#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O00206-1	uniprotkb:P49278	intact:EBI-15745059|ensembl:ENSP00000363089	intact:EBI-15745025	psi-mi:o00206-1(display_long)|uniprotkb:TLR4(gene name)|psi-mi:TLR4(display_short)|uniprotkb:hToll(gene name synonym)	psi-mi:all2_derpt(display_long)|uniprotkb:DERP2(gene name)|psi-mi:DERP2(display_short)|uniprotkb:Allergen Der p II(gene name synonym)|uniprotkb:DPX(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Trompette et al. (2009)	pubmed:19060881|doi:10.1038/nature07548|imex:IM-17804	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:6956(derpt)|taxid:6956(Dermatophagoides pteronyssinus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15745068|imex:IM-17804-2|dip:DIP-189195E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000136869(gene)|ensembl:ENST00000355622(transcript)|intact:EBI-528701(isoform-parent)	go:"GO:0005576"(extracellular region)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR039670|rcsb pdb:1A9V|rcsb pdb:1KTJ|rcsb pdb:6OY4|dip:DIP-59729N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:4flqeyn60Q/64s8vQQHzlYDWz6w9606	rogid:ANbwduc2K+FFtTYKEl5FSfwYkHw6956	rigid:RVmgd8evU5BcgOtfdoPv5vgqrdw	false	yellow fluorescent protein tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9Y6Y9	uniprotkb:P49278	intact:EBI-1539247|uniprotkb:E5RJJ7|uniprotkb:B3Y6A5|ensembl:ENSP00000284818	intact:EBI-15745025	psi-mi:ly96_human(display_long)|uniprotkb:Protein MD-2(gene name synonym)|uniprotkb:ESOP-1(gene name synonym)|uniprotkb:LY96(gene name)|psi-mi:LY96(display_short)|uniprotkb:ESOP1(gene name synonym)|uniprotkb:MD2(gene name synonym)	psi-mi:all2_derpt(display_long)|uniprotkb:DERP2(gene name)|psi-mi:DERP2(display_short)|uniprotkb:Allergen Der p II(gene name synonym)|uniprotkb:DPX(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Trompette et al. (2009)	pubmed:19060881|doi:10.1038/nature07548|imex:IM-17804	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:6956(derpt)|taxid:6956(Dermatophagoides pteronyssinus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15745038|imex:IM-17804-1|dip:DIP-189196E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001182726.1|refseq:NP_056179.3|dip:DIP-38571N|ensembl:ENSG00000154589(gene)|ensembl:ENST00000284818(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001875"(lipopolysaccharide immune receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0015026"(coreceptor activity)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032497"(detection of lipopolysaccharide)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR039217|rcsb pdb:1T2Z|rcsb pdb:2E56|rcsb pdb:2E59|rcsb pdb:2Z65|rcsb pdb:3FXI|rcsb pdb:3ULA|rcsb pdb:4G8A|reactome:R-HSA-1236974|reactome:R-HSA-140534|reactome:R-HSA-166016|reactome:R-HSA-166058|reactome:R-HSA-166166|reactome:R-HSA-2562578|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|reactome:R-HSA-936964|reactome:R-HSA-937041|reactome:R-HSA-937072|reactome:R-HSA-9707616|reactome:R-HSA-975163	go:"GO:0005576"(extracellular region)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR039670|rcsb pdb:1A9V|rcsb pdb:1KTJ|rcsb pdb:6OY4|dip:DIP-59729N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:mudJbbtrzlBXQeXgJNpkEmKeH589606	rogid:ANbwduc2K+FFtTYKEl5FSfwYkHw6956	rigid:JWc7T5NeEXpBe62fiX7nbYpgyQE	false	flag tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P49278	uniprotkb:P49278	intact:EBI-15745025	intact:EBI-15745025	psi-mi:all2_derpt(display_long)|uniprotkb:DERP2(gene name)|psi-mi:DERP2(display_short)|uniprotkb:Allergen Der p II(gene name synonym)|uniprotkb:DPX(gene name synonym)	psi-mi:all2_derpt(display_long)|uniprotkb:DERP2(gene name)|psi-mi:DERP2(display_short)|uniprotkb:Allergen Der p II(gene name synonym)|uniprotkb:DPX(gene name synonym)	psi-mi:"MI:0808"(comigration in sds page)	Trompette et al. (2009)	pubmed:19060881|doi:10.1038/nature07548|imex:IM-17804	taxid:6956(derpt)|taxid:6956(Dermatophagoides pteronyssinus)	