#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8U019 uniprotkb:Q8TZK2 intact:EBI-9025098|ensemblbacteria:AAL81925 intact:EBI-9025109|ensemblbacteria:AAL82113 psi-mi:secy_pyrfu(display_long)|uniprotkb:secY(gene name)|psi-mi:secY(display_short)|uniprotkb:Protein transport protein SEC61 subunit alpha homolog(gene name synonym)|uniprotkb:PF1801(locus name) psi-mi:sece_pyrfu(display_long)|uniprotkb:secE(gene name)|psi-mi:secE(display_short)|uniprotkb:Protein transport protein Sec61 gamma subunit homolog(gene name synonym)|uniprotkb:PF1989(locus name) psi-mi:"MI:0114"(x-ray crystallography) Egea et al. (2010) pubmed:20855604|doi:10.1073/pnas.1012556107|imex:IM-16491 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15879181|imex:IM-16491-1|dip:DIP-187740E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_011012942.1|dip:DIP-59389N|ensemblbacteria:AAL81925(transcript)|ensemblbacteria:PF1801(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0016021"(integral component of membrane)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR026593|interpro:IPR030659|rcsb pdb:3MP7 refseq:WP_011013133.1|dip:DIP-59388N|ensemblbacteria:AAL82113(transcript)|ensemblbacteria:PF1989(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009306"(protein secretion)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:3MP7 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:s4SZ6eaORX1uBBtxFgjD/kTeWRU186497 rogid:7oJc8cnb/nHaxmhrS0/B0UUtEJk186497 rigid:wmgQQr1GTbmy8SnOefrpcQ13VX0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8U019 uniprotkb:Q8TZH7 intact:EBI-9025098|ensemblbacteria:AAL81925 intact:EBI-15879198|ensemblbacteria:AAL82140 psi-mi:secy_pyrfu(display_long)|uniprotkb:secY(gene name)|psi-mi:secY(display_short)|uniprotkb:Protein transport protein SEC61 subunit alpha homolog(gene name synonym)|uniprotkb:PF1801(locus name) psi-mi:secg_pyrfu(display_long)|uniprotkb:secG(gene name)|psi-mi:secG(display_short)|uniprotkb:Protein transport protein Sec61 subunit beta homolog(gene name synonym)|uniprotkb:PF2016(locus name) psi-mi:"MI:0096"(pull down) Egea et al. (2010) pubmed:20855604|doi:10.1073/pnas.1012556107|imex:IM-16491 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15879234|imex:IM-16491-3|dip:DIP-187741E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_011012942.1|dip:DIP-59389N|ensemblbacteria:AAL81925(transcript)|ensemblbacteria:PF1801(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0016021"(integral component of membrane)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR026593|interpro:IPR030659|rcsb pdb:3MP7 ensemblbacteria:AAL82140(transcript)|ensemblbacteria:PF2016(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR023531|refseq:WP_011013161.1|dip:DIP-59390N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:s4SZ6eaORX1uBBtxFgjD/kTeWRU186497 rogid:qj6r3k3Fs5rPWSP0Flz1EX694xc186497 rigid:yjzEse6UST7G1M6Nagz4SiU93mU false his tag:c-c - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8U019 uniprotkb:Q8TZK2 intact:EBI-9025098|ensemblbacteria:AAL81925 intact:EBI-9025109|ensemblbacteria:AAL82113 psi-mi:secy_pyrfu(display_long)|uniprotkb:secY(gene name)|psi-mi:secY(display_short)|uniprotkb:Protein transport protein SEC61 subunit alpha homolog(gene name synonym)|uniprotkb:PF1801(locus name) psi-mi:sece_pyrfu(display_long)|uniprotkb:secE(gene name)|psi-mi:secE(display_short)|uniprotkb:Protein transport protein Sec61 gamma subunit homolog(gene name synonym)|uniprotkb:PF1989(locus name) psi-mi:"MI:0096"(pull down) Egea et al. (2010) pubmed:20855604|doi:10.1073/pnas.1012556107|imex:IM-16491 