#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P02833	uniprotkb:P40427	intact:EBI-200869|intact:EBI-1629206|uniprotkb:Q95SZ6|ensemblmetazoa:FBpp0081161|ensemblmetazoa:FBpp0081162|ensemblmetazoa:FBpp0089245|ensemblmetazoa:FBpp0089246	intact:EBI-101537|uniprotkb:A4V4K5|uniprotkb:Q0KHS1|uniprotkb:Q9V3S2|ensemblmetazoa:FBpp0073940|ensemblmetazoa:FBpp0073942|ensemblmetazoa:FBpp0305514|ensemblmetazoa:FBpp0305515	psi-mi:antp_drome(display_long)|uniprotkb:Antp(gene name)|psi-mi:Antp(display_short)|uniprotkb:CG1028(orf name)	psi-mi:exd_drome(display_long)|uniprotkb:exd(gene name)|psi-mi:exd(display_short)|uniprotkb:CG8933(orf name)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Hudry et al. (2011)	pubmed:22745600|doi:10.1371/journal.pbio.1001351|imex:IM-18046	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15992547|imex:IM-18046-4|dip:DIP-189651E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_996176.1|flybase:FBgn0260642|refseq:NP_996167.1|refseq:NP_996168.1|refseq:NP_996170.1|refseq:NP_996175.1|dip:DIP-51405N|ensemblmetazoa:FBgn0260642(gene)|ensemblmetazoa:FBtr0081647(transcript)|ensemblmetazoa:FBtr0081652(transcript)|ensemblmetazoa:FBtr0081654(transcript)|ensemblmetazoa:FBtr0081655(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007383"(specification of segmental identity, antennal segment)|go:"GO:0007384"(specification of segmental identity, thorax)|go:"GO:0007419"(ventral cord development)|go:"GO:0007494"(midgut development)|go:"GO:0007507"(heart development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014019"(neuroblast development)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048542"(lymph gland development)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|rcsb pdb:1AHD|rcsb pdb:1HOM|rcsb pdb:1KZ0|rcsb pdb:1KZ5|rcsb pdb:1OMQ|rcsb pdb:1SAN|rcsb pdb:2HOA|rcsb pdb:2ND6|rcsb pdb:2ND7|rcsb pdb:2ND8|rcsb pdb:4XIC|rcsb pdb:4XID|rcsb pdb:5JLW|rcsb pdb:5JLX|rcsb pdb:9ANT	refseq:NP_523360.1|refseq:NP_727923.1|flybase:FBgn0000611|ensemblmetazoa:FBgn0000611(gene)|ensemblmetazoa:FBtr0074135(transcript)|ensemblmetazoa:FBtr0074137(transcript)|ensemblmetazoa:FBtr0333322(transcript)|ensemblmetazoa:FBtr0333323(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B8I|rcsb pdb:2R5Y|rcsb pdb:2R5Z|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT|refseq:NP_001259592.1|refseq:NP_001259593.1|dip:DIP-18773N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/07	2017/08/10	rogid:geGhJqYPEcOnpw1Nys1+5+t7Nu87227	rogid:BU1TH5bNahyZRxxL8K3gEzHJ4TE7227	rigid:Zq5j0xfW3JcveVWX1UeBCUjIEgo	false	venus fluorescent protein tag:n-n	mutation decreasing interaction strength:287-287|venus fluorescent protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10105	uniprotkb:P40427	intact:EBI-15992444|uniprotkb:O97065	intact:EBI-101537|uniprotkb:A4V4K5|uniprotkb:Q0KHS1|uniprotkb:Q9V3S2|ensemblmetazoa:FBpp0073940|ensemblmetazoa:FBpp0073942|ensemblmetazoa:FBpp0305514|ensemblmetazoa:FBpp0305515	psi-mi:lab_drome(display_long)|uniprotkb:lab(gene name)|psi-mi:lab(display_short)|uniprotkb:F24(gene name synonym)|uniprotkb:F90-2(gene name synonym)|uniprotkb:CG1264(orf name)	psi-mi:exd_drome(display_long)|uniprotkb:exd(gene name)|psi-mi:exd(display_short)|uniprotkb:CG8933(orf name)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Hudry et al. (2011)	pubmed:22745600|doi:10.1371/journal.pbio.1001351|imex:IM-18046	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15992474|imex:IM-18046-1|dip:DIP-189650E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001709"(cell fate determination)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007494"(midgut development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035284"(brain segmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060323"(head morphogenesis)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_476613.1|flybase:FBgn0002522|dip:DIP-59868N	refseq:NP_523360.1|refseq:NP_727923.1|flybase:FBgn0000611|ensemblmetazoa:FBgn0000611(gene)|ensemblmetazoa:FBtr0074135(transcript)|ensemblmetazoa:FBtr0074137(transcript)|ensemblmetazoa:FBtr0333322(transcript)|ensemblmetazoa:FBtr0333323(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B8I|rcsb