#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q61115	uniprotkb:Q96EY1	intact:EBI-15619523|ensembl:ENSMUSP00000021921	intact:EBI-356767|uniprotkb:O75472|uniprotkb:Q8WUJ6|uniprotkb:Q8WXJ3|uniprotkb:Q96D76|uniprotkb:Q96IV1|uniprotkb:Q9NYH8|uniprotkb:B2RAJ5|uniprotkb:B4DI33|uniprotkb:E7ES32|ensembl:ENSP00000262375|ensembl:ENSP00000477570	psi-mi:ptc1_mouse(display_long)|uniprotkb:Ptch1(gene name)|psi-mi:Ptch1(display_short)|uniprotkb:Ptch(gene name synonym)	psi-mi:dnja3_human(display_long)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)|uniprotkb:TID1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wakabayashi et al. (2007)	pubmed:17230190|doi:10.1038/nature05489|imex:IM-21194	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15619621|imex:IM-21194-1|dip:DIP-191092E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001709"(cell fate determination)|go:"GO:0001841"(neural tube formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005929"(cilium)|go:"GO:0007165"(signal transduction)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007389"(pattern specification process)|go:"GO:0007420"(brain development)|go:"GO:0008158"(hedgehog receptor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008544"(epidermis development)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010157"(response to chlorate)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016485"(protein processing)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0021997"(neural plate axis specification)|go:"GO:0030326"(embryonic limb morphogenesis)|ensembl:ENSMUSG00000021466(gene)|go:"GO:0030332"(cyclin binding)|go:"GO:0030496"(midbody)|go:"GO:0030850"(prostate gland development)|go:"GO:0030879"(mammary gland development)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0040008"(regulation of growth)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|ensembl:ENSMUST00000021921(transcript)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0045177"(apical part of cell)|go:"GO:0045606"(positive regulation of epidermal cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061005"(cell differentiation involved in kidney development)|go:"GO:0061053"(somite development)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0072203"(cell proliferation involved in metanephros development)|go:"GO:0072205"(metanephric collecting duct development)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097108"(hedgehog family protein binding)|go:"GO:0097421"(liver regeneration)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|interpro:IPR004766(Transmembrane receptor, patched)|rcsb pdb:6MG8|rcsb pdb:7DZP|rcsb pdb:7DZQ|rcsb pdb:7K65|reactome:R-MMU-5610787|reactome:R-MMU-5632681|reactome:R-MMU-5632684|reactome:R-MMU-5635838|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_032983.1|refseq:XP_006517222.1|dip:DIP-60268N	refseq:NP_001273445.1|refseq:NP_001128582.1|refseq:NP_005138.3|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0106137"(IkappaB kinase complex binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|mint:Q96EY1|rcsb pdb:2CTT|rcsb pdb:2DN9|rcsb pdb:6IWS|ensembl:ENSG00000103423(gene)|ensembl:ENSG00000276726(gene)|ensembl:ENST00000262375(transcript)|ensembl:ENST00000612103(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005133"(interferon-gamma receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007569"(cell aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|dip:DIP-33870N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:0sOlsCQpq6LNo56MPu1WFXRyWZ810090	rogid:WnRYdQ9E3yGbSlq1SSGTX9k+3uA9606	rigid:5PWA1krWQ48G7p1fP3MepqS52PY	false	ha tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q61115	uniprotkb:Q96EY1	intact:EBI-15619523|ensembl:ENSMUSP00000021921	intact:EBI-356767|uniprotkb:O75472|uniprotkb:Q8WUJ6|uniprotkb:Q8WXJ3|uniprotkb:Q96D76|uniprotkb:Q96IV1|uniprotkb:Q9NYH8|uniprotkb:B2RAJ5|uniprotkb:B4DI33|uniprotkb:E7ES32|ensembl:ENSP00000262375|ensembl:ENSP00000477570	psi-mi:ptc1_mouse(display_long)|uniprotkb:Ptch1(gene name)|psi-mi:Ptch1(display_short)|uniprotkb:Ptch(gene name synonym)	psi-mi:dnja3_human(display_long)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)|uniprotkb:TID1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wakabayashi et al. (2007)	pubmed:17230190|doi:10.1038/nature05489|imex:IM-21194	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15619640|imex:IM-21194-2|dip:DIP-191092E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001709"(cell fate determination)|go:"GO:0001841"(neural tube formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005929"(cilium)|go:"GO:0007165"(signal transduction)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007389"(pattern specification process)|go:"GO:0007420"(brain development)|go:"GO:0008158"(hedgehog receptor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008544"(epidermis development)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010157"(response to chlorate)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016485"(protein processing)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0021997"(neural plate axis specification)|go:"GO:0030326"(embryonic limb morphogenesis)|ensembl:ENSMUSG00000021466(gene)|go:"GO:0030332"(cyclin binding)|go:"GO:0030496"(midbody)|go:"GO:0030850"(prostate gland development)|go:"GO:0030879"(mammary gland development)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0040008"(regulation of growth)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|ensembl:ENSMUST00000021921(transcript)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0045177"(apical part of cell)|go:"GO:0045606"(positive regulation of epidermal cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061005"(cell differentiation involved in kidney development)|go:"GO:0061053"(somite development)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0072203"(cell proliferation involved in metanephros development)|go:"GO:0072205"(metanephric collecting duct development)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097108"(hedgehog family protein binding)|go:"GO:0097421"(liver regeneration)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|interpro:IPR004766(Transmembrane receptor, patched)|rcsb pdb:6MG8|rcsb pdb:7DZP|rcsb pdb:7DZQ|rcsb pdb:7K65|reactome:R-MMU-5610787|reactome:R-MMU-5632681|reactome:R-MMU-5632684|reactome:R-MMU-5635838|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_032983.1|refseq:XP_006517222.1|dip:DIP-60268N	refseq:NP_001273445.1|refseq:NP_001128582.1|refseq:NP_005138.3|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0106137"(IkappaB kinase complex binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|mint:Q96EY1|rcsb pdb:2CTT|rcsb pdb:2DN9|rcsb pdb:6IWS|ensembl:ENSG00000103423(gene)|ensembl:ENSG00000276726(gene)|ensembl:ENST00000262375(transcript)|ensembl:ENST00000612103(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005133"(interferon-gamma receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007569"(cell aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|dip:DIP-33870N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:0sOlsCQpq6LNo56MPu1WFXRyWZ810090	rogid:WnRYdQ9E3yGbSlq1SSGTX9k+3uA9606	rigid:5PWA1krWQ48G7p1fP3MepqS52PY	false	ha tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)