure 1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:THae4cAe47vuWr79Lo0BoGbQY/I9606	rigid:VHAmlMJ3Dz+eZRvGVPe6gEiFg4U	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9H1A4	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-395918|uniprotkb:Q2M3H8|uniprotkb:Q9BSE6|uniprotkb:Q9H8D0|ensembl:ENSP00000339109	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:apc1_human(display_long)|uniprotkb:ANAPC1(gene name)|psi-mi:ANAPC1(display_short)|uniprotkb:TSG24(gene name synonym)|uniprotkb:Cyclosome subunit 1(gene name synonym)|uniprotkb:Testis-specific gene 24 protein(gene name synonym)|uniprotkb:Mitotic checkpoint regulator(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726508|imex:IM-26717-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	refseq:NP_073153.1|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENSG00000153107(gene)|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|ensembl:ENST00000341068(transcript)|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5L9U|go:"GO:0005680"(anaphase-promoting complex)|rcsb pdb:5LCW|go:"GO:0005829"(cytosol)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|rcsb pdb:5LGG|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|interpro:IPR011989(Armadillo-like helical)|interpro:IPR024990|interpro:IPR041221|mint:Q9H1A4|dip:DIP-32940N	-	-	-	figure legend:Extended data figure 1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:GCcoaN+24WplwiaqcHwHsjyWn789606	rigid:VHAmlMJ3Dz+eZRvGVPe6gEiFg4U	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q12834	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-367462|uniprotkb:Q5JUY4|uniprotkb:Q9BW56|uniprotkb:Q9UQI9|uniprotkb:B2R6Z6|uniprotkb:D3DPJ1|ensembl:ENSP00000308450|ensembl:ENSP00000361540	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:cdc20_human(display_long)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:p55CDC(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726508|imex:IM-26717-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	rcsb pdb:6Q6H|reactome:R-HSA-141405|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174048|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176417|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-5689880|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983168|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051301"(cell division)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q12834|rcsb pdb:4GGA|rcsb pdb:4GGC|rcsb pdb:4GGD|rcsb pdb:4N14|rcsb pdb:5G04|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5LCW|rcsb pdb:6F0X|rcsb pdb:6Q6G|refseq:NP_001246.2|ensembl:ENSG00000117399(gene)|ensembl:ENST00000310955(transcript)|ensembl:ENST00000372462(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-29655N	-	-	-	figure legend:Extended data figure 1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:15j9Heovw6LpbClp5kT9Wz6a88A9606	rigid:VHAmlMJ3Dz+eZRvGVPe6gEiFg4U	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q8NHZ8	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-2555941|ensembl:ENSP00000363322	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:cdc26_human(display_long)|uniprotkb:ANAPC12(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 12(gene name synonym)|uniprotkb:C9orf17(gene name synonym)|uniprotkb:Cell division cycle protein 26 homolog(gene name synonym)|uniprotkb:CDC26(gene name)|psi-mi:CDC26(display_short)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726508|imex:IM-26717-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	dip:DIP-48551N|refseq:NP_644815.1|ensembl:ENSG00000176386(gene)|ensembl:ENST00000374206(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR018860|mint:Q8NHZ8|rcsb pdb:3HYM|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-174048|reactome:R-HSA-69017|reactome:R-HSA-174084|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|refseq:XP_016870062.1|refseq:XP_016870063.1|refseq:XP_016870064.1	-	-	-	figure legend:Extended data figure 1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:cEo8S5g8dgb5r54+8FFc8ZFcCB09606	rigid:VHAmlMJ3Dz+eZRvGVPe6gEiFg4U	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:O60566-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725951	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:o60566-1(display_long)|uniprotkb:BUB1B(gene name)|psi-mi:BUB1B(display_short)|uniprotkb:BUBR1(gene name synonym)|uniprotkb:MAD3L(gene name synonym)|uniprotkb:SSK1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726508|imex:IM-26717-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:O60566-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:EgsQ2ZywEJ+r8hd95vcNEyikMBA9606	rigid:VHAmlMJ3Dz+eZRvGVPe6gEiFg4U	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:P30260-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725924|ensembl:ENSP00000066544	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:p30260-1(display_long)|uniprotkb:CDC27(gene name)|psi-mi:CDC27(display_short)|uniprotkb:ANAPC3(gene name synonym)|uniprotkb:D0S1430E(gene name synonym)|uniprotkb:D17S978E(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 3(gene name synonym)|uniprotkb:CDC27 homolog(gene name synonym)|uniprotkb:H-NUC(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726508|imex:IM-26717-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	