#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9NQS3-1 uniprotkb:Q9NQS3-1 intact:EBI-16007706|ensembl:ENSP00000418070 intact:EBI-16007706|ensembl:ENSP00000418070 psi-mi:q9nqs3-1(display_long)|uniprotkb:NECTIN3(gene name)|psi-mi:NECTIN3(display_short)|uniprotkb:PRR3(gene name synonym)|uniprotkb:PVRL3(gene name synonym)|uniprotkb:CDw113(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 3(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 3(gene name synonym) psi-mi:q9nqs3-1(display_long)|uniprotkb:NECTIN3(gene name)|psi-mi:NECTIN3(display_short)|uniprotkb:PRR3(gene name synonym)|uniprotkb:PVRL3(gene name synonym)|uniprotkb:CDw113(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 3(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 3(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16007716|imex:IM-18564-2|dip:DIP-189999E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2826725(isoform-parent)|ensembl:ENSG00000177707(gene)|ensembl:ENST00000485303(transcript) intact:EBI-2826725(isoform-parent)|ensembl:ENSG00000177707(gene)|ensembl:ENST00000485303(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:lzSScehKhxTPj0E6EmL+P+XXjB09606 rogid:lzSScehKhxTPj0E6EmL+P+XXjB09606 rigid:vvFx2Jc6qAm+z7hL6XHnIXgJf4g false sufficient binding region:58-359 sufficient binding region:58-359 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15223 uniprotkb:Q15223 intact:EBI-1771314|uniprotkb:O75465|uniprotkb:Q2M3D3|uniprotkb:Q9HBE6|uniprotkb:Q9HBW2|ensembl:ENSP00000264025 intact:EBI-1771314|uniprotkb:O75465|uniprotkb:Q2M3D3|uniprotkb:Q9HBE6|uniprotkb:Q9HBW2|ensembl:ENSP00000264025 psi-mi:nect1_human(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Herpesvirus Ig-like receptor(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:nect1_human(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Herpesvirus Ig-like receptor(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16007756|imex:IM-18564-4|dip:DIP-189997E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002846.3|refseq:NP_976030.1|refseq:NP_976031.1|dip:DIP-40302N|ensembl:ENSG00000110400(gene)|ensembl:ENST00000264025(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002934"(desmosome organization)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070166"(enamel mineralization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033314|interpro:IPR036179|interpro:IPR041849|interpro:IPR041850|rcsb pdb:3ALP|rcsb pdb:3SKU|rcsb pdb:3U82|rcsb pdb:3U83|rcsb pdb:4FMF|rcsb pdb:4MYW|reactome:R-HSA-418990|reactome:R-HSA-420597 refseq:NP_002846.3|refseq:NP_976030.1|refseq:NP_976031.1|dip:DIP-40302N|ensembl:ENSG00000110400(gene)|ensembl:ENST00000264025(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002934"(desmosome organization)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070166"(enamel mineralization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033314|interpro:IPR036179|interpro:IPR041849|interpro:IPR041850|rcsb pdb:3ALP|rcsb pdb:3SKU|rcsb pdb:3U82|rcsb pdb:3U83|rcsb pdb:4FMF|rcsb pdb:4MYW|reactome:R-HSA-418990|reactome:R-HSA-420597 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:/KqZN5Vhyc6Qrih7IyHnkN8nsaE9606 rogid:/KqZN5Vhyc6Qrih7IyHnkN8nsaE9606 rigid:NCMYoD0Gz5GbeGtahYjJIXHOcaQ false sufficient binding region:31-337 sufficient binding region:31-337 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92692 uniprotkb:Q9NQS3-1 intact:EBI-718419|uniprotkb:A8K5L5|uniprotkb:O75455|uniprotkb:Q96J29|uniprotkb:Q6IBI6|ensembl:ENSP00000252483 intact:EBI-16007706|ensembl:ENSP00000418070 psi-mi:nect2_human(display_long)|uniprotkb:NECTIN2(gene name)|psi-mi:NECTIN2(display_short)|uniprotkb:HVEB(gene name synonym)|uniprotkb:Herpes virus entry mediator B(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 2(gene name synonym)|uniprotkb:PRR2(gene name synonym)|uniprotkb:PVRL2(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 2(gene name synonym) psi-mi:q9nqs3-1(display_long)|uniprotkb:NECTIN3(gene name)|psi-mi:NECTIN3(display_short)|uniprotkb:PRR3(gene name synonym)|uniprotkb:PVRL3(gene name synonym)|uniprotkb:CDw113(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 3(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 3(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16007734|imex:IM-18564-3|dip:DIP-190003E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036189.1|refseq:NP_002847.1|ensembl:ENSG00000130202(gene)|ensembl:ENST00000252483(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001675"(acrosome assembly)|go:"GO:0002860"(positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:"GO:0002891"(positive regulation of immunoglobulin mediated immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007286"(spermatid development)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0009566"(fertilization)|go:"GO:0009986"(cell surface)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0030382"(sperm mitochondrion organization)|go:"GO:0032990"(cell part morphogenesis)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0042271"(susceptibility to natural killer cell mediated cytotoxicity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044406"(adhesion of symbiont to host)|go:"GO:0044782"(cilium organization)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046814"(coreceptor-mediated virion attachment to host cell)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051654"(establishment of mitochondrion localization)|go:"GO:0060370"(susceptibility to T cell mediated cytotoxicity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033318|interpro:IPR036179|rcsb pdb:3R0N|rcsb pdb:4DFH|rcsb pdb:4DFI|rcsb pdb:4HZA|rcsb pdb:5V52|reactome:R-HSA-198933|reactome:R-HSA-418990|reactome:R-HSA-420597|go:"GO:0042803"(protein homodimerization activity)|dip:DIP-41043N intact:EBI-2826725(isoform-parent)|ensembl:ENSG00000177707(gene)|ensembl:ENST00000485303(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:xGLJch8JXc+urj11GXKFPgBLYuc9606 rogid:lzSScehKhxTPj0E6EmL+P+XXjB09606 rigid:2MoijzgNZRUk313cy0s/crul6GU false sufficient binding region:32-350 sufficient binding region:58-359 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JKF6 uniprotkb:Q9JKF6 intact:EBI-7188613|ensembl:ENSMUSP00000034510|uniprotkb:Q6P9M9|intact:MINT-254710|uniprotkb:Q9JI17|uniprotkb:Q9ERL5 intact:EBI-7188613|ensembl:ENSMUSP00000034510|uniprotkb:Q6P9M9|intact:MINT-254710|uniprotkb:Q9JI17|uniprotkb:Q9ERL5 psi-mi:nect1_mouse(display_long)|uniprotkb:Nectin1(gene name)|psi-mi:Nectin1(display_short)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Hvec(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym)|uniprotkb:Prr1(gene name synonym)|uniprotkb:Pvrl1(gene name synonym) psi-mi:nect1_mouse(display_long)|uniprotkb:Nectin1(gene name)|psi-mi:Nectin1(display_short)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Hvec(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym)|uniprotkb:Prr1(gene name