#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P09733	uniprotkb:P02557	intact:EBI-18976|uniprotkb:D6W0J8|ensemblfungi:YML085C	intact:EBI-18986|uniprotkb:D6VTJ3|ensemblfungi:YFL037W	psi-mi:tba1_yeast(display_long)|uniprotkb:YML085C(locus name)|uniprotkb:TUB1(gene name)|psi-mi:TUB1(display_short)	psi-mi:tbb_yeast(display_long)|uniprotkb:YFL037W(locus name)|uniprotkb:TUB2(gene name)|psi-mi:TUB2(display_short)|uniprotkb:Beta-tubulin(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Howes et al. (2017)	pubmed:28652389|imex:IM-26227	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16632257|emdb:EMD-8755|emdb:EMD-8756|emdb:EMD-8757|imex:IM-26227-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YML085C(gene)|ensemblfungi:YML085C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000280"(nuclear division)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005827"(polar microtubule)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005874"(microtubule)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045298"(tubulin complex)|go:"GO:0098863"(nuclear migration by microtubule mediated pushing forces)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|rcsb pdb:4FFB|rcsb pdb:4U3J|rcsb pdb:5W3F|rcsb pdb:5W3H|rcsb pdb:5W3J|reactome:R-SCE-114608|refseq:NP_013625.1|sgd:S000004550|dip:DIP-854N|mint:P09733	ensemblfungi:YFL037W(gene)|ensemblfungi:YFL037W_mRNA(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005874"(microtubule)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007017"(microtubule-based process)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045298"(tubulin complex)|go:"GO:0046677"(response to antibiotic)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|rcsb pdb:4FFB|rcsb pdb:4U3J|rcsb pdb:5W3F|rcsb pdb:5W3H|rcsb pdb:5W3J|refseq:NP_116616.1|sgd:S000001857|dip:DIP-2340N|mint:P02557	-	crc64:E263B49440F71889	crc64:68EBEA7D7A5B8EA1	figure legend:N/A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/11/29	2017/11/29	rogid:SPNp3+7RZr0dO/P0VCbXlJTCOXg559292	rogid:kU3SKvNkJFLYaNy5pgPJGTYx2kc559292	rigid:fy6Y04yt2j2JwgEA65wiBLtKD9M	false	-	his tag:c-c	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
emdb:EMD-8755	uniprotkb:P40013	intact:EBI-16632272|emdb:EMD-8756|emdb:EMD-8757	intact:EBI-3614|uniprotkb:D3DLR4|ensemblfungi:YER016W	psi-mi:tub1-tub2_yeast(display_short)|psi-mi:EMD-8755(display_long)|intact:Tubulin alpha-beta heterodimeric complex, TUB1 variant(complex recommended name)|intact:"TUB1:TUB2"(complex systematic name)	psi-mi:bim1_yeast(display_long)|uniprotkb:BIM1(gene name)|psi-mi:BIM1(display_short)|uniprotkb:YER016W(locus name)	psi-mi:"MI:0040"(electron microscopy)	Howes et al. (2017)	pubmed:28652389|imex:IM-26227	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16717382|imex:IM-26227-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:1302"(stable complex)	psi-mi:"MI:0326"(protein)	intact:EBI-16632257(exp-evidence)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0045298"(tubulin complex)|go:"GO:0000226"(microtubule cytoskeleton organization)|pubmed:25957412(see-also)|complex portal:CPX-1424(complex-primary)|evidence ontology:"ECO:0000353"	refseq:NP_010932.1|sgd:S000000818|dip:DIP-1295N|mint:P40013|ensemblfungi:YER016W(gene)|ensemblfungi:YER016W_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0030543"(2-micrometer plasmid partitioning)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1904825"(protein localization to microtubule plus-end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR036133|interpro:IPR036872|rcsb pdb:2QJX|rcsb pdb:4E61|rcsb pdb:6FC6	-	curated-complex:Building block of the non-covalent cylindrical polymers that make up the hollow water-filled microtubule structures required for the migration and proper orientation of the nucleus, spindle pole body separation, spindle function, and nuclear division.|complex-properties:"Composed of a compact globular body and unstructured, negatively charged tubulin C-terminal tails. The C-terminal tails are regions of heavy post-translational modification (inclduing phosphorylation, acetylation, palmitoylation, sumoylation, polyamination, S-nitrosylation, glutamylation, glycylation) and serve as interaction sites for molecular motors and other associated proteins and thus can tune the activity of these effectors. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity."|complex-assembly:Heterodimer	crc64:C9087CB46A32BD74	figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/11/29	2018/01/04	-	rogid:UdSYdsJZ9fLO9XjYqOYoK1TzlDE559292	-	false	his tag:c-c(p02557)	sufficient binding region:1-210|enhanced green fluorescent protein tag:n-n|his tag:n-n	1	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)