#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q14678	uniprotkb:Q7Z4S6	intact:EBI-2556221|uniprotkb:Q8IY65|uniprotkb:Q8WX74|uniprotkb:Q5W0W0|uniprotkb:D3DRH3|ensembl:ENSP00000501167|ensembl:ENSP00000371734|ensembl:ENSP00000371740|ensembl:ENSP00000477725|uniprotkb:A2A2W8	intact:EBI-2691397|intact:EBI-11051686|uniprotkb:Q9C0F5|uniprotkb:Q9Y590|uniprotkb:Q86WZ5|uniprotkb:Q8IVZ8|uniprotkb:Q9NXU4|uniprotkb:B0I1R9|uniprotkb:A8MX28|uniprotkb:Q7Z668|uniprotkb:Q6UKL9|uniprotkb:B9EGE4|uniprotkb:F5H0C3|uniprotkb:F5H219|uniprotkb:Q2UVF1|intact:EBI-28975118|ensembl:ENSP00000354878	psi-mi:kank1_human(display_long)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)	psi-mi:ki21a_human(display_long)|uniprotkb:KIAA1708(gene name synonym)|uniprotkb:KIF2(gene name synonym)|uniprotkb:Kinesin-like protein KIF2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-62(gene name synonym)|uniprotkb:KIF21A(gene name)|psi-mi:KIF21A(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:22084092|doi:10.1073/pnas.1117011108|imex:IM-17951	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953570|imex:IM-17951-1|dip:DIP-189477E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-56491N|refseq:NP_055973.2|ensembl:ENST00000382297(transcript)|ensembl:ENST00000382303(transcript)|ensembl:ENST00000619269(transcript)|ensembl:ENST00000674102(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|rcsb pdb:5YBJ|rcsb pdb:5YBU|reactome:R-HSA-9018519|reactome:R-HSA-9673768|ensembl:ENSG00000107104(gene)|refseq:NP_001243805.1|refseq:NP_001243806.1|refseq:XP_016870003.1|refseq:XP_016870004.1|refseq:XP_016870016.1|refseq:XP_016870017.1|refseq:XP_016870018.1|refseq:XP_016870019.1|refseq:NP_694856.1	ensembl:ENSP00000354878|ensembl:ENST00000361961|ensembl:ENSP00000354851|ensembl:ENST00000541463|ensembl:ENSP00000438075|ensembl:ENST00000544797|ensembl:ENSP00000445606|refseq:NP_001166934.1|refseq:NP_001166935.1|refseq:NP_001166936.1|refseq:NP_060111.2|refseq:XP_005269064.1|refseq:XP_005269070.1|ensembl:ENSG00000139116(gene)|ensembl:ENST00000361418(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:1990939"|interpro:IPR001680(WD40 repeat)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036322|interpro:IPR036961|rcsb pdb:5D3A|rcsb pdb:5NFD|rcsb pdb:5YBU|rcsb pdb:5YBV|rcsb pdb:7KLJ|reactome:R-HSA-6811434|reactome:R-HSA-983189|dip:DIP-56253N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:+TXNlWTBf1g8b+TpaR9KiM9f+b89606	rogid:GRF+n9Srey50s4v6s2Z2E23/x0s9606	rigid:lgqeVVdrX03yWD1JvesPzJOeXEg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14678	uniprotkb:Q9Y6D6	intact:EBI-2556221|uniprotkb:Q8IY65|uniprotkb:Q8WX74|uniprotkb:Q5W0W0|uniprotkb:D3DRH3|ensembl:ENSP00000501167|ensembl:ENSP00000371734|ensembl:ENSP00000371740|ensembl:ENSP00000477725|uniprotkb:A2A2W8	intact:EBI-1044254|uniprotkb:Q9NV46|uniprotkb:Q9UFV2|uniprotkb:Q9UNL0|ensembl:ENSP00000262215	psi-mi:kank1_human(display_long)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)	psi-mi:big1_human(display_long)|uniprotkb:ARFGEF1(gene name)|psi-mi:ARFGEF1(display_short)|uniprotkb:ARFGEP1(gene name synonym)|uniprotkb:BIG1(gene name synonym)|uniprotkb:p200 ARF-GEP1(gene name synonym)|uniprotkb:p200 ARF guanine nucleotide exchange factor(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:22084092|doi:10.1073/pnas.1117011108|imex:IM-17951	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953570|imex:IM-17951-1|dip:DIP-189477E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-56491N|refseq:NP_055973.2|ensembl:ENST00000382297(transcript)|ensembl:ENST00000382303(transcript)|ensembl:ENST00000619269(transcript)|ensembl:ENST00000674102(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|rcsb pdb:5YBJ|rcsb pdb:5YBU|reactome:R-HSA-9018519|reactome:R-HSA-9673768|ensembl:ENSG00000107104(gene)|refseq:NP_001243805.1|refseq:NP_001243806.1|refseq:XP_016870003.1|refseq:XP_016870004.1|refseq:XP_016870016.1|refseq:XP_016870017.1|refseq:XP_016870018.1|refseq:XP_016870019.1|refseq:NP_694856.1	ensembl:ENSG00000066777(gene)|ensembl:ENST00000262215(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007030"(Golgi organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017022"(myosin binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090284"(positive regulation of protein glycosylation in Golgi)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|mint:Q9Y6D6|rcsb pdb:3LTL|rcsb pdb:5EE5|rcsb pdb:5J5C|go:"GO:0051897"(positive regulation of protein kinase B signaling)|refseq:NP_006412.2|refseq:XP_005251191.1|dip:DIP-29748N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:+TXNlWTBf1g8b+TpaR9KiM9f+b89606	rogid:HIXdg7zEoEpHcC+KwTUjNFSgr5M9606	rigid:lgqeVVdrX03yWD1JvesPzJOeXEg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y6D6	