synonym)|uniprotkb:Pvrl1(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16007687|imex:IM-18564-1|dip:DIP-189993E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000034510(transcript)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002934"(desmosome organization)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006826"(iron ion transport)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032584"(growth cone membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070166"(enamel mineralization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033314|interpro:IPR036179|interpro:IPR041849|interpro:IPR041850|rcsb pdb:2L7J|rcsb pdb:5B21|reactome:R-MMU-418990|reactome:R-MMU-420597|ensembl:ENSMUSG00000032012(gene)|refseq:NP_067399.2|dip:DIP-41728N ensembl:ENSMUST00000034510(transcript)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002934"(desmosome organization)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006826"(iron ion transport)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032584"(growth cone membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070166"(enamel mineralization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033314|interpro:IPR036179|interpro:IPR041849|interpro:IPR041850|rcsb pdb:2L7J|rcsb pdb:5B21|reactome:R-MMU-418990|reactome:R-MMU-420597|ensembl:ENSMUSG00000032012(gene)|refseq:NP_067399.2|dip:DIP-41728N psi-mi:"MI:0465"(dip) comment:mint|function:"Probably involved in cell adhesion. Receptor for alphaherpesvirus (HSV-1, HSV-2 and pseudorabies virus) entry into cells" comment:mint|function:"Probably involved in cell adhesion. Receptor for alphaherpesvirus (HSV-1, HSV-2 and pseudorabies virus) entry into cells" full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:4HEJEu4oenwtwGXPX+gHeIfPw/810090 rogid:4HEJEu4oenwtwGXPX+gHeIfPw/810090 rigid:d7fII1G5R08lcL0Y8/KjOzW4xAo false sufficient binding region:31-337 sufficient binding region:31-337 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R007 uniprotkb:Q8R007 intact:EBI-16007862|ensembl:ENSMUSP00000006578|ensembl:ENSMUSP00000106917|uniprotkb:Q3U318|uniprotkb:Q8CED8|uniprotkb:Q9DBP8 intact:EBI-16007862|ensembl:ENSMUSP00000006578|ensembl:ENSMUSP00000106917|uniprotkb:Q3U318|uniprotkb:Q8CED8|uniprotkb:Q9DBP8 psi-mi:nect4_mouse(display_long)|uniprotkb:Nectin4(gene name)|psi-mi:Nectin4(display_short)|uniprotkb:Lnir(gene name synonym)|uniprotkb:Prr4(gene name synonym)|uniprotkb:Pvrl4(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 4(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 4(gene name synonym)|uniprotkb:Ig superfamily receptor LNIR(gene name synonym) psi-mi:nect4_mouse(display_long)|uniprotkb:Nectin4(gene name)|psi-mi:Nectin4(display_short)|uniprotkb:Lnir(gene name synonym)|uniprotkb:Prr4(gene name synonym)|uniprotkb:Pvrl4(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 4(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 4(gene name synonym)|uniprotkb:Ig superfamily receptor LNIR(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16007909|imex:IM-18564-9|dip:DIP-189996E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000006411(gene)|ensembl:ENSMUST00000006578(transcript)|ensembl:ENSMUST00000111286(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033320|interpro:IPR036179|reactome:R-MMU-418990|reactome:R-MMU-420597|interpro:IPR003599(Immunoglobulin subtype)|refseq:NP_001116152.1|refseq:NP_082169.2|dip:DIP-59965N ensembl:ENSMUSG00000006411(gene)|ensembl:ENSMUST00000006578(transcript)|ensembl:ENSMUST00000111286(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033320|interpro:IPR036179|reactome:R-MMU-418990|reactome:R-MMU-420597|interpro:IPR003599(Immunoglobulin subtype)|refseq:NP_001116152.1|refseq:NP_082169.2|dip:DIP-59965N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:h2xrWB898AEgBGv6xjeZZUTacAQ10090 rogid:h2xrWB898AEgBGv6xjeZZUTacAQ10090 rigid:M7u+n0WOPe160vpkRSIkkCiy3I4 false sufficient binding region:31-338 sufficient binding region:31-338 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96NY8 uniprotkb:Q96NY8 intact:EBI-4314784|uniprotkb:Q96K15|uniprotkb:B4DQW3|ensembl:ENSP00000356991 intact:EBI-4314784|uniprotkb:Q96K15|uniprotkb:B4DQW3|ensembl:ENSP00000356991 psi-mi:nect4_human(display_long)|uniprotkb:NECTIN4(gene name)|psi-mi:NECTIN4(display_short)|uniprotkb:Ig superfamily receptor LNIR(gene name synonym)|uniprotkb:LNIR(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 4(gene name synonym)|uniprotkb:PRR4(gene name synonym)|uniprotkb:PVRL4(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 4(gene name synonym) psi-mi:nect4_human(display_long)|uniprotkb:NECTIN4(gene name)|psi-mi:NECTIN4(display_short)|uniprotkb:Ig superfamily receptor LNIR(gene name synonym)|uniprotkb:LNIR(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 4(gene name synonym)|uniprotkb:PRR4(gene name synonym)|uniprotkb:PVRL4(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 4(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16007844|imex:IM-18564-8|dip:DIP-190000E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112178.2|ensembl:ENSG00000143217(gene)|ensembl:ENST00000368012(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033320|interpro:IPR036179|rcsb pdb:4FRW|rcsb pdb:4GJT|rcsb pdb:4JJH|reactome:R-HSA-418990|reactome:R-HSA-420597|dip:DIP-41492N refseq:NP_112178.2|ensembl:ENSG00000143217(gene)|ensembl:ENST00000368012(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033320|interpro:IPR036179|rcsb pdb:4FRW|rcsb pdb:4GJT|rcsb pdb:4JJH|reactome:R-HSA-418990|reactome:R-HSA-420597|dip:DIP-41492N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:xh33OK0Z4RsYD8uJZYbmnGfs/TQ9606 rogid:xh33OK0Z4RsYD8uJZYbmnGfs/TQ9606 rigid:muU+QDfyskLZe6PG/jfSHpXo5OU false sufficient binding region:32-243 sufficient binding region:32-243 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JLB9-1 uniprotkb:Q9JLB9-1 intact:EBI-16007816|ensembl:ENSMUSP00000023334 intact:EBI-16007816|ensembl:ENSMUSP00000023334 psi-mi:q9jlb9-1(display_long)|uniprotkb:Nectin3(gene name)|psi-mi:Nectin3(display_short)|uniprotkb:Pvrl3(gene name synonym)|uniprotkb:Nectin-3 alpha(isoform synonym)|uniprotkb:Nectin cell adhesion molecule 3(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 3(gene name synonym) psi-mi:q9jlb9-1(display_long)|uniprotkb:Nectin3(gene name)|psi-mi:Nectin3(display_short)|uniprotkb:Pvrl3(gene name synonym)|uniprotkb:Nectin-3 alpha(isoform synonym)|uniprotkb:Nectin cell adhesion molecule 3(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 3(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16007825|imex:IM-18564-7|dip:DIP-189995E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-4306755(isoform-parent)|ensembl:ENSMUSG00000022656(gene)|ensembl:ENSMUST00000023334(transcript) intact:EBI-4306755(isoform-parent)|ensembl:ENSMUSG00000022656(gene)|ensembl:ENSMUST00000023334(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:hF88tJa0izs2SsJboxVJUyuKRfE10090 rogid:hF88tJa0izs2SsJboxVJUyuKRfE10090 rigid:1zZQFoeqvqJSyKkl6TqfrtpTk14 false sufficient binding region:58-401 sufficient binding