#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P45973 intact:EBI-15634422 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 dip:DIP-29329N psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:h3k9-2(display_short)|psi-mi:EBI-15634422(display_long) psi-mi:"MI:0096"(pull down) Tchasovnikarova et al. (2015) pubmed:26022416|doi:"https://doi.org/10.1126/science.aaa7227"|imex:IM-24668 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16158143|imex:IM-24668-1|dip:DIP-199415E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N - psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:6M86IQcphd/YS8g0BNmUqxkx7Bk-2 rigid:tEoyZzuEGXmJ6yC3G1kO0GxvenU false - N6,N6-dimethyl-L-lysine:9-9|N6,N6,N6-trimethyl-L-lysine:9-9|biotin tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q99549 uniprotkb:Q9UK61 intact:EBI-2653928|uniprotkb:Q5JPE5|uniprotkb:Q9BTP1|uniprotkb:B7Z6F9|uniprotkb:Q5JTQ0|uniprotkb:Q96MK4|uniprotkb:Q86TK3|ensembl:ENSP00000355388 intact:EBI-308354|uniprotkb:A1L3A4|uniprotkb:B5ME28|uniprotkb:Q9H2F7|intact:EBI-2686962|intact:EBI-726790|uniprotkb:Q9UPP7|ensembl:ENSP00000508241 psi-mi:mpp8_human(display_long)|uniprotkb:MPP8(gene name synonym)|uniprotkb:Two hybrid-associated protein 3 with RanBPM(gene name synonym)|uniprotkb:MPHOSPH8(gene name)|psi-mi:MPHOSPH8(display_short) psi-mi:tasor_human(display_long)|uniprotkb:TASOR(gene name)|psi-mi:TASOR(display_short)|uniprotkb:C3orf63(gene name synonym)|uniprotkb:CTCL tumor antigen se89-1(gene name synonym)|uniprotkb:FAM208A(gene name synonym)|uniprotkb:KIAA1105(gene name synonym)|uniprotkb:Retinoblastoma-associated protein RAP140(gene name synonym)|uniprotkb:Transgene activation suppressor protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tchasovnikarova et al. (2015) pubmed:26022416|doi:"https://doi.org/10.1126/science.aaa7227"|imex:IM-24668 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16158168|imex:IM-24668-2|dip:DIP-199411E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_059990.2|dip:DIP-56224N|ensembl:ENSG00000196199(gene)|ensembl:ENST00000361479(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR002110(Ankyrin)|interpro:IPR016197(Chromo domain-like)|interpro:IPR020683|interpro:IPR023779|interpro:IPR023780|interpro:IPR036770|rcsb pdb:3LWE|rcsb pdb:3QO2|rcsb pdb:3R93|rcsb pdb:3SVM|rcsb pdb:6V2S go:"GO:0097355"(protein localization to heterochromatin)|interpro:IPR022188|mint:Q9UK61|rcsb pdb:6SWG|rcsb pdb:6TL1|ensembl:ENSG00000163946(gene)|ensembl:ENST00000683822(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0060809"(mesodermal to mesenchymal transition involved in gastrulation)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|refseq:NP_001106207.1|refseq:NP_056039.2|refseq:XP_005265056.1|refseq:XP_011531854.1|dip:DIP-56150N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:9QQ9BhqAsSk3vld/WxlewgUX+l09606 rogid:4gCWI/avGs3xJZtDtW9+bguXx3o9606 rigid:8ydbZiH9ivEtMaQkqYG7cXcUdck false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-15634422 uniprotkb:P45973 dip:DIP-29329N intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 psi-mi:h3k9-2(display_short)|psi-mi:EBI-15634422(display_long) psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:"MI:0096"(pull down) Tchasovnikarova et al. (2015) pubmed:26022416|doi:"https://doi.org/10.1126/science.aaa7227"|imex:IM-24668 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16158185|imex:IM-24668-3|dip:DIP-199414E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:6M86IQcphd/YS8g0BNmUqxkx7Bk-2 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rigid:m1hXS+ahMtEVW4jnNhDzhtW6/aw