pdb:2R5Y|rcsb pdb:2R5Z|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT|refseq:NP_001259592.1|refseq:NP_001259593.1|dip:DIP-18773N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/07	2017/08/10	rogid:oh0pd1Hrto07GdrtZt0B2iLuBPM7227	rogid:BU1TH5bNahyZRxxL8K3gEzHJ4TE7227	rigid:55O5D+gvSuiE4VO7Kb5eNo/vfWo	false	venus fluorescent protein tag:n-n	mutation decreasing interaction strength:287-287|venus fluorescent protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P09087	uniprotkb:P40427	intact:EBI-212384|uniprotkb:Q9VEQ8|uniprotkb:Q9VEQ9|ensemblmetazoa:FBpp0082826|ensemblmetazoa:FBpp0373669	intact:EBI-101537|uniprotkb:A4V4K5|uniprotkb:Q0KHS1|uniprotkb:Q9V3S2|ensemblmetazoa:FBpp0073940|ensemblmetazoa:FBpp0073942|ensemblmetazoa:FBpp0305514|ensemblmetazoa:FBpp0305515	psi-mi:abdb_drome(display_long)|uniprotkb:Abd-B(gene name)|psi-mi:Abd-B(display_short)|uniprotkb:CG10291(orf name)|uniprotkb:P3(gene name synonym)|uniprotkb:Infraabdominal 7(gene name synonym)|uniprotkb:PH189(gene name synonym)	psi-mi:exd_drome(display_long)|uniprotkb:exd(gene name)|psi-mi:exd(display_short)|uniprotkb:CG8933(orf name)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Hudry et al. (2011)	pubmed:22745600|doi:10.1371/journal.pbio.1001351|imex:IM-18046	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15992498|imex:IM-18046-2|dip:DIP-189653E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524896.2|refseq:NP_650577.1|refseq:NP_732180.1|refseq:NP_732181.1|refseq:NP_996220.1|flybase:FBgn0000015|refseq:NP_001303471.1|refseq:NP_001303472.1|refseq:NP_001303474.1|dip:DIP-19566N|ensemblmetazoa:FBgn0000015(gene)|ensemblmetazoa:FBtr0083384(transcript)|ensemblmetazoa:FBtr0415463(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007280"(pole cell migration)|go:"GO:0007379"(segment specification)|go:"GO:0007385"(specification of segmental identity, abdomen)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007486"(imaginal disc-derived female genitalia development)|go:"GO:0007494"(midgut development)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0007621"(negative regulation of female receptivity)|go:"GO:0008354"(germ cell migration)|go:"GO:0008584"(male gonad development)|go:"GO:0009997"(negative regulation of cardioblast cell fate specification)|go:"GO:0030539"(male genitalia development)|go:"GO:0030540"(female genitalia development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035261"(external genitalia morphogenesis)|go:"GO:0035263"(genital disc sexually dimorphic development)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0045705"(negative regulation of salivary gland boundary specification)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046693"(sperm storage)|go:"GO:0048094"(male pigmentation)|go:"GO:0061101"(neuroendocrine cell differentiation)|go:"GO:1902339"(positive regulation of apoptotic process involved in morphogenesis)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT	refseq:NP_523360.1|refseq:NP_727923.1|flybase:FBgn0000611|ensemblmetazoa:FBgn0000611(gene)|ensemblmetazoa:FBtr0074135(transcript)|ensemblmetazoa:FBtr0074137(transcript)|ensemblmetazoa:FBtr0333322(transcript)|ensemblmetazoa:FBtr0333323(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B8I|rcsb pdb:2R5Y|rcsb pdb:2R5Z|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT|refseq:NP_001259592.1|refseq:NP_001259593.1|dip:DIP-18773N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/07	2017/08/10	rogid:VC1V0+/TWK+I/iHM0/MiHjWqhSo7227	rogid:BU1TH5bNahyZRxxL8K3gEzHJ4TE7227	rigid:pWV0TCcDv7xFY1nqq0zO1KJqN8c	false	venus fluorescent protein tag:n-n	mutation disrupting interaction strength:287-287|venus fluorescent protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P41778	uniprotkb:P09632	intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519	intact:EBI-925374|ensembl:ENSMUSP00000052496|ensembl:ENSMUSP00000128136	psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym)	psi-mi:hxb8_mouse(display_long)|uniprotkb:Hoxb8(gene