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15879234|imex:IM-16491-3|dip:DIP-187741E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_011012942.1|dip:DIP-59389N|ensemblbacteria:AAL81925(transcript)|ensemblbacteria:PF1801(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0016021"(integral component of membrane)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR026593|interpro:IPR030659|rcsb pdb:3MP7 refseq:WP_011013133.1|dip:DIP-59388N|ensemblbacteria:AAL82113(transcript)|ensemblbacteria:PF1989(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009306"(protein secretion)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:3MP7 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:s4SZ6eaORX1uBBtxFgjD/kTeWRU186497 rogid:7oJc8cnb/nHaxmhrS0/B0UUtEJk186497 rigid:yjzEse6UST7G1M6Nagz4SiU93mU false his tag:c-c - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TZK2 uniprotkb:Q8TZH7 intact:EBI-9025109|ensemblbacteria:AAL82113 intact:EBI-15879198|ensemblbacteria:AAL82140 psi-mi:sece_pyrfu(display_long)|uniprotkb:secE(gene name)|psi-mi:secE(display_short)|uniprotkb:Protein transport protein Sec61 gamma subunit homolog(gene name synonym)|uniprotkb:PF1989(locus name) psi-mi:secg_pyrfu(display_long)|uniprotkb:secG(gene name)|psi-mi:secG(display_short)|uniprotkb:Protein transport protein Sec61 subunit beta homolog(gene name synonym)|uniprotkb:PF2016(locus name) psi-mi:"MI:0071"(molecular sieving) Egea et al. (2010) pubmed:20855604|doi:10.1073/pnas.1012556107|imex:IM-16491 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15879254|imex:IM-16491-4|dip:DIP-187741E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_011013133.1|dip:DIP-59388N|ensemblbacteria:AAL82113(transcript)|ensemblbacteria:PF1989(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009306"(protein secretion)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:3MP7 ensemblbacteria:AAL82140(transcript)|ensemblbacteria:PF2016(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR023531|refseq:WP_011013161.1|dip:DIP-59390N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:7oJc8cnb/nHaxmhrS0/B0UUtEJk186497 rogid:qj6r3k3Fs5rPWSP0Flz1EX694xc186497 rigid:yjzEse6UST7G1M6Nagz4SiU93mU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TZK2 uniprotkb:Q8U019 intact:EBI-9025109|ensemblbacteria:AAL82113 intact:EBI-9025098|ensemblbacteria:AAL81925 psi-mi:sece_pyrfu(display_long)|uniprotkb:secE(gene name)|psi-mi:secE(display_short)|uniprotkb:Protein transport protein Sec61 gamma subunit homolog(gene name synonym)|uniprotkb:PF1989(locus name) psi-mi:secy_pyrfu(display_long)|uniprotkb:secY(gene name)|psi-mi:secY(display_short)|uniprotkb:Protein transport protein SEC61 subunit alpha homolog(gene name synonym)|uniprotkb:PF1801(locus name) psi-mi:"MI:0071"(molecular sieving) Egea et al. (2010) pubmed:20855604|doi:10.1073/pnas.1012556107|imex:IM-16491 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15879254|imex:IM-16491-4|dip:DIP-187741E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_011013133.1|dip:DIP-59388N|ensemblbacteria:AAL82113(transcript)|ensemblbacteria:PF1989(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009306"(protein secretion)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:3MP7 refseq:WP_011012942.1|dip:DIP-59389N|ensemblbacteria:AAL81925(transcript)|ensemblbacteria:PF1801(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0016021"(integral component of membrane)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR026593|interpro:IPR030659|rcsb pdb:3MP7 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:7oJc8cnb/nHaxmhrS0/B0UUtEJk186497 rogid:s4SZ6eaORX1uBBtxFgjD/kTeWRU186497 rigid:yjzEse6UST7G1M6Nagz4SiU93mU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0AG96 