#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0AFI2	uniprotkb:P22523	intact:EBI-878544|uniprotkb:O69154|uniprotkb:P20082|uniprotkb:Q2M9I1|ensemblbacteria:AAC76055|ensemblbacteria:BAE77075	intact:EBI-542943|uniprotkb:P71227|uniprotkb:P77164|uniprotkb:Q47398|ensemblbacteria:AAC74010|ensemblbacteria:BAA35670	psi-mi:parc_ecoli(display_long)|uniprotkb:Topoisomerase IV subunit A(gene name synonym)|uniprotkb:parC(gene name)|psi-mi:parC(display_short)|uniprotkb:b3019(locus name)|uniprotkb:JW2987(locus name)	psi-mi:mukb_ecoli(display_long)|uniprotkb:mukB(gene name)|psi-mi:mukB(display_short)|uniprotkb:b0924(locus name)|uniprotkb:JW0907(locus name)|uniprotkb:Structural maintenance of chromosome-related protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hayama et al. (2010)	pubmed:20696938|doi:10.1073/pnas.1008140107|imex:IM-17107	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15870361|imex:IM-17107-1|dip:DIP-188076E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001281881.1|refseq:NP_417491.1|dip:DIP-36030N|ensemblbacteria:AAC76055(transcript)|ensemblbacteria:b3019(gene)|ensemblbacteria:BAE77075(gene)|ensemblbacteria:BAE77075(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009330"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex")|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030541"(plasmid partitioning)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR005742(DNA topoisomerase IV, subunit A, Gram-negative)|interpro:IPR006691(DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel)|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR035516|rcsb pdb:1ZVT|rcsb pdb:1ZVU|rcsb pdb:4MN4	ensemblbacteria:AAC74010(transcript)|ensemblbacteria:b0924(gene)|ensemblbacteria:BAA35670(gene)|ensemblbacteria:BAA35670(transcript)|go:"GO:0000796"(condensin complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR007406(Prokaryotic chromosome segregation and condensation protein MukB, N-terminal)|interpro:IPR012090(Chromosome partition protein MukB)|interpro:IPR027417|interpro:IPR032520|interpro:IPR042501|rcsb pdb:1QHL|rcsb pdb:2WMM|rcsb pdb:3IBP|rcsb pdb:4MN4|rcsb pdb:6H2X|refseq:NP_415444.1|refseq:WP_000572698.1|mint:P22523|dip:DIP-10273N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:gdxqDlVCB3ICn2GcuIdn4wL8vh483333	rogid:b6yYfft0JB9eIeLBz44jDxJlKXo83333	rigid:hhBUcBMks20tME2TOfcsrVha3Z0	false	-	ha tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P0AFI2	uniprotkb:P22523	intact:EBI-878544|uniprotkb:O69154|uniprotkb:P20082|uniprotkb:Q2M9I1|ensemblbacteria:AAC76055|ensemblbacteria:BAE77075	intact:EBI-542943|uniprotkb:P71227|uniprotkb:P77164|uniprotkb:Q47398|ensemblbacteria:AAC74010|ensemblbacteria:BAA35670	psi-mi:parc_ecoli(display_long)|uniprotkb:Topoisomerase IV subunit A(gene name synonym)|uniprotkb:parC(gene name)|psi-mi:parC(display_short)|uniprotkb:b3019(locus name)|uniprotkb:JW2987(locus name)	psi-mi:mukb_ecoli(display_long)|uniprotkb:mukB(gene name)|psi-mi:mukB(display_short)|uniprotkb:b0924(locus name)|uniprotkb:JW0907(locus name)|uniprotkb:Structural maintenance of chromosome-related protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hayama et al. (2010)	pubmed:20696938|doi:10.1073/pnas.1008140107|imex:IM-17107	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15870380|imex:IM-17107-2|dip:DIP-188076E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001281881.1|refseq:NP_417491.1|dip:DIP-36030N|ensemblbacteria:AAC76055(transcript)|ensemblbacteria:b3019(gene)|ensemblbacteria:BAE77075(gene)|ensemblbacteria:BAE77075(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009330"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex")|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030541"(plasmid