ensembl:ENSG00000004897(gene)|ensembl:ENST00000066544(transcript)|uniprotkb:P30260-1(isoform-parent)|intact:EBI-994813(isoform-parent)	-	-	-	figure legend:Extended data figure 1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:YOrJCRal5ZfO7kP2b8FPon0Yytw9606	rigid:VHAmlMJ3Dz+eZRvGVPe6gEiFg4U	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:P60006-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725917	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:p60006-1(display_long)|uniprotkb:ANAPC15(gene name)|psi-mi:ANAPC15(display_short)|uniprotkb:C11orf51(gene name synonym)|uniprotkb:HSPC020(orf name)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726508|imex:IM-26717-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:P60006-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:nQTEwP1LHxaqHPJEYm/gr3bCi649606	rigid:VHAmlMJ3Dz+eZRvGVPe6gEiFg4U	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q13042-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-15798699|ensembl:ENSP00000348554|ensembl:ENSP00000353549	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q13042-1(display_long)|uniprotkb:CDC16(gene name)|psi-mi:CDC16(display_short)|uniprotkb:ANAPC6(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 6(gene name synonym)|uniprotkb:CDC16 homolog(gene name synonym)|uniprotkb:Cyclosome subunit 6(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726508|imex:IM-26717-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	ensembl:ENSG00000130177(gene)|ensembl:ENST00000356221(transcript)|ensembl:ENST00000360383(transcript)|intact:EBI-994830(isoform-parent)	-	-	-	figure legend:Extended data figure 1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:AAG0s18JHrn+M5dG7T/N6t0Y97w9606	rigid:VHAmlMJ3Dz+eZRvGVPe6gEiFg4U	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q13257-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20724396|ensembl:ENSP00000296509	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q13257-1(display_long)|uniprotkb:Mitotic arrest deficient 2-like protein 1(gene name synonym)|uniprotkb:MAD2L1(gene name)|psi-mi:MAD2L1(display_short)|uniprotkb:MAD2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726508|imex:IM-26717-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	ensembl:ENSG00000164109(gene)|ensembl:ENST00000296509(transcript)|intact:EBI-78203(isoform-parent)	-	-	-	figure legend:Extended data figure 1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:FyL1tmJllOZ4gQvwWb96aV9PMFw9606	rigid:VHAmlMJ3Dz+eZRvGVPe6gEiFg4U	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX2-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725911	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx2-1(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726508|imex:IM-26717-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX2-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606	rigid:VHAmlMJ3Dz+eZRvGVPe6gEiFg4U	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX3-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725898	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx3-1(display_long)|uniprotkb:ANAPC7(gene name)|psi-mi:ANAPC7(display_short)|uniprotkb:APC7(gene name synonym)|uniprotkb:Cyclosome subunit 7(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726508|imex:IM-26717-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	intact:EBI-1384164(isoform-parent)	-	-	-	figure legend:Extended data figure 1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:2q+llvuIzK2MOWjPuOUxmyN782E9606	rigid:VHAmlMJ3Dz+eZRvGVPe6gEiFg4U	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX4-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725945	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx4-1(display_long)|uniprotkb:ANAPC5(gene name)|psi-mi:ANAPC5(display_short)|uniprotkb:APC5(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726508|imex:IM-26717-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX4-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:Bg/ZL1IEXYdO6XblNQvxjhVX9tI9606	rigid:VHAmlMJ3Dz+eZRvGVPe6gEiFg4U	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX5-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725932	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx5-1(display_long)|uniprotkb:ANAPC4(gene name)|psi-mi:ANAPC4(display_short)|uniprotkb:APC4(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726508|imex:IM-26717-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX5-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:c3Z2ioMzMExZK39sLFZCSaAFW9M9606	rigid:VHAmlMJ3Dz+eZRvGVPe6gEiFg4U	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX6-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725938	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx6-1(display_long)|uniprotkb:ANAPC2(gene name)|psi-mi:ANAPC2(display_short)|uniprotkb:APC2(gene name synonym)|uniprotkb:KIAA1406(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726508|imex:IM-26717-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX6-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:PVV9qYjevihqygZjLzBflQ0Ob409606	rigid:VHAmlMJ3Dz+eZRvGVPe6gEiFg4U	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9H1A4	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-395918|uniprotkb:Q2M3H8|uniprotkb:Q9BSE6|uniprotkb:Q9H8D0|ensembl:ENSP00000339109	