uniprotkb:P0AGA2 intact:EBI-6404267|ensemblbacteria:AAC76955|ensemblbacteria:BAE77339|uniprotkb:Q2M8R7|uniprotkb:P16920 intact:EBI-761422|uniprotkb:P03844|uniprotkb:Q2M6W5|ensemblbacteria:AAC76325|ensemblbacteria:BAE77991 psi-mi:sece_ecoli(display_long)|uniprotkb:JW3944(locus name)|uniprotkb:b3981(locus name)|uniprotkb:secE(gene name)|psi-mi:secE(display_short)|uniprotkb:prlG(gene name synonym) psi-mi:secy_ecoli(display_long)|uniprotkb:secY(gene name)|psi-mi:secY(display_short)|uniprotkb:prlA(gene name synonym)|uniprotkb:b3300(locus name)|uniprotkb:JW3262(locus name) psi-mi:"MI:0096"(pull down) Egea et al. (2010) pubmed:20855604|doi:10.1073/pnas.1012556107|imex:IM-16491 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15879272|imex:IM-16491-5|dip:DIP-187526E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC76955(transcript)|ensemblbacteria:b3981(gene)|ensemblbacteria:BAE77339(gene)|ensemblbacteria:BAE77339(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR005807(SecE subunit of protein translocation complex)|interpro:IPR038379|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|rcsb pdb:2AKH|rcsb pdb:2AKI|rcsb pdb:3J45|rcsb pdb:3J46|rcsb pdb:4V6M|rcsb pdb:5GAE|rcsb pdb:5MG3|rcsb pdb:5NCO|go:"GO:0006886"(intracellular protein transport)|rcsb pdb:6R7L|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0009306"(protein secretion)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031522"(cell envelope Sec protein transport complex)|go:"GO:0032978"(protein insertion into membrane from inner side)|go:"GO:0043952"(protein transport by the Sec complex)|refseq:WP_001275702.1|refseq:NP_418408.1|dip:DIP-59303N refseq:NP_417759.1|refseq:WP_001118861.1|dip:DIP-59302N|ensemblbacteria:AAC76325(transcript)|ensemblbacteria:b3300(gene)|ensemblbacteria:BAE77991(gene)|ensemblbacteria:BAE77991(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031522"(cell envelope Sec protein transport complex)|go:"GO:0032978"(protein insertion into membrane from inner side)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR002208(SecY protein)|interpro:IPR023201|interpro:IPR026593|interpro:IPR030659|rcsb pdb:2AKH|rcsb pdb:2AKI|rcsb pdb:3J45|rcsb pdb:3J46|rcsb pdb:4V6M|rcsb pdb:5ABB|rcsb pdb:5GAE|rcsb pdb:5MG3|rcsb pdb:5NCO|rcsb pdb:6R7L psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:6fuhtMf4WGR/D92xi4zIqFuzHgs83333 rogid:bkj4LXOWFcRf8+ZfdG8YNQc3Y7g83333 rigid:2yAFdU1J4nV8Esw01X3KRP26eL4 false his tag:?-? sufficient binding region:1-423 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P0AG96 uniprotkb:P0AG99 intact:EBI-6404267|ensemblbacteria:AAC76955|ensemblbacteria:BAE77339|uniprotkb:Q2M8R7|uniprotkb:P16920 intact:EBI-6404248|ensemblbacteria:AAC76207|ensemblbacteria:BAE77219|uniprotkb:Q2M937|uniprotkb:P33582 psi-mi:sece_ecoli(display_long)|uniprotkb:JW3944(locus name)|uniprotkb:b3981(locus name)|uniprotkb:secE(gene name)|psi-mi:secE(display_short)|uniprotkb:prlG(gene name synonym) psi-mi:secg_ecoli(display_long)|uniprotkb:P12(gene name synonym)|uniprotkb:Preprotein translocase band 1 subunit(gene name synonym)|uniprotkb:JW3142(locus name)|uniprotkb:b3175(locus name)|uniprotkb:secG(gene name)|psi-mi:secG(display_short) psi-mi:"MI:0096"(pull down) Egea et al. (2010) pubmed:20855604|doi:10.1073/pnas.1012556107|imex:IM-16491 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15879272|imex:IM-16491-5|dip:DIP-187526E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC76955(transcript)|ensemblbacteria:b3981(gene)|ensemblbacteria:BAE77339(gene)|ensemblbacteria:BAE77339(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR005807(SecE