#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q12860 uniprotkb:P23471 intact:EBI-5564336|uniprotkb:A8K0H9|uniprotkb:A8K0Y3|uniprotkb:Q12861|uniprotkb:Q14030|uniprotkb:Q7M4P0|uniprotkb:Q8N466|ensembl:ENSP00000325660|ensembl:ENSP00000447006 intact:EBI-2263175|uniprotkb:A4D0W5|uniprotkb:O76043|uniprotkb:Q9UDR6|uniprotkb:C9JFM0|ensembl:ENSP00000377047 psi-mi:cntn1_human(display_long)|uniprotkb:CNTN1(gene name)|psi-mi:CNTN1(display_short)|uniprotkb:Glycoprotein gp135(gene name synonym)|uniprotkb:Neural cell surface protein F3(gene name synonym) psi-mi:ptprz_human(display_long)|uniprotkb:PTPRZ1(gene name)|psi-mi:PTPRZ1(display_short)|uniprotkb:HTPZP2(gene name synonym)|uniprotkb:PTPRZ(gene name synonym)|uniprotkb:PTPRZ2(gene name synonym)|uniprotkb:PTPZ(gene name synonym)|uniprotkb:R-PTP-zeta-2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor type Z polypeptide 1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor type Z polypeptide 2(gene name synonym) psi-mi:"MI:0096"(pull down) Lamprianou et al. (2011) pubmed:21969550|doi:10.1073/pnas.1108774108|imex:IM-17784 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15946204|imex:IM-17784-1|dip:DIP-189168E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011536228.1|refseq:XP_011536229.1|refseq:NP_001242992.1|refseq:NP_001242993.1|refseq:NP_001834.2|refseq:NP_778203.1|refseq:XP_005268708.1|refseq:XP_006719304.1|refseq:XP_016874314.1|refseq:XP_016874315.1|refseq:XP_016874316.1|dip:DIP-59714N|ensembl:ENSG00000018236(gene)|ensembl:ENST00000347616(transcript)|ensembl:ENST00000551295(transcript)|go:"GO:0007155"(cell adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0045121"(membrane raft)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099025"(anchored component of postsynaptic membrane)|go:"GO:0099026"(anchored component of presynaptic membrane)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR036992|rcsb pdb:3S97|reactome:R-HSA-2122948|reactome:R-HSA-2979096|reactome:R-HSA-373760|reactome:R-HSA-447043|rcsb pdb:2EE2 refseq:XP_005250576.1|refseq:NP_001193767.1|refseq:NP_001193768.1|refseq:NP_002842.2|dip:DIP-42063N|ensembl:ENSG00000106278(gene)|ensembl:ENST00000393386(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:0072534"(perineuronal net)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036398|interpro:IPR041887|rcsb pdb:3JXF|rcsb pdb:3S97|rcsb pdb:5AWX|rcsb pdb:5H08|reactome:R-HSA-449836 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:wkqpI3hRQ1Y/Q6JeasMbZYYIWWY9606 rogid:iOG4w3mPNa50dCrP0V4V5r1TaSM9606 rigid:sapuIKmgoD44goX2eJxsMA2Vcvs false - sufficient binding region:1-415|fc-igg tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12860 uniprotkb:P23471 intact:EBI-5564336|uniprotkb:A8K0H9|uniprotkb:A8K0Y3|uniprotkb:Q12861|uniprotkb:Q14030|uniprotkb:Q7M4P0|uniprotkb:Q8N466|ensembl:ENSP00000325660|ensembl:ENSP00000447006 intact:EBI-2263175|uniprotkb:A4D0W5|uniprotkb:O76043|uniprotkb:Q9UDR6|uniprotkb:C9JFM0|ensembl:ENSP00000377047 psi-mi:cntn1_human(display_long)|uniprotkb:CNTN1(gene name)|psi-mi:CNTN1(display_short)|uniprotkb:Glycoprotein gp135(gene name synonym)|uniprotkb:Neural cell surface protein F3(gene name synonym) psi-mi:ptprz_human(display_long)|uniprotkb:PTPRZ1(gene name)|psi-mi:PTPRZ1(display_short)|uniprotkb:HTPZP2(gene name synonym)|uniprotkb:PTPRZ(gene name synonym)|uniprotkb:PTPRZ2(gene name synonym)|uniprotkb:PTPZ(gene name synonym)|uniprotkb:R-PTP-zeta-2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor type Z polypeptide 1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor type Z polypeptide 2(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Lamprianou et al. (2011) pubmed:21969550|doi:10.1073/pnas.1108774108|imex:IM-17784 