#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O35613 uniprotkb:P84244 intact:EBI-77304|uniprotkb:Q9QWT8|uniprotkb:Q9QWV3 intact:EBI-120681|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q3TW79|uniprotkb:Q3U6D6|uniprotkb:Q569U8|uniprotkb:Q5HZY8|uniprotkb:Q6TXQ5|uniprotkb:Q8VDJ2|uniprotkb:Q9D0H3|uniprotkb:Q9V3W4|ensembl:ENSMUSP00000016703|ensembl:ENSMUSP00000102062|ensembl:ENSMUSP00000124509|ensembl:ENSMUSP00000125104 psi-mi:daxx_mouse(display_long)|uniprotkb:Daxx(gene name)|psi-mi:Daxx(display_short)|uniprotkb:Daxx(gene name synonym) psi-mi:h33_mouse(display_long)|uniprotkb:H3-3a(gene name)|psi-mi:H3-3a(display_short)|uniprotkb:H3-3b(gene name)|psi-mi:H3-3b(display_short)|uniprotkb:H3.3a(gene name synonym)|uniprotkb:H3.3b(gene name synonym)|uniprotkb:H3f3a(gene name synonym)|uniprotkb:H3f3b(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Elsässer et al. (2015) pubmed:25938714|doi:10.1038/nature14345|imex:IM-24567 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16155910|imex:IM-24567-1|dip:DIP-199214E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186662.1|refseq:NP_031855.3|refseq:XP_006523644.1|refseq:XP_006523645.1|mint:O35613|dip:DIP-30972N|refseq:XP_006523643.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0001741"(XY body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019894"(kinesin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030578"(PML body organization)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|reactome:R-MMU-3899300|reactome:R-MMU-6804757|reactome:R-MMU-9670095 refseq:NP_032236.1|refseq:NP_032237.1|ensembl:ENSMUSG00000016559(gene)|ensembl:ENSMUSG00000060743(gene)|ensembl:ENSMUST00000016703(transcript)|ensembl:ENSMUST00000106454(transcript)|ensembl:ENSMUST00000161308(transcript)|ensembl:ENSMUST00000162814(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001740"(Barr body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006997"(nucleus organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007420"(brain development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0007286"(spermatid development)|go:"GO:0009725"(response to hormone)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:1902340"(negative regulation of chromosome condensation)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84244|rcsb pdb:2RVN|rcsb pdb:5XM0|rcsb pdb:5XM1|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-427359|reactome:R-MMU-427413|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-5625886|reactome:R-MMU-73728|reactome:R-MMU-73772|reactome:R-MMU-9018519|reactome:R-MMU-983231|reactome:R-MMU-8936459|refseq:XP_006532311.1|dip:DIP-35190N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/08 2017/08/10 rogid:/tlUn6VH6raf1J1r07iaYyKarek10090 rogid:cRqA5/IBNfIbbxAnbwLqzXip20I10090 rigid:hDTvv0JXvnzP/fdkm1T504zf9Gw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O35613 uniprotkb:Q62318 intact:EBI-77304|uniprotkb:Q9QWT8|uniprotkb:Q9QWV3 intact:EBI-346909|uniprotkb:P70391|uniprotkb:Q8C283|uniprotkb:Q99PN4|ensembl:ENSMUSP00000005705 psi-mi:daxx_mouse(display_long)|uniprotkb:Daxx(gene name)|psi-mi:Daxx(display_short)|uniprotkb:Daxx(gene name synonym) psi-mi:tif1b_mouse(display_long)|uniprotkb:Trim28(gene name)|psi-mi:Trim28(display_short)|uniprotkb:Krip1(gene name synonym)|uniprotkb:Tif1b(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:KRAB-A-interacting protein(gene name synonym)|uniprotkb:KRIP-1(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:Kap1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Elsässer et al. (2015) pubmed:25938714|doi:10.1038/nature14345|imex:IM-24567 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16155910|imex:IM-24567-1|dip:DIP-199214E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186662.1|refseq:NP_031855.3|refseq:XP_006523644.1|refseq:XP_006523645.1|mint:O35613|dip:DIP-30972N|refseq:XP_006523643.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0001741"(XY body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019894"(kinesin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030578"(PML body organization)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|reactome:R-MMU-3899300|reactome:R-MMU-6804757|reactome:R-MMU-9670095 refseq:NP_035718.2|dip:DIP-31477N|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q62318|rcsb pdb:6O5K|reactome:R-MMU-212436|ensembl:ENSMUSG00000005566(gene)|ensembl:ENSMUST00000005705(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006468"(protein phosphorylation) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/08 2017/08/10 rogid:/tlUn6VH6raf1J1r07iaYyKarek10090 rogid:DvGJxQNohVWs++QEAyrqe4ngcz810090 