#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P03316 uniprotkb:P03316 intact:EBI-15562747|uniprotkb:C4T9C2|uniprotkb:P11259|uniprotkb:Q88870|uniprotkb:Q88871|uniprotkb:Q88872|uniprotkb:Q88873|uniprotkb:Q88874 intact:EBI-15562747|uniprotkb:C4T9C2|uniprotkb:P11259|uniprotkb:Q88870|uniprotkb:Q88871|uniprotkb:Q88872|uniprotkb:Q88873|uniprotkb:Q88874 psi-mi:pols_sindv(display_long)|uniprotkb:p130(gene name synonym) psi-mi:pols_sindv(display_long)|uniprotkb:p130(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Mukhopadhyay et al. (2006) pubmed:16407066|doi:10.1016/j.str.2005.07.025|imex:IM-8332 taxid:11034(sindv)|taxid:11034(Sindbis Virus) taxid:11034(sindv)|taxid:11034(Sindbis Virus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15562799|imex:IM-8332-1|dip:DIP-57032E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0055036"(virion membrane)|go:"GO:0061025"(membrane fusion)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0098029"(icosahedral viral capsid, spike)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000930(Peptidase S3, togavirin)|interpro:IPR000936(Alphavirus E2 glycoprotein)|interpro:IPR002533(Alphavirus E3 spike glycoprotein)|interpro:IPR002548(Alphavirus E1 glycoprotein)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR036253|interpro:IPR038055|interpro:IPR042304|interpro:IPR042305|interpro:IPR042306|interpro:IPR043504|rcsb pdb:1KXA|rcsb pdb:1KXB|rcsb pdb:1KXC|rcsb pdb:1KXD|rcsb pdb:1KXE|rcsb pdb:1KXF|rcsb pdb:1LD4|rcsb pdb:1SVP|rcsb pdb:1Z8Y|rcsb pdb:2SNV|rcsb pdb:2SNW|rcsb pdb:3J0F|rcsb pdb:3MUU|rcsb pdb:3MUW|go:"GO:0003723"(RNA binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039619"(T=4 icosahedral viral capsid)|refseq:NP_062890.1|dip:DIP-29032N go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0055036"(virion membrane)|go:"GO:0061025"(membrane fusion)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0098029"(icosahedral viral capsid, spike)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000930(Peptidase S3, togavirin)|interpro:IPR000936(Alphavirus E2 glycoprotein)|interpro:IPR002533(Alphavirus E3 spike glycoprotein)|interpro:IPR002548(Alphavirus E1 glycoprotein)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR036253|interpro:IPR038055|interpro:IPR042304|interpro:IPR042305|interpro:IPR042306|interpro:IPR043504|rcsb pdb:1KXA|rcsb pdb:1KXB|rcsb pdb:1KXC|rcsb pdb:1KXD|rcsb pdb:1KXE|rcsb pdb:1KXF|rcsb pdb:1LD4|rcsb pdb:1SVP|rcsb pdb:1Z8Y|rcsb pdb:2SNV|rcsb pdb:2SNW|rcsb pdb:3J0F|rcsb pdb:3MUU|rcsb pdb:3MUW|go:"GO:0003723"(RNA binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039619"(T=4 icosahedral viral capsid)|refseq:NP_062890.1|dip:DIP-29032N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/04 2017/08/10 rogid:tmOzuO93bwTmkI6KMSd1qaTisxs11034 rogid:tmOzuO93bwTmkI6KMSd1qaTisxs11034 rigid:W8KHFYsRWsuNv6n1spju0ywoJSc false sufficient binding region:329-751 sufficient binding region:807-1245 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03316 uniprotkb:P03316 intact:EBI-15562747|uniprotkb:C4T9C2|uniprotkb:P11259|uniprotkb:Q88870|uniprotkb:Q88871|uniprotkb:Q88872|uniprotkb:Q88873|uniprotkb:Q88874 intact:EBI-15562747|uniprotkb:C4T9C2|uniprotkb:P11259|uniprotkb:Q88870|uniprotkb:Q88871|uniprotkb:Q88872|uniprotkb:Q88873|uniprotkb:Q88874 psi-mi:pols_sindv(display_long)|uniprotkb:p130(gene name synonym) psi-mi:pols_sindv(display_long)|uniprotkb:p130(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Mukhopadhyay et al. (2006) pubmed:16407066|doi:10.1016/j.str.2005.07.025|imex:IM-8332 taxid:11034(sindv)|taxid:11034(Sindbis Virus) taxid:11034(sindv)|taxid:11034(Sindbis Virus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15562799|imex:IM-8332-1|dip:DIP-57032E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0055036"(virion membrane)|go:"GO:0061025"(membrane fusion)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0098029"(icosahedral viral capsid, spike)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000930(Peptidase S3, togavirin)|interpro:IPR000936(Alphavirus E2 glycoprotein)|interpro:IPR002533(Alphavirus E3 spike glycoprotein)|interpro:IPR002548(Alphavirus E1 glycoprotein)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR036253|interpro:IPR038055|interpro:IPR042304|interpro:IPR042305|interpro:IPR042306|interpro:IPR043504|rcsb pdb:1KXA|rcsb pdb:1KXB|rcsb pdb:1KXC|rcsb pdb:1KXD|rcsb pdb:1KXE|rcsb pdb:1KXF|rcsb pdb:1LD4|rcsb pdb:1SVP|rcsb pdb:1Z8Y|rcsb pdb:2SNV|rcsb pdb:2SNW|rcsb pdb:3J0F|rcsb pdb:3MUU|rcsb pdb:3MUW|go:"GO:0003723"(RNA binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039619"(T=4 icosahedral viral capsid)|refseq:NP_062890.1|dip:DIP-29032N go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0055036"(virion membrane)|go:"GO:0061025"(membrane fusion)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0098029"(icosahedral viral capsid, spike)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000930(Peptidase S3, togavirin)|interpro:IPR000936(Alphavirus E2 glycoprotein)|interpro:IPR002533(Alphavirus E3 spike glycoprotein)|interpro:IPR002548(Alphavirus E1 glycoprotein)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR036253|interpro:IPR038055|interpro:IPR042304|interpro:IPR042305|interpro:IPR042306|interpro:IPR043504|rcsb pdb:1KXA|rcsb pdb:1KXB|rcsb pdb:1KXC|rcsb pdb:1KXD|rcsb pdb:1KXE|rcsb pdb:1KXF|rcsb pdb:1LD4|rcsb pdb:1SVP|rcsb pdb:1Z8Y|rcsb pdb:2SNV|rcsb pdb:2SNW|rcsb pdb:3J0F|rcsb pdb:3MUU|rcsb pdb:3MUW|go:"GO:0003723"(RNA binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039619"(T=4 icosahedral viral capsid)|refseq:NP_062890.1|dip:DIP-29032N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/04 2017/08/10 rogid:tmOzuO93bwTmkI6KMSd1qaTisxs11034 rogid:tmOzuO93bwTmkI6KMSd1qaTisxs11034 rigid:W8KHFYsRWsuNv6n1spju0ywoJSc false sufficient binding region:329-751 sufficient binding region:1-264 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)