#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P06727	uniprotkb:P06727	intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425	intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425	psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym)	psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Deng et al. (2012)	pubmed:22579246|doi:10.1016/j.str.2012.02.020|imex:IM-18013	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15983229|imex:IM-18013-1|dip:DIP-189609E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis)	refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2020/06/18	rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606	rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606	rigid:egQxVP8Udk20enM81bwGvjzOnSQ	false	cross linker:104-104|sufficient binding region:84-355	cross linker:97-97|sufficient binding region:84-355	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06727	uniprotkb:P06727	intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425	intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425	psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym)	psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Deng et al. (2012)	pubmed:22579246|doi:10.1016/j.str.2012.02.020|imex:IM-18013	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15983273|imex:IM-18013-3|dip:DIP-189609E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis)	refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2020/06/18	rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606	rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606	rigid:ZFW0cJyhaW6u7uGpzLjyLLiMBVw	false	sufficient binding region:84-355|mutation disrupting interaction strength:184-184,183-183,182-182	sufficient binding region:84-355|mutation disrupting interaction strength:184-184,183-183,182-182	-	0	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P06727	uniprotkb:P06727	intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425	intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425	psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym)	psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Deng et al. (2012)	pubmed:22579246|doi:10.1016/j.str.2012.02.020|imex:IM-18013	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15983296|imex:IM-18013-4|dip:DIP-189609E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis)	refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2020/06/18	rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606	rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606	rigid:egQxVP8Udk20enM81bwGvjzOnSQ	false	cross linker:198-198|sufficient binding region:84-355	cross linker:253-253|sufficient binding region:84-355	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06727	uniprotkb:P06727	intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425	intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425	psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym)	psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Deng et al. (2012)	pubmed:22579246|doi:10.1016/j.str.2012.02.020|imex:IM-18013	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15983411|imex:IM-18013-9|dip:DIP-189609E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis)	refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2020/06/18	rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606	rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606	rigid:ZFW0cJyhaW6u7uGpzLjyLLiMBVw	false	mutation:171-171	mutation:171-171	-	0	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P06727	uniprotkb:P06727	intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425	intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425	psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym)	psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Deng et al. (2012)	pubmed:22579246|doi:10.1016/j.str.2012.02.020|imex:IM-18013	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15983346|imex:IM-18013-6|dip:DIP-189609E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis)	refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2020/06/18	rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606	rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606	rigid:ZFW0cJyhaW6u7uGpzLjyLLiMBVw	false	sufficient binding region:84-355|mutation disrupting interaction strength:184-184,183-183,182-182	sufficient binding region:84-355|mutation disrupting interaction strength:184-184,183-183,182-182	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06727	uniprotkb:P06727	intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425	intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425	psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym)	psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Deng et al. (2012)	pubmed:22579246|doi:10.1016/j.str.2012.02.020|imex:IM-18013	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15983369|imex:IM-18013-7|dip:DIP-189609E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis)	refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2020/06/18	rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606	rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606	rigid:ZFW0cJyhaW6u7uGpzLjyLLiMBVw	false	mutation:283-283	mutation:283-283	-	0	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P06727	uniprotkb:P06727	intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425	intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425	psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym)	psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym)	psi-mi:"MI:0028"(cosedimentation in solution)	Deng et al. (2012)	pubmed:22579246|doi:10.1016/j.str.2012.02.020|imex:IM-18013	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15983388|imex:IM-18013-8|dip:DIP-189609E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis)	refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2020/06/18	rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606	rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606	rigid:ZFW0cJyhaW6u7uGpzLjyLLiMBVw	false	sufficient binding region:84-355|mutation disrupting interaction strength:184-184,183-183,182-182	sufficient binding region:84-355|mutation disrupting interaction strength:184-184,183-183,182-182	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06727	uniprotkb:P06727	intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425	intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425	psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym)	psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Deng et al. (2012)	pubmed:22579246|doi:10.1016/j.str.2012.02.020|imex:IM-18013	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15983255|imex:IM-18013-2|dip:DIP-189609E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis)	refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2020/06/18	rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606	rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606	rigid:ZFW0cJyhaW6u7uGpzLjyLLiMBVw	false	sufficient binding region:84-355	sufficient binding region:84-355	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06727	uniprotkb:P06727	intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425	intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425	psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym)	psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Deng et al. (2012)	pubmed:22579246|doi:10.1016/j.str.2012.02.020|imex:IM-18013	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15983321|imex:IM-18013-5|dip:DIP-189609E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis)	refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2020/06/18	rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606	rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606	rigid:egQxVP8Udk20enM81bwGvjzOnSQ	false	cross linker:99-99|sufficient binding region:84-355	cross linker:247-247|sufficient binding region:84-355	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06727	uniprotkb:P06727	intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425	intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425	psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym)	psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Deng et al. (2012)	pubmed:22579246|doi:10.1016/j.str.2012.02.020|imex:IM-18013	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15983430|imex:IM-18013-10|dip:DIP-189609E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis)	refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2020/06/18	rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606	rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606	rigid:egQxVP8Udk20enM81bwGvjzOnSQ	false	cross linker:209-209|sufficient binding region:84-355	cross linker:247-247|sufficient binding region:84-355	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)