uniprotkb:Q7Z4S6	intact:EBI-1044254|uniprotkb:Q9NV46|uniprotkb:Q9UFV2|uniprotkb:Q9UNL0|ensembl:ENSP00000262215	intact:EBI-2691397|intact:EBI-11051686|uniprotkb:Q9C0F5|uniprotkb:Q9Y590|uniprotkb:Q86WZ5|uniprotkb:Q8IVZ8|uniprotkb:Q9NXU4|uniprotkb:B0I1R9|uniprotkb:A8MX28|uniprotkb:Q7Z668|uniprotkb:Q6UKL9|uniprotkb:B9EGE4|uniprotkb:F5H0C3|uniprotkb:F5H219|uniprotkb:Q2UVF1|intact:EBI-28975118|ensembl:ENSP00000354878	psi-mi:big1_human(display_long)|uniprotkb:ARFGEF1(gene name)|psi-mi:ARFGEF1(display_short)|uniprotkb:ARFGEP1(gene name synonym)|uniprotkb:BIG1(gene name synonym)|uniprotkb:p200 ARF-GEP1(gene name synonym)|uniprotkb:p200 ARF guanine nucleotide exchange factor(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 1(gene name synonym)	psi-mi:ki21a_human(display_long)|uniprotkb:KIAA1708(gene name synonym)|uniprotkb:KIF2(gene name synonym)|uniprotkb:Kinesin-like protein KIF2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-62(gene name synonym)|uniprotkb:KIF21A(gene name)|psi-mi:KIF21A(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:22084092|doi:10.1073/pnas.1117011108|imex:IM-17951	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953606|imex:IM-17951-3|dip:DIP-189476E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000066777(gene)|ensembl:ENST00000262215(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007030"(Golgi organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017022"(myosin binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090284"(positive regulation of protein glycosylation in Golgi)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|mint:Q9Y6D6|rcsb pdb:3LTL|rcsb pdb:5EE5|rcsb pdb:5J5C|go:"GO:0051897"(positive regulation of protein kinase B signaling)|refseq:NP_006412.2|refseq:XP_005251191.1|dip:DIP-29748N	ensembl:ENSP00000354878|ensembl:ENST00000361961|ensembl:ENSP00000354851|ensembl:ENST00000541463|ensembl:ENSP00000438075|ensembl:ENST00000544797|ensembl:ENSP00000445606|refseq:NP_001166934.1|refseq:NP_001166935.1|refseq:NP_001166936.1|refseq:NP_060111.2|refseq:XP_005269064.1|refseq:XP_005269070.1|ensembl:ENSG00000139116(gene)|ensembl:ENST00000361418(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:1990939"|interpro:IPR001680(WD40 repeat)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036322|interpro:IPR036961|rcsb pdb:5D3A|rcsb pdb:5NFD|rcsb pdb:5YBU|rcsb pdb:5YBV|rcsb pdb:7KLJ|reactome:R-HSA-6811434|reactome:R-HSA-983189|dip:DIP-56253N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:HIXdg7zEoEpHcC+KwTUjNFSgr5M9606	rogid:GRF+n9Srey50s4v6s2Z2E23/x0s9606	rigid:xVclB/UK2JIKvH9HSSa+OOq2H5w	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y6D6	uniprotkb:Q14678	intact:EBI-1044254|uniprotkb:Q9NV46|uniprotkb:Q9UFV2|uniprotkb:Q9UNL0|ensembl:ENSP00000262215	intact:EBI-2556221|uniprotkb:Q8IY65|uniprotkb:Q8WX74|uniprotkb:Q5W0W0|uniprotkb:D3DRH3|ensembl:ENSP00000501167|ensembl:ENSP00000371734|ensembl:ENSP00000371740|ensembl:ENSP00000477725|uniprotkb:A2A2W8	psi-mi:big1_human(display_long)|uniprotkb:ARFGEF1(gene name)|psi-mi:ARFGEF1(display_short)|uniprotkb:ARFGEP1(gene name synonym)|uniprotkb:BIG1(gene name synonym)|uniprotkb:p200 ARF-GEP1(gene name synonym)|uniprotkb:p200 ARF guanine nucleotide exchange factor(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 1(gene name synonym)	psi-mi:kank1_human(display_long)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:22084092|doi:10.1073/pnas.1117011108|imex:IM-17951	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953606|imex:IM-17951-3|dip:DIP-189476E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000066777(gene)|ensembl:ENST00000262215(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007030"(Golgi organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017022"(myosin binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090284"(positive regulation of protein glycosylation in Golgi)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|mint:Q9Y6D6|rcsb pdb:3LTL|rcsb pdb:5EE5|rcsb pdb:5J5C|go:"GO:0051897"(positive regulation of protein kinase B signaling)|refseq:NP_006412.2|refseq:XP_005251191.1|dip:DIP-29748N	dip:DIP-56491N|refseq:NP_055973.2|ensembl:ENST00000382297(transcript)|ensembl:ENST00000382303(transcript)|ensembl:ENST00000619269(transcript)|ensembl:ENST00000674102(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|rcsb pdb:5YBJ|rcsb pdb:5YBU|reactome:R-HSA-9018519|reactome:R-HSA-9673768|ensembl:ENSG00000107104(gene)|refseq:NP_001243805.1|refseq:NP_001243806.1|refseq:XP_016870003.1|refseq:XP_016870004.1|refseq:XP_016870016.1|refseq:XP_016870017.1|refseq:XP_016870018.1|refseq:XP_016870019.1|refseq:NP_694856.