#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8WXF7	uniprotkb:Q9UBP0	intact:EBI-2410266|uniprotkb:A6NND5|uniprotkb:O95890|uniprotkb:Q96FK0|uniprotkb:A8K2C0|uniprotkb:G5E9T1|uniprotkb:Q69YH7|ensembl:ENSP00000351155	intact:EBI-1222832|uniprotkb:Q9UPR9|uniprotkb:A7E2A7|ensembl:ENSP00000320885	psi-mi:atla1_human(display_long)|uniprotkb:ATL1(gene name)|psi-mi:ATL1(display_short)|uniprotkb:GBP3(gene name synonym)|uniprotkb:SPG3A(gene name synonym)|uniprotkb:Spastic paraplegia 3 protein A(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 3(gene name synonym)|uniprotkb:GTP-binding protein 3(gene name synonym)|uniprotkb:Brain-specific GTP-binding protein(gene name synonym)	psi-mi:spast_human(display_long)|uniprotkb:SPAST(gene name)|psi-mi:SPAST(display_short)|uniprotkb:KIAA1083(gene name synonym)|uniprotkb:SPG4(gene name synonym)|uniprotkb:ADPSP(gene name synonym)|uniprotkb:FSP2(gene name synonym)|uniprotkb:Spastic paraplegia 4 protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Evans et al. (2006)	pubmed:16815977|doi:10.1073/pnas.0510863103|imex:IM-23755	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15590210|imex:IM-23755-1|dip:DIP-197823E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001121185.1|refseq:NP_056999.2|refseq:NP_853629.2|dip:DIP-53502N|ensembl:ENSG00000198513(gene)|ensembl:ENST00000358385(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q8WXF7|rcsb pdb:3Q5D|rcsb pdb:3Q5E|rcsb pdb:3QNU|rcsb pdb:3QOF|rcsb pdb:4IDN|rcsb pdb:4IDO|rcsb pdb:4IDP|rcsb pdb:4IDQ|rcsb pdb:6B9D|rcsb pdb:6B9E|rcsb pdb:6B9F|rcsb pdb:6B9G|rcsb pdb:6XJN	refseq:NP_055761.2|refseq:NP_955468.1|dip:DIP-38418N|ensembl:ENSG00000021574(gene)|ensembl:ENST00000315285(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008152"(metabolic process)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030496"(midbody)|go:"GO:0031117"(positive regulation of microtubule depolymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032506"(cytokinetic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051013"(microtubule severing)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|rcsb pdb:6PEN|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-9668328|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090148"(membrane fission)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR017179(Spastin)|interpro:IPR027417|interpro:IPR035106|interpro:IPR041569|rcsb pdb:3EAB|rcsb pdb:3VFD|rcsb pdb:5Z6Q|rcsb pdb:5Z6R|rcsb pdb:6PEK	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:xHgqrEBVA57vg40bCwdpIrhaWIw9606	rogid:E8b4FF6pWwyVd9teIInSCY4RzQE9606	rigid:/zl1N4VY+lk7fVZabOOEAzXjELM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WXF7-1	uniprotkb:Q9UBP0	intact:EBI-15590227|ensembl:ENSP00000351155	intact:EBI-1222832|uniprotkb:Q9UPR9|uniprotkb:A7E2A7|ensembl:ENSP00000320885	psi-mi:q8wxf7-1(display_long)|uniprotkb:ATL1(gene name)|psi-mi:ATL1(display_short)|uniprotkb:GBP3(gene name synonym)|uniprotkb:SPG3A(gene name synonym)|uniprotkb:Brain-specific GTP-binding protein(gene name synonym)|uniprotkb:GTP-binding protein 3(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 3(gene name synonym)|uniprotkb:Spastic paraplegia 3 protein A(gene name synonym)	psi-mi:spast_human(display_long)|uniprotkb:SPAST(gene name)|psi-mi:SPAST(display_short)|uniprotkb:KIAA1083(gene name synonym)|uniprotkb:SPG4(gene name synonym)|uniprotkb:ADPSP(gene name synonym)|uniprotkb:FSP2(gene name synonym)|uniprotkb:Spastic paraplegia 4 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Evans et al. (2006)	pubmed:16815977|doi:10.1073/pnas.0510863103|imex:IM-23755	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15590258|imex:IM-23755-3|dip:DIP-197823E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2410266(isoform-parent)|ensembl:ENST00000358385(transcript)|ensembl:ENSG00000198513(gene)	refseq:NP_055761.2|refseq:NP_955468.1|dip:DIP-38418N|ensembl:ENSG00000021574(gene)|ensembl:ENST00000315285(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008152"(metabolic