#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P12830	uniprotkb:P35221	intact:EBI-727477|uniprotkb:Q13799|uniprotkb:Q14216|uniprotkb:Q15855|uniprotkb:Q16194|uniprotkb:Q4PJ14|uniprotkb:A8K1U7|intact:EBI-28986920|ensembl:ENSP00000261769|uniprotkb:Q9UII8	intact:EBI-701918|uniprotkb:Q12795|intact:EBI-7950809|intact:MINT-4924748|uniprotkb:Q8N1C0|ensembl:ENSP00000304669	psi-mi:cadh1_human(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CAM 120/80(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:CDHE(gene name synonym)|uniprotkb:UVO(gene name synonym)	psi-mi:ctna1_human(display_long)|uniprotkb:Cadherin-associated protein(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-13(gene name synonym)|uniprotkb:CTNNA1(gene name)|psi-mi:CTNNA1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ratheesh et al. (2012)	pubmed:22750944|doi:10.1038/ncb2532|imex:IM-25171	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15993280|imex:IM-25171-1|dip:DIP-200618E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|ensembl:ENSG00000039068(gene)|refseq:NP_004351.1|ensembl:ENST00000261769(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|refseq:NP_001304113.1|refseq:NP_001304114.1|refseq:NP_001304115.1|ensembl:ENSP00000261769|ensembl:ENST00000422392|ensembl:ENSP00000414946|go:"GO:0016600"(flotillin complex)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|mint:P12830|rcsb pdb:1O6S|rcsb pdb:2O72|rcsb pdb:2OMT|rcsb pdb:2OMU|rcsb pdb:2OMV|rcsb pdb:2OMX|rcsb pdb:2OMY|rcsb pdb:2OMZ|rcsb pdb:3FF7|rcsb pdb:3FF8|rcsb pdb:3L6X|rcsb pdb:3L6Y|rcsb pdb:6VEL|reactome:R-HSA-1474228|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-351906|reactome:R-HSA-418990|reactome:R-HSA-5626467|reactome:R-HSA-8876493|rcsb pdb:4ZT1|rcsb pdb:4ZTE|rcsb pdb:6CXY|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|dip:DIP-477N	refseq:NP_001894.2|refseq:NP_001277236.1|refseq:NP_001277238.1|refseq:NP_001277239.1|refseq:NP_001277241.1|refseq:NP_001310911.1|refseq:NP_001310912.1|refseq:NP_001310913.1|refseq:NP_001310916.1|refseq:NP_001310917.1|refseq:NP_001310918.1|refseq:NP_001310919.1|refseq:NP_001310920.1|refseq:NP_001310921.1|refseq:NP_001310922.1|refseq:NP_001310923.1|refseq:NP_001310924.1|refseq:NP_001310925.1|refseq:NP_001310926.1|refseq:NP_001310927.1|refseq:NP_001310928.1|refseq:NP_001310929.1|dip:DIP-515N|ensembl:ENSG00000044115(gene)|ensembl:ENST00000302763(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P35221|rcsb pdb:1H6G|rcsb pdb:4EHP|rcsb pdb:4IGG|rcsb pdb:6UPV|rcsb pdb:6V2O|rcsb pdb:6V2P|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5626467	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:WI/yBLas6W5mlgbyOErqeeUFNA49606	rogid:N5rM8wI4ep+iZcnXU2g5wlJmJao9606	rigid:w6au3f9T3ODpjqK4MsqlseqD5zg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P12830	uniprotkb:Q9H8V3	intact:EBI-727477|uniprotkb:Q13799|uniprotkb:Q14216|uniprotkb:Q15855|uniprotkb:Q16194|uniprotkb:Q4PJ14|uniprotkb:A8K1U7|intact:EBI-28986920|ensembl:ENSP00000261769|uniprotkb:Q9UII8	intact:EBI-1054039|uniprotkb:Q9NSV8|uniprotkb:Q9NVW9|uniprotkb:Q0MT80|uniprotkb:Q6U836|uniprotkb:Q2M269|ensembl:ENSP00000376457	psi-mi:cadh1_human(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CAM 120/80(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:CDHE(gene name synonym)|uniprotkb:UVO(gene name synonym)	psi-mi:ect2_human(display_long)|uniprotkb:Epithelial cell-transforming sequence 2 oncogene(gene name synonym)|uniprotkb:ECT2(gene name)|psi-mi:ECT2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ratheesh et al. (2012)	pubmed:22750944|doi:10.1038/ncb2532|imex:IM-25171	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15993280|imex:IM-25171-1|dip:DIP-200618E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|ensembl:ENSG00000039068(gene)|refseq:NP_004351.1|ensembl:ENST00000261769(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|refseq:NP_001304113.1|refseq:NP_001304114.1|refseq:NP_001304115.1|ensembl:ENSP00000261769|ensembl:ENST00000422392|ensembl:ENSP00000414946|go:"GO:0016600"(flotillin complex)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|mint:P12830|rcsb pdb:1O6S|rcsb pdb:2O72|rcsb pdb:2OMT|rcsb pdb:2OMU|rcsb pdb:2OMV|rcsb pdb:2OMX|rcsb pdb:2OMY|rcsb pdb:2OMZ|rcsb pdb:3FF7|rcsb pdb:3FF8|rcsb pdb:3L6X|rcsb pdb:3L6Y|rcsb pdb:6VEL|reactome:R-HSA-1474228|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-351906|reactome:R-HSA-418990|reactome:R-HSA-5626467|reactome:R-HSA-8876493|rcsb pdb:4ZT1|rcsb pdb:4ZTE|rcsb pdb:6CXY|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|dip:DIP-477N	refseq:XP_011510816.1|refseq:NP_060568.3|refseq:NP_001245244.1|refseq:NP_001245245.1|ensembl:ENSG00000114346(gene)|ensembl:ENST00000392692(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007399"(nervous system development)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097149"(centralspindlin complex)|go:"GO:2000431"(regulation of cytokinesis, actomyosin contractile ring assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001357(BRCT)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036420|mint:Q9H8V3|rcsb pdb:3L46|rcsb pdb:4N40|rcsb pdb:6L30|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR026817|interpro:IPR035899|dip:DIP-47496N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:WI/yBLas6W5mlgbyOErqeeUFNA49606	