#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P29033 uniprotkb:P29033 intact:EBI-3905204|uniprotkb:Q5YLL1|uniprotkb:Q508A6|uniprotkb:Q9NNY4|uniprotkb:Q9H536|uniprotkb:Q96AK0|uniprotkb:Q5YLL4|uniprotkb:Q6IPV5|uniprotkb:Q86U88|uniprotkb:Q5YLL0|uniprotkb:Q508A5|ensembl:ENSP00000372295|ensembl:ENSP00000372299 intact:EBI-3905204|uniprotkb:Q5YLL1|uniprotkb:Q508A6|uniprotkb:Q9NNY4|uniprotkb:Q9H536|uniprotkb:Q96AK0|uniprotkb:Q5YLL4|uniprotkb:Q6IPV5|uniprotkb:Q86U88|uniprotkb:Q5YLL0|uniprotkb:Q508A5|ensembl:ENSP00000372295|ensembl:ENSP00000372299 psi-mi:cxb2_human(display_long)|uniprotkb:GJB2(gene name)|psi-mi:GJB2(display_short)|uniprotkb:Connexin-26(gene name synonym) psi-mi:cxb2_human(display_long)|uniprotkb:GJB2(gene name)|psi-mi:GJB2(display_short)|uniprotkb:Connexin-26(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Oshima et al. (2007) pubmed:17551008|doi:10.1073/pnas.0703704104|imex:IM-22857 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15641311|imex:IM-22857-1|dip:DIP-189247E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011533351.1|refseq:NP_003995.2|dip:DIP-59742N|ensembl:ENSG00000165474(gene)|ensembl:ENST00000382844(transcript)|ensembl:ENST00000382848(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007568"(aging)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046697"(decidualization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048839"(inner ear development)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|go:"GO:1905867"(epididymis development)|go:"GO:1990349"(gap junction-mediated intercellular transport)|interpro:IPR000500(Connexins)|interpro:IPR002268("Gap junction beta-2 protein (Cx26)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR017990|interpro:IPR019570|interpro:IPR038359|rcsb pdb:1XIR|rcsb pdb:2ZW3|rcsb pdb:3IZ1|rcsb pdb:3IZ2|rcsb pdb:5ER7|rcsb pdb:5ERA|rcsb pdb:5KJ3|rcsb pdb:5KJG|rcsb pdb:6UVR|rcsb pdb:6UVS|rcsb pdb:6UVT|reactome:R-HSA-190704|reactome:R-HSA-190827|reactome:R-HSA-190861|reactome:R-HSA-190872 refseq:XP_011533351.1|refseq:NP_003995.2|dip:DIP-59742N|ensembl:ENSG00000165474(gene)|ensembl:ENST00000382844(transcript)|ensembl:ENST00000382848(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007568"(aging)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046697"(decidualization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048839"(inner ear development)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|go:"GO:1905867"(epididymis development)|go:"GO:1990349"(gap junction-mediated intercellular transport)|interpro:IPR000500(Connexins)|interpro:IPR002268("Gap junction beta-2 protein (Cx26)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR017990|interpro:IPR019570|interpro:IPR038359|rcsb pdb:1XIR|rcsb pdb:2ZW3|rcsb pdb:3IZ1|rcsb pdb:3IZ2|rcsb pdb:5ER7|rcsb pdb:5ERA|rcsb pdb:5KJ3|rcsb pdb:5KJG|rcsb pdb:6UVR|rcsb pdb:6UVS|rcsb pdb:6UVT|reactome:R-HSA-190704|reactome:R-HSA-190827|reactome:R-HSA-190861|reactome:R-HSA-190872 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)") - 2017/08/05 2017/08/10 rogid:Hzvw5T/Ve5Fx4kbacVbxArww2ns9606 rogid:Hzvw5T/Ve5Fx4kbacVbxArww2ns9606 rigid:3+sA1tIQQdbq77dqToiDPgrJEtk