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:HIXdg7zEoEpHcC+KwTUjNFSgr5M9606	rogid:+TXNlWTBf1g8b+TpaR9KiM9f+b89606	rigid:xVclB/UK2JIKvH9HSSa+OOq2H5w	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y6D6	uniprotkb:Q9Y6D5	intact:EBI-1044254|uniprotkb:Q9NV46|uniprotkb:Q9UFV2|uniprotkb:Q9UNL0|ensembl:ENSP00000262215	intact:EBI-2837511|uniprotkb:Q9NTS1|uniprotkb:Q5TFT9|ensembl:ENSP00000360985	psi-mi:big1_human(display_long)|uniprotkb:ARFGEF1(gene name)|psi-mi:ARFGEF1(display_short)|uniprotkb:ARFGEP1(gene name synonym)|uniprotkb:BIG1(gene name synonym)|uniprotkb:p200 ARF-GEP1(gene name synonym)|uniprotkb:p200 ARF guanine nucleotide exchange factor(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 1(gene name synonym)	psi-mi:big2_human(display_long)|uniprotkb:ARFGEF2(gene name)|psi-mi:ARFGEF2(display_short)|uniprotkb:ARFGEP2(gene name synonym)|uniprotkb:BIG2(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:22084092|doi:10.1073/pnas.1117011108|imex:IM-17951	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953606|imex:IM-17951-3|dip:DIP-189476E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000066777(gene)|ensembl:ENST00000262215(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007030"(Golgi organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017022"(myosin binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090284"(positive regulation of protein glycosylation in Golgi)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|mint:Q9Y6D6|rcsb pdb:3LTL|rcsb pdb:5EE5|rcsb pdb:5J5C|go:"GO:0051897"(positive regulation of protein kinase B signaling)|refseq:NP_006412.2|refseq:XP_005251191.1|dip:DIP-29748N	refseq:NP_006411.2|ensembl:ENSG00000124198(gene)|ensembl:ENST00000371917(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001881"(receptor recycling)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032280"(symmetric synapse)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0055037"(recycling endosome)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rcsb pdb:3L8N|rcsb pdb:3SWV|reactome:R-HSA-390471|go:"GO:0005794"(Golgi apparatus)|dip:DIP-48794N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:HIXdg7zEoEpHcC+KwTUjNFSgr5M9606	rogid:y64XGrD2XxX6vTmWOW0hbjDzDCk9606	rigid:xVclB/UK2JIKvH9HSSa+OOq2H5w	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14678	uniprotkb:Q9Y6D6	intact:EBI-2556221|uniprotkb:Q8IY65|uniprotkb:Q8WX74|uniprotkb:Q5W0W0|uniprotkb:D3DRH3|ensembl:ENSP00000501167|ensembl:ENSP00000371734|ensembl:ENSP00000371740|ensembl:ENSP00000477725|uniprotkb:A2A2W8	intact:EBI-1044254|uniprotkb:Q9NV46|uniprotkb:Q9UFV2|uniprotkb:Q9UNL0|ensembl:ENSP00000262215	psi-mi:kank1_human(display_long)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)	psi-mi:big1_human(display_long)|uniprotkb:ARFGEF1(gene name)|psi-mi:ARFGEF1(display_short)|uniprotkb:ARFGEP1(gene name synonym)|uniprotkb:BIG1(gene name synonym)|uniprotkb:p200 ARF-GEP1(gene name synonym)|uniprotkb:p200 ARF guanine nucleotide exchange factor(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:22084092|doi:10.1073/pnas.1117011108|imex:IM-17951	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953625|imex:IM-17951-4|dip:DIP-189478E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-56491N|refseq:NP_055973.2|ensembl:ENST00000382297(transcript)|ensembl:ENST00000382303(transcript)|ensembl:ENST00000619269(transcript)|ensembl:ENST00000674102(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|rcsb pdb:5YBJ|rcsb pdb:5YBU|reactome:R-HSA-9018519|reactome:R-HSA-9673768|ensembl:ENSG00000107104(gene)|refseq:NP_001243805.1|refseq:NP_001243806.1|refseq:XP_016870003.1|refseq:XP_016870004.1|refseq:XP_016870016.1|refseq:XP_016870017.1|refseq:XP_016870018.1|refseq:XP_016870019.1|refseq:NP_694856.1	ensembl:ENSG00000066777(gene)|ensembl:ENST00000262215(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007030"(Golgi organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017022"(myosin binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090284"(positive regulation of protein glycosylation in Golgi)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|mint:Q9Y6D6|rcsb pdb:3LTL|rcsb pdb:5EE5|rcsb pdb:5J5C|go:"GO:0051897"(positive regulation of protein kinase B signaling)|refseq:NP_006412.2|refseq:XP_005251191.1|dip:DIP-29748N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:+TXNlWTBf1g8b+TpaR9KiM9f+b89606	rogid:HIXdg7zEoEpHcC+KwTUjNFSgr5M9606	rigid:LO92MZLDBCjR6mq9dURy81HvltI	false	myc tag:c-c	sufficient binding region:1-885|sufficient binding region:886-1849|ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9Y6D6	uniprotkb:Q7Z4S6	intact:EBI-1044254|uniprotkb:Q9NV46|uniprotkb:Q9UFV2|uniprotkb:Q9UNL0|ensembl:ENSP00000262215	