#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9R016 uniprotkb:Q3UP24 intact:EBI-15944130|ensembl:ENSMUSP00000058611|uniprotkb:Q8CGT2|uniprotkb:O09121|uniprotkb:O09122|uniprotkb:P81703|uniprotkb:Q9R029 intact:EBI-16006652|ensembl:ENSMUSP00000059637|uniprotkb:Q3TAU8 psi-mi:bir1e_mouse(display_long)|uniprotkb:Naip5(gene name)|psi-mi:Naip5(display_short)|uniprotkb:Birc1e(gene name synonym)|uniprotkb:Naip-rs3(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 5(gene name synonym) psi-mi:nlrc4_mouse(display_long)|uniprotkb:Nlrc4(gene name)|psi-mi:Nlrc4(display_short)|uniprotkb:Card12(gene name synonym)|uniprotkb:Ipaf(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Hu et al. (2013) pubmed:23765277|doi:10.1126/science.1236381|imex:IM-24819 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16061098|imex:IM-24819-1|dip:DIP-199798E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000071203(gene)|ensembl:ENSMUST00000049789(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|rcsb pdb:5YUD|rcsb pdb:6B5B|refseq:XP_011242930.1|refseq:XP_017170904.1|dip:DIP-59148N|refseq:NP_035000.2 interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR040535|interpro:IPR042220|rcsb pdb:3JBL|rcsb pdb:4KXF|rcsb pdb:5AJ2|rcsb pdb:6B5B|interpro:IPR007111(NACHT nucleoside triphosphatase)|ensembl:ENSMUSG00000039193(gene)|ensembl:ENSMUST00000052124(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0089720"(caspase binding)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|refseq:NP_001028539.1|refseq:XP_006524409.1|refseq:XP_017172979.1|refseq:XP_017172980.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2018/04/30 rogid:yNnApOdrkulKaMVJOTBVq+0lB3E10090 rogid:EwJUZJSasbk43tsDLlfJqxC2oec10090 rigid:R9fGjgZ0oGOSQSlwxxlRtvYjH9w false myc tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)