#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P70290	uniprotkb:Q80VW5	intact:EBI-8315951|ensembl:ENSMUSP00000033775|intact:MINT-4094335	intact:EBI-7417603|ensembl:ENSMUSP00000081557|uniprotkb:A2AGD2|uniprotkb:Q80TC2|intact:MINT-1895268|uniprotkb:Q5MLF5|uniprotkb:Q5MLF8|uniprotkb:Q5MLF2|uniprotkb:Q3TZC8|uniprotkb:I6MML6|uniprotkb:Q5MLF1|uniprotkb:Q5MLF3|uniprotkb:Q80VW4|uniprotkb:Q5MLF6|uniprotkb:Q5MLF9|uniprotkb:Q5MLF7|uniprotkb:I6MML7|uniprotkb:Q5MLF4	psi-mi:em55_mouse(display_long)|uniprotkb:Mpp1(gene name)|psi-mi:Mpp1(display_short)|uniprotkb:Membrane protein, palmitoylated 1(gene name synonym)	psi-mi:whrn_mouse(display_long)|uniprotkb:Whrn(gene name)|psi-mi:Whrn(display_short)|uniprotkb:Dfnb31(gene name synonym)|uniprotkb:Kiaa1526(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Mburu et al. (2006)	pubmed:16829577|doi:10.1073/pnas.0600923103|imex:IM-23759	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15590478|imex:IM-23759-1|dip:DIP-197827E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000031402(gene)|ensembl:ENSMUST00000033775(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032420"(stereocilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035475|interpro:IPR036028|interpro:IPR036034|mint:P70290|refseq:NP_032647.1|dip:DIP-61219N	refseq:XP_017175899.1|ensembl:ENSMUSG00000039137(gene)|ensembl:ENSMUST00000084510(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002141"(stereocilia ankle link)|go:"GO:0002142"(stereocilia ankle link complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021694"(cerebellar Purkinje cell layer formation)|go:"GO:0030426"(growth cone)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032426"(stereocilium tip)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044303"(axon collateral)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0097440"(apical dendrite)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:1990227"(paranodal junction maintenance)|go:"GO:1990696"(USH2 complex)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR033028|interpro:IPR036034|mint:Q80VW5|rcsb pdb:6FDD|rcsb pdb:6FDE|rcsb pdb:6Y38|rcsb pdb:6Y9N|rcsb pdb:6Y9O|rcsb pdb:6Y9P|rcsb pdb:6Y9Q|refseq:NP_082916.1|refseq:NP_001008792.1|refseq:NP_001263300.1|refseq:NP_001008791.1|refseq:NP_001008793.1|dip:DIP-42047N	psi-mi:"MI:0465"(dip)	comment:mint	function:Necessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear|comment:mint|function:"Defects in Whrn are the cause of the phenotype whirler (wi). Mutants are characterized by deafness due to malformation of the cochlear inner and outer hair cells and by circling behavior. Stereocilia are shorter and wider than in wild-type animals and there is a decrease in the number of actin filaments in inner and outer hair cells. The number of outer hair cell stereocilia is reduced with increased spacing between them"	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:pIVFjZcKNpYbv/lWGedmeKsG/WU10090	rogid:6N5se4ijefLU6c1zlQobN/Hi8N810090	rigid:jxXKuMBM5GtSJCGArSO3kkMxKMQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P70290	uniprotkb:Q80VW5	intact:EBI-8315951|ensembl:ENSMUSP00000033775|intact:MINT-4094335	intact:EBI-7417603|ensembl:ENSMUSP00000081557|uniprotkb:A2AGD2|uniprotkb:Q80TC2|intact:MINT-1895268|uniprotkb:Q5MLF5|uniprotkb:Q5MLF8|uniprotkb:Q5MLF2|uniprotkb:Q3TZC8|uniprotkb:I6MML6|uniprotkb:Q5MLF1|uniprotkb:Q5MLF3|uniprotkb:Q80VW4|uniprotkb:Q5MLF6|uniprotkb:Q5MLF9|uniprotkb:Q5MLF7|uniprotkb:I6MML7|uniprotkb:Q5MLF4	psi-mi:em55_mouse(display_long)|uniprotkb:Mpp1(gene name)|psi-mi:Mpp1(display_short)|uniprotkb:Membrane protein, palmitoylated 1(gene name synonym)	psi-mi:whrn_mouse(display_long)|uniprotkb:Whrn(gene name)|psi-mi:Whrn(display_short)|uniprotkb:Dfnb31(gene name synonym)|uniprotkb:Kiaa1526(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mburu et al. (2006)	pubmed:16829577|doi:10.1073/pnas.0600923103|imex:IM-23759	