rogid:ApqtJWU8n3b+PM8yUysFwFOkWuk9606	rigid:w6au3f9T3ODpjqK4MsqlseqD5zg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P12830	uniprotkb:Q9H8V3	intact:EBI-727477|uniprotkb:Q13799|uniprotkb:Q14216|uniprotkb:Q15855|uniprotkb:Q16194|uniprotkb:Q4PJ14|uniprotkb:A8K1U7|intact:EBI-28986920|ensembl:ENSP00000261769|uniprotkb:Q9UII8	intact:EBI-1054039|uniprotkb:Q9NSV8|uniprotkb:Q9NVW9|uniprotkb:Q0MT80|uniprotkb:Q6U836|uniprotkb:Q2M269|ensembl:ENSP00000376457	psi-mi:cadh1_human(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CAM 120/80(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:CDHE(gene name synonym)|uniprotkb:UVO(gene name synonym)	psi-mi:ect2_human(display_long)|uniprotkb:Epithelial cell-transforming sequence 2 oncogene(gene name synonym)|uniprotkb:ECT2(gene name)|psi-mi:ECT2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ratheesh et al. (2012)	pubmed:22750944|doi:10.1038/ncb2532|imex:IM-25171	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15993316|imex:IM-25171-3|dip:DIP-200619E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|ensembl:ENSG00000039068(gene)|refseq:NP_004351.1|ensembl:ENST00000261769(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|refseq:NP_001304113.1|refseq:NP_001304114.1|refseq:NP_001304115.1|ensembl:ENSP00000261769|ensembl:ENST00000422392|ensembl:ENSP00000414946|go:"GO:0016600"(flotillin complex)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|mint:P12830|rcsb pdb:1O6S|rcsb pdb:2O72|rcsb pdb:2OMT|rcsb pdb:2OMU|rcsb pdb:2OMV|rcsb pdb:2OMX|rcsb pdb:2OMY|rcsb pdb:2OMZ|rcsb pdb:3FF7|rcsb pdb:3FF8|rcsb pdb:3L6X|rcsb pdb:3L6Y|rcsb pdb:6VEL|reactome:R-HSA-1474228|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-351906|reactome:R-HSA-418990|reactome:R-HSA-5626467|reactome:R-HSA-8876493|rcsb pdb:4ZT1|rcsb pdb:4ZTE|rcsb pdb:6CXY|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|dip:DIP-477N	refseq:XP_011510816.1|refseq:NP_060568.3|refseq:NP_001245244.1|refseq:NP_001245245.1|ensembl:ENSG00000114346(gene)|ensembl:ENST00000392692(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007399"(nervous system development)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097149"(centralspindlin complex)|go:"GO:2000431"(regulation of cytokinesis, actomyosin contractile ring assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001357(BRCT)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036420|mint:Q9H8V3|rcsb pdb:3L46|rcsb pdb:4N40|rcsb pdb:6L30|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR026817|interpro:IPR035899|dip:DIP-47496N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:WI/yBLas6W5mlgbyOErqeeUFNA49606	rogid:ApqtJWU8n3b+PM8yUysFwFOkWuk9606	rigid:47Uv0yVespLbK4n0if8OmiitFQw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H8V3	uniprotkb:Q02241	intact:EBI-1054039|uniprotkb:Q9NSV8|uniprotkb:Q9NVW9|uniprotkb:Q0MT80|uniprotkb:Q6U836|uniprotkb:Q2M269|ensembl:ENSP00000376457	intact:EBI-306852|uniprotkb:Q8WVP0|ensembl:ENSP00000260363|ensembl:ENSP00000497065|intact:EBI-2558308|uniprotkb:B4E1K0	psi-mi:ect2_human(display_long)|uniprotkb:Epithelial cell-transforming sequence 2 oncogene(gene name synonym)|uniprotkb:ECT2(gene name)|psi-mi:ECT2(display_short)	psi-mi:kif23_human(display_long)|uniprotkb:KIF23(gene name)|psi-mi:KIF23(display_short)|uniprotkb:KNSL5(gene name synonym)|uniprotkb:MKLP1(gene name synonym)|uniprotkb:Mitotic kinesin-like protein 1(gene name synonym)|uniprotkb:Kinesin-like protein 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ratheesh et al. (2012)	pubmed:22750944|doi:10.1038/ncb2532|imex:IM-25171	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15993298|imex:IM-25171-2|dip:DIP-200617E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011510816.1|refseq:NP_060568.3|refseq:NP_001245244.1|refseq:NP_001245245.1|ensembl:ENSG00000114346(gene)|ensembl:ENST00000392692(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007399"(nervous system development)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097149"(centralspindlin complex)|go:"GO:2000431"(regulation of cytokinesis, actomyosin contractile ring assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001357(BRCT)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036420|mint:Q9H8V3|rcsb pdb:3L46|rcsb pdb:4N40|rcsb pdb:6L30|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR026817|interpro:IPR035899|dip:DIP-47496N	refseq:NP_004847.2|refseq:NP_612565.1|ensembl:ENSG00000137807(gene)|ensembl:ENST00000260363(transcript)|ensembl:ENST00000647715(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|go:"GO:0000281"(mitotic cytokinesis)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR038105|mint:Q02241|rcsb pdb:3VHX|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-68884|interpro:IPR032384|reactome:R-HSA-983189|ensembl:ENSP00000260363|ensembl:ENST00000352331|ensembl:ENSP00000304978|ensembl:ENSP00000497065|dip:DIP-40359N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:ApqtJWU8n3b+PM8yUysFwFOkWuk9606	rogid:akVjKfOv4g4nEsGN8E3lQ2vCseQ9606	rigid:xr8ay7GBCAq7YEbobubCjS2BCcE	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9H8V3	uniprotkb:Q9H0H5	intact:EBI-1054039|uniprotkb:Q9NSV8|uniprotkb:Q9NVW9|uniprotkb:Q0MT80|uniprotkb:Q6U836|uniprotkb:Q2M269|ensembl:ENSP00000376457	