#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O15066 uniprotkb:P51795 intact:EBI-3931791|uniprotkb:E1P5M5|uniprotkb:B2RMP4|ensembl:ENSP00000364864|uniprotkb:B4DSR5 intact:EBI-13619183|ensembl:ENSP00000365256|ensembl:ENSP00000365259|uniprotkb:A1L475|uniprotkb:B3KPN6|uniprotkb:Q5JQD5|uniprotkb:Q7RTN8 psi-mi:kif3b_human(display_long)|uniprotkb:KIF3B(gene name)|psi-mi:KIF3B(display_short)|uniprotkb:KIAA0359(gene name synonym)|uniprotkb:HH0048(gene name synonym)|uniprotkb:Microtubule plus end-directed kinesin motor 3B(gene name synonym) psi-mi:clcn5_human(display_long)|uniprotkb:CLCN5(gene name)|psi-mi:CLCN5(display_short)|uniprotkb:CLCK2(gene name synonym)|uniprotkb:Chloride channel protein 5(gene name synonym)|uniprotkb:Chloride transporter ClC-5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Reed et al. (2010) pubmed:19940036|imex:IM-26117 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-13643711|imex:IM-26117-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000101350(gene)|ensembl:ENST00000375712(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005873"(plus-end kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016939"(kinesin II complex)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0036372"(opsin transport)|go:"GO:0042073"(intraciliary transport)|go:"GO:0043197"(dendritic spine)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097542"(ciliary tip)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|rcsb pdb:3B6U|reactome:R-HSA-1445148|reactome:R-HSA-2132295|reactome:R-HSA-5620924|reactome:R-HSA-6811434|reactome:R-HSA-983189|go:"GO:0016020"(membrane)|refseq:NP_004789.1 ensembl:ENSG00000171365(gene)|ensembl:ENST00000376088(transcript)|ensembl:ENST00000376091(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007588"(excretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015299"("solute:proton antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002247(Chloride channel CLC-5)|interpro:IPR014743(Chloride channel, core)|rcsb pdb:2J9L|rcsb pdb:2JA3|reactome:R-HSA-2672351|refseq:NP_000075.1|refseq:NP_001121370.1|refseq:NP_001121371.1|refseq:NP_001269092.1|dip:DIP-29263N - - - figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/02/08 2020/08/15 rogid:06eFJUfpcyifNpmXa2wMQQmLccg9606 rogid:8f3zMSNelJ4fxwOH6jiOgfNrhQc9606 rigid:mSwztFSy0rygqhAx/z+mKTUSLIw false sufficient binding region:410-747 sufficient binding region:621-816 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15066 uniprotkb:P51795 intact:EBI-3931791|uniprotkb:E1P5M5|uniprotkb:B2RMP4|ensembl:ENSP00000364864|uniprotkb:B4DSR5 intact:EBI-13619183|ensembl:ENSP00000365256|ensembl:ENSP00000365259|uniprotkb:A1L475|uniprotkb:B3KPN6|uniprotkb:Q5JQD5|uniprotkb:Q7RTN8 psi-mi:kif3b_human(display_long)|uniprotkb:KIF3B(gene name)|psi-mi:KIF3B(display_short)|uniprotkb:KIAA0359(gene name synonym)|uniprotkb:HH0048(gene name synonym)|uniprotkb:Microtubule plus end-directed kinesin motor 3B(gene name synonym) psi-mi:clcn5_human(display_long)|uniprotkb:CLCN5(gene name)|psi-mi:CLCN5(display_short)|uniprotkb:CLCK2(gene name synonym)|uniprotkb:Chloride channel protein 5(gene name synonym)|uniprotkb:Chloride transporter ClC-5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Reed et al. (2010) pubmed:19940036|imex:IM-26117 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-13643727|imex:IM-26117-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000101350(gene)|ensembl:ENST00000375712(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005873"(plus-end kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016939"(kinesin II complex)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0036372"(opsin transport)|go:"GO:0042073"(intraciliary transport)|go:"GO:0043197"(dendritic spine)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097542"(ciliary tip)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|rcsb pdb:3B6U|reactome:R-HSA-1445148|reactome:R-HSA-2132295|reactome:R-HSA-5620924|reactome:R-HSA-6811434|reactome:R-HSA-983189|go:"GO:0016020"(membrane)|refseq:NP_004789.1 