#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q5JII1	uniprotkb:Q5JII0	intact:EBI-16020973|ensemblbacteria:BAD86189|uniprotkb:Q5H7P6	intact:EBI-16020957|ensemblbacteria:BAD86190|uniprotkb:Q5H7P7	psi-mi:q5jii1_theko(display_long)|uniprotkb:Tk-hypD(gene name)|psi-mi:Tk-hypD(display_short)|uniprotkb:TK2000(locus name)	psi-mi:q5jii0_theko(display_long)|uniprotkb:Tk-hypC(gene name)|psi-mi:Tk-hypC(display_short)|uniprotkb:TK2001(locus name)	psi-mi:"MI:0071"(molecular sieving)	Watanabe et al. (2012)	pubmed:23123111|doi:10.1016/j.str.2012.09.018|imex:IM-20602	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16020990|imex:IM-20602-1|dip:DIP-190155E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:BAD86189(transcript)|ensemblbacteria:TK2000(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051604"(protein maturation)|go:"GO:0070025"(carbon monoxide binding)|interpro:IPR002780(Hydrogenase formation HypD protein)|interpro:IPR042243|interpro:IPR042244|rcsb pdb:2Z1D|rcsb pdb:3VYR|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|dip:DIP-59990N|refseq:WP_011250950.1	ensemblbacteria:BAD86190(transcript)|ensemblbacteria:TK2001(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0051604"(protein maturation)|go:"GO:1902670"(carbon dioxide binding)|interpro:IPR001109("Hydrogenase expression/formation protein (HUPF/HYPC)")|interpro:IPR019812|rcsb pdb:2Z1C|rcsb pdb:3VYR|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|dip:DIP-59989N|refseq:WP_011250951.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:CL9e5MYNi4JkVx1Gqbgc1ZA58IM69014	rogid:AZzOAMG1eJlIb3e5/rgIodC40ro69014	rigid:oT3OpGc3wtPRvOjSQ8mqf+WYNWE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5JII1	uniprotkb:Q5JII0	intact:EBI-16020973|ensemblbacteria:BAD86189|uniprotkb:Q5H7P6	intact:EBI-16020957|ensemblbacteria:BAD86190|uniprotkb:Q5H7P7	psi-mi:q5jii1_theko(display_long)|uniprotkb:Tk-hypD(gene name)|psi-mi:Tk-hypD(display_short)|uniprotkb:TK2000(locus name)	psi-mi:q5jii0_theko(display_long)|uniprotkb:Tk-hypC(gene name)|psi-mi:Tk-hypC(display_short)|uniprotkb:TK2001(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Watanabe et al. (2012)	pubmed:23123111|doi:10.1016/j.str.2012.09.018|imex:IM-20602	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16021008|imex:IM-20602-2|dip:DIP-190155E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:BAD86189(transcript)|ensemblbacteria:TK2000(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051604"(protein maturation)|go:"GO:0070025"(carbon monoxide binding)|interpro:IPR002780(Hydrogenase formation HypD protein)|interpro:IPR042243|interpro:IPR042244|rcsb pdb:2Z1D|rcsb pdb:3VYR|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|dip:DIP-59990N|refseq:WP_011250950.1	ensemblbacteria:BAD86190(transcript)|ensemblbacteria:TK2001(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0051604"(protein maturation)|go:"GO:1902670"(carbon dioxide binding)|interpro:IPR001109("Hydrogenase expression/formation protein (HUPF/HYPC)")|interpro:IPR019812|rcsb pdb:2Z1C|rcsb pdb:3VYR|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|dip:DIP-59989N|refseq:WP_011250951.