intact:EBI-717233|uniprotkb:Q6PJ26|uniprotkb:Q9NWN2|uniprotkb:Q9P250|uniprotkb:Q9P2W2|ensembl:ENSP00000309871|ensembl:ENSP00000404190|ensembl:ENSP00000404808|ensembl:ENSP00000449370|ensembl:ENSP00000449374	psi-mi:ect2_human(display_long)|uniprotkb:Epithelial cell-transforming sequence 2 oncogene(gene name synonym)|uniprotkb:ECT2(gene name)|psi-mi:ECT2(display_short)	psi-mi:rgap1_human(display_long)|uniprotkb:Male germ cell RacGap(gene name synonym)|uniprotkb:RACGAP1(gene name)|psi-mi:RACGAP1(display_short)|uniprotkb:KIAA1478(gene name synonym)|uniprotkb:MGCRACGAP(gene name synonym)|uniprotkb:Protein CYK4 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ratheesh et al. (2012)	pubmed:22750944|doi:10.1038/ncb2532|imex:IM-25171	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15993298|imex:IM-25171-2|dip:DIP-200617E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011510816.1|refseq:NP_060568.3|refseq:NP_001245244.1|refseq:NP_001245245.1|ensembl:ENSG00000114346(gene)|ensembl:ENST00000392692(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007399"(nervous system development)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097149"(centralspindlin complex)|go:"GO:2000431"(regulation of cytokinesis, actomyosin contractile ring assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001357(BRCT)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036420|mint:Q9H8V3|rcsb pdb:3L46|rcsb pdb:4N40|rcsb pdb:6L30|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR026817|interpro:IPR035899|dip:DIP-47496N	refseq:NP_001119575.1|refseq:NP_001119576.1|refseq:NP_037409.2|refseq:NP_001306928.1|refseq:NP_001306929.1|refseq:NP_001306930.1|refseq:NP_001306931.1|refseq:NP_001306932.1|refseq:NP_001306933.1|refseq:NP_001306934.1|refseq:NP_001306935.1|refseq:NP_001306936.1|refseq:XP_011536540.1|refseq:XP_006719422.1|refseq:XP_016874709.1|ensembl:ENSG00000161800(gene)|ensembl:ENST00000312377(transcript)|ensembl:ENST00000427314(transcript)|ensembl:ENST00000454520(transcript)|ensembl:ENST00000547905(transcript)|ensembl:ENST00000551016(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008272"(sulfate transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q9H0H5|rcsb pdb:2OVJ|rcsb pdb:3W6R|rcsb pdb:3WPQ|rcsb pdb:3WPS|rcsb pdb:4B6D|rcsb pdb:5C2J|rcsb pdb:5C2K|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013423|reactome:R-HSA-983189|dip:DIP-33087N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:ApqtJWU8n3b+PM8yUysFwFOkWuk9606	rogid:cjlAuqAG2p8cju3iMfySUeETiAU9606	rigid:xr8ay7GBCAq7YEbobubCjS2BCcE	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9H0H5	uniprotkb:P12830	intact:EBI-717233|uniprotkb:Q6PJ26|uniprotkb:Q9NWN2|uniprotkb:Q9P250|uniprotkb:Q9P2W2|ensembl:ENSP00000309871|ensembl:ENSP00000404190|ensembl:ENSP00000404808|ensembl:ENSP00000449370|ensembl:ENSP00000449374	intact:EBI-727477|uniprotkb:Q13799|uniprotkb:Q14216|uniprotkb:Q15855|uniprotkb:Q16194|uniprotkb:Q4PJ14|uniprotkb:A8K1U7|intact:EBI-28986920|ensembl:ENSP00000261769|uniprotkb:Q9UII8	psi-mi:rgap1_human(display_long)|uniprotkb:Male germ cell RacGap(gene name synonym)|uniprotkb:RACGAP1(gene name)|psi-mi:RACGAP1(display_short)|uniprotkb:KIAA1478(gene name synonym)|uniprotkb:MGCRACGAP(gene name synonym)|uniprotkb:Protein CYK4 homolog(gene name synonym)	psi-mi:cadh1_human(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CAM 120/80(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:CDHE(gene name synonym)|uniprotkb:UVO(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ratheesh et al. (2012)	pubmed:22750944|doi:10.1038/ncb2532|imex:IM-25171	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15993333|imex:IM-25171-4|dip:DIP-200620E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001119575.1|refseq:NP_001119576.1|refseq:NP_037409.2|refseq:NP_001306928.1|refseq:NP_001306929.1|refseq:NP_001306930.1|refseq:NP_001306931.1|refseq:NP_001306932.1|refseq:NP_001306933.1|refseq:NP_001306934.1|refseq:NP_001306935.1|refseq:NP_001306936.1|refseq:XP_011536540.1|refseq:XP_006719422.1|refseq:XP_016874709.1|ensembl:ENSG00000161800(gene)|ensembl:ENST00000312377(transcript)|ensembl:ENST00000427314(transcript)|ensembl:ENST00000454520(transcript)|ensembl:ENST00000547905(transcript)|ensembl:ENST00000551016(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008272"(sulfate transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q9H0H5|rcsb pdb:2OVJ|rcsb pdb:3W6R|rcsb pdb:3WPQ|rcsb pdb:3WPS|rcsb pdb:4B6D|rcsb pdb:5C2J|rcsb pdb:5C2K|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013423|reactome:R-HSA-983189|dip:DIP-33087N	go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|ensembl:ENSG00000039068(gene)|refseq:NP_004351.1|ensembl:ENST00000261769(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|refseq:NP_001304113.1|refseq:NP_001304114.1|refseq:NP_001304115.1|ensembl:ENSP00000261769|ensembl:ENST00000422392|ensembl:ENSP00000414946|go:"GO:0016600"(flotillin complex)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|mint:P12830|rcsb pdb:1O6S|rcsb pdb:2O72|rcsb pdb:2OMT|rcsb pdb:2OMU|rcsb pdb:2OMV|rcsb pdb:2OMX|rcsb pdb:2OMY|rcsb pdb:2OMZ|rcsb pdb:3FF7|rcsb pdb:3FF8|rcsb pdb:3L6X|rcsb pdb:3L6Y|rcsb pdb:6VEL|reactome:R-HSA-1474228|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-351906|reactome:R-HSA-418990|reactome:R-HSA-5626467|reactome:R-HSA-8876493|rcsb pdb:4ZT1|rcsb pdb:4ZTE|rcsb