#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P21213 uniprotkb:P21213 intact:EBI-916828|uniprotkb:Q5EBB8|ensembl:ENSRNOP00000006971 intact:EBI-916828|uniprotkb:Q5EBB8|ensembl:ENSRNOP00000006971 psi-mi:huth_rat(display_long)|uniprotkb:Hal(gene name)|psi-mi:Hal(display_short)|uniprotkb:Huth(gene name synonym) psi-mi:huth_rat(display_long)|uniprotkb:Hal(gene name)|psi-mi:Hal(display_short)|uniprotkb:Huth(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Zhang et al. (2013) pubmed:23643951|doi:10.1016/j.str.2013.04.004|imex:IM-21030 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16056935|imex:IM-21030-1|dip:DIP-190647E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:68363|refseq:NP_058855.1|dip:DIP-37290N|ensembl:ENSRNOG00000004502(gene)|ensembl:ENSRNOT00000006971(transcript)|go:"GO:0004397"(histidine ammonia-lyase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006547"(histidine metabolic process)|go:"GO:0006548"(histidine catabolic process)|go:"GO:0016841"(ammonia-lyase activity)|go:"GO:0019556"(histidine catabolic process to glutamate and formamide)|go:"GO:0019557"(histidine catabolic process to glutamate and formate)|interpro:IPR001106(Phenylalanine/histidine ammonia-lyase)|interpro:IPR005921(Histidine ammonia-lyase)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR021922|interpro:IPR022313|interpro:IPR024083|reactome:R-RNO-70921 rgd:68363|refseq:NP_058855.1|dip:DIP-37290N|ensembl:ENSRNOG00000004502(gene)|ensembl:ENSRNOT00000006971(transcript)|go:"GO:0004397"(histidine ammonia-lyase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006547"(histidine metabolic process)|go:"GO:0006548"(histidine catabolic process)|go:"GO:0016841"(ammonia-lyase activity)|go:"GO:0019556"(histidine catabolic process to glutamate and formamide)|go:"GO:0019557"(histidine catabolic process to glutamate and formate)|interpro:IPR001106(Phenylalanine/histidine ammonia-lyase)|interpro:IPR005921(Histidine ammonia-lyase)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR021922|interpro:IPR022313|interpro:IPR024083|reactome:R-RNO-70921 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:2551c93IPKtbF1db9g7R8K8xERc10116 rogid:2551c93IPKtbF1db9g7R8K8xERc10116 rigid:EYyhwVFAR/3HK58aSdRu8K/z34A false sufficient binding region:2-89 sufficient binding region:2-89 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z340 uniprotkb:Q9Z340 intact:EBI-349441|ensembl:ENSRNOP00000048964 intact:EBI-349441|ensembl:ENSRNOP00000048964 psi-mi:pard3_rat(display_long)|uniprotkb:Pard3(gene name)|psi-mi:Pard3(display_short)|uniprotkb:Par3(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:Atypical PKC-specific-binding protein(gene name synonym) psi-mi:pard3_rat(display_long)|uniprotkb:Pard3(gene name)|psi-mi:Pard3(display_short)|uniprotkb:Par3(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:Atypical PKC-specific-binding protein(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Zhang et al. (2013) pubmed:23643951|doi:10.1016/j.str.2013.04.004|imex:IM-21030 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16056953|imex:IM-21030-2|dip:DIP-190646E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620374|refseq:NP_112514.1|ensembl:ENSRNOG00000032437(gene)|ensembl:ENSRNOT00000042623(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003383"(apical constriction)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0008104"(protein localization)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045177"(apical part of cell)|go:"GO:0005912"(adherens junction)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|rcsb pdb:2K1Z|rcsb pdb:2K20|rcsb pdb:2NS5|rcsb pdb:2OGP|rcsb pdb:3ZEE|rcsb pdb:4DC2|rcsb pdb:4I6P|rcsb pdb:6JUE|reactome:R-RNO-2173791|reactome:R-RNO-420029|dip:DIP-33271N rgd:620374|refseq:NP_112514.1|ensembl:ENSRNOG00000032437(gene)|ensembl:ENSRNOT00000042623(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003383"(apical constriction)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0008104"(protein localization)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045177"(apical part of