#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P11308 intact:EBI-16763597 intact:EBI-79704|uniprotkb:B4DTW5|uniprotkb:B4E0T4|ensembl:ENSP00000288319|uniprotkb:Q16113|uniprotkb:Q6XXX4|uniprotkb:Q6XXX5|uniprotkb:Q8IXK9 - psi-mi:erg_human(display_long)|uniprotkb:ERG(gene name)|psi-mi:ERG(display_short)|uniprotkb:Transforming protein ERG(gene name synonym) psi-mi:yap1_human_ets-site1/2(display_short)|psi-mi:EBI-16763597(display_long) psi-mi:"MI:0412"(electrophoretic mobility supershift assay) Kim et al. (2016) imex:IM-26296|pubmed:27109047 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16763576|imex:IM-26296-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0319"(deoxyribonucleic acid) ensembl:ENSG00000157554(gene)|ensembl:ENST00000288319(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1SXE|rcsb pdb:4IRG|rcsb pdb:4IRH|rcsb pdb:4IRI|rcsb pdb:5YBC|rcsb pdb:5YBD|rcsb pdb:6VGE|rcsb pdb:6VGG|refseq:NP_001129626.1|refseq:NP_001129627.1|refseq:NP_001230357.1|refseq:NP_001230358.1|refseq:NP_001230361.1|refseq:NP_004440.1|refseq:NP_891548.1|refseq:NP_001278320.1|dip:DIP-31028N ensembl:ENSG00000137693(see-also) - - - figure legend:Fig. 2 C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/02/09 2020/08/14 rogid:KJaYRzb5lsoL3V19T4l6qjjJfU09606 - - false myc tag:c-c mutation decreasing interaction strength:11-11|mutation decreasing interaction strength:18-18|32p radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:P11308 intact:EBI-16763631 intact:EBI-79704|uniprotkb:B4DTW5|uniprotkb:B4E0T4|ensembl:ENSP00000288319|uniprotkb:Q16113|uniprotkb:Q6XXX4|uniprotkb:Q6XXX5|uniprotkb:Q8IXK9 - psi-mi:erg_human(display_long)|uniprotkb:ERG(gene name)|psi-mi:ERG(display_short)|uniprotkb:Transforming protein ERG(gene name synonym) psi-mi:yap1_human_ets-site6/7_dna-probe(display_short)|psi-mi:EBI-16763631(display_long) psi-mi:"MI:0412"(electrophoretic mobility supershift assay) Kim et al. (2016) imex:IM-26296|pubmed:27109047 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16763620|imex:IM-26296-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0319"(deoxyribonucleic acid) ensembl:ENSG00000157554(gene)|ensembl:ENST00000288319(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1SXE|rcsb pdb:4IRG|rcsb pdb:4IRH|rcsb pdb:4IRI|rcsb pdb:5YBC|rcsb pdb:5YBD|rcsb pdb:6VGE|rcsb pdb:6VGG|refseq:NP_001129626.1|refseq:NP_001129627.1|refseq:NP_001230357.1|refseq:NP_001230358.1|refseq:NP_001230361.1|refseq:NP_004440.1|refseq:NP_891548.1|refseq:NP_001278320.1|dip:DIP-31028N ensembl:ENSG00000137693(see-also) - - - figure legend:Fig. 2 C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/02/09 2020/08/14 rogid:KJaYRzb5lsoL3V19T4l6qjjJfU09606 - - false myc tag:c-c 32p radiolabel:?-?|mutation disrupting interaction strength:8-8|mutation decreasing interaction strength:15-15 - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-16763631 intact:EBI-16763617 - - psi-mi:yap1_human_ets-site6/7_dna-probe(display_short)|psi-mi:EBI-16763631(display_long) psi-mi:e74_dna-probe(display_short)|psi-mi:EBI-16763617(display_long) psi-mi:"MI:0412"(electrophoretic mobility supershift assay) Kim et al. (2016) imex:IM-26296|pubmed:27109047 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:-1(in vitro)|taxid:-1(In vitro) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16763634|imex:IM-26296-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0319"(deoxyribonucleic acid) ensembl:ENSG00000137693(see-also) - - - - figure legend:Fig. 2 D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/02/09 2020/08/14 - - - false 32p radiolabel:?