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:CL9e5MYNi4JkVx1Gqbgc1ZA58IM69014	rogid:AZzOAMG1eJlIb3e5/rgIodC40ro69014	rigid:oT3OpGc3wtPRvOjSQ8mqf+WYNWE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5JII7	uniprotkb:Q5JII7	intact:EBI-16021025|ensemblbacteria:BAD86182	intact:EBI-16021025|ensemblbacteria:BAD86182	psi-mi:q5jii7_theko(display_long)|uniprotkb:TK1993(locus name)	psi-mi:q5jii7_theko(display_long)|uniprotkb:TK1993(locus name)	psi-mi:"MI:0071"(molecular sieving)	Watanabe et al. (2012)	pubmed:23123111|doi:10.1016/j.str.2012.09.018|imex:IM-20602	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16021045|imex:IM-20602-3|dip:DIP-190157E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:BAD86182(transcript)|ensemblbacteria:TK1993(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046892"(peptidyl-S-carbamoyl-L-cysteine dehydration)|go:"GO:0051604"(protein maturation)|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR011854(Hydrogenase expression/formation protein HypE)|interpro:IPR016188(PurM, N-terminal-like)|interpro:IPR036676|interpro:IPR036921|rcsb pdb:2Z1E|rcsb pdb:2Z1F|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|rcsb pdb:3WJP|rcsb pdb:3WJQ|rcsb pdb:3WJR|dip:DIP-59991N|refseq:WP_011250943.1	ensemblbacteria:BAD86182(transcript)|ensemblbacteria:TK1993(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046892"(peptidyl-S-carbamoyl-L-cysteine dehydration)|go:"GO:0051604"(protein maturation)|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR011854(Hydrogenase expression/formation protein HypE)|interpro:IPR016188(PurM, N-terminal-like)|interpro:IPR036676|interpro:IPR036921|rcsb pdb:2Z1E|rcsb pdb:2Z1F|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|rcsb pdb:3WJP|rcsb pdb:3WJQ|rcsb pdb:3WJR|dip:DIP-59991N|refseq:WP_011250943.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:Lk73gkLEDHcLbF+xTNjEWaVmpQ469014	rogid:Lk73gkLEDHcLbF+xTNjEWaVmpQ469014	rigid:tdgsH3MelYPvwJkyj6GSa/mt+/c	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5JII1	uniprotkb:Q5JII0	intact:EBI-16020973|ensemblbacteria:BAD86189|uniprotkb:Q5H7P6	intact:EBI-16020957|ensemblbacteria:BAD86190|uniprotkb:Q5H7P7	psi-mi:q5jii1_theko(display_long)|uniprotkb:Tk-hypD(gene name)|psi-mi:Tk-hypD(display_short)|uniprotkb:TK2000(locus name)	psi-mi:q5jii0_theko(display_long)|uniprotkb:Tk-hypC(gene name)|psi-mi:Tk-hypC(display_short)|uniprotkb:TK2001(locus name)	psi-mi:"MI:0096"(pull down)	Watanabe et al. (2012)	pubmed:23123111|doi:10.1016/j.str.2012.09.018|imex:IM-20602	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16021061|imex:IM-20602-4|dip:DIP-190155E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:BAD86189(transcript)|ensemblbacteria:TK2000(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051604"(protein maturation)|go:"GO:0070025"(carbon monoxide binding)|interpro:IPR002780(Hydrogenase formation HypD protein)|interpro:IPR042243|interpro:IPR042244|rcsb pdb:2Z1D|rcsb pdb:3VYR|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|dip:DIP-59990N|refseq:WP_011250950.1	ensemblbacteria:BAD86190(transcript)|ensemblbacteria:TK2001(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0051604"(protein maturation)|go:"GO:1902670"(carbon dioxide binding)|interpro:IPR001109("Hydrogenase expression/formation protein (HUPF/HYPC)")|interpro:IPR019812|rcsb pdb:2Z1C|rcsb pdb:3VYR|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|dip:DIP-59989N|refseq:WP_011250951.