false N6,N6-dimethyl-L-lysine:9-9|N6,N6,N6-trimethyl-L-lysine:9-9|biotin tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-15634422 uniprotkb:Q99549 dip:DIP-29329N intact:EBI-2653928|uniprotkb:Q5JPE5|uniprotkb:Q9BTP1|uniprotkb:B7Z6F9|uniprotkb:Q5JTQ0|uniprotkb:Q96MK4|uniprotkb:Q86TK3|ensembl:ENSP00000355388 psi-mi:h3k9-2(display_short)|psi-mi:EBI-15634422(display_long) psi-mi:mpp8_human(display_long)|uniprotkb:MPP8(gene name synonym)|uniprotkb:Two hybrid-associated protein 3 with RanBPM(gene name synonym)|uniprotkb:MPHOSPH8(gene name)|psi-mi:MPHOSPH8(display_short) psi-mi:"MI:0096"(pull down) Tchasovnikarova et al. (2015) pubmed:26022416|doi:"https://doi.org/10.1126/science.aaa7227"|imex:IM-24668 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16158185|imex:IM-24668-3|dip:DIP-199414E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - refseq:NP_059990.2|dip:DIP-56224N|ensembl:ENSG00000196199(gene)|ensembl:ENST00000361479(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR002110(Ankyrin)|interpro:IPR016197(Chromo domain-like)|interpro:IPR020683|interpro:IPR023779|interpro:IPR023780|interpro:IPR036770|rcsb pdb:3LWE|rcsb pdb:3QO2|rcsb pdb:3R93|rcsb pdb:3SVM|rcsb pdb:6V2S psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:6M86IQcphd/YS8g0BNmUqxkx7Bk-2 rogid:9QQ9BhqAsSk3vld/WxlewgUX+l09606 rigid:m1hXS+ahMtEVW4jnNhDzhtW6/aw false N6,N6-dimethyl-L-lysine:9-9|N6,N6,N6-trimethyl-L-lysine:9-9|biotin tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-15634422 uniprotkb:Q9UK61 dip:DIP-29329N intact:EBI-308354|uniprotkb:A1L3A4|uniprotkb:B5ME28|uniprotkb:Q9H2F7|intact:EBI-2686962|intact:EBI-726790|uniprotkb:Q9UPP7|ensembl:ENSP00000508241 psi-mi:h3k9-2(display_short)|psi-mi:EBI-15634422(display_long) psi-mi:tasor_human(display_long)|uniprotkb:TASOR(gene name)|psi-mi:TASOR(display_short)|uniprotkb:C3orf63(gene name synonym)|uniprotkb:CTCL tumor antigen se89-1(gene name synonym)|uniprotkb:FAM208A(gene name synonym)|uniprotkb:KIAA1105(gene name synonym)|uniprotkb:Retinoblastoma-associated protein RAP140(gene name synonym)|uniprotkb:Transgene activation suppressor protein(gene name synonym) psi-mi:"MI:0096"(pull down) Tchasovnikarova et al. (2015) pubmed:26022416|doi:"https://doi.org/10.1126/science.aaa7227"|imex:IM-24668 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16158185|imex:IM-24668-3|dip:DIP-199414E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - go:"GO:0097355"(protein localization to heterochromatin)|interpro:IPR022188|mint:Q9UK61|rcsb pdb:6SWG|rcsb pdb:6TL1|ensembl:ENSG00000163946(gene)|ensembl:ENST00000683822(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0060809"(mesodermal to mesenchymal transition involved in gastrulation)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|refseq:NP_001106207.1|refseq:NP_056039.2|refseq:XP_005265056.1|refseq:XP_011531854.1|dip:DIP-56150N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:6M86IQcphd/YS8g0BNmUqxkx7Bk-2 rogid:4gCWI/avGs3xJZtDtW9+bguXx3o9606 rigid:m1hXS+ahMtEVW4jnNhDzhtW6/aw false N6,N6-dimethyl-L-lysine:9-9|N6,N6,N6-trimethyl-L-lysine:9-9|biotin tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q15047 uniprotkb:Q99549 intact:EBI-79691|ensembl:ENSP00000271640|uniprotkb:A6NEW2|uniprotkb:Q5SZD8|uniprotkb:Q5SZD9|uniprotkb:Q5SZE0|uniprotkb:Q5SZE7|uniprotkb:Q96GM9 intact:EBI-2653928|uniprotkb:Q5JPE5|uniprotkb:Q9BTP1|uniprotkb:B7Z6F9|uniprotkb:Q5JTQ0|uniprotkb:Q96MK4|uniprotkb:Q86TK3|ensembl:ENSP00000355388 psi-mi:setb1_human(display_long)|uniprotkb:SETDB1(gene name)|psi-mi:SETDB1(display_short)|uniprotkb:KIAA0067(gene