region:58-401 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92692 uniprotkb:Q9NQS3-1 intact:EBI-718419|uniprotkb:A8K5L5|uniprotkb:O75455|uniprotkb:Q96J29|uniprotkb:Q6IBI6|ensembl:ENSP00000252483 intact:EBI-16007706|ensembl:ENSP00000418070 psi-mi:nect2_human(display_long)|uniprotkb:NECTIN2(gene name)|psi-mi:NECTIN2(display_short)|uniprotkb:HVEB(gene name synonym)|uniprotkb:Herpes virus entry mediator B(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 2(gene name synonym)|uniprotkb:PRR2(gene name synonym)|uniprotkb:PVRL2(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 2(gene name synonym) psi-mi:q9nqs3-1(display_long)|uniprotkb:NECTIN3(gene name)|psi-mi:NECTIN3(display_short)|uniprotkb:PRR3(gene name synonym)|uniprotkb:PVRL3(gene name synonym)|uniprotkb:CDw113(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 3(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 3(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16007795|imex:IM-18564-6|dip:DIP-190003E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036189.1|refseq:NP_002847.1|ensembl:ENSG00000130202(gene)|ensembl:ENST00000252483(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001675"(acrosome assembly)|go:"GO:0002860"(positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:"GO:0002891"(positive regulation of immunoglobulin mediated immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007286"(spermatid development)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0009566"(fertilization)|go:"GO:0009986"(cell surface)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0030382"(sperm mitochondrion organization)|go:"GO:0032990"(cell part morphogenesis)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0042271"(susceptibility to natural killer cell mediated cytotoxicity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044406"(adhesion of symbiont to host)|go:"GO:0044782"(cilium organization)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046814"(coreceptor-mediated virion attachment to host cell)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051654"(establishment of mitochondrion localization)|go:"GO:0060370"(susceptibility to T cell mediated cytotoxicity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033318|interpro:IPR036179|rcsb pdb:3R0N|rcsb pdb:4DFH|rcsb pdb:4DFI|rcsb pdb:4HZA|rcsb pdb:5V52|reactome:R-HSA-198933|reactome:R-HSA-418990|reactome:R-HSA-420597|go:"GO:0042803"(protein homodimerization activity)|dip:DIP-41043N intact:EBI-2826725(isoform-parent)|ensembl:ENSG00000177707(gene)|ensembl:ENST00000485303(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:xGLJch8JXc+urj11GXKFPgBLYuc9606 rogid:lzSScehKhxTPj0E6EmL+P+XXjB09606 rigid:2MoijzgNZRUk313cy0s/crul6GU false sufficient binding region:32-350 sufficient binding region:58-359 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NQS3-1 uniprotkb:Q9NQS3-1 intact:EBI-16007706|ensembl:ENSP00000418070 intact:EBI-16007706|ensembl:ENSP00000418070 psi-mi:q9nqs3-1(display_long)|uniprotkb:NECTIN3(gene name)|psi-mi:NECTIN3(display_short)|uniprotkb:PRR3(gene name synonym)|uniprotkb:PVRL3(gene name synonym)|uniprotkb:CDw113(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 3(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 3(gene name synonym) psi-mi:q9nqs3-1(display_long)|uniprotkb:NECTIN3(gene name)|psi-mi:NECTIN3(display_short)|uniprotkb:PRR3(gene name synonym)|uniprotkb:PVRL3(gene name synonym)|uniprotkb:CDw113(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 3(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 3(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16007927|imex:IM-18564-10|dip:DIP-189999E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2826725(isoform-parent)|ensembl:ENSG00000177707(gene)|ensembl:ENST00000485303(transcript) intact:EBI-2826725(isoform-parent)|ensembl:ENSG00000177707(gene)|ensembl:ENST00000485303(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:lzSScehKhxTPj0E6EmL+P+XXjB09606 rogid:lzSScehKhxTPj0E6EmL+P+XXjB09606 rigid:UIQ+zYWzBNy4ZkKbVVnFpORHJes false sufficient binding region:58-359 sufficient binding region:58-359 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32507-2 uniprotkb:P32507-2 intact:EBI-8844104|ensembl:ENSMUSP00000104089 intact:EBI-8844104|ensembl:ENSMUSP00000104089 psi-mi:p32507-2(display_long)|uniprotkb:Nectin2(gene name)|psi-mi:Nectin2(display_short)|uniprotkb:Herpes virus entry mediator B(gene name synonym)|uniprotkb:Mph(gene name synonym)|uniprotkb:Murine herpes virus entry protein B(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 2(gene name synonym)|uniprotkb:Poliovirus receptor homolog(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 2(gene name synonym)|uniprotkb:Pvr(gene name synonym)|uniprotkb:Pvrl2(gene name synonym)|uniprotkb:Pvs(gene name synonym) psi-mi:p32507-2(display_long)|uniprotkb:Nectin2(gene name)|psi-mi:Nectin2(display_short)|uniprotkb:Herpes virus entry mediator B(gene name synonym)|uniprotkb:Mph(gene name synonym)|uniprotkb:Murine herpes virus entry protein B(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 2(gene name synonym)|uniprotkb:Poliovirus receptor homolog(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 2(gene name synonym)|uniprotkb:Pvr(gene name synonym)|uniprotkb:Pvrl2(gene name synonym)|uniprotkb:Pvs(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16007774|imex:IM-18564-5|dip:DIP-189994E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8758399(isoform-parent)|ensembl:ENSMUSG00000062300(gene)|ensembl:ENSMUST00000108450(transcript) intact:EBI-8758399(isoform-parent)|ensembl:ENSMUSG00000062300(gene)|ensembl:ENSMUST00000108450(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:fCuDZiVCuP5zAS8IxPjZBMERkYs10090 rogid:fCuDZiVCuP5zAS8IxPjZBMERkYs10090 rigid:tXDc2wT7KTD9PcTwZzGHMGkekUc false sufficient binding region:32-250|mutation disrupting interaction strength:136-136 sufficient binding region:32-250|mutation disrupting interaction strength:136-136 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15223 uniprotkb:Q9NQS3-1 intact:EBI-1771314|uniprotkb:O75465|uniprotkb:Q2M3D3|uniprotkb:Q9HBE6|uniprotkb:Q9HBW2|ensembl:ENSP00000264025 intact:EBI-16007706|ensembl:ENSP00000418070 psi-mi:nect1_human(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Herpesvirus Ig-like receptor(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:q9nqs3-1(display_long)|uniprotkb:NECTIN3(gene name)|psi-mi:NECTIN3(display_short)|uniprotkb:PRR3(gene name synonym)|uniprotkb:PVRL3(gene name synonym)|uniprotkb:CDw113(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 3(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 3(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16007948|imex:IM-18564-11|dip:DIP-70527E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002846.3|refseq:NP_976030.1|refseq:NP_976031.1|dip:DIP-40302N|ensembl:ENSG00000110400(gene)|ensembl:ENST00000264025(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002934"(desmosome