pdb:6CXY|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|dip:DIP-477N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:cjlAuqAG2p8cju3iMfySUeETiAU9606	rogid:WI/yBLas6W5mlgbyOErqeeUFNA49606	rigid:jZEUWS1BM8Yz53X2O/AeSAAcaWY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H0H5	uniprotkb:P35221	intact:EBI-717233|uniprotkb:Q6PJ26|uniprotkb:Q9NWN2|uniprotkb:Q9P250|uniprotkb:Q9P2W2|ensembl:ENSP00000309871|ensembl:ENSP00000404190|ensembl:ENSP00000404808|ensembl:ENSP00000449370|ensembl:ENSP00000449374	intact:EBI-701918|uniprotkb:Q12795|intact:EBI-7950809|intact:MINT-4924748|uniprotkb:Q8N1C0|ensembl:ENSP00000304669	psi-mi:rgap1_human(display_long)|uniprotkb:Male germ cell RacGap(gene name synonym)|uniprotkb:RACGAP1(gene name)|psi-mi:RACGAP1(display_short)|uniprotkb:KIAA1478(gene name synonym)|uniprotkb:MGCRACGAP(gene name synonym)|uniprotkb:Protein CYK4 homolog(gene name synonym)	psi-mi:ctna1_human(display_long)|uniprotkb:Cadherin-associated protein(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-13(gene name synonym)|uniprotkb:CTNNA1(gene name)|psi-mi:CTNNA1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ratheesh et al. (2012)	pubmed:22750944|doi:10.1038/ncb2532|imex:IM-25171	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15993333|imex:IM-25171-4|dip:DIP-200620E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001119575.1|refseq:NP_001119576.1|refseq:NP_037409.2|refseq:NP_001306928.1|refseq:NP_001306929.1|refseq:NP_001306930.1|refseq:NP_001306931.1|refseq:NP_001306932.1|refseq:NP_001306933.1|refseq:NP_001306934.1|refseq:NP_001306935.1|refseq:NP_001306936.1|refseq:XP_011536540.1|refseq:XP_006719422.1|refseq:XP_016874709.1|ensembl:ENSG00000161800(gene)|ensembl:ENST00000312377(transcript)|ensembl:ENST00000427314(transcript)|ensembl:ENST00000454520(transcript)|ensembl:ENST00000547905(transcript)|ensembl:ENST00000551016(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008272"(sulfate transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q9H0H5|rcsb pdb:2OVJ|rcsb pdb:3W6R|rcsb pdb:3WPQ|rcsb pdb:3WPS|rcsb pdb:4B6D|rcsb pdb:5C2J|rcsb pdb:5C2K|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013423|reactome:R-HSA-983189|dip:DIP-33087N	refseq:NP_001894.2|refseq:NP_001277236.1|refseq:NP_001277238.1|refseq:NP_001277239.1|refseq:NP_001277241.1|refseq:NP_001310911.1|refseq:NP_001310912.1|refseq:NP_001310913.1|refseq:NP_001310916.1|refseq:NP_001310917.1|refseq:NP_001310918.1|refseq:NP_001310919.1|refseq:NP_001310920.1|refseq:NP_001310921.1|refseq:NP_001310922.1|refseq:NP_001310923.1|refseq:NP_001310924.1|refseq:NP_001310925.1|refseq:NP_001310926.1|refseq:NP_001310927.1|refseq:NP_001310928.1|refseq:NP_001310929.1|dip:DIP-515N|ensembl:ENSG00000044115(gene)|ensembl:ENST00000302763(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P35221|rcsb pdb:1H6G|rcsb pdb:4EHP|rcsb pdb:4IGG|rcsb pdb:6UPV|rcsb pdb:6V2O|rcsb pdb:6V2P|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5626467	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:cjlAuqAG2p8cju3iMfySUeETiAU9606	rogid:N5rM8wI4ep+iZcnXU2g5wlJmJao9606	rigid:jZEUWS1BM8Yz53X2O/AeSAAcaWY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P26231	uniprotkb:Q9H8V3	intact:EBI-647895|ensembl:ENSMUSP00000049007	intact:EBI-1054039|uniprotkb:Q9NSV8|uniprotkb:Q9NVW9|uniprotkb:Q0MT80|uniprotkb:Q6U836|uniprotkb:Q2M269|ensembl:ENSP00000376457	psi-mi:ctna1_mouse(display_long)|uniprotkb:102 kDa cadherin-associated protein(gene name synonym)|uniprotkb:CAP102(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Ctnna1(gene name)|psi-mi:Ctnna1(display_short)|uniprotkb:Catna1(gene name synonym)	psi-mi:ect2_human(display_long)|uniprotkb:Epithelial cell-transforming sequence 2 oncogene(gene name synonym)|uniprotkb:ECT2(gene name)|psi-mi:ECT2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ratheesh et al. (2012)	pubmed:22750944|doi:10.1038/ncb2532|imex:IM-25171	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15993351|imex:IM-25171-5|dip:DIP-200623E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033948.1|refseq:XP_011245120.1|dip:DIP-35299N|ensembl:ENSMUSG00000037815(gene)|ensembl:ENSMUST00000042345(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P26231|rcsb pdb:1DOV|rcsb pdb:1DOW|rcsb pdb:1L7C|rcsb pdb:4E17|rcsb pdb:4E18|rcsb pdb:4K1N|rcsb pdb:5Y04|rcsb pdb:6DV1|rcsb pdb:6O3E|rcsb pdb:6WVT|reactome:R-MMU-418990|reactome:R-MMU-5218920|reactome:R-MMU-525793|reactome:R-MMU-5626467	refseq:XP_011510816.1|refseq:NP_060568.3|refseq:NP_001245244.1|refseq:NP_001245245.1|ensembl:ENSG00000114346(gene)|ensembl:ENST00000392692(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007399"(nervous system development)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097149"(centralspindlin complex)|go:"GO:2000431"(regulation of cytokinesis, actomyosin contractile ring assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001357(BRCT)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036420|mint:Q9H8V3|rcsb pdb:3L46|rcsb pdb:4N40|rcsb pdb:6L30|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR026817|interpro:IPR035899|dip:DIP-47496N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:2GScCoVKWPHfjBJE6Gm6yVmO/IA10090	rogid:ApqtJWU8n3b+PM8yUysFwFOkWuk9606	rigid:o0ttDccbA09JFiLLSpjUzjrI+Ng	false	sufficient binding region:1-290|green fluorescent protein tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P26231	uniprotkb:Q9H0H5	intact:EBI-647895|ensembl:ENSMUSP00000049007	intact:EBI-717233|uniprotkb:Q6PJ26|uniprotkb:Q9NWN2|uniprotkb:Q9P250|uniprotkb:Q9P2W2|ensembl:ENSP00000309871|ensembl:ENSP00000404190|ensembl:ENSP00000404808|ensembl:ENSP00000449370|ensembl:ENSP00000449374	psi-mi:ctna1_mouse(display_long)|uniprotkb:102 kDa cadherin-associated protein(gene name synonym)|uniprotkb:CAP102(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Ctnna1(gene name)|psi-mi:Ctnna1(display_short)|uniprotkb:Catna1(gene name synonym)	psi-mi:rgap1_human(display_long)|uniprotkb:Male germ cell RacGap(gene name synonym)|uniprotkb:RACGAP1(gene name)|psi-mi:RACGAP1(display_short)|uniprotkb:KIAA1478(gene name synonym)|uniprotkb:MGCRACGAP(gene name synonym)|uniprotkb:Protein CYK4 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ratheesh et al. (2012)	pubmed:22750944|doi:10.1038/ncb2532|imex:IM-25171	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15993351|imex:IM-25171-5|dip:DIP-200623E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033948.1|refseq:XP_011245120.1|dip:DIP-35299N|ensembl:ENSMUSG00000037815(gene)|ensembl:ENSMUST00000042345(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P26231|rcsb pdb:1DOV|rcsb pdb:1DOW|rcsb pdb:1L7C|rcsb pdb:4E17|rcsb pdb:4E18|rcsb pdb:4K1N|rcsb pdb:5Y04|rcsb pdb:6DV1|rcsb pdb:6O3E|rcsb pdb:6WVT|reactome:R-MMU-418990|reactome:R-MMU-5218920|reactome:R-MMU-525793|reactome:R-MMU-5626467	refseq:NP_001119575.1|refseq:NP_001119576.1|refseq:NP_037409.2|refseq:NP_001306928.1|refseq:NP_001306929.1|refseq:NP_001306930.1|refseq:NP_001306931.1|refseq:NP_001306932.1|refseq:NP_001306933.1|refseq:NP_001306934.1|refseq:NP_001306935.1|refseq:NP_001306936.1|refseq:XP_011536540.1|refseq:XP_006719422.1|refseq:XP_016874709.1|ensembl:ENSG00000161800(gene)|ensembl:ENST00000312377(transcript)|ensembl:ENST00000427314(transcript)|ensembl:ENST00000454520(transcript)|ensembl:ENST00000547905(transcript)|ensembl:ENST00000551016(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008272"(sulfate transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q9H0H5|rcsb pdb:2OVJ|rcsb pdb:3W6R|rcsb pdb:3WPQ|rcsb pdb:3WPS|rcsb pdb:4B6D|rcsb pdb:5C2J|rcsb pdb:5C2K|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013423|reactome:R-HSA-983189|dip:DIP-33087N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:2GScCoVKWPHfjBJE6Gm6yVmO/IA10090	rogid:cjlAuqAG2p8cju3iMfySUeETiAU9606	rigid:o0ttDccbA09JFiLLSpjUzjrI+Ng	false	sufficient binding region:1-290|green fluorescent protein tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P35221	uniprotkb:P12830	intact:EBI-701918|uniprotkb:Q12795|intact:EBI-7950809|intact:MINT-4924748|uniprotkb:Q8N1C0|ensembl:ENSP00000304669	intact:EBI-727477|uniprotkb:Q13799|uniprotkb:Q14216|uniprotkb:Q15855|uniprotkb:Q16194|uniprotkb:Q4PJ14|uniprotkb:A8K1U7|intact:EBI-28986920|ensembl:ENSP00000261769|uniprotkb:Q9UII8	psi-mi:ctna1_human(display_long)|uniprotkb:Cadherin-associated protein(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-13(gene name synonym)|uniprotkb:CTNNA1(gene name)|psi-mi:CTNNA1(display_short)	psi-mi:cadh1_human(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CAM 120/80(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:CDHE(gene name synonym)|uniprotkb:UVO(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ratheesh et al. (2012)	pubmed:22750944|doi:10.1038/ncb2532|imex:IM-25171	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15993373|imex:IM-25171-6|dip:DIP-85929E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001894.2|refseq:NP_001277236.1|refseq:NP_001277238.1|refseq:NP_001277239.1|refseq:NP_001277241.1|refseq:NP_001310911.1|refseq:NP_001310912.1|refseq:NP_001310913.1|refseq:NP_001310916.1|refseq:NP_001310917.1|refseq:NP_001310918.1|refseq:NP_001310919.1|refseq:NP_001310920.1|refseq:NP_001310921.1|refseq:NP_001310922.1|refseq:NP_001310923.1|refseq:NP_001310924.1|refseq:NP_001310925.1|refseq:NP_001310926.1|refseq:NP_001310927.1|refseq:NP_001310928.1|refseq:NP_001310929.1|dip:DIP-515N|ensembl:ENSG00000044115(gene)|ensembl:ENST00000302763(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P35221|rcsb pdb:1H6G|rcsb pdb:4EHP|rcsb pdb:4IGG|rcsb pdb:6UPV|rcsb pdb:6V2O|rcsb pdb:6V2P|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5626467	go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|ensembl:ENSG00000039068(gene)|refseq:NP_004351.1|ensembl:ENST00000261769(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|refseq:NP_001304113.1|refseq:NP_001304114.1|refseq:NP_001304115.1|ensembl:ENSP00000261769|ensembl:ENST00000422392|ensembl:ENSP00000414946|go:"GO:0016600"(flotillin complex)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|mint:P12830|rcsb pdb:1O6S|rcsb pdb:2O72|rcsb pdb:2OMT|rcsb pdb:2OMU|rcsb pdb:2OMV|rcsb pdb:2OMX|rcsb pdb:2OMY|rcsb pdb:2OMZ|rcsb pdb:3FF7|rcsb pdb:3FF8|rcsb pdb:3L6X|rcsb pdb:3L6Y|rcsb pdb:6VEL|reactome:R-HSA-1474228|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-351906|reactome:R-HSA-418990|reactome:R-HSA-5626467|reactome:R-HSA-8876493|rcsb pdb:4ZT1|rcsb pdb:4ZTE|rcsb pdb:6CXY|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|dip:DIP-477N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:N5rM8wI4ep+iZcnXU2g5wlJmJao9606	rogid:WI/yBLas6W5mlgbyOErqeeUFNA49606	