rigid:hDTvv0JXvnzP/fdkm1T504zf9Gw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O35613 uniprotkb:Q61687 intact:EBI-77304|uniprotkb:Q9QWT8|uniprotkb:Q9QWV3 intact:EBI-2657527|intact:EBI-2658449|uniprotkb:A2ADH4|ensembl:ENSMUSP00000109203 psi-mi:daxx_mouse(display_long)|uniprotkb:Daxx(gene name)|psi-mi:Daxx(display_short)|uniprotkb:Daxx(gene name synonym) psi-mi:atrx_mouse(display_long)|uniprotkb:Xnp(gene name synonym)|uniprotkb:ATP-dependent helicase ATRX(gene name synonym)|uniprotkb:HP1 alpha-interacting protein(gene name synonym)|uniprotkb:HP1-BP38 protein(gene name synonym)|uniprotkb:Heterochromatin protein 2(gene name synonym)|uniprotkb:X-linked nuclear protein(gene name synonym)|uniprotkb:Atrx(gene name)|psi-mi:Atrx(display_short)|uniprotkb:Hp1bp2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Elsässer et al. (2015) pubmed:25938714|doi:10.1038/nature14345|imex:IM-24567 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16155910|imex:IM-24567-1|dip:DIP-199214E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186662.1|refseq:NP_031855.3|refseq:XP_006523644.1|refseq:XP_006523645.1|mint:O35613|dip:DIP-30972N|refseq:XP_006523643.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0001741"(XY body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019894"(kinesin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030578"(PML body organization)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|reactome:R-MMU-3899300|reactome:R-MMU-6804757|reactome:R-MMU-9670095 refseq:NP_033556.2|interpro:IPR038718|interpro:IPR041430|mint:Q61687|reactome:R-MMU-9670095|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900112"(regulation of histone H3-K9 trimethylation)|go:"GO:1901581"(negative regulation of telomeric RNA transcription from RNA pol II promoter)|go:"GO:1901582"(positive regulation of telomeric RNA transcription from RNA pol II promoter)|go:"GO:1904908"(negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR025766|interpro:IPR027417|ensembl:ENSMUSG00000031229(gene)|ensembl:ENSMUST00000113573(transcript)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030900"(forebrain development)|go:"GO:0031297"(replication fork processing)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035128"(post-embryonic forelimb morphogenesis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060009"(Sertoli cell development)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070615"|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0072711"(cellular response to hydroxyurea)|dip:DIP-55974N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/08 2017/08/10 rogid:/tlUn6VH6raf1J1r07iaYyKarek10090 rogid:dZfE7Or8WAgkuHkmUcqC3UlWi7U10090 rigid:hDTvv0JXvnzP/fdkm1T504zf9Gw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q62318 uniprotkb:O35613 intact:EBI-346909|uniprotkb:P70391|uniprotkb:Q8C283|uniprotkb:Q99PN4|ensembl:ENSMUSP00000005705 intact:EBI-77304|uniprotkb:Q9QWT8|uniprotkb:Q9QWV3 psi-mi:tif1b_mouse(display_long)|uniprotkb:Trim28(gene name)|psi-mi:Trim28(display_short)|uniprotkb:Krip1(gene name synonym)|uniprotkb:Tif1b(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:KRAB-A-interacting protein(gene name synonym)|uniprotkb:KRIP-1(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:Kap1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:daxx_mouse(display_long)|uniprotkb:Daxx(gene name)|psi-mi:Daxx(display_short)|uniprotkb:Daxx(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Elsässer et al. (2015) pubmed:25938714|doi:10.1038/nature14345|imex:IM-24567 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16155929|imex:IM-24567-2|dip:DIP-199215E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035718.2|dip:DIP-31477N|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q62318|rcsb pdb:6O5K|reactome:R-MMU-212436|ensembl:ENSMUSG00000005566(gene)|ensembl:ENSMUST00000005705(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006468"(protein phosphorylation) refseq:NP_001186662.1|refseq:NP_031855.3|refseq:XP_006523644.1|refseq:XP_006523645.1|mint:O35613|dip:DIP-30972N|refseq:XP_006523643.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0001741"(XY body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019894"(kinesin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030578"(PML body organization)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|reactome:R-MMU-3899300|reactome:R-MMU-6804757|reactome:R-MMU-9670095 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/08 2017/08/10 rogid:DvGJxQNohVWs++QEAyrqe4ngcz810090 rogid:/tlUn6VH6raf1J1r07iaYyKarek10090 rigid:wU6XpyV2HRsQ3udUj2r4jwcrILw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)