-? mutation disrupting interaction strength:22-23 - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-16763631 uniprotkb:P11308 - intact:EBI-79704|uniprotkb:B4DTW5|uniprotkb:B4E0T4|ensembl:ENSP00000288319|uniprotkb:Q16113|uniprotkb:Q6XXX4|uniprotkb:Q6XXX5|uniprotkb:Q8IXK9 psi-mi:yap1_human_ets-site6/7_dna-probe(display_short)|psi-mi:EBI-16763631(display_long) psi-mi:erg_human(display_long)|uniprotkb:ERG(gene name)|psi-mi:ERG(display_short)|uniprotkb:Transforming protein ERG(gene name synonym) psi-mi:"MI:0412"(electrophoretic mobility supershift assay) Kim et al. (2016) imex:IM-26296|pubmed:27109047 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16763634|imex:IM-26296-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000137693(see-also) ensembl:ENSG00000157554(gene)|ensembl:ENST00000288319(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1SXE|rcsb pdb:4IRG|rcsb pdb:4IRH|rcsb pdb:4IRI|rcsb pdb:5YBC|rcsb pdb:5YBD|rcsb pdb:6VGE|rcsb pdb:6VGG|refseq:NP_001129626.1|refseq:NP_001129627.1|refseq:NP_001230357.1|refseq:NP_001230358.1|refseq:NP_001230361.1|refseq:NP_004440.1|refseq:NP_891548.1|refseq:NP_001278320.1|dip:DIP-31028N - - - figure legend:Fig. 2 D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/02/09 2020/08/14 - rogid:KJaYRzb5lsoL3V19T4l6qjjJfU09606 - false 32p radiolabel:?-? myc tag:c-c - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-16763617 uniprotkb:P11308 - intact:EBI-79704|uniprotkb:B4DTW5|uniprotkb:B4E0T4|ensembl:ENSP00000288319|uniprotkb:Q16113|uniprotkb:Q6XXX4|uniprotkb:Q6XXX5|uniprotkb:Q8IXK9 psi-mi:e74_dna-probe(display_short)|psi-mi:EBI-16763617(display_long) psi-mi:erg_human(display_long)|uniprotkb:ERG(gene name)|psi-mi:ERG(display_short)|uniprotkb:Transforming protein ERG(gene name synonym) psi-mi:"MI:0412"(electrophoretic mobility supershift assay) Kim et al. (2016) imex:IM-26296|pubmed:27109047 taxid:-1(in vitro)|taxid:-1(In vitro) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16764647|imex:IM-26296-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000157554(gene)|ensembl:ENST00000288319(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1SXE|rcsb pdb:4IRG|rcsb pdb:4IRH|rcsb pdb:4IRI|rcsb pdb:5YBC|rcsb pdb:5YBD|rcsb pdb:6VGE|rcsb pdb:6VGG|refseq:NP_001129626.1|refseq:NP_001129627.1|refseq:NP_001230357.1|refseq:NP_001230358.1|refseq:NP_001230361.1|refseq:NP_004440.1|refseq:NP_891548.1|refseq:NP_001278320.1|dip:DIP-31028N - - - figure legend:Fig. 2 C/D|comment:positive control|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/02/09 2020/08/14 - rogid:KJaYRzb5lsoL3V19T4l6qjjJfU09606 - false 32p radiolabel:?-? myc tag:c-c - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-16763597 intact:EBI-16763617 - - psi-mi:yap1_human_ets-site1/2(display_short)|psi-mi:EBI-16763597(display_long) psi-mi:e74_dna-probe(display_short)|psi-mi:EBI-16763617(display_long) psi-mi:"MI:0412"(electrophoretic mobility supershift assay) Kim et al. (2016) imex:IM-26296|pubmed:27109047 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:-1(in vitro)|taxid:-1(In vitro) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16764659|imex:IM-26296-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0319"(deoxyribonucleic acid) ensembl:ENSG00000137693(see-also) - - - - figure legend:Fig. 2 D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/02/09 2020/08/14 - - - false 32p radiolabel:?