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:CL9e5MYNi4JkVx1Gqbgc1ZA58IM69014	rogid:AZzOAMG1eJlIb3e5/rgIodC40ro69014	rigid:oT3OpGc3wtPRvOjSQ8mqf+WYNWE	false	strep ii tag:c-c	mutation disrupting interaction strength:48-48|mutation disrupting interaction strength:32-32|mutation disrupting interaction strength:32-32|mutation disrupting interaction strength:50-50|mutation disrupting interaction strength:50-50|mutation decreasing interaction strength:43-43|mutation decreasing interaction strength:43-43|mutation disrupting interaction strength:48-48	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q5JII1	uniprotkb:Q5JII7	intact:EBI-16020973|ensemblbacteria:BAD86189|uniprotkb:Q5H7P6	intact:EBI-16021025|ensemblbacteria:BAD86182	psi-mi:q5jii1_theko(display_long)|uniprotkb:Tk-hypD(gene name)|psi-mi:Tk-hypD(display_short)|uniprotkb:TK2000(locus name)	psi-mi:q5jii7_theko(display_long)|uniprotkb:TK1993(locus name)	psi-mi:"MI:0096"(pull down)	Watanabe et al. (2012)	pubmed:23123111|doi:10.1016/j.str.2012.09.018|imex:IM-20602	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16021102|imex:IM-20602-5|dip:DIP-190156E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:BAD86189(transcript)|ensemblbacteria:TK2000(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051604"(protein maturation)|go:"GO:0070025"(carbon monoxide binding)|interpro:IPR002780(Hydrogenase formation HypD protein)|interpro:IPR042243|interpro:IPR042244|rcsb pdb:2Z1D|rcsb pdb:3VYR|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|dip:DIP-59990N|refseq:WP_011250950.1	ensemblbacteria:BAD86182(transcript)|ensemblbacteria:TK1993(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046892"(peptidyl-S-carbamoyl-L-cysteine dehydration)|go:"GO:0051604"(protein maturation)|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR011854(Hydrogenase expression/formation protein HypE)|interpro:IPR016188(PurM, N-terminal-like)|interpro:IPR036676|interpro:IPR036921|rcsb pdb:2Z1E|rcsb pdb:2Z1F|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|rcsb pdb:3WJP|rcsb pdb:3WJQ|rcsb pdb:3WJR|dip:DIP-59991N|refseq:WP_011250943.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:CL9e5MYNi4JkVx1Gqbgc1ZA58IM69014	rogid:Lk73gkLEDHcLbF+xTNjEWaVmpQ469014	rigid:YMPH+psIN/aCV6Z+Ke2w/TCns6M	false	strep ii tag:c-c	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q5JII1	uniprotkb:Q5JII0	intact:EBI-16020973|ensemblbacteria:BAD86189|uniprotkb:Q5H7P6	intact:EBI-16020957|ensemblbacteria:BAD86190|uniprotkb:Q5H7P7	psi-mi:q5jii1_theko(display_long)|uniprotkb:Tk-hypD(gene name)|psi-mi:Tk-hypD(display_short)|uniprotkb:TK2000(locus name)	psi-mi:q5jii0_theko(display_long)|uniprotkb:Tk-hypC(gene name)|psi-mi:Tk-hypC(display_short)|uniprotkb:TK2001(locus name)	psi-mi:"MI:0096"(pull down)	Watanabe et al. (2012)	pubmed:23123111|doi:10.1016/j.str.2012.09.018|imex:IM-20602	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16021102|imex:IM-20602-5|dip:DIP-190156E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:BAD86189(transcript)|ensemblbacteria:TK2000(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051604"(protein maturation)|go:"GO:0070025"(carbon monoxide binding)|interpro:IPR002780(Hydrogenase formation HypD protein)|interpro:IPR042243|interpro:IPR042244|rcsb pdb:2Z1D|rcsb pdb:3VYR|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|dip:DIP-59990N|refseq:WP_011250950.1	ensemblbacteria:BAD86190(transcript)|ensemblbacteria:TK2001(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0051604"(protein maturation)|go:"GO:1902670"(carbon dioxide binding)|interpro:IPR001109("Hydrogenase expression/formation protein (HUPF/HYPC)")|interpro:IPR019812|rcsb pdb:2Z1C|rcsb pdb:3VYR|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|dip:DIP-59989N|refseq:WP_011250951.