#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P45956	uniprotkb:Q46896	intact:EBI-9150552|uniprotkb:Q2MA75|ensemblbacteria:AAC75796|ensemblbacteria:BAE76831	intact:EBI-1130209|uniprotkb:Q2MA74|ensemblbacteria:AAC75797|ensemblbacteria:BAE76832	psi-mi:cas2_ecoli(display_long)|uniprotkb:ygbF(gene name)|psi-mi:ygbF(display_short)|uniprotkb:cas2(gene name synonym)|uniprotkb:JW5438(locus name)|uniprotkb:b2754(locus name)	psi-mi:cas1_ecoli(display_long)|uniprotkb:ygbT(gene name)|psi-mi:ygbT(display_short)|uniprotkb:cas1(gene name synonym)|uniprotkb:JW2725(locus name)|uniprotkb:b2755(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nuñez et al. (2014)	pubmed:24793649|doi:10.1038/nsmb.2820|imex:IM-22701	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104775|imex:IM-22701-2|dip:DIP-196559E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417234.2|refseq:WP_001381369.1|dip:DIP-12109N|ensemblbacteria:AAC75796(transcript)|ensemblbacteria:b2754(gene)|ensemblbacteria:BAE76831(gene)|ensemblbacteria:BAE76831(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|interpro:IPR010152(CRISPR-associated protein, Cas2)|rcsb pdb:4MAK|rcsb pdb:4QDL|rcsb pdb:5DLJ|rcsb pdb:5DQT|rcsb pdb:5DQU|rcsb pdb:5DQZ|rcsb pdb:5DS4|rcsb pdb:5DS5|rcsb pdb:5DS6|rcsb pdb:5VVJ|rcsb pdb:5VVK|rcsb pdb:5VVL|rcsb pdb:5WFE|rcsb pdb:4P6I	refseq:WP_000220066.1|ensemblbacteria:AAC75797(transcript)|ensemblbacteria:b2755(gene)|ensemblbacteria:BAE76832(gene)|ensemblbacteria:BAE76832(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR002729(Protein of unknown function DUF48)|interpro:IPR019851|interpro:IPR033641|interpro:IPR042206|interpro:IPR042211|rcsb pdb:3NKD|rcsb pdb:3NKE|rcsb pdb:4P6I|rcsb pdb:4QDL|rcsb pdb:5DLJ|rcsb pdb:5DQT|rcsb pdb:5DQU|rcsb pdb:5DQZ|rcsb pdb:5DS4|rcsb pdb:5DS5|rcsb pdb:5DS6|rcsb pdb:5VVJ|rcsb pdb:5VVK|rcsb pdb:5VVL|rcsb pdb:5WFE|go:"GO:0043571"(maintenance of CRISPR repeat elements)|refseq:NP_417235.1|dip:DIP-12118N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:6EjHRdSrUgUHaAdrhkJ97lbVeNU83333	rogid:1bnu0y0OTtFF0EdSWcsdyw/+Of083333	rigid:ddXeNOrkPYLJpNx4aL8uRD5CiSM	false	ha tag:c-c	flag tag:c-c|mutation disrupting interaction strength:252-252	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q46896	uniprotkb:Q46896	intact:EBI-1130209|uniprotkb:Q2MA74|ensemblbacteria:AAC75797|ensemblbacteria:BAE76832	intact:EBI-1130209|uniprotkb:Q2MA74|ensemblbacteria:AAC75797|ensemblbacteria:BAE76832	psi-mi:cas1_ecoli(display_long)|uniprotkb:ygbT(gene name)|psi-mi:ygbT(display_short)|uniprotkb:cas1(gene name synonym)|uniprotkb:JW2725(locus name)|uniprotkb:b2755(locus name)	psi-mi:cas1_ecoli(display_long)|uniprotkb:ygbT(gene name)|psi-mi:ygbT(display_short)|uniprotkb:cas1(gene name synonym)|uniprotkb:JW2725(locus