#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P06802	uniprotkb:P06802	intact:EBI-16016057|uniprotkb:Q542E9|uniprotkb:Q924C4	intact:EBI-16016057|uniprotkb:Q542E9|uniprotkb:Q924C4	psi-mi:enpp1_mouse(display_long)|uniprotkb:Enpp1(gene name)|psi-mi:Enpp1(display_short)|uniprotkb:Npps(gene name synonym)|uniprotkb:Pc1(gene name synonym)|uniprotkb:Pdnp1(gene name synonym)|uniprotkb:Lymphocyte antigen 41(gene name synonym)|uniprotkb:Phosphodiesterase I/nucleotide pyrophosphatase 1(gene name synonym)|uniprotkb:Plasma-cell membrane glycoprotein PC-1(gene name synonym)	psi-mi:enpp1_mouse(display_long)|uniprotkb:Enpp1(gene name)|psi-mi:Enpp1(display_short)|uniprotkb:Npps(gene name synonym)|uniprotkb:Pc1(gene name synonym)|uniprotkb:Pdnp1(gene name synonym)|uniprotkb:Lymphocyte antigen 41(gene name synonym)|uniprotkb:Phosphodiesterase I/nucleotide pyrophosphatase 1(gene name synonym)|uniprotkb:Plasma-cell membrane glycoprotein PC-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Jansen et al. (2012)	pubmed:23041369|doi:10.1016/j.str.2012.09.001|imex:IM-18600	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16016122|imex:IM-18600-1|dip:DIP-190056E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003676"(nucleic acid binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0004551"(nucleotide diphosphatase activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0006955"(immune response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009143"(nucleoside triphosphate catabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0030505"(inorganic diphosphate transport)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0030730"(sequestering of triglyceride)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035529"(NADH pyrophosphatase activity)|go:"GO:0036218"(dTTP diphosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046849"(bone remodeling)|go:"GO:0050427"(3'-phosphoadenosine 5'-phosphosulfate metabolic process)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0106177"(cyclic-GMP-AMP hydrolase activity)|go:"GO:1990787"(negative regulation of hh target transcription factor activity)|interpro:IPR001212(Somatomedin B)|interpro:IPR001604(DNA/RNA non-specific endonuclease)|interpro:IPR002591(Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR020436|interpro:IPR020821|interpro:IPR029890|interpro:IPR036024|rcsb pdb:4B56|rcsb pdb:4GTW|rcsb pdb:4GTX|rcsb pdb:4GTY|rcsb pdb:4GTZ|rcsb pdb:6AEK|rcsb pdb:6AEL|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|reactome:R-MMU-196843|refseq:NP_001295256.1|dip:DIP-59981N	go:"GO:0003676"(nucleic acid binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0004551"(nucleotide diphosphatase activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0006955"(immune response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009143"(nucleoside triphosphate catabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0030505"(inorganic diphosphate transport)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0030730"(sequestering of triglyceride)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035529"(NADH pyrophosphatase activity)|go:"GO:0036218"(dTTP diphosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046849"(bone remodeling)|go:"GO:0050427"(3'-phosphoadenosine 5'-phosphosulfate metabolic process)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0106177"(cyclic-GMP-AMP hydrolase activity)|go:"GO:1990787"(negative regulation of hh target transcription factor activity)|interpro:IPR001212(Somatomedin B)|interpro:IPR001604(DNA/RNA non-specific endonuclease)|interpro:IPR002591(Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR020436|interpro:IPR020821|interpro:IPR029890|interpro:IPR036024|rcsb pdb:4B56|rcsb pdb:4GTW|rcsb pdb:4GTX|rcsb pdb:4GTY|rcsb pdb:4GTZ|rcsb pdb:6AEK|rcsb pdb:6AEL|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|reactome:R-MMU-196843|refseq:NP_001295256.1|dip:DIP-59981N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:HIz2EHwxcL4lJV+QrJXG3z+HG0Q10090	rogid:HIz2EHwxcL4lJV+QrJXG3z+HG0Q10090	rigid:/f3KWuL28nfLf7qrAKl0Or2fxPc	false	enhanced green fluorescent protein tag:c-c	mutation disrupting interaction strength:83-83,75-75|myc tag:c-c|mutation disrupting interaction strength:83-83,75-75,67-67	