-? mutation disrupting interaction strength:22-23 - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-16763597 uniprotkb:P11308 - intact:EBI-79704|uniprotkb:B4DTW5|uniprotkb:B4E0T4|ensembl:ENSP00000288319|uniprotkb:Q16113|uniprotkb:Q6XXX4|uniprotkb:Q6XXX5|uniprotkb:Q8IXK9 psi-mi:yap1_human_ets-site1/2(display_short)|psi-mi:EBI-16763597(display_long) psi-mi:erg_human(display_long)|uniprotkb:ERG(gene name)|psi-mi:ERG(display_short)|uniprotkb:Transforming protein ERG(gene name synonym) psi-mi:"MI:0412"(electrophoretic mobility supershift assay) Kim et al. (2016) imex:IM-26296|pubmed:27109047 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16764659|imex:IM-26296-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000137693(see-also) ensembl:ENSG00000157554(gene)|ensembl:ENST00000288319(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1SXE|rcsb pdb:4IRG|rcsb pdb:4IRH|rcsb pdb:4IRI|rcsb pdb:5YBC|rcsb pdb:5YBD|rcsb pdb:6VGE|rcsb pdb:6VGG|refseq:NP_001129626.1|refseq:NP_001129627.1|refseq:NP_001230357.1|refseq:NP_001230358.1|refseq:NP_001230361.1|refseq:NP_004440.1|refseq:NP_891548.1|refseq:NP_001278320.1|dip:DIP-31028N - - - figure legend:Fig. 2 D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/02/09 2020/08/14 - rogid:KJaYRzb5lsoL3V19T4l6qjjJfU09606 - false 32p radiolabel:?-? myc tag:c-c - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-16763617 intact:EBI-16763617 - - psi-mi:e74_dna-probe(display_short)|psi-mi:EBI-16763617(display_long) psi-mi:e74_dna-probe(display_short)|psi-mi:EBI-16763617(display_long) psi-mi:"MI:0412"(electrophoretic mobility supershift assay) Kim et al. (2016) imex:IM-26296|pubmed:27109047 taxid:-1(in vitro)|taxid:-1(In vitro) taxid:-1(in vitro)|taxid:-1(In vitro) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16764673|imex:IM-26296-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0319"(deoxyribonucleic acid) - - - - - figure legend:Fig. 2 D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/02/09 2020/08/14 - - - false 32p radiolabel:?-? mutation disrupting interaction strength:22-23 - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-16763617 uniprotkb:P11308 - intact:EBI-79704|uniprotkb:B4DTW5|uniprotkb:B4E0T4|ensembl:ENSP00000288319|uniprotkb:Q16113|uniprotkb:Q6XXX4|uniprotkb:Q6XXX5|uniprotkb:Q8IXK9 psi-mi:e74_dna-probe(display_short)|psi-mi:EBI-16763617(display_long) psi-mi:erg_human(display_long)|uniprotkb:ERG(gene name)|psi-mi:ERG(display_short)|uniprotkb:Transforming protein ERG(gene name synonym) psi-mi:"MI:0412"(electrophoretic mobility supershift assay) Kim et al. (2016) imex:IM-26296|pubmed:27109047 taxid:-1(in vitro)|taxid:-1(In vitro) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16764673|imex:IM-26296-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000157554(gene)|ensembl:ENST00000288319(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1SXE|rcsb pdb:4IRG|rcsb pdb:4IRH|rcsb pdb:4IRI|rcsb pdb:5YBC|rcsb pdb:5YBD|rcsb pdb:6VGE|rcsb pdb:6VGG|refseq:NP_001129626.1|refseq:NP_001129627.1|refseq:NP_001230357.1|refseq:NP_001230358.1|refseq:NP_001230361.1|refseq:NP_004440.1|refseq:NP_891548.1|refseq:NP_001278320.1|dip:DIP-31028N - - - figure legend:Fig. 2 D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/02/09 2020/08/14 - rogid:KJaYRzb5lsoL3V19T4l6qjjJfU09606 - false 32p radiolabel:?