intact:EBI-2691397|intact:EBI-11051686|uniprotkb:Q9C0F5|uniprotkb:Q9Y590|uniprotkb:Q86WZ5|uniprotkb:Q8IVZ8|uniprotkb:Q9NXU4|uniprotkb:B0I1R9|uniprotkb:A8MX28|uniprotkb:Q7Z668|uniprotkb:Q6UKL9|uniprotkb:B9EGE4|uniprotkb:F5H0C3|uniprotkb:F5H219|uniprotkb:Q2UVF1|intact:EBI-28975118|ensembl:ENSP00000354878	psi-mi:big1_human(display_long)|uniprotkb:ARFGEF1(gene name)|psi-mi:ARFGEF1(display_short)|uniprotkb:ARFGEP1(gene name synonym)|uniprotkb:BIG1(gene name synonym)|uniprotkb:p200 ARF-GEP1(gene name synonym)|uniprotkb:p200 ARF guanine nucleotide exchange factor(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 1(gene name synonym)	psi-mi:ki21a_human(display_long)|uniprotkb:KIAA1708(gene name synonym)|uniprotkb:KIF2(gene name synonym)|uniprotkb:Kinesin-like protein KIF2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-62(gene name synonym)|uniprotkb:KIF21A(gene name)|psi-mi:KIF21A(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:22084092|doi:10.1073/pnas.1117011108|imex:IM-17951	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953588|imex:IM-17951-2|dip:DIP-189477E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000066777(gene)|ensembl:ENST00000262215(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007030"(Golgi organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017022"(myosin binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090284"(positive regulation of protein glycosylation in Golgi)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|mint:Q9Y6D6|rcsb pdb:3LTL|rcsb pdb:5EE5|rcsb pdb:5J5C|go:"GO:0051897"(positive regulation of protein kinase B signaling)|refseq:NP_006412.2|refseq:XP_005251191.1|dip:DIP-29748N	ensembl:ENSP00000354878|ensembl:ENST00000361961|ensembl:ENSP00000354851|ensembl:ENST00000541463|ensembl:ENSP00000438075|ensembl:ENST00000544797|ensembl:ENSP00000445606|refseq:NP_001166934.1|refseq:NP_001166935.1|refseq:NP_001166936.1|refseq:NP_060111.2|refseq:XP_005269064.1|refseq:XP_005269070.1|ensembl:ENSG00000139116(gene)|ensembl:ENST00000361418(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:1990939"|interpro:IPR001680(WD40 repeat)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036322|interpro:IPR036961|rcsb pdb:5D3A|rcsb pdb:5NFD|rcsb pdb:5YBU|rcsb pdb:5YBV|rcsb pdb:7KLJ|reactome:R-HSA-6811434|reactome:R-HSA-983189|dip:DIP-56253N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:HIXdg7zEoEpHcC+KwTUjNFSgr5M9606	rogid:GRF+n9Srey50s4v6s2Z2E23/x0s9606	rigid:lgqeVVdrX03yWD1JvesPzJOeXEg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y6D6	uniprotkb:Q14678	intact:EBI-1044254|uniprotkb:Q9NV46|uniprotkb:Q9UFV2|uniprotkb:Q9UNL0|ensembl:ENSP00000262215	intact:EBI-2556221|uniprotkb:Q8IY65|uniprotkb:Q8WX74|uniprotkb:Q5W0W0|uniprotkb:D3DRH3|ensembl:ENSP00000501167|ensembl:ENSP00000371734|ensembl:ENSP00000371740|ensembl:ENSP00000477725|uniprotkb:A2A2W8	psi-mi:big1_human(display_long)|uniprotkb:ARFGEF1(gene name)|psi-mi:ARFGEF1(display_short)|uniprotkb:ARFGEP1(gene name synonym)|uniprotkb:BIG1(gene name synonym)|uniprotkb:p200 ARF-GEP1(gene name synonym)|uniprotkb:p200 ARF guanine nucleotide exchange factor(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 1(gene name synonym)	psi-mi:kank1_human(display_long)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:22084092|doi:10.1073/pnas.1117011108|imex:IM-17951	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953588|imex:IM-17951-2|dip:DIP-189477E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000066777(gene)|ensembl:ENST00000262215(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007030"(Golgi organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017022"(myosin binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090284"(positive regulation of protein glycosylation in Golgi)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|mint:Q9Y6D6|rcsb pdb:3LTL|rcsb pdb:5EE5|rcsb pdb:5J5C|go:"GO:0051897"(positive regulation of protein kinase B signaling)|refseq:NP_006412.2|refseq:XP_005251191.1|dip:DIP-29748N	dip:DIP-56491N|refseq:NP_055973.2|ensembl:ENST00000382297(transcript)|ensembl:ENST00000382303(transcript)|ensembl:ENST00000619269(transcript)|ensembl:ENST00000674102(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|rcsb pdb:5YBJ|rcsb pdb:5YBU|reactome:R-HSA-9018519|reactome:R-HSA-9673768|ensembl:ENSG00000107104(gene)|refseq:NP_001243805.1|refseq:NP_001243806.1|refseq:XP_016870003.1|refseq:XP_016870004.1|refseq:XP_016870016.1|refseq:XP_016870017.1|refseq:XP_016870018.1|refseq:XP_016870019.1|refseq:NP_694856.