#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:B0BLW3	uniprotkb:B0BLW3	intact:EBI-7425077|intact:MINT-8297617|uniprotkb:F6US71	intact:EBI-7425077|intact:MINT-8297617|uniprotkb:F6US71	psi-mi:lgr4_xentr(display_long)|uniprotkb:lgr4(gene name)|psi-mi:lgr4(display_short)	psi-mi:lgr4_xentr(display_long)|uniprotkb:lgr4(gene name)|psi-mi:lgr4(display_short)	psi-mi:"MI:0071"(molecular sieving)	Xu et al. (2013)	pubmed:23891289|doi:10.1016/j.str.2013.07.001|imex:IM-21897	taxid:8364(xentr)|taxid:8364("Xenopus tropicalis (Western clawed frog)")	taxid:8364(xentr)|taxid:8364("Xenopus tropicalis (Western clawed frog)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16066300|imex:IM-21897-1|dip:DIP-192437E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001119970.1|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016500"(protein-hormone receptor activity)|go:"GO:0030282"(bone mineralization)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0046849"(bone remodeling)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002131(Glycoprotein hormone receptor)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR032675|rcsb pdb:4LI1|rcsb pdb:4LI2|go:"GO:0001818"(negative regulation of cytokine production)|dip:DIP-60560N	refseq:NP_001119970.1|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016500"(protein-hormone receptor activity)|go:"GO:0030282"(bone mineralization)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0046849"(bone remodeling)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002131(Glycoprotein hormone receptor)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR032675|rcsb pdb:4LI1|rcsb pdb:4LI2|go:"GO:0001818"(negative regulation of cytokine production)|dip:DIP-60560N	psi-mi:"MI:0465"(dip)	comment:mint	comment:mint	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:YiEUogAukuaTsNPSiaALi2LQK0U8364	rogid:YiEUogAukuaTsNPSiaALi2LQK0U8364	rigid:+EXvBqbWegmo4YbN2rqqKcsPl9I	false	sufficient binding region:24-455	sufficient binding region:24-455	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:B0BLW3	uniprotkb:Q2MKA7	intact:EBI-7425077|intact:MINT-8297617|uniprotkb:F6US71	intact:EBI-10045219|uniprotkb:A2A420|uniprotkb:Q0H8S6|uniprotkb:Q14C72|uniprotkb:Q5T0F2|uniprotkb:Q8N7L5|ensembl:ENSP00000348944|ensembl:ENSP00000383846	psi-mi:lgr4_xentr(display_long)|uniprotkb:lgr4(gene name)|psi-mi:lgr4(display_short)	psi-mi:rspo1_human(display_long)|uniprotkb:RSPO1(gene name)|psi-mi:RSPO1(display_short)|uniprotkb:Roof plate-specific spondin-1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Xu et al. (2013)	pubmed:23891289|doi:10.1016/j.str.2013.07.001|imex:IM-21897	taxid:8364(xentr)|taxid:8364("Xenopus tropicalis (Western clawed frog)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16066318|imex:IM-21897-2|dip:DIP-192438E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001119970.1|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016500"(protein-hormone receptor activity)|go:"GO:0030282"(bone mineralization)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0046849"(bone remodeling)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002131(Glycoprotein hormone receptor)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR032675|rcsb pdb:4LI1|rcsb pdb:4LI2|go:"GO:0001818"(negative regulation of cytokine production)|dip:DIP-60560N	refseq:NP_001033722.1|refseq:NP_001229837.1|refseq:NP_001229838.1|refseq:NP_001229839.1|refseq:XP_006710646.1|ensembl:ENSG00000169218(gene)|ensembl:ENST00000356545(transcript)|ensembl:ENST00000401068(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0008201"(heparin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR006212(Furin-like repeat)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR036383|interpro:IPR042991|interpro:IPR043601|rcsb pdb:4BSO|rcsb pdb:4BSP|rcsb pdb:4BSR|rcsb pdb:4BSS|rcsb pdb:4BST|rcsb pdb:4BSU|rcsb pdb:4CDK|rcsb pdb:4KNG|rcsb pdb:4KT1|rcsb pdb:4LI2|rcsb pdb:4QXF|reactome:R-HSA-4641263|dip:DIP-59895N	psi-mi:"MI:0465"(dip)	comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:YiEUogAukuaTsNPSiaALi2LQK0U8364	rogid:+NBHcmOpvY9I2ubG2O8bLiGzmUk9606	rigid:5MhQmtBOGYw8dYyZ4LNW3wzvjf4	false	sufficient binding region:24-455	sufficient binding region:33-144	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:B0BLW3	uniprotkb:B0BLW3	intact:EBI-7425077|intact:MINT-8297617|uniprotkb:F6US71	intact:EBI-7425077|intact:MINT-8297617|uniprotkb:F6US71	psi-mi:lgr4_xentr(display_long)|uniprotkb:lgr4(gene name)|psi-mi:lgr4(display_short)	psi-mi:lgr4_xentr(display_long)|uniprotkb:lgr4(gene name)|psi-mi:lgr4(display_short)	psi-mi:"MI:0038"(dynamic light scattering)	Xu et al. (2013)	pubmed:23891289|doi:10.1016/j.str.2013.07.001|imex:IM-21897	taxid:8364(xentr)|taxid:8364("Xenopus tropicalis (Western clawed frog)")	taxid:8364(xentr)|taxid:8364("Xenopus tropicalis (Western clawed frog)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16066339|imex:IM-21897-3|dip:DIP-192437E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001119970.1|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016500"(protein-hormone receptor activity)|go:"GO:0030282"(bone mineralization)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0046849"(bone remodeling)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002131(Glycoprotein