name)|uniprotkb:b2755(locus name)	psi-mi:"MI:0071"(molecular sieving)	Nuñez et al. (2014)	pubmed:24793649|doi:10.1038/nsmb.2820|imex:IM-22701	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104759|imex:IM-22701-1|dip:DIP-196560E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_000220066.1|ensemblbacteria:AAC75797(transcript)|ensemblbacteria:b2755(gene)|ensemblbacteria:BAE76832(gene)|ensemblbacteria:BAE76832(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR002729(Protein of unknown function DUF48)|interpro:IPR019851|interpro:IPR033641|interpro:IPR042206|interpro:IPR042211|rcsb pdb:3NKD|rcsb pdb:3NKE|rcsb pdb:4P6I|rcsb pdb:4QDL|rcsb pdb:5DLJ|rcsb pdb:5DQT|rcsb pdb:5DQU|rcsb pdb:5DQZ|rcsb pdb:5DS4|rcsb pdb:5DS5|rcsb pdb:5DS6|rcsb pdb:5VVJ|rcsb pdb:5VVK|rcsb pdb:5VVL|rcsb pdb:5WFE|go:"GO:0043571"(maintenance of CRISPR repeat elements)|refseq:NP_417235.1|dip:DIP-12118N	refseq:WP_000220066.1|ensemblbacteria:AAC75797(transcript)|ensemblbacteria:b2755(gene)|ensemblbacteria:BAE76832(gene)|ensemblbacteria:BAE76832(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR002729(Protein of unknown function DUF48)|interpro:IPR019851|interpro:IPR033641|interpro:IPR042206|interpro:IPR042211|rcsb pdb:3NKD|rcsb pdb:3NKE|rcsb pdb:4P6I|rcsb pdb:4QDL|rcsb pdb:5DLJ|rcsb pdb:5DQT|rcsb pdb:5DQU|rcsb pdb:5DQZ|rcsb pdb:5DS4|rcsb pdb:5DS5|rcsb pdb:5DS6|rcsb pdb:5VVJ|rcsb pdb:5VVK|rcsb pdb:5VVL|rcsb pdb:5WFE|go:"GO:0043571"(maintenance of CRISPR repeat elements)|refseq:NP_417235.1|dip:DIP-12118N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:1bnu0y0OTtFF0EdSWcsdyw/+Of083333	rogid:1bnu0y0OTtFF0EdSWcsdyw/+Of083333	rigid:O9qzJWOChY/E8DNOS2+E0tJGhwg	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P45956	uniprotkb:Q46896	intact:EBI-9150552|uniprotkb:Q2MA75|ensemblbacteria:AAC75796|ensemblbacteria:BAE76831	intact:EBI-1130209|uniprotkb:Q2MA74|ensemblbacteria:AAC75797|ensemblbacteria:BAE76832	psi-mi:cas2_ecoli(display_long)|uniprotkb:ygbF(gene name)|psi-mi:ygbF(display_short)|uniprotkb:cas2(gene name synonym)|uniprotkb:JW5438(locus name)|uniprotkb:b2754(locus name)	psi-mi:cas1_ecoli(display_long)|uniprotkb:ygbT(gene name)|psi-mi:ygbT(display_short)|uniprotkb:cas1(gene name synonym)|uniprotkb:JW2725(locus name)|uniprotkb:b2755(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Nuñez et al. (2014)	pubmed:24793649|doi:10.1038/nsmb.2820|imex:IM-22701	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104799|imex:IM-22701-3|dip:DIP-196559E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417234.2|refseq:WP_001381369.1|dip:DIP-12109N|ensemblbacteria:AAC75796(transcript)|ensemblbacteria:b2754(gene)|ensemblbacteria:BAE76831(gene)|ensemblbacteria:BAE76831(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|interpro:IPR010152(CRISPR-associated