cell)|go:"GO:0005912"(adherens junction)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|rcsb pdb:2K1Z|rcsb pdb:2K20|rcsb pdb:2NS5|rcsb pdb:2OGP|rcsb pdb:3ZEE|rcsb pdb:4DC2|rcsb pdb:4I6P|rcsb pdb:6JUE|reactome:R-RNO-2173791|reactome:R-RNO-420029|dip:DIP-33271N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:pCIhxZdK3JRmJvgDmVgEtDI7fjc10116 rogid:pCIhxZdK3JRmJvgDmVgEtDI7fjc10116 rigid:y+GHeuk1n3HWQAt3LrigwIRPtf8 false sufficient binding region:2-83 sufficient binding region:2-83 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z340 uniprotkb:Q9Z340 intact:EBI-349441|ensembl:ENSRNOP00000048964 intact:EBI-349441|ensembl:ENSRNOP00000048964 psi-mi:pard3_rat(display_long)|uniprotkb:Pard3(gene name)|psi-mi:Pard3(display_short)|uniprotkb:Par3(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:Atypical PKC-specific-binding protein(gene name synonym) psi-mi:pard3_rat(display_long)|uniprotkb:Pard3(gene name)|psi-mi:Pard3(display_short)|uniprotkb:Par3(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:Atypical PKC-specific-binding protein(gene name synonym) psi-mi:"MI:0872"(atomic force microscopy) Zhang et al. (2013) pubmed:23643951|doi:10.1016/j.str.2013.04.004|imex:IM-21030 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16056971|imex:IM-21030-3|dip:DIP-190646E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620374|refseq:NP_112514.1|ensembl:ENSRNOG00000032437(gene)|ensembl:ENSRNOT00000042623(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003383"(apical constriction)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0008104"(protein localization)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045177"(apical part of cell)|go:"GO:0005912"(adherens junction)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|rcsb pdb:2K1Z|rcsb pdb:2K20|rcsb pdb:2NS5|rcsb pdb:2OGP|rcsb pdb:3ZEE|rcsb pdb:4DC2|rcsb pdb:4I6P|rcsb pdb:6JUE|reactome:R-RNO-2173791|reactome:R-RNO-420029|dip:DIP-33271N rgd:620374|refseq:NP_112514.1|ensembl:ENSRNOG00000032437(gene)|ensembl:ENSRNOT00000042623(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003383"(apical constriction)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0008104"(protein localization)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045177"(apical part of cell)|go:"GO:0005912"(adherens junction)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|rcsb pdb:2K1Z|rcsb pdb:2K20|rcsb pdb:2NS5|rcsb pdb:2OGP|rcsb pdb:3ZEE|rcsb pdb:4DC2|rcsb pdb:4I6P|rcsb pdb:6JUE|reactome:R-RNO-2173791|reactome:R-RNO-420029|dip:DIP-33271N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:pCIhxZdK3JRmJvgDmVgEtDI7fjc10116 rogid:pCIhxZdK3JRmJvgDmVgEtDI7fjc10116 rigid:y+GHeuk1n3HWQAt3LrigwIRPtf8 false sufficient binding region:2-83 sufficient binding region:2-83 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z340 uniprotkb:Q9Z340 intact:EBI-349441|ensembl:ENSRNOP00000048964 intact:EBI-349441|ensembl:ENSRNOP00000048964 psi-mi:pard3_rat(display_long)|uniprotkb:Pard3(gene name)|psi-mi:Pard3(display_short)|uniprotkb:Par3(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:Atypical PKC-specific-binding protein(gene name synonym) psi-mi:pard3_rat(display_long)|uniprotkb:Pard3(gene name)|psi-mi:Pard3(display_short)|uniprotkb:Par3(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:Atypical PKC-specific-binding protein(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Zhang et al. (2013) pubmed:23643951|doi:10.1016/j.str.2013.04.004|imex:IM-21030 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16056989|imex:IM-21030-4|dip:DIP-190646E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620374|refseq:NP_112514.1|ensembl:ENSRNOG00000032437(gene)|ensembl:ENSRNOT00000042623(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003383"(apical constriction)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0008104"(protein localization)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045177"(apical part of cell)|go:"GO:0005912"(adherens junction)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|rcsb pdb:2K1Z|rcsb pdb:2K20|rcsb pdb:2NS5|rcsb pdb:2OGP|rcsb