#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P39935	uniprotkb:P10081	intact:EBI-9002|ensemblfungi:YGR162W|uniprotkb:D6VUU6	intact:EBI-9017|ensemblfungi:YKR059W|ensemblfungi:YJL138C|uniprotkb:D6VW46	psi-mi:if4f1_yeast(display_long)|uniprotkb:YGR162W(locus name)|uniprotkb:TIF4631(gene name)|psi-mi:TIF4631(display_short)|uniprotkb:eIF4G1(gene name synonym)|uniprotkb:mRNA cap-binding protein complex subunit p150(gene name synonym)	psi-mi:if4a_yeast(display_long)|uniprotkb:Stimulator factor I 37 kDa component(gene name synonym)|uniprotkb:TIF41A(gene name synonym)|uniprotkb:TIF41B(gene name synonym)|uniprotkb:Translation initiation factor 1/2(gene name synonym)|uniprotkb:J0660(orf name)|uniprotkb:YJL138C(locus name)|uniprotkb:YKR059W(locus name)|uniprotkb:TIF1(gene name)|psi-mi:TIF1(display_short)|uniprotkb:TIF2(gene name)|psi-mi:TIF2(display_short)|uniprotkb:Eukaryotic initiation factor 4A(gene name synonym)|uniprotkb:p37(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Schütz et al. (2008)	pubmed:18606994|doi:10.1073/pnas.0800418105|imex:IM-9401	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15713976|imex:IM-9401-1|dip:DIP-13926E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR162W(gene)|ensemblfungi:YGR162W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0034063"(stress granule assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|go:"GO:1902280"(regulation of RNA helicase activity)|rcsb pdb:2VSO|rcsb pdb:2VSX|rcsb pdb:6Z29|reactome:R-SCE-156827|reactome:R-SCE-166208|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702|reactome:R-SCE-975956|reactome:R-SCE-975957|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022745|interpro:IPR036211|rcsb pdb:1RF8|refseq:NP_011678.3|sgd:S000003394|mint:P39935|dip:DIP-985N	ensemblfungi:YJL138C(gene)|rcsb pdb:1QVA|rcsb pdb:2VSO|rcsb pdb:2VSX|reactome:R-SCE-156827|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702|rcsb pdb:1QDE|ensemblfungi:YJL138C_mRNA(transcript)|ensemblfungi:YKR059W(gene)|ensemblfungi:YKR059W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|rcsb pdb:1FUK|rcsb pdb:1FUU|refseq:NP_012985.3|refseq:NP_012397.1|sgd:S000001767|sgd:S000003674|mint:P10081|dip:DIP-4571N	psi-mi:"MI:0465"(dip)	crc64:391256802F86118E	crc64:19D8C133C815DD48	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:l5wtszbSL7dltfdiDAVe5zYnxVc559292	rogid:iEUvSBQzw5e9h9NnL8dTJCfbUqQ559292	rigid:ylm1y7JAdfjnS6ewyN9x4BXYgsE	false	binding-associated region:572-853	sufficient binding region:226-395	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39935	uniprotkb:P10081	intact:EBI-9002|ensemblfungi:YGR162W|uniprotkb:D6VUU6	intact:EBI-9017|ensemblfungi:YKR059W|ensemblfungi:YJL138C|uniprotkb:D6VW46	psi-mi:if4f1_yeast(display_long)|uniprotkb:YGR162W(locus name)|uniprotkb:TIF4631(gene name)|psi-mi:TIF4631(display_short)|uniprotkb:eIF4G1(gene name synonym)|uniprotkb:mRNA cap-binding protein complex subunit p150(gene name synonym)	psi-mi:if4a_yeast(display_long)|uniprotkb:Stimulator factor I 37 kDa component(gene name synonym)|uniprotkb:TIF41A(gene name synonym)|uniprotkb:TIF41B(gene name synonym)|uniprotkb:Translation initiation factor 1/2(gene name synonym)|uniprotkb:J0660(orf name)|uniprotkb:YJL138C(locus name)|uniprotkb:YKR059W(locus name)|uniprotkb:TIF1(gene name)|psi-mi:TIF1(display_short)|uniprotkb:TIF2(gene name)|psi-mi:TIF2(display_short)|uniprotkb:Eukaryotic initiation factor 4A(gene name synonym)|uniprotkb:p37(gene name synonym)	psi-mi:"MI:0096"(pull down)	Schütz et