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15590516|imex:IM-23759-3|dip:DIP-197827E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000031402(gene)|ensembl:ENSMUST00000033775(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032420"(stereocilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035475|interpro:IPR036028|interpro:IPR036034|mint:P70290|refseq:NP_032647.1|dip:DIP-61219N	refseq:XP_017175899.1|ensembl:ENSMUSG00000039137(gene)|ensembl:ENSMUST00000084510(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002141"(stereocilia ankle link)|go:"GO:0002142"(stereocilia ankle link complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021694"(cerebellar Purkinje cell layer formation)|go:"GO:0030426"(growth cone)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032426"(stereocilium tip)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044303"(axon collateral)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0097440"(apical dendrite)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:1990227"(paranodal junction maintenance)|go:"GO:1990696"(USH2 complex)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR033028|interpro:IPR036034|mint:Q80VW5|rcsb pdb:6FDD|rcsb pdb:6FDE|rcsb pdb:6Y38|rcsb pdb:6Y9N|rcsb pdb:6Y9O|rcsb pdb:6Y9P|rcsb pdb:6Y9Q|refseq:NP_082916.1|refseq:NP_001008792.1|refseq:NP_001263300.1|refseq:NP_001008791.1|refseq:NP_001008793.1|dip:DIP-42047N	psi-mi:"MI:0465"(dip)	comment:mint	function:Necessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear|comment:mint|function:"Defects in Whrn are the cause of the phenotype whirler (wi). Mutants are characterized by deafness due to malformation of the cochlear inner and outer hair cells and by circling behavior. Stereocilia are shorter and wider than in wild-type animals and there is a decrease in the number of actin filaments in inner and outer hair cells. The number of outer hair cell stereocilia is reduced with increased spacing between them"	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/05	2017/08/10	rogid:pIVFjZcKNpYbv/lWGedmeKsG/WU10090	rogid:6N5se4ijefLU6c1zlQobN/Hi8N810090	rigid:jxXKuMBM5GtSJCGArSO3kkMxKMQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P70290	uniprotkb:Q80VW5	intact:EBI-8315951|ensembl:ENSMUSP00000033775|intact:MINT-4094335	intact:EBI-7417603|ensembl:ENSMUSP00000081557|uniprotkb:A2AGD2|uniprotkb:Q80TC2|intact:MINT-1895268|uniprotkb:Q5MLF5|uniprotkb:Q5MLF8|uniprotkb:Q5MLF2|uniprotkb:Q3TZC8|uniprotkb:I6MML6|uniprotkb:Q5MLF1|uniprotkb:Q5MLF3|uniprotkb:Q80VW4|uniprotkb:Q5MLF6|uniprotkb:Q5MLF9|uniprotkb:Q5MLF7|uniprotkb:I6MML7|uniprotkb:Q5MLF4	psi-mi:em55_mouse(display_long)|uniprotkb:Mpp1(gene name)|psi-mi:Mpp1(display_short)|uniprotkb:Membrane protein, palmitoylated 1(gene name synonym)	psi-mi:whrn_mouse(display_long)|uniprotkb:Whrn(gene name)|psi-mi:Whrn(display_short)|uniprotkb:Dfnb31(gene name synonym)|uniprotkb:Kiaa1526(gene name synonym)	psi-mi:"MI:0096"(pull down)	Mburu et al. (2006)	pubmed:16829577|doi:10.1073/pnas.0600923103|imex:IM-23759	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15590495|imex:IM-23759-2|dip:DIP-197827E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000031402(gene)|ensembl:ENSMUST00000033775(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032420"(stereocilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035475|interpro:IPR036028|interpro:IPR036034|mint:P70290|refseq:NP_032647.1|dip:DIP-61219N	refseq:XP_017175899.1|ensembl:ENSMUSG00000039137(gene)|ensembl:ENSMUST00000084510(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002141"(stereocilia ankle link)|go:"GO:0002142"(stereocilia ankle link complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021694"(cerebellar Purkinje cell layer formation)|go:"GO:0030426"(growth cone)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032426"(stereocilium tip)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044303"(axon collateral)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0097440"(apical dendrite)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:1990227"(paranodal junction maintenance)|go:"GO:1990696"(USH2 complex)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR033028|interpro:IPR036034|mint:Q80VW5|rcsb pdb:6FDD|rcsb pdb:6FDE|rcsb