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:apc1_human(display_long)|uniprotkb:ANAPC1(gene name)|psi-mi:ANAPC1(display_short)|uniprotkb:TSG24(gene name synonym)|uniprotkb:Cyclosome subunit 1(gene name synonym)|uniprotkb:Testis-specific gene 24 protein(gene name synonym)|uniprotkb:Mitotic checkpoint regulator(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726536|imex:IM-26717-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	refseq:NP_073153.1|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENSG00000153107(gene)|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|ensembl:ENST00000341068(transcript)|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5L9U|go:"GO:0005680"(anaphase-promoting complex)|rcsb pdb:5LCW|go:"GO:0005829"(cytosol)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|rcsb pdb:5LGG|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|interpro:IPR011989(Armadillo-like helical)|interpro:IPR024990|interpro:IPR041221|mint:Q9H1A4|dip:DIP-32940N	-	-	-	figure legend:Extended data figure 1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:GCcoaN+24WplwiaqcHwHsjyWn789606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q12834	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-367462|uniprotkb:Q5JUY4|uniprotkb:Q9BW56|uniprotkb:Q9UQI9|uniprotkb:B2R6Z6|uniprotkb:D3DPJ1|ensembl:ENSP00000308450|ensembl:ENSP00000361540	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:cdc20_human(display_long)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:p55CDC(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726536|imex:IM-26717-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	rcsb pdb:6Q6H|reactome:R-HSA-141405|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174048|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176417|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-5689880|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983168|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051301"(cell division)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q12834|rcsb pdb:4GGA|rcsb pdb:4GGC|rcsb pdb:4GGD|rcsb pdb:4N14|rcsb pdb:5G04|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5LCW|rcsb pdb:6F0X|rcsb pdb:6Q6G|refseq:NP_001246.2|ensembl:ENSG00000117399(gene)|ensembl:ENST00000310955(transcript)|ensembl:ENST00000372462(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-29655N	-	-	-	figure legend:Extended data figure 1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:15j9Heovw6LpbClp5kT9Wz6a88A9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:O60566-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725951	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:o60566-1(display_long)|uniprotkb:BUB1B(gene name)|psi-mi:BUB1B(display_short)|uniprotkb:BUBR1(gene name synonym)|uniprotkb:MAD3L(gene name synonym)|uniprotkb:SSK1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726536|imex:IM-26717-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:O60566-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:EgsQ2ZywEJ+r8hd95vcNEyikMBA9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:P30260-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725924|ensembl:ENSP00000066544	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:p30260-1(display_long)|uniprotkb:CDC27(gene name)|psi-mi:CDC27(display_short)|uniprotkb:ANAPC3(gene name synonym)|uniprotkb:D0S1430E(gene name synonym)|uniprotkb:D17S978E(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 3(gene name synonym)|uniprotkb:CDC27 homolog(gene name synonym)|uniprotkb:H-NUC(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726536|imex:IM-26717-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	ensembl:ENSG00000004897(gene)|ensembl:ENST00000066544(transcript)|uniprotkb:P30260-1(isoform-parent)|intact:EBI-994813(isoform-parent)	-	-	-	figure legend:Extended data figure 1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:YOrJCRal5ZfO7kP2b8FPon0Yytw9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q13042-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-15798699|ensembl:ENSP00000348554|ensembl:ENSP00000353549	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q13042-1(display_long)|uniprotkb:CDC16(gene name)|psi-mi:CDC16(display_short)|uniprotkb:ANAPC6(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 6(gene name synonym)|uniprotkb:CDC16 homolog(gene name synonym)|uniprotkb:Cyclosome subunit 6(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726536|imex:IM-26717-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	ensembl:ENSG00000130177(gene)|ensembl:ENST00000356221(transcript)|ensembl:ENST00000360383(transcript)|intact:EBI-994830(isoform-parent)	-	-	-	figure legend:Extended data figure 1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:AAG0s18JHrn+M5dG7T/N6t0Y97w9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q13257-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20724396|ensembl:ENSP00000296509	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q13257-1(display_long)|uniprotkb:Mitotic arrest deficient 2-like protein 1(gene name synonym)|uniprotkb:MAD2L1(gene name)|psi-mi:MAD2L1(display_short)|uniprotkb:MAD2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726536|imex:IM-26717-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	ensembl:ENSG00000164109(gene)|ensembl:ENST00000296509(transcript)|intact:EBI-78203(isoform-parent)	