#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P31384 uniprotkb:P39016 intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C intact:EBI-2052996|uniprotkb:D6VTX5|ensemblfungi:YGL178W psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:mpt5_yeast(display_long)|uniprotkb:HTR1(gene name synonym)|uniprotkb:PUF5(gene name synonym)|uniprotkb:Protein HTR1(gene name synonym)|uniprotkb:BIC834(orf name)|uniprotkb:YGL178W(locus name)|uniprotkb:MPT5(gene name)|psi-mi:MPT5(display_short)|uniprotkb:Pumilio homology domain family member 5(gene name synonym) psi-mi:"MI:0096"(pull down) Goldstrohm et al. (2006) pubmed:16715093|doi:10.1038/nsmb1100|imex:IM-8387 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16226402|imex:IM-8387-11|dip:DIP-57084E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C refseq:NP_011337.1|sgd:S000003146|dip:DIP-2271N|mint:P39016|ensemblfungi:YGL178W(gene)|ensemblfungi:YGL178W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:5BYM|rcsb pdb:5BZ1|rcsb pdb:5BZ5|rcsb pdb:5BZU|rcsb pdb:5BZV psi-mi:"MI:0465"(dip) crc64:5CDB2E8FEDDBEF6F crc64:6B289BAF3CEA2200 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/10 2017/08/10 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 rogid:tWA8mxLeerefKvNZOERVljO8uHQ559292 rigid:kiASa6RpqvM5QFvsQwUW90l1Cvs false t7 tag:?-? calmodulin binding peptide plus protein a tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P31384 uniprotkb:P39008 intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Goldstrohm et al. (2006) pubmed:16715093|doi:10.1038/nsmb1100|imex:IM-8387 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16226383|imex:IM-8387-10|dip:DIP-3221E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N psi-mi:"MI:0465"(dip) crc64:5CDB2E8FEDDBEF6F crc64:F3CAF97106A65933 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/10 2017/08/10 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 rigid:6uSwKxy42yYSveJ5MPf89QOOw4s false - calmodulin binding peptide plus protein a tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P39008 uniprotkb:P39016 intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C intact:EBI-2052996|uniprotkb:D6VTX5|ensemblfungi:YGL178W psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:mpt5_yeast(display_long)|uniprotkb:HTR1(gene name synonym)|uniprotkb:PUF5(gene name synonym)|uniprotkb:Protein HTR1(gene name synonym)|uniprotkb:BIC834(orf name)|uniprotkb:YGL178W(locus name)|uniprotkb:MPT5(gene name)|psi-mi:MPT5(display_short)|uniprotkb:Pumilio homology domain family member 5(gene name synonym) psi-mi:"MI:0096"(pull down) Goldstrohm et al. (2006) pubmed:16715093|doi:10.1038/nsmb1100|imex:IM-8387 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16226362|imex:IM-8387-12|dip:DIP-57083E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N refseq:NP_011337.1|sgd:S000003146|dip:DIP-2271N|mint:P39016|ensemblfungi:YGL178W(gene)|ensemblfungi:YGL178W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:5BYM|rcsb pdb:5BZ1|rcsb pdb:5BZ5|rcsb pdb:5BZU|rcsb pdb:5BZV psi-mi:"MI:0465"(dip) crc64:F3CAF97106A65933 crc64:6B289BAF3CEA2200 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/10 2017/08/10 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 rogid:tWA8mxLeerefKvNZOERVljO8uHQ559292 rigid:2fksR3lAc8Qy5ru10DkPE8Fo+/E false t7 tag:?