protein, Cas2)|rcsb pdb:4MAK|rcsb pdb:4QDL|rcsb pdb:5DLJ|rcsb pdb:5DQT|rcsb pdb:5DQU|rcsb pdb:5DQZ|rcsb pdb:5DS4|rcsb pdb:5DS5|rcsb pdb:5DS6|rcsb pdb:5VVJ|rcsb pdb:5VVK|rcsb pdb:5VVL|rcsb pdb:5WFE|rcsb pdb:4P6I	refseq:WP_000220066.1|ensemblbacteria:AAC75797(transcript)|ensemblbacteria:b2755(gene)|ensemblbacteria:BAE76832(gene)|ensemblbacteria:BAE76832(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR002729(Protein of unknown function DUF48)|interpro:IPR019851|interpro:IPR033641|interpro:IPR042206|interpro:IPR042211|rcsb pdb:3NKD|rcsb pdb:3NKE|rcsb pdb:4P6I|rcsb pdb:4QDL|rcsb pdb:5DLJ|rcsb pdb:5DQT|rcsb pdb:5DQU|rcsb pdb:5DQZ|rcsb pdb:5DS4|rcsb pdb:5DS5|rcsb pdb:5DS6|rcsb pdb:5VVJ|rcsb pdb:5VVK|rcsb pdb:5VVL|rcsb pdb:5WFE|go:"GO:0043571"(maintenance of CRISPR repeat elements)|refseq:NP_417235.1|dip:DIP-12118N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:6EjHRdSrUgUHaAdrhkJ97lbVeNU83333	rogid:1bnu0y0OTtFF0EdSWcsdyw/+Of083333	rigid:ddXeNOrkPYLJpNx4aL8uRD5CiSM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P45956	uniprotkb:Q46896	intact:EBI-9150552|uniprotkb:Q2MA75|ensemblbacteria:AAC75796|ensemblbacteria:BAE76831	intact:EBI-1130209|uniprotkb:Q2MA74|ensemblbacteria:AAC75797|ensemblbacteria:BAE76832	psi-mi:cas2_ecoli(display_long)|uniprotkb:ygbF(gene name)|psi-mi:ygbF(display_short)|uniprotkb:cas2(gene name synonym)|uniprotkb:JW5438(locus name)|uniprotkb:b2754(locus name)	psi-mi:cas1_ecoli(display_long)|uniprotkb:ygbT(gene name)|psi-mi:ygbT(display_short)|uniprotkb:cas1(gene name synonym)|uniprotkb:JW2725(locus name)|uniprotkb:b2755(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nuñez et al. (2014)	pubmed:24793649|doi:10.1038/nsmb.2820|imex:IM-22701	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104869|imex:IM-22701-7|dip:DIP-196559E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417234.2|refseq:WP_001381369.1|dip:DIP-12109N|ensemblbacteria:AAC75796(transcript)|ensemblbacteria:b2754(gene)|ensemblbacteria:BAE76831(gene)|ensemblbacteria:BAE76831(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|interpro:IPR010152(CRISPR-associated protein, Cas2)|rcsb pdb:4MAK|rcsb pdb:4QDL|rcsb pdb:5DLJ|rcsb pdb:5DQT|rcsb pdb:5DQU|rcsb pdb:5DQZ|rcsb pdb:5DS4|rcsb pdb:5DS5|rcsb pdb:5DS6|rcsb pdb:5VVJ|rcsb pdb:5VVK|rcsb pdb:5VVL|rcsb pdb:5WFE|rcsb pdb:4P6I	refseq:WP_000220066.1|ensemblbacteria:AAC75797(transcript)|ensemblbacteria:b2755(gene)|ensemblbacteria:BAE76832(gene)|ensemblbacteria:BAE76832(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR002729(Protein of unknown function DUF48)|interpro:IPR019851|interpro:IPR033641|interpro:IPR042206|interpro:IPR042211|rcsb pdb:3NKD|rcsb pdb:3NKE|rcsb pdb:4P6I|rcsb pdb:4QDL|rcsb pdb:5DLJ|rcsb pdb:5DQT|rcsb