name)|psi-mi:Hoxb8(display_short)|uniprotkb:Hox-2.4(gene name synonym)|uniprotkb:Hoxb-8(gene name synonym)|uniprotkb:Homeobox protein Hox-2.4(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Hudry et al. (2011)	pubmed:22745600|doi:10.1371/journal.pbio.1001351|imex:IM-18046	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15992522|imex:IM-18046-3|dip:DIP-189655E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N	refseq:NP_034591.1|refseq:XP_017169784.1|refseq:XP_017169785.1|refseq:XP_017169786.1|dip:DIP-35618N|ensembl:ENSMUSG00000056648(gene)|ensembl:ENSMUST00000052650(transcript)|ensembl:ENSMUST00000168043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007625"(grooming behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479	psi-mi:"MI:0465"(dip)	comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation"	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	-	2017/08/07	2017/08/10	rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090	rogid:8LDO2u1q6tdrQsFLAfruV6oK7CE10090	rigid:ZEp2RmjuSxdtHsY2O5Zpx6xC7kc	false	venus fluorescent protein tag:n-n	mutation decreasing interaction strength:138-138,137-137|venus fluorescent protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P83949	uniprotkb:P40427	intact:EBI-202590|uniprotkb:P02834|uniprotkb:Q9TX83|uniprotkb:Q9VER4|uniprotkb:Q9VER5|ensemblmetazoa:FBpp0082793	intact:EBI-101537|uniprotkb:A4V4K5|uniprotkb:Q0KHS1|uniprotkb:Q9V3S2|ensemblmetazoa:FBpp0073940|ensemblmetazoa:FBpp0073942|ensemblmetazoa:FBpp0305514|ensemblmetazoa:FBpp0305515	psi-mi:ubx_drome(display_long)|uniprotkb:Ubx(gene name)|psi-mi:Ubx(display_short)|uniprotkb:CG10388(orf name)	psi-mi:exd_drome(display_long)|uniprotkb:exd(gene name)|psi-mi:exd(display_short)|uniprotkb:CG8933(orf name)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Hudry et al. (2011)	pubmed:22745600|doi:10.1371/journal.pbio.1001351|imex:IM-18046	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15992684|imex:IM-18046-9|dip:DIP-61785E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_536748.1|refseq:NP_536752.1|refseq:NP_732171.1|refseq:NP_732172.1|refseq:NP_732173.1|refseq:NP_996219.1|flybase:FBgn0003944|dip:DIP-33048N|ensemblmetazoa:FBgn0003944(gene)|ensemblmetazoa:FBtr0083347(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001706"(endoderm formation)|go:"GO:0001709"(cell fate determination)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007384"(specification of segmental identity, thorax)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007482"(haltere development)|go:"GO:0007494"(midgut development)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0007507"(heart development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010092"(specification of animal organ identity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035052"(dorsal vessel aortic cell fate commitment)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048636"(positive regulation of muscle organ development)|go:"GO:0060969"(obsolete negative regulation of gene silencing)|go:"GO:0061327"(anterior Malpighian tubule development)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1B8I|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:4UUT	refseq:NP_523360.1|refseq:NP_727923.1|flybase:FBgn0000611|ensemblmetazoa:FBgn0000611(gene)|ensemblmetazoa:FBtr0074135(transcript)|ensemblmetazoa:FBtr0074137(transcript)|ensemblmetazoa:FBtr0333322(transcript)|ensemblmetazoa:FBtr0333323(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B8I|rcsb pdb:2R5Y|rcsb pdb:2R5Z|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT|refseq:NP_001259592.1|refseq:NP_001259593.1|dip:DIP-18773N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/07	2017/08/10	rogid:PciTV5UxWTqbliI2WZAasPEr42g7227	rogid:BU1TH5bNahyZRxxL8K3gEzHJ4TE7227	rigid:M+fmYYjItm5I/cFREJYtr3DsNrM	false	venus fluorescent protein tag:n-n|mutation decreasing interaction strength:361-363,358-359	venus fluorescent protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P41778	uniprotkb:P09022-1	intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519	intact:EBI-15992645	psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym)	psi-mi:p09022-1(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Hudry et al. (2011)	pubmed:22745600|doi:10.1371/journal.pbio.1001351|imex:IM-18046	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15992657|imex:IM-18046-8|dip:DIP-189654E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N	intact:EBI-3957603(isoform-parent)	psi-mi:"MI:0465"(dip)	comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation"	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	-	2017/08/07	2017/08/10	rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090	rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090	rigid:es3m9MmEIzWUNFy7dGRHkmFeI1g	false	venus fluorescent protein tag:n-n	mutation decreasing interaction strength:204-204,203-203|venus fluorescent protein tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P83949	uniprotkb:P40427	intact:EBI-202590|uniprotkb:P02834|uniprotkb:Q9TX83|uniprotkb:Q9VER4|uniprotkb:Q9VER5|ensemblmetazoa:FBpp0082793	intact:EBI-101537|uniprotkb:A4V4K5|uniprotkb:Q0KHS1|uniprotkb:Q9V3S2|ensemblmetazoa:FBpp0073940|ensemblmetazoa:FBpp0073942|ensemblmetazoa:FBpp0305514|ensemblmetazoa:FBpp0305515	psi-mi:ubx_drome(display_long)|uniprotkb:Ubx(gene name)|psi-mi:Ubx(display_short)|uniprotkb:CG10388(orf name)	psi-mi:exd_drome(display_long)|uniprotkb:exd(gene name)|psi-mi:exd(display_short)|uniprotkb:CG8933(orf name)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Hudry et al. (2011)	pubmed:22745600|doi:10.1371/journal.pbio.1001351|imex:IM-18046	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15992621|imex:IM-18046-7|dip:DIP-61785E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_536748.1|refseq:NP_536752.1|refseq:NP_732171.1|refseq:NP_732172.1|refseq:NP_732173.1|refseq:NP_996219.1|flybase:FBgn0003944|dip:DIP-33048N|ensemblmetazoa:FBgn0003944(gene)|ensemblmetazoa:FBtr0083347(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001706"(endoderm formation)|go:"GO:0001709"(cell fate determination)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007384"(specification of segmental identity, thorax)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007482"(haltere development)|go:"GO:0007494"(midgut development)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0007507"(heart development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010092"(specification of animal organ identity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035052"(dorsal vessel aortic cell fate commitment)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048636"(positive regulation of muscle organ development)|go:"GO:0060969"(obsolete negative regulation of gene silencing)|go:"GO:0061327"(anterior Malpighian tubule development)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1B8I|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:4UUT	refseq:NP_523360.1|refseq:NP_727923.1|flybase:FBgn0000611|ensemblmetazoa:FBgn0000611(gene)|ensemblmetazoa:FBtr0074135(transcript)|ensemblmetazoa:FBtr0074137(transcript)|ensemblmetazoa:FBtr0333322(transcript)|ensemblmetazoa:FBtr0333323(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B8I|rcsb pdb:2R5Y|rcsb pdb:2R5Z|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT|refseq:NP_001259592.1|refseq:NP_001259593.1|dip:DIP-18773N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/07	2017/08/10	rogid:PciTV5UxWTqbliI2WZAasPEr42g7227	rogid:BU1TH5bNahyZRxxL8K3gEzHJ4TE7227	rigid:M+fmYYjItm5I/cFREJYtr3DsNrM	false	venus fluorescent protein tag:n-n	mutation decreasing interaction strength:287-287|venus fluorescent protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P41778	uniprotkb:P09632	intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519	intact:EBI-925374|ensembl:ENSMUSP00000052496|ensembl:ENSMUSP00000128136	psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym)	psi-mi:hxb8_mouse(display_long)|uniprotkb:Hoxb8(gene name)|psi-mi:Hoxb8(display_short)|uniprotkb:Hox-2.4(gene name synonym)|uniprotkb:Hoxb-8(gene name synonym)|uniprotkb:Homeobox protein Hox-2.4(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Hudry