-? calmodulin binding peptide plus protein a tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12517 uniprotkb:P39016 intact:EBI-38519|uniprotkb:D6W1S0|ensemblfungi:YOL149W intact:EBI-2052996|uniprotkb:D6VTX5|ensemblfungi:YGL178W psi-mi:dcp1_yeast(display_long)|uniprotkb:DCP1(gene name)|psi-mi:DCP1(display_short)|uniprotkb:YOL149W(locus name) psi-mi:mpt5_yeast(display_long)|uniprotkb:HTR1(gene name synonym)|uniprotkb:PUF5(gene name synonym)|uniprotkb:Protein HTR1(gene name synonym)|uniprotkb:BIC834(orf name)|uniprotkb:YGL178W(locus name)|uniprotkb:MPT5(gene name)|psi-mi:MPT5(display_short)|uniprotkb:Pumilio homology domain family member 5(gene name synonym) psi-mi:"MI:0096"(pull down) Goldstrohm et al. (2006) pubmed:16715093|doi:10.1038/nsmb1100|imex:IM-8387 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16226423|imex:IM-8387-13|dip:DIP-57086E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014492.1|sgd:S000005509|mint:Q12517|dip:DIP-1288N|ensemblfungi:YOL149W(gene)|ensemblfungi:YOL149W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0098745"(Dcp1-Dcp2 complex)|interpro:IPR010334(Dcp1-like decapping)|rcsb pdb:1Q67|rcsb pdb:6Y3Z|reactome:R-SCE-430039|reactome:R-SCE-450385|reactome:R-SCE-450513 refseq:NP_011337.1|sgd:S000003146|dip:DIP-2271N|mint:P39016|ensemblfungi:YGL178W(gene)|ensemblfungi:YGL178W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:5BYM|rcsb pdb:5BZ1|rcsb pdb:5BZ5|rcsb pdb:5BZU|rcsb pdb:5BZV psi-mi:"MI:0465"(dip) crc64:8456B1C96C121C4D crc64:6B289BAF3CEA2200 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/10 2017/08/10 rogid:CXLHokbNWY54t80lw79Or4Wmb1g559292 rogid:tWA8mxLeerefKvNZOERVljO8uHQ559292 rigid:CrBAO4V0z67WPkIj5icIsF6F5eY false t7 tag:?-? calmodulin binding peptide plus protein a tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P39517 uniprotkb:P39016 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C intact:EBI-2052996|uniprotkb:D6VTX5|ensemblfungi:YGL178W psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:mpt5_yeast(display_long)|uniprotkb:HTR1(gene name synonym)|uniprotkb:PUF5(gene name synonym)|uniprotkb:Protein HTR1(gene name synonym)|uniprotkb:BIC834(orf name)|uniprotkb:YGL178W(locus name)|uniprotkb:MPT5(gene name)|psi-mi:MPT5(display_short)|uniprotkb:Pumilio homology domain family member 5(gene name synonym) psi-mi:"MI:0096"(pull down) Goldstrohm et al. (2006) pubmed:16715093|doi:10.1038/nsmb1100|imex:IM-8387 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16226444|imex:IM-8387-14|dip:DIP-57087E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 refseq:NP_011337.1|sgd:S000003146|dip:DIP-2271N|mint:P39016|ensemblfungi:YGL178W(gene)|ensemblfungi:YGL178W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:5BYM|rcsb pdb:5BZ1|rcsb pdb:5BZ5|rcsb pdb:5BZU|rcsb pdb:5BZV psi-mi:"MI:0465"(dip) crc64:062CFA56DF6F2CEE crc64:6B289BAF3CEA2200 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/10 2017/08/10 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 rogid:tWA8mxLeerefKvNZOERVljO8uHQ559292 rigid:RShFm7bxaDsShmeEMQMYrB5SATw false t7 tag:?-? calmodulin binding peptide plus protein a tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q17345 uniprotkb:Q09487 intact:EBI-331358|ensemblmetazoa:Y56A3A.20.1 intact:EBI-322819|ensemblmetazoa:C30G12.7.1 psi-mi:cnot7_caeel(display_long)|uniprotkb:Y56A3A.20(orf name)|uniprotkb:ccf-1(gene name)|psi-mi:ccf-1(display_short)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:q09487_caeel(display_long)|uniprotkb:puf-8(gene name)|psi-mi:puf-8(display_short)|uniprotkb:CELE_C30G12.7(orf name)|uniprotkb:C30G12.7(orf name) psi-mi:"MI:0096"(pull