hormone receptor)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR032675|rcsb pdb:4LI1|rcsb pdb:4LI2|go:"GO:0001818"(negative regulation of cytokine production)|dip:DIP-60560N	refseq:NP_001119970.1|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016500"(protein-hormone receptor activity)|go:"GO:0030282"(bone mineralization)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0046849"(bone remodeling)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002131(Glycoprotein hormone receptor)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR032675|rcsb pdb:4LI1|rcsb pdb:4LI2|go:"GO:0001818"(negative regulation of cytokine production)|dip:DIP-60560N	psi-mi:"MI:0465"(dip)	comment:mint	comment:mint	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:YiEUogAukuaTsNPSiaALi2LQK0U8364	rogid:YiEUogAukuaTsNPSiaALi2LQK0U8364	rigid:+EXvBqbWegmo4YbN2rqqKcsPl9I	false	sufficient binding region:24-455	sufficient binding region:24-455	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:B0BLW3	uniprotkb:Q2MKA7	intact:EBI-7425077|intact:MINT-8297617|uniprotkb:F6US71	intact:EBI-10045219|uniprotkb:A2A420|uniprotkb:Q0H8S6|uniprotkb:Q14C72|uniprotkb:Q5T0F2|uniprotkb:Q8N7L5|ensembl:ENSP00000348944|ensembl:ENSP00000383846	psi-mi:lgr4_xentr(display_long)|uniprotkb:lgr4(gene name)|psi-mi:lgr4(display_short)	psi-mi:rspo1_human(display_long)|uniprotkb:RSPO1(gene name)|psi-mi:RSPO1(display_short)|uniprotkb:Roof plate-specific spondin-1(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Xu et al. (2013)	pubmed:23891289|doi:10.1016/j.str.2013.07.001|imex:IM-21897	taxid:8364(xentr)|taxid:8364("Xenopus tropicalis (Western clawed frog)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16066358|imex:IM-21897-4|dip:DIP-192438E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001119970.1|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016500"(protein-hormone receptor activity)|go:"GO:0030282"(bone mineralization)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0046849"(bone remodeling)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002131(Glycoprotein hormone receptor)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR032675|rcsb pdb:4LI1|rcsb pdb:4LI2|go:"GO:0001818"(negative regulation of cytokine production)|dip:DIP-60560N	refseq:NP_001033722.1|refseq:NP_001229837.1|refseq:NP_001229838.1|refseq:NP_001229839.1|refseq:XP_006710646.1|ensembl:ENSG00000169218(gene)|ensembl:ENST00000356545(transcript)|ensembl:ENST00000401068(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0008201"(heparin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR006212(Furin-like repeat)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR036383|interpro:IPR042991|interpro:IPR043601|rcsb pdb:4BSO|rcsb pdb:4BSP|rcsb pdb:4BSR|rcsb pdb:4BSS|rcsb pdb:4BST|rcsb pdb:4BSU|rcsb pdb:4CDK|rcsb pdb:4KNG|rcsb pdb:4KT1|rcsb pdb:4LI2|rcsb pdb:4QXF|reactome:R-HSA-4641263|dip:DIP-59895N	psi-mi:"MI:0465"(dip)	comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:YiEUogAukuaTsNPSiaALi2LQK0U8364	rogid:+NBHcmOpvY9I2ubG2O8bLiGzmUk9606	rigid:5MhQmtBOGYw8dYyZ4LNW3wzvjf4	false	sufficient binding region:24-455	sufficient binding region:33-144	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:B0BLW3	uniprotkb:B0BLW3	intact:EBI-7425077|intact:MINT-8297617|uniprotkb:F6US71	intact:EBI-7425077|intact:MINT-8297617|uniprotkb:F6US71	psi-mi:lgr4_xentr(display_long)|uniprotkb:lgr4(gene name)|psi-mi:lgr4(display_short)	psi-mi:lgr4_xentr(display_long)|uniprotkb:lgr4(gene name)|psi-mi:lgr4(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Xu et al. (2013)	pubmed:23891289|doi:10.1016/j.str.2013.07.001|imex:IM-21897	taxid:8364(xentr)|taxid:8364("Xenopus tropicalis (Western clawed frog)")	taxid:8364(xentr)|taxid:8364("Xenopus tropicalis (Western clawed frog)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16066380|imex:IM-21897-5|dip:DIP-192437E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001119970.1|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016500"(protein-hormone receptor activity)|go:"GO:0030282"(bone mineralization)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0046849"(bone remodeling)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002131(Glycoprotein hormone receptor)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR032675|rcsb pdb:4LI1|rcsb pdb:4LI2|go:"GO:0001818"(negative regulation of cytokine production)|dip:DIP-60560N	refseq:NP_001119970.1|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016500"(protein-hormone receptor activity)|go:"GO:0030282"(bone mineralization)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0046849"(bone remodeling)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002131(Glycoprotein hormone receptor)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR032675|rcsb pdb:4LI1|rcsb pdb:4LI2|go:"GO:0001818"(negative regulation of cytokine production)|dip:DIP-60560N	psi-mi:"MI:0465"(dip)	comment:mint	comment:mint	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:YiEUogAukuaTsNPSiaALi2LQK0U8364	rogid:YiEUogAukuaTsNPSiaALi2LQK0U8364	rigid:+EXvBqbWegmo4YbN2rqqKcsPl9I	false	sufficient binding region:24-455	sufficient binding region:24-455	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)