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:CL9e5MYNi4JkVx1Gqbgc1ZA58IM69014	rogid:AZzOAMG1eJlIb3e5/rgIodC40ro69014	rigid:YMPH+psIN/aCV6Z+Ke2w/TCns6M	false	strep ii tag:c-c	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q5JII1	uniprotkb:Q5JII0	intact:EBI-16020973|ensemblbacteria:BAD86189|uniprotkb:Q5H7P6	intact:EBI-16020957|ensemblbacteria:BAD86190|uniprotkb:Q5H7P7	psi-mi:q5jii1_theko(display_long)|uniprotkb:Tk-hypD(gene name)|psi-mi:Tk-hypD(display_short)|uniprotkb:TK2000(locus name)	psi-mi:q5jii0_theko(display_long)|uniprotkb:Tk-hypC(gene name)|psi-mi:Tk-hypC(display_short)|uniprotkb:TK2001(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Watanabe et al. (2012)	pubmed:23123111|doi:10.1016/j.str.2012.09.018|imex:IM-20602	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16021122|imex:IM-20602-6|dip:DIP-190155E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:BAD86189(transcript)|ensemblbacteria:TK2000(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051604"(protein maturation)|go:"GO:0070025"(carbon monoxide binding)|interpro:IPR002780(Hydrogenase formation HypD protein)|interpro:IPR042243|interpro:IPR042244|rcsb pdb:2Z1D|rcsb pdb:3VYR|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|dip:DIP-59990N|refseq:WP_011250950.1	ensemblbacteria:BAD86190(transcript)|ensemblbacteria:TK2001(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0051604"(protein maturation)|go:"GO:1902670"(carbon dioxide binding)|interpro:IPR001109("Hydrogenase expression/formation protein (HUPF/HYPC)")|interpro:IPR019812|rcsb pdb:2Z1C|rcsb pdb:3VYR|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|dip:DIP-59989N|refseq:WP_011250951.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:CL9e5MYNi4JkVx1Gqbgc1ZA58IM69014	rogid:AZzOAMG1eJlIb3e5/rgIodC40ro69014	rigid:oT3OpGc3wtPRvOjSQ8mqf+WYNWE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5JII0	uniprotkb:Q5JII1	intact:EBI-16020957|ensemblbacteria:BAD86190|uniprotkb:Q5H7P7	intact:EBI-16020973|ensemblbacteria:BAD86189|uniprotkb:Q5H7P6	psi-mi:q5jii0_theko(display_long)|uniprotkb:Tk-hypC(gene name)|psi-mi:Tk-hypC(display_short)|uniprotkb:TK2001(locus name)	psi-mi:q5jii1_theko(display_long)|uniprotkb:Tk-hypD(gene name)|psi-mi:Tk-hypD(display_short)|uniprotkb:TK2000(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Watanabe et al. (2012)	pubmed:23123111|doi:10.1016/j.str.2012.09.018|imex:IM-20602	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16021142|imex:IM-20602-7|dip:DIP-190156E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:BAD86190(transcript)|ensemblbacteria:TK2001(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0051604"(protein maturation)|go:"GO:1902670"(carbon dioxide binding)|interpro:IPR001109("Hydrogenase expression/formation protein (HUPF/HYPC)")|interpro:IPR019812|rcsb pdb:2Z1C|rcsb pdb:3VYR|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|dip:DIP-59989N|refseq:WP_011250951.1	ensemblbacteria:BAD86189(transcript)|ensemblbacteria:TK2000(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051604"(protein maturation)|go:"GO:0070025"(carbon monoxide binding)|interpro:IPR002780(Hydrogenase formation HypD protein)|interpro:IPR042243|interpro:IPR042244|rcsb pdb:2Z1D|rcsb pdb:3VYR|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|dip:DIP-59990N|refseq:WP_011250950.