name synonym)|uniprotkb:KMT1E(gene name synonym)|uniprotkb:SET domain bifurcated 1(gene name synonym)|uniprotkb:ERG-associated protein with SET domain(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 4(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1E(gene name synonym)|uniprotkb:ESET(gene name synonym) psi-mi:mpp8_human(display_long)|uniprotkb:MPP8(gene name synonym)|uniprotkb:Two hybrid-associated protein 3 with RanBPM(gene name synonym)|uniprotkb:MPHOSPH8(gene name)|psi-mi:MPHOSPH8(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tchasovnikarova et al. (2015) pubmed:26022416|doi:"https://doi.org/10.1126/science.aaa7227"|imex:IM-24668 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16158212|imex:IM-24668-4|dip:DIP-199413E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143379(gene)|ensembl:ENST00000271640(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0005694"(chromosome)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033273"(response to vitamin)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045471"(response to ethanol)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR002999(Tudor)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR025796|interpro:IPR040880|interpro:IPR041291|interpro:IPR041292|mint:Q15047|rcsb pdb:3DLM|rcsb pdb:4X3S|rcsb pdb:5KCH|rcsb pdb:5KCO|rcsb pdb:5KE2|rcsb pdb:5KE3|rcsb pdb:5KH6|rcsb pdb:5QT1|rcsb pdb:5QT2|rcsb pdb:6AU2|rcsb pdb:6AU3|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6BPI|rcsb pdb:7C9N|rcsb pdb:7CAJ|rcsb pdb:7CD9|rcsb pdb:7CJT|reactome:R-HSA-3214841|refseq:NP_001138887.1|refseq:NP_001230420.1|refseq:NP_036564.3|refseq:XP_016858444.1|dip:DIP-31029N refseq:NP_059990.2|dip:DIP-56224N|ensembl:ENSG00000196199(gene)|ensembl:ENST00000361479(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR002110(Ankyrin)|interpro:IPR016197(Chromo domain-like)|interpro:IPR020683|interpro:IPR023779|interpro:IPR023780|interpro:IPR036770|rcsb pdb:3LWE|rcsb pdb:3QO2|rcsb pdb:3R93|rcsb pdb:3SVM|rcsb pdb:6V2S psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:ydyGndAZ5b35jF07y4WFUeHFFvE9606 rogid:9QQ9BhqAsSk3vld/WxlewgUX+l09606 rigid:WSkntFh3Sec0xqoscmllbU/exdc false myc tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15047 uniprotkb:Q9UK61 intact:EBI-79691|ensembl:ENSP00000271640|uniprotkb:A6NEW2|uniprotkb:Q5SZD8|uniprotkb:Q5SZD9|uniprotkb:Q5SZE0|uniprotkb:Q5SZE7|uniprotkb:Q96GM9 intact:EBI-308354|uniprotkb:A1L3A4|uniprotkb:B5ME28|uniprotkb:Q9H2F7|intact:EBI-2686962|intact:EBI-726790|uniprotkb:Q9UPP7|ensembl:ENSP00000508241 psi-mi:setb1_human(display_long)|uniprotkb:SETDB1(gene name)|psi-mi:SETDB1(display_short)|uniprotkb:KIAA0067(gene name synonym)|uniprotkb:KMT1E(gene name synonym)|uniprotkb:SET domain bifurcated 1(gene name synonym)|uniprotkb:ERG-associated protein with SET domain(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 4(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1E(gene name synonym)|uniprotkb:ESET(gene name synonym) psi-mi:tasor_human(display_long)|uniprotkb:TASOR(gene name)|psi-mi:TASOR(display_short)|uniprotkb:C3orf63(gene name synonym)|uniprotkb:CTCL tumor antigen se89-1(gene name synonym)|uniprotkb:FAM208A(gene name synonym)|uniprotkb:KIAA1105(gene name synonym)|uniprotkb:Retinoblastoma-associated protein RAP140(gene name synonym)|uniprotkb:Transgene activation suppressor protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tchasovnikarova et al. (2015) pubmed:26022416|doi:"https://doi.org/10.1126/science.aaa7227"|imex:IM-24668 