#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P54287 uniprotkb:P55040 intact:EBI-8028596|intact:MINT-8407486|ensembl:ENSRNOP00000073026 intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497 psi-mi:cacb3_rat(display_long)|uniprotkb:Cacnb3(gene name)|psi-mi:Cacnb3(display_short)|uniprotkb:Cacnlb3(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 3(gene name synonym) psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fan et al. (2010) pubmed:20679232|doi:10.1073/pnas.1007543107|imex:IM-16463 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15868205|imex:IM-16463-1|dip:DIP-187702E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036960.1|rgd:2248|dip:DIP-59370N|ensembl:ENSRNOG00000054274(gene)|ensembl:ENSRNOT00000081206(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0045202"(synapse)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|go:"GO:1902630"(regulation of membrane hyperpolarization)|go:"GO:1905788"(negative regulation of detection of mechanical stimulus involved in sensory perception of touch)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR008079(Voltage-dependent calcium channel, L-type, beta-3 subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035760|interpro:IPR036028|mint:P54287|rcsb pdb:1VYT|rcsb pdb:1VYU|reactome:R-RNO-112308|reactome:R-RNO-422356 refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N psi-mi:"MI:0465"(dip) comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:qioxo4m/B/2M8vhhTS2urRHOmO010116 rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606 rigid:t1WiGp+4wldoPprt1XqR5mRlwOI false myc tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P27884 uniprotkb:P55040 intact:EBI-15685548|uniprotkb:P27883 intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497 psi-mi:cac1a_rabit(display_long)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym) psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fan et al. (2010) pubmed:20679232|doi:10.1073/pnas.1007543107|imex:IM-16463 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15868226|imex:IM-16463-2|dip:DIP-187704E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0070588"(calcium ion transmembrane transport)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|rcsb pdb:3DVM|go:"GO:0046872"(metal ion binding)|refseq:NP_001095163.1|dip:DIP-29591N refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:P5k43jEFL3aTiGkUx7KYNEPXRmA9986 rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606 rigid:VbZLbcFYlhKqrSE7e6SKb/SuItM false flag tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P55040 uniprotkb:P54287 intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497 intact:EBI-8028596|intact:MINT-8407486|ensembl:ENSRNOP00000073026 psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym) psi-mi:cacb3_rat(display_long)|uniprotkb:Cacnb3(gene name)|psi-mi:Cacnb3(display_short)|uniprotkb:Cacnlb3(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fan et al. (2010) pubmed:20679232|doi:10.1073/pnas.1007543107|imex:IM-16463 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15868247|imex:IM-16463-3|dip:DIP-187703E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N refseq:NP_036960.1|rgd:2248|dip:DIP-59370N|ensembl:ENSRNOG00000054274(gene)|ensembl:ENSRNOT00000081206(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0045202"(synapse)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|go:"GO:1902630"(regulation of membrane hyperpolarization)|go:"GO:1905788"(negative regulation of detection of mechanical stimulus involved in sensory perception of touch)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR008079(Voltage-dependent calcium channel, L-type, beta-3 subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035760|interpro:IPR036028|mint:P54287|rcsb pdb:1VYT|rcsb pdb:1VYU|reactome:R-RNO-112308|reactome:R-RNO-422356 psi-mi:"MI:0465"(dip) - comment:mint full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606 rogid:qioxo4m/B/2M8vhhTS2urRHOmO010116 rigid:mlTStZvx10vsm0CvakFAWljtQg0 false ha tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P55040 uniprotkb:P27884 intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497 intact:EBI-15685548|uniprotkb:P27883 psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym) psi-mi:cac1a_rabit(display_long)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fan et al. (2010) pubmed:20679232|doi:10.1073/pnas.1007543107|imex:IM-16463 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15868247|imex:IM-16463-3|dip:DIP-187703E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0070588"(calcium ion transmembrane transport)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|rcsb pdb:3DVM|go:"GO:0046872"(metal ion binding)|refseq:NP_001095163.1|dip:DIP-29591N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606 rogid:P5k43jEFL3aTiGkUx7KYNEPXRmA9986 rigid:mlTStZvx10vsm0CvakFAWljtQg0 false ha tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)