false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29033 uniprotkb:P29033 intact:EBI-3905204|uniprotkb:Q5YLL1|uniprotkb:Q508A6|uniprotkb:Q9NNY4|uniprotkb:Q9H536|uniprotkb:Q96AK0|uniprotkb:Q5YLL4|uniprotkb:Q6IPV5|uniprotkb:Q86U88|uniprotkb:Q5YLL0|uniprotkb:Q508A5|ensembl:ENSP00000372295|ensembl:ENSP00000372299 intact:EBI-3905204|uniprotkb:Q5YLL1|uniprotkb:Q508A6|uniprotkb:Q9NNY4|uniprotkb:Q9H536|uniprotkb:Q96AK0|uniprotkb:Q5YLL4|uniprotkb:Q6IPV5|uniprotkb:Q86U88|uniprotkb:Q5YLL0|uniprotkb:Q508A5|ensembl:ENSP00000372295|ensembl:ENSP00000372299 psi-mi:cxb2_human(display_long)|uniprotkb:GJB2(gene name)|psi-mi:GJB2(display_short)|uniprotkb:Connexin-26(gene name synonym) psi-mi:cxb2_human(display_long)|uniprotkb:GJB2(gene name)|psi-mi:GJB2(display_short)|uniprotkb:Connexin-26(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Oshima et al. (2007) pubmed:17551008|doi:10.1073/pnas.0703704104|imex:IM-22857 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15641327|imex:IM-22857-2|dip:DIP-189247E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011533351.1|refseq:NP_003995.2|dip:DIP-59742N|ensembl:ENSG00000165474(gene)|ensembl:ENST00000382844(transcript)|ensembl:ENST00000382848(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007568"(aging)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046697"(decidualization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048839"(inner ear development)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|go:"GO:1905867"(epididymis development)|go:"GO:1990349"(gap junction-mediated intercellular transport)|interpro:IPR000500(Connexins)|interpro:IPR002268("Gap junction beta-2 protein (Cx26)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR017990|interpro:IPR019570|interpro:IPR038359|rcsb pdb:1XIR|rcsb pdb:2ZW3|rcsb pdb:3IZ1|rcsb pdb:3IZ2|rcsb pdb:5ER7|rcsb pdb:5ERA|rcsb pdb:5KJ3|rcsb pdb:5KJG|rcsb pdb:6UVR|rcsb pdb:6UVS|rcsb pdb:6UVT|reactome:R-HSA-190704|reactome:R-HSA-190827|reactome:R-HSA-190861|reactome:R-HSA-190872 refseq:XP_011533351.1|refseq:NP_003995.2|dip:DIP-59742N|ensembl:ENSG00000165474(gene)|ensembl:ENST00000382844(transcript)|ensembl:ENST00000382848(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007568"(aging)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046697"(decidualization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048839"(inner ear development)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|go:"GO:1905867"(epididymis development)|go:"GO:1990349"(gap junction-mediated intercellular transport)|interpro:IPR000500(Connexins)|interpro:IPR002268("Gap junction beta-2 protein (Cx26)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR017990|interpro:IPR019570|interpro:IPR038359|rcsb pdb:1XIR|rcsb pdb:2ZW3|rcsb pdb:3IZ1|rcsb pdb:3IZ2|rcsb pdb:5ER7|rcsb pdb:5ERA|rcsb pdb:5KJ3|rcsb pdb:5KJG|rcsb pdb:6UVR|rcsb pdb:6UVS|rcsb pdb:6UVT|reactome:R-HSA-190704|reactome:R-HSA-190827|reactome:R-HSA-190861|reactome:R-HSA-190872 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)") - 2017/08/05 2017/08/10 rogid:Hzvw5T/Ve5Fx4kbacVbxArww2ns9606 rogid:Hzvw5T/Ve5Fx4kbacVbxArww2ns9606 rigid:3+sA1tIQQdbq77dqToiDPgrJEtk false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)