down) Goldstrohm et al. (2006) pubmed:16715093|doi:10.1038/nsmb1100|imex:IM-8387 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16226465|imex:IM-8387-9|dip:DIP-57092E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499553.1|wormbase:Y56A3A.20|dip:DIP-29083N|ensemblmetazoa:WBGene00000369(gene)|ensemblmetazoa:Y56A3A.20.1(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0043186"(P granule)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|go:"GO:0030015"(CCR4-NOT core complex) refseq:NP_495523.3|wormbase:C30G12.7|ensemblmetazoa:C30G12.7.1(transcript)|ensemblmetazoa:WBGene00004244(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043186"(P granule)|go:"GO:0043409"(negative regulation of MAPK cascade)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:6NOD|interpro:IPR016024(Armadillo-type fold)|dip:DIP-27165N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/10 2017/08/10 rogid:sAQ34vRYj8W+D4ifvJAcA+rBwH46239 rogid:B2kn67Y4qE5ReRbB3b8r2sEzl1o6239 rigid:+ku9OmCe2oTbVO9PSzcuLLDUhe0 false t7 tag:?-? sufficient binding region:142-535|glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UFF9 uniprotkb:Q14671 intact:EBI-16226490 intact:EBI-948453|ensembl:ENSP00000257075|uniprotkb:Q5VXY7|uniprotkb:Q9HAN1|intact:EBI-2842591|uniprotkb:E9PCJ0|uniprotkb:Q53HH5|uniprotkb:B4DG92|uniprotkb:A8K6W4|uniprotkb:D3DPN3 psi-mi:cnot8(display_long) psi-mi:pum1_human(display_long)|uniprotkb:PUM1(gene name)|psi-mi:PUM1(display_short)|uniprotkb:KIAA0099(gene name synonym)|uniprotkb:PUMH1(gene name synonym) psi-mi:"MI:0096"(pull down) Goldstrohm et al. (2006) pubmed:16715093|doi:10.1038/nsmb1100|imex:IM-8387 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16226492|imex:IM-8387-1|dip:DIP-57094E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000134644(gene)|ensembl:ENST00000257075(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0048863"(stem cell differentiation)|interpro:IPR033712|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0061157"(mRNA destabilization)|mint:Q14671|rcsb pdb:1IB2|rcsb pdb:1M8W|rcsb pdb:1M8X|rcsb pdb:1M8Y|rcsb pdb:1M8Z|rcsb pdb:2YJY|rcsb pdb:3BSB|rcsb pdb:3BSX|rcsb pdb:3Q0L|rcsb pdb:3Q0M|rcsb pdb:3Q0N|rcsb pdb:3Q0O|rcsb pdb:3Q0P|rcsb pdb:5YKH|rcsb pdb:5YKI|reactome:R-HSA-432722|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|refseq:NP_001018494.1|refseq:NP_055491.1|dip:DIP-29082N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/10 2017/08/10 - rogid:tGsSgrvQ/Ehnm3UC5IO4CHhCrFs9606 - false t7 tag:?-? sufficient binding region:828-1176|glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39008 uniprotkb:P39016 intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C intact:EBI-2052996|uniprotkb:D6VTX5|ensemblfungi:YGL178W psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:mpt5_yeast(display_long)|uniprotkb:HTR1(gene name synonym)|uniprotkb:PUF5(gene name synonym)|uniprotkb:Protein HTR1(gene name synonym)|uniprotkb:BIC834(orf name)|uniprotkb:YGL178W(locus name)|uniprotkb:MPT5(gene name)|psi-mi:MPT5(display_short)|uniprotkb:Pumilio homology domain family member 5(gene name synonym) psi-mi:"MI:0096"(pull down) Goldstrohm et al. (2006) pubmed:16715093|doi:10.1038/nsmb1100|imex:IM-8387 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16226515|imex:IM-8387-6|dip:DIP-57083E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N refseq:NP_011337.1|sgd:S000003146|dip:DIP-2271N|mint:P39016|ensemblfungi:YGL178W(gene)|ensemblfungi:YGL178W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:5BYM|rcsb pdb:5BZ1|rcsb pdb:5BZ5|rcsb pdb:5BZU|rcsb pdb:5BZV psi-mi:"MI:0465"(dip) crc64:F3CAF97106A65933 crc64:6B289BAF3CEA2200 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/10 2017/08/10 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 rogid:tWA8mxLeerefKvNZOERVljO8uHQ559292 rigid:2fksR3lAc8Qy5ru10DkPE8Fo+/E false maltose binding protein tag:?