organization)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070166"(enamel mineralization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033314|interpro:IPR036179|interpro:IPR041849|interpro:IPR041850|rcsb pdb:3ALP|rcsb pdb:3SKU|rcsb pdb:3U82|rcsb pdb:3U83|rcsb pdb:4FMF|rcsb pdb:4MYW|reactome:R-HSA-418990|reactome:R-HSA-420597 intact:EBI-2826725(isoform-parent)|ensembl:ENSG00000177707(gene)|ensembl:ENST00000485303(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:/KqZN5Vhyc6Qrih7IyHnkN8nsaE9606 rogid:lzSScehKhxTPj0E6EmL+P+XXjB09606 rigid:cdl/8sOs9TPvDFm+TMyCSPkuSHw false sufficient binding region:31-337|mutation disrupting interaction strength:129-129 sufficient binding region:58-359 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32507-2 uniprotkb:P32507-2 intact:EBI-8844104|ensembl:ENSMUSP00000104089 intact:EBI-8844104|ensembl:ENSMUSP00000104089 psi-mi:p32507-2(display_long)|uniprotkb:Nectin2(gene name)|psi-mi:Nectin2(display_short)|uniprotkb:Herpes virus entry mediator B(gene name synonym)|uniprotkb:Mph(gene name synonym)|uniprotkb:Murine herpes virus entry protein B(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 2(gene name synonym)|uniprotkb:Poliovirus receptor homolog(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 2(gene name synonym)|uniprotkb:Pvr(gene name synonym)|uniprotkb:Pvrl2(gene name synonym)|uniprotkb:Pvs(gene name synonym) psi-mi:p32507-2(display_long)|uniprotkb:Nectin2(gene name)|psi-mi:Nectin2(display_short)|uniprotkb:Herpes virus entry mediator B(gene name synonym)|uniprotkb:Mph(gene name synonym)|uniprotkb:Murine herpes virus entry protein B(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 2(gene name synonym)|uniprotkb:Poliovirus receptor homolog(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 2(gene name synonym)|uniprotkb:Pvr(gene name synonym)|uniprotkb:Pvrl2(gene name synonym)|uniprotkb:Pvs(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16007974|imex:IM-18564-12|dip:DIP-189994E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8758399(isoform-parent)|ensembl:ENSMUSG00000062300(gene)|ensembl:ENSMUST00000108450(transcript) intact:EBI-8758399(isoform-parent)|ensembl:ENSMUSG00000062300(gene)|ensembl:ENSMUST00000108450(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:fCuDZiVCuP5zAS8IxPjZBMERkYs10090 rogid:fCuDZiVCuP5zAS8IxPjZBMERkYs10090 rigid:tXDc2wT7KTD9PcTwZzGHMGkekUc false mutation disrupting interaction strength:136-136|sufficient binding region:32-250 mutation disrupting interaction strength:136-136|sufficient binding region:32-250 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15223 uniprotkb:Q15223 intact:EBI-1771314|uniprotkb:O75465|uniprotkb:Q2M3D3|uniprotkb:Q9HBE6|uniprotkb:Q9HBW2|ensembl:ENSP00000264025 intact:EBI-1771314|uniprotkb:O75465|uniprotkb:Q2M3D3|uniprotkb:Q9HBE6|uniprotkb:Q9HBW2|ensembl:ENSP00000264025 psi-mi:nect1_human(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Herpesvirus Ig-like receptor(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:nect1_human(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Herpesvirus Ig-like receptor(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16008037|imex:IM-18564-15|dip:DIP-189997E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002846.3|refseq:NP_976030.1|refseq:NP_976031.1|dip:DIP-40302N|ensembl:ENSG00000110400(gene)|ensembl:ENST00000264025(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002934"(desmosome organization)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070166"(enamel mineralization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033314|interpro:IPR036179|interpro:IPR041849|interpro:IPR041850|rcsb pdb:3ALP|rcsb pdb:3SKU|rcsb pdb:3U82|rcsb pdb:3U83|rcsb pdb:4FMF|rcsb pdb:4MYW|reactome:R-HSA-418990|reactome:R-HSA-420597 refseq:NP_002846.3|refseq:NP_976030.1|refseq:NP_976031.1|dip:DIP-40302N|ensembl:ENSG00000110400(gene)|ensembl:ENST00000264025(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002934"(desmosome organization)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070166"(enamel mineralization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033314|interpro:IPR036179|interpro:IPR041849|interpro:IPR041850|rcsb pdb:3ALP|rcsb pdb:3SKU|rcsb pdb:3U82|rcsb pdb:3U83|rcsb pdb:4FMF|rcsb pdb:4MYW|reactome:R-HSA-418990|reactome:R-HSA-420597 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:/KqZN5Vhyc6Qrih7IyHnkN8nsaE9606 rogid:/KqZN5Vhyc6Qrih7IyHnkN8nsaE9606 rigid:NCMYoD0Gz5GbeGtahYjJIXHOcaQ false sufficient binding region:31-337|mutation decreasing interaction strength:129-129 sufficient binding region:31-337|mutation decreasing interaction strength:129-129 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15223 uniprotkb:Q9NQS3-1 intact:EBI-1771314|uniprotkb:O75465|uniprotkb:Q2M3D3|uniprotkb:Q9HBE6|uniprotkb:Q9HBW2|ensembl:ENSP00000264025 intact:EBI-16007706|ensembl:ENSP00000418070 psi-mi:nect1_human(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Herpesvirus Ig-like receptor(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:q9nqs3-1(display_long)|uniprotkb:NECTIN3(gene name)|psi-mi:NECTIN3(display_short)|uniprotkb:PRR3(gene name synonym)|uniprotkb:PVRL3(gene name synonym)|uniprotkb:CDw113(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 3(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 3(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16008016|imex:IM-18564-14|dip:DIP-70527E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002846.3|refseq:NP_976030.1|refseq:NP_976031.1|dip:DIP-40302N|ensembl:ENSG00000110400(gene)|ensembl:ENST00000264025(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002934"(desmosome organization)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070166"(enamel mineralization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033314|interpro:IPR036179|interpro:IPR041849|interpro:IPR041850|rcsb pdb:3ALP|rcsb pdb:3SKU|rcsb pdb:3U82|rcsb pdb:3U83|rcsb pdb:4FMF|rcsb pdb:4MYW|reactome:R-HSA-418990|reactome:R-HSA-420597 intact:EBI-2826725(isoform-parent)|ensembl:ENSG00000177707(gene)|ensembl:ENST00000485303(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:/KqZN5Vhyc6Qrih7IyHnkN8nsaE9606 rogid:lzSScehKhxTPj0E6EmL+P+XXjB09606 rigid:cdl/8sOs9TPvDFm+TMyCSPkuSHw false sufficient binding region:31-337 sufficient binding region:58-359 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92692 uniprotkb:Q92692 intact:EBI-718419|uniprotkb:A8K5L5|uniprotkb:O75455|uniprotkb:Q96J29|uniprotkb:Q6IBI6|ensembl:ENSP00000252483 intact:EBI-718419|uniprotkb:A8K5L5|uniprotkb:O75455|uniprotkb:Q96J29|uniprotkb:Q6IBI6|ensembl:ENSP00000252483 psi-mi:nect2_human(display_long)|uniprotkb:NECTIN2(gene name)|psi-mi:NECTIN2(display_short)|uniprotkb:HVEB(gene name synonym)|uniprotkb:Herpes virus entry mediator B(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 2(gene name synonym)|uniprotkb:PRR2(gene name synonym)|uniprotkb:PVRL2(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 2(gene name