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:HIXdg7zEoEpHcC+KwTUjNFSgr5M9606	rogid:+TXNlWTBf1g8b+TpaR9KiM9f+b89606	rigid:lgqeVVdrX03yWD1JvesPzJOeXEg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q7Z4S6	uniprotkb:Q9Y6D6	intact:EBI-2691397|intact:EBI-11051686|uniprotkb:Q9C0F5|uniprotkb:Q9Y590|uniprotkb:Q86WZ5|uniprotkb:Q8IVZ8|uniprotkb:Q9NXU4|uniprotkb:B0I1R9|uniprotkb:A8MX28|uniprotkb:Q7Z668|uniprotkb:Q6UKL9|uniprotkb:B9EGE4|uniprotkb:F5H0C3|uniprotkb:F5H219|uniprotkb:Q2UVF1|intact:EBI-28975118|ensembl:ENSP00000354878	intact:EBI-1044254|uniprotkb:Q9NV46|uniprotkb:Q9UFV2|uniprotkb:Q9UNL0|ensembl:ENSP00000262215	psi-mi:ki21a_human(display_long)|uniprotkb:KIAA1708(gene name synonym)|uniprotkb:KIF2(gene name synonym)|uniprotkb:Kinesin-like protein KIF2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-62(gene name synonym)|uniprotkb:KIF21A(gene name)|psi-mi:KIF21A(display_short)	psi-mi:big1_human(display_long)|uniprotkb:ARFGEF1(gene name)|psi-mi:ARFGEF1(display_short)|uniprotkb:ARFGEP1(gene name synonym)|uniprotkb:BIG1(gene name synonym)|uniprotkb:p200 ARF-GEP1(gene name synonym)|uniprotkb:p200 ARF guanine nucleotide exchange factor(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:22084092|doi:10.1073/pnas.1117011108|imex:IM-17951	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953650|imex:IM-17951-5|dip:DIP-189479E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000354878|ensembl:ENST00000361961|ensembl:ENSP00000354851|ensembl:ENST00000541463|ensembl:ENSP00000438075|ensembl:ENST00000544797|ensembl:ENSP00000445606|refseq:NP_001166934.1|refseq:NP_001166935.1|refseq:NP_001166936.1|refseq:NP_060111.2|refseq:XP_005269064.1|refseq:XP_005269070.1|ensembl:ENSG00000139116(gene)|ensembl:ENST00000361418(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:1990939"|interpro:IPR001680(WD40 repeat)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036322|interpro:IPR036961|rcsb pdb:5D3A|rcsb pdb:5NFD|rcsb pdb:5YBU|rcsb pdb:5YBV|rcsb pdb:7KLJ|reactome:R-HSA-6811434|reactome:R-HSA-983189|dip:DIP-56253N	ensembl:ENSG00000066777(gene)|ensembl:ENST00000262215(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007030"(Golgi organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017022"(myosin binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090284"(positive regulation of protein glycosylation in Golgi)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|mint:Q9Y6D6|rcsb pdb:3LTL|rcsb pdb:5EE5|rcsb pdb:5J5C|go:"GO:0051897"(positive regulation of protein kinase B signaling)|refseq:NP_006412.2|refseq:XP_005251191.1|dip:DIP-29748N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:GRF+n9Srey50s4v6s2Z2E23/x0s9606	rogid:HIXdg7zEoEpHcC+KwTUjNFSgr5M9606	rigid:JBEPYE0Jb2N/rW6tnplYvRITvkM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14678	uniprotkb:Q9Y6D6	intact:EBI-2556221|uniprotkb:Q8IY65|uniprotkb:Q8WX74|uniprotkb:Q5W0W0|uniprotkb:D3DRH3|ensembl:ENSP00000501167|ensembl:ENSP00000371734|ensembl:ENSP00000371740|ensembl:ENSP00000477725|uniprotkb:A2A2W8	intact:EBI-1044254|uniprotkb:Q9NV46|uniprotkb:Q9UFV2|uniprotkb:Q9UNL0|ensembl:ENSP00000262215	psi-mi:kank1_human(display_long)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)	psi-mi:big1_human(display_long)|uniprotkb:ARFGEF1(gene name)|psi-mi:ARFGEF1(display_short)|uniprotkb:ARFGEP1(gene name synonym)|uniprotkb:BIG1(gene name synonym)|uniprotkb:p200 ARF-GEP1(gene name synonym)|uniprotkb:p200 ARF guanine nucleotide exchange factor(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:22084092|doi:10.1073/pnas.1117011108|imex:IM-17951	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953667|imex:IM-17951-6|dip:DIP-189478E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-56491N|refseq:NP_055973.2|ensembl:ENST00000382297(transcript)|ensembl:ENST00000382303(transcript)|ensembl:ENST00000619269(transcript)|ensembl:ENST00000674102(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|rcsb pdb:5YBJ|rcsb pdb:5YBU|reactome:R-HSA-9018519|reactome:R-HSA-9673768|ensembl:ENSG00000107104(gene)|refseq:NP_001243805.1|refseq:NP_001243806.1|refseq:XP_016870003.1|refseq:XP_016870004.1|refseq:XP_016870016.1|refseq:XP_016870017.1|refseq:XP_016870018.1|refseq:XP_016870019.1|refseq:NP_694856.1	ensembl:ENSG00000066777(gene)|ensembl:ENST00000262215(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007030"(Golgi organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017022"(myosin binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090284"(positive regulation of protein glycosylation in Golgi)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|mint:Q9Y6D6|rcsb pdb:3LTL|rcsb pdb:5EE5|rcsb pdb:5J5C|go:"GO:0051897"(positive regulation of protein kinase B signaling)|refseq:NP_006412.2|refseq:XP_005251191.1|dip:DIP-29748N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:+TXNlWTBf1g8b+TpaR9KiM9f+b89606	rogid:HIXdg7zEoEpHcC+KwTUjNFSgr5M9606	