-	-	-	figure legend:Extended data figure 1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:FyL1tmJllOZ4gQvwWb96aV9PMFw9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX2-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725911	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx2-1(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726536|imex:IM-26717-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX2-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX3-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725898	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx3-1(display_long)|uniprotkb:ANAPC7(gene name)|psi-mi:ANAPC7(display_short)|uniprotkb:APC7(gene name synonym)|uniprotkb:Cyclosome subunit 7(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726536|imex:IM-26717-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	intact:EBI-1384164(isoform-parent)	-	-	-	figure legend:Extended data figure 1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:2q+llvuIzK2MOWjPuOUxmyN782E9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX4-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725945	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx4-1(display_long)|uniprotkb:ANAPC5(gene name)|psi-mi:ANAPC5(display_short)|uniprotkb:APC5(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726536|imex:IM-26717-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX4-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:Bg/ZL1IEXYdO6XblNQvxjhVX9tI9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX5-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725932	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx5-1(display_long)|uniprotkb:ANAPC4(gene name)|psi-mi:ANAPC4(display_short)|uniprotkb:APC4(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726536|imex:IM-26717-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX5-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:c3Z2ioMzMExZK39sLFZCSaAFW9M9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX6-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725938	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx6-1(display_long)|uniprotkb:ANAPC2(gene name)|psi-mi:ANAPC2(display_short)|uniprotkb:APC2(gene name synonym)|uniprotkb:KIAA1406(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726536|imex:IM-26717-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX6-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:PVV9qYjevihqygZjLzBflQ0Ob409606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9H1A4	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-395918|uniprotkb:Q2M3H8|uniprotkb:Q9BSE6|uniprotkb:Q9H8D0|ensembl:ENSP00000339109	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:apc1_human(display_long)|uniprotkb:ANAPC1(gene name)|psi-mi:ANAPC1(display_short)|uniprotkb:TSG24(gene name synonym)|uniprotkb:Cyclosome subunit 1(gene name synonym)|uniprotkb:Testis-specific gene 24 protein(gene name synonym)|uniprotkb:Mitotic checkpoint regulator(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726550|imex:IM-26717-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	refseq:NP_073153.1|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENSG00000153107(gene)|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|ensembl:ENST00000341068(transcript)|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5L9U|go:"GO:0005680"(anaphase-promoting complex)|rcsb pdb:5LCW|go:"GO:0005829"(cytosol)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|rcsb pdb:5LGG|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|interpro:IPR011989(Armadillo-like helical)|interpro:IPR024990|interpro:IPR041221|mint:Q9H1A4|dip:DIP-32940N	-	-	-	figure legend:Extended data figure 1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:GCcoaN+24WplwiaqcHwHsjyWn789606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q12834	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-367462|uniprotkb:Q5JUY4|uniprotkb:Q9BW56|uniprotkb:Q9UQI9|uniprotkb:B2R6Z6|uniprotkb:D3DPJ1|ensembl:ENSP00000308450|ensembl:ENSP00000361540	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:cdc20_human(display_long)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:p55CDC(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726550|imex:IM-26717-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	rcsb pdb:6Q6H|reactome:R-HSA-141405|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174048|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176417|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-5689880|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983168|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051301"(cell division)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q12834|rcsb pdb:4GGA|rcsb pdb:4GGC|rcsb pdb:4GGD|rcsb pdb:4N14|rcsb pdb:5G04|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5LCW|rcsb pdb:6F0X|rcsb pdb:6Q6G|refseq:NP_001246.2|ensembl:ENSG00000117399(gene)|ensembl:ENST00000310955(transcript)|ensembl:ENST00000372462(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-29655N	-	-	-	figure legend:Extended data figure 1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:15j9Heovw6LpbClp5kT9Wz6a88A9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UM13	uniprotkb:O60566-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725951	