synonym) psi-mi:nect2_human(display_long)|uniprotkb:NECTIN2(gene name)|psi-mi:NECTIN2(display_short)|uniprotkb:HVEB(gene name synonym)|uniprotkb:Herpes virus entry mediator B(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 2(gene name synonym)|uniprotkb:PRR2(gene name synonym)|uniprotkb:PVRL2(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 2(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16007995|imex:IM-18564-13|dip:DIP-189998E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036189.1|refseq:NP_002847.1|ensembl:ENSG00000130202(gene)|ensembl:ENST00000252483(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001675"(acrosome assembly)|go:"GO:0002860"(positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:"GO:0002891"(positive regulation of immunoglobulin mediated immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007286"(spermatid development)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0009566"(fertilization)|go:"GO:0009986"(cell surface)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0030382"(sperm mitochondrion organization)|go:"GO:0032990"(cell part morphogenesis)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0042271"(susceptibility to natural killer cell mediated cytotoxicity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044406"(adhesion of symbiont to host)|go:"GO:0044782"(cilium organization)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046814"(coreceptor-mediated virion attachment to host cell)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051654"(establishment of mitochondrion localization)|go:"GO:0060370"(susceptibility to T cell mediated cytotoxicity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033318|interpro:IPR036179|rcsb pdb:3R0N|rcsb pdb:4DFH|rcsb pdb:4DFI|rcsb pdb:4HZA|rcsb pdb:5V52|reactome:R-HSA-198933|reactome:R-HSA-418990|reactome:R-HSA-420597|go:"GO:0042803"(protein homodimerization activity)|dip:DIP-41043N refseq:NP_001036189.1|refseq:NP_002847.1|ensembl:ENSG00000130202(gene)|ensembl:ENST00000252483(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001675"(acrosome assembly)|go:"GO:0002860"(positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:"GO:0002891"(positive regulation of immunoglobulin mediated immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007286"(spermatid development)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0009566"(fertilization)|go:"GO:0009986"(cell surface)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0030382"(sperm mitochondrion organization)|go:"GO:0032990"(cell part morphogenesis)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0042271"(susceptibility to natural killer cell mediated cytotoxicity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044406"(adhesion of symbiont to host)|go:"GO:0044782"(cilium organization)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046814"(coreceptor-mediated virion attachment to host cell)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051654"(establishment of mitochondrion localization)|go:"GO:0060370"(susceptibility to T cell mediated cytotoxicity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033318|interpro:IPR036179|rcsb pdb:3R0N|rcsb pdb:4DFH|rcsb pdb:4DFI|rcsb pdb:4HZA|rcsb pdb:5V52|reactome:R-HSA-198933|reactome:R-HSA-418990|reactome:R-HSA-420597|go:"GO:0042803"(protein homodimerization activity)|dip:DIP-41043N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:xGLJch8JXc+urj11GXKFPgBLYuc9606 rogid:xGLJch8JXc+urj11GXKFPgBLYuc9606 rigid:fbKgdsL+oGRVlBLBpGVQqQJ0vAw false sufficient binding region:32-350 sufficient binding region:32-350 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92692 uniprotkb:Q92692 intact:EBI-718419|uniprotkb:A8K5L5|uniprotkb:O75455|uniprotkb:Q96J29|uniprotkb:Q6IBI6|ensembl:ENSP00000252483 intact:EBI-718419|uniprotkb:A8K5L5|uniprotkb:O75455|uniprotkb:Q96J29|uniprotkb:Q6IBI6|ensembl:ENSP00000252483 psi-mi:nect2_human(display_long)|uniprotkb:NECTIN2(gene name)|psi-mi:NECTIN2(display_short)|uniprotkb:HVEB(gene name synonym)|uniprotkb:Herpes virus entry mediator B(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 2(gene name synonym)|uniprotkb:PRR2(gene name synonym)|uniprotkb:PVRL2(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 2(gene name synonym) psi-mi:nect2_human(display_long)|uniprotkb:NECTIN2(gene name)|psi-mi:NECTIN2(display_short)|uniprotkb:HVEB(gene name synonym)|uniprotkb:Herpes virus entry mediator B(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 2(gene name synonym)|uniprotkb:PRR2(gene name synonym)|uniprotkb:PVRL2(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 2(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16008057|imex:IM-18564-16|dip:DIP-189998E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036189.1|refseq:NP_002847.1|ensembl:ENSG00000130202(gene)|ensembl:ENST00000252483(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001675"(acrosome assembly)|go:"GO:0002860"(positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:"GO:0002891"(positive regulation of immunoglobulin mediated immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007286"(spermatid development)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0009566"(fertilization)|go:"GO:0009986"(cell surface)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0030382"(sperm mitochondrion organization)|go:"GO:0032990"(cell part morphogenesis)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0042271"(susceptibility to natural killer cell mediated cytotoxicity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044406"(adhesion of symbiont to host)|go:"GO:0044782"(cilium organization)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046814"(coreceptor-mediated virion attachment to host cell)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051654"(establishment of mitochondrion localization)|go:"GO:0060370"(susceptibility to T cell mediated cytotoxicity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033318|interpro:IPR036179|rcsb pdb:3R0N|rcsb pdb:4DFH|rcsb pdb:4DFI|rcsb pdb:4HZA|rcsb pdb:5V52|reactome:R-HSA-198933|reactome:R-HSA-418990|reactome:R-HSA-420597|go:"GO:0042803"(protein homodimerization activity)|dip:DIP-41043N refseq:NP_001036189.1|refseq:NP_002847.1|ensembl:ENSG00000130202(gene)|ensembl:ENST00000252483(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001675"(acrosome assembly)|go:"GO:0002860"(positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:"GO:0002891"(positive regulation of immunoglobulin mediated immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007286"(spermatid development)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0009566"(fertilization)|go:"GO:0009986"(cell surface)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0030382"(sperm mitochondrion organization)|go:"GO:0032990"(cell part morphogenesis)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0042271"(susceptibility to natural killer cell mediated cytotoxicity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044406"(adhesion