et al. (2011)	pubmed:22745600|doi:10.1371/journal.pbio.1001351|imex:IM-18046	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15992597|imex:IM-18046-6|dip:DIP-189655E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N	refseq:NP_034591.1|refseq:XP_017169784.1|refseq:XP_017169785.1|refseq:XP_017169786.1|dip:DIP-35618N|ensembl:ENSMUSG00000056648(gene)|ensembl:ENSMUST00000052650(transcript)|ensembl:ENSMUST00000168043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007625"(grooming behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479	psi-mi:"MI:0465"(dip)	comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation"	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	-	2017/08/07	2017/08/10	rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090	rogid:8LDO2u1q6tdrQsFLAfruV6oK7CE10090	rigid:ZEp2RmjuSxdtHsY2O5Zpx6xC7kc	false	venus fluorescent protein tag:n-n|mutation disrupting interaction strength:282-282	venus fluorescent protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P41778	uniprotkb:P09631	intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519	intact:EBI-925334|uniprotkb:O70154|uniprotkb:O70155|ensembl:ENSMUSP00000046939	psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym)	psi-mi:hxa9_mouse(display_long)|uniprotkb:Hoxa9(gene name)|psi-mi:Hoxa9(display_short)|uniprotkb:Hox-1.7(gene name synonym)|uniprotkb:Hoxa-9(gene name synonym)|uniprotkb:Homeobox protein Hox-1.7(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Hudry et al. (2011)	pubmed:22745600|doi:10.1371/journal.pbio.1001351|imex:IM-18046	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15992708|imex:IM-18046-10|dip:DIP-70652E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N	refseq:NP_034586.1|dip:DIP-35619N|ensembl:ENSMUSG00000038227(gene)|ensembl:ENSMUST00000048680(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030879"(mammary gland development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0060065"(uterus development)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1PUF	psi-mi:"MI:0465"(dip)	comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation"	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	-	2017/08/07	2017/08/10	rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090	rogid:OjGwxaxJEuDgDykwUs76pvyWuvU10090	rigid:FcU1+cA7LqjZ/kE9f54pbDOm+VE	false	venus fluorescent protein tag:n-n	venus fluorescent protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10105	uniprotkb:P40427	intact:EBI-15992444|uniprotkb:O97065	intact:EBI-101537|uniprotkb:A4V4K5|uniprotkb:Q0KHS1|uniprotkb:Q9V3S2|ensemblmetazoa:FBpp0073940|ensemblmetazoa:FBpp0073942|ensemblmetazoa:FBpp0305514|ensemblmetazoa:FBpp0305515	psi-mi:lab_drome(display_long)|uniprotkb:lab(gene name)|psi-mi:lab(display_short)|uniprotkb:F24(gene name synonym)|uniprotkb:F90-2(gene name synonym)|uniprotkb:CG1264(orf name)	psi-mi:exd_drome(display_long)|uniprotkb:exd(gene name)|psi-mi:exd(display_short)|uniprotkb:CG8933(orf name)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Hudry et al. (2011)	pubmed:22745600|doi:10.1371/journal.pbio.1001351|imex:IM-18046	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15992571|imex:IM-18046-5|dip:DIP-189650E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001709"(cell fate determination)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007494"(midgut development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035284"(brain segmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060323"(head morphogenesis)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_476613.1|flybase:FBgn0002522|dip:DIP-59868N	refseq:NP_523360.1|refseq:NP_727923.1|flybase:FBgn0000611|ensemblmetazoa:FBgn0000611(gene)|ensemblmetazoa:FBtr0074135(transcript)|ensemblmetazoa:FBtr0074137(transcript)|ensemblmetazoa:FBtr0333322(transcript)|ensemblmetazoa:FBtr0333323(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B8I|rcsb pdb:2R5Y|rcsb pdb:2R5Z|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT|refseq:NP_001259592.1|refseq:NP_001259593.1|dip:DIP-18773N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/07	