pdb:6Y38|rcsb pdb:6Y9N|rcsb pdb:6Y9O|rcsb pdb:6Y9P|rcsb pdb:6Y9Q|refseq:NP_082916.1|refseq:NP_001008792.1|refseq:NP_001263300.1|refseq:NP_001008791.1|refseq:NP_001008793.1|dip:DIP-42047N	psi-mi:"MI:0465"(dip)	comment:mint	function:Necessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear|comment:mint|function:"Defects in Whrn are the cause of the phenotype whirler (wi). Mutants are characterized by deafness due to malformation of the cochlear inner and outer hair cells and by circling behavior. Stereocilia are shorter and wider than in wild-type animals and there is a decrease in the number of actin filaments in inner and outer hair cells. The number of outer hair cell stereocilia is reduced with increased spacing between them"	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:pIVFjZcKNpYbv/lWGedmeKsG/WU10090	rogid:6N5se4ijefLU6c1zlQobN/Hi8N810090	rigid:jxXKuMBM5GtSJCGArSO3kkMxKMQ	false	35s radiolabel:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P70290	uniprotkb:Q80VW5	intact:EBI-8315951|ensembl:ENSMUSP00000033775|intact:MINT-4094335	intact:EBI-7417603|ensembl:ENSMUSP00000081557|uniprotkb:A2AGD2|uniprotkb:Q80TC2|intact:MINT-1895268|uniprotkb:Q5MLF5|uniprotkb:Q5MLF8|uniprotkb:Q5MLF2|uniprotkb:Q3TZC8|uniprotkb:I6MML6|uniprotkb:Q5MLF1|uniprotkb:Q5MLF3|uniprotkb:Q80VW4|uniprotkb:Q5MLF6|uniprotkb:Q5MLF9|uniprotkb:Q5MLF7|uniprotkb:I6MML7|uniprotkb:Q5MLF4	psi-mi:em55_mouse(display_long)|uniprotkb:Mpp1(gene name)|psi-mi:Mpp1(display_short)|uniprotkb:Membrane protein, palmitoylated 1(gene name synonym)	psi-mi:whrn_mouse(display_long)|uniprotkb:Whrn(gene name)|psi-mi:Whrn(display_short)|uniprotkb:Dfnb31(gene name synonym)|uniprotkb:Kiaa1526(gene name synonym)	psi-mi:"MI:0096"(pull down)	Mburu et al. (2006)	pubmed:16829577|doi:10.1073/pnas.0600923103|imex:IM-23759	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15590533|imex:IM-23759-4|dip:DIP-197827E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000031402(gene)|ensembl:ENSMUST00000033775(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032420"(stereocilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035475|interpro:IPR036028|interpro:IPR036034|mint:P70290|refseq:NP_032647.1|dip:DIP-61219N	refseq:XP_017175899.1|ensembl:ENSMUSG00000039137(gene)|ensembl:ENSMUST00000084510(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002141"(stereocilia ankle link)|go:"GO:0002142"(stereocilia ankle link complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021694"(cerebellar Purkinje cell layer formation)|go:"GO:0030426"(growth cone)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032426"(stereocilium tip)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044303"(axon collateral)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0097440"(apical dendrite)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:1990227"(paranodal junction maintenance)|go:"GO:1990696"(USH2 complex)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR033028|interpro:IPR036034|mint:Q80VW5|rcsb pdb:6FDD|rcsb pdb:6FDE|rcsb pdb:6Y38|rcsb pdb:6Y9N|rcsb pdb:6Y9O|rcsb pdb:6Y9P|rcsb pdb:6Y9Q|refseq:NP_082916.1|refseq:NP_001008792.1|refseq:NP_001263300.1|refseq:NP_001008791.1|refseq:NP_001008793.1|dip:DIP-42047N	psi-mi:"MI:0465"(dip)	comment:mint	function:Necessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear|comment:mint|function:"Defects in Whrn are the cause of the phenotype whirler (wi). Mutants are characterized by deafness due to malformation of the cochlear inner and outer hair cells and by circling behavior. Stereocilia are shorter and wider than in wild-type animals and there is a decrease in the number of actin filaments in inner and outer hair cells. The number of outer hair cell stereocilia is reduced with increased spacing between them"	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:pIVFjZcKNpYbv/lWGedmeKsG/WU10090	rogid:6N5se4ijefLU6c1zlQobN/Hi8N810090	rigid:jxXKuMBM5GtSJCGArSO3kkMxKMQ	false	sufficient binding region:323-466|glutathione s tranferase tag:n-n	35s radiolabel:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)