rigid:z3dMgFJdL6B5fB9wtHa6Ts0xfsw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H8V3	uniprotkb:P35221	intact:EBI-1054039|uniprotkb:Q9NSV8|uniprotkb:Q9NVW9|uniprotkb:Q0MT80|uniprotkb:Q6U836|uniprotkb:Q2M269|ensembl:ENSP00000376457	intact:EBI-701918|uniprotkb:Q12795|intact:EBI-7950809|intact:MINT-4924748|uniprotkb:Q8N1C0|ensembl:ENSP00000304669	psi-mi:ect2_human(display_long)|uniprotkb:Epithelial cell-transforming sequence 2 oncogene(gene name synonym)|uniprotkb:ECT2(gene name)|psi-mi:ECT2(display_short)	psi-mi:ctna1_human(display_long)|uniprotkb:Cadherin-associated protein(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-13(gene name synonym)|uniprotkb:CTNNA1(gene name)|psi-mi:CTNNA1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ratheesh et al. (2012)	pubmed:22750944|doi:10.1038/ncb2532|imex:IM-25171	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15993425|imex:IM-25171-9|dip:DIP-200618E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011510816.1|refseq:NP_060568.3|refseq:NP_001245244.1|refseq:NP_001245245.1|ensembl:ENSG00000114346(gene)|ensembl:ENST00000392692(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007399"(nervous system development)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097149"(centralspindlin complex)|go:"GO:2000431"(regulation of cytokinesis, actomyosin contractile ring assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001357(BRCT)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036420|mint:Q9H8V3|rcsb pdb:3L46|rcsb pdb:4N40|rcsb pdb:6L30|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR026817|interpro:IPR035899|dip:DIP-47496N	refseq:NP_001894.2|refseq:NP_001277236.1|refseq:NP_001277238.1|refseq:NP_001277239.1|refseq:NP_001277241.1|refseq:NP_001310911.1|refseq:NP_001310912.1|refseq:NP_001310913.1|refseq:NP_001310916.1|refseq:NP_001310917.1|refseq:NP_001310918.1|refseq:NP_001310919.1|refseq:NP_001310920.1|refseq:NP_001310921.1|refseq:NP_001310922.1|refseq:NP_001310923.1|refseq:NP_001310924.1|refseq:NP_001310925.1|refseq:NP_001310926.1|refseq:NP_001310927.1|refseq:NP_001310928.1|refseq:NP_001310929.1|dip:DIP-515N|ensembl:ENSG00000044115(gene)|ensembl:ENST00000302763(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P35221|rcsb pdb:1H6G|rcsb pdb:4EHP|rcsb pdb:4IGG|rcsb pdb:6UPV|rcsb pdb:6V2O|rcsb pdb:6V2P|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5626467	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:ApqtJWU8n3b+PM8yUysFwFOkWuk9606	rogid:N5rM8wI4ep+iZcnXU2g5wlJmJao9606	rigid:w6au3f9T3ODpjqK4MsqlseqD5zg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H8V3	uniprotkb:P12830	intact:EBI-1054039|uniprotkb:Q9NSV8|uniprotkb:Q9NVW9|uniprotkb:Q0MT80|uniprotkb:Q6U836|uniprotkb:Q2M269|ensembl:ENSP00000376457	intact:EBI-727477|uniprotkb:Q13799|uniprotkb:Q14216|uniprotkb:Q15855|uniprotkb:Q16194|uniprotkb:Q4PJ14|uniprotkb:A8K1U7|intact:EBI-28986920|ensembl:ENSP00000261769|uniprotkb:Q9UII8	psi-mi:ect2_human(display_long)|uniprotkb:Epithelial cell-transforming sequence 2 oncogene(gene name synonym)|uniprotkb:ECT2(gene name)|psi-mi:ECT2(display_short)	psi-mi:cadh1_human(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CAM 120/80(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:CDHE(gene name synonym)|uniprotkb:UVO(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ratheesh et al. (2012)	pubmed:22750944|doi:10.1038/ncb2532|imex:IM-25171	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15993425|imex:IM-25171-9|dip:DIP-200618E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011510816.1|refseq:NP_060568.3|refseq:NP_001245244.1|refseq:NP_001245245.1|ensembl:ENSG00000114346(gene)|ensembl:ENST00000392692(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007399"(nervous system development)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097149"(centralspindlin complex)|go:"GO:2000431"(regulation of cytokinesis, actomyosin contractile ring assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001357(BRCT)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036420|mint:Q9H8V3|rcsb pdb:3L46|rcsb pdb:4N40|rcsb pdb:6L30|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR026817|interpro:IPR035899|dip:DIP-47496N	go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|ensembl:ENSG00000039068(gene)|refseq:NP_004351.1|ensembl:ENST00000261769(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|refseq:NP_001304113.1|refseq:NP_001304114.1|refseq:NP_001304115.1|ensembl:ENSP00000261769|ensembl:ENST00000422392|ensembl:ENSP00000414946|go:"GO:0016600"(flotillin complex)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|mint:P12830|rcsb pdb:1O6S|rcsb pdb:2O72|rcsb pdb:2OMT|rcsb pdb:2OMU|rcsb pdb:2OMV|rcsb pdb:2OMX|rcsb pdb:2OMY|rcsb pdb:2OMZ|rcsb pdb:3FF7|rcsb pdb:3FF8|rcsb pdb:3L6X|rcsb pdb:3L6Y|rcsb pdb:6VEL|reactome:R-HSA-1474228|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-351906|reactome:R-HSA-418990|reactome:R-HSA-5626467|reactome:R-HSA-8876493|rcsb pdb:4ZT1|rcsb pdb:4ZTE|rcsb pdb:6CXY|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|dip:DIP-477N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:ApqtJWU8n3b+PM8yUysFwFOkWuk9606	rogid:WI/yBLas6W5mlgbyOErqeeUFNA49606	rigid:w6au3f9T3ODpjqK4MsqlseqD5zg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H0H5	uniprotkb:P35221	