-? myc tag:c-c - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:O75164 uniprotkb:P11308 intact:EBI-936709|uniprotkb:Q5VVB1|ensembl:ENSP00000361473 intact:EBI-79704|uniprotkb:B4DTW5|uniprotkb:B4E0T4|ensembl:ENSP00000288319|uniprotkb:Q16113|uniprotkb:Q6XXX4|uniprotkb:Q6XXX5|uniprotkb:Q8IXK9 psi-mi:kdm4a_human(display_long)|uniprotkb:KDM4A(gene name)|psi-mi:KDM4A(display_short)|uniprotkb:JMJD2(gene name synonym)|uniprotkb:KIAA0677(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2A(gene name synonym)|uniprotkb:JHDM3A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(36) demethylase 4A"(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4A"(gene name synonym)|uniprotkb:JMJD2A(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3A(gene name synonym) psi-mi:erg_human(display_long)|uniprotkb:ERG(gene name)|psi-mi:ERG(display_short)|uniprotkb:Transforming protein ERG(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kim et al. (2016) imex:IM-26296|pubmed:27109047 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16763658|imex:IM-26296-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055478.2|refseq:XP_005271411.1|refseq:XP_005271412.1|dip:DIP-29372N|ensembl:ENSG00000066135(gene)|ensembl:ENST00000372396(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016577"(histone demethylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:O75164|rcsb pdb:2GF7|rcsb pdb:2GFA|rcsb pdb:2GP3|rcsb pdb:2GP5|rcsb pdb:2OQ6|rcsb pdb:2OQ7|rcsb pdb:2OS2|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2P5B|rcsb pdb:2PXJ|rcsb pdb:2Q8C|rcsb pdb:2Q8D|rcsb pdb:2Q8E|rcsb pdb:2QQR|rcsb pdb:2QQS|rcsb pdb:2VD7|rcsb pdb:2WWJ|rcsb pdb:2YBK|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3NJY|rcsb pdb:3PDQ|rcsb pdb:3RVH|rcsb pdb:3U4S|rcsb pdb:4AI9|rcsb pdb:4BIS|rcsb pdb:4GD4|rcsb pdb:4URA|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:5A7N|rcsb pdb:5A7O|rcsb pdb:5A7P|rcsb pdb:5A7Q|rcsb pdb:5A7S|rcsb pdb:5A7W|rcsb pdb:5A80|rcsb pdb:5ANQ|rcsb pdb:5D6W|rcsb pdb:5D6X|rcsb pdb:5D6Y|rcsb pdb:5F2S|rcsb pdb:5F2W|rcsb pdb:5F32|rcsb pdb:5F37|rcsb pdb:5F39|rcsb pdb:5F3C|rcsb pdb:5F3E|rcsb pdb:5F3G|rcsb pdb:5F3I|rcsb pdb:5F5I|rcsb pdb:5FPV|rcsb pdb:5FWE|rcsb pdb:5FY8|rcsb pdb:5FYC|rcsb pdb:5FYH|rcsb pdb:5FYI|rcsb pdb:5LY1|rcsb pdb:5LY2|rcsb pdb:5TVR|rcsb pdb:5TVS|rcsb pdb:5VAR|rcsb pdb:5VGI|rcsb pdb:5VMP|rcsb pdb:6CG1|rcsb pdb:6CG2|rcsb pdb:6G5W|rcsb pdb:6G5X|rcsb pdb:6H4O|rcsb pdb:6H4P|rcsb pdb:6H4Q|rcsb pdb:6H4R|rcsb pdb:6H4S|rcsb pdb:6H4T|rcsb pdb:6H4U|rcsb pdb:6H4V|rcsb pdb:6H4W|rcsb pdb:6H4X|rcsb pdb:6H4Y|rcsb pdb:6H8P|rcsb pdb:6HGT|rcsb pdb:7D4A|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9029569 ensembl:ENSG00000157554(gene)|ensembl:ENST00000288319(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1SXE|rcsb pdb:4IRG|rcsb pdb:4IRH|rcsb pdb:4IRI|rcsb pdb:5YBC|rcsb pdb:5YBD|rcsb pdb:6VGE|rcsb pdb:6VGG|refseq:NP_001129626.1|refseq:NP_001129627.1|refseq:NP_001230357.1|refseq:NP_001230358.1|refseq:NP_001230361.1|refseq:NP_004440.1|refseq:NP_891548.1|refseq:NP_001278320.1|dip:DIP-31028N - - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2018/02/09 2020/08/14 rogid:P8atv/4zKIc7bVg3IZYlw5gVIHY9606 rogid:KJaYRzb5lsoL3V19T4l6qjjJfU09606 rigid:JXpqaj9J4zBWsFoMM6VAfmOEhJc false ha tag:?