rigid:LO92MZLDBCjR6mq9dURy81HvltI	false	myc tag:c-c	sufficient binding region:1-885|sufficient binding region:886-1849|ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q14678	uniprotkb:Q9Y6D6	intact:EBI-2556221|uniprotkb:Q8IY65|uniprotkb:Q8WX74|uniprotkb:Q5W0W0|uniprotkb:D3DRH3|ensembl:ENSP00000501167|ensembl:ENSP00000371734|ensembl:ENSP00000371740|ensembl:ENSP00000477725|uniprotkb:A2A2W8	intact:EBI-1044254|uniprotkb:Q9NV46|uniprotkb:Q9UFV2|uniprotkb:Q9UNL0|ensembl:ENSP00000262215	psi-mi:kank1_human(display_long)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)	psi-mi:big1_human(display_long)|uniprotkb:ARFGEF1(gene name)|psi-mi:ARFGEF1(display_short)|uniprotkb:ARFGEP1(gene name synonym)|uniprotkb:BIG1(gene name synonym)|uniprotkb:p200 ARF-GEP1(gene name synonym)|uniprotkb:p200 ARF guanine nucleotide exchange factor(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:22084092|doi:10.1073/pnas.1117011108|imex:IM-17951	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953692|imex:IM-17951-7|dip:DIP-189478E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-56491N|refseq:NP_055973.2|ensembl:ENST00000382297(transcript)|ensembl:ENST00000382303(transcript)|ensembl:ENST00000619269(transcript)|ensembl:ENST00000674102(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|rcsb pdb:5YBJ|rcsb pdb:5YBU|reactome:R-HSA-9018519|reactome:R-HSA-9673768|ensembl:ENSG00000107104(gene)|refseq:NP_001243805.1|refseq:NP_001243806.1|refseq:XP_016870003.1|refseq:XP_016870004.1|refseq:XP_016870016.1|refseq:XP_016870017.1|refseq:XP_016870018.1|refseq:XP_016870019.1|refseq:NP_694856.1	ensembl:ENSG00000066777(gene)|ensembl:ENST00000262215(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007030"(Golgi organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017022"(myosin binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090284"(positive regulation of protein glycosylation in Golgi)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|mint:Q9Y6D6|rcsb pdb:3LTL|rcsb pdb:5EE5|rcsb pdb:5J5C|go:"GO:0051897"(positive regulation of protein kinase B signaling)|refseq:NP_006412.2|refseq:XP_005251191.1|dip:DIP-29748N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:+TXNlWTBf1g8b+TpaR9KiM9f+b89606	rogid:HIXdg7zEoEpHcC+KwTUjNFSgr5M9606	rigid:LO92MZLDBCjR6mq9dURy81HvltI	false	myc tag:c-c	sufficient binding region:1-885|sufficient binding region:886-1849|ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q7Z4S6	uniprotkb:Q14678	intact:EBI-2691397|intact:EBI-11051686|uniprotkb:Q9C0F5|uniprotkb:Q9Y590|uniprotkb:Q86WZ5|uniprotkb:Q8IVZ8|uniprotkb:Q9NXU4|uniprotkb:B0I1R9|uniprotkb:A8MX28|uniprotkb:Q7Z668|uniprotkb:Q6UKL9|uniprotkb:B9EGE4|uniprotkb:F5H0C3|uniprotkb:F5H219|uniprotkb:Q2UVF1|intact:EBI-28975118|ensembl:ENSP00000354878	intact:EBI-2556221|uniprotkb:Q8IY65|uniprotkb:Q8WX74|uniprotkb:Q5W0W0|uniprotkb:D3DRH3|ensembl:ENSP00000501167|ensembl:ENSP00000371734|ensembl:ENSP00000371740|ensembl:ENSP00000477725|uniprotkb:A2A2W8	psi-mi:ki21a_human(display_long)|uniprotkb:KIAA1708(gene name synonym)|uniprotkb:KIF2(gene name synonym)|uniprotkb:Kinesin-like protein KIF2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-62(gene name synonym)|uniprotkb:KIF21A(gene name)|psi-mi:KIF21A(display_short)	psi-mi:kank1_human(display_long)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:22084092|doi:10.1073/pnas.1117011108|imex:IM-17951	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953717|imex:IM-17951-8|dip:DIP-189477E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000354878|ensembl:ENST00000361961|ensembl:ENSP00000354851|ensembl:ENST00000541463|ensembl:ENSP00000438075|ensembl:ENST00000544797|ensembl:ENSP00000445606|refseq:NP_001166934.1|refseq:NP_001166935.1|refseq:NP_001166936.1|refseq:NP_060111.2|refseq:XP_005269064.1|refseq:XP_005269070.1|ensembl:ENSG00000139116(gene)|ensembl:ENST00000361418(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:1990939"|interpro:IPR001680(WD40 repeat)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036322|interpro:IPR036961|rcsb pdb:5D3A|rcsb pdb:5NFD|rcsb pdb:5YBU|rcsb pdb:5YBV|rcsb pdb:7KLJ|reactome:R-HSA-6811434|reactome:R-HSA-983189|dip:DIP-56253N	dip:DIP-56491N|refseq:NP_055973.2|ensembl:ENST00000382297(transcript)|ensembl:ENST00000382303(transcript)|ensembl:ENST00000619269(transcript)|ensembl:ENST00000674102(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|rcsb pdb:5YBJ|rcsb pdb:5YBU|reactome:R-HSA-9018519|reactome:R-HSA-9673768|ensembl:ENSG00000107104(gene)|refseq:NP_001243805.1|refseq:NP_001243806.1|refseq:XP_016870003.1|refseq:XP_016870004.1|refseq:XP_016870016.1|refseq:XP_016870017.1|refseq:XP_016870018.1|refseq:XP_016870019.1|refseq:NP_694856.