pdb:3ZEE|rcsb pdb:4DC2|rcsb pdb:4I6P|rcsb pdb:6JUE|reactome:R-RNO-2173791|reactome:R-RNO-420029|dip:DIP-33271N rgd:620374|refseq:NP_112514.1|ensembl:ENSRNOG00000032437(gene)|ensembl:ENSRNOT00000042623(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003383"(apical constriction)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0008104"(protein localization)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045177"(apical part of cell)|go:"GO:0005912"(adherens junction)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|rcsb pdb:2K1Z|rcsb pdb:2K20|rcsb pdb:2NS5|rcsb pdb:2OGP|rcsb pdb:3ZEE|rcsb pdb:4DC2|rcsb pdb:4I6P|rcsb pdb:6JUE|reactome:R-RNO-2173791|reactome:R-RNO-420029|dip:DIP-33271N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:pCIhxZdK3JRmJvgDmVgEtDI7fjc10116 rogid:pCIhxZdK3JRmJvgDmVgEtDI7fjc10116 rigid:y+GHeuk1n3HWQAt3LrigwIRPtf8 false sufficient binding region:2-83|mutation decreasing interaction strength:9-9|mutation decreasing interaction strength:4-4|mutation decreasing interaction strength:70-70,13-13 sufficient binding region:2-83|mutation decreasing interaction strength:9-9|mutation decreasing interaction strength:4-4|mutation decreasing interaction strength:70-70,13-13 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z340 uniprotkb:Q9Z340 intact:EBI-349441|ensembl:ENSRNOP00000048964 intact:EBI-349441|ensembl:ENSRNOP00000048964 psi-mi:pard3_rat(display_long)|uniprotkb:Pard3(gene name)|psi-mi:Pard3(display_short)|uniprotkb:Par3(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:Atypical PKC-specific-binding protein(gene name synonym) psi-mi:pard3_rat(display_long)|uniprotkb:Pard3(gene name)|psi-mi:Pard3(display_short)|uniprotkb:Par3(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:Atypical PKC-specific-binding protein(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Zhang et al. (2013) pubmed:23643951|doi:10.1016/j.str.2013.04.004|imex:IM-21030 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16057018|imex:IM-21030-5|dip:DIP-190646E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620374|refseq:NP_112514.1|ensembl:ENSRNOG00000032437(gene)|ensembl:ENSRNOT00000042623(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003383"(apical constriction)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0008104"(protein localization)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045177"(apical part of cell)|go:"GO:0005912"(adherens junction)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|rcsb pdb:2K1Z|rcsb pdb:2K20|rcsb pdb:2NS5|rcsb pdb:2OGP|rcsb pdb:3ZEE|rcsb pdb:4DC2|rcsb pdb:4I6P|rcsb pdb:6JUE|reactome:R-RNO-2173791|reactome:R-RNO-420029|dip:DIP-33271N rgd:620374|refseq:NP_112514.1|ensembl:ENSRNOG00000032437(gene)|ensembl:ENSRNOT00000042623(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003383"(apical constriction)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0008104"(protein localization)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045177"(apical part of cell)|go:"GO:0005912"(adherens junction)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|rcsb pdb:2K1Z|rcsb pdb:2K20|rcsb pdb:2NS5|rcsb pdb:2OGP|rcsb pdb:3ZEE|rcsb pdb:4DC2|rcsb pdb:4I6P|rcsb pdb:6JUE|reactome:R-RNO-2173791|reactome:R-RNO-420029|dip:DIP-33271N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:pCIhxZdK3JRmJvgDmVgEtDI7fjc10116 rogid:pCIhxZdK3JRmJvgDmVgEtDI7fjc10116 rigid:y+GHeuk1n3HWQAt3LrigwIRPtf8 false sufficient binding region:2-83 sufficient binding region:2-83 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z340 uniprotkb:Q9Z340 intact:EBI-349441|ensembl:ENSRNOP00000048964 intact:EBI-349441|ensembl:ENSRNOP00000048964 psi-mi:pard3_rat(display_long)|uniprotkb:Pard3(gene name)|psi-mi:Pard3(display_short)|uniprotkb:Par3(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:Atypical PKC-specific-binding protein(gene name synonym) psi-mi:pard3_rat(display_long)|uniprotkb:Pard3(gene name)|psi-mi:Pard3(display_short)|uniprotkb:Par3(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:Atypical PKC-specific-binding protein(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Zhang