process)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030496"(midbody)|go:"GO:0031117"(positive regulation of microtubule depolymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032506"(cytokinetic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051013"(microtubule severing)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|rcsb pdb:6PEN|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-9668328|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090148"(membrane fission)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR017179(Spastin)|interpro:IPR027417|interpro:IPR035106|interpro:IPR041569|rcsb pdb:3EAB|rcsb pdb:3VFD|rcsb pdb:5Z6Q|rcsb pdb:5Z6R|rcsb pdb:6PEK	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:xHgqrEBVA57vg40bCwdpIrhaWIw9606	rogid:E8b4FF6pWwyVd9teIInSCY4RzQE9606	rigid:/zl1N4VY+lk7fVZabOOEAzXjELM	false	glutathione s tranferase tag:?-?|sufficient binding region:408-558	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q8WXF7-1	uniprotkb:Q9UBP0	intact:EBI-15590227|ensembl:ENSP00000351155	intact:EBI-1222832|uniprotkb:Q9UPR9|uniprotkb:A7E2A7|ensembl:ENSP00000320885	psi-mi:q8wxf7-1(display_long)|uniprotkb:ATL1(gene name)|psi-mi:ATL1(display_short)|uniprotkb:GBP3(gene name synonym)|uniprotkb:SPG3A(gene name synonym)|uniprotkb:Brain-specific GTP-binding protein(gene name synonym)|uniprotkb:GTP-binding protein 3(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 3(gene name synonym)|uniprotkb:Spastic paraplegia 3 protein A(gene name synonym)	psi-mi:spast_human(display_long)|uniprotkb:SPAST(gene name)|psi-mi:SPAST(display_short)|uniprotkb:KIAA1083(gene name synonym)|uniprotkb:SPG4(gene name synonym)|uniprotkb:ADPSP(gene name synonym)|uniprotkb:FSP2(gene name synonym)|uniprotkb:Spastic paraplegia 4 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Evans et al. (2006)	pubmed:16815977|doi:10.1073/pnas.0510863103|imex:IM-23755	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15590281|imex:IM-23755-4|dip:DIP-197823E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2410266(isoform-parent)|ensembl:ENST00000358385(transcript)|ensembl:ENSG00000198513(gene)	refseq:NP_055761.2|refseq:NP_955468.1|dip:DIP-38418N|ensembl:ENSG00000021574(gene)|ensembl:ENST00000315285(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008152"(metabolic process)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030496"(midbody)|go:"GO:0031117"(positive regulation of microtubule depolymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032506"(cytokinetic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051013"(microtubule severing)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|rcsb pdb:6PEN|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-9668328|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090148"(membrane fission)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR017179(Spastin)|interpro:IPR027417|interpro:IPR035106|interpro:IPR041569|rcsb pdb:3EAB|rcsb pdb:3VFD|rcsb pdb:5Z6Q|rcsb pdb:5Z6R|rcsb pdb:6PEK	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:xHgqrEBVA57vg40bCwdpIrhaWIw9606	rogid:E8b4FF6pWwyVd9teIInSCY4RzQE9606	rigid:/zl1N4VY+lk7fVZabOOEAzXjELM	false	his tag:?-?	ha tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8WXF7-1	uniprotkb:Q9UBP0	intact:EBI-15590227|ensembl:ENSP00000351155	intact:EBI-1222832|uniprotkb:Q9UPR9|uniprotkb:A7E2A7|ensembl:ENSP00000320885	psi-mi:q8wxf7-1(display_long)|uniprotkb:ATL1(gene name)|psi-mi:ATL1(display_short)|uniprotkb:GBP3(gene name synonym)|uniprotkb:SPG3A(gene name synonym)|uniprotkb:Brain-specific GTP-binding protein(gene name synonym)|uniprotkb:GTP-binding protein 3(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 3(gene name synonym)|uniprotkb:Spastic paraplegia 3 protein A(gene name synonym)	psi-mi:spast_human(display_long)|uniprotkb:SPAST(gene name)|psi-mi:SPAST(display_short)|uniprotkb:KIAA1083(gene