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:GRF+n9Srey50s4v6s2Z2E23/x0s9606	rogid:+TXNlWTBf1g8b+TpaR9KiM9f+b89606	rigid:lgqeVVdrX03yWD1JvesPzJOeXEg	false	ha tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q7Z4S6	uniprotkb:Q9Y6D6	intact:EBI-2691397|intact:EBI-11051686|uniprotkb:Q9C0F5|uniprotkb:Q9Y590|uniprotkb:Q86WZ5|uniprotkb:Q8IVZ8|uniprotkb:Q9NXU4|uniprotkb:B0I1R9|uniprotkb:A8MX28|uniprotkb:Q7Z668|uniprotkb:Q6UKL9|uniprotkb:B9EGE4|uniprotkb:F5H0C3|uniprotkb:F5H219|uniprotkb:Q2UVF1|intact:EBI-28975118|ensembl:ENSP00000354878	intact:EBI-1044254|uniprotkb:Q9NV46|uniprotkb:Q9UFV2|uniprotkb:Q9UNL0|ensembl:ENSP00000262215	psi-mi:ki21a_human(display_long)|uniprotkb:KIAA1708(gene name synonym)|uniprotkb:KIF2(gene name synonym)|uniprotkb:Kinesin-like protein KIF2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-62(gene name synonym)|uniprotkb:KIF21A(gene name)|psi-mi:KIF21A(display_short)	psi-mi:big1_human(display_long)|uniprotkb:ARFGEF1(gene name)|psi-mi:ARFGEF1(display_short)|uniprotkb:ARFGEP1(gene name synonym)|uniprotkb:BIG1(gene name synonym)|uniprotkb:p200 ARF-GEP1(gene name synonym)|uniprotkb:p200 ARF guanine nucleotide exchange factor(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:22084092|doi:10.1073/pnas.1117011108|imex:IM-17951	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953717|imex:IM-17951-8|dip:DIP-189477E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000354878|ensembl:ENST00000361961|ensembl:ENSP00000354851|ensembl:ENST00000541463|ensembl:ENSP00000438075|ensembl:ENST00000544797|ensembl:ENSP00000445606|refseq:NP_001166934.1|refseq:NP_001166935.1|refseq:NP_001166936.1|refseq:NP_060111.2|refseq:XP_005269064.1|refseq:XP_005269070.1|ensembl:ENSG00000139116(gene)|ensembl:ENST00000361418(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:1990939"|interpro:IPR001680(WD40 repeat)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036322|interpro:IPR036961|rcsb pdb:5D3A|rcsb pdb:5NFD|rcsb pdb:5YBU|rcsb pdb:5YBV|rcsb pdb:7KLJ|reactome:R-HSA-6811434|reactome:R-HSA-983189|dip:DIP-56253N	ensembl:ENSG00000066777(gene)|ensembl:ENST00000262215(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007030"(Golgi organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017022"(myosin binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090284"(positive regulation of protein glycosylation in Golgi)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|mint:Q9Y6D6|rcsb pdb:3LTL|rcsb pdb:5EE5|rcsb pdb:5J5C|go:"GO:0051897"(positive regulation of protein kinase B signaling)|refseq:NP_006412.2|refseq:XP_005251191.1|dip:DIP-29748N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:GRF+n9Srey50s4v6s2Z2E23/x0s9606	rogid:HIXdg7zEoEpHcC+KwTUjNFSgr5M9606	rigid:lgqeVVdrX03yWD1JvesPzJOeXEg	false	ha tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q14678	uniprotkb:Q9Y6D6	intact:EBI-2556221|uniprotkb:Q8IY65|uniprotkb:Q8WX74|uniprotkb:Q5W0W0|uniprotkb:D3DRH3|ensembl:ENSP00000501167|ensembl:ENSP00000371734|ensembl:ENSP00000371740|ensembl:ENSP00000477725|uniprotkb:A2A2W8	intact:EBI-1044254|uniprotkb:Q9NV46|uniprotkb:Q9UFV2|uniprotkb:Q9UNL0|ensembl:ENSP00000262215	psi-mi:kank1_human(display_long)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)	psi-mi:big1_human(display_long)|uniprotkb:ARFGEF1(gene name)|psi-mi:ARFGEF1(display_short)|uniprotkb:ARFGEP1(gene name synonym)|uniprotkb:BIG1(gene name synonym)|uniprotkb:p200 ARF-GEP1(gene name synonym)|uniprotkb:p200 ARF guanine nucleotide exchange factor(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:22084092|doi:10.1073/pnas.1117011108|imex:IM-17951	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953737|imex:IM-17951-9|dip:DIP-189478E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-56491N|refseq:NP_055973.2|ensembl:ENST00000382297(transcript)|ensembl:ENST00000382303(transcript)|ensembl:ENST00000619269(transcript)|ensembl:ENST00000674102(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|rcsb pdb:5YBJ|rcsb pdb:5YBU|reactome:R-HSA-9018519|reactome:R-HSA-9673768|ensembl:ENSG00000107104(gene)|refseq:NP_001243805.1|refseq:NP_001243806.1|refseq:XP_016870003.1|refseq:XP_016870004.1|refseq:XP_016870016.1|refseq:XP_016870017.1|refseq:XP_016870018.1|refseq:XP_016870019.1|refseq:NP_694856.1	ensembl:ENSG00000066777(gene)|ensembl:ENST00000262215(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007030"(Golgi organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017022"(myosin binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090284"(positive regulation of protein glycosylation in Golgi)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|mint:Q9Y6D6|rcsb pdb:3LTL|rcsb pdb:5EE5|rcsb pdb:5J5C|go:"GO:0051897"(positive