et al. (2013) pubmed:23643951|doi:10.1016/j.str.2013.04.004|imex:IM-21030 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16057037|imex:IM-21030-6|dip:DIP-190646E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620374|refseq:NP_112514.1|ensembl:ENSRNOG00000032437(gene)|ensembl:ENSRNOT00000042623(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003383"(apical constriction)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0008104"(protein localization)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045177"(apical part of cell)|go:"GO:0005912"(adherens junction)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|rcsb pdb:2K1Z|rcsb pdb:2K20|rcsb pdb:2NS5|rcsb pdb:2OGP|rcsb pdb:3ZEE|rcsb pdb:4DC2|rcsb pdb:4I6P|rcsb pdb:6JUE|reactome:R-RNO-2173791|reactome:R-RNO-420029|dip:DIP-33271N rgd:620374|refseq:NP_112514.1|ensembl:ENSRNOG00000032437(gene)|ensembl:ENSRNOT00000042623(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003383"(apical constriction)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0008104"(protein localization)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045177"(apical part of cell)|go:"GO:0005912"(adherens junction)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|rcsb pdb:2K1Z|rcsb pdb:2K20|rcsb pdb:2NS5|rcsb pdb:2OGP|rcsb pdb:3ZEE|rcsb pdb:4DC2|rcsb pdb:4I6P|rcsb pdb:6JUE|reactome:R-RNO-2173791|reactome:R-RNO-420029|dip:DIP-33271N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:pCIhxZdK3JRmJvgDmVgEtDI7fjc10116 rogid:pCIhxZdK3JRmJvgDmVgEtDI7fjc10116 rigid:y+GHeuk1n3HWQAt3LrigwIRPtf8 false sufficient binding region:2-83 sufficient binding region:2-83 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z340 uniprotkb:Q9Z340 intact:EBI-349441|ensembl:ENSRNOP00000048964 intact:EBI-349441|ensembl:ENSRNOP00000048964 psi-mi:pard3_rat(display_long)|uniprotkb:Pard3(gene name)|psi-mi:Pard3(display_short)|uniprotkb:Par3(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:Atypical PKC-specific-binding protein(gene name synonym) psi-mi:pard3_rat(display_long)|uniprotkb:Pard3(gene name)|psi-mi:Pard3(display_short)|uniprotkb:Par3(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:Atypical PKC-specific-binding protein(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Zhang et al. (2013) pubmed:23643951|doi:10.1016/j.str.2013.04.004|imex:IM-21030 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16057055|imex:IM-21030-7|dip:DIP-190646E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620374|refseq:NP_112514.1|ensembl:ENSRNOG00000032437(gene)|ensembl:ENSRNOT00000042623(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003383"(apical constriction)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0008104"(protein localization)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045177"(apical part of cell)|go:"GO:0005912"(adherens junction)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|rcsb pdb:2K1Z|rcsb pdb:2K20|rcsb pdb:2NS5|rcsb pdb:2OGP|rcsb pdb:3ZEE|rcsb pdb:4DC2|rcsb pdb:4I6P|rcsb pdb:6JUE|reactome:R-RNO-2173791|reactome:R-RNO-420029|dip:DIP-33271N rgd:620374|refseq:NP_112514.1|ensembl:ENSRNOG00000032437(gene)|ensembl:ENSRNOT00000042623(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003383"(apical constriction)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0008104"(protein localization)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045177"(apical part of cell)|go:"GO:0005912"(adherens junction)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|rcsb pdb:2K1Z|rcsb pdb:2K20|rcsb pdb:2NS5|rcsb pdb:2OGP|rcsb pdb:3ZEE|rcsb pdb:4DC2|rcsb pdb:4I6P|rcsb pdb:6JUE|reactome:R-RNO-2173791|reactome:R-RNO-420029|dip:DIP-33271N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:pCIhxZdK3JRmJvgDmVgEtDI7fjc10116 rogid:pCIhxZdK3JRmJvgDmVgEtDI7fjc10116 rigid:y+GHeuk1n3HWQAt3LrigwIRPtf8 false mutation disrupting interaction strength:70-70,13-13|sufficient binding region:2-83 mutation disrupting interaction strength:70-70,13-13|sufficient binding region:2-83 - 0 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)