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15946225|imex:IM-17784-2|dip:DIP-189168E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011536228.1|refseq:XP_011536229.1|refseq:NP_001242992.1|refseq:NP_001242993.1|refseq:NP_001834.2|refseq:NP_778203.1|refseq:XP_005268708.1|refseq:XP_006719304.1|refseq:XP_016874314.1|refseq:XP_016874315.1|refseq:XP_016874316.1|dip:DIP-59714N|ensembl:ENSG00000018236(gene)|ensembl:ENST00000347616(transcript)|ensembl:ENST00000551295(transcript)|go:"GO:0007155"(cell adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0045121"(membrane raft)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099025"(anchored component of postsynaptic membrane)|go:"GO:0099026"(anchored component of presynaptic membrane)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR036992|rcsb pdb:3S97|reactome:R-HSA-2122948|reactome:R-HSA-2979096|reactome:R-HSA-373760|reactome:R-HSA-447043|rcsb pdb:2EE2 refseq:XP_005250576.1|refseq:NP_001193767.1|refseq:NP_001193768.1|refseq:NP_002842.2|dip:DIP-42063N|ensembl:ENSG00000106278(gene)|ensembl:ENST00000393386(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:0072534"(perineuronal net)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036398|interpro:IPR041887|rcsb pdb:3JXF|rcsb pdb:3S97|rcsb pdb:5AWX|rcsb pdb:5H08|reactome:R-HSA-449836 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:wkqpI3hRQ1Y/Q6JeasMbZYYIWWY9606 rogid:iOG4w3mPNa50dCrP0V4V5r1TaSM9606 rigid:sapuIKmgoD44goX2eJxsMA2Vcvs false sufficient binding region:133-329 sufficient binding region:34-302 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62656 uniprotkb:Q12860 intact:EBI-15946246|uniprotkb:Q62621 intact:EBI-5564336|uniprotkb:A8K0H9|uniprotkb:A8K0Y3|uniprotkb:Q12861|uniprotkb:Q14030|uniprotkb:Q7M4P0|uniprotkb:Q8N466|ensembl:ENSP00000325660|ensembl:ENSP00000447006 psi-mi:ptprz_rat(display_long)|uniprotkb:Ptprz1(gene name)|psi-mi:Ptprz1(display_short)|uniprotkb:Ptprz(gene name synonym)|uniprotkb:Ptpz(gene name synonym)|uniprotkb:3F8 chondroitin sulfate proteoglycan(gene name synonym)|uniprotkb:3H1 keratan sulfate proteoglycan(gene name synonym)|uniprotkb:Phosphacan(gene name synonym) psi-mi:cntn1_human(display_long)|uniprotkb:CNTN1(gene name)|psi-mi:CNTN1(display_short)|uniprotkb:Glycoprotein gp135(gene name synonym)|uniprotkb:Neural cell surface protein F3(gene name synonym) psi-mi:"MI:0096"(pull down) Lamprianou et al. (2011) pubmed:21969550|doi:10.1073/pnas.1108774108|imex:IM-17784 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15946311|imex:IM-17784-3|dip:DIP-189170E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031012"(extracellular matrix)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048666"(neuron development)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:0072534"(perineuronal net)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900149"(positive regulation of Schwann cell migration)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:2000171"(negative regulation of dendrite development)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036398|interpro:IPR041887|rcsb pdb:6J6U|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007409"(axonogenesis)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007420"(brain development)|go:"GO:0007611"(learning or memory)|reactome:R-RNO-449836|dip:DIP-59715N|rgd:3455|refseq:NP_001164156.1|refseq:NP_037212.2 refseq:XP_011536228.1|refseq:XP_011536229.1|refseq:NP_001242992.1|refseq:NP_001242993.1|refseq:NP_001834.2|refseq:NP_778203.1|refseq:XP_005268708.1|refseq:XP_006719304.1|refseq:XP_016874314.1|refseq:XP_016874315.1|refseq:XP_016874316.1|dip:DIP-59714N|ensembl:ENSG00000018236(gene)|ensembl:ENST00000347616(transcript)|ensembl:ENST00000551295(transcript)|go:"GO:0007155"(cell adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0045121"(membrane raft)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099025"(anchored component of postsynaptic membrane)|go:"GO:0099026"(anchored component of presynaptic membrane)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR036992|rcsb