ensembl:ENSG00000171365(gene)|ensembl:ENST00000376088(transcript)|ensembl:ENST00000376091(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007588"(excretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015299"("solute:proton antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002247(Chloride channel CLC-5)|interpro:IPR014743(Chloride channel, core)|rcsb pdb:2J9L|rcsb pdb:2JA3|reactome:R-HSA-2672351|refseq:NP_000075.1|refseq:NP_001121370.1|refseq:NP_001121371.1|refseq:NP_001269092.1|dip:DIP-29263N - - - figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/02/08 2020/08/15 rogid:06eFJUfpcyifNpmXa2wMQQmLccg9606 rogid:8f3zMSNelJ4fxwOH6jiOgfNrhQc9606 rigid:mSwztFSy0rygqhAx/z+mKTUSLIw false - sufficient binding region:621-816 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15066 uniprotkb:P51795 intact:EBI-3931791|uniprotkb:E1P5M5|uniprotkb:B2RMP4|ensembl:ENSP00000364864|uniprotkb:B4DSR5 intact:EBI-13619183|ensembl:ENSP00000365256|ensembl:ENSP00000365259|uniprotkb:A1L475|uniprotkb:B3KPN6|uniprotkb:Q5JQD5|uniprotkb:Q7RTN8 psi-mi:kif3b_human(display_long)|uniprotkb:KIF3B(gene name)|psi-mi:KIF3B(display_short)|uniprotkb:KIAA0359(gene name synonym)|uniprotkb:HH0048(gene name synonym)|uniprotkb:Microtubule plus end-directed kinesin motor 3B(gene name synonym) psi-mi:clcn5_human(display_long)|uniprotkb:CLCN5(gene name)|psi-mi:CLCN5(display_short)|uniprotkb:CLCK2(gene name synonym)|uniprotkb:Chloride channel protein 5(gene name synonym)|uniprotkb:Chloride transporter ClC-5(gene name synonym) psi-mi:"MI:0096"(pull down) Reed et al. (2010) pubmed:19940036|imex:IM-26117 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-13643743|imex:IM-26117-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000101350(gene)|ensembl:ENST00000375712(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005873"(plus-end kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016939"(kinesin II complex)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0036372"(opsin transport)|go:"GO:0042073"(intraciliary transport)|go:"GO:0043197"(dendritic spine)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097542"(ciliary tip)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|rcsb pdb:3B6U|reactome:R-HSA-1445148|reactome:R-HSA-2132295|reactome:R-HSA-5620924|reactome:R-HSA-6811434|reactome:R-HSA-983189|go:"GO:0016020"(membrane)|refseq:NP_004789.1 ensembl:ENSG00000171365(gene)|ensembl:ENST00000376088(transcript)|ensembl:ENST00000376091(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007588"(excretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015299"("solute:proton antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002247(Chloride channel CLC-5)|interpro:IPR014743(Chloride channel, core)|rcsb pdb:2J9L|rcsb pdb:2JA3|reactome:R-HSA-2672351|refseq:NP_000075.1|refseq:NP_001121370.1|refseq:NP_001121371.1|refseq:NP_001269092.1|dip:DIP-29263N - - - figure legend:1C|comment:Two bands were detected for CLC-5.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/02/08 2020/08/15 rogid:06eFJUfpcyifNpmXa2wMQQmLccg9606 rogid:8f3zMSNelJ4fxwOH6jiOgfNrhQc9606 rigid:mSwztFSy0rygqhAx/z+mKTUSLIw false glutathione s tranferase tag:n-n|sufficient binding region:346..346-747..747 sufficient binding region:621-816|35s radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q9WVD4 uniprotkb:Q61771 intact:EBI-8366405|intact:MINT-4090917|uniprotkb:B1AXN0|uniprotkb:B1ATV0|ensembl:ENSMUSP00000111412 intact:EBI-6395332|ensembl:ENSMUSP00000028977|uniprotkb:Q3UFZ8|uniprotkb:Q8BNH4 psi-mi:clcn5_mouse(display_long)|uniprotkb:Clcn5(gene name)|psi-mi:Clcn5(display_short)|uniprotkb:Clc5(gene name synonym)|uniprotkb:Chloride transporter ClC-5(gene name synonym)|uniprotkb:Chloride channel protein 5(gene name synonym) psi-mi:kif3b_mouse(display_long)|uniprotkb:Kif3b(gene name)|psi-mi:Kif3b(display_short)|uniprotkb:Microtubule plus end-directed kinesin motor 3B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Reed et al. (2010) pubmed:19940036|imex:IM-26117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-13643770|imex:IM-26117-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001230691.1|refseq:NP_057900.3|ensembl:ENSMUSG00000004317(gene)|ensembl:ENSMUST00000115746(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0015299"("solute:proton antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002247(Chloride channel CLC-5)|interpro:IPR014743(Chloride channel, core)|mint:Q9WVD4|reactome:R-MMU-2672351 ensembl:ENSMUSG00000027475(gene)|ensembl:ENSMUST00000028977(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016939"(kinesin II complex)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0036372"(opsin transport)|go:"GO:0042073"(intraciliary transport)|go:"GO:0043197"(dendritic spine)|go:"GO:0060271"(cilium assembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|reactome:R-MMU-2132295|reactome:R-MMU-5620924|reactome:R-MMU-6811434|reactome:R-MMU-983189|refseq:NP_032470.3 - comment:mint|function:Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May play an important role in renal tubular function - figure legend:1D-1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-kidney)|taxid:10090(Mus musculus) - 2017/02/08 2020/08/15 rogid:V4yqAKhRTpoDXGznm7TeMtDRgUY10090 rogid:JsWP3UOgu6c3iZWc6pr3aU+hNrs10090 rigid:BquVVAX6nkSooNteIoUt0JEsNOc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P28741 uniprotkb:P70188 intact:EBI-6169413|ensembl:ENSMUSP00000112782|uniprotkb:Q7TSZ7 intact:EBI-6169443|ensembl:ENSMUSP00000027877|uniprotkb:P70189|uniprotkb:Q6GTS3 psi-mi:kif3a_mouse(display_long)|uniprotkb:Kif3a(gene name)|psi-mi:Kif3a(display_short)|uniprotkb:Kif3(gene name synonym)|uniprotkb:Microtubule plus end-directed kinesin motor 3A(gene name synonym) psi-mi:kifa3_mouse(display_long)|uniprotkb:Kifap3(gene name)|psi-mi:Kifap3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Reed et al. (2010) pubmed:19940036|imex:IM-26117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-13643774|imex:IM-26117-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000018395(gene)|ensembl:ENSMUST00000120613(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001822"(kidney development)|go:"GO:0001947"(heart looping)|go:"GO:0003341"(cilium movement)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008544"(epidermis development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016939"(kinesin II complex)|go:"GO:0019894"(kinesin binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0021915"(neural tube development)|go:"GO:0030507"(spectrin binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0036334"(epidermal stem cell homeostasis)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1902414"(protein localization to cell junction)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905128"(positive regulation of axo-dendritic protein transport)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990939"|go:"GO:2000771"(positive regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:P28741|rcsb pdb:5JVR|rcsb pdb:5JX1|reactome:R-MMU-2132295|reactome:R-MMU-5610787|reactome:R-MMU-5620924|reactome:R-MMU-5635838|reactome:R-MMU-983189|reactome:R-MMU-6811434|refseq:NP_001277734.1|refseq:NP_001277735.1|refseq:NP_032469.2|dip:DIP-46318N interpro:IPR016024(Armadillo-type fold)|reactome:R-MMU-2132295|reactome:R-MMU-5620924|reactome:R-MMU-6811434|reactome:R-MMU-983189|ensembl:ENSMUSG00000026585(gene)|ensembl:ENSMUST00000027877(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016939"(kinesin II complex)|go:"GO:0019894"(kinesin binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044782"(cilium organization)|go:"GO:0046587"(positive regulation of calcium-dependent cell-cell adhesion)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1990075"(periciliary membrane compartment)|interpro:IPR000225(Armadillo)|interpro:IPR008658(Kinesin-associated)|go:"GO:0000794"(condensed nuclear chromosome)|refseq:NP_001292572.1|refseq:NP_034759.1 - - - figure legend:1D-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-kidney)|taxid:10090(Mus musculus) - 2017/02/08 2017/02/09 rogid:3P8b4UgzwNTTXf1KVCB6+T+1+bk10090 rogid:ZPQUT3r4ZkEieMyTWZeER0I4g+c10090 rigid:K6g6mxlsgGnW5q0k2WeT9pKoYvc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q61771 uniprotkb:P28741 