of symbiont to host)|go:"GO:0044782"(cilium organization)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046814"(coreceptor-mediated virion attachment to host cell)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051654"(establishment of mitochondrion localization)|go:"GO:0060370"(susceptibility to T cell mediated cytotoxicity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033318|interpro:IPR036179|rcsb pdb:3R0N|rcsb pdb:4DFH|rcsb pdb:4DFI|rcsb pdb:4HZA|rcsb pdb:5V52|reactome:R-HSA-198933|reactome:R-HSA-418990|reactome:R-HSA-420597|go:"GO:0042803"(protein homodimerization activity)|dip:DIP-41043N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:xGLJch8JXc+urj11GXKFPgBLYuc9606 rogid:xGLJch8JXc+urj11GXKFPgBLYuc9606 rigid:PCjL5OEVHPZsW/R5j/2sRzD0grM false sufficient binding region:32-350 sufficient binding region:32-350 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96NY8 uniprotkb:Q96NY8 intact:EBI-4314784|uniprotkb:Q96K15|uniprotkb:B4DQW3|ensembl:ENSP00000356991 intact:EBI-4314784|uniprotkb:Q96K15|uniprotkb:B4DQW3|ensembl:ENSP00000356991 psi-mi:nect4_human(display_long)|uniprotkb:NECTIN4(gene name)|psi-mi:NECTIN4(display_short)|uniprotkb:Ig superfamily receptor LNIR(gene name synonym)|uniprotkb:LNIR(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 4(gene name synonym)|uniprotkb:PRR4(gene name synonym)|uniprotkb:PVRL4(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 4(gene name synonym) psi-mi:nect4_human(display_long)|uniprotkb:NECTIN4(gene name)|psi-mi:NECTIN4(display_short)|uniprotkb:Ig superfamily receptor LNIR(gene name synonym)|uniprotkb:LNIR(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 4(gene name synonym)|uniprotkb:PRR4(gene name synonym)|uniprotkb:PVRL4(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 4(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16008075|imex:IM-18564-17|dip:DIP-190000E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112178.2|ensembl:ENSG00000143217(gene)|ensembl:ENST00000368012(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033320|interpro:IPR036179|rcsb pdb:4FRW|rcsb pdb:4GJT|rcsb pdb:4JJH|reactome:R-HSA-418990|reactome:R-HSA-420597|dip:DIP-41492N refseq:NP_112178.2|ensembl:ENSG00000143217(gene)|ensembl:ENST00000368012(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033320|interpro:IPR036179|rcsb pdb:4FRW|rcsb pdb:4GJT|rcsb pdb:4JJH|reactome:R-HSA-418990|reactome:R-HSA-420597|dip:DIP-41492N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:xh33OK0Z4RsYD8uJZYbmnGfs/TQ9606 rogid:xh33OK0Z4RsYD8uJZYbmnGfs/TQ9606 rigid:c4oY8ZtvJmf3xDJpel5L4wAYdAY false sufficient binding region:32-336 sufficient binding region:32-336 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NQS3-1 uniprotkb:Q9NQS3-1 intact:EBI-16007706|ensembl:ENSP00000418070 intact:EBI-16007706|ensembl:ENSP00000418070 psi-mi:q9nqs3-1(display_long)|uniprotkb:NECTIN3(gene name)|psi-mi:NECTIN3(display_short)|uniprotkb:PRR3(gene name synonym)|uniprotkb:PVRL3(gene name synonym)|uniprotkb:CDw113(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 3(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 3(gene name synonym) psi-mi:q9nqs3-1(display_long)|uniprotkb:NECTIN3(gene name)|psi-mi:NECTIN3(display_short)|uniprotkb:PRR3(gene name synonym)|uniprotkb:PVRL3(gene name synonym)|uniprotkb:CDw113(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 3(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 3(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16008096|imex:IM-18564-18|dip:DIP-189999E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2826725(isoform-parent)|ensembl:ENSG00000177707(gene)|ensembl:ENST00000485303(transcript) intact:EBI-2826725(isoform-parent)|ensembl:ENSG00000177707(gene)|ensembl:ENST00000485303(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:lzSScehKhxTPj0E6EmL+P+XXjB09606 rogid:lzSScehKhxTPj0E6EmL+P+XXjB09606 rigid:vvFx2Jc6qAm+z7hL6XHnIXgJf4g false sufficient binding region:58-359 sufficient binding region:58-359 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96NY8 uniprotkb:Q15223 intact:EBI-4314784|uniprotkb:Q96K15|uniprotkb:B4DQW3|ensembl:ENSP00000356991 intact:EBI-1771314|uniprotkb:O75465|uniprotkb:Q2M3D3|uniprotkb:Q9HBE6|uniprotkb:Q9HBW2|ensembl:ENSP00000264025 psi-mi:nect4_human(display_long)|uniprotkb:NECTIN4(gene name)|psi-mi:NECTIN4(display_short)|uniprotkb:Ig superfamily receptor LNIR(gene name synonym)|uniprotkb:LNIR(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 4(gene name synonym)|uniprotkb:PRR4(gene name synonym)|uniprotkb:PVRL4(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 4(gene name synonym) psi-mi:nect1_human(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Herpesvirus Ig-like receptor(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16008114|imex:IM-18564-19|dip:DIP-70528E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112178.2|ensembl:ENSG00000143217(gene)|ensembl:ENST00000368012(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033320|interpro:IPR036179|rcsb pdb:4FRW|rcsb pdb:4GJT|rcsb pdb:4JJH|reactome:R-HSA-418990|reactome:R-HSA-420597|dip:DIP-41492N refseq:NP_002846.3|refseq:NP_976030.1|refseq:NP_976031.1|dip:DIP-40302N|ensembl:ENSG00000110400(gene)|ensembl:ENST00000264025(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002934"(desmosome organization)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070166"(enamel mineralization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033314|interpro:IPR036179|interpro:IPR041849|interpro:IPR041850|rcsb pdb:3ALP|rcsb pdb:3SKU|rcsb pdb:3U82|rcsb pdb:3U83|rcsb pdb:4FMF|rcsb pdb:4MYW|reactome:R-HSA-418990|reactome:R-HSA-420597 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:xh33OK0Z4RsYD8uJZYbmnGfs/TQ9606 rogid:/KqZN5Vhyc6Qrih7IyHnkN8nsaE9606 rigid:hRMxaFNfMrQX1Np++7ViMPL0jdQ false sufficient binding region:32-336 sufficient binding region:31-337|mutation disrupting interaction strength:129-129 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15223 uniprotkb:Q15223 intact:EBI-1771314|uniprotkb:O75465|uniprotkb:Q2M3D3|uniprotkb:Q9HBE6|uniprotkb:Q9HBW2|ensembl:ENSP00000264025 intact:EBI-1771314|uniprotkb:O75465|uniprotkb:Q2M3D3|uniprotkb:Q9HBE6|uniprotkb:Q9HBW2|ensembl:ENSP00000264025 psi-mi:nect1_human(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Herpesvirus Ig-like receptor(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:nect1_human(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Herpesvirus Ig-like receptor(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16008137|imex:IM-18564-20|dip:DIP-189997E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002846.3|refseq:NP_976030.1|refseq:NP_976031.1|dip:DIP-40302N|ensembl:ENSG00000110400(gene)|ensembl:ENST00000264025(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002934"(desmosome organization)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070166"(enamel mineralization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033314|interpro:IPR036179|interpro:IPR041849|interpro:IPR041850|rcsb