al. (2008)	pubmed:18606994|doi:10.1073/pnas.0800418105|imex:IM-9401	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15713997|imex:IM-9401-2|dip:DIP-13926E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR162W(gene)|ensemblfungi:YGR162W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0034063"(stress granule assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|go:"GO:1902280"(regulation of RNA helicase activity)|rcsb pdb:2VSO|rcsb pdb:2VSX|rcsb pdb:6Z29|reactome:R-SCE-156827|reactome:R-SCE-166208|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702|reactome:R-SCE-975956|reactome:R-SCE-975957|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022745|interpro:IPR036211|rcsb pdb:1RF8|refseq:NP_011678.3|sgd:S000003394|mint:P39935|dip:DIP-985N	ensemblfungi:YJL138C(gene)|rcsb pdb:1QVA|rcsb pdb:2VSO|rcsb pdb:2VSX|reactome:R-SCE-156827|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702|rcsb pdb:1QDE|ensemblfungi:YJL138C_mRNA(transcript)|ensemblfungi:YKR059W(gene)|ensemblfungi:YKR059W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|rcsb pdb:1FUK|rcsb pdb:1FUU|refseq:NP_012985.3|refseq:NP_012397.1|sgd:S000001767|sgd:S000003674|mint:P10081|dip:DIP-4571N	psi-mi:"MI:0465"(dip)	crc64:391256802F86118E	crc64:19D8C133C815DD48	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:l5wtszbSL7dltfdiDAVe5zYnxVc559292	rogid:iEUvSBQzw5e9h9NnL8dTJCfbUqQ559292	rigid:ylm1y7JAdfjnS6ewyN9x4BXYgsE	false	binding-associated region:572-853	sufficient binding region:226-395|his tag:n-n	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P39935	uniprotkb:P10081	intact:EBI-9002|ensemblfungi:YGR162W|uniprotkb:D6VUU6	intact:EBI-9017|ensemblfungi:YKR059W|ensemblfungi:YJL138C|uniprotkb:D6VW46	psi-mi:if4f1_yeast(display_long)|uniprotkb:YGR162W(locus name)|uniprotkb:TIF4631(gene name)|psi-mi:TIF4631(display_short)|uniprotkb:eIF4G1(gene name synonym)|uniprotkb:mRNA cap-binding protein complex subunit p150(gene name synonym)	psi-mi:if4a_yeast(display_long)|uniprotkb:Stimulator factor I 37 kDa component(gene name synonym)|uniprotkb:TIF41A(gene name synonym)|uniprotkb:TIF41B(gene name synonym)|uniprotkb:Translation initiation factor 1/2(gene name synonym)|uniprotkb:J0660(orf name)|uniprotkb:YJL138C(locus name)|uniprotkb:YKR059W(locus name)|uniprotkb:TIF1(gene name)|psi-mi:TIF1(display_short)|uniprotkb:TIF2(gene name)|psi-mi:TIF2(display_short)|uniprotkb:Eukaryotic initiation factor 4A(gene name synonym)|uniprotkb:p37(gene name synonym)	psi-mi:"MI:0038"(dynamic light scattering)	Schütz et al. (2008)	pubmed:18606994|doi:10.1073/pnas.0800418105|imex:IM-9401	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15714020|imex:IM-9401-3|dip:DIP-13926E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR162W(gene)|ensemblfungi:YGR162W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0034063"(stress granule assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|go:"GO:1902280"(regulation of RNA helicase activity)|rcsb pdb:2VSO|rcsb pdb:2VSX|rcsb pdb:6Z29|reactome:R-SCE-156827|reactome:R-SCE-166208|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702|reactome:R-SCE-975956|reactome:R-SCE-975957|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022745|interpro:IPR036211|rcsb pdb:1RF8|refseq:NP_011678.3|sgd:S000003394|mint:P39935|dip:DIP-985N	ensemblfungi:YJL138C(gene)|rcsb pdb:1QVA|rcsb pdb:2VSO|rcsb pdb:2VSX|reactome:R-SCE-156827|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702|rcsb