regulation of protein kinase B signaling)|refseq:NP_006412.2|refseq:XP_005251191.1|dip:DIP-29748N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:+TXNlWTBf1g8b+TpaR9KiM9f+b89606	rogid:HIXdg7zEoEpHcC+KwTUjNFSgr5M9606	rigid:LO92MZLDBCjR6mq9dURy81HvltI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y6D5	uniprotkb:Q9Y6D6	intact:EBI-2837511|uniprotkb:Q9NTS1|uniprotkb:Q5TFT9|ensembl:ENSP00000360985	intact:EBI-1044254|uniprotkb:Q9NV46|uniprotkb:Q9UFV2|uniprotkb:Q9UNL0|ensembl:ENSP00000262215	psi-mi:big2_human(display_long)|uniprotkb:ARFGEF2(gene name)|psi-mi:ARFGEF2(display_short)|uniprotkb:ARFGEP2(gene name synonym)|uniprotkb:BIG2(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 2(gene name synonym)	psi-mi:big1_human(display_long)|uniprotkb:ARFGEF1(gene name)|psi-mi:ARFGEF1(display_short)|uniprotkb:ARFGEP1(gene name synonym)|uniprotkb:BIG1(gene name synonym)|uniprotkb:p200 ARF-GEP1(gene name synonym)|uniprotkb:p200 ARF guanine nucleotide exchange factor(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:22084092|doi:10.1073/pnas.1117011108|imex:IM-17951	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953754|imex:IM-17951-10|dip:DIP-103739E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006411.2|ensembl:ENSG00000124198(gene)|ensembl:ENST00000371917(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001881"(receptor recycling)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032280"(symmetric synapse)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0055037"(recycling endosome)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rcsb pdb:3L8N|rcsb pdb:3SWV|reactome:R-HSA-390471|go:"GO:0005794"(Golgi apparatus)|dip:DIP-48794N	ensembl:ENSG00000066777(gene)|ensembl:ENST00000262215(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007030"(Golgi organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017022"(myosin binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090284"(positive regulation of protein glycosylation in Golgi)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|mint:Q9Y6D6|rcsb pdb:3LTL|rcsb pdb:5EE5|rcsb pdb:5J5C|go:"GO:0051897"(positive regulation of protein kinase B signaling)|refseq:NP_006412.2|refseq:XP_005251191.1|dip:DIP-29748N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:y64XGrD2XxX6vTmWOW0hbjDzDCk9606	rogid:HIXdg7zEoEpHcC+KwTUjNFSgr5M9606	rigid:K1FIjQKCVF8E68Uz7NJll3pI7Ps	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14678	uniprotkb:Q9Y6D6	intact:EBI-2556221|uniprotkb:Q8IY65|uniprotkb:Q8WX74|uniprotkb:Q5W0W0|uniprotkb:D3DRH3|ensembl:ENSP00000501167|ensembl:ENSP00000371734|ensembl:ENSP00000371740|ensembl:ENSP00000477725|uniprotkb:A2A2W8	intact:EBI-1044254|uniprotkb:Q9NV46|uniprotkb:Q9UFV2|uniprotkb:Q9UNL0|ensembl:ENSP00000262215	psi-mi:kank1_human(display_long)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)	psi-mi:big1_human(display_long)|uniprotkb:ARFGEF1(gene name)|psi-mi:ARFGEF1(display_short)|uniprotkb:ARFGEP1(gene name synonym)|uniprotkb:BIG1(gene name synonym)|uniprotkb:p200 ARF-GEP1(gene name synonym)|uniprotkb:p200 ARF guanine nucleotide exchange factor(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:22084092|doi:10.1073/pnas.1117011108|imex:IM-17951	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953771|imex:IM-17951-11|dip:DIP-189478E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-56491N|refseq:NP_055973.2|ensembl:ENST00000382297(transcript)|ensembl:ENST00000382303(transcript)|ensembl:ENST00000619269(transcript)|ensembl:ENST00000674102(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|rcsb pdb:5YBJ|rcsb pdb:5YBU|reactome:R-HSA-9018519|reactome:R-HSA-9673768|ensembl:ENSG00000107104(gene)|refseq:NP_001243805.1|refseq:NP_001243806.1|refseq:XP_016870003.1|refseq:XP_016870004.1|refseq:XP_016870016.1|refseq:XP_016870017.1|refseq:XP_016870018.1|refseq:XP_016870019.1|refseq:NP_694856.1	ensembl:ENSG00000066777(gene)|ensembl:ENST00000262215(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007030"(Golgi organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017022"(myosin binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090284"(positive regulation of protein glycosylation in Golgi)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|mint:Q9Y6D6|rcsb pdb:3LTL|rcsb pdb:5EE5|rcsb pdb:5J5C|go:"GO:0051897"(positive regulation of protein kinase B signaling)|refseq:NP_006412.2|refseq:XP_005251191.1|dip:DIP-29748N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:+TXNlWTBf1g8b+TpaR9KiM9f+b89606	rogid:HIXdg7zEoEpHcC+KwTUjNFSgr5M9606	rigid:LO92MZLDBCjR6mq9dURy81HvltI	false	myc tag:c-c	sufficient binding region:1-885|sufficient binding region:886-1849|ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)