name synonym)|uniprotkb:SPG4(gene name synonym)|uniprotkb:ADPSP(gene name synonym)|uniprotkb:FSP2(gene name synonym)|uniprotkb:Spastic paraplegia 4 protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Evans et al. (2006)	pubmed:16815977|doi:10.1073/pnas.0510863103|imex:IM-23755	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15590239|imex:IM-23755-2|dip:DIP-197823E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2410266(isoform-parent)|ensembl:ENST00000358385(transcript)|ensembl:ENSG00000198513(gene)	refseq:NP_055761.2|refseq:NP_955468.1|dip:DIP-38418N|ensembl:ENSG00000021574(gene)|ensembl:ENST00000315285(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008152"(metabolic process)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030496"(midbody)|go:"GO:0031117"(positive regulation of microtubule depolymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032506"(cytokinetic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051013"(microtubule severing)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|rcsb pdb:6PEN|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-9668328|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090148"(membrane fission)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR017179(Spastin)|interpro:IPR027417|interpro:IPR035106|interpro:IPR041569|rcsb pdb:3EAB|rcsb pdb:3VFD|rcsb pdb:5Z6Q|rcsb pdb:5Z6R|rcsb pdb:6PEK	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:xHgqrEBVA57vg40bCwdpIrhaWIw9606	rogid:E8b4FF6pWwyVd9teIInSCY4RzQE9606	rigid:/zl1N4VY+lk7fVZabOOEAzXjELM	false	sufficient binding region:408-558	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8WXF7-1	uniprotkb:Q9UBP0	intact:EBI-15590227|ensembl:ENSP00000351155	intact:EBI-1222832|uniprotkb:Q9UPR9|uniprotkb:A7E2A7|ensembl:ENSP00000320885	psi-mi:q8wxf7-1(display_long)|uniprotkb:ATL1(gene name)|psi-mi:ATL1(display_short)|uniprotkb:GBP3(gene name synonym)|uniprotkb:SPG3A(gene name synonym)|uniprotkb:Brain-specific GTP-binding protein(gene name synonym)|uniprotkb:GTP-binding protein 3(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 3(gene name synonym)|uniprotkb:Spastic paraplegia 3 protein A(gene name synonym)	psi-mi:spast_human(display_long)|uniprotkb:SPAST(gene name)|psi-mi:SPAST(display_short)|uniprotkb:KIAA1083(gene name synonym)|uniprotkb:SPG4(gene name synonym)|uniprotkb:ADPSP(gene name synonym)|uniprotkb:FSP2(gene name synonym)|uniprotkb:Spastic paraplegia 4 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Evans et al. (2006)	pubmed:16815977|doi:10.1073/pnas.0510863103|imex:IM-23755	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15590304|imex:IM-23755-5|dip:DIP-197823E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2410266(isoform-parent)|ensembl:ENST00000358385(transcript)|ensembl:ENSG00000198513(gene)	refseq:NP_055761.2|refseq:NP_955468.1|dip:DIP-38418N|ensembl:ENSG00000021574(gene)|ensembl:ENST00000315285(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008152"(metabolic process)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030496"(midbody)|go:"GO:0031117"(positive regulation of microtubule depolymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032506"(cytokinetic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051013"(microtubule severing)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|rcsb pdb:6PEN|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-9668328|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090148"(membrane fission)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR017179(Spastin)|interpro:IPR027417|interpro:IPR035106|interpro:IPR041569|rcsb pdb:3EAB|rcsb pdb:3VFD|rcsb pdb:5Z6Q|rcsb pdb:5Z6R|rcsb pdb:6PEK	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:xHgqrEBVA57vg40bCwdpIrhaWIw9606	rogid:E8b4FF6pWwyVd9teIInSCY4RzQE9606	rigid:/zl1N4VY+lk7fVZabOOEAzXjELM	false	maltose binding protein tag:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)