intact:EBI-6395332|ensembl:ENSMUSP00000028977|uniprotkb:Q3UFZ8|uniprotkb:Q8BNH4 intact:EBI-6169413|ensembl:ENSMUSP00000112782|uniprotkb:Q7TSZ7 psi-mi:kif3b_mouse(display_long)|uniprotkb:Kif3b(gene name)|psi-mi:Kif3b(display_short)|uniprotkb:Microtubule plus end-directed kinesin motor 3B(gene name synonym) psi-mi:kif3a_mouse(display_long)|uniprotkb:Kif3a(gene name)|psi-mi:Kif3a(display_short)|uniprotkb:Kif3(gene name synonym)|uniprotkb:Microtubule plus end-directed kinesin motor 3A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Reed et al. (2010) pubmed:19940036|imex:IM-26117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-13643778|imex:IM-26117-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027475(gene)|ensembl:ENSMUST00000028977(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016939"(kinesin II complex)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0036372"(opsin transport)|go:"GO:0042073"(intraciliary transport)|go:"GO:0043197"(dendritic spine)|go:"GO:0060271"(cilium assembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|reactome:R-MMU-2132295|reactome:R-MMU-5620924|reactome:R-MMU-6811434|reactome:R-MMU-983189|refseq:NP_032470.3 ensembl:ENSMUSG00000018395(gene)|ensembl:ENSMUST00000120613(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001822"(kidney development)|go:"GO:0001947"(heart looping)|go:"GO:0003341"(cilium movement)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008544"(epidermis development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016939"(kinesin II complex)|go:"GO:0019894"(kinesin binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0021915"(neural tube development)|go:"GO:0030507"(spectrin binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0036334"(epidermal stem cell homeostasis)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1902414"(protein localization to cell junction)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905128"(positive regulation of axo-dendritic protein transport)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990939"|go:"GO:2000771"(positive regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:P28741|rcsb pdb:5JVR|rcsb pdb:5JX1|reactome:R-MMU-2132295|reactome:R-MMU-5610787|reactome:R-MMU-5620924|reactome:R-MMU-5635838|reactome:R-MMU-983189|reactome:R-MMU-6811434|refseq:NP_001277734.1|refseq:NP_001277735.1|refseq:NP_032469.2|dip:DIP-46318N - - - figure legend:1D-3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-kidney)|taxid:10090(Mus musculus) - 2017/02/08 2017/02/09 rogid:JsWP3UOgu6c3iZWc6pr3aU+hNrs10090 rogid:3P8b4UgzwNTTXf1KVCB6+T+1+bk10090 rigid:8n6wAbdB1E1qbiOZ6T/wReN1GQw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q61771 uniprotkb:P70188 intact:EBI-6395332|ensembl:ENSMUSP00000028977|uniprotkb:Q3UFZ8|uniprotkb:Q8BNH4 intact:EBI-6169443|ensembl:ENSMUSP00000027877|uniprotkb:P70189|uniprotkb:Q6GTS3 psi-mi:kif3b_mouse(display_long)|uniprotkb:Kif3b(gene name)|psi-mi:Kif3b(display_short)|uniprotkb:Microtubule plus end-directed kinesin motor 3B(gene name synonym) psi-mi:kifa3_mouse(display_long)|uniprotkb:Kifap3(gene name)|psi-mi:Kifap3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Reed et al. (2010) pubmed:19940036|imex:IM-26117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-13643778|imex:IM-26117-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027475(gene)|ensembl:ENSMUST00000028977(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016939"(kinesin II complex)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0036372"(opsin transport)|go:"GO:0042073"(intraciliary transport)|go:"GO:0043197"(dendritic spine)|go:"GO:0060271"(cilium assembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|reactome:R-MMU-2132295|reactome:R-MMU-5620924|reactome:R-MMU-6811434|reactome:R-MMU-983189|refseq:NP_032470.3 interpro:IPR016024(Armadillo-type fold)|reactome:R-MMU-2132295|reactome:R-MMU-5620924|reactome:R-MMU-6811434|reactome:R-MMU-983189|ensembl:ENSMUSG00000026585(gene)|ensembl:ENSMUST00000027877(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016939"(kinesin II complex)|go:"GO:0019894"(kinesin binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044782"(cilium organization)|go:"GO:0046587"(positive regulation of calcium-dependent cell-cell adhesion)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1990075"(periciliary membrane compartment)|interpro:IPR000225(Armadillo)|interpro:IPR008658(Kinesin-associated)|go:"GO:0000794"(condensed nuclear chromosome)|refseq:NP_001292572.1|refseq:NP_034759.1 - - - figure legend:1D-3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-kidney)|taxid:10090(Mus musculus) - 2017/02/08 2017/02/09 rogid:JsWP3UOgu6c3iZWc6pr3aU+hNrs10090 rogid:ZPQUT3r4ZkEieMyTWZeER0I4g+c10090 rigid:8n6wAbdB1E1qbiOZ6T/wReN1GQw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O15066 uniprotkb:P51795 intact:EBI-3931791|uniprotkb:E1P5M5|uniprotkb:B2RMP4|ensembl:ENSP00000364864|uniprotkb:B4DSR5 intact:EBI-13619183|ensembl:ENSP00000365256|ensembl:ENSP00000365259|uniprotkb:A1L475|uniprotkb:B3KPN6|uniprotkb:Q5JQD5|uniprotkb:Q7RTN8 psi-mi:kif3b_human(display_long)|uniprotkb:KIF3B(gene name)|psi-mi:KIF3B(display_short)|uniprotkb:KIAA0359(gene name synonym)|uniprotkb:HH0048(gene name synonym)|uniprotkb:Microtubule plus end-directed kinesin motor 3B(gene name synonym) psi-mi:clcn5_human(display_long)|uniprotkb:CLCN5(gene name)|psi-mi:CLCN5(display_short)|uniprotkb:CLCK2(gene name synonym)|uniprotkb:Chloride channel protein 5(gene name synonym)|uniprotkb:Chloride transporter ClC-5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reed et al. (2010) pubmed:19940036|imex:IM-26117 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-13643799|imex:IM-26117-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000101350(gene)|ensembl:ENST00000375712(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005873"(plus-end kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016939"(kinesin II complex)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0036372"(opsin transport)|go:"GO:0042073"(intraciliary transport)|go:"GO:0043197"(dendritic spine)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097542"(ciliary tip)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|rcsb pdb:3B6U|reactome:R-HSA-1445148|reactome:R-HSA-2132295|reactome:R-HSA-5620924|reactome:R-HSA-6811434|reactome:R-HSA-983189|go:"GO:0016020"(membrane)|refseq:NP_004789.1 ensembl:ENSG00000171365(gene)|ensembl:ENST00000376088(transcript)|ensembl:ENST00000376091(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007588"(excretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015299"("solute:proton antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002247(Chloride channel CLC-5)|interpro:IPR014743(Chloride channel, core)|rcsb pdb:2J9L|rcsb pdb:2JA3|reactome:R-HSA-2672351|refseq:NP_000075.1|refseq:NP_001121370.1|refseq:NP_001121371.1|refseq:NP_001269092.1|dip:DIP-29263N - - - figure legend:1 E/F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/02/08 2020/08/15 rogid:06eFJUfpcyifNpmXa2wMQQmLccg9606 rogid:8f3zMSNelJ4fxwOH6jiOgfNrhQc9606 rigid:mSwztFSy0rygqhAx/z+mKTUSLIw false ha tag:?-?|sufficient binding region:346..346-579..579|sufficient binding region:580..580-747..747 myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O15066 uniprotkb:P51795 intact:EBI-3931791|uniprotkb:E1P5M5|uniprotkb:B2RMP4|ensembl:ENSP00000364864|uniprotkb:B4DSR5 intact:EBI-13619183|ensembl:ENSP00000365256|ensembl:ENSP00000365259|uniprotkb:A1L475|uniprotkb:B3KPN6|uniprotkb:Q5JQD5|uniprotkb:Q7RTN8 psi-mi:kif3b_human(display_long)|uniprotkb:KIF3B(gene name)|psi-mi:KIF3B(display_short)|uniprotkb:KIAA0359(gene name synonym)|uniprotkb:HH0048(gene name synonym)|uniprotkb:Microtubule plus end-directed kinesin motor 3B(gene name synonym) psi-mi:clcn5_human(display_long)|uniprotkb:CLCN5(gene name)|psi-mi:CLCN5(display_short)|uniprotkb:CLCK2(gene name synonym)|uniprotkb:Chloride channel protein 5(gene name synonym)|uniprotkb:Chloride transporter ClC-5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reed et al. (2010) pubmed:19940036|imex:IM-26117 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-13643809|imex:IM-26117-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000101350(gene)|ensembl:ENST00000375712(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005873"(plus-end kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016939"(kinesin II complex)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0036372"(opsin transport)|go:"GO:0042073"(intraciliary transport)|go:"GO:0043197"(dendritic spine)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097542"(ciliary tip)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|rcsb pdb:3B6U|reactome:R-HSA-1445148|reactome:R-HSA-2132295|reactome:R-HSA-5620924|reactome:R-HSA-6811434|reactome:R-HSA-983189|go:"GO:0016020"(membrane)|refseq:NP_004789.1 ensembl:ENSG00000171365(gene)|ensembl:ENST00000376088(transcript)|ensembl:ENST00000376091(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007588"(excretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015299"("solute:proton antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002247(Chloride channel CLC-5)|interpro:IPR014743(Chloride channel, core)|rcsb pdb:2J9L|rcsb pdb:2JA3|reactome:R-HSA-2672351|refseq:NP_000075.1|refseq:NP_001121370.1|refseq:NP_001121371.1|refseq:NP_001269092.1|dip:DIP-29263N - - - figure legend:1 E/Fi|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/02/08 2020/08/15 rogid:06eFJUfpcyifNpmXa2wMQQmLccg9606 rogid:8f3zMSNelJ4fxwOH6jiOgfNrhQc9606 rigid:mSwztFSy0rygqhAx/z+mKTUSLIw false sufficient binding region:346..346-579..579|sufficient binding region:580..580-747..747|ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P51795 uniprotkb:O15066 intact:EBI-13619183|ensembl:ENSP00000365256|ensembl:ENSP00000365259|uniprotkb:A1L475|uniprotkb:B3KPN6|uniprotkb:Q5JQD5|uniprotkb:Q7RTN8 intact:EBI-3931791|uniprotkb:E1P5M5|uniprotkb:B2RMP4|ensembl:ENSP00000364864|uniprotkb:B4DSR5 psi-mi:clcn5_human(display_long)|uniprotkb:CLCN5(gene name)|psi-mi:CLCN5(display_short)|uniprotkb:CLCK2(gene name synonym)|uniprotkb:Chloride channel protein 5(gene name synonym)|uniprotkb:Chloride transporter ClC-5(gene name synonym) psi-mi:kif3b_human(display_long)|uniprotkb:KIF3B(gene name)|psi-mi:KIF3B(display_short)|uniprotkb:KIAA0359(gene name synonym)|uniprotkb:HH0048(gene name synonym)|uniprotkb:Microtubule plus end-directed kinesin motor 3B(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Reed et al. (2010) pubmed:19940036|imex:IM-26117 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-13643831|imex:IM-26117-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171365(gene)|ensembl:ENST00000376088(transcript)|ensembl:ENST00000376091(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007588"(excretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015299"("solute:proton antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002247(Chloride channel CLC-5)|interpro:IPR014743(Chloride channel, core)|rcsb pdb:2J9L|rcsb pdb:2JA3|reactome:R-HSA-2672351|refseq:NP_000075.1|refseq:NP_001121370.1|refseq:NP_001121371.1|refseq:NP_001269092.1|dip:DIP-29263N ensembl:ENSG00000101350(gene)|ensembl:ENST00000375712(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005873"(plus-end kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016939"(kinesin II complex)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0036372"(opsin transport)|go:"GO:0042073"(intraciliary transport)|go:"GO:0043197"(dendritic spine)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097542"(ciliary tip)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|rcsb pdb:3B6U|reactome:R-HSA-1445148|reactome:R-HSA-2132295|reactome:R-HSA-5620924|reactome:R-HSA-6811434|reactome:R-HSA-983189|go:"GO:0016020"(membrane)|refseq:NP_004789.1 go:"GO:0005886"(plasma membrane) - - figure legend:2A|comment:CLC-5 was concentrated at the plasma membrane, and in punctate structures throughout the cytoplasm, where it showed partial colocalization with KIF3B.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/02/08 2020/08/15 rogid:8f3zMSNelJ4fxwOH6jiOgfNrhQc9606 rogid:06eFJUfpcyifNpmXa2wMQQmLccg9606 rigid:mSwztFSy0rygqhAx/z+mKTUSLIw false red fluorescent protein tag:n-n green fluorescent protein tag:n-n - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)