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16158212|imex:IM-24668-4|dip:DIP-199413E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143379(gene)|ensembl:ENST00000271640(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0005694"(chromosome)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033273"(response to vitamin)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045471"(response to ethanol)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR002999(Tudor)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR025796|interpro:IPR040880|interpro:IPR041291|interpro:IPR041292|mint:Q15047|rcsb pdb:3DLM|rcsb pdb:4X3S|rcsb pdb:5KCH|rcsb pdb:5KCO|rcsb pdb:5KE2|rcsb pdb:5KE3|rcsb pdb:5KH6|rcsb pdb:5QT1|rcsb pdb:5QT2|rcsb pdb:6AU2|rcsb pdb:6AU3|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6BPI|rcsb pdb:7C9N|rcsb pdb:7CAJ|rcsb pdb:7CD9|rcsb pdb:7CJT|reactome:R-HSA-3214841|refseq:NP_001138887.1|refseq:NP_001230420.1|refseq:NP_036564.3|refseq:XP_016858444.1|dip:DIP-31029N go:"GO:0097355"(protein localization to heterochromatin)|interpro:IPR022188|mint:Q9UK61|rcsb pdb:6SWG|rcsb pdb:6TL1|ensembl:ENSG00000163946(gene)|ensembl:ENST00000683822(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0060809"(mesodermal to mesenchymal transition involved in gastrulation)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|refseq:NP_001106207.1|refseq:NP_056039.2|refseq:XP_005265056.1|refseq:XP_011531854.1|dip:DIP-56150N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:ydyGndAZ5b35jF07y4WFUeHFFvE9606 rogid:4gCWI/avGs3xJZtDtW9+bguXx3o9606 rigid:WSkntFh3Sec0xqoscmllbU/exdc false myc tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99549 uniprotkb:Q9UK61 intact:EBI-2653928|uniprotkb:Q5JPE5|uniprotkb:Q9BTP1|uniprotkb:B7Z6F9|uniprotkb:Q5JTQ0|uniprotkb:Q96MK4|uniprotkb:Q86TK3|ensembl:ENSP00000355388 intact:EBI-308354|uniprotkb:A1L3A4|uniprotkb:B5ME28|uniprotkb:Q9H2F7|intact:EBI-2686962|intact:EBI-726790|uniprotkb:Q9UPP7|ensembl:ENSP00000508241 psi-mi:mpp8_human(display_long)|uniprotkb:MPP8(gene name synonym)|uniprotkb:Two hybrid-associated protein 3 with RanBPM(gene name synonym)|uniprotkb:MPHOSPH8(gene name)|psi-mi:MPHOSPH8(display_short) psi-mi:tasor_human(display_long)|uniprotkb:TASOR(gene name)|psi-mi:TASOR(display_short)|uniprotkb:C3orf63(gene name synonym)|uniprotkb:CTCL tumor antigen se89-1(gene name synonym)|uniprotkb:FAM208A(gene name synonym)|uniprotkb:KIAA1105(gene name synonym)|uniprotkb:Retinoblastoma-associated protein RAP140(gene name synonym)|uniprotkb:Transgene activation suppressor protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tchasovnikarova et al. (2015) pubmed:26022416|doi:"https://doi.org/10.1126/science.aaa7227"|imex:IM-24668 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16158232|imex:IM-24668-5|dip:DIP-199411E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_059990.2|dip:DIP-56224N|ensembl:ENSG00000196199(gene)|ensembl:ENST00000361479(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR002110(Ankyrin)|interpro:IPR016197(Chromo domain-like)|interpro:IPR020683|interpro:IPR023779|interpro:IPR023780|interpro:IPR036770|rcsb pdb:3LWE|rcsb pdb:3QO2|rcsb pdb:3R93|rcsb pdb:3SVM|rcsb pdb:6V2S go:"GO:0097355"(protein localization to heterochromatin)|interpro:IPR022188|mint:Q9UK61|rcsb pdb:6SWG|rcsb pdb:6TL1|ensembl:ENSG00000163946(gene)|ensembl:ENST00000683822(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0060809"(mesodermal to mesenchymal transition involved in gastrulation)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|refseq:NP_001106207.1|refseq:NP_056039.2|refseq:XP_005265056.1|refseq:XP_011531854.1|dip:DIP-56150N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:9QQ9BhqAsSk3vld/WxlewgUX+l09606 