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:AZzOAMG1eJlIb3e5/rgIodC40ro69014	rogid:CL9e5MYNi4JkVx1Gqbgc1ZA58IM69014	rigid:YMPH+psIN/aCV6Z+Ke2w/TCns6M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5JII0	uniprotkb:Q5JII7	intact:EBI-16020957|ensemblbacteria:BAD86190|uniprotkb:Q5H7P7	intact:EBI-16021025|ensemblbacteria:BAD86182	psi-mi:q5jii0_theko(display_long)|uniprotkb:Tk-hypC(gene name)|psi-mi:Tk-hypC(display_short)|uniprotkb:TK2001(locus name)	psi-mi:q5jii7_theko(display_long)|uniprotkb:TK1993(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Watanabe et al. (2012)	pubmed:23123111|doi:10.1016/j.str.2012.09.018|imex:IM-20602	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16021142|imex:IM-20602-7|dip:DIP-190156E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:BAD86190(transcript)|ensemblbacteria:TK2001(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0051604"(protein maturation)|go:"GO:1902670"(carbon dioxide binding)|interpro:IPR001109("Hydrogenase expression/formation protein (HUPF/HYPC)")|interpro:IPR019812|rcsb pdb:2Z1C|rcsb pdb:3VYR|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|dip:DIP-59989N|refseq:WP_011250951.1	ensemblbacteria:BAD86182(transcript)|ensemblbacteria:TK1993(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046892"(peptidyl-S-carbamoyl-L-cysteine dehydration)|go:"GO:0051604"(protein maturation)|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR011854(Hydrogenase expression/formation protein HypE)|interpro:IPR016188(PurM, N-terminal-like)|interpro:IPR036676|interpro:IPR036921|rcsb pdb:2Z1E|rcsb pdb:2Z1F|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|rcsb pdb:3WJP|rcsb pdb:3WJQ|rcsb pdb:3WJR|dip:DIP-59991N|refseq:WP_011250943.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:AZzOAMG1eJlIb3e5/rgIodC40ro69014	rogid:Lk73gkLEDHcLbF+xTNjEWaVmpQ469014	rigid:YMPH+psIN/aCV6Z+Ke2w/TCns6M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5JII0	uniprotkb:Q5JII1	intact:EBI-16020957|ensemblbacteria:BAD86190|uniprotkb:Q5H7P7	intact:EBI-16020973|ensemblbacteria:BAD86189|uniprotkb:Q5H7P6	psi-mi:q5jii0_theko(display_long)|uniprotkb:Tk-hypC(gene name)|psi-mi:Tk-hypC(display_short)|uniprotkb:TK2001(locus name)	psi-mi:q5jii1_theko(display_long)|uniprotkb:Tk-hypD(gene name)|psi-mi:Tk-hypD(display_short)|uniprotkb:TK2000(locus name)	psi-mi:"MI:0071"(molecular sieving)	Watanabe et al. (2012)	pubmed:23123111|doi:10.1016/j.str.2012.09.018|imex:IM-20602	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16021160|imex:IM-20602-8|dip:DIP-190156E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:BAD86190(transcript)|ensemblbacteria:TK2001(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0051604"(protein maturation)|go:"GO:1902670"(carbon dioxide binding)|interpro:IPR001109("Hydrogenase expression/formation protein (HUPF/HYPC)")|interpro:IPR019812|rcsb pdb:2Z1C|rcsb pdb:3VYR|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|dip:DIP-59989N|refseq:WP_011250951.1	ensemblbacteria:BAD86189(transcript)|ensemblbacteria:TK2000(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051604"(protein maturation)|go:"GO:0070025"(carbon monoxide binding)|interpro:IPR002780(Hydrogenase formation HypD protein)|interpro:IPR042243|interpro:IPR042244|rcsb pdb:2Z1D|rcsb pdb:3VYR|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|dip:DIP-59990N|refseq:WP_011250950.