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:o60566-1(display_long)|uniprotkb:BUB1B(gene name)|psi-mi:BUB1B(display_short)|uniprotkb:BUBR1(gene name synonym)|uniprotkb:MAD3L(gene name synonym)|uniprotkb:SSK1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726550|imex:IM-26717-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:O60566-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:EgsQ2ZywEJ+r8hd95vcNEyikMBA9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UM13	uniprotkb:P30260-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725924|ensembl:ENSP00000066544	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:p30260-1(display_long)|uniprotkb:CDC27(gene name)|psi-mi:CDC27(display_short)|uniprotkb:ANAPC3(gene name synonym)|uniprotkb:D0S1430E(gene name synonym)|uniprotkb:D17S978E(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 3(gene name synonym)|uniprotkb:CDC27 homolog(gene name synonym)|uniprotkb:H-NUC(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726550|imex:IM-26717-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	ensembl:ENSG00000004897(gene)|ensembl:ENST00000066544(transcript)|uniprotkb:P30260-1(isoform-parent)|intact:EBI-994813(isoform-parent)	-	-	-	figure legend:Extended data figure 1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:YOrJCRal5ZfO7kP2b8FPon0Yytw9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q13042-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-15798699|ensembl:ENSP00000348554|ensembl:ENSP00000353549	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q13042-1(display_long)|uniprotkb:CDC16(gene name)|psi-mi:CDC16(display_short)|uniprotkb:ANAPC6(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 6(gene name synonym)|uniprotkb:CDC16 homolog(gene name synonym)|uniprotkb:Cyclosome subunit 6(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726550|imex:IM-26717-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	ensembl:ENSG00000130177(gene)|ensembl:ENST00000356221(transcript)|ensembl:ENST00000360383(transcript)|intact:EBI-994830(isoform-parent)	-	-	-	figure legend:Extended data figure 1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:AAG0s18JHrn+M5dG7T/N6t0Y97w9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UM13	uniprotkb:Q13257-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20724396|ensembl:ENSP00000296509	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q13257-1(display_long)|uniprotkb:Mitotic arrest deficient 2-like protein 1(gene name synonym)|uniprotkb:MAD2L1(gene name)|psi-mi:MAD2L1(display_short)|uniprotkb:MAD2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726550|imex:IM-26717-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	ensembl:ENSG00000164109(gene)|ensembl:ENST00000296509(transcript)|intact:EBI-78203(isoform-parent)	-	-	-	figure legend:Extended data figure 1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:FyL1tmJllOZ4gQvwWb96aV9PMFw9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UM13	uniprotkb:Q9UJX2-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725911	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx2-1(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726550|imex:IM-26717-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX2-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX3-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725898	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx3-1(display_long)|uniprotkb:ANAPC7(gene name)|psi-mi:ANAPC7(display_short)|uniprotkb:APC7(gene name synonym)|uniprotkb:Cyclosome subunit 7(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726550|imex:IM-26717-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	intact:EBI-1384164(isoform-parent)	-	-	-	figure legend:Extended data figure 1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:2q+llvuIzK2MOWjPuOUxmyN782E9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX4-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725945	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx4-1(display_long)|uniprotkb:ANAPC5(gene name)|psi-mi:ANAPC5(display_short)|uniprotkb:APC5(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726550|imex:IM-26717-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX4-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:Bg/ZL1IEXYdO6XblNQvxjhVX9tI9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX5-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725932	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx5-1(display_long)|uniprotkb:ANAPC4(gene name)|psi-mi:ANAPC4(display_short)|uniprotkb:APC4(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726550|imex:IM-26717-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX5-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:c3Z2ioMzMExZK39sLFZCSaAFW9M9606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX6-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725938	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx6-1(display_long)|uniprotkb:ANAPC2(gene name)|psi-mi:ANAPC2(display_short)|uniprotkb:APC2(gene name synonym)|uniprotkb:KIAA1406(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726550|imex:IM-26717-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX6-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/04	