pdb:3ALP|rcsb pdb:3SKU|rcsb pdb:3U82|rcsb pdb:3U83|rcsb pdb:4FMF|rcsb pdb:4MYW|reactome:R-HSA-418990|reactome:R-HSA-420597 refseq:NP_002846.3|refseq:NP_976030.1|refseq:NP_976031.1|dip:DIP-40302N|ensembl:ENSG00000110400(gene)|ensembl:ENST00000264025(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002934"(desmosome organization)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070166"(enamel mineralization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033314|interpro:IPR036179|interpro:IPR041849|interpro:IPR041850|rcsb pdb:3ALP|rcsb pdb:3SKU|rcsb pdb:3U82|rcsb pdb:3U83|rcsb pdb:4FMF|rcsb pdb:4MYW|reactome:R-HSA-418990|reactome:R-HSA-420597 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:/KqZN5Vhyc6Qrih7IyHnkN8nsaE9606 rogid:/KqZN5Vhyc6Qrih7IyHnkN8nsaE9606 rigid:U5T4eog3v1KBYDTHgqG9QujW/RA false sufficient binding region:31-337 sufficient binding region:31-337 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96NY8 uniprotkb:Q96NY8 intact:EBI-4314784|uniprotkb:Q96K15|uniprotkb:B4DQW3|ensembl:ENSP00000356991 intact:EBI-4314784|uniprotkb:Q96K15|uniprotkb:B4DQW3|ensembl:ENSP00000356991 psi-mi:nect4_human(display_long)|uniprotkb:NECTIN4(gene name)|psi-mi:NECTIN4(display_short)|uniprotkb:Ig superfamily receptor LNIR(gene name synonym)|uniprotkb:LNIR(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 4(gene name synonym)|uniprotkb:PRR4(gene name synonym)|uniprotkb:PVRL4(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 4(gene name synonym) psi-mi:nect4_human(display_long)|uniprotkb:NECTIN4(gene name)|psi-mi:NECTIN4(display_short)|uniprotkb:Ig superfamily receptor LNIR(gene name synonym)|uniprotkb:LNIR(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 4(gene name synonym)|uniprotkb:PRR4(gene name synonym)|uniprotkb:PVRL4(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 4(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16008179|imex:IM-18564-22|dip:DIP-190000E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112178.2|ensembl:ENSG00000143217(gene)|ensembl:ENST00000368012(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033320|interpro:IPR036179|rcsb pdb:4FRW|rcsb pdb:4GJT|rcsb pdb:4JJH|reactome:R-HSA-418990|reactome:R-HSA-420597|dip:DIP-41492N refseq:NP_112178.2|ensembl:ENSG00000143217(gene)|ensembl:ENST00000368012(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033320|interpro:IPR036179|rcsb pdb:4FRW|rcsb pdb:4GJT|rcsb pdb:4JJH|reactome:R-HSA-418990|reactome:R-HSA-420597|dip:DIP-41492N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:xh33OK0Z4RsYD8uJZYbmnGfs/TQ9606 rogid:xh33OK0Z4RsYD8uJZYbmnGfs/TQ9606 rigid:muU+QDfyskLZe6PG/jfSHpXo5OU false sufficient binding region:32-336 sufficient binding region:32-336 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96NY8 uniprotkb:Q15223 intact:EBI-4314784|uniprotkb:Q96K15|uniprotkb:B4DQW3|ensembl:ENSP00000356991 intact:EBI-1771314|uniprotkb:O75465|uniprotkb:Q2M3D3|uniprotkb:Q9HBE6|uniprotkb:Q9HBW2|ensembl:ENSP00000264025 psi-mi:nect4_human(display_long)|uniprotkb:NECTIN4(gene name)|psi-mi:NECTIN4(display_short)|uniprotkb:Ig superfamily receptor LNIR(gene name synonym)|uniprotkb:LNIR(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 4(gene name synonym)|uniprotkb:PRR4(gene name synonym)|uniprotkb:PVRL4(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 4(gene name synonym) psi-mi:nect1_human(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Herpesvirus Ig-like receptor(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16008158|imex:IM-18564-21|dip:DIP-70528E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112178.2|ensembl:ENSG00000143217(gene)|ensembl:ENST00000368012(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033320|interpro:IPR036179|rcsb pdb:4FRW|rcsb pdb:4GJT|rcsb pdb:4JJH|reactome:R-HSA-418990|reactome:R-HSA-420597|dip:DIP-41492N refseq:NP_002846.3|refseq:NP_976030.1|refseq:NP_976031.1|dip:DIP-40302N|ensembl:ENSG00000110400(gene)|ensembl:ENST00000264025(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002934"(desmosome organization)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070166"(enamel mineralization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033314|interpro:IPR036179|interpro:IPR041849|interpro:IPR041850|rcsb pdb:3ALP|rcsb pdb:3SKU|rcsb pdb:3U82|rcsb pdb:3U83|rcsb pdb:4FMF|rcsb pdb:4MYW|reactome:R-HSA-418990|reactome:R-HSA-420597 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:xh33OK0Z4RsYD8uJZYbmnGfs/TQ9606 rogid:/KqZN5Vhyc6Qrih7IyHnkN8nsaE9606 rigid:hRMxaFNfMrQX1Np++7ViMPL0jdQ false sufficient binding region:32-336 sufficient binding region:31-337 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15223 uniprotkb:Q9NQS3-1 intact:EBI-1771314|uniprotkb:O75465|uniprotkb:Q2M3D3|uniprotkb:Q9HBE6|uniprotkb:Q9HBW2|ensembl:ENSP00000264025 intact:EBI-16007706|ensembl:ENSP00000418070 psi-mi:nect1_human(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Herpesvirus Ig-like receptor(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:q9nqs3-1(display_long)|uniprotkb:NECTIN3(gene name)|psi-mi:NECTIN3(display_short)|uniprotkb:PRR3(gene name synonym)|uniprotkb:PVRL3(gene name synonym)|uniprotkb:CDw113(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 3(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 3(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16008197|imex:IM-18564-23|dip:DIP-70527E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002846.3|refseq:NP_976030.1|refseq:NP_976031.1|dip:DIP-40302N|ensembl:ENSG00000110400(gene)|ensembl:ENST00000264025(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002934"(desmosome organization)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070166"(enamel mineralization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033314|interpro:IPR036179|interpro:IPR041849|interpro:IPR041850|rcsb pdb:3ALP|rcsb pdb:3SKU|rcsb pdb:3U82|rcsb pdb:3U83|rcsb pdb:4FMF|rcsb pdb:4MYW|reactome:R-HSA-418990|reactome:R-HSA-420597 intact:EBI-2826725(isoform-parent)|ensembl:ENSG00000177707(gene)|ensembl:ENST00000485303(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:/KqZN5Vhyc6Qrih7IyHnkN8nsaE9606 rogid:lzSScehKhxTPj0E6EmL+P+XXjB09606 rigid:cdl/8sOs9TPvDFm+TMyCSPkuSHw false sufficient binding region:31-337 sufficient binding region:58-359 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32507-2 uniprotkb:P32507-2 intact:EBI-8844104|ensembl:ENSMUSP00000104089 intact:EBI-8844104|ensembl:ENSMUSP00000104089 psi-mi:p32507-2(display_long)|uniprotkb:Nectin2(gene name)|psi-mi:Nectin2(display_short)|uniprotkb:Herpes virus entry mediator B(gene name synonym)|uniprotkb:Mph(gene name synonym)|uniprotkb:Murine herpes virus entry protein B(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 2(gene name synonym)|uniprotkb:Poliovirus receptor homolog(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 2(gene name synonym)|uniprotkb:Pvr(gene name synonym)|uniprotkb:Pvrl2(gene name synonym)|uniprotkb:Pvs(gene name synonym) psi-mi:p32507-2(display_long)|uniprotkb:Nectin2(gene name)|psi-mi:Nectin2(display_short)|uniprotkb:Herpes virus entry mediator B(gene name synonym)|uniprotkb:Mph(gene name synonym)|uniprotkb:Murine herpes virus entry protein B(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 2(gene name synonym)|uniprotkb:Poliovirus receptor homolog(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 2(gene name synonym)|uniprotkb:Pvr(gene name synonym)|uniprotkb:Pvrl2(gene name synonym)|uniprotkb:Pvs(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16008239|imex:IM-18564-25|dip:DIP-189994E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8758399(isoform-parent)|ensembl:ENSMUSG00000062300(gene)|ensembl:ENSMUST00000108450(transcript) intact:EBI-8758399(isoform-parent)|ensembl:ENSMUSG00000062300(gene)|ensembl:ENSMUST00000108450(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:fCuDZiVCuP5zAS8IxPjZBMERkYs10090 rogid:fCuDZiVCuP5zAS8IxPjZBMERkYs10090 rigid:Z8XC4g0kHjDH4r3CVMHTS1nMplY false myc tag:?