taxid:6956(derpt)|taxid:6956(Dermatophagoides pteronyssinus)	psi-mi:"MI:0195"(covalent binding)	psi-mi:"MI:0465"(DIP)	intact:EBI-15745089|imex:IM-17804-3|dip:DIP-189198E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR039670|rcsb pdb:1A9V|rcsb pdb:1KTJ|rcsb pdb:6OY4|dip:DIP-59729N	go:"GO:0005576"(extracellular region)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR039670|rcsb pdb:1A9V|rcsb pdb:1KTJ|rcsb pdb:6OY4|dip:DIP-59729N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)")	-	2017/08/06	2017/08/10	rogid:ANbwduc2K+FFtTYKEl5FSfwYkHw6956	rogid:ANbwduc2K+FFtTYKEl5FSfwYkHw6956	rigid:9AIeg4fYv2v2fYTpGkboFDgW3Zk	false	his tag:c-c	his tag:c-c	-	0	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P08571	uniprotkb:P49278	intact:EBI-3905196|uniprotkb:Q96L99|uniprotkb:Q53XT5|uniprotkb:Q9UNS3|uniprotkb:Q96FR6|ensembl:ENSP00000304236|ensembl:ENSP00000385519	intact:EBI-15745025	psi-mi:cd14_human(display_long)|uniprotkb:CD14(gene name)|psi-mi:CD14(display_short)|uniprotkb:Myeloid cell-specific leucine-rich glycoprotein(gene name synonym)	psi-mi:all2_derpt(display_long)|uniprotkb:DERP2(gene name)|psi-mi:DERP2(display_short)|uniprotkb:Allergen Der p II(gene name synonym)|uniprotkb:DPX(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Trompette et al. (2009)	pubmed:19060881|doi:10.1038/nature07548|imex:IM-17804	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:6956(derpt)|taxid:6956(Dermatophagoides pteronyssinus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15745107|imex:IM-17804-4|dip:DIP-189197E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000582.1|refseq:NP_001035110.1|refseq:NP_001167575.1|refseq:NP_001167576.1|dip:DIP-1030N|ensembl:ENSG00000170458(gene)|ensembl:ENST00000302014(transcript)|ensembl:ENST00000401743(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001847"(opsonin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009408"(response to heat)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016019"(peptidoglycan immune receptor activity)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070891"(lipoteichoic acid binding)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071723"(lipopeptide binding)|go:"GO:0071726"(cellular response to diacyl bacterial lipopeptide)|go:"GO:0071727"(cellular response to triacyl bacterial lipopeptide)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR016337(Monocyte differentiation antigen CD14)|interpro:IPR032675|rcsb pdb:4GLP|reactome:R-HSA-1236974|reactome:R-HSA-140534|reactome:R-HSA-166016|reactome:R-HSA-166020|reactome:R-HSA-166058|reactome:R-HSA-166166|reactome:R-HSA-168179|reactome:R-HSA-168188|reactome:R-HSA-2562578|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-936964|reactome:R-HSA-937041|reactome:R-HSA-937072|reactome:R-HSA-975163|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)	go:"GO:0005576"(extracellular region)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR039670|rcsb pdb:1A9V|rcsb pdb:1KTJ|rcsb pdb:6OY4|dip:DIP-59729N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:MpfQfOF+t0EMlzBio2kyYeJU3hE9606	rogid:ANbwduc2K+FFtTYKEl5FSfwYkHw6956	rigid:Q0WhvBUIQk9cKDL+7sBFeGQNTAE	false	flag tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O95711	uniprotkb:Q9Y6Y9	intact:EBI-12203791|ensembl:ENSP00000230568|ensembl:ENSP00000369286|uniprotkb:Q9UQC4	intact:EBI-1539247|uniprotkb:E5RJJ7|uniprotkb:B3Y6A5|ensembl:ENSP00000284818	psi-mi:ly86_human(display_long)|uniprotkb:LY86(gene name)|psi-mi:LY86(display_short)|uniprotkb:MD1(gene name synonym)|uniprotkb:Protein MD-1(gene name synonym)	psi-mi:ly96_human(display_long)|uniprotkb:Protein MD-2(gene name synonym)|uniprotkb:ESOP-1(gene name synonym)|uniprotkb:LY96(gene name)|psi-mi:LY96(display_short)|uniprotkb:ESOP1(gene name synonym)|uniprotkb:MD2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Trompette et al. (2009)	pubmed:19060881|doi:10.1038/nature07548|imex:IM-17804	