#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P55085	uniprotkb:P13726	intact:EBI-4303189|uniprotkb:Q13317|uniprotkb:Q13346|ensembl:ENSP00000296677|uniprotkb:Q53XJ8	intact:EBI-1040727|uniprotkb:Q6FHG2|uniprotkb:Q86WH4|uniprotkb:D3DT47|ensembl:ENSP00000334145	psi-mi:par2_human(display_long)|uniprotkb:F2RL1(gene name)|psi-mi:F2RL1(display_short)|uniprotkb:GPR11(gene name synonym)|uniprotkb:PAR2(gene name synonym)|uniprotkb:Coagulation factor II receptor-like 1(gene name synonym)|uniprotkb:G-protein coupled receptor 11(gene name synonym)|uniprotkb:Thrombin receptor-like 1(gene name synonym)	psi-mi:tf_human(display_long)|uniprotkb:F3(gene name)|psi-mi:F3(display_short)|uniprotkb:Coagulation factor III(gene name synonym)|uniprotkb:Thromboplastin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ahamed et al. (2006)	pubmed:16959886|doi:10.1073/pnas.0606411103|imex:IM-23904	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15599653|imex:IM-23904-1|dip:DIP-198058E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005233.3|ensembl:ENSG00000164251(gene)|ensembl:ENST00000296677(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002690"(positive regulation of leukocyte chemotaxis)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007596"(blood coagulation)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015057"(thrombin-activated receptor activity)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0031143"(pseudopodium)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034140"(negative regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042119"(neutrophil activation)|go:"GO:0042311"(vasodilation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043311"(positive regulation of eosinophil degranulation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045217"(cell-cell junction maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070661"(leukocyte proliferation)|go:"GO:0070963"(positive regulation of neutrophil mediated killing of gram-negative bacterium)|go:"GO:0097029"(mature conventional dendritic cell differentiation)|go:"GO:1900135"(positive regulation of renin secretion into blood stream)|go:"GO:2000341"("regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002281(Protease-activated receptor 2)|interpro:IPR003912(Protease-activated receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P55085|rcsb pdb:5NDD|rcsb pdb:5NDZ|rcsb pdb:5NJ6|reactome:R-HSA-375276|reactome:R-HSA-416476|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032722"(positive regulation of chemokine production)|dip:DIP-42044N	refseq:NP_001984.1|refseq:NP_001171567.1|ensembl:ENSG00000117525(gene)|ensembl:ENST00000334047(transcript)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002541"(activation of plasma proteins involved in acute inflammatory response)|go:"GO:0002543"(activation of blood coagulation via clotting cascade)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010641"(positive regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031233"(intrinsic component of external side of plasma membrane)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:1905286"(serine-type peptidase complex)|interpro:IPR001187(Tissue factor)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015373(Interferon-alpha/beta receptor, fibronectin type III)|interpro:IPR030472|interpro:IPR036116|rcsb pdb:1AHW|rcsb pdb:1BOY|rcsb pdb:1DAN|rcsb pdb:1FAK|rcsb pdb:1J9C|rcsb pdb:1JPS|rcsb pdb:1NL8|rcsb pdb:1O5D|rcsb pdb:1UJ3|rcsb pdb:1W0Y|rcsb pdb:1W2K|rcsb pdb:1WQV|rcsb pdb:1WSS|rcsb pdb:1WTG|rcsb pdb:1WUN|rcsb pdb:1WV7|rcsb pdb:1Z6J|rcsb pdb:2A2Q|rcsb pdb:2AEI|rcsb pdb:2AER|rcsb pdb:2B7D|rcsb pdb:2B8O|rcsb pdb:2C4F|rcsb pdb:2CEF|rcsb pdb:2CEH|rcsb pdb:2CEZ|rcsb pdb:2CFJ|rcsb pdb:2EC9|rcsb pdb:2F9B|rcsb pdb:2FIR|rcsb pdb:2FLB|rcsb pdb:2FLR|rcsb pdb:2HFT|rcsb pdb:2PUQ|rcsb pdb:2ZP0|rcsb pdb:2ZWL|rcsb pdb:2ZZU|rcsb pdb:3ELA|rcsb pdb:3TH2|rcsb pdb:3TH3|rcsb pdb:3TH4|rcsb pdb:4IBL|rcsb pdb:4M7L|rcsb