-?|mutation:72-72 flag tag:?-?|mutation:72-72 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q15223 uniprotkb:P15151 intact:EBI-1771314|uniprotkb:O75465|uniprotkb:Q2M3D3|uniprotkb:Q9HBE6|uniprotkb:Q9HBW2|ensembl:ENSP00000264025 intact:EBI-3919694|uniprotkb:Q96BJ1|uniprotkb:Q15268|uniprotkb:Q15267|uniprotkb:P15152|uniprotkb:B4DTS9 psi-mi:nect1_human(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Herpesvirus Ig-like receptor(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:pvr_human(display_long)|uniprotkb:PVR(gene name)|psi-mi:PVR(display_short)|uniprotkb:PVS(gene name synonym)|uniprotkb:Nectin-like protein 5(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16008218|imex:IM-18564-24|dip:DIP-190001E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002846.3|refseq:NP_976030.1|refseq:NP_976031.1|dip:DIP-40302N|ensembl:ENSG00000110400(gene)|ensembl:ENST00000264025(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002934"(desmosome organization)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070166"(enamel mineralization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033314|interpro:IPR036179|interpro:IPR041849|interpro:IPR041850|rcsb pdb:3ALP|rcsb pdb:3SKU|rcsb pdb:3U82|rcsb pdb:3U83|rcsb pdb:4FMF|rcsb pdb:4MYW|reactome:R-HSA-418990|reactome:R-HSA-420597 go:"GO:0001618"(virus receptor activity)|mint:P15151|refseq:NP_001129240.1|refseq:NP_001129241.1|refseq:NP_006496.4|refseq:NP_001129242.2|dip:DIP-43987N|go:"GO:0002860"(positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042271"(susceptibility to natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060370"(susceptibility to T cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1DGI|rcsb pdb:1NN8|rcsb pdb:3EPC|rcsb pdb:3EPD|rcsb pdb:3EPF|rcsb pdb:3J8F|rcsb pdb:3J9F|rcsb pdb:3UDW|rcsb pdb:3URO|rcsb pdb:4FQP|rcsb pdb:6ARQ|rcsb pdb:6ISC|rcsb pdb:6O3O|reactome:R-HSA-198933|reactome:R-HSA-420597 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:/KqZN5Vhyc6Qrih7IyHnkN8nsaE9606 rogid:PsTFmeD+9vG6ieNef6MupXts60g9606 rigid:i+bAd8Fch6QuzbHUpp9L3Rsm+4E false sufficient binding region:31-337 sufficient binding region:21-334 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96NY8 uniprotkb:Q15223 intact:EBI-4314784|uniprotkb:Q96K15|uniprotkb:B4DQW3|ensembl:ENSP00000356991 intact:EBI-1771314|uniprotkb:O75465|uniprotkb:Q2M3D3|uniprotkb:Q9HBE6|uniprotkb:Q9HBW2|ensembl:ENSP00000264025 psi-mi:nect4_human(display_long)|uniprotkb:NECTIN4(gene name)|psi-mi:NECTIN4(display_short)|uniprotkb:Ig superfamily receptor LNIR(gene name synonym)|uniprotkb:LNIR(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 4(gene name synonym)|uniprotkb:PRR4(gene name synonym)|uniprotkb:PVRL4(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 4(gene name synonym) psi-mi:nect1_human(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Herpesvirus Ig-like receptor(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16008270|imex:IM-18564-26|dip:DIP-70528E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112178.2|ensembl:ENSG00000143217(gene)|ensembl:ENST00000368012(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033320|interpro:IPR036179|rcsb pdb:4FRW|rcsb pdb:4GJT|rcsb pdb:4JJH|reactome:R-HSA-418990|reactome:R-HSA-420597|dip:DIP-41492N refseq:NP_002846.3|refseq:NP_976030.1|refseq:NP_976031.1|dip:DIP-40302N|ensembl:ENSG00000110400(gene)|ensembl:ENST00000264025(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002934"(desmosome organization)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070166"(enamel mineralization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033314|interpro:IPR036179|interpro:IPR041849|interpro:IPR041850|rcsb pdb:3ALP|rcsb pdb:3SKU|rcsb pdb:3U82|rcsb pdb:3U83|rcsb pdb:4FMF|rcsb pdb:4MYW|reactome:R-HSA-418990|reactome:R-HSA-420597 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:xh33OK0Z4RsYD8uJZYbmnGfs/TQ9606 rogid:/KqZN5Vhyc6Qrih7IyHnkN8nsaE9606 rigid:hRMxaFNfMrQX1Np++7ViMPL0jdQ false sufficient binding region:32-336 sufficient binding region:31-337 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NQS3-1 uniprotkb:P15151 intact:EBI-16007706|ensembl:ENSP00000418070 intact:EBI-3919694|uniprotkb:Q96BJ1|uniprotkb:Q15268|uniprotkb:Q15267|uniprotkb:P15152|uniprotkb:B4DTS9 psi-mi:q9nqs3-1(display_long)|uniprotkb:NECTIN3(gene name)|psi-mi:NECTIN3(display_short)|uniprotkb:PRR3(gene name synonym)|uniprotkb:PVRL3(gene name synonym)|uniprotkb:CDw113(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 3(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 3(gene name synonym) psi-mi:pvr_human(display_long)|uniprotkb:PVR(gene name)|psi-mi:PVR(display_short)|uniprotkb:PVS(gene name synonym)|uniprotkb:Nectin-like protein 5(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Harrison et al. (2012) pubmed:22902367|doi:10.1038/nsmb.2366|imex:IM-18564 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16008291|imex:IM-18564-27|dip:DIP-190002E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2826725(isoform-parent)|ensembl:ENSG00000177707(gene)|ensembl:ENST00000485303(transcript) go:"GO:0001618"(virus receptor activity)|mint:P15151|refseq:NP_001129240.1|refseq:NP_001129241.1|refseq:NP_006496.4|refseq:NP_001129242.2|dip:DIP-43987N|go:"GO:0002860"(positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042271"(susceptibility to natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060370"(susceptibility to T cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1DGI|rcsb pdb:1NN8|rcsb pdb:3EPC|rcsb pdb:3EPD|rcsb pdb:3EPF|rcsb pdb:3J8F|rcsb pdb:3J9F|rcsb pdb:3UDW|rcsb pdb:3URO|rcsb pdb:4FQP|rcsb pdb:6ARQ|rcsb pdb:6ISC|rcsb pdb:6O3O|reactome:R-HSA-198933|reactome:R-HSA-420597 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:lzSScehKhxTPj0E6EmL+P+XXjB09606 rogid:PsTFmeD+9vG6ieNef6MupXts60g9606 rigid:FDgrwVaYaRWAVFpkjPJSlasOzCQ false sufficient binding region:58-359 sufficient binding region:21-334 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)