intact:EBI-717233|uniprotkb:Q6PJ26|uniprotkb:Q9NWN2|uniprotkb:Q9P250|uniprotkb:Q9P2W2|ensembl:ENSP00000309871|ensembl:ENSP00000404190|ensembl:ENSP00000404808|ensembl:ENSP00000449370|ensembl:ENSP00000449374	intact:EBI-701918|uniprotkb:Q12795|intact:EBI-7950809|intact:MINT-4924748|uniprotkb:Q8N1C0|ensembl:ENSP00000304669	psi-mi:rgap1_human(display_long)|uniprotkb:Male germ cell RacGap(gene name synonym)|uniprotkb:RACGAP1(gene name)|psi-mi:RACGAP1(display_short)|uniprotkb:KIAA1478(gene name synonym)|uniprotkb:MGCRACGAP(gene name synonym)|uniprotkb:Protein CYK4 homolog(gene name synonym)	psi-mi:ctna1_human(display_long)|uniprotkb:Cadherin-associated protein(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-13(gene name synonym)|uniprotkb:CTNNA1(gene name)|psi-mi:CTNNA1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ratheesh et al. (2012)	pubmed:22750944|doi:10.1038/ncb2532|imex:IM-25171	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15993408|imex:IM-25171-8|dip:DIP-200622E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001119575.1|refseq:NP_001119576.1|refseq:NP_037409.2|refseq:NP_001306928.1|refseq:NP_001306929.1|refseq:NP_001306930.1|refseq:NP_001306931.1|refseq:NP_001306932.1|refseq:NP_001306933.1|refseq:NP_001306934.1|refseq:NP_001306935.1|refseq:NP_001306936.1|refseq:XP_011536540.1|refseq:XP_006719422.1|refseq:XP_016874709.1|ensembl:ENSG00000161800(gene)|ensembl:ENST00000312377(transcript)|ensembl:ENST00000427314(transcript)|ensembl:ENST00000454520(transcript)|ensembl:ENST00000547905(transcript)|ensembl:ENST00000551016(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008272"(sulfate transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q9H0H5|rcsb pdb:2OVJ|rcsb pdb:3W6R|rcsb pdb:3WPQ|rcsb pdb:3WPS|rcsb pdb:4B6D|rcsb pdb:5C2J|rcsb pdb:5C2K|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013423|reactome:R-HSA-983189|dip:DIP-33087N	refseq:NP_001894.2|refseq:NP_001277236.1|refseq:NP_001277238.1|refseq:NP_001277239.1|refseq:NP_001277241.1|refseq:NP_001310911.1|refseq:NP_001310912.1|refseq:NP_001310913.1|refseq:NP_001310916.1|refseq:NP_001310917.1|refseq:NP_001310918.1|refseq:NP_001310919.1|refseq:NP_001310920.1|refseq:NP_001310921.1|refseq:NP_001310922.1|refseq:NP_001310923.1|refseq:NP_001310924.1|refseq:NP_001310925.1|refseq:NP_001310926.1|refseq:NP_001310927.1|refseq:NP_001310928.1|refseq:NP_001310929.1|dip:DIP-515N|ensembl:ENSG00000044115(gene)|ensembl:ENST00000302763(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P35221|rcsb pdb:1H6G|rcsb pdb:4EHP|rcsb pdb:4IGG|rcsb pdb:6UPV|rcsb pdb:6V2O|rcsb pdb:6V2P|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5626467	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:cjlAuqAG2p8cju3iMfySUeETiAU9606	rogid:N5rM8wI4ep+iZcnXU2g5wlJmJao9606	rigid:qK3WnAOcgTNWMAmtMvtd1dKNf1g	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P35221	uniprotkb:P12830	intact:EBI-701918|uniprotkb:Q12795|intact:EBI-7950809|intact:MINT-4924748|uniprotkb:Q8N1C0|ensembl:ENSP00000304669	intact:EBI-727477|uniprotkb:Q13799|uniprotkb:Q14216|uniprotkb:Q15855|uniprotkb:Q16194|uniprotkb:Q4PJ14|uniprotkb:A8K1U7|intact:EBI-28986920|ensembl:ENSP00000261769|uniprotkb:Q9UII8	psi-mi:ctna1_human(display_long)|uniprotkb:Cadherin-associated protein(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-13(gene name synonym)|uniprotkb:CTNNA1(gene name)|psi-mi:CTNNA1(display_short)	psi-mi:cadh1_human(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CAM 120/80(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:CDHE(gene name synonym)|uniprotkb:UVO(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ratheesh et al. (2012)	pubmed:22750944|doi:10.1038/ncb2532|imex:IM-25171	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15993390|imex:IM-25171-7|dip:DIP-200618E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001894.2|refseq:NP_001277236.1|refseq:NP_001277238.1|refseq:NP_001277239.1|refseq:NP_001277241.1|refseq:NP_001310911.1|refseq:NP_001310912.1|refseq:NP_001310913.1|refseq:NP_001310916.1|refseq:NP_001310917.1|refseq:NP_001310918.1|refseq:NP_001310919.1|refseq:NP_001310920.1|refseq:NP_001310921.1|refseq:NP_001310922.1|refseq:NP_001310923.1|refseq:NP_001310924.1|refseq:NP_001310925.1|refseq:NP_001310926.1|refseq:NP_001310927.1|refseq:NP_001310928.1|refseq:NP_001310929.1|dip:DIP-515N|ensembl:ENSG00000044115(gene)|ensembl:ENST00000302763(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P35221|rcsb pdb:1H6G|rcsb pdb:4EHP|rcsb pdb:4IGG|rcsb pdb:6UPV|rcsb pdb:6V2O|rcsb pdb:6V2P|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5626467	go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|ensembl:ENSG00000039068(gene)|refseq:NP_004351.1|ensembl:ENST00000261769(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|refseq:NP_001304113.1|refseq:NP_001304114.1|refseq:NP_001304115.1|ensembl:ENSP00000261769|ensembl:ENST00000422392|ensembl:ENSP00000414946|go:"GO:0016600"(flotillin complex)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|mint:P12830|rcsb pdb:1O6S|rcsb pdb:2O72|rcsb pdb:2OMT|rcsb pdb:2OMU|rcsb pdb:2OMV|rcsb pdb:2OMX|rcsb pdb:2OMY|rcsb pdb:2OMZ|rcsb pdb:3FF7|rcsb pdb:3FF8|rcsb pdb:3L6X|rcsb pdb:3L6Y|rcsb pdb:6VEL|reactome:R-HSA-1474228|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-351906|reactome:R-HSA-418990|reactome:R-HSA-5626467|reactome:R-HSA-8876493|rcsb pdb:4ZT1|rcsb