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:PVV9qYjevihqygZjLzBflQ0Ob409606	rigid:R+A5CP5+4dHu0Pv05zYpH7pPovE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9H1A4	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-395918|uniprotkb:Q2M3H8|uniprotkb:Q9BSE6|uniprotkb:Q9H8D0|ensembl:ENSP00000339109	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:apc1_human(display_long)|uniprotkb:ANAPC1(gene name)|psi-mi:ANAPC1(display_short)|uniprotkb:TSG24(gene name synonym)|uniprotkb:Cyclosome subunit 1(gene name synonym)|uniprotkb:Testis-specific gene 24 protein(gene name synonym)|uniprotkb:Mitotic checkpoint regulator(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726564|imex:IM-26717-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	refseq:NP_073153.1|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENSG00000153107(gene)|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|ensembl:ENST00000341068(transcript)|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5L9U|go:"GO:0005680"(anaphase-promoting complex)|rcsb pdb:5LCW|go:"GO:0005829"(cytosol)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|rcsb pdb:5LGG|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|interpro:IPR011989(Armadillo-like helical)|interpro:IPR024990|interpro:IPR041221|mint:Q9H1A4|dip:DIP-32940N	-	-	-	figure legend:Extended data figure 1e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/07	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:GCcoaN+24WplwiaqcHwHsjyWn789606	rigid:jyFqzomlebbPPHcQC/YOjagYFZE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q12834	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-367462|uniprotkb:Q5JUY4|uniprotkb:Q9BW56|uniprotkb:Q9UQI9|uniprotkb:B2R6Z6|uniprotkb:D3DPJ1|ensembl:ENSP00000308450|ensembl:ENSP00000361540	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:cdc20_human(display_long)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:p55CDC(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726564|imex:IM-26717-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	rcsb pdb:6Q6H|reactome:R-HSA-141405|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174048|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176417|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-5689880|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983168|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051301"(cell division)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q12834|rcsb pdb:4GGA|rcsb pdb:4GGC|rcsb pdb:4GGD|rcsb pdb:4N14|rcsb pdb:5G04|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5LCW|rcsb pdb:6F0X|rcsb pdb:6Q6G|refseq:NP_001246.2|ensembl:ENSG00000117399(gene)|ensembl:ENST00000310955(transcript)|ensembl:ENST00000372462(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-29655N	-	-	-	figure legend:Extended data figure 1e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/07	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:15j9Heovw6LpbClp5kT9Wz6a88A9606	rigid:jyFqzomlebbPPHcQC/YOjagYFZE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:O60566-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725951	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:o60566-1(display_long)|uniprotkb:BUB1B(gene name)|psi-mi:BUB1B(display_short)|uniprotkb:BUBR1(gene name synonym)|uniprotkb:MAD3L(gene name synonym)|uniprotkb:SSK1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726564|imex:IM-26717-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:O60566-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/07	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:EgsQ2ZywEJ+r8hd95vcNEyikMBA9606	rigid:jyFqzomlebbPPHcQC/YOjagYFZE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:P30260-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725924|ensembl:ENSP00000066544	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:p30260-1(display_long)|uniprotkb:CDC27(gene name)|psi-mi:CDC27(display_short)|uniprotkb:ANAPC3(gene name synonym)|uniprotkb:D0S1430E(gene name synonym)|uniprotkb:D17S978E(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 3(gene name synonym)|uniprotkb:CDC27 homolog(gene name synonym)|uniprotkb:H-NUC(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726564|imex:IM-26717-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	ensembl:ENSG00000004897(gene)|ensembl:ENST00000066544(transcript)|uniprotkb:P30260-1(isoform-parent)|intact:EBI-994813(isoform-parent)	-	-	-	figure legend:Extended data figure 1e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/07	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:YOrJCRal5ZfO7kP2b8FPon0Yytw9606	rigid:jyFqzomlebbPPHcQC/YOjagYFZE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:P60006-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725917	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:p60006-1(display_long)|uniprotkb:ANAPC15(gene name)|psi-mi:ANAPC15(display_short)|uniprotkb:C11orf51(gene name synonym)|uniprotkb:HSPC020(orf name)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726564|imex:IM-26717-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:P60006-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/07	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:nQTEwP1LHxaqHPJEYm/gr3bCi649606	rigid:jyFqzomlebbPPHcQC/YOjagYFZE	false	-	strep ii tag:c-c|mutation:23-57	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9UM13	