pdb:5DQU|rcsb pdb:5DQZ|rcsb pdb:5DS4|rcsb pdb:5DS5|rcsb pdb:5DS6|rcsb pdb:5VVJ|rcsb pdb:5VVK|rcsb pdb:5VVL|rcsb pdb:5WFE|go:"GO:0043571"(maintenance of CRISPR repeat elements)|refseq:NP_417235.1|dip:DIP-12118N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:6EjHRdSrUgUHaAdrhkJ97lbVeNU83333	rogid:1bnu0y0OTtFF0EdSWcsdyw/+Of083333	rigid:ddXeNOrkPYLJpNx4aL8uRD5CiSM	false	ha tag:c-c|necessary binding region:74-94	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P45956	uniprotkb:P45956	intact:EBI-9150552|uniprotkb:Q2MA75|ensemblbacteria:AAC75796|ensemblbacteria:BAE76831	intact:EBI-9150552|uniprotkb:Q2MA75|ensemblbacteria:AAC75796|ensemblbacteria:BAE76831	psi-mi:cas2_ecoli(display_long)|uniprotkb:ygbF(gene name)|psi-mi:ygbF(display_short)|uniprotkb:cas2(gene name synonym)|uniprotkb:JW5438(locus name)|uniprotkb:b2754(locus name)	psi-mi:cas2_ecoli(display_long)|uniprotkb:ygbF(gene name)|psi-mi:ygbF(display_short)|uniprotkb:cas2(gene name synonym)|uniprotkb:JW5438(locus name)|uniprotkb:b2754(locus name)	psi-mi:"MI:0028"(cosedimentation in solution)	Nuñez et al. (2014)	pubmed:24793649|doi:10.1038/nsmb.2820|imex:IM-22701	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104892|imex:IM-22701-8|dip:DIP-196561E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417234.2|refseq:WP_001381369.1|dip:DIP-12109N|ensemblbacteria:AAC75796(transcript)|ensemblbacteria:b2754(gene)|ensemblbacteria:BAE76831(gene)|ensemblbacteria:BAE76831(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|interpro:IPR010152(CRISPR-associated protein, Cas2)|rcsb pdb:4MAK|rcsb pdb:4QDL|rcsb pdb:5DLJ|rcsb pdb:5DQT|rcsb pdb:5DQU|rcsb pdb:5DQZ|rcsb pdb:5DS4|rcsb pdb:5DS5|rcsb pdb:5DS6|rcsb pdb:5VVJ|rcsb pdb:5VVK|rcsb pdb:5VVL|rcsb pdb:5WFE|rcsb pdb:4P6I	refseq:NP_417234.2|refseq:WP_001381369.1|dip:DIP-12109N|ensemblbacteria:AAC75796(transcript)|ensemblbacteria:b2754(gene)|ensemblbacteria:BAE76831(gene)|ensemblbacteria:BAE76831(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|interpro:IPR010152(CRISPR-associated protein, Cas2)|rcsb pdb:4MAK|rcsb pdb:4QDL|rcsb pdb:5DLJ|rcsb pdb:5DQT|rcsb pdb:5DQU|rcsb pdb:5DQZ|rcsb pdb:5DS4|rcsb pdb:5DS5|rcsb pdb:5DS6|rcsb pdb:5VVJ|rcsb pdb:5VVK|rcsb pdb:5VVL|rcsb pdb:5WFE|rcsb pdb:4P6I	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:6EjHRdSrUgUHaAdrhkJ97lbVeNU83333	rogid:6EjHRdSrUgUHaAdrhkJ97lbVeNU83333	rigid:URq3qDVNDtLZk0a4QhuUGnFUuO4	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q46896	uniprotkb:Q46896	intact:EBI-1130209|uniprotkb:Q2MA74|ensemblbacteria:AAC75797|ensemblbacteria:BAE76832	intact:EBI-1130209|uniprotkb:Q2MA74|ensemblbacteria:AAC75797|ensemblbacteria:BAE76832	psi-mi:cas1_ecoli(display_long)|uniprotkb:ygbT(gene name)|psi-mi:ygbT(display_short)|uniprotkb:cas1(gene