rogid:4gCWI/avGs3xJZtDtW9+bguXx3o9606 rigid:8ydbZiH9ivEtMaQkqYG7cXcUdck false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NEY8 uniprotkb:Q99549 intact:EBI-474076|uniprotkb:Q86YT2|uniprotkb:Q8IXN3|uniprotkb:Q8TB09|uniprotkb:Q96NB9|uniprotkb:Q9NXL4|uniprotkb:Q9P0P6|uniprotkb:Q9P0R9|uniprotkb:E9PAX8|ensembl:ENSP00000378935|ensembl:ENSP00000479913 intact:EBI-2653928|uniprotkb:Q5JPE5|uniprotkb:Q9BTP1|uniprotkb:B7Z6F9|uniprotkb:Q5JTQ0|uniprotkb:Q96MK4|uniprotkb:Q86TK3|ensembl:ENSP00000355388 psi-mi:pphln_human(display_long)|uniprotkb:Gastric cancer antigen Ga50(gene name synonym)|uniprotkb:HSPC206(orf name)|uniprotkb:HSPC232(orf name)|uniprotkb:PPHLN1(gene name)|psi-mi:PPHLN1(display_short)|uniprotkb:CDC7 expression repressor(gene name synonym) psi-mi:mpp8_human(display_long)|uniprotkb:MPP8(gene name synonym)|uniprotkb:Two hybrid-associated protein 3 with RanBPM(gene name synonym)|uniprotkb:MPHOSPH8(gene name)|psi-mi:MPHOSPH8(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tchasovnikarova et al. (2015) pubmed:26022416|doi:"https://doi.org/10.1126/science.aaa7227"|imex:IM-24668 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16158249|imex:IM-24668-6|dip:DIP-199412E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137259.1|refseq:NP_001137260.1|refseq:NP_057572.5|refseq:NP_958846.1|refseq:NP_958847.1|refseq:NP_958848.1|refseq:NP_958923.1|dip:DIP-49051N|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031424"(keratinization)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0097355"(protein localization to heterochromatin)|interpro:IPR028851|mint:Q8NEY8|rcsb pdb:6SWG|ensembl:ENSG00000134283(gene)|ensembl:ENST00000395568(transcript)|ensembl:ENST00000610488(transcript) refseq:NP_059990.2|dip:DIP-56224N|ensembl:ENSG00000196199(gene)|ensembl:ENST00000361479(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR002110(Ankyrin)|interpro:IPR016197(Chromo domain-like)|interpro:IPR020683|interpro:IPR023779|interpro:IPR023780|interpro:IPR036770|rcsb pdb:3LWE|rcsb pdb:3QO2|rcsb pdb:3R93|rcsb pdb:3SVM|rcsb pdb:6V2S psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:+s8KstGQ7d91qe3DDnpKYMJon7o9606 rogid:9QQ9BhqAsSk3vld/WxlewgUX+l09606 rigid:YxO4NRxWMwvJckPsU+gMa8X+osc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NEY8 uniprotkb:Q9UK61 intact:EBI-474076|uniprotkb:Q86YT2|uniprotkb:Q8IXN3|uniprotkb:Q8TB09|uniprotkb:Q96NB9|uniprotkb:Q9NXL4|uniprotkb:Q9P0P6|uniprotkb:Q9P0R9|uniprotkb:E9PAX8|ensembl:ENSP00000378935|ensembl:ENSP00000479913 intact:EBI-308354|uniprotkb:A1L3A4|uniprotkb:B5ME28|uniprotkb:Q9H2F7|intact:EBI-2686962|intact:EBI-726790|uniprotkb:Q9UPP7|ensembl:ENSP00000508241 psi-mi:pphln_human(display_long)|uniprotkb:Gastric cancer antigen Ga50(gene name synonym)|uniprotkb:HSPC206(orf name)|uniprotkb:HSPC232(orf name)|uniprotkb:PPHLN1(gene name)|psi-mi:PPHLN1(display_short)|uniprotkb:CDC7 expression repressor(gene name synonym) psi-mi:tasor_human(display_long)|uniprotkb:TASOR(gene name)|psi-mi:TASOR(display_short)|uniprotkb:C3orf63(gene name synonym)|uniprotkb:CTCL tumor antigen se89-1(gene name synonym)|uniprotkb:FAM208A(gene name synonym)|uniprotkb:KIAA1105(gene name synonym)|uniprotkb:Retinoblastoma-associated protein RAP140(gene name synonym)|uniprotkb:Transgene activation suppressor protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tchasovnikarova et al. (2015) pubmed:26022416|doi:"https://doi.org/10.1126/science.aaa7227"|imex:IM-24668 