uniprotkb:Q13042-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-15798699|ensembl:ENSP00000348554|ensembl:ENSP00000353549	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q13042-1(display_long)|uniprotkb:CDC16(gene name)|psi-mi:CDC16(display_short)|uniprotkb:ANAPC6(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 6(gene name synonym)|uniprotkb:CDC16 homolog(gene name synonym)|uniprotkb:Cyclosome subunit 6(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726564|imex:IM-26717-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	ensembl:ENSG00000130177(gene)|ensembl:ENST00000356221(transcript)|ensembl:ENST00000360383(transcript)|intact:EBI-994830(isoform-parent)	-	-	-	figure legend:Extended data figure 1e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/07	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:AAG0s18JHrn+M5dG7T/N6t0Y97w9606	rigid:jyFqzomlebbPPHcQC/YOjagYFZE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q13257-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20724396|ensembl:ENSP00000296509	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q13257-1(display_long)|uniprotkb:Mitotic arrest deficient 2-like protein 1(gene name synonym)|uniprotkb:MAD2L1(gene name)|psi-mi:MAD2L1(display_short)|uniprotkb:MAD2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726564|imex:IM-26717-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	ensembl:ENSG00000164109(gene)|ensembl:ENST00000296509(transcript)|intact:EBI-78203(isoform-parent)	-	-	-	figure legend:Extended data figure 1e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/07	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:FyL1tmJllOZ4gQvwWb96aV9PMFw9606	rigid:jyFqzomlebbPPHcQC/YOjagYFZE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX2-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725911	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx2-1(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726564|imex:IM-26717-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX2-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/07	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606	rigid:jyFqzomlebbPPHcQC/YOjagYFZE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX3-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725898	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx3-1(display_long)|uniprotkb:ANAPC7(gene name)|psi-mi:ANAPC7(display_short)|uniprotkb:APC7(gene name synonym)|uniprotkb:Cyclosome subunit 7(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726564|imex:IM-26717-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	intact:EBI-1384164(isoform-parent)	-	-	-	figure legend:Extended data figure 1e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/07	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:2q+llvuIzK2MOWjPuOUxmyN782E9606	rigid:jyFqzomlebbPPHcQC/YOjagYFZE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX4-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725945	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx4-1(display_long)|uniprotkb:ANAPC5(gene name)|psi-mi:ANAPC5(display_short)|uniprotkb:APC5(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726564|imex:IM-26717-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX4-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/07	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:Bg/ZL1IEXYdO6XblNQvxjhVX9tI9606	rigid:jyFqzomlebbPPHcQC/YOjagYFZE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX5-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725932	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx5-1(display_long)|uniprotkb:ANAPC4(gene name)|psi-mi:ANAPC4(display_short)|uniprotkb:APC4(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726564|imex:IM-26717-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX5-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/07	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:c3Z2ioMzMExZK39sLFZCSaAFW9M9606	rigid:jyFqzomlebbPPHcQC/YOjagYFZE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UM13	uniprotkb:Q9UJX6-1	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071|ensembl:ENSP00000403891|ensembl:ENSP00000423995|ensembl:ENSP00000478501	intact:EBI-20725938	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q9ujx6-1(display_long)|uniprotkb:ANAPC2(gene name)|psi-mi:ANAPC2(display_short)|uniprotkb:APC2(gene name synonym)|uniprotkb:KIAA1406(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Alfieri et al. (2016)	imex:IM-26717|pubmed:27509861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20726564|imex:IM-26717-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055700.2|refseq:NP_001305296.1|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|refseq:XP_011529826.1|dip:DIP-39885N|ensembl:ENSG00000164162(gene)|ensembl:ENST00000309439(transcript)|ensembl:ENST00000451299(transcript)|ensembl:ENST00000507656(transcript)|ensembl:ENST00000613466(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|rcsb pdb:6TLJ	uniprotkb:Q9UJX6-1(isoform-parent)	-	-	-	figure legend:Extended data figure 1e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/30	2018/09/07	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:PVV9qYjevihqygZjLzBflQ0Ob409606	rigid:jyFqzomlebbPPHcQC/YOjagYFZE	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)