partitioning)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR005742(DNA topoisomerase IV, subunit A, Gram-negative)|interpro:IPR006691(DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel)|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR035516|rcsb pdb:1ZVT|rcsb pdb:1ZVU|rcsb pdb:4MN4	ensemblbacteria:AAC74010(transcript)|ensemblbacteria:b0924(gene)|ensemblbacteria:BAA35670(gene)|ensemblbacteria:BAA35670(transcript)|go:"GO:0000796"(condensin complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR007406(Prokaryotic chromosome segregation and condensation protein MukB, N-terminal)|interpro:IPR012090(Chromosome partition protein MukB)|interpro:IPR027417|interpro:IPR032520|interpro:IPR042501|rcsb pdb:1QHL|rcsb pdb:2WMM|rcsb pdb:3IBP|rcsb pdb:4MN4|rcsb pdb:6H2X|refseq:NP_415444.1|refseq:WP_000572698.1|mint:P22523|dip:DIP-10273N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:gdxqDlVCB3ICn2GcuIdn4wL8vh483333	rogid:b6yYfft0JB9eIeLBz44jDxJlKXo83333	rigid:hhBUcBMks20tME2TOfcsrVha3Z0	false	-	ha tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AFI2	uniprotkb:P22523	intact:EBI-878544|uniprotkb:O69154|uniprotkb:P20082|uniprotkb:Q2M9I1|ensemblbacteria:AAC76055|ensemblbacteria:BAE77075	intact:EBI-542943|uniprotkb:P71227|uniprotkb:P77164|uniprotkb:Q47398|ensemblbacteria:AAC74010|ensemblbacteria:BAA35670	psi-mi:parc_ecoli(display_long)|uniprotkb:Topoisomerase IV subunit A(gene name synonym)|uniprotkb:parC(gene name)|psi-mi:parC(display_short)|uniprotkb:b3019(locus name)|uniprotkb:JW2987(locus name)	psi-mi:mukb_ecoli(display_long)|uniprotkb:mukB(gene name)|psi-mi:mukB(display_short)|uniprotkb:b0924(locus name)|uniprotkb:JW0907(locus name)|uniprotkb:Structural maintenance of chromosome-related protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hayama et al. (2010)	pubmed:20696938|doi:10.1073/pnas.1008140107|imex:IM-17107	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15870399|imex:IM-17107-3|dip:DIP-188076E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001281881.1|refseq:NP_417491.1|dip:DIP-36030N|ensemblbacteria:AAC76055(transcript)|ensemblbacteria:b3019(gene)|ensemblbacteria:BAE77075(gene)|ensemblbacteria:BAE77075(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009330"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex")|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030541"(plasmid partitioning)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR005742(DNA topoisomerase IV, subunit A, Gram-negative)|interpro:IPR006691(DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel)|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR035516|rcsb pdb:1ZVT|rcsb pdb:1ZVU|rcsb pdb:4MN4	ensemblbacteria:AAC74010(transcript)|ensemblbacteria:b0924(gene)|ensemblbacteria:BAA35670(gene)|ensemblbacteria:BAA35670(transcript)|go:"GO:0000796"(condensin complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR007406(Prokaryotic chromosome segregation and condensation protein MukB, N-terminal)|interpro:IPR012090(Chromosome partition protein MukB)|interpro:IPR027417|interpro:IPR032520|interpro:IPR042501|rcsb pdb:1QHL|rcsb pdb:2WMM|rcsb pdb:3IBP|rcsb pdb:4MN4|rcsb pdb:6H2X|refseq:NP_415444.1|refseq:WP_000572698.1|mint:P22523|dip:DIP-10273N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:gdxqDlVCB3ICn2GcuIdn4wL8vh483333	rogid:b6yYfft0JB9eIeLBz44jDxJlKXo83333	rigid:hhBUcBMks20tME2TOfcsrVha3Z0	false	ha tag:n-n|sufficient binding region:497-752|necessary binding region:696-752|mutation disrupting interaction:729-729,705-705|mutation disrupting interaction:705-705|mutation disrupting interaction:729-729	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)