pdb:1QDE|ensemblfungi:YJL138C_mRNA(transcript)|ensemblfungi:YKR059W(gene)|ensemblfungi:YKR059W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|rcsb pdb:1FUK|rcsb pdb:1FUU|refseq:NP_012985.3|refseq:NP_012397.1|sgd:S000001767|sgd:S000003674|mint:P10081|dip:DIP-4571N	psi-mi:"MI:0465"(dip)	crc64:391256802F86118E	crc64:19D8C133C815DD48	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:l5wtszbSL7dltfdiDAVe5zYnxVc559292	rogid:iEUvSBQzw5e9h9NnL8dTJCfbUqQ559292	rigid:ylm1y7JAdfjnS6ewyN9x4BXYgsE	false	binding-associated region:572-853	sufficient binding region:226-395	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39935	uniprotkb:P10081	intact:EBI-9002|ensemblfungi:YGR162W|uniprotkb:D6VUU6	intact:EBI-9017|ensemblfungi:YKR059W|ensemblfungi:YJL138C|uniprotkb:D6VW46	psi-mi:if4f1_yeast(display_long)|uniprotkb:YGR162W(locus name)|uniprotkb:TIF4631(gene name)|psi-mi:TIF4631(display_short)|uniprotkb:eIF4G1(gene name synonym)|uniprotkb:mRNA cap-binding protein complex subunit p150(gene name synonym)	psi-mi:if4a_yeast(display_long)|uniprotkb:Stimulator factor I 37 kDa component(gene name synonym)|uniprotkb:TIF41A(gene name synonym)|uniprotkb:TIF41B(gene name synonym)|uniprotkb:Translation initiation factor 1/2(gene name synonym)|uniprotkb:J0660(orf name)|uniprotkb:YJL138C(locus name)|uniprotkb:YKR059W(locus name)|uniprotkb:TIF1(gene name)|psi-mi:TIF1(display_short)|uniprotkb:TIF2(gene name)|psi-mi:TIF2(display_short)|uniprotkb:Eukaryotic initiation factor 4A(gene name synonym)|uniprotkb:p37(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Schütz et al. (2008)	pubmed:18606994|doi:10.1073/pnas.0800418105|imex:IM-9401	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15714043|dip:DIP-13926E|imex:IM-9401-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR162W(gene)|ensemblfungi:YGR162W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0034063"(stress granule assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|go:"GO:1902280"(regulation of RNA helicase activity)|rcsb pdb:2VSO|rcsb pdb:2VSX|rcsb pdb:6Z29|reactome:R-SCE-156827|reactome:R-SCE-166208|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702|reactome:R-SCE-975956|reactome:R-SCE-975957|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022745|interpro:IPR036211|rcsb pdb:1RF8|refseq:NP_011678.3|sgd:S000003394|mint:P39935|dip:DIP-985N	ensemblfungi:YJL138C(gene)|rcsb pdb:1QVA|rcsb pdb:2VSO|rcsb pdb:2VSX|reactome:R-SCE-156827|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702|rcsb pdb:1QDE|ensemblfungi:YJL138C_mRNA(transcript)|ensemblfungi:YKR059W(gene)|ensemblfungi:YKR059W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|rcsb pdb:1FUK|rcsb pdb:1FUU|refseq:NP_012985.3|refseq:NP_012397.1|sgd:S000001767|sgd:S000003674|mint:P10081|dip:DIP-4571N	psi-mi:"MI:0465"(dip)	crc64:391256802F86118E	crc64:19D8C133C815DD48	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:l5wtszbSL7dltfdiDAVe5zYnxVc559292	rogid:iEUvSBQzw5e9h9NnL8dTJCfbUqQ559292	rigid:ylm1y7JAdfjnS6ewyN9x4BXYgsE	false	binding-associated region:572-853	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04637-1	uniprotkb:P60842	intact:EBI-5456295|ensembl:ENSP00000316879	intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831	psi-mi:q04637-1(display_long)|uniprotkb:EIF4G1(gene name)|psi-mi:EIF4G1(display_short)|uniprotkb:EIF4F(gene name synonym)|uniprotkb:EIF4G(gene name synonym)|uniprotkb:EIF4GI(gene name synonym)|uniprotkb:p220(gene name synonym)	psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Schütz et al. (2008)	