-? myc tag:c-c|flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O75164 uniprotkb:P11308 intact:EBI-936709|uniprotkb:Q5VVB1|ensembl:ENSP00000361473 intact:EBI-79704|uniprotkb:B4DTW5|uniprotkb:B4E0T4|ensembl:ENSP00000288319|uniprotkb:Q16113|uniprotkb:Q6XXX4|uniprotkb:Q6XXX5|uniprotkb:Q8IXK9 psi-mi:kdm4a_human(display_long)|uniprotkb:KDM4A(gene name)|psi-mi:KDM4A(display_short)|uniprotkb:JMJD2(gene name synonym)|uniprotkb:KIAA0677(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2A(gene name synonym)|uniprotkb:JHDM3A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(36) demethylase 4A"(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4A"(gene name synonym)|uniprotkb:JMJD2A(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3A(gene name synonym) psi-mi:erg_human(display_long)|uniprotkb:ERG(gene name)|psi-mi:ERG(display_short)|uniprotkb:Transforming protein ERG(gene name synonym) psi-mi:"MI:0096"(pull down) Kim et al. (2016) imex:IM-26296|pubmed:27109047 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16763680|imex:IM-26296-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055478.2|refseq:XP_005271411.1|refseq:XP_005271412.1|dip:DIP-29372N|ensembl:ENSG00000066135(gene)|ensembl:ENST00000372396(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016577"(histone demethylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:O75164|rcsb pdb:2GF7|rcsb pdb:2GFA|rcsb pdb:2GP3|rcsb pdb:2GP5|rcsb pdb:2OQ6|rcsb pdb:2OQ7|rcsb pdb:2OS2|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2P5B|rcsb pdb:2PXJ|rcsb pdb:2Q8C|rcsb pdb:2Q8D|rcsb pdb:2Q8E|rcsb pdb:2QQR|rcsb pdb:2QQS|rcsb pdb:2VD7|rcsb pdb:2WWJ|rcsb pdb:2YBK|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3NJY|rcsb pdb:3PDQ|rcsb pdb:3RVH|rcsb pdb:3U4S|rcsb pdb:4AI9|rcsb pdb:4BIS|rcsb pdb:4GD4|rcsb pdb:4URA|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:5A7N|rcsb pdb:5A7O|rcsb pdb:5A7P|rcsb pdb:5A7Q|rcsb pdb:5A7S|rcsb pdb:5A7W|rcsb pdb:5A80|rcsb pdb:5ANQ|rcsb pdb:5D6W|rcsb pdb:5D6X|rcsb pdb:5D6Y|rcsb pdb:5F2S|rcsb pdb:5F2W|rcsb pdb:5F32|rcsb pdb:5F37|rcsb pdb:5F39|rcsb pdb:5F3C|rcsb pdb:5F3E|rcsb pdb:5F3G|rcsb pdb:5F3I|rcsb pdb:5F5I|rcsb pdb:5FPV|rcsb pdb:5FWE|rcsb pdb:5FY8|rcsb pdb:5FYC|rcsb pdb:5FYH|rcsb pdb:5FYI|rcsb pdb:5LY1|rcsb pdb:5LY2|rcsb pdb:5TVR|rcsb pdb:5TVS|rcsb pdb:5VAR|rcsb pdb:5VGI|rcsb pdb:5VMP|rcsb pdb:6CG1|rcsb pdb:6CG2|rcsb pdb:6G5W|rcsb pdb:6G5X|rcsb pdb:6H4O|rcsb pdb:6H4P|rcsb pdb:6H4Q|rcsb pdb:6H4R|rcsb pdb:6H4S|rcsb pdb:6H4T|rcsb pdb:6H4U|rcsb pdb:6H4V|rcsb pdb:6H4W|rcsb pdb:6H4X|rcsb pdb:6H4Y|rcsb pdb:6H8P|rcsb pdb:6HGT|rcsb pdb:7D4A|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9029569 ensembl:ENSG00000157554(gene)|ensembl:ENST00000288319(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1SXE|rcsb pdb:4IRG|rcsb pdb:4IRH|rcsb pdb:4IRI|rcsb pdb:5YBC|rcsb pdb:5YBD|rcsb pdb:6VGE|rcsb pdb:6VGG|refseq:NP_001129626.1|refseq:NP_001129627.1|refseq:NP_001230357.1|refseq:NP_001230358.1|refseq:NP_001230361.1|refseq:NP_004440.1|refseq:NP_891548.1|refseq:NP_001278320.1|dip:DIP-31028N - - - figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/02/09 2020/08/14 rogid:P8atv/4zKIc7bVg3IZYlw5gVIHY9606 rogid:KJaYRzb5lsoL3V19T4l6qjjJfU09606 rigid:JXpqaj9J4zBWsFoMM6VAfmOEhJc false his tag:n-n|flag tag:n-n glutathione s tranferase tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)