name synonym)|uniprotkb:JW2725(locus name)|uniprotkb:b2755(locus name)	psi-mi:cas1_ecoli(display_long)|uniprotkb:ygbT(gene name)|psi-mi:ygbT(display_short)|uniprotkb:cas1(gene name synonym)|uniprotkb:JW2725(locus name)|uniprotkb:b2755(locus name)	psi-mi:"MI:0028"(cosedimentation in solution)	Nuñez et al. (2014)	pubmed:24793649|doi:10.1038/nsmb.2820|imex:IM-22701	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104851|imex:IM-22701-6|dip:DIP-196560E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_000220066.1|ensemblbacteria:AAC75797(transcript)|ensemblbacteria:b2755(gene)|ensemblbacteria:BAE76832(gene)|ensemblbacteria:BAE76832(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR002729(Protein of unknown function DUF48)|interpro:IPR019851|interpro:IPR033641|interpro:IPR042206|interpro:IPR042211|rcsb pdb:3NKD|rcsb pdb:3NKE|rcsb pdb:4P6I|rcsb pdb:4QDL|rcsb pdb:5DLJ|rcsb pdb:5DQT|rcsb pdb:5DQU|rcsb pdb:5DQZ|rcsb pdb:5DS4|rcsb pdb:5DS5|rcsb pdb:5DS6|rcsb pdb:5VVJ|rcsb pdb:5VVK|rcsb pdb:5VVL|rcsb pdb:5WFE|go:"GO:0043571"(maintenance of CRISPR repeat elements)|refseq:NP_417235.1|dip:DIP-12118N	refseq:WP_000220066.1|ensemblbacteria:AAC75797(transcript)|ensemblbacteria:b2755(gene)|ensemblbacteria:BAE76832(gene)|ensemblbacteria:BAE76832(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR002729(Protein of unknown function DUF48)|interpro:IPR019851|interpro:IPR033641|interpro:IPR042206|interpro:IPR042211|rcsb pdb:3NKD|rcsb pdb:3NKE|rcsb pdb:4P6I|rcsb pdb:4QDL|rcsb pdb:5DLJ|rcsb pdb:5DQT|rcsb pdb:5DQU|rcsb pdb:5DQZ|rcsb pdb:5DS4|rcsb pdb:5DS5|rcsb pdb:5DS6|rcsb pdb:5VVJ|rcsb pdb:5VVK|rcsb pdb:5VVL|rcsb pdb:5WFE|go:"GO:0043571"(maintenance of CRISPR repeat elements)|refseq:NP_417235.1|dip:DIP-12118N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:1bnu0y0OTtFF0EdSWcsdyw/+Of083333	rogid:1bnu0y0OTtFF0EdSWcsdyw/+Of083333	rigid:O9qzJWOChY/E8DNOS2+E0tJGhwg	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P45956	uniprotkb:Q46896	intact:EBI-9150552|uniprotkb:Q2MA75|ensemblbacteria:AAC75796|ensemblbacteria:BAE76831	intact:EBI-1130209|uniprotkb:Q2MA74|ensemblbacteria:AAC75797|ensemblbacteria:BAE76832	psi-mi:cas2_ecoli(display_long)|uniprotkb:ygbF(gene name)|psi-mi:ygbF(display_short)|uniprotkb:cas2(gene name synonym)|uniprotkb:JW5438(locus name)|uniprotkb:b2754(locus name)	psi-mi:cas1_ecoli(display_long)|uniprotkb:ygbT(gene name)|psi-mi:ygbT(display_short)|uniprotkb:cas1(gene name synonym)|uniprotkb:JW2725(locus name)|uniprotkb:b2755(locus name)	psi-mi:"MI:0071"(molecular sieving)	Nuñez et al. (2014)	pubmed:24793649|doi:10.1038/nsmb.2820|imex:IM-22701	