2017/08/10	rogid:oh0pd1Hrto07GdrtZt0B2iLuBPM7227	rogid:BU1TH5bNahyZRxxL8K3gEzHJ4TE7227	rigid:55O5D+gvSuiE4VO7Kb5eNo/vfWo	false	venus fluorescent protein tag:n-n|mutation decreasing interaction strength:395-395,394-394,393-393	venus fluorescent protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P29555	uniprotkb:P40427	intact:EBI-201507|uniprotkb:Q5U161|uniprotkb:Q9VER1|ensemblmetazoa:FBpp0082829	intact:EBI-101537|uniprotkb:A4V4K5|uniprotkb:Q0KHS1|uniprotkb:Q9V3S2|ensemblmetazoa:FBpp0073940|ensemblmetazoa:FBpp0073942|ensemblmetazoa:FBpp0305514|ensemblmetazoa:FBpp0305515	psi-mi:abda_drome(display_long)|uniprotkb:abd-A(gene name)|psi-mi:abd-A(display_short)|uniprotkb:CG10325(orf name)	psi-mi:exd_drome(display_long)|uniprotkb:exd(gene name)|psi-mi:exd(display_short)|uniprotkb:CG8933(orf name)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Hudry et al. (2011)	pubmed:22745600|doi:10.1371/journal.pbio.1001351|imex:IM-18046	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15992802|imex:IM-18046-14|dip:DIP-189652E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001163632.1|refseq:NP_476693.1|refseq:NP_732176.1|flybase:FBgn0000014|refseq:NP_001247145.1|dip:DIP-17987N|ensemblmetazoa:FBgn0000014(gene)|ensemblmetazoa:FBtr0083388(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001742"(oenocyte differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007280"(pole cell migration)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007438"(oenocyte development)|go:"GO:0007494"(midgut development)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008354"(germ cell migration)|go:"GO:0008406"(gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0014019"(neuroblast development)|go:"GO:0035053"(dorsal vessel heart proper cell fate commitment)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048636"(positive regulation of muscle organ development)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0048806"(genitalia development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022132	refseq:NP_523360.1|refseq:NP_727923.1|flybase:FBgn0000611|ensemblmetazoa:FBgn0000611(gene)|ensemblmetazoa:FBtr0074135(transcript)|ensemblmetazoa:FBtr0074137(transcript)|ensemblmetazoa:FBtr0333322(transcript)|ensemblmetazoa:FBtr0333323(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B8I|rcsb pdb:2R5Y|rcsb pdb:2R5Z|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT|refseq:NP_001259592.1|refseq:NP_001259593.1|dip:DIP-18773N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/07	2017/08/10	rogid:CUVIdePTLQpatmgnFaiLk4p8+N07227	rogid:BU1TH5bNahyZRxxL8K3gEzHJ4TE7227	rigid:XvfDxyMtkygK8xQ9pCe77/kM+9g	false	venus fluorescent protein tag:n-n|mutation decreasing interaction strength:377-377,376-376,375-375|mutation decreasing interaction strength:465-465,464-464,463-463,462-462	venus fluorescent protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P41778	uniprotkb:P09632	intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519	intact:EBI-925374|ensembl:ENSMUSP00000052496|ensembl:ENSMUSP00000128136	psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym)	psi-mi:hxb8_mouse(display_long)|uniprotkb:Hoxb8(gene name)|psi-mi:Hoxb8(display_short)|uniprotkb:Hox-2.4(gene name synonym)|uniprotkb:Hoxb-8(gene name synonym)|uniprotkb:Homeobox protein Hox-2.4(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Hudry et al. (2011)	pubmed:22745600|doi:10.1371/journal.pbio.1001351|imex:IM-18046	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15992777|imex:IM-18046-13|dip:DIP-189655E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N	refseq:NP_034591.1|refseq:XP_017169784.1|refseq:XP_017169785.1|refseq:XP_017169786.1|dip:DIP-35618N|ensembl:ENSMUSG00000056648(gene)|ensembl:ENSMUST00000052650(transcript)|ensembl:ENSMUST00000168043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007625"(grooming behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479	psi-mi:"MI:0465"(dip)	comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation"	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	-	2017/08/07	2017/08/10	rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090	rogid:8LDO2u1q6tdrQsFLAfruV6oK7CE10090	rigid:ZEp2RmjuSxdtHsY2O5Zpx6xC7kc	false	venus fluorescent protein tag:n-n	mutation decreasing interaction strength:138-138,137-137|venus fluorescent protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P29555	uniprotkb:P40427	intact:EBI-201507|uniprotkb:Q5U161|uniprotkb:Q9VER1|ensemblmetazoa:FBpp0082829	intact:EBI-101537|uniprotkb:A4V4K5|uniprotkb:Q0KHS1|uniprotkb:Q9V3S2|ensemblmetazoa:FBpp0073940|ensemblmetazoa:FBpp0073942|ensemblmetazoa:FBpp0305514|ensemblmetazoa:FBpp0305515	psi-mi:abda_drome(display_long)|uniprotkb:abd-A(gene name)|psi-mi:abd-A(display_short)|uniprotkb:CG10325(orf name)	psi-mi:exd_drome(display_long)|uniprotkb:exd(gene name)|psi-mi:exd(display_short)|uniprotkb:CG8933(orf name)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Hudry et al. (2011)	pubmed:22745600|doi:10.1371/journal.pbio.1001351|imex:IM-18046	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15992753|imex:IM-18046-12|dip:DIP-189652E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001163632.1|refseq:NP_476693.1|refseq:NP_732176.1|flybase:FBgn0000014|refseq:NP_001247145.1|dip:DIP-17987N|ensemblmetazoa:FBgn0000014(gene)|ensemblmetazoa:FBtr0083388(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001742"(oenocyte differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007280"(pole cell migration)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007438"(oenocyte development)|go:"GO:0007494"(midgut development)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008354"(germ cell migration)|go:"GO:0008406"(gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0014019"(neuroblast development)|go:"GO:0035053"(dorsal vessel heart proper cell fate commitment)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048636"(positive regulation of muscle organ development)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0048806"(genitalia development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022132	refseq:NP_523360.1|refseq:NP_727923.1|flybase:FBgn0000611|ensemblmetazoa:FBgn0000611(gene)|ensemblmetazoa:FBtr0074135(transcript)|ensemblmetazoa:FBtr0074137(transcript)|ensemblmetazoa:FBtr0333322(transcript)|ensemblmetazoa:FBtr0333323(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B8I|rcsb pdb:2R5Y|rcsb pdb:2R5Z|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT|refseq:NP_001259592.1|refseq:NP_001259593.1|dip:DIP-18773N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/07	2017/08/10	rogid:CUVIdePTLQpatmgnFaiLk4p8+N07227	rogid:BU1TH5bNahyZRxxL8K3gEzHJ4TE7227	rigid:XvfDxyMtkygK8xQ9pCe77/kM+9g	false	venus fluorescent protein tag:n-n	mutation decreasing interaction strength:287-287|venus fluorescent protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P09077	uniprotkb:P40427	intact:EBI-666569|uniprotkb:Q23990|uniprotkb:Q24508|uniprotkb:Q9V3Q3|ensemblmetazoa:FBpp0081163|ensemblmetazoa:FBpp0089393	intact:EBI-101537|uniprotkb:A4V4K5|uniprotkb:Q0KHS1|uniprotkb:Q9V3S2|ensemblmetazoa:FBpp0073940|ensemblmetazoa:FBpp0073942|ensemblmetazoa:FBpp0305514|ensemblmetazoa:FBpp0305515	psi-mi:scr_drome(display_long)|uniprotkb:Scr(gene name)|psi-mi:Scr(display_short)|uniprotkb:CG1030(orf name)	psi-mi:exd_drome(display_long)|uniprotkb:exd(gene name)|psi-mi:exd(display_short)|uniprotkb:CG8933(orf name)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Hudry et al. (2011)	pubmed:22745600|doi:10.1371/journal.pbio.1001351|imex:IM-18046	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15992729|imex:IM-18046-11|dip:DIP-68062E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524248.2|refseq:NP_996165.1|flybase:FBgn0003339|dip:DIP-40017N|ensemblmetazoa:FBgn0003339(gene)|ensemblmetazoa:FBtr0081657(transcript)|ensemblmetazoa:FBtr0081658(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007494"(midgut development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045498"(sex comb development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|rcsb pdb:2R5Y|rcsb pdb:2R5Z	