pdb:4ZTE|rcsb pdb:6CXY|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|dip:DIP-477N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:N5rM8wI4ep+iZcnXU2g5wlJmJao9606	rogid:WI/yBLas6W5mlgbyOErqeeUFNA49606	rigid:w6au3f9T3ODpjqK4MsqlseqD5zg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P35221	uniprotkb:Q9H8V3	intact:EBI-701918|uniprotkb:Q12795|intact:EBI-7950809|intact:MINT-4924748|uniprotkb:Q8N1C0|ensembl:ENSP00000304669	intact:EBI-1054039|uniprotkb:Q9NSV8|uniprotkb:Q9NVW9|uniprotkb:Q0MT80|uniprotkb:Q6U836|uniprotkb:Q2M269|ensembl:ENSP00000376457	psi-mi:ctna1_human(display_long)|uniprotkb:Cadherin-associated protein(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-13(gene name synonym)|uniprotkb:CTNNA1(gene name)|psi-mi:CTNNA1(display_short)	psi-mi:ect2_human(display_long)|uniprotkb:Epithelial cell-transforming sequence 2 oncogene(gene name synonym)|uniprotkb:ECT2(gene name)|psi-mi:ECT2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ratheesh et al. (2012)	pubmed:22750944|doi:10.1038/ncb2532|imex:IM-25171	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15993390|imex:IM-25171-7|dip:DIP-200618E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001894.2|refseq:NP_001277236.1|refseq:NP_001277238.1|refseq:NP_001277239.1|refseq:NP_001277241.1|refseq:NP_001310911.1|refseq:NP_001310912.1|refseq:NP_001310913.1|refseq:NP_001310916.1|refseq:NP_001310917.1|refseq:NP_001310918.1|refseq:NP_001310919.1|refseq:NP_001310920.1|refseq:NP_001310921.1|refseq:NP_001310922.1|refseq:NP_001310923.1|refseq:NP_001310924.1|refseq:NP_001310925.1|refseq:NP_001310926.1|refseq:NP_001310927.1|refseq:NP_001310928.1|refseq:NP_001310929.1|dip:DIP-515N|ensembl:ENSG00000044115(gene)|ensembl:ENST00000302763(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P35221|rcsb pdb:1H6G|rcsb pdb:4EHP|rcsb pdb:4IGG|rcsb pdb:6UPV|rcsb pdb:6V2O|rcsb pdb:6V2P|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5626467	refseq:XP_011510816.1|refseq:NP_060568.3|refseq:NP_001245244.1|refseq:NP_001245245.1|ensembl:ENSG00000114346(gene)|ensembl:ENST00000392692(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007399"(nervous system development)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097149"(centralspindlin complex)|go:"GO:2000431"(regulation of cytokinesis, actomyosin contractile ring assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001357(BRCT)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036420|mint:Q9H8V3|rcsb pdb:3L46|rcsb pdb:4N40|rcsb pdb:6L30|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR026817|interpro:IPR035899|dip:DIP-47496N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:N5rM8wI4ep+iZcnXU2g5wlJmJao9606	rogid:ApqtJWU8n3b+PM8yUysFwFOkWuk9606	rigid:w6au3f9T3ODpjqK4MsqlseqD5zg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P35221	uniprotkb:Q9H8V3	intact:EBI-701918|uniprotkb:Q12795|intact:EBI-7950809|intact:MINT-4924748|uniprotkb:Q8N1C0|ensembl:ENSP00000304669	intact:EBI-1054039|uniprotkb:Q9NSV8|uniprotkb:Q9NVW9|uniprotkb:Q0MT80|uniprotkb:Q6U836|uniprotkb:Q2M269|ensembl:ENSP00000376457	psi-mi:ctna1_human(display_long)|uniprotkb:Cadherin-associated protein(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-13(gene name synonym)|uniprotkb:CTNNA1(gene name)|psi-mi:CTNNA1(display_short)	psi-mi:ect2_human(display_long)|uniprotkb:Epithelial cell-transforming sequence 2 oncogene(gene name synonym)|uniprotkb:ECT2(gene name)|psi-mi:ECT2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ratheesh et al. (2012)	pubmed:22750944|doi:10.1038/ncb2532|imex:IM-25171	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15993443|imex:IM-25171-10|dip:DIP-200621E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001894.2|refseq:NP_001277236.1|refseq:NP_001277238.1|refseq:NP_001277239.1|refseq:NP_001277241.1|refseq:NP_001310911.1|refseq:NP_001310912.1|refseq:NP_001310913.1|refseq:NP_001310916.1|refseq:NP_001310917.1|refseq:NP_001310918.1|refseq:NP_001310919.1|refseq:NP_001310920.1|refseq:NP_001310921.1|refseq:NP_001310922.1|refseq:NP_001310923.1|refseq:NP_001310924.1|refseq:NP_001310925.1|refseq:NP_001310926.1|refseq:NP_001310927.1|refseq:NP_001310928.1|refseq:NP_001310929.1|dip:DIP-515N|ensembl:ENSG00000044115(gene)|ensembl:ENST00000302763(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P35221|rcsb pdb:1H6G|rcsb pdb:4EHP|rcsb pdb:4IGG|rcsb pdb:6UPV|rcsb pdb:6V2O|rcsb pdb:6V2P|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5626467	refseq:XP_011510816.1|refseq:NP_060568.3|refseq:NP_001245244.1|refseq:NP_001245245.1|ensembl:ENSG00000114346(gene)|ensembl:ENST00000392692(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007399"(nervous system development)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097149"(centralspindlin complex)|go:"GO:2000431"(regulation of cytokinesis, actomyosin contractile ring assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001357(BRCT)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036420|mint:Q9H8V3|rcsb pdb:3L46|rcsb pdb:4N40|rcsb pdb:6L30|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR026817|interpro:IPR035899|dip:DIP-47496N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:N5rM8wI4ep+iZcnXU2g5wlJmJao9606	rogid:ApqtJWU8n3b+PM8yUysFwFOkWuk9606	rigid:VZYsTF1HoiuSXxxhJGfDWpPqXrs	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)