pdb:4YLQ|rcsb pdb:4Z6A|rcsb pdb:4ZMA|rcsb pdb:5W06|rcsb pdb:6R2W|reactome:R-HSA-140834|reactome:R-HSA-9031628|rcsb pdb:1TFH|dip:DIP-6136N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:j9cMnyj9C74tReGYkQvGFy+cez49606	rogid:/9cwpvhO2XibmA8HkQaSLRfA6689606	rigid:tnGcN8qPd2A4P3zMEMvHKhDWlqE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P55085	uniprotkb:P13726	intact:EBI-4303189|uniprotkb:Q13317|uniprotkb:Q13346|ensembl:ENSP00000296677|uniprotkb:Q53XJ8	intact:EBI-1040727|uniprotkb:Q6FHG2|uniprotkb:Q86WH4|uniprotkb:D3DT47|ensembl:ENSP00000334145	psi-mi:par2_human(display_long)|uniprotkb:F2RL1(gene name)|psi-mi:F2RL1(display_short)|uniprotkb:GPR11(gene name synonym)|uniprotkb:PAR2(gene name synonym)|uniprotkb:Coagulation factor II receptor-like 1(gene name synonym)|uniprotkb:G-protein coupled receptor 11(gene name synonym)|uniprotkb:Thrombin receptor-like 1(gene name synonym)	psi-mi:tf_human(display_long)|uniprotkb:F3(gene name)|psi-mi:F3(display_short)|uniprotkb:Coagulation factor III(gene name synonym)|uniprotkb:Thromboplastin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ahamed et al. (2006)	pubmed:16959886|doi:10.1073/pnas.0606411103|imex:IM-23904	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15599670|imex:IM-23904-2|dip:DIP-198058E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005233.3|ensembl:ENSG00000164251(gene)|ensembl:ENST00000296677(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002690"(positive regulation of leukocyte chemotaxis)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007596"(blood coagulation)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015057"(thrombin-activated receptor activity)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0031143"(pseudopodium)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034140"(negative regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042119"(neutrophil activation)|go:"GO:0042311"(vasodilation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043311"(positive regulation of eosinophil degranulation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045217"(cell-cell junction maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070661"(leukocyte proliferation)|go:"GO:0070963"(positive regulation of neutrophil mediated killing of gram-negative bacterium)|go:"GO:0097029"(mature conventional dendritic cell differentiation)|go:"GO:1900135"(positive regulation of renin secretion into blood stream)|go:"GO:2000341"("regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002281(Protease-activated receptor 2)|interpro:IPR003912(Protease-activated receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P55085|rcsb pdb:5NDD|rcsb pdb:5NDZ|rcsb pdb:5NJ6|reactome:R-HSA-375276|reactome:R-HSA-416476|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032722"(positive regulation of chemokine production)|dip:DIP-42044N	refseq:NP_001984.1|refseq:NP_001171567.1|ensembl:ENSG00000117525(gene)|ensembl:ENST00000334047(transcript)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002541"(activation of plasma proteins involved in acute inflammatory response)|go:"GO:0002543"(activation of blood coagulation via clotting cascade)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010641"(positive regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031233"(intrinsic component of external side of plasma membrane)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:1905286"(serine-type peptidase complex)|interpro:IPR001187(Tissue factor)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015373(Interferon-alpha/beta receptor, fibronectin type III)|interpro:IPR030472|interpro:IPR036116|rcsb pdb:1AHW|rcsb pdb:1BOY|rcsb pdb:1DAN|rcsb pdb:1FAK|rcsb pdb:1J9C|rcsb pdb:1JPS|rcsb pdb:1NL8|rcsb pdb:1O5D|rcsb pdb:1UJ3|rcsb pdb:1W0Y|rcsb pdb:1W2K|rcsb pdb:1WQV|rcsb pdb:1WSS|rcsb pdb:1WTG|rcsb pdb:1WUN|rcsb pdb:1WV7|rcsb pdb:1Z6J|rcsb pdb:2A2Q|rcsb pdb:2AEI|rcsb pdb:2AER|rcsb pdb:2B7D|rcsb pdb:2B8O|rcsb