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104834|imex:IM-22701-5|dip:DIP-196559E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417234.2|refseq:WP_001381369.1|dip:DIP-12109N|ensemblbacteria:AAC75796(transcript)|ensemblbacteria:b2754(gene)|ensemblbacteria:BAE76831(gene)|ensemblbacteria:BAE76831(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|interpro:IPR010152(CRISPR-associated protein, Cas2)|rcsb pdb:4MAK|rcsb pdb:4QDL|rcsb pdb:5DLJ|rcsb pdb:5DQT|rcsb pdb:5DQU|rcsb pdb:5DQZ|rcsb pdb:5DS4|rcsb pdb:5DS5|rcsb pdb:5DS6|rcsb pdb:5VVJ|rcsb pdb:5VVK|rcsb pdb:5VVL|rcsb pdb:5WFE|rcsb pdb:4P6I	refseq:WP_000220066.1|ensemblbacteria:AAC75797(transcript)|ensemblbacteria:b2755(gene)|ensemblbacteria:BAE76832(gene)|ensemblbacteria:BAE76832(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR002729(Protein of unknown function DUF48)|interpro:IPR019851|interpro:IPR033641|interpro:IPR042206|interpro:IPR042211|rcsb pdb:3NKD|rcsb pdb:3NKE|rcsb pdb:4P6I|rcsb pdb:4QDL|rcsb pdb:5DLJ|rcsb pdb:5DQT|rcsb pdb:5DQU|rcsb pdb:5DQZ|rcsb pdb:5DS4|rcsb pdb:5DS5|rcsb pdb:5DS6|rcsb pdb:5VVJ|rcsb pdb:5VVK|rcsb pdb:5VVL|rcsb pdb:5WFE|go:"GO:0043571"(maintenance of CRISPR repeat elements)|refseq:NP_417235.1|dip:DIP-12118N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:6EjHRdSrUgUHaAdrhkJ97lbVeNU83333	rogid:1bnu0y0OTtFF0EdSWcsdyw/+Of083333	rigid:ddXeNOrkPYLJpNx4aL8uRD5CiSM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P45956	uniprotkb:Q46896	intact:EBI-9150552|uniprotkb:Q2MA75|ensemblbacteria:AAC75796|ensemblbacteria:BAE76831	intact:EBI-1130209|uniprotkb:Q2MA74|ensemblbacteria:AAC75797|ensemblbacteria:BAE76832	psi-mi:cas2_ecoli(display_long)|uniprotkb:ygbF(gene name)|psi-mi:ygbF(display_short)|uniprotkb:cas2(gene name synonym)|uniprotkb:JW5438(locus name)|uniprotkb:b2754(locus name)	psi-mi:cas1_ecoli(display_long)|uniprotkb:ygbT(gene name)|psi-mi:ygbT(display_short)|uniprotkb:cas1(gene name synonym)|uniprotkb:JW2725(locus name)|uniprotkb:b2755(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Nuñez et al. (2014)	pubmed:24793649|doi:10.1038/nsmb.2820|imex:IM-22701	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104817|imex:IM-22701-4|dip:DIP-196559E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417234.2|refseq:WP_001381369.1|dip:DIP-12109N|ensemblbacteria:AAC75796(transcript)|ensemblbacteria:b2754(gene)|ensemblbacteria:BAE76831(gene)|ensemblbacteria:BAE76831(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|interpro:IPR010152(CRISPR-associated protein, Cas2)|rcsb pdb:4MAK|rcsb pdb:4QDL|rcsb pdb:5DLJ|rcsb pdb:5DQT|rcsb pdb:5DQU|rcsb pdb:5DQZ|rcsb pdb:5DS4|rcsb pdb:5DS5|rcsb pdb:5DS6|rcsb pdb:5VVJ|rcsb pdb:5VVK|rcsb pdb:5VVL|rcsb pdb:5WFE|rcsb pdb:4P6I	refseq:WP_000220066.1|ensemblbacteria:AAC75797(transcript)|ensemblbacteria:b2755(gene)|ensemblbacteria:BAE76832(gene)|ensemblbacteria:BAE76832(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR002729(Protein