-? glutathione s tranferase tag:n-n|sufficient binding region:126-626 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q09487 uniprotkb:P39008 intact:EBI-322819|ensemblmetazoa:C30G12.7.1 intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C psi-mi:q09487_caeel(display_long)|uniprotkb:puf-8(gene name)|psi-mi:puf-8(display_short)|uniprotkb:CELE_C30G12.7(orf name)|uniprotkb:C30G12.7(orf name) psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Goldstrohm et al. (2006) pubmed:16715093|doi:10.1038/nsmb1100|imex:IM-8387 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16226538|imex:IM-8387-2|dip:DIP-57091E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495523.3|wormbase:C30G12.7|ensemblmetazoa:C30G12.7.1(transcript)|ensemblmetazoa:WBGene00004244(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043186"(P granule)|go:"GO:0043409"(negative regulation of MAPK cascade)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:6NOD|interpro:IPR016024(Armadillo-type fold)|dip:DIP-27165N sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N psi-mi:"MI:0465"(dip) - crc64:F3CAF97106A65933 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/10 2017/08/10 rogid:B2kn67Y4qE5ReRbB3b8r2sEzl1o6239 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 rigid:WfiQ3CNZlrInqu5Njfd8CpIMlCs false sufficient binding region:142-535|glutathione s tranferase tag:n-n t7 tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14671 uniprotkb:P39008 intact:EBI-948453|ensembl:ENSP00000257075|uniprotkb:Q5VXY7|uniprotkb:Q9HAN1|intact:EBI-2842591|uniprotkb:E9PCJ0|uniprotkb:Q53HH5|uniprotkb:B4DG92|uniprotkb:A8K6W4|uniprotkb:D3DPN3 intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C psi-mi:pum1_human(display_long)|uniprotkb:PUM1(gene name)|psi-mi:PUM1(display_short)|uniprotkb:KIAA0099(gene name synonym)|uniprotkb:PUMH1(gene name synonym) psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Goldstrohm et al. (2006) pubmed:16715093|doi:10.1038/nsmb1100|imex:IM-8387 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16226561|imex:IM-8387-3|dip:DIP-57093E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134644(gene)|ensembl:ENST00000257075(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0048863"(stem cell differentiation)|interpro:IPR033712|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0061157"(mRNA destabilization)|mint:Q14671|rcsb pdb:1IB2|rcsb pdb:1M8W|rcsb pdb:1M8X|rcsb pdb:1M8Y|rcsb pdb:1M8Z|rcsb pdb:2YJY|rcsb pdb:3BSB|rcsb pdb:3BSX|rcsb pdb:3Q0L|rcsb pdb:3Q0M|rcsb pdb:3Q0N|rcsb pdb:3Q0O|rcsb pdb:3Q0P|rcsb pdb:5YKH|rcsb pdb:5YKI|reactome:R-HSA-432722|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|refseq:NP_001018494.1|refseq:NP_055491.1|dip:DIP-29082N sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N psi-mi:"MI:0465"(dip) - crc64:F3CAF97106A65933 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/10 2017/08/10 rogid:tGsSgrvQ/Ehnm3UC5IO4CHhCrFs9606 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 rigid:oB0rK5TIJduRe/eeaKI2Mc/OqCM false sufficient binding region:828-1176|glutathione s tranferase tag:n-n