refseq:NP_523360.1|refseq:NP_727923.1|flybase:FBgn0000611|ensemblmetazoa:FBgn0000611(gene)|ensemblmetazoa:FBtr0074135(transcript)|ensemblmetazoa:FBtr0074137(transcript)|ensemblmetazoa:FBtr0333322(transcript)|ensemblmetazoa:FBtr0333323(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B8I|rcsb pdb:2R5Y|rcsb pdb:2R5Z|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT|refseq:NP_001259592.1|refseq:NP_001259593.1|dip:DIP-18773N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/07	2017/08/10	rogid:z5Lj6W1yKerSXCkC3CX96vECd507227	rogid:BU1TH5bNahyZRxxL8K3gEzHJ4TE7227	rigid:p3Jky7oQNHF4HFdb/wzWdZTVKyk	false	venus fluorescent protein tag:n-n	mutation disrupting interaction strength:287-287|venus fluorescent protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P09077	uniprotkb:P40427	intact:EBI-666569|uniprotkb:Q23990|uniprotkb:Q24508|uniprotkb:Q9V3Q3|ensemblmetazoa:FBpp0081163|ensemblmetazoa:FBpp0089393	intact:EBI-101537|uniprotkb:A4V4K5|uniprotkb:Q0KHS1|uniprotkb:Q9V3S2|ensemblmetazoa:FBpp0073940|ensemblmetazoa:FBpp0073942|ensemblmetazoa:FBpp0305514|ensemblmetazoa:FBpp0305515	psi-mi:scr_drome(display_long)|uniprotkb:Scr(gene name)|psi-mi:Scr(display_short)|uniprotkb:CG1030(orf name)	psi-mi:exd_drome(display_long)|uniprotkb:exd(gene name)|psi-mi:exd(display_short)|uniprotkb:CG8933(orf name)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Hudry et al. (2011)	pubmed:22745600|doi:10.1371/journal.pbio.1001351|imex:IM-18046	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15992834|imex:IM-18046-15|dip:DIP-68062E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524248.2|refseq:NP_996165.1|flybase:FBgn0003339|dip:DIP-40017N|ensemblmetazoa:FBgn0003339(gene)|ensemblmetazoa:FBtr0081657(transcript)|ensemblmetazoa:FBtr0081658(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007494"(midgut development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045498"(sex comb development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|rcsb pdb:2R5Y|rcsb pdb:2R5Z	refseq:NP_523360.1|refseq:NP_727923.1|flybase:FBgn0000611|ensemblmetazoa:FBgn0000611(gene)|ensemblmetazoa:FBtr0074135(transcript)|ensemblmetazoa:FBtr0074137(transcript)|ensemblmetazoa:FBtr0333322(transcript)|ensemblmetazoa:FBtr0333323(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B8I|rcsb pdb:2R5Y|rcsb pdb:2R5Z|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT|refseq:NP_001259592.1|refseq:NP_001259593.1|dip:DIP-18773N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/07	2017/08/10	rogid:z5Lj6W1yKerSXCkC3CX96vECd507227	rogid:BU1TH5bNahyZRxxL8K3gEzHJ4TE7227	rigid:p3Jky7oQNHF4HFdb/wzWdZTVKyk	false	venus fluorescent protein tag:n-n|mutation decreasing interaction strength:308-308,307-307,306-306,305-305	venus fluorescent protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P41778	uniprotkb:P09023	intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519	intact:EBI-15992861|ensembl:ENSMUSP00000000704|ensembl:ENSMUSP00000133281	psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym)	psi-mi:hxb6_mouse(display_long)|uniprotkb:Hoxb6(gene name)|psi-mi:Hoxb6(display_short)|uniprotkb:Hox-2.2(gene name synonym)|uniprotkb:Hoxb-6(gene name synonym)|uniprotkb:Homeobox protein Hox-2.2(gene name synonym)|uniprotkb:Homeobox protein MH-22A(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Hudry et al. (2011)	pubmed:22745600|doi:10.1371/journal.pbio.1001351|imex:IM-18046	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15992892|imex:IM-18046-16|dip:DIP-189656E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N	ensembl:ENSMUSG00000000690(gene)|ensembl:ENSMUST00000000704(transcript)|ensembl:ENSMUST00000173432(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|refseq:NP_032295.1|dip:DIP-59870N	psi-mi:"MI:0465"(dip)	comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation"	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	-	2017/08/07	2017/08/10	rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090	rogid:yLbga2gC2JdNQr6AIx3K736hL7o10090	rigid:UZbRAv6c5DxYVwbVT8BwwT4ykm8	false	venus fluorescent protein tag:n-n	venus fluorescent protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)