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15745128|imex:IM-17804-5|dip:DIP-189199E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000112799(gene)|ensembl:ENST00000230568(transcript)|ensembl:ENST00000379953(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0045087"(innate immune response)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR039945|rcsb pdb:3B2D|reactome:R-HSA-166016|refseq:NP_004262.1|dip:DIP-59105N	refseq:NP_001182726.1|refseq:NP_056179.3|dip:DIP-38571N|ensembl:ENSG00000154589(gene)|ensembl:ENST00000284818(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001875"(lipopolysaccharide immune receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0015026"(coreceptor activity)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032497"(detection of lipopolysaccharide)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR039217|rcsb pdb:1T2Z|rcsb pdb:2E56|rcsb pdb:2E59|rcsb pdb:2Z65|rcsb pdb:3FXI|rcsb pdb:3ULA|rcsb pdb:4G8A|reactome:R-HSA-1236974|reactome:R-HSA-140534|reactome:R-HSA-166016|reactome:R-HSA-166058|reactome:R-HSA-166166|reactome:R-HSA-2562578|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|reactome:R-HSA-936964|reactome:R-HSA-937041|reactome:R-HSA-937072|reactome:R-HSA-9707616|reactome:R-HSA-975163	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:Gx05aHaBStejBXQbs07QzrOU7zA9606	rogid:mudJbbtrzlBXQeXgJNpkEmKeH589606	rigid:ua3twgPWskfUoOw81F0bMqJePBs	false	ha tag:c-c	flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y6Y9	uniprotkb:P49278	intact:EBI-1539247|uniprotkb:E5RJJ7|uniprotkb:B3Y6A5|ensembl:ENSP00000284818	intact:EBI-15745025	psi-mi:ly96_human(display_long)|uniprotkb:Protein MD-2(gene name synonym)|uniprotkb:ESOP-1(gene name synonym)|uniprotkb:LY96(gene name)|psi-mi:LY96(display_short)|uniprotkb:ESOP1(gene name synonym)|uniprotkb:MD2(gene name synonym)	psi-mi:all2_derpt(display_long)|uniprotkb:DERP2(gene name)|psi-mi:DERP2(display_short)|uniprotkb:Allergen Der p II(gene name synonym)|uniprotkb:DPX(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Trompette et al. (2009)	pubmed:19060881|doi:10.1038/nature07548|imex:IM-17804	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:6956(derpt)|taxid:6956(Dermatophagoides pteronyssinus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15745149|imex:IM-17804-6|dip:DIP-189196E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001182726.1|refseq:NP_056179.3|dip:DIP-38571N|ensembl:ENSG00000154589(gene)|ensembl:ENST00000284818(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001875"(lipopolysaccharide immune receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0015026"(coreceptor activity)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032497"(detection of lipopolysaccharide)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR039217|rcsb pdb:1T2Z|rcsb pdb:2E56|rcsb pdb:2E59|rcsb pdb:2Z65|rcsb pdb:3FXI|rcsb pdb:3ULA|rcsb pdb:4G8A|reactome:R-HSA-1236974|reactome:R-HSA-140534|reactome:R-HSA-166016|reactome:R-HSA-166058|reactome:R-HSA-166166|reactome:R-HSA-2562578|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|reactome:R-HSA-936964|reactome:R-HSA-937041|reactome:R-HSA-937072|reactome:R-HSA-9707616|reactome:R-HSA-975163	go:"GO:0005576"(extracellular region)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR039670|rcsb pdb:1A9V|rcsb pdb:1KTJ|rcsb pdb:6OY4|dip:DIP-59729N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:mudJbbtrzlBXQeXgJNpkEmKeH589606	rogid:ANbwduc2K+FFtTYKEl5FSfwYkHw6956	rigid:JWc7T5NeEXpBe62fiX7nbYpgyQE	false	flag tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y6Y9	uniprotkb:O00206-1	intact:EBI-1539247|uniprotkb:E5RJJ7|uniprotkb:B3Y6A5|ensembl:ENSP00000284818	intact:EBI-15745059|ensembl:ENSP00000363089	psi-mi:ly96_human(display_long)|uniprotkb:Protein MD-2(gene name synonym)|uniprotkb:ESOP-1(gene name synonym)|uniprotkb:LY96(gene name)|psi-mi:LY96(display_short)|uniprotkb:ESOP1(gene name synonym)|uniprotkb:MD2(gene name synonym)	psi-mi:o00206-1(display_long)|uniprotkb:TLR4(gene