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:AZzOAMG1eJlIb3e5/rgIodC40ro69014	rogid:CL9e5MYNi4JkVx1Gqbgc1ZA58IM69014	rigid:YMPH+psIN/aCV6Z+Ke2w/TCns6M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5JII0	uniprotkb:Q5JII7	intact:EBI-16020957|ensemblbacteria:BAD86190|uniprotkb:Q5H7P7	intact:EBI-16021025|ensemblbacteria:BAD86182	psi-mi:q5jii0_theko(display_long)|uniprotkb:Tk-hypC(gene name)|psi-mi:Tk-hypC(display_short)|uniprotkb:TK2001(locus name)	psi-mi:q5jii7_theko(display_long)|uniprotkb:TK1993(locus name)	psi-mi:"MI:0071"(molecular sieving)	Watanabe et al. (2012)	pubmed:23123111|doi:10.1016/j.str.2012.09.018|imex:IM-20602	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16021160|imex:IM-20602-8|dip:DIP-190156E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:BAD86190(transcript)|ensemblbacteria:TK2001(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0051604"(protein maturation)|go:"GO:1902670"(carbon dioxide binding)|interpro:IPR001109("Hydrogenase expression/formation protein (HUPF/HYPC)")|interpro:IPR019812|rcsb pdb:2Z1C|rcsb pdb:3VYR|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|dip:DIP-59989N|refseq:WP_011250951.1	ensemblbacteria:BAD86182(transcript)|ensemblbacteria:TK1993(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046892"(peptidyl-S-carbamoyl-L-cysteine dehydration)|go:"GO:0051604"(protein maturation)|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR011854(Hydrogenase expression/formation protein HypE)|interpro:IPR016188(PurM, N-terminal-like)|interpro:IPR036676|interpro:IPR036921|rcsb pdb:2Z1E|rcsb pdb:2Z1F|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|rcsb pdb:3WJP|rcsb pdb:3WJQ|rcsb pdb:3WJR|dip:DIP-59991N|refseq:WP_011250943.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:AZzOAMG1eJlIb3e5/rgIodC40ro69014	rogid:Lk73gkLEDHcLbF+xTNjEWaVmpQ469014	rigid:YMPH+psIN/aCV6Z+Ke2w/TCns6M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5JII7	uniprotkb:Q5JII1	intact:EBI-16021025|ensemblbacteria:BAD86182	intact:EBI-16020973|ensemblbacteria:BAD86189|uniprotkb:Q5H7P6	psi-mi:q5jii7_theko(display_long)|uniprotkb:TK1993(locus name)	psi-mi:q5jii1_theko(display_long)|uniprotkb:Tk-hypD(gene name)|psi-mi:Tk-hypD(display_short)|uniprotkb:TK2000(locus name)	psi-mi:"MI:0096"(pull down)	Watanabe et al. (2012)	pubmed:23123111|doi:10.1016/j.str.2012.09.018|imex:IM-20602	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16021178|imex:IM-20602-9|dip:DIP-190158E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:BAD86182(transcript)|ensemblbacteria:TK1993(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046892"(peptidyl-S-carbamoyl-L-cysteine dehydration)|go:"GO:0051604"(protein maturation)|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR011854(Hydrogenase expression/formation protein HypE)|interpro:IPR016188(PurM, N-terminal-like)|interpro:IPR036676|interpro:IPR036921|rcsb pdb:2Z1E|rcsb pdb:2Z1F|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|rcsb pdb:3WJP|rcsb pdb:3WJQ|rcsb pdb:3WJR|dip:DIP-59991N|refseq:WP_011250943.1	ensemblbacteria:BAD86189(transcript)|ensemblbacteria:TK2000(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051604"(protein maturation)|go:"GO:0070025"(carbon monoxide binding)|interpro:IPR002780(Hydrogenase formation HypD protein)|interpro:IPR042243|interpro:IPR042244|rcsb pdb:2Z1D|rcsb pdb:3VYR|rcsb pdb:3VYS|rcsb pdb:3VYT|rcsb pdb:3VYU|dip:DIP-59990N|refseq:WP_011250950.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:Lk73gkLEDHcLbF+xTNjEWaVmpQ469014	rogid:CL9e5MYNi4JkVx1Gqbgc1ZA58IM69014	rigid:qpVcjaUgcQpjfFvp5n2CniUqgrE	false	mutation disrupting interaction strength:320-320|mutation disrupting interaction strength:320-320|mutation disrupting interaction strength:324-324	strep ii tag:c-c	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)