#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9NBK5-2 uniprotkb:Q8T0S6 intact:EBI-15596484|ensemblmetazoa:FBpp0074691 intact:EBI-101858|uniprotkb:Q9V8W4|ensemblmetazoa:FBpp0085688|ensemblmetazoa:FBpp0304253 psi-mi:q9nbk5-2(display_long)|uniprotkb:trc(gene name)|psi-mi:trc(display_short)|uniprotkb:NDR protein kinase(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 38-like(gene name synonym)|uniprotkb:CG8637(orf name)|uniprotkb:Serine/threonine-protein kinase tricorner(gene name synonym) psi-mi:hippo_drome(display_long)|uniprotkb:hpo(gene name)|psi-mi:hpo(display_short)|uniprotkb:dMST(gene name synonym)|uniprotkb:Drosophila homolog of MST1 and MST2(gene name synonym)|uniprotkb:STE20-like kinase MST(gene name synonym)|uniprotkb:CG11228(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Emoto et al. (2006) pubmed:16906135|doi:10.1038/nature05090|imex:IM-21449 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15596493|imex:IM-21449-1|dip:DIP-191608E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-184895(isoform-parent)|ensemblmetazoa:FBgn0003744(gene)|ensemblmetazoa:FBtr0074922(transcript) interpro:IPR036674|mint:Q8T0S6|rcsb pdb:6BN1|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150|reactome:R-DME-451806|interpro:IPR024205|refseq:NP_611427.1|flybase:FBgn0261456|ensemblmetazoa:FBgn0261456(gene)|ensemblmetazoa:FBtr0086500(transcript)|ensemblmetazoa:FBtr0331920(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035265"(organ growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0042127"(regulation of cell population proliferation)|refseq:NP_001261092.1|dip:DIP-17921N psi-mi:"MI:0465"(dip) isoform-comment:No experimental confirmation available. - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:WO3wnmDWApaXPN5qGRPygaO3NXY7227 rogid:KpEHzTCz7M84Nh6cjyyS55/p+XE7227 rigid:8wMXd3Gm5aT0gftiAmePlwGcBF8 false flag tag:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9VA38 uniprotkb:Q8T0S6 intact:EBI-82717|ensemblmetazoa:FBpp0085082 intact:EBI-101858|uniprotkb:Q9V8W4|ensemblmetazoa:FBpp0085688|ensemblmetazoa:FBpp0304253 psi-mi:warts_drome(display_long)|uniprotkb:wts(gene name)|psi-mi:wts(display_short)|uniprotkb:CG12072(orf name) psi-mi:hippo_drome(display_long)|uniprotkb:hpo(gene name)|psi-mi:hpo(display_short)|uniprotkb:dMST(gene name synonym)|uniprotkb:Drosophila homolog of MST1 and MST2(gene name synonym)|uniprotkb:STE20-like kinase MST(gene name synonym)|uniprotkb:CG11228(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Emoto et al. (2006) pubmed:16906135|doi:10.1038/nature05090|imex:IM-21449 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15596514|imex:IM-21449-2|dip:DIP-191609E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0011739(gene)|ensemblmetazoa:FBtr0085720(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001708"(cell fate specification)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120080"(obsolete negative regulation of microfilament motor activity)|go:"GO:1904504"(positive regulation of lipophagy)|interpro:IPR000719(Protein kinase, core)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028742|reactome:R-DME-2028269|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045571"(negative regulation of imaginal disc growth)|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150|reactome:R-DME-390178|reactome:R-DME-451806|refseq:NP_733403.1|flybase:FBgn0011739|dip:DIP-20374N interpro:IPR036674|mint:Q8T0S6|rcsb pdb:6BN1|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150|reactome:R-DME-451806|interpro:IPR024205|refseq:NP_611427.1|flybase:FBgn0261456|ensemblmetazoa:FBgn0261456(gene)|ensemblmetazoa:FBtr0086500(transcript)|ensemblmetazoa:FBtr0331920(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035265"(organ growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0042127"(regulation of cell population proliferation)|refseq:NP_001261092.1|dip:DIP-17921N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:yBO+BhKuFTQXEj2ywUMv0/brvMw7227 rogid:KpEHzTCz7M84Nh6cjyyS55/p+XE7227 rigid:C2J1FPcw969CQEbQahH6GsahyfE false myc tag:c-c - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NBK5-2 uniprotkb:Q8T0S6 intact:EBI-15596484|ensemblmetazoa:FBpp0074691 intact:EBI-101858|uniprotkb:Q9V8W4|ensemblmetazoa:FBpp0085688|ensemblmetazoa:FBpp0304253 psi-mi:q9nbk5-2(display_long)|uniprotkb:trc(gene name)|psi-mi:trc(display_short)|uniprotkb:NDR protein kinase(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 38-like(gene name synonym)|uniprotkb:CG8637(orf name)|uniprotkb:Serine/threonine-protein kinase tricorner(gene name synonym) psi-mi:hippo_drome(display_long)|uniprotkb:hpo(gene name)|psi-mi:hpo(display_short)|uniprotkb:dMST(gene name synonym)|uniprotkb:Drosophila homolog of MST1 and MST2(gene name synonym)|uniprotkb:STE20-like kinase MST(gene name synonym)|uniprotkb:CG11228(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Emoto et al. (2006) pubmed:16906135|doi:10.1038/nature05090|imex:IM-21449 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15596533|imex:IM-21449-3|dip:DIP-191608E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-184895(isoform-parent)|ensemblmetazoa:FBgn0003744(gene)|ensemblmetazoa:FBtr0074922(transcript) interpro:IPR036674|mint:Q8T0S6|rcsb pdb:6BN1|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150|reactome:R-DME-451806|interpro:IPR024205|refseq:NP_611427.1|flybase:FBgn0261456|ensemblmetazoa:FBgn0261456(gene)|ensemblmetazoa:FBtr0086500(transcript)|ensemblmetazoa:FBtr0331920(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035265"(organ growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0042127"(regulation of cell population proliferation)|refseq:NP_001261092.1|dip:DIP-17921N psi-mi:"MI:0465"(dip) isoform-comment:No experimental confirmation available. - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:WO3wnmDWApaXPN5qGRPygaO3NXY7227 rogid:KpEHzTCz7M84Nh6cjyyS55/p+XE7227 rigid:8wMXd3Gm5aT0gftiAmePlwGcBF8 false ha tag:?-? flag tag:c-c|sufficient binding region:343-669 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)