of unknown function DUF48)|interpro:IPR019851|interpro:IPR033641|interpro:IPR042206|interpro:IPR042211|rcsb pdb:3NKD|rcsb pdb:3NKE|rcsb pdb:4P6I|rcsb pdb:4QDL|rcsb pdb:5DLJ|rcsb pdb:5DQT|rcsb pdb:5DQU|rcsb pdb:5DQZ|rcsb pdb:5DS4|rcsb pdb:5DS5|rcsb pdb:5DS6|rcsb pdb:5VVJ|rcsb pdb:5VVK|rcsb pdb:5VVL|rcsb pdb:5WFE|go:"GO:0043571"(maintenance of CRISPR repeat elements)|refseq:NP_417235.1|dip:DIP-12118N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:6EjHRdSrUgUHaAdrhkJ97lbVeNU83333	rogid:1bnu0y0OTtFF0EdSWcsdyw/+Of083333	rigid:ddXeNOrkPYLJpNx4aL8uRD5CiSM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P45956	uniprotkb:Q46896	intact:EBI-9150552|uniprotkb:Q2MA75|ensemblbacteria:AAC75796|ensemblbacteria:BAE76831	intact:EBI-1130209|uniprotkb:Q2MA74|ensemblbacteria:AAC75797|ensemblbacteria:BAE76832	psi-mi:cas2_ecoli(display_long)|uniprotkb:ygbF(gene name)|psi-mi:ygbF(display_short)|uniprotkb:cas2(gene name synonym)|uniprotkb:JW5438(locus name)|uniprotkb:b2754(locus name)	psi-mi:cas1_ecoli(display_long)|uniprotkb:ygbT(gene name)|psi-mi:ygbT(display_short)|uniprotkb:cas1(gene name synonym)|uniprotkb:JW2725(locus name)|uniprotkb:b2755(locus name)	psi-mi:"MI:0028"(cosedimentation in solution)	Nuñez et al. (2014)	pubmed:24793649|doi:10.1038/nsmb.2820|imex:IM-22701	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104908|imex:IM-22701-9|dip:DIP-196559E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417234.2|refseq:WP_001381369.1|dip:DIP-12109N|ensemblbacteria:AAC75796(transcript)|ensemblbacteria:b2754(gene)|ensemblbacteria:BAE76831(gene)|ensemblbacteria:BAE76831(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|interpro:IPR010152(CRISPR-associated protein, Cas2)|rcsb pdb:4MAK|rcsb pdb:4QDL|rcsb pdb:5DLJ|rcsb pdb:5DQT|rcsb pdb:5DQU|rcsb pdb:5DQZ|rcsb pdb:5DS4|rcsb pdb:5DS5|rcsb pdb:5DS6|rcsb pdb:5VVJ|rcsb pdb:5VVK|rcsb pdb:5VVL|rcsb pdb:5WFE|rcsb pdb:4P6I	refseq:WP_000220066.1|ensemblbacteria:AAC75797(transcript)|ensemblbacteria:b2755(gene)|ensemblbacteria:BAE76832(gene)|ensemblbacteria:BAE76832(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR002729(Protein of unknown function DUF48)|interpro:IPR019851|interpro:IPR033641|interpro:IPR042206|interpro:IPR042211|rcsb pdb:3NKD|rcsb pdb:3NKE|rcsb pdb:4P6I|rcsb pdb:4QDL|rcsb pdb:5DLJ|rcsb pdb:5DQT|rcsb pdb:5DQU|rcsb pdb:5DQZ|rcsb pdb:5DS4|rcsb pdb:5DS5|rcsb pdb:5DS6|rcsb pdb:5VVJ|rcsb pdb:5VVK|rcsb pdb:5VVL|rcsb pdb:5WFE|go:"GO:0043571"(maintenance of CRISPR repeat elements)|refseq:NP_417235.1|dip:DIP-12118N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:6EjHRdSrUgUHaAdrhkJ97lbVeNU83333	rogid:1bnu0y0OTtFF0EdSWcsdyw/+Of083333	rigid:ddXeNOrkPYLJpNx4aL8uRD5CiSM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)