pdb:2C4F|rcsb pdb:2CEF|rcsb pdb:2CEH|rcsb pdb:2CEZ|rcsb pdb:2CFJ|rcsb pdb:2EC9|rcsb pdb:2F9B|rcsb pdb:2FIR|rcsb pdb:2FLB|rcsb pdb:2FLR|rcsb pdb:2HFT|rcsb pdb:2PUQ|rcsb pdb:2ZP0|rcsb pdb:2ZWL|rcsb pdb:2ZZU|rcsb pdb:3ELA|rcsb pdb:3TH2|rcsb pdb:3TH3|rcsb pdb:3TH4|rcsb pdb:4IBL|rcsb pdb:4M7L|rcsb pdb:4YLQ|rcsb pdb:4Z6A|rcsb pdb:4ZMA|rcsb pdb:5W06|rcsb pdb:6R2W|reactome:R-HSA-140834|reactome:R-HSA-9031628|rcsb pdb:1TFH|dip:DIP-6136N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:j9cMnyj9C74tReGYkQvGFy+cez49606	rogid:/9cwpvhO2XibmA8HkQaSLRfA6689606	rigid:tnGcN8qPd2A4P3zMEMvHKhDWlqE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P07237	uniprotkb:P13726	intact:EBI-395883|uniprotkb:P30037|uniprotkb:P32079|uniprotkb:Q15205|uniprotkb:Q6LDE5|uniprotkb:B2RDQ2|ensembl:ENSP00000327801	intact:EBI-1040727|uniprotkb:Q6FHG2|uniprotkb:Q86WH4|uniprotkb:D3DT47|ensembl:ENSP00000334145	psi-mi:pdia1_human(display_long)|uniprotkb:P4HB(gene name)|psi-mi:P4HB(display_short)|uniprotkb:PDI(gene name synonym)|uniprotkb:PDIA1(gene name synonym)|uniprotkb:PO4DB(gene name synonym)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:p55(gene name synonym)|uniprotkb:ERBA2L(gene name synonym)	psi-mi:tf_human(display_long)|uniprotkb:F3(gene name)|psi-mi:F3(display_short)|uniprotkb:Coagulation factor III(gene name synonym)|uniprotkb:Thromboplastin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ahamed et al. (2006)	pubmed:16959886|doi:10.1073/pnas.0606411103|imex:IM-23904	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15599687|imex:IM-23904-3|dip:DIP-198059E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000909.2|ensembl:ENSG00000185624(gene)|ensembl:ENST00000331483(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0038155"(interleukin-23-mediated signaling pathway)|go:"GO:0042470"(melanosome)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P07237|rcsb pdb:1BJX|rcsb pdb:1MEK|rcsb pdb:1X5C|rcsb pdb:2BJX|rcsb pdb:2K18|rcsb pdb:3BJ5|rcsb pdb:3UEM|rcsb pdb:4EKZ|rcsb pdb:4EL1|rcsb pdb:4JU5|rcsb pdb:6I7S|reactome:R-HSA-1650814|reactome:R-HSA-3299685|reactome:R-HSA-381426|reactome:R-HSA-5358346|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-9020591|reactome:R-HSA-9020933|dip:DIP-32979N	refseq:NP_001984.1|refseq:NP_001171567.1|ensembl:ENSG00000117525(gene)|ensembl:ENST00000334047(transcript)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002541"(activation of plasma proteins involved in acute inflammatory response)|go:"GO:0002543"(activation of blood coagulation via clotting cascade)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010641"(positive regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031233"(intrinsic component of external side of plasma membrane)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:1905286"(serine-type peptidase complex)|interpro:IPR001187(Tissue factor)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015373(Interferon-alpha/beta receptor, fibronectin type III)|interpro:IPR030472|interpro:IPR036116|rcsb pdb:1AHW|rcsb pdb:1BOY|rcsb pdb:1DAN|rcsb pdb:1FAK|rcsb pdb:1J9C|rcsb pdb:1JPS|rcsb pdb:1NL8|rcsb pdb:1O5D|rcsb pdb:1UJ3|rcsb pdb:1W0Y|rcsb pdb:1W2K|rcsb pdb:1WQV|rcsb pdb:1WSS|rcsb pdb:1WTG|rcsb pdb:1WUN|rcsb pdb:1WV7|rcsb pdb:1Z6J|rcsb pdb:2A2Q|rcsb pdb:2AEI|rcsb pdb:2AER|rcsb pdb:2B7D|rcsb pdb:2B8O|rcsb pdb:2C4F|rcsb pdb:2CEF|rcsb pdb:2CEH|rcsb pdb:2CEZ|rcsb pdb:2CFJ|rcsb pdb:2EC9|rcsb pdb:2F9B|rcsb pdb:2FIR|rcsb pdb:2FLB|rcsb pdb:2FLR|rcsb pdb:2HFT|rcsb pdb:2PUQ|rcsb pdb:2ZP0|rcsb pdb:2ZWL|rcsb pdb:2ZZU|rcsb pdb:3ELA|rcsb pdb:3TH2|rcsb pdb:3TH3|rcsb pdb:3TH4|rcsb pdb:4IBL|rcsb pdb:4M7L|rcsb pdb:4YLQ|rcsb pdb:4Z6A|rcsb pdb:4ZMA|rcsb pdb:5W06|rcsb pdb:6R2W|reactome:R-HSA-140834|reactome:R-HSA-9031628|rcsb pdb:1TFH|dip:DIP-6136N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:rh0B38TSfTX+lvU5OyBwEbVndFA9606	rogid:/9cwpvhO2XibmA8HkQaSLRfA6689606	rigid:/PtECSbrVbOdXhULa7GC8Kj3Fbk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)