pdb:3S97|reactome:R-HSA-2122948|reactome:R-HSA-2979096|reactome:R-HSA-373760|reactome:R-HSA-447043|rcsb pdb:2EE2 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:3TVzmp6nmbTISdKdBjrAO58arII10116 rogid:wkqpI3hRQ1Y/Q6JeasMbZYYIWWY9606 rigid:SB4ThdEysCVsokG9/fotKGOjkfQ false - fc-igg tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q63198 uniprotkb:P23471 intact:EBI-2255922|ensembl:ENSRNOP00000006219|ensembl:ENSRNOP00000071355 intact:EBI-2263175|uniprotkb:A4D0W5|uniprotkb:O76043|uniprotkb:Q9UDR6|uniprotkb:C9JFM0|ensembl:ENSP00000377047 psi-mi:cntn1_rat(display_long)|uniprotkb:Cntn1(gene name)|psi-mi:Cntn1(display_short)|uniprotkb:Neural cell surface protein F3(gene name synonym) psi-mi:ptprz_human(display_long)|uniprotkb:PTPRZ1(gene name)|psi-mi:PTPRZ1(display_short)|uniprotkb:HTPZP2(gene name synonym)|uniprotkb:PTPRZ(gene name synonym)|uniprotkb:PTPRZ2(gene name synonym)|uniprotkb:PTPZ(gene name synonym)|uniprotkb:R-PTP-zeta-2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor type Z polypeptide 1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor type Z polypeptide 2(gene name synonym) psi-mi:"MI:0096"(pull down) Lamprianou et al. (2011) pubmed:21969550|doi:10.1073/pnas.1108774108|imex:IM-17784 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15946330|imex:IM-17784-4|dip:DIP-189169E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_017450105.1|rgd:621300|refseq:NP_476459.1|refseq:XP_006242239.1|dip:DIP-53082N|ensembl:ENSRNOG00000004438(gene)|ensembl:ENSRNOT00000006219(transcript)|ensembl:ENSRNOT00000080621(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021549"(cerebellum development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0045121"(membrane raft)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0099025"(anchored component of postsynaptic membrane)|go:"GO:0099026"(anchored component of presynaptic membrane)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR036992|mint:Q63198 refseq:XP_005250576.1|refseq:NP_001193767.1|refseq:NP_001193768.1|refseq:NP_002842.2|dip:DIP-42063N|ensembl:ENSG00000106278(gene)|ensembl:ENST00000393386(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:0072534"(perineuronal net)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036398|interpro:IPR041887|rcsb pdb:3JXF|rcsb pdb:3S97|rcsb pdb:5AWX|rcsb pdb:5H08|reactome:R-HSA-449836 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:xwArPbuIT63LL9S/vyET64hKfUk10116 rogid:iOG4w3mPNa50dCrP0V4V5r1TaSM9606 rigid:eHFwExtUkv3IUCis0Y70c3N/XAY false - sufficient binding region:1-415|fc-igg tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12860 uniprotkb:P23471 intact:EBI-5564336|uniprotkb:A8K0H9|uniprotkb:A8K0Y3|uniprotkb:Q12861|uniprotkb:Q14030|uniprotkb:Q7M4P0|uniprotkb:Q8N466|ensembl:ENSP00000325660|ensembl:ENSP00000447006 intact:EBI-2263175|uniprotkb:A4D0W5|uniprotkb:O76043|uniprotkb:Q9UDR6|uniprotkb:C9JFM0|ensembl:ENSP00000377047 psi-mi:cntn1_human(display_long)|uniprotkb:CNTN1(gene name)|psi-mi:CNTN1(display_short)|uniprotkb:Glycoprotein gp135(gene name synonym)|uniprotkb:Neural cell surface protein F3(gene name synonym) psi-mi:ptprz_human(display_long)|uniprotkb:PTPRZ1(gene name)|psi-mi:PTPRZ1(display_short)|uniprotkb:HTPZP2(gene name synonym)|uniprotkb:PTPRZ(gene name synonym)|uniprotkb:PTPRZ2(gene name synonym)|uniprotkb:PTPZ(gene name synonym)|uniprotkb:R-PTP-zeta-2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor type Z polypeptide 1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor type Z polypeptide 2(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Lamprianou et al. (2011) pubmed:21969550|doi:10.1073/pnas.1108774108|imex:IM-17784 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15946352|imex:IM-17784-5|dip:DIP-189168E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011536228.1|refseq:XP_011536229.1|refseq:NP_001242992.1|refseq:NP_001242993.1|refseq:NP_001834.2|refseq:NP_778203.1|refseq:XP_005268708.1|refseq:XP_006719304.1|refseq:XP_016874314.1|refseq:XP_016874315.1|refseq:XP_016874316.1|dip:DIP-59714N|ensembl:ENSG00000018236(gene)|ensembl:ENST00000347616(transcript)|ensembl:ENST00000551295(transcript)|go:"GO:0007155"(cell adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0045121"(membrane raft)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099025"(anchored component of postsynaptic membrane)|go:"GO:0099026"(anchored component of presynaptic membrane)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR036992|rcsb pdb:3S97|reactome:R-HSA-2122948|reactome:R-HSA-2979096|reactome:R-HSA-373760|reactome:R-HSA-447043|rcsb pdb:2EE2 refseq:XP_005250576.1|refseq:NP_001193767.1|refseq:NP_001193768.1|refseq:NP_002842.2|dip:DIP-42063N|ensembl:ENSG00000106278(gene)|ensembl:ENST00000393386(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:0072534"(perineuronal net)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036398|interpro:IPR041887|rcsb pdb:3JXF|rcsb pdb:3S97|rcsb pdb:5AWX|rcsb pdb:5H08|reactome:R-HSA-449836 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:wkqpI3hRQ1Y/Q6JeasMbZYYIWWY9606 rogid:iOG4w3mPNa50dCrP0V4V5r1TaSM9606 rigid:sapuIKmgoD44goX2eJxsMA2Vcvs false sufficient binding region:133-329 sufficient binding region:34-302 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:B9EKR1 uniprotkb:Q12860 intact:EBI-15946373|ensembl:ENSMUSP00000088056 intact:EBI-5564336|uniprotkb:A8K0H9|uniprotkb:A8K0Y3|uniprotkb:Q12861|uniprotkb:Q14030|uniprotkb:Q7M4P0|uniprotkb:Q8N466|ensembl:ENSP00000325660|ensembl:ENSP00000447006 psi-mi:ptprz_mouse(display_long)|uniprotkb:Ptprz1(gene name)|psi-mi:Ptprz1(display_short) psi-mi:cntn1_human(display_long)|uniprotkb:CNTN1(gene name)|psi-mi:CNTN1(display_short)|uniprotkb:Glycoprotein gp135(gene name synonym)|uniprotkb:Neural cell surface protein F3(gene name synonym) psi-mi:"MI:0096"(pull down) Lamprianou et al. (2011) pubmed:21969550|doi:10.1073/pnas.1108774108|imex:IM-17784 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15946403|imex:IM-17784-6|dip:DIP-189171E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000090568(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007409"(axonogenesis)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007611"(learning or memory)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017134"(fibroblast growth factor binding)|ensembl:ENSMUSG00000068748(gene)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:0072534"(perineuronal net)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900149"(positive regulation of Schwann cell migration)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:2000171"(negative regulation of dendrite development)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036398|interpro:IPR041887|mint:B9EKR1|reactome:R-MMU-449836|refseq:NP_001074775.1 refseq:XP_011536228.1|refseq:XP_011536229.1|refseq:NP_001242992.1|refseq:NP_001242993.1|refseq:NP_001834.2|refseq:NP_778203.1|refseq:XP_005268708.1|refseq:XP_006719304.1|refseq:XP_016874314.1|refseq:XP_016874315.1|refseq:XP_016874316.1|dip:DIP-59714N|ensembl:ENSG00000018236(gene)|ensembl:ENST00000347616(transcript)|ensembl:ENST00000551295(transcript)|go:"GO:0007155"(cell adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0045121"(membrane raft)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099025"(anchored component of postsynaptic membrane)|go:"GO:0099026"(anchored component of presynaptic membrane)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR036992|rcsb pdb:3S97|reactome:R-HSA-2122948|reactome:R-HSA-2979096|reactome:R-HSA-373760|reactome:R-HSA-447043|rcsb pdb:2EE2 psi-mi:"MI:0465"(dip) crc64:91C5D58F74BA999C - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:77BTIhylf3r1wcOe95cD5NHguRg10090 rogid:wkqpI3hRQ1Y/Q6JeasMbZYYIWWY9606 rigid:4zrkaprK/Y+M8WdEfp0QLNCtwhs false - fc-igg tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)