pubmed:18606994|doi:10.1073/pnas.0800418105|imex:IM-9401	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15714062|dip:DIP-87975E|imex:IM-9401-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-73711(isoform-parent)|ensembl:ENSG00000114867(gene)|ensembl:ENST00000346169(transcript)	refseq:NP_001407.1|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960(gene)|ensembl:ENST00000293831(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:0UfVxxWOLUvrvFfcteeTc2RrbhA9606	rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606	rigid:vSQVYLhz9nbsNODPN2tfkElLH+Q	false	sufficient binding region:710-970	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04637-1	uniprotkb:P60842	intact:EBI-5456295|ensembl:ENSP00000316879	intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831	psi-mi:q04637-1(display_long)|uniprotkb:EIF4G1(gene name)|psi-mi:EIF4G1(display_short)|uniprotkb:EIF4F(gene name synonym)|uniprotkb:EIF4G(gene name synonym)|uniprotkb:EIF4GI(gene name synonym)|uniprotkb:p220(gene name synonym)	psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym)	psi-mi:"MI:0038"(dynamic light scattering)	Schütz et al. (2008)	pubmed:18606994|doi:10.1073/pnas.0800418105|imex:IM-9401	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15714081|dip:DIP-87975E|imex:IM-9401-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-73711(isoform-parent)|ensembl:ENSG00000114867(gene)|ensembl:ENST00000346169(transcript)	refseq:NP_001407.1|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960(gene)|ensembl:ENST00000293831(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:0UfVxxWOLUvrvFfcteeTc2RrbhA9606	rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606	rigid:vSQVYLhz9nbsNODPN2tfkElLH+Q	false	sufficient binding region:710-970	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04637	uniprotkb:P60842	intact:EBI-73711|uniprotkb:O43177|uniprotkb:O95066|uniprotkb:Q5HYG0|uniprotkb:Q6ZN21|uniprotkb:Q8N102|intact:EBI-11020102|uniprotkb:D3DNT4|uniprotkb:D3DNT5|uniprotkb:D3DNT2|uniprotkb:E9PFM1|uniprotkb:G5E9S1|intact:EBI-28974642|ensembl:ENSP00000316879	intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831	psi-mi:if4g1_human(display_long)|uniprotkb:p220(gene name synonym)|uniprotkb:EIF4G1(gene name)|psi-mi:EIF4G1(display_short)|uniprotkb:EIF4G(gene name synonym)|uniprotkb:EIF4GI(gene name synonym)|uniprotkb:EIF4F(gene name synonym)	psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Schütz et al. (2008)	pubmed:18606994|doi:10.1073/pnas.0800418105|imex:IM-9401	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15714100|dip:DIP-60493E|imex:IM-9401-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000342981|ensembl:ENSP00000343450|ensembl:ENSP00000316879|ensembl:ENST00000350481|ensembl:ENSP00000317600|ensembl:ENST00000352767|ensembl:ENSP00000338020|ensembl:ENST00000382330|ensembl:ENSP00000371767|ensembl:ENST00000392537|ensembl:ENSP00000376320|ensembl:ENST00000414031|ensembl:ENSP00000391935|ensembl:ENST00000424196|ensembl:ENSP00000416255|ensembl:ENST00000434061|ensembl:ENSP00000411826|refseq:NP_886553.3|refseq:NP_937884.1|refseq:NP_937885.1|refseq:NP_004944.3|dip:DIP-1161N|ensembl:ENSG00000114867(gene)|ensembl:ENST00000346169(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032502"(developmental process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097009"(energy homeostasis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905537"(positive regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905612"(positive regulation of mRNA cap binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1905696"(regulation of polysome binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037584|mint:Q04637|rcsb pdb:1LJ2|rcsb pdb:1UG3|rcsb pdb:2W97|rcsb pdb:4AZA|rcsb pdb:4F02|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5T46|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957	refseq:NP_001407.1|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960(gene)|ensembl:ENST00000293831(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706	psi-mi:"MI:0465"(dip)	-	-	dip-version:1|dip-updated-by:nodeMerge04|dip-date-update:2013-08-04|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:0UfVxxWOLUvrvFfcteeTc2RrbhA9606	rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606	rigid:vSQVYLhz9nbsNODPN2tfkElLH+Q	false	sufficient binding region:710-970	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04637	uniprotkb:P60842	intact:EBI-73711|uniprotkb:O43177|uniprotkb:O95066|uniprotkb:Q5HYG0|uniprotkb:Q6ZN21|uniprotkb:Q8N102|intact:EBI-11020102|uniprotkb:D3DNT4|uniprotkb:D3DNT5|uniprotkb:D3DNT2|uniprotkb:E9PFM1|uniprotkb:G5E9S1|intact:EBI-28974642|ensembl:ENSP00000316879	intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831	psi-mi:if4g1_human(display_long)|uniprotkb:p220(gene name synonym)|uniprotkb:EIF4G1(gene name)|psi-mi:EIF4G1(display_short)|uniprotkb:EIF4G(gene name synonym)|uniprotkb:EIF4GI(gene name synonym)|uniprotkb:EIF4F(gene name synonym)	psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym)	psi-mi:"MI:0038"(dynamic light scattering)	Schütz et al. (2008)	pubmed:18606994|doi:10.1073/pnas.0800418105|imex:IM-9401	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15714122|dip:DIP-60493E|imex:IM-9401-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000342981|ensembl:ENSP00000343450|ensembl:ENSP00000316879|ensembl:ENST00000350481|ensembl:ENSP00000317600|ensembl:ENST00000352767|ensembl:ENSP00000338020|ensembl:ENST00000382330|ensembl:ENSP00000371767|ensembl:ENST00000392537|ensembl:ENSP00000376320|ensembl:ENST00000414031|ensembl:ENSP00000391935|ensembl:ENST00000424196|ensembl:ENSP00000416255|ensembl:ENST00000434061|ensembl:ENSP00000411826|refseq:NP_886553.3|refseq:NP_937884.1|refseq:NP_937885.1|refseq:NP_004944.3|dip:DIP-1161N|ensembl:ENSG00000114867(gene)|ensembl:ENST00000346169(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032502"(developmental process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097009"(energy homeostasis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905537"(positive regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905612"(positive regulation of mRNA cap binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1905696"(regulation of polysome binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037584|mint:Q04637|rcsb pdb:1LJ2|rcsb pdb:1UG3|rcsb pdb:2W97|rcsb pdb:4AZA|rcsb pdb:4F02|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5T46|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957	refseq:NP_001407.1|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960(gene)|ensembl:ENST00000293831(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706	psi-mi:"MI:0465"(dip)	-	-	dip-version:1|dip-updated-by:nodeMerge04|dip-date-update:2013-08-04|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:0UfVxxWOLUvrvFfcteeTc2RrbhA9606	rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606	rigid:vSQVYLhz9nbsNODPN2tfkElLH+Q	false	sufficient binding region:710-970	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)