name)|psi-mi:TLR4(display_short)|uniprotkb:hToll(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Trompette et al. (2009)	pubmed:19060881|doi:10.1038/nature07548|imex:IM-17804	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15745191|imex:IM-17804-8|dip:DIP-80758E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001182726.1|refseq:NP_056179.3|dip:DIP-38571N|ensembl:ENSG00000154589(gene)|ensembl:ENST00000284818(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001875"(lipopolysaccharide immune receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0015026"(coreceptor activity)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032497"(detection of lipopolysaccharide)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR039217|rcsb pdb:1T2Z|rcsb pdb:2E56|rcsb pdb:2E59|rcsb pdb:2Z65|rcsb pdb:3FXI|rcsb pdb:3ULA|rcsb pdb:4G8A|reactome:R-HSA-1236974|reactome:R-HSA-140534|reactome:R-HSA-166016|reactome:R-HSA-166058|reactome:R-HSA-166166|reactome:R-HSA-2562578|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|reactome:R-HSA-936964|reactome:R-HSA-937041|reactome:R-HSA-937072|reactome:R-HSA-9707616|reactome:R-HSA-975163	ensembl:ENSG00000136869(gene)|ensembl:ENST00000355622(transcript)|intact:EBI-528701(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:mudJbbtrzlBXQeXgJNpkEmKeH589606	rogid:4flqeyn60Q/64s8vQQHzlYDWz6w9606	rigid:TtiqaKkRZcA5phCW2towoXnQrdw	false	ha tag:c-c	yellow fluorescent protein tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00206-1	uniprotkb:P49278	intact:EBI-15745059|ensembl:ENSP00000363089	intact:EBI-15745025	psi-mi:o00206-1(display_long)|uniprotkb:TLR4(gene name)|psi-mi:TLR4(display_short)|uniprotkb:hToll(gene name synonym)	psi-mi:all2_derpt(display_long)|uniprotkb:DERP2(gene name)|psi-mi:DERP2(display_short)|uniprotkb:Allergen Der p II(gene name synonym)|uniprotkb:DPX(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Trompette et al. (2009)	pubmed:19060881|doi:10.1038/nature07548|imex:IM-17804	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:6956(derpt)|taxid:6956(Dermatophagoides pteronyssinus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15745170|imex:IM-17804-7|dip:DIP-189195E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000136869(gene)|ensembl:ENST00000355622(transcript)|intact:EBI-528701(isoform-parent)	go:"GO:0005576"(extracellular region)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR039670|rcsb pdb:1A9V|rcsb pdb:1KTJ|rcsb pdb:6OY4|dip:DIP-59729N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:4flqeyn60Q/64s8vQQHzlYDWz6w9606	rogid:ANbwduc2K+FFtTYKEl5FSfwYkHw6956	rigid:RVmgd8evU5BcgOtfdoPv5vgqrdw	false	yellow fluorescent protein tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00206-1	uniprotkb:P49278	intact:EBI-15745059|ensembl:ENSP00000363089	intact:EBI-15745025	psi-mi:o00206-1(display_long)|uniprotkb:TLR4(gene name)|psi-mi:TLR4(display_short)|uniprotkb:hToll(gene name synonym)	psi-mi:all2_derpt(display_long)|uniprotkb:DERP2(gene name)|psi-mi:DERP2(display_short)|uniprotkb:Allergen Der p II(gene name synonym)|uniprotkb:DPX(gene name synonym)	psi-mi:"MI:0096"(pull down)	Trompette et al. (2009)	pubmed:19060881|doi:10.1038/nature07548|imex:IM-17804	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:6956(derpt)|taxid:6956(Dermatophagoides pteronyssinus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15745212|imex:IM-17804-9|dip:DIP-189195E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000136869(gene)|ensembl:ENST00000355622(transcript)|intact:EBI-528701(isoform-parent)	go:"GO:0005576"(extracellular region)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR039670|rcsb pdb:1A9V|rcsb pdb:1KTJ|rcsb pdb:6OY4|dip:DIP-59729N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:4flqeyn60Q/64s8vQQHzlYDWz6w9606	rogid:ANbwduc2K+FFtTYKEl5FSfwYkHw6956	rigid:RVmgd8evU5BcgOtfdoPv5vgqrdw	false	fusion protein:c-c|binding-associated region:24-631	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)