t7 tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UFF9 uniprotkb:P39016 intact:EBI-16226490 intact:EBI-2052996|uniprotkb:D6VTX5|ensemblfungi:YGL178W psi-mi:cnot8(display_long) psi-mi:mpt5_yeast(display_long)|uniprotkb:HTR1(gene name synonym)|uniprotkb:PUF5(gene name synonym)|uniprotkb:Protein HTR1(gene name synonym)|uniprotkb:BIC834(orf name)|uniprotkb:YGL178W(locus name)|uniprotkb:MPT5(gene name)|psi-mi:MPT5(display_short)|uniprotkb:Pumilio homology domain family member 5(gene name synonym) psi-mi:"MI:0096"(pull down) Goldstrohm et al. (2006) pubmed:16715093|doi:10.1038/nsmb1100|imex:IM-8387 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16226630|imex:IM-8387-7|dip:DIP-57090E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_011337.1|sgd:S000003146|dip:DIP-2271N|mint:P39016|ensemblfungi:YGL178W(gene)|ensemblfungi:YGL178W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:5BYM|rcsb pdb:5BZ1|rcsb pdb:5BZ5|rcsb pdb:5BZU|rcsb pdb:5BZV psi-mi:"MI:0465"(dip) - crc64:6B289BAF3CEA2200 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/10 2017/08/10 - rogid:tWA8mxLeerefKvNZOERVljO8uHQ559292 - false t7 tag:?-? sufficient binding region:?-?|glutathione s tranferase tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q17345 uniprotkb:P39016 intact:EBI-331358|ensemblmetazoa:Y56A3A.20.1 intact:EBI-2052996|uniprotkb:D6VTX5|ensemblfungi:YGL178W psi-mi:cnot7_caeel(display_long)|uniprotkb:Y56A3A.20(orf name)|uniprotkb:ccf-1(gene name)|psi-mi:ccf-1(display_short)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:mpt5_yeast(display_long)|uniprotkb:HTR1(gene name synonym)|uniprotkb:PUF5(gene name synonym)|uniprotkb:Protein HTR1(gene name synonym)|uniprotkb:BIC834(orf name)|uniprotkb:YGL178W(locus name)|uniprotkb:MPT5(gene name)|psi-mi:MPT5(display_short)|uniprotkb:Pumilio homology domain family member 5(gene name synonym) psi-mi:"MI:0096"(pull down) Goldstrohm et al. (2006) pubmed:16715093|doi:10.1038/nsmb1100|imex:IM-8387 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16226607|imex:IM-8387-15|dip:DIP-57089E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499553.1|wormbase:Y56A3A.20|dip:DIP-29083N|ensemblmetazoa:WBGene00000369(gene)|ensemblmetazoa:Y56A3A.20.1(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0043186"(P granule)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|go:"GO:0030015"(CCR4-NOT core complex) refseq:NP_011337.1|sgd:S000003146|dip:DIP-2271N|mint:P39016|ensemblfungi:YGL178W(gene)|ensemblfungi:YGL178W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:5BYM|rcsb pdb:5BZ1|rcsb pdb:5BZ5|rcsb pdb:5BZU|rcsb pdb:5BZV psi-mi:"MI:0465"(dip) - crc64:6B289BAF3CEA2200 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/10 2017/08/10 rogid:sAQ34vRYj8W+D4ifvJAcA+rBwH46239 rogid:tWA8mxLeerefKvNZOERVljO8uHQ559292 rigid:25SaBDuOXt+A9EdzfA2U6kK0C6g false t7 tag:?-? sufficient binding region:126-626|glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39008 uniprotkb:P39016 intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C intact:EBI-2052996|uniprotkb:D6VTX5|ensemblfungi:YGL178W psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:mpt5_yeast(display_long)|uniprotkb:HTR1(gene name synonym)|uniprotkb:PUF5(gene name synonym)|uniprotkb:Protein HTR1(gene name synonym)|uniprotkb:BIC834(orf name)|uniprotkb:YGL178W(locus name)|uniprotkb:MPT5(gene name)|psi-mi:MPT5(display_short)|uniprotkb:Pumilio homology domain family member 5(gene name synonym) psi-mi:"MI:0096"(pull