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16158249|imex:IM-24668-6|dip:DIP-199412E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137259.1|refseq:NP_001137260.1|refseq:NP_057572.5|refseq:NP_958846.1|refseq:NP_958847.1|refseq:NP_958848.1|refseq:NP_958923.1|dip:DIP-49051N|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031424"(keratinization)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0097355"(protein localization to heterochromatin)|interpro:IPR028851|mint:Q8NEY8|rcsb pdb:6SWG|ensembl:ENSG00000134283(gene)|ensembl:ENST00000395568(transcript)|ensembl:ENST00000610488(transcript) go:"GO:0097355"(protein localization to heterochromatin)|interpro:IPR022188|mint:Q9UK61|rcsb pdb:6SWG|rcsb pdb:6TL1|ensembl:ENSG00000163946(gene)|ensembl:ENST00000683822(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0060809"(mesodermal to mesenchymal transition involved in gastrulation)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|refseq:NP_001106207.1|refseq:NP_056039.2|refseq:XP_005265056.1|refseq:XP_011531854.1|dip:DIP-56150N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:+s8KstGQ7d91qe3DDnpKYMJon7o9606 rogid:4gCWI/avGs3xJZtDtW9+bguXx3o9606 rigid:YxO4NRxWMwvJckPsU+gMa8X+osc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UK61 uniprotkb:Q8NEY8 intact:EBI-308354|uniprotkb:A1L3A4|uniprotkb:B5ME28|uniprotkb:Q9H2F7|intact:EBI-2686962|intact:EBI-726790|uniprotkb:Q9UPP7|ensembl:ENSP00000508241 intact:EBI-474076|uniprotkb:Q86YT2|uniprotkb:Q8IXN3|uniprotkb:Q8TB09|uniprotkb:Q96NB9|uniprotkb:Q9NXL4|uniprotkb:Q9P0P6|uniprotkb:Q9P0R9|uniprotkb:E9PAX8|ensembl:ENSP00000378935|ensembl:ENSP00000479913 psi-mi:tasor_human(display_long)|uniprotkb:TASOR(gene name)|psi-mi:TASOR(display_short)|uniprotkb:C3orf63(gene name synonym)|uniprotkb:CTCL tumor antigen se89-1(gene name synonym)|uniprotkb:FAM208A(gene name synonym)|uniprotkb:KIAA1105(gene name synonym)|uniprotkb:Retinoblastoma-associated protein RAP140(gene name synonym)|uniprotkb:Transgene activation suppressor protein(gene name synonym) psi-mi:pphln_human(display_long)|uniprotkb:Gastric cancer antigen Ga50(gene name synonym)|uniprotkb:HSPC206(orf name)|uniprotkb:HSPC232(orf name)|uniprotkb:PPHLN1(gene name)|psi-mi:PPHLN1(display_short)|uniprotkb:CDC7 expression repressor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tchasovnikarova et al. (2015) pubmed:26022416|doi:"https://doi.org/10.1126/science.aaa7227"|imex:IM-24668 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16158267|imex:IM-24668-7|dip:DIP-199412E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097355"(protein localization to heterochromatin)|interpro:IPR022188|mint:Q9UK61|rcsb pdb:6SWG|rcsb pdb:6TL1|ensembl:ENSG00000163946(gene)|ensembl:ENST00000683822(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0060809"(mesodermal to mesenchymal transition involved in gastrulation)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|refseq:NP_001106207.1|refseq:NP_056039.2|refseq:XP_005265056.1|refseq:XP_011531854.1|dip:DIP-56150N refseq:NP_001137259.1|refseq:NP_001137260.1|refseq:NP_057572.5|refseq:NP_958846.1|refseq:NP_958847.1|refseq:NP_958848.1|refseq:NP_958923.1|dip:DIP-49051N|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031424"(keratinization)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0097355"(protein localization to heterochromatin)|interpro:IPR028851|mint:Q8NEY8|rcsb pdb:6SWG|ensembl:ENSG00000134283(gene)|ensembl:ENST00000395568(transcript)|ensembl:ENST00000610488(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:4gCWI/avGs3xJZtDtW9+bguXx3o9606 rogid:+s8KstGQ7d91qe3DDnpKYMJon7o9606 rigid:YxO4NRxWMwvJckPsU+gMa8X+osc