subunit of protein translocation complex)|interpro:IPR038379|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|rcsb pdb:2AKH|rcsb pdb:2AKI|rcsb pdb:3J45|rcsb pdb:3J46|rcsb pdb:4V6M|rcsb pdb:5GAE|rcsb pdb:5MG3|rcsb pdb:5NCO|go:"GO:0006886"(intracellular protein transport)|rcsb pdb:6R7L|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0009306"(protein secretion)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031522"(cell envelope Sec protein transport complex)|go:"GO:0032978"(protein insertion into membrane from inner side)|go:"GO:0043952"(protein transport by the Sec complex)|refseq:WP_001275702.1|refseq:NP_418408.1|dip:DIP-59303N ensemblbacteria:AAC76207(transcript)|ensemblbacteria:b3175(gene)|ensemblbacteria:BAE77219(gene)|ensemblbacteria:BAE77219(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0009306"(protein secretion)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031522"(cell envelope Sec protein transport complex)|go:"GO:0032978"(protein insertion into membrane from inner side)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR004692(Preprotein translocase SecG subunit)|rcsb pdb:2AKH|rcsb pdb:2AKI|rcsb pdb:3J45|rcsb pdb:3J46|rcsb pdb:5MG3|rcsb pdb:5NCO|refseq:WP_001295556.1|mint:P0AG99|refseq:NP_417642.1|dip:DIP-47480N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:6fuhtMf4WGR/D92xi4zIqFuzHgs83333 rogid:7v7uXXyGEOasIRWvJ3w7ABBhLWk83333 rigid:2yAFdU1J4nV8Esw01X3KRP26eL4 false his tag:?-? - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q8TZK2 uniprotkb:Q8TZH7 intact:EBI-9025109|ensemblbacteria:AAL82113 intact:EBI-15879198|ensemblbacteria:AAL82140 psi-mi:sece_pyrfu(display_long)|uniprotkb:secE(gene name)|psi-mi:secE(display_short)|uniprotkb:Protein transport protein Sec61 gamma subunit homolog(gene name synonym)|uniprotkb:PF1989(locus name) psi-mi:secg_pyrfu(display_long)|uniprotkb:secG(gene name)|psi-mi:secG(display_short)|uniprotkb:Protein transport protein Sec61 subunit beta homolog(gene name synonym)|uniprotkb:PF2016(locus name) psi-mi:"MI:0096"(pull down) Egea et al. (2010) pubmed:20855604|doi:10.1073/pnas.1012556107|imex:IM-16491 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15879212|dip:DIP-187741E|imex:IM-16491-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_011013133.1|dip:DIP-59388N|ensemblbacteria:AAL82113(transcript)|ensemblbacteria:PF1989(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009306"(protein secretion)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:3MP7 ensemblbacteria:AAL82140(transcript)|ensemblbacteria:PF2016(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR023531|refseq:WP_011013161.1|dip:DIP-59390N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:7oJc8cnb/nHaxmhrS0/B0UUtEJk186497 rogid:qj6r3k3Fs5rPWSP0Flz1EX694xc186497 rigid:yjzEse6UST7G1M6Nagz4SiU93mU false his tag:?-? - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q8TZK2 uniprotkb:Q8U019 intact:EBI-9025109|ensemblbacteria:AAL82113 intact:EBI-9025098|ensemblbacteria:AAL81925 psi-mi:sece_pyrfu(display_long)|uniprotkb:secE(gene name)|psi-mi:secE(display_short)|uniprotkb:Protein transport protein Sec61 gamma subunit homolog(gene name synonym)|uniprotkb:PF1989(locus name) psi-mi:secy_pyrfu(display_long)|uniprotkb:secY(gene name)|psi-mi:secY(display_short)|uniprotkb:Protein transport protein SEC61 subunit alpha homolog(gene name synonym)|uniprotkb:PF1801(locus name) psi-mi:"MI:0096"(pull down) Egea et al. (2010) pubmed:20855604|doi:10.1073/pnas.1012556107|imex:IM-16491 