down) Goldstrohm et al. (2006) pubmed:16715093|doi:10.1038/nsmb1100|imex:IM-8387 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16226584|imex:IM-8387-8|dip:DIP-57083E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N refseq:NP_011337.1|sgd:S000003146|dip:DIP-2271N|mint:P39016|ensemblfungi:YGL178W(gene)|ensemblfungi:YGL178W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:5BYM|rcsb pdb:5BZ1|rcsb pdb:5BZ5|rcsb pdb:5BZU|rcsb pdb:5BZV psi-mi:"MI:0465"(dip) crc64:F3CAF97106A65933 crc64:6B289BAF3CEA2200 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/10 2017/08/10 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 rogid:tWA8mxLeerefKvNZOERVljO8uHQ559292 rigid:2fksR3lAc8Qy5ru10DkPE8Fo+/E false t7 tag:?-? glutathione s tranferase tag:n-n|sufficient binding region:126-626 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P31384 uniprotkb:P39016 intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C intact:EBI-2052996|uniprotkb:D6VTX5|ensemblfungi:YGL178W psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:mpt5_yeast(display_long)|uniprotkb:HTR1(gene name synonym)|uniprotkb:PUF5(gene name synonym)|uniprotkb:Protein HTR1(gene name synonym)|uniprotkb:BIC834(orf name)|uniprotkb:YGL178W(locus name)|uniprotkb:MPT5(gene name)|psi-mi:MPT5(display_short)|uniprotkb:Pumilio homology domain family member 5(gene name synonym) psi-mi:"MI:0096"(pull down) Goldstrohm et al. (2006) pubmed:16715093|doi:10.1038/nsmb1100|imex:IM-8387 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16226655|imex:IM-8387-4|dip:DIP-57084E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C refseq:NP_011337.1|sgd:S000003146|dip:DIP-2271N|mint:P39016|ensemblfungi:YGL178W(gene)|ensemblfungi:YGL178W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:5BYM|rcsb pdb:5BZ1|rcsb pdb:5BZ5|rcsb pdb:5BZU|rcsb pdb:5BZV psi-mi:"MI:0465"(dip) crc64:5CDB2E8FEDDBEF6F crc64:6B289BAF3CEA2200 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/10 2017/08/10 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 rogid:tWA8mxLeerefKvNZOERVljO8uHQ559292 rigid:kiASa6RpqvM5QFvsQwUW90l1Cvs false t7 tag:c-c glutathione s tranferase tag:n-n|sufficient binding region:126-626 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25339 uniprotkb:P39008 intact:EBI-23703|uniprotkb:D6VUC3|ensemblfungi:YGL014W intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C psi-mi:puf4_yeast(display_long)|uniprotkb:PUF4(gene name)|psi-mi:PUF4(display_short)|uniprotkb:YGL023(orf name)|uniprotkb:YGL014W(locus name) psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Goldstrohm et al. (2006) pubmed:16715093|doi:10.1038/nsmb1100|imex:IM-8387 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16226678|imex:IM-8387-5|dip:DIP-57088E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011501.1|sgd:S000002982|dip:DIP-2638N|mint:P25339|ensemblfungi:YGL014W(gene)|ensemblfungi:YGL014W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:3BWT|rcsb pdb:3BX2|rcsb pdb:3BX3|rcsb pdb:4DZS|go:"GO:0003729"(mRNA binding) sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N psi-mi:"MI:0465"(dip) crc64:659BA1062439F642 crc64:F3CAF97106A65933 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/10 2017/08/10 rogid:spjnSzTKOyi8X0oMi4wOTS+72hY559292 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 rigid:xN6KrY/U3BYoFn8643jhQD6w3zo false sufficient binding region:536-888|glutathione s tranferase tag:n-n t7 tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)