false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9UK61 uniprotkb:Q99549 intact:EBI-308354|uniprotkb:A1L3A4|uniprotkb:B5ME28|uniprotkb:Q9H2F7|intact:EBI-2686962|intact:EBI-726790|uniprotkb:Q9UPP7|ensembl:ENSP00000508241 intact:EBI-2653928|uniprotkb:Q5JPE5|uniprotkb:Q9BTP1|uniprotkb:B7Z6F9|uniprotkb:Q5JTQ0|uniprotkb:Q96MK4|uniprotkb:Q86TK3|ensembl:ENSP00000355388 psi-mi:tasor_human(display_long)|uniprotkb:TASOR(gene name)|psi-mi:TASOR(display_short)|uniprotkb:C3orf63(gene name synonym)|uniprotkb:CTCL tumor antigen se89-1(gene name synonym)|uniprotkb:FAM208A(gene name synonym)|uniprotkb:KIAA1105(gene name synonym)|uniprotkb:Retinoblastoma-associated protein RAP140(gene name synonym)|uniprotkb:Transgene activation suppressor protein(gene name synonym) psi-mi:mpp8_human(display_long)|uniprotkb:MPP8(gene name synonym)|uniprotkb:Two hybrid-associated protein 3 with RanBPM(gene name synonym)|uniprotkb:MPHOSPH8(gene name)|psi-mi:MPHOSPH8(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tchasovnikarova et al. (2015) pubmed:26022416|doi:"https://doi.org/10.1126/science.aaa7227"|imex:IM-24668 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16158267|imex:IM-24668-7|dip:DIP-199412E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097355"(protein localization to heterochromatin)|interpro:IPR022188|mint:Q9UK61|rcsb pdb:6SWG|rcsb pdb:6TL1|ensembl:ENSG00000163946(gene)|ensembl:ENST00000683822(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0060809"(mesodermal to mesenchymal transition involved in gastrulation)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|refseq:NP_001106207.1|refseq:NP_056039.2|refseq:XP_005265056.1|refseq:XP_011531854.1|dip:DIP-56150N refseq:NP_059990.2|dip:DIP-56224N|ensembl:ENSG00000196199(gene)|ensembl:ENST00000361479(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR002110(Ankyrin)|interpro:IPR016197(Chromo domain-like)|interpro:IPR020683|interpro:IPR023779|interpro:IPR023780|interpro:IPR036770|rcsb pdb:3LWE|rcsb pdb:3QO2|rcsb pdb:3R93|rcsb pdb:3SVM|rcsb pdb:6V2S psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:4gCWI/avGs3xJZtDtW9+bguXx3o9606 rogid:9QQ9BhqAsSk3vld/WxlewgUX+l09606 rigid:YxO4NRxWMwvJckPsU+gMa8X+osc false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) intact:EBI-15634422 uniprotkb:Q99549 dip:DIP-29329N intact:EBI-2653928|uniprotkb:Q5JPE5|uniprotkb:Q9BTP1|uniprotkb:B7Z6F9|uniprotkb:Q5JTQ0|uniprotkb:Q96MK4|uniprotkb:Q86TK3|ensembl:ENSP00000355388 psi-mi:h3k9-2(display_short)|psi-mi:EBI-15634422(display_long) psi-mi:mpp8_human(display_long)|uniprotkb:MPP8(gene name synonym)|uniprotkb:Two hybrid-associated protein 3 with RanBPM(gene name synonym)|uniprotkb:MPHOSPH8(gene name)|psi-mi:MPHOSPH8(display_short) psi-mi:"MI:0096"(pull down) Tchasovnikarova et al. (2015) pubmed:26022416|doi:"https://doi.org/10.1126/science.aaa7227"|imex:IM-24668 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16158286|imex:IM-24668-8|dip:DIP-199416E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - refseq:NP_059990.2|dip:DIP-56224N|ensembl:ENSG00000196199(gene)|ensembl:ENST00000361479(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR002110(Ankyrin)|interpro:IPR016197(Chromo domain-like)|interpro:IPR020683|interpro:IPR023779|interpro:IPR023780|interpro:IPR036770|rcsb pdb:3LWE|rcsb pdb:3QO2|rcsb pdb:3R93|rcsb pdb:3SVM|rcsb pdb:6V2S psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:6M86IQcphd/YS8g0BNmUqxkx7Bk-2 rogid:9QQ9BhqAsSk3vld/WxlewgUX+l09606 rigid:EPQGHv2EKgSRmXWmU/X5/UnVJZ8 false monomethylated L-lysine:9-9|biotin tag:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)