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15879212|dip:DIP-187741E|imex:IM-16491-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_011013133.1|dip:DIP-59388N|ensemblbacteria:AAL82113(transcript)|ensemblbacteria:PF1989(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009306"(protein secretion)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:3MP7 refseq:WP_011012942.1|dip:DIP-59389N|ensemblbacteria:AAL81925(transcript)|ensemblbacteria:PF1801(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0016021"(integral component of membrane)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR026593|interpro:IPR030659|rcsb pdb:3MP7 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:7oJc8cnb/nHaxmhrS0/B0UUtEJk186497 rogid:s4SZ6eaORX1uBBtxFgjD/kTeWRU186497 rigid:yjzEse6UST7G1M6Nagz4SiU93mU false his tag:?-? sufficient binding region:1-453 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q8TZK2 uniprotkb:Q8TZH7 intact:EBI-9025109|ensemblbacteria:AAL82113 intact:EBI-15879198|ensemblbacteria:AAL82140 psi-mi:sece_pyrfu(display_long)|uniprotkb:secE(gene name)|psi-mi:secE(display_short)|uniprotkb:Protein transport protein Sec61 gamma subunit homolog(gene name synonym)|uniprotkb:PF1989(locus name) psi-mi:secg_pyrfu(display_long)|uniprotkb:secG(gene name)|psi-mi:secG(display_short)|uniprotkb:Protein transport protein Sec61 subunit beta homolog(gene name synonym)|uniprotkb:PF2016(locus name) psi-mi:"MI:0226"(ion exchange chromatography) Egea et al. (2010) pubmed:20855604|doi:10.1073/pnas.1012556107|imex:IM-16491 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15879294|imex:IM-16491-6|dip:DIP-187741E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_011013133.1|dip:DIP-59388N|ensemblbacteria:AAL82113(transcript)|ensemblbacteria:PF1989(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009306"(protein secretion)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:3MP7 ensemblbacteria:AAL82140(transcript)|ensemblbacteria:PF2016(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR023531|refseq:WP_011013161.1|dip:DIP-59390N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:7oJc8cnb/nHaxmhrS0/B0UUtEJk186497 rogid:qj6r3k3Fs5rPWSP0Flz1EX694xc186497 rigid:yjzEse6UST7G1M6Nagz4SiU93mU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TZK2 uniprotkb:Q8U019 intact:EBI-9025109|ensemblbacteria:AAL82113 intact:EBI-9025098|ensemblbacteria:AAL81925 psi-mi:sece_pyrfu(display_long)|uniprotkb:secE(gene name)|psi-mi:secE(display_short)|uniprotkb:Protein transport protein Sec61 gamma subunit homolog(gene name synonym)|uniprotkb:PF1989(locus name) psi-mi:secy_pyrfu(display_long)|uniprotkb:secY(gene name)|psi-mi:secY(display_short)|uniprotkb:Protein transport protein SEC61 subunit alpha homolog(gene name synonym)|uniprotkb:PF1801(locus name) psi-mi:"MI:0226"(ion exchange chromatography) Egea et al. (2010) pubmed:20855604|doi:10.1073/pnas.1012556107|imex:IM-16491 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15879294|imex:IM-16491-6|dip:DIP-187741E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_011013133.1|dip:DIP-59388N|ensemblbacteria:AAL82113(transcript)|ensemblbacteria:PF1989(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009306"(protein secretion)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:3MP7 refseq:WP_011012942.1|dip:DIP-59389N|ensemblbacteria:AAL81925(transcript)|ensemblbacteria:PF1801(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0016021"(integral component of membrane)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR026593|interpro:IPR030659|rcsb pdb:3MP7 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:7oJc8cnb/nHaxmhrS0/B0UUtEJk186497 rogid:s4SZ6eaORX1uBBtxFgjD/kTeWRU186497 rigid:yjzEse6UST7G1M6Nagz4SiU93mU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)