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P06802	uniprotkb:P06802	intact:EBI-16016057|uniprotkb:Q542E9|uniprotkb:Q924C4	intact:EBI-16016057|uniprotkb:Q542E9|uniprotkb:Q924C4	psi-mi:enpp1_mouse(display_long)|uniprotkb:Enpp1(gene name)|psi-mi:Enpp1(display_short)|uniprotkb:Npps(gene name synonym)|uniprotkb:Pc1(gene name synonym)|uniprotkb:Pdnp1(gene name synonym)|uniprotkb:Lymphocyte antigen 41(gene name synonym)|uniprotkb:Phosphodiesterase I/nucleotide pyrophosphatase 1(gene name synonym)|uniprotkb:Plasma-cell membrane glycoprotein PC-1(gene name synonym)	psi-mi:enpp1_mouse(display_long)|uniprotkb:Enpp1(gene name)|psi-mi:Enpp1(display_short)|uniprotkb:Npps(gene name synonym)|uniprotkb:Pc1(gene name synonym)|uniprotkb:Pdnp1(gene name synonym)|uniprotkb:Lymphocyte antigen 41(gene name synonym)|uniprotkb:Phosphodiesterase I/nucleotide pyrophosphatase 1(gene name synonym)|uniprotkb:Plasma-cell membrane glycoprotein PC-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Jansen et al. (2012)	pubmed:23041369|doi:10.1016/j.str.2012.09.001|imex:IM-18600	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16016152|imex:IM-18600-2|dip:DIP-190056E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003676"(nucleic acid binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0004551"(nucleotide diphosphatase activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0006955"(immune response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009143"(nucleoside triphosphate catabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0030505"(inorganic diphosphate transport)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0030730"(sequestering of triglyceride)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035529"(NADH pyrophosphatase activity)|go:"GO:0036218"(dTTP diphosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046849"(bone remodeling)|go:"GO:0050427"(3'-phosphoadenosine 5'-phosphosulfate metabolic process)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0106177"(cyclic-GMP-AMP hydrolase activity)|go:"GO:1990787"(negative regulation of hh target transcription factor activity)|interpro:IPR001212(Somatomedin B)|interpro:IPR001604(DNA/RNA non-specific endonuclease)|interpro:IPR002591(Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR020436|interpro:IPR020821|interpro:IPR029890|interpro:IPR036024|rcsb pdb:4B56|rcsb pdb:4GTW|rcsb pdb:4GTX|rcsb pdb:4GTY|rcsb pdb:4GTZ|rcsb pdb:6AEK|rcsb pdb:6AEL|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|reactome:R-MMU-196843|refseq:NP_001295256.1|dip:DIP-59981N	go:"GO:0003676"(nucleic acid binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0004551"(nucleotide diphosphatase activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0006955"(immune response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009143"(nucleoside triphosphate catabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0030505"(inorganic diphosphate transport)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0030730"(sequestering of triglyceride)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035529"(NADH pyrophosphatase activity)|go:"GO:0036218"(dTTP diphosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046849"(bone remodeling)|go:"GO:0050427"(3'-phosphoadenosine 5'-phosphosulfate metabolic process)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0106177"(cyclic-GMP-AMP hydrolase activity)|go:"GO:1990787"(negative regulation of hh target transcription factor activity)|interpro:IPR001212(Somatomedin B)|interpro:IPR001604(DNA/RNA non-specific endonuclease)|interpro:IPR002591(Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR020436|interpro:IPR020821|interpro:IPR029890|interpro:IPR036024|rcsb pdb:4B56|rcsb pdb:4GTW|rcsb pdb:4GTX|rcsb pdb:4GTY|rcsb pdb:4GTZ|rcsb pdb:6AEK|rcsb pdb:6AEL|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|reactome:R-MMU-196843|refseq:NP_001295256.1|dip:DIP-59981N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:HIz2EHwxcL4lJV+QrJXG3z+HG0Q10090	rogid:HIz2EHwxcL4lJV+QrJXG3z+HG0Q10090	rigid:/f3KWuL28nfLf7qrAKl0Or2fxPc	false	enhanced green fluorescent protein tag:c-c	myc tag:c-c|mutation decreasing interaction strength:83-83,75-75|mutation disrupting interaction strength:83-83,75-75,67-67	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)